|
Name |
Accession |
Description |
Interval |
E-value |
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
210-592 |
4.16e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 121.96 E-value: 4.16e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 210 SELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNhlvslpsEAFAGNKELRELH 289
Cdd:COG4886 47 LLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELDLSGN-------EELSNLTNLESLD 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 290 LQGNDLYELPKGLlHRLEQLLVLDLSGNQLTShhvDNSTFAGLIRLIVLNLSNNALTRIgSKTFKELYFLQILDMRNNSI 369
Cdd:COG4886 120 LSGNQLTDLPEEL-ANLTNLKELDLSNNQLTD---LPEPLGNLTNLKSLDLSNNQLTDL-PEELGNLTNLKELDLSNNQI 194
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 370 GHIEEgAFLPLYNLHTLNLAENRLHTLDNRIFNgLYVLTKLTLNNNLVSIVESqaFRNCSDLKELDLSSNQLTEVPEAVQ 449
Cdd:COG4886 195 TDLPE-PLGNLTNLEELDLSGNQLTDLPEPLAN-LTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLAN 270
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 450 dLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNItvgmfqdLPRLSVLNLAKNRIQSIERGAFDKNTEIEAI 529
Cdd:COG4886 271 -LTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLL-------ELLILLLLLTTLLLLLLLLKGLLVTLTTLAL 342
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17136634 530 RLDKNFLTDINGIFATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQE 592
Cdd:COG4886 343 SLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTL 405
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
210-607 |
4.44e-29 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 121.58 E-value: 4.44e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 210 SELQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELH 289
Cdd:COG4886 23 TLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTDLGDLTNLTELD 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 290 LQGNDLyelpkglLHRLEQLLVLDLSGNQLTShhvDNSTFAGLIRLIVLNLSNNALTRIGSkTFKELYFLQILDMRNNSI 369
Cdd:COG4886 103 LSGNEE-------LSNLTNLESLDLSGNQLTD---LPEELANLTNLKELDLSNNQLTDLPE-PLGNLTNLKSLDLSNNQL 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 370 GHIEEgAFLPLYNLHTLNLAENRLHTLDNRIFNgLYVLTKLTLNNNLVSIVeSQAFRNCSDLKELDLSSNQLTEVPEaVQ 449
Cdd:COG4886 172 TDLPE-ELGNLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNNQLTDLPE-LG 247
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 450 DLSMLKTLDLGENQISEFKNNTfrNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIErgAFDKNTEIEAI 529
Cdd:COG4886 248 NLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLE--LLILLLLLTTL 323
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 530 RLDKNFLTDINGIFATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRIT 607
Cdd:COG4886 324 LLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVL 401
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
212-608 |
2.40e-28 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 119.65 E-value: 2.40e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 212 LQTLDVSFNELRSLPDAWGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQ 291
Cdd:COG4886 1 LLLLLLSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 292 GNDLYELPKGLLHRLEQLLVLDLSGNQltshhvdnsTFAGLIRLIVLNLSNNALTRIGsKTFKELYFLQILDMRNNSIGH 371
Cdd:COG4886 81 LLSLLLLGLTDLGDLTNLTELDLSGNE---------ELSNLTNLESLDLSGNQLTDLP-EELANLTNLKELDLSNNQLTD 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 372 IEEgAFLPLYNLHTLNLAENRLHTLDNRIFNgLYVLTKLTLNNNLVSIVeSQAFRNCSDLKELDLSSNQLTEVPEAVQDL 451
Cdd:COG4886 151 LPE-PLGNLTNLKSLDLSNNQLTDLPEELGN-LTNLKELDLSNNQITDL-PEPLGNLTNLEELDLSGNQLTDLPEPLANL 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 452 SMLKTLDLGENQISEFKNntFRNLNQLTGLRLIDNRIGNITVGMfqDLPRLSVLNLAKNRIQSIERGAFDKNTEIEAIRL 531
Cdd:COG4886 228 TNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLA--NLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLL 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 532 DKNFLTDINGIFA---TLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQEEIRVTTLDASHNRITE 608
Cdd:COG4886 304 LLLLLNLLELLILlllLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLA 383
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
273-609 |
4.55e-26 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 112.72 E-value: 4.55e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 273 SLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGNQLTSHHVDNSTFAGLIRLIVLNLSNNALTRIGSKT 352
Cdd:COG4886 12 LLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLRDLLLSSLLLLLSLLLLLLLSLLLLSLLLLGLTD 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 353 FKELYFLQILDMRNNSighieegAFLPLYNLHTLNLAENRLHTLDNRIFNgLYVLTKLTLNNNLVSIVESqAFRNCSDLK 432
Cdd:COG4886 92 LGDLTNLTELDLSGNE-------ELSNLTNLESLDLSGNQLTDLPEELAN-LTNLKELDLSNNQLTDLPE-PLGNLTNLK 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 433 ELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFKnNTFRNLNQLTGLRLIDNRIGNITVGmFQDLPRLSVLNLAKNRI 512
Cdd:COG4886 163 SLDLSNNQLTDLPEELGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQL 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 513 QSIErgAFDKNTEIEAIRLDKNFLTDINGIfATLASLLWLNLSENHLVWFDYAFIPSNLKWLDIHGNYIEALGNYYKLQE 592
Cdd:COG4886 241 TDLP--ELGNLTNLEELDLSNNQLTDLPPL-ANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILL 317
|
330
....*....|....*..
