|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
42-294 |
1.13e-101 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
:
Pssm-ID: 214532 Cd Length: 238 Bit Score: 326.62 E-value: 1.13e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 42 SESERGLFPNIFNLATNSLITATDTCGQYTAEEYCKLVEHvllrkttNTQSPQCDICDANNVHKRHPIEYAIDGT----R 117
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLVGH-------TEQGKKCDYCDARNPRRSHPAENLTDGNnpnnP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 118 RWWQSPSLANGLrfEKVNITIDLRQEYQVAYIILKMGnSPRPGTWVLEKSLDGEYYEPWQYYAmqdAECMRQFGIPATTG 197
Cdd:smart00136 74 TWWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 198 VPRFqKEDEVHCTSEYSKITPLENGEIHTSLVNGRPGAEN--TSLELQKFTRARFVRLRLISPRTLNADLMiinkksdSL 275
Cdd:smart00136 148 ITKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDfdNSPVLQEWVTATNIRVRLTRLRTLGDELM-------DD 219
|
250
....*....|....*....
gi 25145020 276 DKSVTMRYFYSISDISIGG 294
Cdd:smart00136 220 RPEVTRRYYYAISDIAVGG 238
|
|
| LamB |
smart00281 |
Laminin B domain; |
583-711 |
1.39e-49 |
|
Laminin B domain;
:
Pssm-ID: 214597 Cd Length: 127 Bit Score: 172.83 E-value: 1.39e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 583 DRSLYYWKAPDSFKGNMLNSYGGYLHYDVYYVPTEQGATVFVADVAIEGNGIKIEYHSRIEFLPREKMTVAIPMSELSGW 662
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVEVRFREENWQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 663 YNAEarSPVDKADMMRALANVDRFTVRATYHQPQLQSSIFGLSLDTAVP 711
Cdd:smart00281 81 YYGG--RPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAVP 127
|
|
| LamB |
smart00281 |
Laminin B domain; |
1341-1478 |
3.59e-41 |
|
Laminin B domain;
:
Pssm-ID: 214597 Cd Length: 127 Bit Score: 148.56 E-value: 3.59e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1341 DATPLYWPLPSTMLGDRTASYNGFLRFKIWNEDNRRGLHGIRPDqqyfrhfpqVIIFGNN-RIELEHIPMEINDDGIY-K 1418
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPD---------VILEGNGlRISHPAEGPPLPDELTTvE 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1419 IRLHESEWRVRHspELTLTRKQMMVALQDTQGIYIRGTYTYpaRGDAINIQEVSLDVAVP 1478
Cdd:smart00281 72 VRFREENWQYYG--GRPVTREDLMMVLANLTAILIRATYSQ--QMAGSRLSDVSLEVAVP 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2471-2622 |
6.29e-30 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
:
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 117.52 E-value: 6.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2471 HLFRDGFANVSMSVSERTMSAITVIFNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVaELTSQNVYNDGK 2550
Cdd:cd00110 3 SFSGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSL-VLSSKTPLNDGQ 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2551 EHTVKAIRTGSEMYLQVDSdaDRFNTVITGENTALNIENENHYVAGVPMtlNKEVFGDINWNGFIGCILTVK 2622
Cdd:cd00110 82 WHSVSVERNGRSVTLSVDG--ERVVESGSPGGSALLNLDGPLYLGGLPE--DLKSPGLPVSPGFVGCIRDLK 149
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2919-3065 |
1.76e-28 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
:
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 113.28 E-value: 1.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2919 SSHSRINFEAPYPNITDFTVKLSLQTETSNGMIWAWANyKNYTRYIFLDIIDGFATLEVKGHKQPKILKHlGNRINDGQW 2998
Cdd:cd00110 5 SGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGS-QNGGDFLALELEDGRLVLRYDLGSGSLVLSS-KTPLNDGQW 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2999 HDITVEKKNRSLKLIIDSLGPVEMTDCPTPK--VMKKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMN 3065
Cdd:cd00110 83 HSVSVERNGRSVTLSVDGERVVESGSPGGSAllNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2655-2821 |
7.47e-25 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
:
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 102.88 E-value: 7.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2655 IGFPKPGYL-ITKGISIDNSSTFAFSFRTREENGTLVYQSSKlqkvskrdsedDGKGYIAFYLFRGYLVLHFgkdaSSRK 2733
Cdd:cd00110 2 VSFSGSSYVrLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQ-----------NGGDFLALELEDGRLVLRY----DLGS 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2734 EVVTFRSSHPYNDGQVHAVFMERNGKIISVKVDDKEIGDSQSLSDETSVgTTSGRLILGGFSDDLKPPNneIPITSFFIG 2813
Cdd:cd00110 67 GSLVLSSKTPLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALL-NLDGPLYLGGLPEDLKSPG--LPVSPGFVG 143
|
....*...
gi 25145020 2814 CISDVFLN 2821
Cdd:cd00110 144 CIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2285-2443 |
2.17e-14 |
|
Laminin G domain;
:
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 72.37 E-value: 2.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2285 TFHVSYRPLQqvSDAVILVSKTKGRrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHpinyVPSNDRvTWYHIDVLRI 2364
Cdd:smart00282 1 SISFSFRTTS--PNGLLLYAGSKGG----GDYLALELRDGRLVLRYDLGSGPARLTSDP----TPLNDG-QWHRVAVERN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2365 GNAVNLTV----ALKESYDGGFKPRGAPVSVFVGnskddnsifntipgettidvGTDETVASDIGLTTHKFSGIVGGLRI 2440
Cdd:smart00282 70 GRSVTLSVdggnRVSGESPGGLTILNLDGPLYLG--------------------GLPEDLKLPPLPVTPGFRGCIRNLKV 129
|
...
gi 25145020 2441 DEV 2443
Cdd:smart00282 130 NGK 132
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1086-1131 |
4.85e-14 |
|
Laminin-type epidermal growth factor-like domai;
:
Pssm-ID: 214543 Cd Length: 46 Bit Score: 68.49 E-value: 4.85e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGC 1131
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
988-1033 |
8.47e-14 |
|
Laminin-type epidermal growth factor-like domai;
:
Pssm-ID: 214543 Cd Length: 46 Bit Score: 67.72 E-value: 8.47e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 988 CDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDAGC 1033
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1646-1694 |
6.28e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 62.37 E-value: 6.28e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1646 PCDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERHAFINRVCTSC 1694
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
423-480 |
7.31e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 62.37 E-value: 7.31e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 25145020 423 CECDPVGSVSDACVRddqsaENGQkpgdCICKPGFGGRRCERCAPGYRNHPTCEPCPC 480
Cdd:pfam00053 1 CDCNPHGSLSDTCDP-----ETGQ----CLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| PRK03918 super family |
cl35229 |
DNA double-strand break repair ATPase Rad50; |
1831-2226 |
1.50e-11 |
|
DNA double-strand break repair ATPase Rad50;
The actual alignment was detected with superfamily member PRK03918:
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.48 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELL-KMVTAQKL-----NETIfEDLKNRIDVLEQWMNDYRETIYDVS 1904
Cdd:PRK03918 333 LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKaKKEELERLkkrltGLTP-EKLEKELEELEKAKEEIEEEISKIT 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1905 KK----DTADAERMSLV-----------VGKR----------INRYKEVSNEIEKLRVEAEDQiaysrnsIEKARSEelm 1959
Cdd:PRK03918 412 ARigelKKEIKELKKAIeelkkakgkcpVCGRelteehrkelLEEYTAELKRIEKELKEIEEK-------ERKLRKE--- 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1960 nmfedKEKINMTLAELPDLVEQCQnitlLYSQLID------EYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTEtenpL 2033
Cdd:PRK03918 482 -----LRELEKVLKKESELIKLKE----LAEQLKEleeklkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE----L 548
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2034 KASHAYENIVEALKnatEAVDSAAEASEAVSKMLGSEGSESGDANEESLRSqLEKLKNE-SSLSNVDnSNAVKIVEELKK 2112
Cdd:PRK03918 549 EKLEELKKKLAELE---KKLDELEEELAELLKELEELGFESVEELEERLKE-LEPFYNEyLELKDAE-KELEREEKELKK 623
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2113 EKKDLTDRLGHLNELKTSI---VKRLGVIKNEASswDDKHDRM----------HSILKNGAKTAHERSANVKKESEGIKT 2179
Cdd:PRK03918 624 LEEELDKAFEELAETEKRLeelRKELEELEKKYS--EEEYEELreeylelsreLAGLRAELEELEKRREEIKKTLEKLKE 701
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 25145020 2180 EVSAI---KAEVEKLmNSTSSGVQEDMEKIRASRTGMEYGAqkLTKVNKL 2226
Cdd:PRK03918 702 ELEERekaKKELEKL-EKALERVEELREKVKKYKALLKERA--LSKVGEI 748
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1181-1229 |
2.14e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.83 E-value: 2.14e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFFNFPTCEPCGC 1229
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
941-985 |
3.03e-11 |
|
Laminin-type epidermal growth factor-like domai;
:
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.40 E-value: 3.03e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 941 CGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH-GDVENGC 985
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYyGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
774-818 |
4.66e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.06 E-value: 4.66e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRGGE 818
Cdd:cd00055 2 CDCNGHgslSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1036-1083 |
2.48e-10 |
|
Laminin-type epidermal growth factor-like domai;
:
Pssm-ID: 214543 Cd Length: 46 Bit Score: 57.71 E-value: 2.48e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1036 CHCNIYGSIeDGKCDQTTGKCECRENVEGTMCEKCADGYFNItSGDGC 1083
Cdd:smart00180 1 CDCDPGGSA-SGTCDPDTGQCECKPNVTGRRCDRCAPGYYGD-GPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
296-343 |
2.19e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.36 E-value: 2.19e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 296 CICYGHAESCPS-DPVTGQfkCECRHNTCGESCNRCCPLFNQLPWKPGT 343
Cdd:cd00055 2 CDCNGHGSLSGQcDPGTGQ--CECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1539-1583 |
7.83e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.82 E-value: 7.83e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1539 PCSCHGH---SQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREGG 1583
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGG 47
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
889-943 |
2.84e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 49.27 E-value: 2.84e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 889 CTCNGNIDPmgIGNCDSETGKCLkCIGHTTGDSCESCKEHHWGNaqlHTCKPCGC 943
Cdd:pfam00053 1 CDCNPHGSL--SDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGL---PSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
477-526 |
5.51e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 48.50 E-value: 5.51e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 477 PCPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHLsASNPLGCQ 526
Cdd:cd00055 1 PCDCNGHGSLS-GQCDPGTgqCECKPNTTGRRCDRCAPGYYGL-PSQGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1227-1281 |
1.42e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 47.35 E-value: 1.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1227 CGCNAAGTDPLQCKDGQclcneiGECPCKKNVHGTKCDQCGEGTFSLDSSNLKGC 1281
Cdd:pfam00053 1 CDCNPHGSLSDTCDPET------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1133-1179 |
2.87e-04 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
:
Pssm-ID: 238012 Cd Length: 50 Bit Score: 40.80 E-value: 2.87e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1133 ECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAWDYHPL-NGCK 1179
Cdd:cd00055 3 DCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1590-1644 |
3.12e-04 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
:
Pssm-ID: 395007 Cd Length: 49 Bit Score: 40.80 E-value: 3.12e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCnSCKPGYTGQYCETCVAGYYGDPQHIGGTC 1644
Cdd:pfam00053 1 CDCNPH-GSLSDTC----DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
384-411 |
9.05e-04 |
|
Laminin-type epidermal growth factor-like domai;
:
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.22 E-value: 9.05e-04
10 20
....*....|....*....|....*...
gi 25145020 384 GGRClECAHNTEGFNCERCKDGYYRPSG 411
Cdd:smart00180 17 TGQC-ECKPNVTGRRCDRCAPGYYGDGP 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
42-294 |
1.13e-101 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
Pssm-ID: 214532 Cd Length: 238 Bit Score: 326.62 E-value: 1.13e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 42 SESERGLFPNIFNLATNSLITATDTCGQYTAEEYCKLVEHvllrkttNTQSPQCDICDANNVHKRHPIEYAIDGT----R 117
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLVGH-------TEQGKKCDYCDARNPRRSHPAENLTDGNnpnnP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 118 RWWQSPSLANGLrfEKVNITIDLRQEYQVAYIILKMGnSPRPGTWVLEKSLDGEYYEPWQYYAmqdAECMRQFGIPATTG 197
Cdd:smart00136 74 TWWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 198 VPRFqKEDEVHCTSEYSKITPLENGEIHTSLVNGRPGAEN--TSLELQKFTRARFVRLRLISPRTLNADLMiinkksdSL 275
Cdd:smart00136 148 ITKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDfdNSPVLQEWVTATNIRVRLTRLRTLGDELM-------DD 219
|
250
....*....|....*....
gi 25145020 276 DKSVTMRYFYSISDISIGG 294
Cdd:smart00136 220 RPEVTRRYYYAISDIAVGG 238
|
|
| Laminin_N |
pfam00055 |
Laminin N-terminal (Domain VI); |
48-294 |
2.79e-84 |
|
Laminin N-terminal (Domain VI);
Pssm-ID: 459653 Cd Length: 230 Bit Score: 276.39 E-value: 2.79e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 48 LFPNIFNLATNSLITATDTCGQYTAEEYCKLVEhvllrkttNTQSPQCDICDANNVHKRHPIEYAIDGT----RRWWQSP 123
Cdd:pfam00055 1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSG--------LEGGKKCFICDSRDPHNSHPPSNLTDSNngtnETWWQSE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 124 SLAngLRFEKVNITIDLRQEYQVAYIILKMGnSPRPGTWVLEKSLD-GEYYEPWQYYAmqdAECMRQFGIPatTGVPRFQ 202
Cdd:pfam00055 73 TGV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRP--SGPSRGI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 203 KEDEVHCTSEYSKITPLENGEIHTSLVNGRPGAEN--TSLELQKFTRARFVRLRLISPRTLNADLmiinkksdSLDKSVT 280
Cdd:pfam00055 145 KDDEVICTSEYSDISPLTGGEVIFSTLEGRPSANIfdYSPELQDWLTATNIRIRLLRLHTLGDEL--------LDDPSVL 216
|
250
....*....|....
