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Conserved domains on  [gi|17137310|ref|NP_477221|]
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congested-like trachea, isoform A [Drosophila melanogaster]

Protein Classification

solute carrier family 25 protein( domain architecture ID 10445172)

solute carrier 25 family (SLC25) protein which transfers molecules across the membranes of organelles, usually mitochondria

Gene Ontology:  GO:0016020|GO:1990542
TCDB:  2.A.29

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
12-107 2.99e-25

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 96.57  E-value: 2.99e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310    12 KANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEqplYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIF 91
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78
                          90
                  ....*....|....*.
gi 17137310    92 AMCFAGYALGKRLQQR 107
Cdd:pfam00153  79 AIYFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
112-202 7.66e-23

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 90.41  E-value: 7.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   112 KLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQqGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGL 191
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|.
gi 17137310   192 YFLVYEALQDV 202
Cdd:pfam00153  81 YFGTYETLKRL 91
Mito_carr pfam00153
Mitochondrial carrier protein;
210-299 1.75e-21

Mitochondrial carrier protein;


:

Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.94  E-value: 1.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   210 GQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPE--GTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAA 287
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|..
gi 17137310   288 CFFGIELANKFF 299
Cdd:pfam00153  81 YFGTYETLKRLL 92
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
12-107 2.99e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 96.57  E-value: 2.99e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310    12 KANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEqplYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIF 91
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78
                          90
                  ....*....|....*.
gi 17137310    92 AMCFAGYALGKRLQQR 107
Cdd:pfam00153  79 AIYFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
112-202 7.66e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 90.41  E-value: 7.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   112 KLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQqGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGL 191
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|.
gi 17137310   192 YFLVYEALQDV 202
Cdd:pfam00153  81 YFGTYETLKRL 91
Mito_carr pfam00153
Mitochondrial carrier protein;
210-299 1.75e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.94  E-value: 1.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   210 GQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPE--GTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAA 287
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|..
gi 17137310   288 CFFGIELANKFF 299
Cdd:pfam00153  81 YFGTYETLKRLL 92
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
10-282 4.01e-17

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 79.81  E-value: 4.01e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   10 ERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQT---MPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTG 86
Cdd:PTZ00169   2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTqdsIPEIKSGKVPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   87 VAPIFAMCFAGYALGKRLQQRgEDAKLTYPQIFVA----GSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCA 162
Cdd:PTZ00169  82 YFPTQAFNFAFKDYFKNMFPK-YNQKTDFWKFFGVnilsGGLAGASSLLIVYPLDFARTRLASDIGKGGDREFTGLFDCL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310  163 GKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYealqDVAKS---KSETGQ-------ISTASTIFAGgvagmaywILG 232
Cdd:PTZ00169 161 MKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLY----DSAKAllfGNDKNTnilykwaVAQTVTILAG--------LIS 228
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 17137310  233 MPADVLKSRL------QSAPEGTYKhGIRSVFKDLIVKDGPLALYRGVTPIMLRAF 282
Cdd:PTZ00169 229 YPFDTVRRRMmmmsgrKAKSEIQYT-GTLDCWKKILKNEGLGGFFKGAWANVLRGA 283
 
Name Accession Description Interval E-value
Mito_carr pfam00153
Mitochondrial carrier protein;
12-107 2.99e-25

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 96.57  E-value: 2.99e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310    12 KANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEqplYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIF 91
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGSGKSK---GRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAA 78
                          90
                  ....*....|....*.
gi 17137310    92 AMCFAGYALGKRLQQR 107
Cdd:pfam00153  79 AIYFGTYETLKRLLLK 94
Mito_carr pfam00153
Mitochondrial carrier protein;
112-202 7.66e-23

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 90.41  E-value: 7.66e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   112 KLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQqGQGGERKYNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGL 191
Cdd:pfam00153   2 ELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQ-GGSGKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|.
gi 17137310   192 YFLVYEALQDV 202
Cdd:pfam00153  81 YFGTYETLKRL 91
Mito_carr pfam00153
Mitochondrial carrier protein;
210-299 1.75e-21