gi 17136634 593 EIRVTTLDASHNRITEI 609
Cdd:COG4886 318 LLLTTLLLLLLLLKGLL 334
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
325-710 |
5.96e-24 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 106.56 E-value: 5.96e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 325 DNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGA-FLPLYNLHTLNLAENRLHTLDNRIFNG 403
Cdd:COG4886 6 LSLTLKLLLLLLLELLTTLILLLLLLLLLLALLLLSLLSLLLLLTLLLSLLLrDLLLSSLLLLLSLLLLLLLSLLLLSLL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 404 LYVLTKLTLNNNL--VSIVESQAFRNCSDLKELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFkNNTFRNLNQLTGL 481
Cdd:COG4886 86 LLGLTDLGDLTNLteLDLSGNEELSNLTNLESLDLSGNQLTDLPEELANLTNLKELDLSNNQLTDL-PEPLGNLTNLKSL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 482 RLIDNRIGNITVGmFQDLPRLSVLNLAKNRIQSIErGAFDKNTEIEAIRLDKNFLTDINGIFATLASLLWLNLSENHLvw 561
Cdd:COG4886 165 DLSNNQLTDLPEE-LGNLTNLKELDLSNNQITDLP-EPLGNLTNLEELDLSGNQLTDLPEPLANLTNLETLDLSNNQL-- 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 562 fdyafipsnlkwldihgNYIEALGNYYKLQEeirvttLDASHNRITEIGAMSVPNSIELLFINNNIIGQIQANTFVDKTR 641
Cdd:COG4886 241 -----------------TDLPELGNLTNLEE------LDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLG 297
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17136634 642 LARVDLYANVLSKISLNALRVAPVSAEKPVPEFYLGGNPFECDCSMEWLQRINNLTTRQHPHVVDLGNI 710
Cdd:COG4886 298 LNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLL 366
|
|
| TIR |
smart00255 |
Toll - interleukin 1 - resistance; |
1045-1183 |
2.96e-23 |
|
Toll - interleukin 1 - resistance;
Pssm-ID: 214587 [Multi-domain] Cd Length: 140 Bit Score: 97.01 E-value: 2.96e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 1045 YDAIILHSEKDyeFVCRNIAAELEHGRPPFRLCIQQRDLPPQASHLQ-LVEGARASRKIILVLTRNLLATEWNRIEFRNA 1123
Cdd:smart00255 2 YDVFISYSGKE--DVRNEFLSHLLEKLRGYGLCVFIDDFEPGGGDLEeIDEAIEKSRIAIVVLSPNYAESEWCLDELVAA 79
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17136634 1124 FHESLRGLAQKLVIIEETSV-SAEAEDVAELSPYLKSVPSNRLLTCDRYFWEKLRYAIPIE 1183
Cdd:smart00255 80 LENALEEGGLRVIPIFYEVIpSDVRKQPGKFRKVFKKNYLKWPEDEKEQFWKKALYAVPSK 140
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
86-398 |
2.31e-18 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 89.22 E-value: 2.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 86 FRQLQKLSELRIDACKLQRVPPnAFEGLMSLKRLTLeSHNAVwgpgKTLelhGQSFQGLKELSELHLGDNNIRQLPEGVw 165
Cdd:COG4886 109 LSNLTNLESLDLSGNQLTDLPE-ELANLTNLKELDL-SNNQL----TDL---PEPLGNLTNLKSLDLSNNQLTDLPEEL- 178
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 166 CSMPSLQLLNLTQNRIRS-AEFLGFSEKL----CAGSALSNANGAVSGGSELQTLDVSFNELRSLPDawgASRLRRLQTL 240
Cdd:COG4886 179 GNLTNLKELDLSNNQITDlPEPLGNLTNLeeldLSGNQLTDLPEPLANLTNLETLDLSNNQLTDLPE---LGNLTNLEEL 255
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 241 SLQHNNISTLAPnaLAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGNQLT 320
Cdd:COG4886 256 DLSNNQLTDLPP--LANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLILLLLLTTLLLLLLLLKGL 333
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 321 SHHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLDN 398
Cdd:COG4886 334 LVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLLTTTAGVLLLTLALLDAV 411
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
132-662 |
9.93e-18 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 89.52 E-value: 9.93e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 132 KTLELHGQSFQG--------LKELSELHLGDNNIR-QLPEGVWCSMPSLQLLNLTQNrirsaeflgfseklcagsalsNA 202
Cdd:PLN00113 72 VSIDLSGKNISGkissaifrLPYIQTINLSNNQLSgPIPDDIFTTSSSLRYLNLSNN---------------------NF 130
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 203 NGAVSGGS--ELQTLDVSFNELR-SLPDAWGAsrLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLV-SLPSEa 278
Cdd:PLN00113 131 TGSIPRGSipNLETLDLSNNMLSgEIPNDIGS--FSSLKVLDLGGNVLVGKIPNSLTNLTSLEFLTLASNQLVgQIPRE- 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 279 FAGNKELRELHLQGNDLY-ELPKGlLHRLEQLLVLDLSGNQLT-----------------------SHHVDNSTFaGLIR 334
Cdd:PLN00113 208 LGQMKSLKWIYLGYNNLSgEIPYE-IGGLTSLNHLDLVYNNLTgpipsslgnlknlqylflyqnklSGPIPPSIF-SLQK 285
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 335 LIVLNLSNNALTRIGSKTFKELYFLQILDM-RNNSIGHIEEG-AFLPlyNLHTLNLAENRLHTLDNRIFNGLYVLTKLTL 412
Cdd:PLN00113 286 LISLDLSDNSLSGEIPELVIQLQNLEILHLfSNNFTGKIPVAlTSLP--RLQVLQLWSNKFSGEIPKNLGKHNNLTVLDL 363
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 413 NNNLVSIVESQAFRNCSDLKELDLSSNQL-TEVPEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRI-GN 490
Cdd:PLN00113 364 STNNLTGEIPEGLCSSGNLFKLILFSNSLeGEIPKSLGACRSLRRVRLQDNSFSGELPSEFTKLPLVYFLDISNNNLqGR 443
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 491 ITVGMFqDLPRLSVLNLAKNRIqSIERGAFDKNTEIEAIRLDKN-FLTDINGIFATLASLLWLNLSENHLVwfdyAFIPS 569
Cdd:PLN00113 444 INSRKW-DMPSLQMLSLARNKF-FGGLPDSFGSKRLENLDLSRNqFSGAVPRKLGSLSELMQLKLSENKLS----GEIPD 517
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 570 NLKWLDihgnyiealgnyyklqeeiRVTTLDASHNRITeigamsvpnsiellfinnniiGQIQAnTFVDKTRLARVDLYA 649
Cdd:PLN00113 518 ELSSCK-------------------KLVSLDLSHNQLS---------------------GQIPA-SFSEMPVLSQLDLSQ 556
|
570
....*....|....
gi 17136634 650 NVLS-KISLNALRV 662
Cdd:PLN00113 557 NQLSgEIPKNLGNV 570
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
775-920 |
3.11e-15 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 79.59 E-value: 3.11e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 775 IVDCGRQDLAALPNRIPQ--DVSDLYLDGNNMPEL--EVGHLTgrrNLRALYLNASNLMTLQNgSLAQLVNLRVLHLENN 850
Cdd:COG4886 117 SLDLSGNQLTDLPEELANltNLKELDLSNNQLTDLpePLGNLT---NLKSLDLSNNQLTDLPE-ELGNLTNLKELDLSNN 192
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 851 KLTALeGTEFRSLGLLRELYLHNNMLTHISNAtFEPLVSLEVLRLDNNRLSSLPHLQYRHSLQGLTLGRN 920
Cdd:COG4886 193 QITDL-PEPLGNLTNLEELDLSGNQLTDLPEP-LANLTNLETLDLSNNQLTDLPELGNLTNLEELDLSNN 260
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
105-586 |
8.82e-15 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 79.89 E-value: 8.82e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 105 VPPNAFEGLMSLKRLTLeSHNAVWGPG--------KTLELHGQSFQG--------LKELSELHLGDNNIRQLPEGVWCSM 168