gi 25145020 281 MRYFYSISDISIGG 294
Cdd:pfam00055 217 RKYYYAISDISVGG 230
|
|
| LamB |
smart00281 |
Laminin B domain; |
583-711 |
1.39e-49 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 172.83 E-value: 1.39e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 583 DRSLYYWKAPDSFKGNMLNSYGGYLHYDVYYVPTEQGATVFVADVAIEGNGIKIEYHSRIEFLPREKMTVAIPMSELSGW 662
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVEVRFREENWQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 663 YNAEarSPVDKADMMRALANVDRFTVRATYHQPQLQSSIFGLSLDTAVP 711
Cdd:smart00281 81 YYGG--RPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAVP 127
|
|
| LamB |
smart00281 |
Laminin B domain; |
1341-1478 |
3.59e-41 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 148.56 E-value: 3.59e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1341 DATPLYWPLPSTMLGDRTASYNGFLRFKIWNEDNRRGLHGIRPDqqyfrhfpqVIIFGNN-RIELEHIPMEINDDGIY-K 1418
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPD---------VILEGNGlRISHPAEGPPLPDELTTvE 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1419 IRLHESEWRVRHspELTLTRKQMMVALQDTQGIYIRGTYTYpaRGDAINIQEVSLDVAVP 1478
Cdd:smart00281 72 VRFREENWQYYG--GRPVTREDLMMVLANLTAILIRATYSQ--QMAGSRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
588-713 |
2.23e-37 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 138.17 E-value: 2.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 588 YWKAPDSFKGNMLNSYGGYLHYDVYYVPTEQGAT-VFVADVAIEGNGIKIEYHSRIEFLPR--EKMTVAIPMSElSGWYN 664
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSlNSEPDVILEGNGLRLSYSSPDQPPPDpgQEQTYSVRLHE-ENWRD 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 665 AEaRSPVDKADMMRALANVDRFTVRATYHQPQLQSSIFGLSLDTAVPAP 713
Cdd:pfam00052 80 SD-GAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAVPGG 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2471-2622 |
6.29e-30 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 117.52 E-value: 6.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2471 HLFRDGFANVSMSVSERTMSAITVIFNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVaELTSQNVYNDGK 2550
Cdd:cd00110 3 SFSGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSL-VLSSKTPLNDGQ 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2551 EHTVKAIRTGSEMYLQVDSdaDRFNTVITGENTALNIENENHYVAGVPMtlNKEVFGDINWNGFIGCILTVK 2622
Cdd:cd00110 82 WHSVSVERNGRSVTLSVDG--ERVVESGSPGGSALLNLDGPLYLGGLPE--DLKSPGLPVSPGFVGCIRDLK 149
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2919-3065 |
1.76e-28 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 113.28 E-value: 1.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2919 SSHSRINFEAPYPNITDFTVKLSLQTETSNGMIWAWANyKNYTRYIFLDIIDGFATLEVKGHKQPKILKHlGNRINDGQW 2998
Cdd:cd00110 5 SGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGS-QNGGDFLALELEDGRLVLRYDLGSGSLVLSS-KTPLNDGQW 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2999 HDITVEKKNRSLKLIIDSLGPVEMTDCPTPK--VMKKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMN 3065
Cdd:cd00110 83 HSVSVERNGRSVTLSVDGERVVESGSPGGSAllNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2937-3067 |
9.07e-28 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 110.51 E-value: 9.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2937 TVKLSLQTETSNGMIWAWANyKNYTRYIFLDIIDGFATLEVKGHKQPKILKHLGNRINDGQWHDITVEKKNRSLKLIIDS 3016
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGS-KGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSVDG 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 25145020 3017 LGPVEMTDCPTPKV--MKKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMNNR 3067
Cdd:smart00282 80 GNRVSGESPGGLTIlnLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
smart00282 |
Laminin G domain; |
2492-2622 |
1.25e-27 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 110.12 E-value: 1.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2492 ITVIFNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVAELTSQNVYNDGKEHTVKAIRTGSEMYLQVDsDA 2571
Cdd:smart00282 2 ISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSVD-GG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 25145020 2572 DRFNTVITGENTALNIeNENHYVAGVPMTLNKevFGDINWNGFIGCILTVK 2622
Cdd:smart00282 81 NRVSGESPGGLTILNL-DGPLYLGGLPEDLKL--PPLPVTPGFRGCIRNLK 128
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
1346-1480 |
2.08e-27 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 109.67 E-value: 2.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1346 YWPLPSTMLGDRTASYNGFLRFKIWNEDNRRGlhGIRPDQqyfrhfPQVIIFGNNrIELEHIPMEI-----NDDGIYKIR 1420
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSE------PDVILEGNG-LRLSYSSPDQpppdpGQEQTYSVR 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1421 LHESEWRvrHSPELTLTRKQMMVALQDTQGIYIRGTYTYPARGdaINIQEVSLDVAVPES 1480
Cdd:pfam00052 72 LHEENWR--DSDGAPVSREDFMMVLANLTAILIRATYSTGSGQ--VSLSNVSLDSAVPGG 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2655-2821 |
7.47e-25 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 102.88 E-value: 7.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2655 IGFPKPGYL-ITKGISIDNSSTFAFSFRTREENGTLVYQSSKlqkvskrdsedDGKGYIAFYLFRGYLVLHFgkdaSSRK 2733
Cdd:cd00110 2 VSFSGSSYVrLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQ-----------NGGDFLALELEDGRLVLRY----DLGS 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2734 EVVTFRSSHPYNDGQVHAVFMERNGKIISVKVDDKEIGDSQSLSDETSVgTTSGRLILGGFSDDLKPPNneIPITSFFIG 2813
Cdd:cd00110 67 GSLVLSSKTPLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALL-NLDGPLYLGGLPEDLKSPG--LPVSPGFVG 143
|
....*...
gi 25145020 2814 CISDVFLN 2821
Cdd:cd00110 144 CIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2675-2823 |
1.66e-24 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 101.26 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2675 TFAFSFRTREENGTLVYQSSKlqkvskrdsedDGKGYIAFYLFRGYLVLHFgkDASSRKEVVTFrSSHPYNDGQVHAVFM 2754
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSK-----------GGGDYLALELRDGRLVLRY--DLGSGPARLTS-DPTPLNDGQWHRVAV 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2755 ERNGKIISVKVDDKEIGDSQSLSDETSVGTTsGRLILGGFSDDLKPPNneIPITSFFIGCISDVFLNMK 2823
Cdd:smart00282 67 ERNGRSVTLSVDGGNRVSGESPGGLTILNLD-GPLYLGGLPEDLKLPP--LPVTPGFRGCIRNLKVNGK 132
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2680-2821 |
1.34e-20 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 89.79 E-value: 1.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2680 FRTREENGTLVYqssklqkvskrdSEDDGKGYIAFYLFRGYLVLHFgkDASSRkEVVTFRSSHPYNDGQVHAVFMERNGK 2759
Cdd:pfam02210 1 FRTRQPNGLLLY------------AGGGGSDFLALELVNGRLVLRY--DLGSG-PESLLSSGKNLNDGQWHSVRVERNGN 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2760 IISVKVDDKEIGdSQSLSDETSVGTTSGRLILGGFSDDLKPPNneIPITSFFIGCISDVFLN 2821
Cdd:pfam02210 66 TLTLSVDGQTVV-SSLPPGESLLLNLNGPLYLGGLPPLLLLPA--LPVRAGFVGCIRDVRVN 124
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2500-2618 |
8.40e-19 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 84.78 E-value: 8.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2500 SPNGLLYFRGSEaSGDFVAIYLNDGKVMFKINLGGGSVAELTSQNVYNDGKEHTVKAIRTGSEMYLQVDSdaDRFNTVIT 2579
Cdd:pfam02210 5 QPNGLLLYAGGG-GSDFLALELVNGRLVLRYDLGSGPESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDG--QTVVSSLP 81
|
90 100 110
....*....|....*....|....*....|....*....
gi 25145020 2580 GENTALNIENENHYVAGVPMTLNKEvfGDINWNGFIGCI 2618
Cdd:pfam02210 82 PGESLLLNLNGPLYLGGLPPLLLLP--ALPVRAGFVGCI 118
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2944-3067 |
2.06e-17 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 80.93 E-value: 2.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2944 TETSNGMIWAWANYKNytRYIFLDIIDGFATLEVKGHKQPKILKHLGNRINDGQWHDITVEKKNRSLKLIIDSLGPVEMT 3023
Cdd:pfam02210 3 TRQPNGLLLYAGGGGS--DFLALELVNGRLVLRYDLGSGPESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSSL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 25145020 3024 DCPTPKVM--KKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMNNR 3067
Cdd:pfam02210 81 PPGESLLLnlNGPLYLGGLPPLLLLPALPVRAGFVGCIRDVRVNGE 126
|
|
| LamG |
smart00282 |
Laminin G domain; |
2285-2443 |
2.17e-14 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 72.37 E-value: 2.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2285 TFHVSYRPLQqvSDAVILVSKTKGRrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHpinyVPSNDRvTWYHIDVLRI 2364
Cdd:smart00282 1 SISFSFRTTS--PNGLLLYAGSKGG----GDYLALELRDGRLVLRYDLGSGPARLTSDP----TPLNDG-QWHRVAVERN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2365 GNAVNLTV----ALKESYDGGFKPRGAPVSVFVGnskddnsifntipgettidvGTDETVASDIGLTTHKFSGIVGGLRI 2440
Cdd:smart00282 70 GRSVTLSVdggnRVSGESPGGLTILNLDGPLYLG--------------------GLPEDLKLPPLPVTPGFRGCIRNLKV 129
|
...
gi 25145020 2441 DEV 2443
Cdd:smart00282 130 NGK 132
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1086-1131 |
4.85e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 68.49 E-value: 4.85e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGC 1131
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1086-1134 |
8.11e-14 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 67.76 E-value: 8.11e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGCTEC 1134
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
988-1033 |
8.47e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 67.72 E-value: 8.47e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 988 CDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDAGC 1033
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1086-1130 |
1.96e-13 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 66.99 E-value: 1.96e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEG 1130
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
988-1036 |
1.53e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 64.30 E-value: 1.53e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 988 CDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDAGCQFC 1036
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
987-1034 |
2.46e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 63.53 E-value: 2.46e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 987 ACDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDA--GCQ 1034
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQggGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1646-1694 |
6.28e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 62.37 E-value: 6.28e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1646 PCDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERHAFINRVCTSC 1694
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
423-480 |
7.31e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 62.37 E-value: 7.31e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 25145020 423 CECDPVGSVSDACVRddqsaENGQkpgdCICKPGFGGRRCERCAPGYRNHPTCEPCPC 480
Cdd:pfam00053 1 CDCNPHGSLSDTCDP-----ETGQ----CLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1831-2226 |
1.50e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.48 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELL-KMVTAQKL-----NETIfEDLKNRIDVLEQWMNDYRETIYDVS 1904
Cdd:PRK03918 333 LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKaKKEELERLkkrltGLTP-EKLEKELEELEKAKEEIEEEISKIT 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1905 KK----DTADAERMSLV-----------VGKR----------INRYKEVSNEIEKLRVEAEDQiaysrnsIEKARSEelm 1959
Cdd:PRK03918 412 ARigelKKEIKELKKAIeelkkakgkcpVCGRelteehrkelLEEYTAELKRIEKELKEIEEK-------ERKLRKE--- 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1960 nmfedKEKINMTLAELPDLVEQCQnitlLYSQLID------EYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTEtenpL 2033
Cdd:PRK03918 482 -----LRELEKVLKKESELIKLKE----LAEQLKEleeklkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE----L 548
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2034 KASHAYENIVEALKnatEAVDSAAEASEAVSKMLGSEGSESGDANEESLRSqLEKLKNE-SSLSNVDnSNAVKIVEELKK 2112
Cdd:PRK03918 549 EKLEELKKKLAELE---KKLDELEEELAELLKELEELGFESVEELEERLKE-LEPFYNEyLELKDAE-KELEREEKELKK 623
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2113 EKKDLTDRLGHLNELKTSI---VKRLGVIKNEASswDDKHDRM----------HSILKNGAKTAHERSANVKKESEGIKT 2179
Cdd:PRK03918 624 LEEELDKAFEELAETEKRLeelRKELEELEKKYS--EEEYEELreeylelsreLAGLRAELEELEKRREEIKKTLEKLKE 701
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 25145020 2180 EVSAI---KAEVEKLmNSTSSGVQEDMEKIRASRTGMEYGAqkLTKVNKL 2226
Cdd:PRK03918 702 ELEERekaKKELEKL-EKALERVEELREKVKKYKALLKERA--LSKVGEI 748
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1181-1229 |
2.14e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.83 E-value: 2.14e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFFNFPTCEPCGC 1229
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
941-985 |
3.03e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.40 E-value: 3.03e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 941 CGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH-GDVENGC 985
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYyGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
774-818 |
4.66e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.06 E-value: 4.66e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRGGE 818
Cdd:cd00055 2 CDCNGHgslSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1647-1684 |
6.82e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 59.63 E-value: 6.82e-11
10 20 30
....*....|....*....|....*....|....*...
gi 25145020 1647 CDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERH 1684
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1647-1684 |
1.54e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 58.52 E-value: 1.54e-10
10 20 30
....*....|....*....|....*....|....*...
gi 25145020 1647 CDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERH 1684
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
940-978 |
1.98e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 58.13 E-value: 1.98e-10
10 20 30
....*....|....*....|....*....|....*....
gi 25145020 940 PCGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH 978
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1036-1083 |
2.48e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 57.71 E-value: 2.48e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1036 CHCNIYGSIeDGKCDQTTGKCECRENVEGTMCEKCADGYFNItSGDGC 1083
Cdd:smart00180 1 CDCDPGGSA-SGTCDPDTGQCECKPNVTGRRCDRCAPGYYGD-GPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
774-818 |
2.97e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.75 E-value: 2.97e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRGGE 818
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1036-1084 |
3.97e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.36 E-value: 3.97e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 1036 CHCNIYGSiEDGKCDQTTGKCECRENVEGTMCEKCADGYFNITS-GDGCE 1084
Cdd:cd00055 2 CDCNGHGS-LSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
423-474 |
1.02e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.21 E-value: 1.02e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 423 CECDPVGSVSDACVRDDqsaengqkpGDCICKPGFGGRRCERCAPGYRNHPT 474
Cdd:cd00055 2 CDCNGHGSLSGQCDPGT---------GQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1036-1083 |
1.65e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 55.82 E-value: 1.65e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 1036 CHCNIYGSIEDGkCDQTTGKCECRENVEGTMCEKCADGYFN--ITSGDGC 1083
Cdd:pfam00053 1 CDCNPHGSLSDT-CDPETGQCLCKPGVTGRHCDRCKPGYYGlpSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
423-475 |
2.37e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 55.01 E-value: 2.37e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 423 CECDPVGSVSDACVRDDqsaengqkpGDCICKPGFGGRRCERCAPGY--RNHPTC 475
Cdd:smart00180 1 CDCDPGGSASGTCDPDT---------GQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1181-1223 |
2.50e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 55.05 E-value: 2.50e-09
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFFNFPT 1223
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2273-2441 |
3.35e-09 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 58.20 E-value: 3.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2273 SYISPASPSPVNTFHVSYRPLQqvSDAVILVSKTKGRrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHPInyvpsND 2352
Cdd:cd00110 11 RLPTLPAPRTRLSISFSFRTTS--PNGLLLYAGSQNG----GDFLALELEDGRLVLRYDLGSGSLVLSSKTPL-----ND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2353 RvTWYHIDVLRIGNAVNLTV----ALKESYDGGFKPRGAPVSVFVGnskddnsifntipgettidvGTDETVASDIGLTT 2428
Cdd:cd00110 80 G-QWHSVSVERNGRSVTLSVdgerVVESGSPGGSALLNLDGPLYLG--------------------GLPEDLKSPGLPVS 138
|
170
....*....|...