Mitochondrial carrier protein;


Pssm-ID: 395101 [Multi-domain]  Cd Length: 96  Bit Score: 86.94  E-value: 1.75e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   210 GQISTASTIFAGGVAGMAYWILGMPADVLKSRLQSAPE--GTYKHGIRSVFKDLIVKDGPLALYRGVTPIMLRAFPANAA 287
Cdd:pfam00153   1 SELSFLASLLAGGIAGAIAVTVTYPLDVVKTRLQVQGGsgKSKGRGILDCFKKIYKEEGIRGLYKGLLPNLLRVAPAAAI 80
                          90
                  ....*....|..
gi 17137310   288 CFFGIELANKFF 299
Cdd:pfam00153  81 YFGTYETLKRLL 92
PTZ00169 PTZ00169
ADP/ATP transporter on adenylate translocase; Provisional
10-282 4.01e-17

ADP/ATP transporter on adenylate translocase; Provisional


Pssm-ID: 240302 [Multi-domain]  Cd Length: 300  Bit Score: 79.81  E-value: 4.01e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   10 ERKANPVKSFLTGGFGGICNVLSGHPLDTIKVRLQT---MPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTG 86
Cdd:PTZ00169   2 DKKTNFATDFLMGGISAAISKTAVAPIERVKMLIQTqdsIPEIKSGKVPRYSGIVNCFRRVSKEQGVLSLWRGNTANVIR 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   87 VAPIFAMCFAGYALGKRLQQRgEDAKLTYPQIFVA----GSFSGLFSTLIMAPGERIKVLLQTQQGQGGERKYNGMIDCA 162
Cdd:PTZ00169  82 YFPTQAFNFAFKDYFKNMFPK-YNQKTDFWKFFGVnilsGGLAGASSLLIVYPLDFARTRLASDIGKGGDREFTGLFDCL 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310  163 GKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYealqDVAKS---KSETGQ-------ISTASTIFAGgvagmaywILG 232
Cdd:PTZ00169 161 MKISKQTGFLSLYQGFGVSVQGIIVYRGAYFGLY----DSAKAllfGNDKNTnilykwaVAQTVTILAG--------LIS 228
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 17137310  233 MPADVLKSRL------QSAPEGTYKhGIRSVFKDLIVKDGPLALYRGVTPIMLRAF 282
Cdd:PTZ00169 229 YPFDTVRRRMmmmsgrKAKSEIQYT-GTLDCWKKILKNEGLGGFFKGAWANVLRGA 283
PTZ00168 PTZ00168
mitochondrial carrier protein; Provisional
17-273 6.49e-09

mitochondrial carrier protein; Provisional


Pssm-ID: 185494 [Multi-domain]  Cd Length: 259  Bit Score: 55.70  E-value: 6.49e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   17 KSFLTGGFGGICNVLSGHPLDTIKVRLQtmprpapgeqplyrgtfdcAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMCFA 96
Cdd:PTZ00168   5 HNLVTGALSGVIVDAVLYPIDSIKTNIQ-------------------AKKSFSFSDIKKLYSGILPTLVGTVPASAFFYC 65
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310   97 GYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKvllQTQQGQGGERKYNGMIDCAgklYKEGGLRSVFK 176
Cdd:PTZ00168  66 FYELSKKLLTEYRENISKTNLYLISTSIAEITACIVRLPFEIVK---QNMQVSGNISVLKTIYEIT---QREGLPSFLGK 139
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17137310  177 GSCATMLRDLPANGLYFLVYEALQDvaKSKSETGQIS----TASTIFAGGVAGMAYWILGMPADVLKSRlqsapEGTYKH 252
Cdd:PTZ00168 140 SYFVMIVREIPFDCIQYFLWETLKE--KAKKDFGKFSkkypSITSAICGGLAGGIAGFLTTPVDVIKSR-----QIIYGK 212
                        250       260
                 ....*....|....*....|.
gi 17137310  253 GIRSVFKDlIVKDGPLALYRG 273
Cdd:PTZ00168 213 SYIETVTE-IAEEGYLTFYKG 232
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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