Cdd:PLN00113 109 IPDDIFTTSSSLRYLNL-SNNNFTGSIprgsipnlETLDLSNNMLSGeipndigsFSSLKVLDLGGNVLVGKIPNSLTNL 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 169 PSLQLLNLTQN-----------RIRSAE--FLGFSeklcagsalsNANGAV----SGGSELQTLDVSFNELR-SLPDAWG 230
Cdd:PLN00113 188 TSLEFLTLASNqlvgqiprelgQMKSLKwiYLGYN----------NLSGEIpyeiGGLTSLNHLDLVYNNLTgPIPSSLG 257
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 231 asRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLY-ELPKGL--LHRLE 307
Cdd:PLN00113 258 --NLKNLQYLFLYQNKLSGPIPPSIFSLQKLISLDLSDNSLSGEIPELVIQLQNLEILHLFSNNFTgKIPVALtsLPRLQ 335
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 308 ---------------------QLLVLDLSGNQLTSHHVDNSTFAG-LIRLIVLN---------------------LSNNA 344
Cdd:PLN00113 336 vlqlwsnkfsgeipknlgkhnNLTVLDLSTNNLTGEIPEGLCSSGnLFKLILFSnslegeipkslgacrslrrvrLQDNS 415
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 345 LTRIGSKTFKELYFLQILDMRNNSI-GHIEEGAFlPLYNLHTLNLAENRLhtldnriFNGL------YVLTKLTLNNNLV 417
Cdd:PLN00113 416 FSGELPSEFTKLPLVYFLDISNNNLqGRINSRKW-DMPSLQMLSLARNKF-------FGGLpdsfgsKRLENLDLSRNQF 487
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 418 SIVESQAFRNCSDLKELDLSSNQLT-EVPEAVQDLSMLKTLDLGENQISefknntfrnlnqltglrlidnriGNITVGmF 496
Cdd:PLN00113 488 SGAVPRKLGSLSELMQLKLSENKLSgEIPDELSSCKKLVSLDLSHNQLS-----------------------GQIPAS-F 543
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 497 QDLPRLSVLNLAKNRIQsierGAFDKNteieairldknfltdingiFATLASLLWLNLSENHLvwfdYAFIPSNLKWLDI 576
Cdd:PLN00113 544 SEMPVLSQLDLSQNQLS----GEIPKN-------------------LGNVESLVQVNISHNHL----HGSLPSTGAFLAI 596
|
570
....*....|
gi 17136634 577 HGNYIEalGN 586
Cdd:PLN00113 597 NASAVA--GN 604
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
144-372 |
2.18e-14 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 73.67 E-value: 2.18e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 144 LKELSELHLGDNNIRQLPEGVWCsmPSLQLLNLTQNRIRSAEFLGFseklcagsalsnangavsggselqtldvsfnelr 223
Cdd:cd21340 1 LKRITHLYLNDKNITKIDNLSLC--KNLKVLYLYDNKITKIENLEF---------------------------------- 44
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 224 slpdawgasrLRRLQTLSLQHNNISTLAPnaLAGLSSLRVLNISYNHLVSLpsEAFAGNKELRELHLQGNDLyelPKG-- 301
Cdd:cd21340 45 ----------LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRISVV--EGLENLTNLEELHIENQRL---PPGek 107
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 302 -------LLHRLEQLLVLDLSGNQLTSHhvdnSTFAGLIRLIVLNLSNNALTRIG--SKTFKELYFLQILDMRNNSIGHI 372
Cdd:cd21340 108 ltfdprsLAALSNSLRVLNISGNNIDSL----EPLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVCKK 183
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
797-1032 |
5.68e-14 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 75.74 E-value: 5.68e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 797 LYLDGNNMPEL--EVGHLTgrrNLRALYLNASNLMTLQNgSLAQLVNLRVLHLENNKLTALeGTEFRSLGLLRELYLHNN 874
Cdd:COG4886 164 LDLSNNQLTDLpeELGNLT---NLKELDLSNNQITDLPE-PLGNLTNLEELDLSGNQLTDL-PEPLANLTNLETLDLSNN 238
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 875 MLTHISNatFEPLVSLEVLRLDNNRLSSLPHLQYRHSLQGLTLGRNAWSCRCQQLRELAQFVSDNAMVVRDAHDIYCLDA 954
Cdd:COG4886 239 QLTDLPE--LGNLTNLEELDLSNNQLTDLPPLANLTNLKTLDLSNNQLTDLKLKELELLLGLNSLLLLLLLLNLLELLIL 316
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 955 GIKRELELIGNLANGPDCSDLLDASASNISSSQDLAGGYRLPLLAAVLVLIFLVVVLIIVFVFRESVRMWLFAHYGVR 1032
Cdd:COG4886 317 LLLLTTLLLLLLLLKGLLVTLTTLALSLSLLALLTLLLLLNLLSLLLTLLLTLGLLGLLEATLLTLALLLLTLLLLLL 394
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
288-488 |
6.47e-13 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 69.43 E-value: 6.47e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 288 LHLQGNDLYELPKglLHRLEQLLVLDLSGNQLTShhVDNstFAGLIRLIVLNLSNNALTRIGSktFKELYFLQILDMRNN 367
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITK--IEN--LEFLTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 368 SIGHIEegaflplyNLHTL-NLAEnrLHTLDNRIFNGlyvlTKLTLN-NNLVSIVESqafrncsdLKELDLSSNQLTEVp 445
Cdd:cd21340 79 RISVVE--------GLENLtNLEE--LHIENQRLPPG----EKLTFDpRSLAALSNS--------LRVLNISGNNIDSL- 135
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 17136634 446 EAVQDLSMLKTLDLGENQISEFKN--NTFRNLNQLTGLRLIDNRI 488
Cdd:cd21340 136 EPLAPLRNLEQLDASNNQISDLEEllDLLSSWPSLRELDLTGNPV 180
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
235-295 |
9.43e-13 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 64.08 E-value: 9.43e-13
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17136634 235 RRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDL 295
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
841-900 |
4.54e-12 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 62.16 E-value: 4.54e-12
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 841 NLRVLHLENNKLTALEGTEFRSLGLLRELYLHNNMLTHISNATFEPLVSLEVLRLDNNRL 900
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
821-991 |
8.45e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 66.35 E-value: 8.45e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 821 LYLNASNLMTLQNgsLAQLVNLRVLHLENNKLTALEGTEFrsLGLLRELYLHNNMLTHISNatFEPLVSLEVLRLDNNRL 900
Cdd:cd21340 7 LYLNDKNITKIDN--LSLCKNLKVLYLYDNKITKIENLEF--LTNLTHLYLQNNQIEKIEN--LENLVNLKKLYLGGNRI 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 901 SSLPHLQYRHSLQGLTLGRnawscrcQQLRELAQFVSDNAMVvrdahdiycldAGIKRELELignlangpdcsdlLDASA 980
Cdd:cd21340 81 SVVEGLENLTNLEELHIEN-------QRLPPGEKLTFDPRSL-----------AALSNSLRV-------------LNISG 129
|
170
....*....|.
gi 17136634 981 SNISSSQDLAG 991
Cdd:cd21340 130 NNIDSLEPLAP 140
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
234-418 |
9.64e-12 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 65.96 E-value: 9.64e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 234 LRRLQTLSLQHNNISTLapNALAGLSSLRVLnisY---NHLVSLpsEAFAGNKELRELHLQGNDLYELPKglLHRLEQLL 310
Cdd:cd21340 1 LKRITHLYLNDKNITKI--DNLSLCKNLKVL---YlydNKITKI--ENLEFLTNLTHLYLQNNQIEKIEN--LENLVNLK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 311 VLDLSGNQLTshHVDNstFAGLIRLIVLNLSNNALTRIGSKTFKE------LYFLQILDMRNNSIGHIEEgaFLPLYNLH 384
Cdd:cd21340 72 KLYLGGNRIS--VVEG--LENLTNLEELHIENQRLPPGEKLTFDPrslaalSNSLRVLNISGNNIDSLEP--LAPLRNLE 145
|
170 180 190
....*....|....*....|....*....|....*.