gi 25145020 2429 HKFSGIVGGLRID 2441
Cdd:cd00110 139 PGFVGCIRDLKVN 151
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1849-2250 |
3.85e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.73 E-value: 3.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1849 EKRLNRAQQEHKKAEELLKMVTAQ-------------KLNETI--FEDLKNRIDVLEQWMNDYRETIYDVSKKDTADAER 1913
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEikkkekeleklnnKYNDLKkqKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1914 MSLVVgKRINRYKEVSNEIEKLrveaEDQiaysRNSIEKARSEELMNMFEDKEKINMTLAELPDLVEQCQNITllySQLI 1993
Cdd:TIGR04523 203 LSNLK-KKIQKNKSLESQISEL----KKQ----NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK---KQLS 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1994 DEYDEeyVQTAGRHAEKLEVQAQKIvdrfvdtRTETENpLKaSHAYENIVEALKNATEAVDSAAEASEavskmlgSEGSE 2073
Cdd:TIGR04523 271 EKQKE--LEQNNKKIKELEKQLNQL-------KSEISD-LN-NQKEQDWNKELKSELKNQEKKLEEIQ-------NQISQ 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2074 sgdaNEE---SLRSQLEKLKNESSLSNVDNSNAVKIVEE----LKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEASSWD 2146
Cdd:TIGR04523 333 ----NNKiisQLNEQISQLKKELTNSESENSEKQRELEEkqneIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2147 DKHDRMHSILKNGAKTAHE----RSANVKKESE--GIKTEVSAIKAEVEKLMNSTSSgVQEDMEKIRAS----RTGMEYG 2216
Cdd:TIGR04523 409 QKDEQIKKLQQEKELLEKEierlKETIIKNNSEikDLTNQDSVKELIIKNLDNTRES-LETQLKVLSRSinkiKQNLEQK 487
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 25145020 2217 AQKLT-KVNKLSTANQ------GRTDKMARNIAILKAKIEQ 2250
Cdd:TIGR04523 488 QKELKsKEKELKKLNEekkeleEKVKDLTKKISSLKEKIEK 528
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1181-1224 |
3.87e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.87e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFF--NFPTC 1224
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYgdGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
941-990 |
4.09e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 54.67 E-value: 4.09e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 25145020 941 CGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH-GDveNGCPACDC 990
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYyGL--PSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
296-343 |
2.19e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.36 E-value: 2.19e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 296 CICYGHAESCPS-DPVTGQfkCECRHNTCGESCNRCCPLFNQLPWKPGT 343
Cdd:cd00055 2 CDCNGHGSLSGQcDPGTGQ--CECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
774-816 |
2.44e-08 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 52.31 E-value: 2.44e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRG 816
Cdd:smart00180 1 CDCDPGgsaSGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1880-2161 |
2.80e-08 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 58.00 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1880 EDLKNRIDVLEQWMNDYRETIYDVSK--KDTAdAERMSLvvgkrINRYKEVSNEIEKLRvEAEDQIaysrnsIEKARseE 1957
Cdd:COG1340 11 EELEEKIEELREEIEELKEKRDELNEelKELA-EKRDEL-----NAQVKELREEAQELR-EKRDEL------NEKVK--E 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1958 LmnmfedKEKINMTLAELPDLVEQcqnitllysqlIDEYDEEYVQTAGRHA---------EKLEVQAQ----------KI 2018
Cdd:COG1340 76 L------KEERDELNEKLNELREE-----------LDELRKELAELNKAGGsidklrkeiERLEWRQQtevlspeeekEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2019 VDRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASEAVSKMlgseGSESGDANEE--SLRSQLEKLKNESSLS 2096
Cdd:COG1340 139 VEKIKELEKELEKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKEL----AEEAQELHEEmiELYKEADELRKEADEL 214
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 2097 NVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIK--NEASSWDDKHDRMHSILKNGAK 2161
Cdd:COG1340 215 HKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKreKEKEELEEKAEEIFEKLKKGEK 281
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1843-2205 |
6.68e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 6.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1843 ERGEYVEKRLNRAQQEHKKAEELLKMVTAqklneTIFEDLKNRIDVLEQWMNDYRETIYDVSKKdTADAERMSlvvgkRI 1922
Cdd:pfam05483 331 EEKEAQMEELNKAKAAHSFVVTEFEATTC-----SLEELLRTEQQRLEKNEDQLKIITMELQKK-SSELEEMT-----KF 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1923 NRYKEVsnEIEKLR-VEAEDQ-IAYSRNSIEK------ARSEELMNMFEDKEKinmtlaELPDLVEQCQNITL---LYSQ 1991
Cdd:pfam05483 400 KNNKEV--ELEELKkILAEDEkLLDEKKQFEKiaeelkGKEQELIFLLQAREK------EIHDLEIQLTAIKTseeHYLK 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1992 LIDEYDEEYVQTAGR------HAEKLEVQAQKIV----DRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASE 2061
Cdd:pfam05483 472 EVEDLKTELEKEKLKnieltaHCDKLLLENKELTqeasDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELE 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2062 AVSKMLGSEGSESG---DANEESLRS-QLEKLKNESSLSNVDNS---------NAVKIVEELKKEKKDLTDRlghlnelK 2128
Cdd:pfam05483 552 SVREEFIQKGDEVKcklDKSEENARSiEYEVLKKEKQMKILENKcnnlkkqieNKNKNIEELHQENKALKKK-------G 624
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2129 TSIVKRLGVikneassWDDKHDRMHSILKNGAKTAHERSANVKKESEGIKTEVSAIKAEVEKLMNSTSSGV--QEDMEK 2205
Cdd:pfam05483 625 SAENKQLNA-------YEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVklQKEIDK 696
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1539-1583 |
7.83e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.82 E-value: 7.83e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1539 PCSCHGH---SQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREGG 1583
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGG 47
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
889-943 |
2.84e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 49.27 E-value: 2.84e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 889 CTCNGNIDPmgIGNCDSETGKCLkCIGHTTGDSCESCKEHHWGNaqlHTCKPCGC 943
Cdd:pfam00053 1 CDCNPHGSL--SDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGL---PSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
477-526 |
5.51e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 48.50 E-value: 5.51e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 477 PCPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHLsASNPLGCQ 526
Cdd:cd00055 1 PCDCNGHGSLS-GQCDPGTgqCECKPNTTGRRCDRCAPGYYGL-PSQGGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1227-1281 |
1.42e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 47.35 E-value: 1.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1227 CGCNAAGTDPLQCKDGQclcneiGECPCKKNVHGTKCDQCGEGTFSLDSSNLKGC 1281
Cdd:pfam00053 1 CDCNPHGSLSDTCDPET------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
478-525 |
1.55e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 47.35 E-value: 1.55e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 478 CPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHLSASNPLGC 525
Cdd:pfam00053 1 CDCNPHGSLS-DTCDPETgqCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
889-939 |
1.97e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 46.96 E-value: 1.97e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 889 CTCNGNIDPMGigNCDSETGKCLkCIGHTTGDSCESCKEHHWGNA-QLHTCK 939
Cdd:cd00055 2 CDCNGHGSLSG--QCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPsQGGGCQ 50
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1540-1582 |
2.37e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 46.54 E-value: 2.37e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1540 CSCHG---HSQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREG 1582
Cdd:smart00180 1 CDCDPggsASGTCDPDTGQC-ECKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1540-1583 |
7.09e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 45.42 E-value: 7.09e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 25145020 1540 CSCHGH---SQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREGG 1583
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1226-1282 |
1.61e-05 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 44.27 E-value: 1.61e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 1226 PCGCNAAGTDPLQCKDGQclcneiGECPCKKNVHGTKCDQCGEGTFSlDSSNLKGCT 1282
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGT------GQCECKPNTTGRRCDRCAPGYYG-LPSQGGGCQ 50
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
478-525 |
2.43e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.84 E-value: 2.43e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 478 CPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHlsaSNPLGC 525
Cdd:smart00180 1 CDCDPGGSAS-GTCDPDTgqCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
889-932 |
2.67e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.76 E-value: 2.67e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 889 CTCN--GNIDPmgigNCDSETGKCLkCIGHTTGDSCESCKEHHWGN 932
Cdd:smart00180 1 CDCDpgGSASG----TCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1133-1179 |
2.87e-04 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 40.80 E-value: 2.87e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1133 ECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAWDYHPL-NGCK 1179
Cdd:cd00055 3 DCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1590-1644 |
3.12e-04 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 40.80 E-value: 3.12e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCnSCKPGYTGQYCETCVAGYYGDPQHIGGTC 1644
Cdd:pfam00053 1 CDCNPH-GSLSDTC----DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
296-339 |
3.52e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.37 E-value: 3.52e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 25145020 296 CICY--GHA-ESCpsDPVTGQfkCECRHNTCGESCNRCCPLFNQLPW 339
Cdd:smart00180 1 CDCDpgGSAsGTC--DPDTGQ--CECKPNVTGRRCDRCAPGYYGDGP 43
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
296-342 |
4.48e-04 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 40.41 E-value: 4.48e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 296 CICYGHAESCPS-DPVTGQfkCECRHNTCGESCNRCCPLFNQLPWKPG 342
Cdd:pfam00053 1 CDCNPHGSLSDTcDPETGQ--CLCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1227-1271 |
5.21e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.99 E-value: 5.21e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 25145020 1227 CGCNAAGTDPLQCKdgqclcNEIGECPCKKNVHGTKCDQCGEGTF 1271
Cdd:smart00180 1 CDCDPGGSASGTCD------PDTGQCECKPNVTGRRCDRCAPGYY 39
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2291-2372 |
5.77e-04 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 42.41 E-value: 5.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2291 RPLQqvSDAVILVSKTKGrrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHpinyVPSNDRvTWYHIDVLRIGNAVNL 2370
Cdd:pfam02210 2 RTRQ--PNGLLLYAGGGG-----SDFLALELVNGRLVLRYDLGSGPESLLSSG----KNLNDG-QWHSVRVERNGNTLTL 69
|
..
gi 25145020 2371 TV 2372
Cdd:pfam02210 70 SV 71
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1590-1637 |
6.10e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.99 E-value: 6.10e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCNsCKPGYTGQYCETCVAGYYGDP 1637
Cdd:smart00180 1 CDCDPG-GSASGTC----DPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1590-1642 |
6.68e-04 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 40.03 E-value: 6.68e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCnSCKPGYTGQYCETCVAGYYGDPQHIGG 1642
Cdd:cd00055 2 CDCNGH-GSLSGQC----DPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
384-411 |
9.05e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.22 E-value: 9.05e-04
10 20
....*....|....*....|....*...
gi 25145020 384 GGRClECAHNTEGFNCERCKDGYYRPSG 411
Cdd:smart00180 17 TGQC-ECKPNVTGRRCDRCAPGYYGDGP 43
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1136-1178 |
1.29e-03 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 38.83 E-value: 1.29e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1136 PCPAPGQV---CDPIDGSCVCPPNTVGEMCENCTTNAWDYHPlNGC 1178
Cdd:smart00180 2 DCDPGGSAsgtCDPDTGQCECKPNVTGRRCDRCAPGYYGDGP-PGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
384-408 |
1.40e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.87 E-value: 1.40e-03
10 20
....*....|....*....|....*
gi 25145020 384 GGRCLeCAHNTEGFNCERCKDGYYR 408
Cdd:pfam00053 17 TGQCL-CKPGVTGRHCDRCKPGYYG 40
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1133-1178 |
1.76e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.49 E-value: 1.76e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1133 ECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAWDYHPLNGC 1178
Cdd:pfam00053 2 DCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
383-410 |
1.91e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 38.49 E-value: 1.91e-03
10 20
....*....|....*....|....*...
gi 25145020 383 GGGRClECAHNTEGFNCERCKDGYYRPS 410
Cdd:cd00055 17 GTGQC-ECKPNTTGRRCDRCAPGYYGLP 43
|
|
| BAR |
smart00721 |
BAR domain; |
1848-2058 |
1.95e-03 |
|
BAR domain;
Pssm-ID: 214787 [Multi-domain] Cd Length: 239 Bit Score: 42.76 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1848 VEKRLNRAQQehkKAEELLKMVTAQKLNEtIFEDLKNRIDVLEQWMND-YRETIYDVSKKDTADAE-----RMSLVVGKR 1921
Cdd:smart00721 2 FKKQFNRAKQ---KVGEKVGKAEKTKLDE-DFEELERRFDTTEAEIEKlQKDTKLYLQPNPAVRAKlasqkKLSKSLGEV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1922 INRYK-----EVSNEIEKLRV---EAEDQIAYSRNSIEKARSEELMNMfedkekINMTLAELPDLVEQcqnITLLYSQLI 1993
Cdd:smart00721 78 YEGGDdgeglGADSSYGKALDklgEALKKLLQVEESLSQVKRTFILPL------LNFLLGEFKEIKKA---RKKLERKLL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25145020 1994 DeYDeeYVQTAGRHAEKLEvqAQKIVDRFVDTRTETEnplKASHAYENIVEALKNATEA-VDSAAE 2058
Cdd:smart00721 149 D-YD--SARHKLKKAKKSK--EKKKDEKLAKAEEELR---KAKQEFEESNAQLVEELPQlVASRVD 206
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| LamNT |
smart00136 |
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related ... |
42-294 |
1.13e-101 |
|
Laminin N-terminal domain (domain VI); N-terminal domain of laminins and laminin-related protein such as Unc-6/ netrins.
Pssm-ID: 214532 Cd Length: 238 Bit Score: 326.62 E-value: 1.13e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 42 SESERGLFPNIFNLATNSLITATDTCGQYTAEEYCKLVEHvllrkttNTQSPQCDICDANNVHKRHPIEYAIDGT----R 117
Cdd:smart00136 1 AGRPRSCYPPFVNLAFGREVTATSTCGEPGPERYCKLVGH-------TEQGKKCDYCDARNPRRSHPAENLTDGNnpnnP 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 118 RWWQSPSLANGLrfEKVNITIDLRQEYQVAYIILKMGnSPRPGTWVLEKSLDGEYYEPWQYYAmqdAECMRQFGIPATTG 197
Cdd:smart00136 74 TWWQSEPLSNGP--QNVNLTLDLGKEFHVTYVILKFC-SPRPSLWILERSDFGKTWQPWQYFS---SDCRRTFGRPPRGP 147
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 198 VPRFqKEDEVHCTSEYSKITPLENGEIHTSLVNGRPGAEN--TSLELQKFTRARFVRLRLISPRTLNADLMiinkksdSL 275
Cdd:smart00136 148 ITKG-NEDEVICTSEYSDIVPLEGGEIAFSLLEGRPSATDfdNSPVLQEWVTATNIRVRLTRLRTLGDELM-------DD 219
|
250
....*....|....*....
gi 25145020 276 DKSVTMRYFYSISDISIGG 294
Cdd:smart00136 220 RPEVTRRYYYAISDIAVGG 238
|
|
| Laminin_N |
pfam00055 |
Laminin N-terminal (Domain VI); |
48-294 |
2.79e-84 |
|
Laminin N-terminal (Domain VI);
Pssm-ID: 459653 Cd Length: 230 Bit Score: 276.39 E-value: 2.79e-84
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 48 LFPNIFNLATNSLITATDTCGQYTAEEYCKLVEhvllrkttNTQSPQCDICDANNVHKRHPIEYAIDGT----RRWWQSP 123
Cdd:pfam00055 1 CYPAFGNLAFGREVSATSTCGLNGPERYCILSG--------LEGGKKCFICDSRDPHNSHPPSNLTDSNngtnETWWQSE 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 124 SLAngLRFEKVNITIDLRQEYQVAYIILKMGnSPRPGTWVLEKSLD-GEYYEPWQYYAmqdAECMRQFGIPatTGVPRFQ 202
Cdd:pfam00055 73 TGV--IQYENVNLTLDLGKEFHFTYLILKFK-SPRPAAMVLERSTDfGKTWQPYQYFA---SDCRRTFGRP--SGPSRGI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 203 KEDEVHCTSEYSKITPLENGEIHTSLVNGRPGAEN--TSLELQKFTRARFVRLRLISPRTLNADLmiinkksdSLDKSVT 280
Cdd:pfam00055 145 KDDEVICTSEYSDISPLTGGEVIFSTLEGRPSANIfdYSPELQDWLTATNIRIRLLRLHTLGDEL--------LDDPSVL 216
|
250
....*....|....
