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Conserved domains on  [gi|392885394|ref|NP_491394|]
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Collagen triple helix repeat protein [Caenorhabditis elegans]

Protein Classification

collagen-like domain-containing protein( domain architecture ID 1903237)

collagen-like domain-containing protein such as collagens, which are extracellular structural proteins involved in formation of connective tissue structure

PubMed:  21421911|15837519

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 85-240 3.70e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 50.67  E-value: 3.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394  85 DGIPGEPGVNGTNGFSGISVLVANGCIQCHIGKPGPRGKRGKRGKKGKDGKNGISVKAVIGLPGPTGEVGWQgypgfpgp 164
Cdd:NF038329 179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQ-------- 250

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392885394 165 VGPVGPPGNNKNRYIGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRTGATGHPGHTGRPGRDG 240
Cdd:NF038329 251 GPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDG 326
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 85-240 3.70e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 50.67  E-value: 3.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394  85 DGIPGEPGVNGTNGFSGISVLVANGCIQCHIGKPGPRGKRGKRGKKGKDGKNGISVKAVIGLPGPTGEVGWQgypgfpgp 164
Cdd:NF038329 179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQ-------- 250

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392885394 165 VGPVGPPGNNKNRYIGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRTGATGHPGHTGRPGRDG 240
Cdd:NF038329 251 GPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDG 326
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 180-237 2.99e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 2.99e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 392885394  180 GLPGPRGRAGRKGYQGAQGNAGFiynTGIIGPSGRSGKNGLNGRTGATGHPGHTGRPG 237
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGP---PGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 145-241 3.96e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 41.43  E-value: 3.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394 145 GLPGPTGEVGWQGYPGFPGPVGPVgppgnnknryiGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRT 224
Cdd:NF038329 150 GPPGPQGERGEKGPAGPQGEAGPQ-----------GPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEA 218

                         90
                 ....*....|....*..
gi 392885394 225 GATGHPGHTGRPGRDGN 241
Cdd:NF038329 219 GPAGEDGPAGPAGDGQQ 235
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 145-240 5.79e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.58  E-value: 5.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394 145 GLPGPTGEvgwqgypgfpgpvgpVGPPgnnknryiGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRT 224
Cdd:NF038329 120 GEPGPAGP---------------AGPA--------GEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPA 176

                         90
                 ....*....|....*.
gi 392885394 225 GATGHPGHTGRPGRDG 240
Cdd:NF038329 177 GKDGEAGAKGPAGEKG 192
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 85-240 3.70e-07

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 50.67  E-value: 3.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394  85 DGIPGEPGVNGTNGFSGISVLVANGCIQCHIGKPGPRGKRGKRGKKGKDGKNGISVKAVIGLPGPTGEVGWQgypgfpgp 164
Cdd:NF038329 179 DGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQ-------- 250

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 392885394 165 VGPVGPPGNNKNRYIGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRTGATGHPGHTGRPGRDG 240
Cdd:NF038329 251 GPDGPAGKDGPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDG 326
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 180-237 2.99e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 2.99e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 392885394  180 GLPGPRGRAGRKGYQGAQGNAGFiynTGIIGPSGRSGKNGLNGRTGATGHPGHTGRPG 237
Cdd:pfam01391   1 GPPGPPGPPGPPGPPGPPGPPGP---PGPPGPPGEPGPPGPPGPPGPPGPPGAPGAPG 55
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 145-241 3.96e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 41.43  E-value: 3.96e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394 145 GLPGPTGEVGWQGYPGFPGPVGPVgppgnnknryiGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRT 224
Cdd:NF038329 150 GPPGPQGERGEKGPAGPQGEAGPQ-----------GPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEA 218

                         90
                 ....*....|....*..
gi 392885394 225 GATGHPGHTGRPGRDGN 241
Cdd:NF038329 219 GPAGEDGPAGPAGDGQQ 235
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 145-240 5.79e-03

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 37.58  E-value: 5.79e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 392885394 145 GLPGPTGEvgwqgypgfpgpvgpVGPPgnnknryiGLPGPRGRAGRKGYQGAQGNAGFIYNTGIIGPSGRSGKNGLNGRT 224
Cdd:NF038329 120 GEPGPAGP---------------AGPA--------GEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPA 176

                         90
                 ....*....|....*.
gi 392885394 225 GATGHPGHTGRPGRDG 240
Cdd:NF038329 177 GKDGEAGAKGPAGEKG 192
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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