gi 17136634 385 TLNLAENRLHTLDN--RIFNGLYVLTKLTLNNNLVS 418
Cdd:cd21340 146 QLDASNNQISDLEEllDLLSSWPSLRELDLTGNPVC 181
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
93-360 |
1.07e-11 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 69.73 E-value: 1.07e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 93 SELRIDACKLQRVPPNAFEGLMSLkrlTLESHNAVWGPGKtleLHGQsfqglkeLSELHLGDNNIRQLPEgvwcSMP-SL 171
Cdd:PRK15370 181 TELRLKILGLTTIPACIPEQITTL---ILDNNELKSLPEN---LQGN-------IKTLYANSNQLTSIPA----TLPdTI 243
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 172 QLLNLTQNRIrsaefLGFSEKLcagsalsnangavsgGSELQTLDVSFNELRSLPDawgaSRLRRLQTLSLQHNNISTLA 251
Cdd:PRK15370 244 QEMELSINRI-----TELPERL---------------PSALQSLDLFHNKISCLPE----NLPEELRYLSVYDNSIRTLP 299
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 252 PNALAGLSSLRVLNisyNHLVSLPSEAFAGnkeLRELHLQGNDLYELPKGLLHRLEqllVLDLSGNQLTshhVDNSTFAG 331
Cdd:PRK15370 300 AHLPSGITHLNVQS---NSLTALPETLPPG---LKTLEAGENALTSLPASLPPELQ---VLDVSKNQIT---VLPETLPP 367
|
250 260
....*....|....*....|....*....
gi 17136634 332 LIRliVLNLSNNALTRIGSKTFKELYFLQ 360
Cdd:PRK15370 368 TIT--TLDVSRNALTNLPENLPAALQIMQ 394
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
210-271 |
1.42e-11 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 61.00 E-value: 1.42e-11
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17136634 210 SELQTLDVSFNELRSLPDAWgASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHL 271
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGA-FKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
210-464 |
1.76e-11 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 67.00 E-value: 1.76e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 210 SELQTLDVSFNELRSLPDAWGA-----SRLRRLQTLSLQHNNISTLAPNALaglsslrvlnisynhlvslpsEAFAGNKE 284
Cdd:cd00116 51 PSLKELCLSLNETGRIPRGLQSllqglTKGCGLQELDLSDNALGPDGCGVL---------------------ESLLRSSS 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 285 LRELHLQGNDLYELP-----KGLLHRLEQLLVLDLSGNQLTSHHVDN--STFAGLIRLIVLNLSNNALTRIGSKT----F 353
Cdd:cd00116 110 LQELKLNNNGLGDRGlrllaKGLKDLPPALEKLVLGRNRLEGASCEAlaKALRANRDLKELNLANNGIGDAGIRAlaegL 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 354 KELYFLQILDMRNNSIGHIE----EGAFLPLYNLHTLNLAENRL-----HTLDNRIFNGLYVLTKLTLNNNLV----SIV 420
Cdd:cd00116 190 KANCNLEVLDLNNNGLTDEGasalAETLASLKSLEVLNLGDNNLtdagaAALASALLSPNISLLTLSLSCNDItddgAKD 269
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|
gi 17136634 421 ESQAFRNCSDLKELDLSSNQLTEVPEAVQDLS------MLKTLDLGENQI 464
Cdd:cd00116 270 LAEVLAEKESLLELDLRGNKFGEEGAQLLAESllepgnELESLWVKDDSF 319
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
110-378 |
3.24e-11 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 66.22 E-value: 3.24e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 110 FEGLMSLKRLTLESHNAVWGPGKTLelhGQSFQGLKELSELHLGDNNIRQLPEGVWCSM------PSLQLLNLTQNrirs 183
Cdd:cd00116 19 LPKLLCLQVLRLEGNTLGEEAAKAL---ASALRPQPSLKELCLSLNETGRIPRGLQSLLqgltkgCGLQELDLSDN---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 184 aeflGFSEKLCAGSAlsnangAVSGGSELQTLDVSFNEL---------RSLPDAwgASRLRRLQtlsLQHNNISTLAPNA 254
Cdd:cd00116 92 ----ALGPDGCGVLE------SLLRSSSLQELKLNNNGLgdrglrllaKGLKDL--PPALEKLV---LGRNRLEGASCEA 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 255 LAGL----SSLRVLNISYNHL----VSLPSEAFAGNKELRELHLQGNDLYELP----KGLLHRLEQLLVLDLSGNQLTSH 322
Cdd:cd00116 157 LAKAlranRDLKELNLANNGIgdagIRALAEGLKANCNLEVLDLNNNGLTDEGasalAETLASLKSLEVLNLGDNNLTDA 236
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17136634 323 ---HVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYF----LQILDMRNNSIGhiEEGAFL 378
Cdd:cd00116 237 gaaALASALLSPNISLLTLSLSCNDITDDGAKDLAEVLAekesLLELDLRGNKFG--EEGAQL 297
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
346-479 |
1.41e-10 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 60.25 E-value: 1.41e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 346 TRIGSKTFKE--LYFLQIldmrNNSIGHIEEGAFLPLYNLHTLNLAENrLHTLDNRIFNGLYvLTKLTLNNNLVSIvESQ 423
Cdd:pfam13306 1 TSIGSYAFYNcsLTSITI----PSSLTSIGEYAFSNCTSLKSITLPSS-LTSIGSYAFYNCS-LTSITIPSSLTSI-GEY 73
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 17136634 424 AFRNCSDLKELDLSSNqLTEVPEAVQDLSMLKTLDLGENqISEFKNNTFRNLNQLT 479
Cdd:pfam13306 74 AFSNCSNLKSITLPSN-LTSIGSYAFSNCSLKSITIPSS-VTTIGSYAFSNCSNLK 127
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
797-932 |
6.52e-10 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 60.57 E-value: 6.52e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 797 LYLDGNNMPELEVGHLTgrRNLRALYL------------NASNLMTL--QN------GSLAQLVNLRVLHLENNKLTALE 856
Cdd:cd21340 7 LYLNDKNITKIDNLSLC--KNLKVLYLydnkitkienleFLTNLTHLylQNnqiekiENLENLVNLKKLYLGGNRISVVE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 857 GTEfrSLGLLRELYLHNNMLTHISNATFEP------LVSLEVLRLDNNRLSSLPHLQYRHSLQGLTLGRNAWS------- 923
Cdd:cd21340 85 GLE--NLTNLEELHIENQRLPPGEKLTFDPrslaalSNSLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISdleelld 162
|
170
....*....|.
gi 17136634 924 --CRCQQLREL 932
Cdd:cd21340 163 llSSWPSLREL 173
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
382-441 |
6.64e-10 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 55.99 E-value: 6.64e-10
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 382 NLHTLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQL 441
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR |
COG4886 |
Leucine-rich repeat (LRR) protein [Transcription]; |
833-939 |
3.09e-09 |
|
Leucine-rich repeat (LRR) protein [Transcription];
Pssm-ID: 443914 [Multi-domain] Cd Length: 414 Bit Score: 60.72 E-value: 3.09e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 833 NGSLAQLVNLRVLHLENNKLTALeGTEFRSLGLLRELYLHNNMLTHISNAtFEPLVSLEVLRLDNNRLSSLP-HLQYRHS 911
Cdd:COG4886 106 NEELSNLTNLESLDLSGNQLTDL-PEELANLTNLKELDLSNNQLTDLPEP-LGNLTNLKSLDLSNNQLTDLPeELGNLTN 183
|
90 100 110
....*....|....*....|....*....|....