gi 25145020 281 MRYFYSISDISIGG 294
Cdd:pfam00055 217 RKYYYAISDISVGG 230
|
|
| LamB |
smart00281 |
Laminin B domain; |
583-711 |
1.39e-49 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 172.83 E-value: 1.39e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 583 DRSLYYWKAPDSFKGNMLNSYGGYLHYDVYYVPTEQGATVFVADVAIEGNGIKIEYHSRIEFLPREKMTVAIPMSELSGW 662
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPDVILEGNGLRISHPAEGPPLPDELTTVEVRFREENWQ 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 663 YNAEarSPVDKADMMRALANVDRFTVRATYHQPQLQSSIFGLSLDTAVP 711
Cdd:smart00281 81 YYGG--RPVTREDLMMVLANLTAILIRATYSQQMAGSRLSDVSLEVAVP 127
|
|
| LamB |
smart00281 |
Laminin B domain; |
1341-1478 |
3.59e-41 |
|
Laminin B domain;
Pssm-ID: 214597 Cd Length: 127 Bit Score: 148.56 E-value: 3.59e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1341 DATPLYWPLPSTMLGDRTASYNGFLRFKIWNEDNRRGLHGIRPDqqyfrhfpqVIIFGNN-RIELEHIPMEINDDGIY-K 1418
Cdd:smart00281 1 DNEPVYWVAPEQFLGDKVTSYGGKLRYTLSFDGRRGGTHVSAPD---------VILEGNGlRISHPAEGPPLPDELTTvE 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1419 IRLHESEWRVRHspELTLTRKQMMVALQDTQGIYIRGTYTYpaRGDAINIQEVSLDVAVP 1478
Cdd:smart00281 72 VRFREENWQYYG--GRPVTREDLMMVLANLTAILIRATYSQ--QMAGSRLSDVSLEVAVP 127
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
588-713 |
2.23e-37 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 138.17 E-value: 2.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 588 YWKAPDSFKGNMLNSYGGYLHYDVYYVPTEQGAT-VFVADVAIEGNGIKIEYHSRIEFLPR--EKMTVAIPMSElSGWYN 664
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGGGSlNSEPDVILEGNGLRLSYSSPDQPPPDpgQEQTYSVRLHE-ENWRD 79
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 665 AEaRSPVDKADMMRALANVDRFTVRATYHQPQLQSSIFGLSLDTAVPAP 713
Cdd:pfam00052 80 SD-GAPVSREDFMMVLANLTAILIRATYSTGSGQVSLSNVSLDSAVPGG 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2471-2622 |
6.29e-30 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 117.52 E-value: 6.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2471 HLFRDGFANVSMSVSERTMSAITVIFNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVaELTSQNVYNDGK 2550
Cdd:cd00110 3 SFSGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQNGGDFLALELEDGRLVLRYDLGSGSL-VLSSKTPLNDGQ 81
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2551 EHTVKAIRTGSEMYLQVDSdaDRFNTVITGENTALNIENENHYVAGVPMtlNKEVFGDINWNGFIGCILTVK 2622
Cdd:cd00110 82 WHSVSVERNGRSVTLSVDG--ERVVESGSPGGSALLNLDGPLYLGGLPE--DLKSPGLPVSPGFVGCIRDLK 149
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2919-3065 |
1.76e-28 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 113.28 E-value: 1.76e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2919 SSHSRINFEAPYPNITDFTVKLSLQTETSNGMIWAWANyKNYTRYIFLDIIDGFATLEVKGHKQPKILKHlGNRINDGQW 2998
Cdd:cd00110 5 SGSSYVRLPTLPAPRTRLSISFSFRTTSPNGLLLYAGS-QNGGDFLALELEDGRLVLRYDLGSGSLVLSS-KTPLNDGQW 82
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2999 HDITVEKKNRSLKLIIDSLGPVEMTDCPTPK--VMKKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMN 3065
Cdd:cd00110 83 HSVSVERNGRSVTLSVDGERVVESGSPGGSAllNLDGPLYLGGLPEDLKSPGLPVSPGFVGCIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2937-3067 |
9.07e-28 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 110.51 E-value: 9.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2937 TVKLSLQTETSNGMIWAWANyKNYTRYIFLDIIDGFATLEVKGHKQPKILKHLGNRINDGQWHDITVEKKNRSLKLIIDS 3016
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGS-KGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSVDG 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 25145020 3017 LGPVEMTDCPTPKV--MKKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMNNR 3067
Cdd:smart00282 80 GNRVSGESPGGLTIlnLDGPLYLGGLPEDLKLPPLPVTPGFRGCIRNLKVNGK 132
|
|
| LamG |
smart00282 |
Laminin G domain; |
2492-2622 |
1.25e-27 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 110.12 E-value: 1.25e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2492 ITVIFNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVAELTSQNVYNDGKEHTVKAIRTGSEMYLQVDsDA 2571
Cdd:smart00282 2 ISFSFRTTSPNGLLLYAGSKGGGDYLALELRDGRLVLRYDLGSGPARLTSDPTPLNDGQWHRVAVERNGRSVTLSVD-GG 80
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 25145020 2572 DRFNTVITGENTALNIeNENHYVAGVPMTLNKevFGDINWNGFIGCILTVK 2622
Cdd:smart00282 81 NRVSGESPGGLTILNL-DGPLYLGGLPEDLKL--PPLPVTPGFRGCIRNLK 128
|
|
| Laminin_B |
pfam00052 |
Laminin B (Domain IV); |
1346-1480 |
2.08e-27 |
|
Laminin B (Domain IV);
Pssm-ID: 459652 Cd Length: 136 Bit Score: 109.67 E-value: 2.08e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1346 YWPLPSTMLGDRTASYNGFLRFKIWNEDNRRGlhGIRPDQqyfrhfPQVIIFGNNrIELEHIPMEI-----NDDGIYKIR 1420
Cdd:pfam00052 1 YWSAPEQFLGNKLTSYGGYLTYTVRYEPLPGG--GSLNSE------PDVILEGNG-LRLSYSSPDQpppdpGQEQTYSVR 71
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1421 LHESEWRvrHSPELTLTRKQMMVALQDTQGIYIRGTYTYPARGdaINIQEVSLDVAVPES 1480
Cdd:pfam00052 72 LHEENWR--DSDGAPVSREDFMMVLANLTAILIRATYSTGSGQ--VSLSNVSLDSAVPGG 127
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2655-2821 |
7.47e-25 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 102.88 E-value: 7.47e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2655 IGFPKPGYL-ITKGISIDNSSTFAFSFRTREENGTLVYQSSKlqkvskrdsedDGKGYIAFYLFRGYLVLHFgkdaSSRK 2733
Cdd:cd00110 2 VSFSGSSYVrLPTLPAPRTRLSISFSFRTTSPNGLLLYAGSQ-----------NGGDFLALELEDGRLVLRY----DLGS 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2734 EVVTFRSSHPYNDGQVHAVFMERNGKIISVKVDDKEIGDSQSLSDETSVgTTSGRLILGGFSDDLKPPNneIPITSFFIG 2813
Cdd:cd00110 67 GSLVLSSKTPLNDGQWHSVSVERNGRSVTLSVDGERVVESGSPGGSALL-NLDGPLYLGGLPEDLKSPG--LPVSPGFVG 143
|
....*...
gi 25145020 2814 CISDVFLN 2821
Cdd:cd00110 144 CIRDLKVN 151
|
|
| LamG |
smart00282 |
Laminin G domain; |
2675-2823 |
1.66e-24 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 101.26 E-value: 1.66e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2675 TFAFSFRTREENGTLVYQSSKlqkvskrdsedDGKGYIAFYLFRGYLVLHFgkDASSRKEVVTFrSSHPYNDGQVHAVFM 2754
Cdd:smart00282 1 SISFSFRTTSPNGLLLYAGSK-----------GGGDYLALELRDGRLVLRY--DLGSGPARLTS-DPTPLNDGQWHRVAV 66
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2755 ERNGKIISVKVDDKEIGDSQSLSDETSVGTTsGRLILGGFSDDLKPPNneIPITSFFIGCISDVFLNMK 2823
Cdd:smart00282 67 ERNGRSVTLSVDGGNRVSGESPGGLTILNLD-GPLYLGGLPEDLKLPP--LPVTPGFRGCIRNLKVNGK 132
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2680-2821 |
1.34e-20 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 89.79 E-value: 1.34e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2680 FRTREENGTLVYqssklqkvskrdSEDDGKGYIAFYLFRGYLVLHFgkDASSRkEVVTFRSSHPYNDGQVHAVFMERNGK 2759
Cdd:pfam02210 1 FRTRQPNGLLLY------------AGGGGSDFLALELVNGRLVLRY--DLGSG-PESLLSSGKNLNDGQWHSVRVERNGN 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2760 IISVKVDDKEIGdSQSLSDETSVGTTSGRLILGGFSDDLKPPNneIPITSFFIGCISDVFLN 2821
Cdd:pfam02210 66 TLTLSVDGQTVV-SSLPPGESLLLNLNGPLYLGGLPPLLLLPA--LPVRAGFVGCIRDVRVN 124
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2500-2618 |
8.40e-19 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 84.78 E-value: 8.40e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2500 SPNGLLYFRGSEaSGDFVAIYLNDGKVMFKINLGGGSVAELTSQNVYNDGKEHTVKAIRTGSEMYLQVDSdaDRFNTVIT 2579
Cdd:pfam02210 5 QPNGLLLYAGGG-GSDFLALELVNGRLVLRYDLGSGPESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDG--QTVVSSLP 81
|
90 100 110
....*....|....*....|....*....|....*....
gi 25145020 2580 GENTALNIENENHYVAGVPMTLNKEvfGDINWNGFIGCI 2618
Cdd:pfam02210 82 PGESLLLNLNGPLYLGGLPPLLLLP--ALPVRAGFVGCI 118
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2944-3067 |
2.06e-17 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 80.93 E-value: 2.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2944 TETSNGMIWAWANYKNytRYIFLDIIDGFATLEVKGHKQPKILKHLGNRINDGQWHDITVEKKNRSLKLIIDSLGPVEMT 3023
Cdd:pfam02210 3 TRQPNGLLLYAGGGGS--DFLALELVNGRLVLRYDLGSGPESLLSSGKNLNDGQWHSVRVERNGNTLTLSVDGQTVVSSL 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*.
gi 25145020 3024 DCPTPKVM--KKRVYVGGVISRHRRQFGLTTPGLDGCIRDFEMNNR 3067
Cdd:pfam02210 81 PPGESLLLnlNGPLYLGGLPPLLLLPALPVRAGFVGCIRDVRVNGE 126
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2496-2618 |
2.73e-15 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 75.05 E-value: 2.73e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2496 FNAFSPNGLLYFRGSEASGDFVAIYLNDGKVMFKINLGGGSVAELTSQNVyNDGKEHTVKAIRTGSEMYLQVDSDADRFN 2575
Cdd:pfam00054 1 FRTTEPSGLLLYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRSGDKL-NDGKWHSVELERNGRSGTLSVDGEARPTG 79
|
90 100 110 120
....*....|....*....|....*....|....*....|...
gi 25145020 2576 TVITGENTALNiENENHYVAGVPMTLNKEVFGDINwNGFIGCI 2618
Cdd:pfam00054 80 ESPLGATTDLD-VDGPLYVGGLPSLGVKKRRLAIS-PSFDGCI 120
|
|
| LamG |
smart00282 |
Laminin G domain; |
2285-2443 |
2.17e-14 |
|
Laminin G domain;
Pssm-ID: 214598 [Multi-domain] Cd Length: 132 Bit Score: 72.37 E-value: 2.17e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2285 TFHVSYRPLQqvSDAVILVSKTKGRrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHpinyVPSNDRvTWYHIDVLRI 2364
Cdd:smart00282 1 SISFSFRTTS--PNGLLLYAGSKGG----GDYLALELRDGRLVLRYDLGSGPARLTSDP----TPLNDG-QWHRVAVERN 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2365 GNAVNLTV----ALKESYDGGFKPRGAPVSVFVGnskddnsifntipgettidvGTDETVASDIGLTTHKFSGIVGGLRI 2440
Cdd:smart00282 70 GRSVTLSVdggnRVSGESPGGLTILNLDGPLYLG--------------------GLPEDLKLPPLPVTPGFRGCIRNLKV 129
|
...
gi 25145020 2441 DEV 2443
Cdd:smart00282 130 NGK 132
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2680-2821 |
2.90e-14 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 71.96 E-value: 2.90e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2680 FRTREENGTLVYqssklqkvskrDSEDDGKGYIAFYLFRGYLVLHFgkDASSRKEVVtfRSSHPYNDGQVHAVFMERNGK 2759
Cdd:pfam00054 1 FRTTEPSGLLLY-----------NGTQTERDFLALELRDGRLEVSY--DLGSGAAVV--RSGDKLNDGKWHSVELERNGR 65
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 25145020 2760 IISVKVDDKEIGDSQSLSDETSVGTTSGRLILGGFSDDLKPPnNEIPITSFFIGCISDVFLN 2821
Cdd:pfam00054 66 SGTLSVDGEARPTGESPLGATTDLDVDGPLYVGGLPSLGVKK-RRLAISPSFDGCIRDVIVN 126
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1086-1131 |
4.85e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 68.49 E-value: 4.85e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGC 1131
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1086-1134 |
8.11e-14 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 67.76 E-value: 8.11e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEGCTEC 1134
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
988-1033 |
8.47e-14 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 67.72 E-value: 8.47e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 988 CDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDAGC 1033
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYGDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1086-1130 |
1.96e-13 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 66.99 E-value: 1.96e-13
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 25145020 1086 CGCDPTGSEDVSCNLVTGQCVCKPGVTGLKCDSCLPNFYGLTSEG 1130
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQG 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
988-1036 |
1.53e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 64.30 E-value: 1.53e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 988 CDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDAGCQFC 1036
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
987-1034 |
2.46e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 63.53 E-value: 2.46e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 987 ACDCNDTGSIGSDCDQVSGQCNCKQGVFGKQCDQCRPSYFNFTDA--GCQ 1034
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQggGCQ 50
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1646-1694 |
6.28e-12 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 62.37 E-value: 6.28e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1646 PCDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERHAFINRVCTSC 1694
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQGGGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
423-480 |
7.31e-12 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 62.37 E-value: 7.31e-12
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*...
gi 25145020 423 CECDPVGSVSDACVRddqsaENGQkpgdCICKPGFGGRRCERCAPGYRNHPTCEPCPC 480
Cdd:pfam00053 1 CDCNPHGSLSDTCDP-----ETGQ----CLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1831-2226 |
1.50e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 70.48 E-value: 1.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELL-KMVTAQKL-----NETIfEDLKNRIDVLEQWMNDYRETIYDVS 1904
Cdd:PRK03918 333 LEEKEERLEELKKKLKELEKRLEELEERHELYEEAKaKKEELERLkkrltGLTP-EKLEKELEELEKAKEEIEEEISKIT 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1905 KK----DTADAERMSLV-----------VGKR----------INRYKEVSNEIEKLRVEAEDQiaysrnsIEKARSEelm 1959
Cdd:PRK03918 412 ARigelKKEIKELKKAIeelkkakgkcpVCGRelteehrkelLEEYTAELKRIEKELKEIEEK-------ERKLRKE--- 481
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1960 nmfedKEKINMTLAELPDLVEQCQnitlLYSQLID------EYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTEtenpL 2033
Cdd:PRK03918 482 -----LRELEKVLKKESELIKLKE----LAEQLKEleeklkKYNLEELEKKAEEYEKLKEKLIKLKGEIKSLKKE----L 548
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2034 KASHAYENIVEALKnatEAVDSAAEASEAVSKMLGSEGSESGDANEESLRSqLEKLKNE-SSLSNVDnSNAVKIVEELKK 2112
Cdd:PRK03918 549 EKLEELKKKLAELE---KKLDELEEELAELLKELEELGFESVEELEERLKE-LEPFYNEyLELKDAE-KELEREEKELKK 623
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2113 EKKDLTDRLGHLNELKTSI---VKRLGVIKNEASswDDKHDRM----------HSILKNGAKTAHERSANVKKESEGIKT 2179
Cdd:PRK03918 624 LEEELDKAFEELAETEKRLeelRKELEELEKKYS--EEEYEELreeylelsreLAGLRAELEELEKRREEIKKTLEKLKE 701
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|
gi 25145020 2180 EVSAI---KAEVEKLmNSTSSGVQEDMEKIRASRTGMEYGAqkLTKVNKL 2226
Cdd:PRK03918 702 ELEERekaKKELEKL-EKALERVEELREKVKKYKALLKERA--LSKVGEI 748
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1181-1229 |
2.14e-11 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 60.83 E-value: 2.14e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFFNFPTCEPCGC 1229
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
941-985 |
3.03e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 60.40 E-value: 3.03e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 941 CGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH-GDVENGC 985
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYyGDGPPGC 46
|
|
| Laminin_G_1 |
pfam00054 |
Laminin G domain; |
2944-3067 |
4.56e-11 |
|
Laminin G domain;
Pssm-ID: 395008 [Multi-domain] Cd Length: 131 Bit Score: 62.72 E-value: 4.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2944 TETSNGMIwAWANYKNYTRYIFLDIIDGFATLEVKGHKQPKILKHlGNRINDGQWHDITVEKKNRSLKLIIDSLGPVEMT 3023
Cdd:pfam00054 3 TTEPSGLL-LYNGTQTERDFLALELRDGRLEVSYDLGSGAAVVRS-GDKLNDGKWHSVELERNGRSGTLSVDGEARPTGE 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 25145020 3024 DCPTPKV---MKKRVYVGG--VISRHRRQFGLtTPGLDGCIRDFEMNNR 3067
Cdd:pfam00054 81 SPLGATTdldVDGPLYVGGlpSLGVKKRRLAI-SPSFDGCIRDVIVNGK 128
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
774-818 |
4.66e-11 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 60.06 E-value: 4.66e-11
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRGGE 818
Cdd:cd00055 2 CDCNGHgslSGQCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1647-1684 |
6.82e-11 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 59.63 E-value: 6.82e-11
10 20 30
....*....|....*....|....*....|....*...
gi 25145020 1647 CDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERH 1684
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGY 38
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1848-2260 |
8.53e-11 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 68.17 E-value: 8.53e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1848 VEKRLNRAQQEHKKAEELLKMVTAQK--LNETI--FEDLKNRIDVLEQWMNDYRETIYDVSKKDTADAERMSLVVGKRIN 1923
Cdd:PRK03918 312 IEKRLSRLEEEINGIEERIKELEEKEerLEELKkkLKELEKRLEELEERHELYEEAKAKKEELERLKKRLTGLTPEKLEK 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1924 RYKEVSNEIEKLRvEAEDQIAYSRNSIEKARSEELMNMFEDKE---KINMTLAELPDlvEQCQNITLLYSQLIDEYDEEy 2000
Cdd:PRK03918 392 ELEELEKAKEEIE-EEISKITARIGELKKEIKELKKAIEELKKakgKCPVCGRELTE--EHRKELLEEYTAELKRIEKE- 467
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2001 VQTAGRHAEKLEVQAQKiVDRFVDTRTETENPLKASHAYENIVEALK--NATEAVDSAAEASEAVSKMLGSEGSESgdan 2078
Cdd:PRK03918 468 LKEIEEKERKLRKELRE-LEKVLKKESELIKLKELAEQLKELEEKLKkyNLEELEKKAEEYEKLKEKLIKLKGEIK---- 542
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2079 eeSLRSQLEKLKN-ESSLSNVDNSnavkiVEELKKEKKDLTDRLGHL-----NELKTSIvKRLGVIKNEASSWDDKHDRM 2152
Cdd:PRK03918 543 --SLKKELEKLEElKKKLAELEKK-----LDELEEELAELLKELEELgfesvEELEERL-KELEPFYNEYLELKDAEKEL 614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2153 HSILKNGAKTAHERSAnVKKESEGIKTEVSAIKAEVEKLMNSTSsgvQEDMEKIRASRT--GMEYgAQKLTKVNKLstan 2230
Cdd:PRK03918 615 EREEKELKKLEEELDK-AFEELAETEKRLEELRKELEELEKKYS---EEEYEELREEYLelSREL-AGLRAELEEL---- 685
|
410 420 430
....*....|....*....|....*....|
gi 25145020 2231 QGRTDKMARNIAILKAKIEQAREKAYQIRL 2260
Cdd:PRK03918 686 EKRREEIKKTLEKLKEELEEREKAKKELEK 715
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1647-1684 |
1.54e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 58.52 E-value: 1.54e-10
10 20 30
....*....|....*....|....*....|....*...
gi 25145020 1647 CDCHPDGSLHGACNPLSGQCECKPGVTGRTCSMCQERH 1684
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGY 38
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
940-978 |
1.98e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 58.13 E-value: 1.98e-10
10 20 30
....*....|....*....|....*....|....*....
gi 25145020 940 PCGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH 978
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGY 39
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1036-1083 |
2.48e-10 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 57.71 E-value: 2.48e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1036 CHCNIYGSIeDGKCDQTTGKCECRENVEGTMCEKCADGYFNItSGDGC 1083
Cdd:smart00180 1 CDCDPGGSA-SGTCDPDTGQCECKPNVTGRRCDRCAPGYYGD-GPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
774-818 |
2.97e-10 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 57.75 E-value: 2.97e-10
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRGGE 818
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1036-1084 |
3.97e-10 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 57.36 E-value: 3.97e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 1036 CHCNIYGSiEDGKCDQTTGKCECRENVEGTMCEKCADGYFNITS-GDGCE 1084
Cdd:cd00055 2 CDCNGHGS-LSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSqGGGCQ 50
|
|
| PRK01156 |
PRK01156 |
chromosome segregation protein; Provisional |
1846-2246 |
3.97e-10 |
|
chromosome segregation protein; Provisional
Pssm-ID: 100796 [Multi-domain] Cd Length: 895 Bit Score: 66.08 E-value: 3.97e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1846 EYVEKRLNRAQQEHKKAEELLKMVTAQKLNETIFEDLKNRIDVLEQWMNDYRETIYDVSKKD------TADAERMSLVVG 1919
Cdd:PRK01156 315 SNIDAEINKYHAIIKKLSVLQKDYNDYIKKKSRYDDLNNQILELEGYEMDYNSYLKSIESLKkkieeySKNIERMSAFIS 394
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1920 KRINRY-------KEVSNEIEKLRVEAEDQIAYSRNSIEKARS-----EELMNMFEDKEKINMTLAELPDlvEQCQNITL 1987
Cdd:PRK01156 395 EILKIQeidpdaiKKELNEINVKLQDISSKVSSLNQRIRALREnldelSRNMEMLNGQSVCPVCGTTLGE--EKSNHIIN 472
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1988 LYSQLIDEYDEEYvqtagrhaEKLEVQAQKIVDRFVDTRTETE----NPLKASHAYENIVEALK-NATEAVDSAAEASEA 2062
Cdd:PRK01156 473 HYNEKKSRLEEKI--------REIEIEVKDIDEKIVDLKKRKEylesEEINKSINEYNKIESARaDLEDIKIKINELKDK 544
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2063 VSKMLGSEgSESGDANEESLRSQLEK-LKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGHLN----ELKTSIVKRLGV 2137
Cdd:PRK01156 545 HDKYEEIK-NRYKSLKLEDLDSKRTSwLNALAVISLIDIETNRSRSNEIKKQLNDLESRLQEIEigfpDDKSYIDKSIRE 623
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2138 IKNEASSWDDKHDRMHSiLKNGAKTAHERSANVKKESEGIKT------EVSAIKAEVEKLMNSTSSGVQedmeKIRASRT 2211
Cdd:PRK01156 624 IENEANNLNNKYNEIQE-NKILIEKLRGKIDNYKKQIAEIDSiipdlkEITSRINDIEDNLKKSRKALD----DAKANRA 698
|
410 420 430
....*....|....*....|....*....|....*.
gi 25145020 2212 GMEYGAQKL-TKVNKLSTANQGRTDKMARNIAILKA 2246
Cdd:PRK01156 699 RLESTIEILrTRINELSDRINDINETLESMKKIKKA 734
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1838-2259 |
8.89e-10 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 64.68 E-value: 8.89e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1838 LNATVERGEYVE--KRLNRAQQEHKKAEELLKMVTAQK---------LNETI--FEDLKNRIDVLEQWMNDYRETIydvs 1904
Cdd:PRK02224 192 LKAQIEEKEEKDlhERLNGLESELAELDEEIERYEEQReqaretrdeADEVLeeHEERREELETLEAEIEDLRETI---- 267
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1905 kkdtADAERMSLVVGKRINRYKEVSNEIEKLRVEAEDQIAYSRNSIE--KARSEELmnmfEDKEkinmtlAELPDLVEQC 1982
Cdd:PRK02224 268 ----AETEREREELAEEVRDLRERLEELEEERDDLLAEAGLDDADAEavEARREEL----EDRD------EELRDRLEEC 333
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1983 -QNITLLYSQlIDEYDEEYVQTAGRHAEKLEvQAQKIVDRFVDTRTETEnplKASHAYENIVEALKNATEAVDSAAEASE 2061
Cdd:PRK02224 334 rVAAQAHNEE-AESLREDADDLEERAEELRE-EAAELESELEEAREAVE---DRREEIEELEEEIEELRERFGDAPVDLG 408
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2062 AVSKMLGSEGSESGDANEE--SLRSQLEKL-----KNESSLS---------NVDNSNAVKIVEELKKEKKDLTDRLGHLN 2125
Cdd:PRK02224 409 NAEDFLEELREERDELREReaELEATLRTArerveEAEALLEagkcpecgqPVEGSPHVETIEEDRERVEELEAELEDLE 488
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2126 ELKTSIVKRLgvikNEASSWDDKHDRMHSiLKNGAKTAHERSANVKKESEGIKTEVSAIKAEVEKLmnstSSGVQEDMEK 2205
Cdd:PRK02224 489 EEVEEVEERL----ERAEDLVEAEDRIER-LEERREDLEELIAERRETIEEKRERAEELRERAAEL----EAEAEEKREA 559
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....
gi 25145020 2206 IRASRTGMEYGAQKLTKVNKLSTANQGRTDKMARnIAILKAKIEQAREKAYQIR 2259
Cdd:PRK02224 560 AAEAEEEAEEAREEVAELNSKLAELKERIESLER-IRTLLAAIADAEDEIERLR 612
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
423-474 |
1.02e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 56.21 E-value: 1.02e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 423 CECDPVGSVSDACVRDDqsaengqkpGDCICKPGFGGRRCERCAPGYRNHPT 474
Cdd:cd00055 2 CDCNGHGSLSGQCDPGT---------GQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1036-1083 |
1.65e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 55.82 E-value: 1.65e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 1036 CHCNIYGSIEDGkCDQTTGKCECRENVEGTMCEKCADGYFN--ITSGDGC 1083
Cdd:pfam00053 1 CDCNPHGSLSDT-CDPETGQCLCKPGVTGRHCDRCKPGYYGlpSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
423-475 |
2.37e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 55.01 E-value: 2.37e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 423 CECDPVGSVSDACVRDDqsaengqkpGDCICKPGFGGRRCERCAPGY--RNHPTC 475
Cdd:smart00180 1 CDCDPGGSASGTCDPDT---------GQCECKPNVTGRRCDRCAPGYygDGPPGC 46
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1181-1223 |
2.50e-09 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 55.05 E-value: 2.50e-09
10 20 30 40
....*....|....*....|....*....|....*....|...
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFFNFPT 1223
Cdd:cd00055 2 CDCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPS 44
|
|
| LamG |
cd00110 |
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have ... |
2273-2441 |
3.35e-09 |
|
Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of purposes including signal transduction via cell-surface steroid receptors, adhesion, migration and differentiation through mediation of cell adhesion molecules.
Pssm-ID: 238058 [Multi-domain] Cd Length: 151 Bit Score: 58.20 E-value: 3.35e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2273 SYISPASPSPVNTFHVSYRPLQqvSDAVILVSKTKGRrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHPInyvpsND 2352
Cdd:cd00110 11 RLPTLPAPRTRLSISFSFRTTS--PNGLLLYAGSQNG----GDFLALELEDGRLVLRYDLGSGSLVLSSKTPL-----ND 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2353 RvTWYHIDVLRIGNAVNLTV----ALKESYDGGFKPRGAPVSVFVGnskddnsifntipgettidvGTDETVASDIGLTT 2428
Cdd:cd00110 80 G-QWHSVSVERNGRSVTLSVdgerVVESGSPGGSALLNLDGPLYLG--------------------GLPEDLKSPGLPVS 138
|
170
....*....|...
gi 25145020 2429 HKFSGIVGGLRID 2441
Cdd:cd00110 139 PGFVGCIRDLKVN 151
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1849-2250 |
3.85e-09 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 62.73 E-value: 3.85e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1849 EKRLNRAQQEHKKAEELLKMVTAQ-------------KLNETI--FEDLKNRIDVLEQWMNDYRETIYDVSKKDTADAER 1913
Cdd:TIGR04523 123 EVELNKLEKQKKENKKNIDKFLTEikkkekeleklnnKYNDLKkqKEELENELNLLEKEKLNIQKNIDKIKNKLLKLELL 202
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1914 MSLVVgKRINRYKEVSNEIEKLrveaEDQiaysRNSIEKARSEELMNMFEDKEKINMTLAELPDLVEQCQNITllySQLI 1993
Cdd:TIGR04523 203 LSNLK-KKIQKNKSLESQISEL----KKQ----NNQLKDNIEKKQQEINEKTTEISNTQTQLNQLKDEQNKIK---KQLS 270
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1994 DEYDEeyVQTAGRHAEKLEVQAQKIvdrfvdtRTETENpLKaSHAYENIVEALKNATEAVDSAAEASEavskmlgSEGSE 2073
Cdd:TIGR04523 271 EKQKE--LEQNNKKIKELEKQLNQL-------KSEISD-LN-NQKEQDWNKELKSELKNQEKKLEEIQ-------NQISQ 332
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2074 sgdaNEE---SLRSQLEKLKNESSLSNVDNSNAVKIVEE----LKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEASSWD 2146
Cdd:TIGR04523 333 ----NNKiisQLNEQISQLKKELTNSESENSEKQRELEEkqneIEKLKKENQSYKQEIKNLESQINDLESKIQNQEKLNQ 408
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2147 DKHDRMHSILKNGAKTAHE----RSANVKKESE--GIKTEVSAIKAEVEKLMNSTSSgVQEDMEKIRAS----RTGMEYG 2216
Cdd:TIGR04523 409 QKDEQIKKLQQEKELLEKEierlKETIIKNNSEikDLTNQDSVKELIIKNLDNTRES-LETQLKVLSRSinkiKQNLEQK 487
|
410 420 430 440
....*....|....*....|....*....|....*....|.