gi 17136634 912 LQGLTLGRNAWS------CRCQQLRELAqfVSDN 939
Cdd:COG4886 184 LKELDLSNNQITdlpeplGNLTNLEELD--LSGN 215
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
816-876 |
7.67e-09 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 53.30 E-value: 7.67e-09
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17136634 816 RNLRALYLNASNLMTLQNGSLAQLVNLRVLHLENNKLTALEGTEFRSLGLLRELYLHNNML 876
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
407-464 |
5.88e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 5.88e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17136634 407 LTKLTLNNNLVSIVESQAFRNCSDLKELDLSSNQLTEV-PEAVQDLSMLKTLDLGENQI 464
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLsPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
334-393 |
6.81e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.60 E-value: 6.81e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 334 RLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRL 393
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN00113 |
PLN00113 |
leucine-rich repeat receptor-like protein kinase; Provisional |
83-345 |
7.13e-08 |
|
leucine-rich repeat receptor-like protein kinase; Provisional
Pssm-ID: 215061 [Multi-domain] Cd Length: 968 Bit Score: 57.17 E-value: 7.13e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 83 PGLFRQLQKLSELRIDACKLQRVPPNAFEGLMSLKRLTLESHNAVWGPGKTLELHgqsfqglKELSELHLGDNNIR-QLP 161
Cdd:PLN00113 301 PELVIQLQNLEILHLFSNNFTGKIPVALTSLPRLQVLQLWSNKFSGEIPKNLGKH-------NNLTVLDLSTNNLTgEIP 373
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 162 EGVwCSMPSLQLLNLTQN-----------------RIRSAEFlGFSEKLCAGSA---------LSNAN--GAVSGGS--- 210
Cdd:PLN00113 374 EGL-CSSGNLFKLILFSNslegeipkslgacrslrRVRLQDN-SFSGELPSEFTklplvyfldISNNNlqGRINSRKwdm 451
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 211 -ELQTLDVSFNE-LRSLPDAWGASRLRRlqtLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELREL 288
Cdd:PLN00113 452 pSLQMLSLARNKfFGGLPDSFGSKRLEN---LDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSGEIPDELSSCKKLVSL 528
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 289 HLQGNDLY-ELPKGlLHRLEQLLVLDLSGNQLTSHHVDNstFAGLIRLIVLNLSNNAL 345
Cdd:PLN00113 529 DLSHNQLSgQIPAS-FSEMPVLSQLDLSQNQLSGEIPKN--LGNVESLVQVNISHNHL 583
|
|
| LRRCT |
smart00082 |
Leucine rich repeat C-terminal domain; |
679-736 |
7.73e-08 |
|
Leucine rich repeat C-terminal domain;
Pssm-ID: 214507 [Multi-domain] Cd Length: 51 Bit Score: 50.12 E-value: 7.73e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 679 NPFECDCSMEWLQRINNLTTrqhpHVVDLGNIECLMPHSRSAPLRPlasLSASDFVCK 736
Cdd:smart00082 1 NPFICDCELRWLLRWLQANE----HLQDPVDLRCASPSSLRGPLLE---LLHSEFKCP 51
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
258-559 |
8.27e-08 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 55.82 E-value: 8.27e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 258 LSSLRVLNISYNHL----VSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLLvldlSGNQLTShhvdnstfagli 333
Cdd:cd00116 22 LLCLQVLRLEGNTLgeeaAKALASALRPQPSLKELCLSLNETGRIPRGLQSLLQGLT----KGCGLQE------------ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 334 rlivLNLSNNALTRIGSKTFKEL---YFLQILDMRNNSIG-----HIEEGAFLPLYNLHTLNLAENRLhtldnrifngly 405
Cdd:cd00116 86 ----LDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGdrglrLLAKGLKDLPPALEKLVLGRNRL------------ 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 406 vltkltlnNNLVSIVESQAFRNCSDLKELDLSSNQLTE-----VPEAVQDLSMLKTLDLGENQISE----FKNNTFRNLN 476
Cdd:cd00116 150 --------EGASCEALAKALRANRDLKELNLANNGIGDagiraLAEGLKANCNLEVLDLNNNGLTDegasALAETLASLK 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 477 QLTGLRLIDNRIGN-----ITVGMFQDLPRLSVLNLAKNRIqsierGAFDKNTEIEAIRlDKnfltdingifatlASLLW 551
Cdd:cd00116 222 SLEVLNLGDNNLTDagaaaLASALLSPNISLLTLSLSCNDI-----TDDGAKDLAEVLA-EK-------------ESLLE 282
|
....*...
gi 17136634 552 LNLSENHL 559
Cdd:cd00116 283 LDLRGNKF 290
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
284-345 |
8.96e-08 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 50.22 E-value: 8.96e-08
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17136634 284 ELRELHLQGNDLYELPKGLLHRLEQLLVLDLSGNQLTshHVDNSTFAGLIRLIVLNLSNNAL 345
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLT--TLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
308-369 |
1.35e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.45 E-value: 1.35e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17136634 308 QLLVLDLSGNQLTshHVDNSTFAGLIRLIVLNLSNNALTRIGSKTFKELYFLQILDMRNNSI 369
Cdd:pfam13855 2 NLRSLDLSNNRLT--SLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
359-417 |
1.49e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 49.45 E-value: 1.49e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17136634 359 LQILDMRNNSIGHIEEGAFLPLYNLHTLNLAENRLHTLDNRIFNGLYVLTKLTLNNNLV 417
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
211-464 |
2.76e-07 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 55.09 E-value: 2.76e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 211 ELQTLDVSFNELRSLPDAWGASrlrrLQTLSLQHNNISTLaPNALAglSSLRVLNISYNHLVSLPSEAFAGnkeLRELHL 290
Cdd:PRK15370 200 QITTLILDNNELKSLPENLQGN----IKTLYANSNQLTSI-PATLP--DTIQEMELSINRITELPERLPSA---LQSLDL 269
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 291 QGNDLYELPKGLLhrlEQLLVLDLSGNQLTS--HHVDNStfaglirLIVLNLSNNALTrigsktfkelyFLQildmrnns 368
Cdd:PRK15370 270 FHNKISCLPENLP---EELRYLSVYDNSIRTlpAHLPSG-------ITHLNVQSNSLT-----------ALP-------- 320
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 369 ighieegAFLPLyNLHTLNLAENRLHTLDNRIFNGLYVLTklTLNNNLVSIVESQAfrncSDLKELDLSSNQLTEVPEAV 448
Cdd:PRK15370 321 -------ETLPP-GLKTLEAGENALTSLPASLPPELQVLD--VSKNQITVLPETLP----PTITTLDVSRNALTNLPENL 386
|
250
....*....|....*.
gi 17136634 449 QdlSMLKTLDLGENQI 464
Cdd:PRK15370 387 P--AALQIMQASRNNL 400
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
431-488 |
7.22e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.52 E-value: 7.22e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17136634 431 LKELDLSSNQLTEV-PEAVQDLSMLKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRI 488
Cdd:pfam13855 3 LRSLDLSNNRLTSLdDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
115-181 |
8.04e-07 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 47.52 E-value: 8.04e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17136634 115 SLKRLTLeSHNAVWGpgktleLHGQSFQGLKELSELHLGDNNIRQLPEGVWCSMPSLQLLNLTQNRI 181
Cdd:pfam13855 2 NLRSLDL-SNNRLTS------LDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
225-305 |
1.76e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 52.51 E-value: 1.76e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 225 LPDAWgaSRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPSEAFAGNKELRELHLQGNDLY-ELPKGL- 302
Cdd:PLN03150 434 IPNDI--SKLRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNGSIPESLGQLTSLRILNLNGNSLSgRVPAALg 511
|
....*.