gi 25145020 2217 AQKLT-KVNKLSTANQ------GRTDKMARNIAILKAKIEQ 2250
Cdd:TIGR04523 488 QKELKsKEKELKKLNEekkeleEKVKDLTKKISSLKEKIEK 528
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1181-1224 |
3.87e-09 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 54.62 E-value: 3.87e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1181 CDCSDIGSDGGMCNTFTGQCKCKAAYVGLKCDLCTHGFF--NFPTC 1224
Cdd:smart00180 1 CDCDPGGSASGTCDPDTGQCECKPNVTGRRCDRCAPGYYgdGPPGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
941-990 |
4.09e-09 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 54.67 E-value: 4.09e-09
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 25145020 941 CGCHTQGAVNPQCSEENGECECKENYIGAQCDRCKENH-GDveNGCPACDC 990
Cdd:pfam00053 1 CDCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYyGL--PSDPPQGC 49
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1843-2255 |
2.18e-08 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 60.54 E-value: 2.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1843 ERGEYVEKRLNRAQQEHKKAEELLKMVT-AQKLNETIFEDLKNRIDVLEQwmndyRETIYDVSKKDTADAERMSLVVGKR 1921
Cdd:PTZ00121 1312 EEAKKADEAKKKAEEAKKKADAAKKKAEeAKKAAEAAKAEAEAAADEAEA-----AEEKAEAAEKKKEEAKKKADAAKKK 1386
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1922 ---INRYKEVSNEIEKLRVEAEDqiaYSRNSIEKARSEELMNMFEDKEKINmtlaELPDLVEQCQNITLLYSQLIDEYDE 1998
Cdd:PTZ00121 1387 aeeKKKADEAKKKAEEDKKKADE---LKKAAAAKKKADEAKKKAEEKKKAD----EAKKKAEEAKKADEAKKKAEEAKKA 1459
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1999 EYVQTAGRHAEKLEvQAQKIVDrfvDTRTETENPLKASHAYENiVEALKNATEAVDSAAEASEAVSKMLGSEGSESGDAN 2078
Cdd:PTZ00121 1460 EEAKKKAEEAKKAD-EAKKKAE---EAKKADEAKKKAEEAKKK-ADEAKKAAEAKKKADEAKKAEEAKKADEAKKAEEAK 1534
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2079 E-ESLRSQLEKLKNES--SLSNVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGV------------------ 2137
Cdd:PTZ00121 1535 KaDEAKKAEEKKKADElkKAEELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEvmklyeeekkmkaeeakk 1614
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2138 -----IKNEASSWDDKHDRMHSILKNGAKTAHERSANVKKESE--GIKTEVSAIKAEVEKLMNSTSSGVQEDMEKIRASR 2210
Cdd:PTZ00121 1615 aeeakIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEenKIKAAEEAKKAEEDKKKAEEAKKAEEDEKKAAEAL 1694
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 25145020 2211 TGMEYGAQKLTKVNKLSTANQGRTDKMARNIAILKAKIEQAREKA 2255
Cdd:PTZ00121 1695 KKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEA 1739
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
296-343 |
2.19e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 52.36 E-value: 2.19e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 25145020 296 CICYGHAESCPS-DPVTGQfkCECRHNTCGESCNRCCPLFNQLPWKPGT 343
Cdd:cd00055 2 CDCNGHGSLSGQcDPGTGQ--CECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
774-816 |
2.44e-08 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 52.31 E-value: 2.44e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 774 CDCHGN---SEECDPFTGECLnCRHNTTGSRCELCKPGHVGNPSRG 816
Cdd:smart00180 1 CDCDPGgsaSGTCDPDTGQCE-CKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1880-2161 |
2.80e-08 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 58.00 E-value: 2.80e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1880 EDLKNRIDVLEQWMNDYRETIYDVSK--KDTAdAERMSLvvgkrINRYKEVSNEIEKLRvEAEDQIaysrnsIEKARseE 1957
Cdd:COG1340 11 EELEEKIEELREEIEELKEKRDELNEelKELA-EKRDEL-----NAQVKELREEAQELR-EKRDEL------NEKVK--E 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1958 LmnmfedKEKINMTLAELPDLVEQcqnitllysqlIDEYDEEYVQTAGRHA---------EKLEVQAQ----------KI 2018
Cdd:COG1340 76 L------KEERDELNEKLNELREE-----------LDELRKELAELNKAGGsidklrkeiERLEWRQQtevlspeeekEL 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2019 VDRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASEAVSKMlgseGSESGDANEE--SLRSQLEKLKNESSLS 2096
Cdd:COG1340 139 VEKIKELEKELEKAKKALEKNEKLKELRAELKELRKEAEEIHKKIKEL----AEEAQELHEEmiELYKEADELRKEADEL 214
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 2097 NVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIK--NEASSWDDKHDRMHSILKNGAK 2161
Cdd:COG1340 215 HKEIVEAQEKADELHEEIIELQKELRELRKELKKLRKKQRALKreKEKEELEEKAEEIFEKLKKGEK 281
|
|
| SCP-1 |
pfam05483 |
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major ... |
1843-2205 |
6.68e-08 |
|
Synaptonemal complex protein 1 (SCP-1); Synaptonemal complex protein 1 (SCP-1) is the major component of the transverse filaments of the synaptonemal complex. Synaptonemal complexes are structures that are formed between homologous chromosomes during meiotic prophase.
Pssm-ID: 114219 [Multi-domain] Cd Length: 787 Bit Score: 58.58 E-value: 6.68e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1843 ERGEYVEKRLNRAQQEHKKAEELLKMVTAqklneTIFEDLKNRIDVLEQWMNDYRETIYDVSKKdTADAERMSlvvgkRI 1922
Cdd:pfam05483 331 EEKEAQMEELNKAKAAHSFVVTEFEATTC-----SLEELLRTEQQRLEKNEDQLKIITMELQKK-SSELEEMT-----KF 399
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1923 NRYKEVsnEIEKLR-VEAEDQ-IAYSRNSIEK------ARSEELMNMFEDKEKinmtlaELPDLVEQCQNITL---LYSQ 1991
Cdd:pfam05483 400 KNNKEV--ELEELKkILAEDEkLLDEKKQFEKiaeelkGKEQELIFLLQAREK------EIHDLEIQLTAIKTseeHYLK 471
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1992 LIDEYDEEYVQTAGR------HAEKLEVQAQKIV----DRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASE 2061
Cdd:pfam05483 472 EVEDLKTELEKEKLKnieltaHCDKLLLENKELTqeasDMTLELKKHQEDIINCKKQEERMLKQIENLEEKEMNLRDELE 551
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2062 AVSKMLGSEGSESG---DANEESLRS-QLEKLKNESSLSNVDNS---------NAVKIVEELKKEKKDLTDRlghlnelK 2128
Cdd:pfam05483 552 SVREEFIQKGDEVKcklDKSEENARSiEYEVLKKEKQMKILENKcnnlkkqieNKNKNIEELHQENKALKKK-------G 624
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 25145020 2129 TSIVKRLGVikneassWDDKHDRMHSILKNGAKTAHERSANVKKESEGIKTEVSAIKAEVEKLMNSTSSGV--QEDMEK 2205
Cdd:pfam05483 625 SAENKQLNA-------YEIKVNKLELELASAKQKFEEIIDNYQKEIEDKKISEEKLLEEVEKAKAIADEAVklQKEIDK 696
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1539-1583 |
7.83e-08 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 50.82 E-value: 7.83e-08
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1539 PCSCHGH---SQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREGG 1583
Cdd:cd00055 1 PCDCNGHgslSGQCDPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGG 47
|
|
| EzrA |
pfam06160 |
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like ... |
1884-2267 |
1.05e-07 |
|
Septation ring formation regulator, EzrA; During the bacterial cell cycle, the tubulin-like cell-division protein FtsZ polymerizes into a ring structure that establishes the location of the nascent division site. EzrA modulates the frequency and position of FtsZ ring formation. The structure contains 5 spectrin like alpha helical repeats.
Pssm-ID: 428797 [Multi-domain] Cd Length: 542 Bit Score: 57.56 E-value: 1.05e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1884 NRIDVLEQWMNDYRE--TIYDVSKkdtadAERMSLV------VGKRINRYKEVSN----EIEKLRVEAEDQIAYSRnsIE 1951
Cdd:pfam06160 10 KEIDELEERKNELMNlpVQEELSK-----VKKLNLTgetqekFEEWRKKWDDIVTkslpDIEELLFEAEELNDKYR--FK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1952 KARS-----EELMNMFEdkEKINMTLAELPDLVEQCQNITLLYSQLIDEYDEeyVQT---AGRHA-----EKLEVQAQKI 2018
Cdd:pfam06160 83 KAKKaldeiEELLDDIE--EDIKQILEELDELLESEEKNREEVEELKDKYRE--LRKtllANRFSygpaiDELEKQLAEI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2019 VDRFV--DTRTETENPLKAShayeNIVEALKNATEAVDSA-------------------AEASEAVSKMLGsEGSESGDA 2077
Cdd:pfam06160 159 EEEFSqfEELTESGDYLEAR----EVLEKLEEETDALEELmedipplyeelktelpdqlEELKEGYREMEE-EGYALEHL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2078 NEESLRSQLEKL--KNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKneasswdDKHDRMHSI 2155
Cdd:pfam06160 234 NVDKEIQQLEEQleENLALLENLELDEAEEALEEIEERIDQLYDLLEKEVDAKKYVEKNLPEIE-------DYLEHAEEQ 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2156 LKN-GAKTAH------------ERSANVKKESEGIKTEVSAIKAEVEKlMNSTSSGVQEDMEKIRasrtgmeygaQKLTK 2222
Cdd:pfam06160 307 NKElKEELERvqqsytlnenelERVRGLEKQLEELEKRYDEIVERLEE-KEVAYSELQEELEEIL----------EQLEE 375
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 25145020 2223 VNKlstanqgRTDKMARNIAILKAKIEQAREKAYQIRLSLNSGER 2267
Cdd:pfam06160 376 IEE-------EQEEFKESLQSLRKDELEAREKLDEFKLELREIKR 413
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1831-2211 |
1.56e-07 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 57.34 E-value: 1.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLKMVTAQkLNE--TIFEDLKNRIDvlEQWMNDYRETIYDVSKKDT 1908
Cdd:TIGR04523 248 ISNTQTQLNQLKDEQNKIKKQLSEKQKELEQNNKKIKELEKQ-LNQlkSEISDLNNQKE--QDWNKELKSELKNQEKKLE 324
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1909 aDAERMSLVVGKRINRYKEVSNEIEKLR-------VEAEDQIAYSRNSIEKARSE----------------ELMNMFEDK 1965
Cdd:TIGR04523 325 -EIQNQISQNNKIISQLNEQISQLKKELtnsesenSEKQRELEEKQNEIEKLKKEnqsykqeiknlesqinDLESKIQNQ 403
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1966 EKINMTLAELPDLVEQCQN-----ITLLYSQLIDEYDEEyvqtagRHAEKLEVQAQKIVDRFVDTRTETENPLKA-SHAY 2039
Cdd:TIGR04523 404 EKLNQQKDEQIKKLQQEKEllekeIERLKETIIKNNSEI------KDLTNQDSVKELIIKNLDNTRESLETQLKVlSRSI 477
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2040 ENIVEALKNATEAVDS-----------AAEASEAVsKMLGSEGSESgDANEESLRS------------------------ 2084
Cdd:TIGR04523 478 NKIKQNLEQKQKELKSkekelkklneeKKELEEKV-KDLTKKISSL-KEKIEKLESekkekeskisdledelnkddfelk 555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2085 -------------QLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLghlnELKTSIVKRLgviKNEASSWDDKHDR 2151
Cdd:TIGR04523 556 kenlekeideknkEIEELKQTQKSLKKKQEEKQELIDQKEKEKKDLIKEI----EEKEKKISSL---EKELEKAKKENEK 628
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2152 MHSILKngaktahersaNVKKESEGIKTEVSAIKAEVEKLMNSTSsgvqEDMEKIRASRT 2211
Cdd:TIGR04523 629 LSSIIK-----------NIKSKKNKLKQEVKQIKETIKEIRNKWP----EIIKKIKESKT 673
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1835-2253 |
1.99e-07 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 57.46 E-value: 1.99e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1835 EAHLNATVERGEYVEKRLNRAQQEHKKAEELLKMVTAQKLNEtifedlKNRIDVLEQWMNDYRETiyDVSKKDTADAERM 1914
Cdd:PTZ00121 1259 EARMAHFARRQAAIKAEEARKADELKKAEEKKKADEAKKAEE------KKKADEAKKKAEEAKKA--DEAKKKAEEAKKK 1330
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1915 SLVVGKRINRYKEvSNEIEKLRVEA----------EDQIAYSRNSIEKARSEELMNMFEDKEKINmtlaELPDLVEQCQn 1984
Cdd:PTZ00121 1331 ADAAKKKAEEAKK-AAEAAKAEAEAaadeaeaaeeKAEAAEKKKEEAKKKADAAKKKAEEKKKAD----EAKKKAEEDK- 1404
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1985 itllysQLIDEYDEEyvQTAGRHAEKLEVQAQKiVDRFVDTRTETENPLKASHAYENIVEALK--NATEAVDSAAEASEA 2062
Cdd:PTZ00121 1405 ------KKADELKKA--AAAKKKADEAKKKAEE-KKKADEAKKKAEEAKKADEAKKKAEEAKKaeEAKKKAEEAKKADEA 1475
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2063 VSKM--------LGSEGSESGDANEESLRSQLEKLKNESSLSNVDNSNA--------VKIVEELKK-EKKDLTDRLGHLN 2125
Cdd:PTZ00121 1476 KKKAeeakkadeAKKKAEEAKKKADEAKKAAEAKKKADEAKKAEEAKKAdeakkaeeAKKADEAKKaEEKKKADELKKAE 1555
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2126 ELKTSIVKRLGVIKNEASSWDDKHDRMHSILKNGAKTAHERSANVKKESEGIKTEvSAIKAEVEKLMNSTSSGVQEDMEK 2205
Cdd:PTZ00121 1556 ELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAE-EAKKAEEAKIKAEELKKAEEEKKK 1634
|
410 420 430 440
....*....|....*....|....*....|....*....|....*...
gi 25145020 2206 IRASRTGMEYGAQKLTKVNKLSTANQGRTDKMARNIAILKAKIEQARE 2253
Cdd:PTZ00121 1635 VEQLKKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEEDKKKAEEAKK 1682
|
|
| YhaN |
COG4717 |
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown]; |
1833-2261 |
2.04e-07 |
|
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
Pssm-ID: 443752 [Multi-domain] Cd Length: 641 Bit Score: 56.70 E-value: 2.04e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLKMVTA----QKLNETI------FEDLKNRIDVLEQWMNDYRE---T 1899
Cdd:COG4717 92 ELQEELEELEEELEELEAELEELREELEKLEKLLQLLPLyqelEALEAELaelperLEELEERLEELRELEEELEEleaE 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1900 IYDVSKKDTADAERMSLVVGKRINRYKEVSNEIEKLRVEAEDQIAYSRNSIEKARS-----EELMNMFEDKEKIN----- 1969
Cdd:COG4717 172 LAELQEELEELLEQLSLATEEELQDLAEELEELQQRLAELEEELEEAQEELEELEEeleqlENELEAAALEERLKearll 251
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1970 -----------MTLAELPDLVEQCQNITLLYSQLI-DEYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTE---TENPLK 2034
Cdd:COG4717 252 lliaaallallGLGGSLLSLILTIAGVLFLVLGLLaLLFLLLAREKASLGKEAEELQALPALEELEEEELEellAALGLP 331
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2035 ASHAYENIVEALKNATEAVDSAAEASEavskmlgsegsesgdANEESLRSQLEKLKNES-SLSNVDNSNAVKIVEELKKE 2113
Cdd:COG4717 332 PDLSPEELLELLDRIEELQELLREAEE---------------LEEELQLEELEQEIAALlAEAGVEDEEELRAALEQAEE 396
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2114 KKDLTDRLGHLNElktsivkRLGVIKNEASSWDDKHDRmhSILKNGAKTAHERSANVKKESEGIKTEVSAIKAEVEKLMN 2193
Cdd:COG4717 397 YQELKEELEELEE-------QLEELLGELEELLEALDE--EELEEELEELEEELEELEEELEELREELAELEAELEQLEE 467
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25145020 2194 StssgvqEDMEKIRASRtgmeygAQKLTKVNKLstANQGRTDKMARNIailkakIEQAREKAYQIRLS 2261
Cdd:COG4717 468 D------GELAELLQEL------EELKAELREL--AEEWAALKLALEL------LEEAREEYREERLP 515
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
889-943 |
2.84e-07 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 49.27 E-value: 2.84e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 889 CTCNGNIDPmgIGNCDSETGKCLkCIGHTTGDSCESCKEHHWGNaqlHTCKPCGC 943
Cdd:pfam00053 1 CDCNPHGSL--SDTCDPETGQCL-CKPGVTGRHCDRCKPGYYGL---PSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
477-526 |
5.51e-07 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 48.50 E-value: 5.51e-07
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 477 PCPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHLsASNPLGCQ 526
Cdd:cd00055 1 PCDCNGHGSLS-GQCDPGTgqCECKPNTTGRRCDRCAPGYYGL-PSQGGGCQ 50
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1833-2127 |
9.06e-07 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 55.05 E-value: 9.06e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVERGEYVEKRLNRaqqehkkAEELLKMvtaqklnETIFEDLKNRIDVLEQWMNDYRETIydvskkdTADAE 1912
Cdd:PRK02224 479 ELEAELEDLEEEVEEVEERLER-------AEDLVEA-------EDRIERLEERREDLEELIAERRETI-------EEKRE 537
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1913 RMSlvvgkrinrykEVSNEIEKLRVEAEDQiaysRNSIEKARsEELMNMFEDKEKINMTLAELPDLVEQCQNITLLYSqL 1992
Cdd:PRK02224 538 RAE-----------ELRERAAELEAEAEEK----REAAAEAE-EEAEEAREEVAELNSKLAELKERIESLERIRTLLA-A 600
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1993 IDEYDEEyvqtAGRHAEKLEVQAQKIVDR--FVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASEAVSKMlgse 2070
Cdd:PRK02224 601 IADAEDE----IERLREKREALAELNDERreRLAEKRERKRELEAEFDEARIEEAREDKERAEEYLEQVEEKLDEL---- 672
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 2071 gsesgDANEESLRSQLEKLKNEsslsnvdnsnaVKIVEELKKEKKDLTDRLGHLNEL 2127
Cdd:PRK02224 673 -----REERDDLQAEIGAVENE-----------LEELEELRERREALENRVEALEAL 713
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1227-1281 |
1.42e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 47.35 E-value: 1.42e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1227 CGCNAAGTDPLQCKDGQclcneiGECPCKKNVHGTKCDQCGEGTFSLDSSNLKGC 1281
Cdd:pfam00053 1 CDCNPHGSLSDTCDPET------GQCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
478-525 |
1.55e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 47.35 E-value: 1.55e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 478 CPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHLSASNPLGC 525
Cdd:pfam00053 1 CDCNPHGSLS-DTCDPETgqCLCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
889-939 |
1.97e-06 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 46.96 E-value: 1.97e-06
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 25145020 889 CTCNGNIDPMGigNCDSETGKCLkCIGHTTGDSCESCKEHHWGNA-QLHTCK 939
Cdd:cd00055 2 CDCNGHGSLSG--QCDPGTGQCE-CKPNTTGRRCDRCAPGYYGLPsQGGGCQ 50
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1540-1582 |
2.37e-06 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 46.54 E-value: 2.37e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1540 CSCHG---HSQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREG 1582
Cdd:smart00180 1 CDCDPggsASGTCDPDTGQC-ECKPNVTGRRCDRCAPGYYGDGPPG 45
|
|
| SMC_prok_B |
TIGR02168 |
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ... |
1836-2259 |
3.53e-06 |
|
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274008 [Multi-domain] Cd Length: 1179 Bit Score: 53.14 E-value: 3.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1836 AHLNATVERGEYVEKRLNRAQQEHKKAEELLKMVTAQ---------KLNETI------FEDLKNRIDVLEQWMNDYRETI 1900
Cdd:TIGR02168 232 LRLEELREELEELQEELKEAEEELEELTAELQELEEKleelrlevsELEEEIeelqkeLYALANEISRLEQQKQILRERL 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1901 YDVSKK------DTADAERMSLVVGKRINRYKEVSNEIEK--------------LRVEAEDQIAYSRNSIEKARSeELMN 1960
Cdd:TIGR02168 312 ANLERQleeleaQLEELESKLDELAEELAELEEKLEELKEelesleaeleeleaELEELESRLEELEEQLETLRS-KVAQ 390
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1961 MFEDKEKINMTLAELPDLVEQcqnitllysqlIDEYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTETENplKASHAYE 2040
Cdd:TIGR02168 391 LELQIASLNNEIERLEARLER-----------LEDRRERLQQEIEELLKKLEEAELKELQAELEELEEELE--ELQEELE 457
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2041 NIVEALKNATEAVDSAAEASEAVSKMLGSEGSESgdaneESLRSQLEKLKNEsslsnvdnSNAVKIVEELKKEKKDLTDR 2120
Cdd:TIGR02168 458 RLEEALEELREELEEAEQALDAAERELAQLQARL-----DSLERLQENLEGF--------SEGVKALLKNQSGLSGILGV 524
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2121 LGHL----NELKTSIVKRLG------VIKNEASSWDD-KHDRMHSILK--------NGAKTAHERSANVKKESEGIKT-- 2179
Cdd:TIGR02168 525 LSELisvdEGYEAAIEAALGgrlqavVVENLNAAKKAiAFLKQNELGRvtflpldsIKGTEIQGNDREILKNIEGFLGva 604
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2180 -EVSAIKAEVEKLMNSTSSGV---------QEDMEKIRA------------SRTGMEYGAQKLTKVNKLSTAN-----QG 2232
Cdd:TIGR02168 605 kDLVKFDPKLRKALSYLLGGVlvvddldnaLELAKKLRPgyrivtldgdlvRPGGVITGGSAKTNSSILERRReieelEE 684
|
490 500
....*....|....*....|....*..
gi 25145020 2233 RTDKMARNIAILKAKIEQAREKAYQIR 2259
Cdd:TIGR02168 685 KIEELEEKIAELEKALAELRKELEELE 711
|
|
| PRK03918 |
PRK03918 |
DNA double-strand break repair ATPase Rad50; |
1910-2229 |
3.85e-06 |
|
DNA double-strand break repair ATPase Rad50;
Pssm-ID: 235175 [Multi-domain] Cd Length: 880 Bit Score: 52.76 E-value: 3.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1910 DAERMSLVVGK--RINRY-------KEVSNEIEKLRVEAEDQIAYSRNsIEKARSEELMNMFEDKEKINMTLAELPDLVE 1980
Cdd:PRK03918 143 SDESREKVVRQilGLDDYenayknlGEVIKEIKRRIERLEKFIKRTEN-IEELIKEKEKELEEVLREINEISSELPELRE 221
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1981 QCQNITLLYSQLiDEYDEEyVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLKASHAYENIVEALKNATEAvdsaAEAS 2060
Cdd:PRK03918 222 ELEKLEKEVKEL-EELKEE-IEELEKELESLEGSKRKLEEKIRELEERIEELKKEIEELEEKVKELKELKEK----AEEY 295
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2061 EAVSKmlgsegsesgdaneesLRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKN 2140
Cdd:PRK03918 296 IKLSE----------------FYEEYLDELREIEKRLSRLEEEINGIEERIKELEEKEERLEELKKKLKELEKRLEELEE 359
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2141 EASSWDDkhdrmhsilkngAKTAHERSANVKKESEGIktEVSAIKAEVEKLMNSTSSgVQEDMEKIRASRTGME-YGAQK 2219
Cdd:PRK03918 360 RHELYEE------------AKAKKEELERLKKRLTGL--TPEKLEKELEELEKAKEE-IEEEISKITARIGELKkEIKEL 424
|
330
....*....|
gi 25145020 2220 LTKVNKLSTA 2229
Cdd:PRK03918 425 KKAIEELKKA 434
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1827-2131 |
5.85e-06 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 52.38 E-value: 5.85e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1827 LDGMLMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLKMV------TAQKL--NETIFEDLKNRIDVLEQWMNDYRE 1898
Cdd:TIGR02169 700 IENRLDELSQELSDASRKIGEIEKEIEQLEQEEEKLKERLEELeedlssLEQEIenVKSELKELEARIEELEEDLHKLEE 779
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1899 TIYD-------------VSKKDTADAERMSLV-----VGKRINR-------YKEVSNEIEKLRVEAEDQIAYSRNSIE-- 1951
Cdd:TIGR02169 780 ALNDlearlshsripeiQAELSKLEEEVSRIEarlreIEQKLNRltlekeyLEKEIQELQEQRIDLKEQIKSIEKEIEnl 859
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1952 KARSEELMNMFEDKEKINMTL-AELPDLVEQCQNITLLYSQLIDEYDE--EYVQTAGRHAEKLEVQAQKIVDRFvdtrTE 2028
Cdd:TIGR02169 860 NGKKEELEEELEELEAALRDLeSRLGDLKKERDELEAQLRELERKIEEleAQIEKKRKRLSELKAKLEALEEEL----SE 935
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2029 TENPLKA---SHAYENIVEALKNATEAVDSAAEASEAVSkMLGSEGSESGDANEESLRSQLEKLKnesslsnvdnsnavk 2105
Cdd:TIGR02169 936 IEDPKGEdeeIPEEELSLEDVQAELQRVEEEIRALEPVN-MLAIQEYEEVLKRLDELKEKRAKLE--------------- 999
|
330 340
....*....|....*....|....*.
gi 25145020 2106 iveelkKEKKDLTDRLGHLNELKTSI 2131
Cdd:TIGR02169 1000 ------EERKAILERIEEYEKKKREV 1019
|
|
| 235kDa-fam |
TIGR01612 |
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in ... |
1869-2258 |
6.25e-06 |
|
reticulocyte binding/rhoptry protein; This model represents a group of paralogous families in plasmodium species alternately annotated as reticulocyte binding protein, 235-kDa family protein and rhoptry protein. Rhoptry protein is localized on the cell surface and is extremely large (although apparently lacking in repeat structure) and is important for the process of invasion of the RBCs by the parasite. These proteins are found in P. falciparum, P. vivax and P. yoelii.
Pssm-ID: 130673 [Multi-domain] Cd Length: 2757 Bit Score: 52.36 E-value: 6.25e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1869 VTAQKLNETIfEDLKNRIDVLEQwmNDYRET-IYDVSK---KDTADAER--------MSLV-----------VGKRINRY 1925
Cdd:TIGR01612 1291 IISKKHDENI-SDIREKSLKIIE--DFSEESdINDIKKelqKNLLDAQKhnsdinlyLNEIaniynilklnkIKKIIDEV 1367
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1926 KEVSNEIEKLRVEAEDQIAYSRNSIEKARseELMNMFEDKEKINMTLAElPDLVEQCQNITLLYSQLIDEY--DEEYVQT 2003
Cdd:TIGR01612 1368 KEYTKEIEENNKNIKDELDKSEKLIKKIK--DDINLEECKSKIESTLDD-KDIDECIKKIKELKNHILSEEsnIDTYFKN 1444
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2004 AGRHAEKLEVQAQKIvdRFVDTRTE-----TENPLKASHAY------ENIVEALKNATEAvDSAAEASEAvSKMLGSEGS 2072
Cdd:TIGR01612 1445 ADENNENVLLLFKNI--EMADNKSQhilkiKKDNATNDHDFninelkEHIDKSKGCKDEA-DKNAKAIEK-NKELFEQYK 1520
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2073 ES-----GDANEESLRSQLEKLKNESSLsnvdnsnavkIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEASSwDD 2147
Cdd:TIGR01612 1521 KDvtellNKYSALAIKNKFAKTKKDSEI----------IIKEIKDAHKKFILEAEKSEQKIKEIKKEKFRIEDDAAK-ND 1589
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2148 KHDR----MHSILKNgAKTAHERSANVKKESEGIKTEVSAIKAEVEKL-MNSTSSGVQEDMEKIRASRTGMEygaqKLTK 2222
Cdd:TIGR01612 1590 KSNKaaidIQLSLEN-FENKFLKISDIKKKINDCLKETESIEKKISSFsIDSQDTELKENGDNLNSLQEFLE----SLKD 1664
|
410 420 430
....*....|....*....|....*....|....*.