gi 17136634 303 ---LHR 305
Cdd:PLN03150 512 grlLHR 517
|
|
| PRK15370 |
PRK15370 |
type III secretion system effector E3 ubiquitin transferase SlrP; |
92-275 |
2.02e-06 |
|
type III secretion system effector E3 ubiquitin transferase SlrP;
Pssm-ID: 185268 [Multi-domain] Cd Length: 754 Bit Score: 52.39 E-value: 2.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 92 LSELRIDACKLQRVPPNAFEGLMSLkrltLESHNAVWGPGKTLElhgqsfqglKELSELHLGDNNIRQLPEGVWCSMPSL 171
Cdd:PRK15370 243 IQEMELSINRITELPERLPSALQSL----DLFHNKISCLPENLP---------EELRYLSVYDNSIRTLPAHLPSGITHL 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 172 QLLNLTQNRIRSAEFLGFsEKLCAG-SALSNANGAVSggSELQTLDVSFNELRSLPDAWGASrlrrLQTLSLQHNNISTL 250
Cdd:PRK15370 310 NVQSNSLTALPETLPPGL-KTLEAGeNALTSLPASLP--PELQVLDVSKNQITVLPETLPPT----ITTLDVSRNALTNL 382
|
170 180
....*....|....*....|....*
gi 17136634 251 APNALAglsSLRVLNISYNHLVSLP 275
Cdd:PRK15370 383 PENLPA---ALQIMQASRNNLVRLP 404
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
477-559 |
3.75e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 45.59 E-value: 3.75e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 477 QLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRIQSIERGAFDKnteieairldknfltdingifatLASLLWLNLSE 556
Cdd:pfam13855 2 NLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSG-----------------------LPSLRYLDLSG 58
|
...
gi 17136634 557 NHL 559
Cdd:pfam13855 59 NRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
236-502 |
6.18e-06 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 50.56 E-value: 6.18e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 236 RLQTLSLQHNNISTLAP----NALAGLSSLRVLNISYNHLVSLPSEAFA----GNKELRELHLQGND-----LYELPKGL 302
Cdd:COG5238 181 SVETVYLGCNQIGDEGIeelaEALTQNTTVTTLWLKRNPIGDEGAEILAealkGNKSLTTLDLSNNQigdegVIALAEAL 260
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 303 LHRlEQLLVLDLSGNQLTSHHVD--NSTFAGLIRLIVLNLSNNALTRIGSKTFKELyflqildMRNNSIghieegaflpl 380
Cdd:COG5238 261 KNN-TTVETLYLSGNQIGAEGAIalAKALQGNTTLTSLDLSVNRIGDEGAIALAEG-------LQGNKT----------- 321
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 381 ynLHTLNLAENRLHTLD-NRIFNGLYVLTKLTlnnnlvsivesqafrncsdlkELDLSSNQLT-----EVPEAVQDLSML 454
Cdd:COG5238 322 --LHTLNLAYNGIGAQGaIALAKALQENTTLH---------------------SLDLSDNQIGdegaiALAKYLEGNTTL 378
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 17136634 455 KTLDLGENQISEFKNNTF---RNLNQLTGLRLIDNRIGN-ITVGMFQDLPRL 502
Cdd:COG5238 379 RELNLGKNNIGKQGAEALidaLQTNRLHTLILDGNLIGAeAQQRLEQLLERI 430
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
454-512 |
6.37e-06 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 44.82 E-value: 6.37e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 17136634 454 LKTLDLGENQISEFKNNTFRNLNQLTGLRLIDNRIGNITVGMFQDLPRLSVLNLAKNRI 512
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| LRR_RI |
cd00116 |
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 ... |
310-614 |
2.47e-05 |
|
Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond to structural units consisting of a beta strand (LxxLxLxxN/CxL conserved pattern) and an alpha helix. This alignment contains 12 strands corresponding to 11 full repeats, consistent with the extent observed in the subfamily acting as Ran GTPase Activating Proteins (RanGAP1).
Pssm-ID: 238064 [Multi-domain] Cd Length: 319 Bit Score: 48.12 E-value: 2.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 310 LVLDLSGNQLTSHHVDnSTFAGLIRLIVLNLSNNALTRIGSK-TFKEL---YFLQILDMRNNSIGHIEEGAFLPLYNLHT 385
Cdd:cd00116 1 LQLSLKGELLKTERAT-ELLPKLLCLQVLRLEGNTLGEEAAKaLASALrpqPSLKELCLSLNETGRIPRGLQSLLQGLTK 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 386 LNLaenrlhtldnrifnglyvLTKLTLNNNLVSIVESQAFRNC---SDLKELDLSSNQLTE-----VPEAVQDLSM-LKT 456
Cdd:cd00116 80 GCG------------------LQELDLSDNALGPDGCGVLESLlrsSSLQELKLNNNGLGDrglrlLAKGLKDLPPaLEK 141
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 457 LDLGENQISEfknntfRNLNQLTGLrlidnrignitvgmFQDLPRLSVLNLAKNRIQsiERG------AFDKNTEIEAIR 530
Cdd:cd00116 142 LVLGRNRLEG------ASCEALAKA--------------LRANRDLKELNLANNGIG--DAGiralaeGLKANCNLEVLD 199
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 531 LDKNFLTDINGI-----FATLASLLWLNLSENHLVWFDYAFIPSNLKwldihgnyiealgnyyklQEEIRVTTLDASHNR 605
Cdd:cd00116 200 LNNNGLTDEGASalaetLASLKSLEVLNLGDNNLTDAGAAALASALL------------------SPNISLLTLSLSCND 261
|
....*....
gi 17136634 606 ITEIGAMSV 614
Cdd:cd00116 262 ITDDGAKDL 270
|
|
| TIR_2 |
pfam13676 |
TIR domain; This is a family of Toll-like receptors. |
1049-1130 |
2.61e-05 |
|
TIR domain; This is a family of Toll-like receptors.
Pssm-ID: 463954 [Multi-domain] Cd Length: 118 Bit Score: 45.00 E-value: 2.61e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 1049 ILHSEKDYEFVcRNIAAELE-HGrppFRLCIQQRDLPPQAS-HLQLVEGARASRKIILVLTRNLLATEWNRIEFRNAFHE 1126
Cdd:pfam13676 3 ISYAGEDRAWA-EWLADALEaAG---YRVWLDRWDIRPGDDwVEEIEEAIENSDRVLVVLSPNYLESPWCRAEWEAALAD 78
|
....
gi 17136634 1127 SLRG 1130
Cdd:pfam13676 79 PEGR 82
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
90-157 |
5.86e-05 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 42.13 E-value: 5.86e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 90 QKLSELRIDACKLQRVPPNAFEGLMSLKRLTLeSHNAVwgpgktLELHGQSFQGLKELSELHLGDNNI 157
Cdd:pfam13855 1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDL-SNNLL------TTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
430-652 |
1.02e-04 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 46.32 E-value: 1.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 430 DLKELDLSSNQLTEVPEAVQDLSmLKTLDLGENQIS-----EFKNNTFRNlNQLTGLRLIDNRIGN----ITVGMFQDLP 500
Cdd:COG5238 159 LGLAARLGLLAAISMAKALQNNS-VETVYLGCNQIGdegieELAEALTQN-TTVTTLWLKRNPIGDegaeILAEALKGNK 236
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 501 RLSVLNLAKNRIQSIERGAFDK----NTEIEAIRLDKNFLTD-----INGIFATLASLLWLNLSENHL-----VwfdyAF 566
Cdd:COG5238 237 SLTTLDLSNNQIGDEGVIALAEalknNTTVETLYLSGNQIGAegaiaLAKALQGNTTLTSLDLSVNRIgdegaI----AL 312
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 567 IP-----SNLKWLDIHGNYI-----EALGNyyKLQEEIRVTTLDASHNRITEIGAMSVPNSIE----LLFIN--NNIIGQ 630
Cdd:COG5238 313 AEglqgnKTLHTLNLAYNGIgaqgaIALAK--ALQENTTLHSLDLSDNQIGDEGAIALAKYLEgnttLRELNlgKNNIGK 390
|
250 260
....*....|....*....|....*
gi 17136634 631 IQANTFVD---KTRLARVDLYANVL 652
Cdd:COG5238 391 QGAEALIDalqTNRLHTLILDGNLI 415
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
259-432 |
1.03e-04 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 43.30 E-value: 1.03e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 259 SSLRVLNISyNHLVSLPSEAFAGNKELRELHLqgndlyelpkgllhrleqllvldlsGNQLTShhVDNSTFaglirlivl 338
Cdd:pfam13306 11 CSLTSITIP-SSLTSIGEYAFSNCTSLKSITL-------------------------PSSLTS--IGSYAF--------- 53
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 339 nlSNNALTRIgskTFkelyflqildmrNNSIGHIEEGAFLPLYNLHTLNLAENrLHTLDNRIFNGLYvLTKLTLNNNLVS 418
Cdd:pfam13306 54 --YNCSLTSI---TI------------PSSLTSIGEYAFSNCSNLKSITLPSN-LTSIGSYAFSNCS-LKSITIPSSVTT 114
|
170
....*....|....
gi 17136634 419 IvESQAFRNCSDLK 432
Cdd:pfam13306 115 I-GSYAFSNCSNLK 127
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
132-320 |
1.04e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 46.69 E-value: 1.04e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 132 KTLELHGQSFQ-------GLKELSELHLGDNNIRQLPEGVwCSM--------------PSLQLLNLTQNRIrsAEFLGFS 190
Cdd:PRK15387 245 RTLEVSGNQLTslpvlppGLLELSIFSNPLTHLPALPSGL-CKLwifgnqltslpvlpPGLQELSVSDNQL--ASLPALP 321
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 191 EKLCAGSALSNANGAV-SGGSELQTLDVSFNELRSLPDAwgASRLRRLQTlslqHNNISTLAPNALAGLSSLRVlniSYN 269
Cdd:PRK15387 322 SELCKLWAYNNQLTSLpTLPSGLQELSVSDNQLASLPTL--PSELYKLWA----YNNRLTSLPALPSGLKELIV---SGN 392
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 17136634 270 HLVSLPSEAfagnKELRELHLQGNDLYELPKgllhRLEQLLVLDLSGNQLT 320
Cdd:PRK15387 393 RLTSLPVLP----SELKELMVSGNRLTSLPM----LPSGLLSLSVYRNQLT 435
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
797-852 |
1.24e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 41.36 E-value: 1.24e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*.
gi 17136634 797 LYLDGNNMPELEVGHLTGRRNLRALYLNASNLMTLQNGSLAQLVNLRVLHLENNKL 852
Cdd:pfam13855 6 LDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
|
|
| PRK15387 |
PRK15387 |
type III secretion system effector E3 ubiquitin transferase SspH2; |
211-480 |
2.02e-04 |
|
type III secretion system effector E3 ubiquitin transferase SspH2;
Pssm-ID: 185285 [Multi-domain] Cd Length: 788 Bit Score: 45.92 E-value: 2.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 211 ELQTLDVSFNELRSLPDAWGAsrlrrLQTLSLQHNNISTLaPNALAGLSSLRVLNisyNHLVSLPSEAfagnKELRELHL 290
Cdd:PRK15387 243 ELRTLEVSGNQLTSLPVLPPG-----LLELSIFSNPLTHL-PALPSGLCKLWIFG---NQLTSLPVLP----PGLQELSV 309
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 291 QGNDLYELPkGLLHRLEQLLVLDlsgNQLTSHHVDNSTfaglirLIVLNLSNNALTRIGSKTfKELYFLQILDMRNNSIG 370
Cdd:PRK15387 310 SDNQLASLP-ALPSELCKLWAYN---NQLTSLPTLPSG------LQELSVSDNQLASLPTLP-SELYKLWAYNNRLTSLP 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 371 HIEEGaflplynLHTLNLAENRLHTLDNRIFNglyvLTKLTLNNNLVSIVESQAfrncSDLKELDLSSNQLTEVPEAVQD 450
Cdd:PRK15387 379 ALPSG-------LKELIVSGNRLTSLPVLPSE----LKELMVSGNRLTSLPMLP----SGLLSLSVYRNQLTRLPESLIH 443
|
250 260 270
....*....|....*....|....*....|
gi 17136634 451 LSMLKTLDLGENQISEFKNNTFRNLNQLTG 480
Cdd:PRK15387 444 LSSETTVNLEGNPLSERTLQALREITSAPG 473
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
419-515 |
2.05e-04 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 43.60 E-value: 2.05e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 419 IVESQAFRNCSDLKELDLSSNQLTEVPEAVQDLSMLKTLDLGENQISEFKNntFRNLNQLTGLRLIDNRIGNITVGMFQD 498
Cdd:pfam14580 9 IEQSAQYTNPVRERELDLRGYKIPIIENLGATLDQFDTIDFSDNEIRKLDG--FPLLRRLKTLLLNNNRICRIGEGLGEA 86
|
90
....*....|....*..
gi 17136634 499 LPRLSVLNLAKNRIQSI 515
Cdd:pfam14580 87 LPNLTELILTNNNLQEL 103
|
|
| LRR_8 |
pfam13855 |
Leucine rich repeat; |
866-920 |
5.79e-04 |
|
Leucine rich repeat;
Pssm-ID: 404697 [Multi-domain] Cd Length: 61 Bit Score: 39.43 E-value: 5.79e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 17136634 866 LRELYLHNNMLTHISNATFEPLVSLEVLRLDNNRLSSLP--HLQYRHSLQGLTLGRN 920
Cdd:pfam13855 3 LRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSpgAFSGLPSLRYLDLSGN 59
|
|
| LRR_9 |
pfam14580 |
Leucine-rich repeat; |
214-313 |
7.71e-04 |
|
Leucine-rich repeat;
Pssm-ID: 405295 [Multi-domain] Cd Length: 175 Bit Score: 42.06 E-value: 7.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 214 TLDVSFNELRSLPdawGASRLRRLQTLSLQHNNISTLAPNALAGLSSLRVLNISYNHLVSLPS-EAFAGNKELRELHLQG 292
Cdd:pfam14580 46 TIDFSDNEIRKLD---GFPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQELGDlDPLASLKKLTFLSLLR 122
|
90 100
....*....|....*....|....
gi 17136634 293 NDLYELPK---GLLHRLEQLLVLD 313
Cdd:pfam14580 123 NPVTNKPHyrlYVIYKVPQLRLLD 146
|
|
| PLN03150 |
PLN03150 |
hypothetical protein; Provisional |
165-258 |
1.34e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 178695 [Multi-domain] Cd Length: 623 Bit Score: 43.27 E-value: 1.34e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 165 WCSMPSLQLLNLTQNRIRsaeflgfseklcagSALSNANGAVSGgseLQTLDVSFNELR-SLPDAWGasRLRRLQTLSLQ 243
Cdd:PLN03150 438 ISKLRHLQSINLSGNSIR--------------GNIPPSLGSITS---LEVLDLSYNSFNgSIPESLG--QLTSLRILNLN 498
|
90
....*....|....*
gi 17136634 244 HNNISTLAPNALAGL 258
Cdd:PLN03150 499 GNSLSGRVPAALGGR 513
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
434-656 |
1.59e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 41.70 E-value: 1.59e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 434 LDLSSNQLTEVPeavqDLSM---LKTLDLGENQISEFKNntFRNLNQLTGLRLIDNRIGNITvgMFQDLPRLSVLNLAKN 510
Cdd:cd21340 7 LYLNDKNITKID----NLSLcknLKVLYLYDNKITKIEN--LEFLTNLTHLYLQNNQIEKIE--NLENLVNLKKLYLGGN 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 511 RIQSIErgAFDKNTEIEAIRLDKNfltdingifatlasllwlNLSENHLVWFDYAfipsnlkwldihgnYIEALGNyykl 590
Cdd:cd21340 79 RISVVE--GLENLTNLEELHIENQ------------------RLPPGEKLTFDPR--------------SLAALSN---- 120
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17136634 591 qeeiRVTTLDASHNRITEIGAMSVPNSIELLFINNNIIGQIQ--ANTFVDKTRLARVDLYANVLSKIS 656
Cdd:cd21340 121 ----SLRVLNISGNNIDSLEPLAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVCKKP 184
|
|
| LRR_4 |
pfam12799 |
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ... |
236-273 |
3.72e-03 |
|
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.
Pssm-ID: 463713 [Multi-domain] Cd Length: 44 Bit Score: 36.45 E-value: 3.72e-03
10 20 30
....*....|....*....|....*....|....*...
gi 17136634 236 RLQTLSLQHNNISTLAPnaLAGLSSLRVLNISYNHLVS 273
Cdd:pfam12799 2 NLEVLDLSNNQITDIPP--LAKLPNLETLDLSGNNKIT 37
|
|
| PPP1R42 |
cd21340 |
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ... |
797-881 |
5.25e-03 |
|
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.
Pssm-ID: 411060 [Multi-domain] Cd Length: 220 Bit Score: 40.15 E-value: 5.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 797 LYLDGNNMPELEvgHLTGRRNLRALY----------------------------LNAS--NLMTLQngSLAQLVNLRVLH 846
Cdd:cd21340 73 LYLGGNRISVVE--GLENLTNLEELHienqrlppgekltfdprslaalsnslrvLNISgnNIDSLE--PLAPLRNLEQLD 148
|
90 100 110
....*....|....*....|....*....|....*..
gi 17136634 847 LENNKLTALEGTE--FRSLGLLRELYLHNNMLTHISN 881
Cdd:cd21340 149 ASNNQISDLEELLdlLSSWPSLRELDLTGNPVCKKPK 185
|
|
| LRR_5 |
pfam13306 |
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich ... |
407-587 |
5.32e-03 |
|
BspA type Leucine rich repeat region (6 copies); This family includes a number of leucine rich repeats. This family contains a large number of BSPA-like surface antigens from Trichomonas vaginalis.
Pssm-ID: 463839 [Multi-domain] Cd Length: 127 Bit Score: 38.29 E-value: 5.32e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 407 LTKLTLNNNLVSIvESQAFRNCSDLKELDLSSNqltevpeavqdlsmlktldlgenqISEFKNNTFRNLNqltglrlidn 486
Cdd:pfam13306 13 LTSITIPSSLTSI-GEYAFSNCTSLKSITLPSS------------------------LTSIGSYAFYNCS---------- 57
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 487 rIGNITvgmfqdLPrlsvlnlakNRIQSIERGAFDKNTEIEAIRLDKNfLTDINgifatlasllwlnlsenhlvwfDYAF 566
Cdd:pfam13306 58 -LTSIT------IP---------SSLTSIGEYAFSNCSNLKSITLPSN-LTSIG----------------------SYAF 98
|
170 180
....*....|....*....|.
gi 17136634 567 IPSNLKWLDIHGNyIEALGNY 587
Cdd:pfam13306 99 SNCSLKSITIPSS-VTTIGSY 118
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
115-310 |
8.45e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.16 E-value: 8.45e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 115 SLKRLTLeSHNAVWGPGktLELHGQSFQGLKELSELHLGDNNIRQlpEGVWCSMPSLQ------LLNLTQNRIRSAEFLG 188
Cdd:COG5238 265 TVETLYL-SGNQIGAEG--AIALAKALQGNTTLTSLDLSVNRIGD--EGAIALAEGLQgnktlhTLNLAYNGIGAQGAIA 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 189 FSEKLCAGSALSnangavsggselqTLDVSFNELrslpDAWGASRLrrlqtlslqhnnistlaPNALAGLSSLRVLNISY 268
Cdd:COG5238 340 LAKALQENTTLH-------------SLDLSDNQI----GDEGAIAL-----------------AKYLEGNTTLRELNLGK 385
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 17136634 269 NHLVSLPSEAFAGNKELRELHLQGNDLYELPKGLLHRLEQLL 310
Cdd:COG5238 386 NNIGKQGAEALIDALQTNRLHTLILDGNLIGAEAQQRLEQLL 427
|
|
| RNA1 |
COG5238 |
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ... |
314-629 |
8.75e-03 |
|
Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport [Translation, ribosomal structure and biogenesis];
Pssm-ID: 444072 [Multi-domain] Cd Length: 434 Bit Score: 40.16 E-value: 8.75e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 314 LSGNQLTSHHVDNSTFAGLIRLIvlNLSNNALTRIGSKTF-KELYFLQILDMrnnsighieEGAFLPLYNLHTLNLAENR 392
Cdd:COG5238 16 LSANPATTEQSELTKRATIVNLR--SYHLHGGAILLARYLqSRSSITQYLRF---------EGQGDPGLNPVALEKAAEA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 393 LHTLDNRIFnglyvltklTLNNNLVSIVES--QAFRNCSDLKELDLSSNQLTE---VPEAVQD-LSMLKTLDLGENQISE 466
Cdd:COG5238 85 FPTQLLVVD---------WEGAEEVSPVALaeTATAVATPPPDLRRIMAKTLEdslILYLALPrRINLIQVLKDPLGGNA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 467 FKNNTFRNLNQLTGLrlidnrignITVGMFQDLPRLSVLNLAKNRIQS--IER--GAFDKNTEIEAIRLDKNFLTDINgi 542
Cdd:COG5238 156 VHLLGLAARLGLLAA---------ISMAKALQNNSVETVYLGCNQIGDegIEElaEALTQNTTVTTLWLKRNPIGDEG-- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17136634 543 fatlASLLWLNLSENHlvwfdyafipsNLKWLDIHGNYI-----EALGNYykLQEEIRVTTLDASHNRITEIGAMSVPN- 616
Cdd:COG5238 225 ----AEILAEALKGNK-----------SLTTLDLSNNQIgdegvIALAEA--LKNNTTVETLYLSGNQIGAEGAIALAKa 287
|
330
....*....|....*...
gi 17136634 617 -----SIELLFINNNIIG 629
Cdd:COG5238 288 lqgntTLTSLDLSVNRIG 305
|
|
| |