gi 25145020 2223 VNKLSTANQGRTDKMARNIAILKAKIEQaREKAYQI 2258
Cdd:TIGR01612 1665 QKKNIEDKKKELDELDSEIEKIEIDVDQ-HKKNYEI 1699
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1833-2259 |
6.65e-06 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 52.45 E-value: 6.65e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAH------LNATVERGEYVEKRLNRA----QQEHKKAEELLKMVTAQKLNETIFEDLKNRIDvleqwmnDYREtIYD 1902
Cdd:PTZ00121 1061 EAKAHvgqdegLKPSYKDFDFDAKEDNRAdeatEEAFGKAEEAKKTETGKAEEARKAEEAKKKAE-------DARK-AEE 1132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1903 VSKKDTA----DAERMSLVVGKRINRYKEVSNEIEKLRvEAED--QIAYSRNSIEKARSEELMNMfEDKEKInmtlaELP 1976
Cdd:PTZ00121 1133 ARKAEDArkaeEARKAEDAKRVEIARKAEDARKAEEAR-KAEDakKAEAARKAEEVRKAEELRKA-EDARKA-----EAA 1205
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1977 DLVEQCQNItllysQLIDEYDEEYVQTAGRHAEKLEVQAQKIvdrfvdTRTETENPLKASHAYENIVEALKNATEAVDSA 2056
Cdd:PTZ00121 1206 RKAEEERKA-----EEARKAEDAKKAEAVKKAEEAKKDAEEA------KKAEEERNNEEIRKFEEARMAHFARRQAAIKA 1274
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2057 AEASEAvskmlgsegsesgdaneESLRSQLEKLKNESslsnVDNSNAVKIVEELKK--EKKDLTDRLGHLNELKTSIVKR 2134
Cdd:PTZ00121 1275 EEARKA-----------------DELKKAEEKKKADE----AKKAEEKKKADEAKKkaEEAKKADEAKKKAEEAKKKADA 1333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2135 LGVIKNEASSWDDKHDRMHSILKNGAKTAHER--SANVKKESEGIKTEVSAIKAEVEKLMNSTSSGVQED------MEKI 2206
Cdd:PTZ00121 1334 AKKKAEEAKKAAEAAKAEAEAAADEAEAAEEKaeAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDkkkadeLKKA 1413
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 2207 RASRTGMEYGAQKLTKVNKL----STANQGRTDKMARNIAILKAKIEQAREKAYQIR 2259
Cdd:PTZ00121 1414 AAAKKKADEAKKKAEEKKKAdeakKKAEEAKKADEAKKKAEEAKKAEEAKKKAEEAK 1470
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1540-1583 |
7.09e-06 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 45.42 E-value: 7.09e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 25145020 1540 CSCHGH---SQTCNPDTSVCtDCEHNTFGDFCEHCLPGYIGDAREGG 1583
Cdd:pfam00053 1 CDCNPHgslSDTCDPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1827-2096 |
1.31e-05 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 49.91 E-value: 1.31e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1827 LDGMLMEAEAH------LNATVErgEYVEKR--LNRAQQEHK-KAEELLKMVtaQKLNETIFEdLKNRIDVLEQWMNDYR 1897
Cdd:COG1340 17 IEELREEIEELkekrdeLNEELK--ELAEKRdeLNAQVKELReEAQELREKR--DELNEKVKE-LKEERDELNEKLNELR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1898 ETIYDVSKK-DTADAERMSL-VVGKRINR--YKEvsnEIEKLRVEAEDQIaysrnsIEKARS-----EELMNMFEDKEKI 1968
Cdd:COG1340 92 EELDELRKElAELNKAGGSIdKLRKEIERleWRQ---QTEVLSPEEEKEL------VEKIKElekelEKAKKALEKNEKL 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1969 NMTLAELPDLVEQCQNITLL---YSQLIDEYDEEyVQTAGRHAEKLEVQAQKIVDRFVDTRTETEnplKASHAYENIVEA 2045
Cdd:COG1340 163 KELRAELKELRKEAEEIHKKikeLAEEAQELHEE-MIELYKEADELRKEADELHKEIVEAQEKAD---ELHEEIIELQKE 238
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 2046 LKNATEAVDSAAEASEAVSKmlgsegsesgDANEESLRSQ----LEKLKNESSLS 2096
Cdd:COG1340 239 LRELRKELKKLRKKQRALKR----------EKEKEELEEKaeeiFEKLKKGEKLT 283
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1226-1282 |
1.61e-05 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 44.27 E-value: 1.61e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 1226 PCGCNAAGTDPLQCKDGQclcneiGECPCKKNVHGTKCDQCGEGTFSlDSSNLKGCT 1282
Cdd:cd00055 1 PCDCNGHGSLSGQCDPGT------GQCECKPNTTGRRCDRCAPGYYG-LPSQGGGCQ 50
|
|
| Mplasa_alph_rch |
TIGR04523 |
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of ... |
1849-2207 |
1.67e-05 |
|
helix-rich Mycoplasma protein; Members of this family occur strictly within a subset of Mycoplasma species. Members average 750 amino acids in length, including signal peptide. Sequences are predicted (Jpred 3) to be almost entirely alpha-helical. These sequences show strong periodicity (consistent with long alpha helical structures) and low complexity rich in D,E,N,Q, and K. Genes encoding these proteins are often found in tandem. The function is unknown.
Pssm-ID: 275316 [Multi-domain] Cd Length: 745 Bit Score: 50.79 E-value: 1.67e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1849 EKRLNRAQQEHKKAEELLKMVTAQKlnetifEDLKNRIDVLEQWMNDYRETIYDVSKKDTAdaermslvvgkrinryKEV 1928
Cdd:TIGR04523 397 ESKIQNQEKLNQQKDEQIKKLQQEK------ELLEKEIERLKETIIKNNSEIKDLTNQDSV----------------KEL 454
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1929 S-NEIEKLRVEAEDQIAYSRNSIEKARS--EELMNMFEDKEK-INMTLAELPDLVEQCQNITllysQLIDEYDEEyvqta 2004
Cdd:TIGR04523 455 IiKNLDNTRESLETQLKVLSRSINKIKQnlEQKQKELKSKEKeLKKLNEEKKELEEKVKDLT----KKISSLKEK----- 525
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2005 grhAEKLEVQAQKIVDRFVDTRTE--------TENPLKAS--HAYENIVEaLKNATEAVDSAAEASEAVSKMLGSEGSEs 2074
Cdd:TIGR04523 526 ---IEKLESEKKEKESKISDLEDElnkddfelKKENLEKEidEKNKEIEE-LKQTQKSLKKKQEEKQELIDQKEKEKKD- 600
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2075 gdaneesLRSQLEKlkNESSLSNVDnsnavKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEasswddkhdrmhs 2154
Cdd:TIGR04523 601 -------LIKEIEE--KEKKISSLE-----KELEKAKKENEKLSSIIKNIKSKKNKLKQEVKQIKET------------- 653
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 25145020 2155 ilkngAKTAHERSANVKKESEGIKTEVSAIKAEVEKLMNSTSSGVQEDM-EKIR 2207
Cdd:TIGR04523 654 -----IKEIRNKWPEIIKKIKESKTKIDDIIELMKDWLKELSLHYKKYItRMIR 702
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
478-525 |
2.43e-05 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 43.84 E-value: 2.43e-05
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|
gi 25145020 478 CPCNRAGSVNfDTCDGAS--CQCKANVEGIYCDRCKAGTIHlsaSNPLGC 525
Cdd:smart00180 1 CDCDPGGSAS-GTCDPDTgqCECKPNVTGRRCDRCAPGYYG---DGPPGC 46
|
|
| PTZ00121 |
PTZ00121 |
MAEBL; Provisional |
1849-2254 |
4.14e-05 |
|
MAEBL; Provisional
Pssm-ID: 173412 [Multi-domain] Cd Length: 2084 Bit Score: 49.75 E-value: 4.14e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1849 EKRlnRAQQEHKKAEELLKMVTAQKLNETifedlKNRIDVLEQWMNDYRETiyDVSKKDTADAERMSlvvgKRINRYKEV 1928
Cdd:PTZ00121 1442 EAK--KADEAKKKAEEAKKAEEAKKKAEE-----AKKADEAKKKAEEAKKA--DEAKKKAEEAKKKA----DEAKKAAEA 1508
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1929 SNEIEKLRVEAEDQIAYSRNSIEKARSEELMNMFEDKEKIN-------MTLAELPDLVEQCQNitllysqlideyDEEYV 2001
Cdd:PTZ00121 1509 KKKADEAKKAEEAKKADEAKKAEEAKKADEAKKAEEKKKADelkkaeeLKKAEEKKKAEEAKK------------AEEDK 1576
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2002 QTAGRHAEKLEvQAQKIVDRFVDTRTETENPLKAshayenivEALKNATEAVDSAAEASEAvskmlgsegSESGDANEES 2081
Cdd:PTZ00121 1577 NMALRKAEEAK-KAEEARIEEVMKLYEEEKKMKA--------EEAKKAEEAKIKAEELKKA---------EEEKKKVEQL 1638
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2082 LRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDltdrlghlnelktsivKRLGvikNEASSWDDKHDRMHSILKNGAK 2161
Cdd:PTZ00121 1639 KKKEAEEKKKAEELKKAEEENKIKAAEEAKKAEED----------------KKKA---EEAKKAEEDEKKAAEALKKEAE 1699
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2162 TAHERSANVKKESEGIKTEVSAIKAEVEKLMNSTSSGVQEDMEKIRASRTGMEYGAQKltKVNKLSTANQGRTDKMARNI 2241
Cdd:PTZ00121 1700 EAKKAEELKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEKK--KIAHLKKEEEKKAEEIRKEK 1777
|
410
....*....|....
gi 25145020 2242 -AILKAKIEQAREK 2254
Cdd:PTZ00121 1778 eAVIEEELDEEDEK 1791
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1841-2255 |
4.19e-05 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 49.83 E-value: 4.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1841 TVERGEYVEKRLNRAQQEHKK--AEELLKMVTAQ-KLNETIFEDLKNRIDVLEQWMNDyretiydVSKKDTADAERMSLV 1917
Cdd:PTZ00440 1148 NMNLEDITLNEVNEIEIEYERilIDHIVEQINNEaKKSKTIMEEIESYKKDIDQVKKN-------MSKERNDHLTTFEYN 1220
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1918 VGKriNRYKEVSNEIEKLRVEAEDQIAYSRNS--------IEKARSEELMNMFEDKEKINMTLAELPDLVEqcqnitLLY 1989
Cdd:PTZ00440 1221 AYY--DKATASYENIEELTTEAKGLKGEANRStnvdelkeIKLQVFSYLQQVIKENNKMENALHEIKNMYE------FLI 1292
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1990 SQLIDEYDEEYVQTAGRhAEKLEVQAQKIVDRFVDTRTETENPLKASHAYEN-IVEALKNatEAVDSAAEASEAVSKmlg 2068
Cdd:PTZ00440 1293 SIDSEKILKEILNSTKK-AEEFSNDAKKELEKTDNLIKQVEAKIEQAKEHKNkIYGSLED--KQIDDEIKKIEQIKE--- 1366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2069 sEGSESGDANEESLrSQLEKLKnESSLSNVDNSNAVKIVEELKKEKKDLTDR------LGHLNELKTSIVKRLGVIKNEA 2142
Cdd:PTZ00440 1367 -EISNKRKEINKYL-SNIKSNK-EKCDLHVRNASRGKDKIDFLNKHEAIEPSnskevnIIKITDNINKCKQYSNEAMETE 1443
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2143 SSWDDKHDRMH-------SILKNGAKTAHE-RSANVKKES----EGIKTEVSAIKAEVEKLmnstssgvQEDMEKIRA-- 2208
Cdd:PTZ00440 1444 NKADENNDSIIkyekeitNILNNSSILGKKtKLEKKKKEAtnimDDINGEHSIIKTKLTKS--------SEKLNQLNEqp 1515
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 25145020 2209 --SRTGMEYGAQKLTKVNKLSTANQGRTDKMARNIAILKAKIEQAREKA 2255
Cdd:PTZ00440 1516 niKREGDVLNNDKSTIAYETIQYNLGRVKHNLLNILNIKDEIETILNKA 1564
|
|
| CwlO1 |
COG3883 |
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function ... |
1833-2077 |
5.80e-05 |
|
Uncharacterized N-terminal coiled-coil domain of peptidoglycan hydrolase CwlO [Function unknown];
Pssm-ID: 443091 [Multi-domain] Cd Length: 379 Bit Score: 48.29 E-value: 5.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVERGEYVEKRLNRAQQEHKKAEEllKMVTAQKLNETIFEDLKNRIDVLEQWMNDYRETIYDVSK------- 1905
Cdd:COG3883 34 AAQAELDALQAELEELNEEYNELQAELEALQA--EIDKLQAEIAEAEAEIEERREELGERARALYRSGGSVSYldvllgs 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1906 KDTADA-ERMSLVvgKRINRY-KEVSNEIEKLRVEAEDQiaysRNSIEKARSEelmnMFEDKEKINMTLAELPDLVEQCQ 1983
Cdd:COG3883 112 ESFSDFlDRLSAL--SKIADAdADLLEELKADKAELEAK----KAELEAKLAE----LEALKAELEAAKAELEAQQAEQE 181
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1984 NitlLYSQLIDEYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASEAV 2063
Cdd:COG3883 182 A---LLAQLSAEEAAAEAQLAELEAELAAAEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASAAGAGAAGAAGAA 258
|
250
....*....|....
gi 25145020 2064 SKMLGSEGSESGDA 2077
Cdd:COG3883 259 AGSAGAAGAAAGAA 272
|
|
| DUF1978 |
pfam09321 |
Domain of unknown function (DUF1978); Members of this family are found in various hypothetical ... |
1883-2128 |
8.96e-05 |
|
Domain of unknown function (DUF1978); Members of this family are found in various hypothetical proteins produced by the bacterium Chlamydia pneumoniae. Their exact function has not, as yet, been identified.
Pssm-ID: 312723 [Multi-domain] Cd Length: 244 Bit Score: 46.84 E-value: 8.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1883 KNRIDVLEQWMnDYRETIYDVSKKDTADAERMSLVVGKRINRYKEVSNEI-------EKLRVE-AEDQIAYSRNSIEKAR 1954
Cdd:pfam09321 11 KEFREMLERLS-DYRKVVFWLSENGVIDLPNDPGKWGLSGIPCRDALSEIsrhelweKKAHLKhLESLYTQARDRFEKQS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1955 SEELMNMFEDKEKinmtlaELPDLVEqcqnitllysqliDEYDEEyVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLK 2034
Cdd:pfam09321 90 SKKNQKELEEAEQ------EYLSSWE-------------DVKDQE-IERVQERLQALQALYPEVSVSEEETEGQETVTPT 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2035 AS--HAYENIVEALKNATEAVDSAAEASEAVSKMLGSEGSESG-DANEESLRSQLEKLKNESSlsnvdnsnavKIVEELK 2111
Cdd:pfam09321 150 VDleTALGRIEESYRECVRDQEDYWKEEESKEVEMSAEFREEGgKKKSEEFQEQLGSLERFLK----------EHSEELE 219
|
250
....*....|....*..
gi 25145020 2112 KEKKDLtdrLGHLNELK 2128
Cdd:pfam09321 220 VLEKHI---LKHESEAT 233
|
|
| 46 |
PHA02562 |
endonuclease subunit; Provisional |
1874-2163 |
1.01e-04 |
|
endonuclease subunit; Provisional
Pssm-ID: 222878 [Multi-domain] Cd Length: 562 Bit Score: 48.09 E-value: 1.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1874 LNETIfEDLKNRIDVLEQWMNDYRETIYDVSKKDTADAERMSLVVGKRINRYKEVSNEIEklrvEAEDQIAYSRNSIEKa 1953
Cdd:PHA02562 179 LNQQI-QTLDMKIDHIQQQIKTYNKNIEEQRKKNGENIARKQNKYDELVEEAKTIKAEIE----ELTDELLNLVMDIED- 252
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1954 RSEELmnmfedkEKINMTLAELPDLVEQCQNITLLY---------SQLIDEYDEeyvqtagrhaeKLEVQAQKIVDrfvd 2024
Cdd:PHA02562 253 PSAAL-------NKLNTAAAKIKSKIEQFQKVIKMYekggvcptcTQQISEGPD-----------RITKIKDKLKE---- 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2025 trtetenplkASHAYENIVEALKNATEAVDSAAEASEAVSkmlgsegsesgdaneeSLRSQLEKLKNESSLSNVDNSNAV 2104
Cdd:PHA02562 311 ----------LQHSLEKLDTAIDELEEIMDEFNEQSKKLL----------------ELKNKISTNKQSLITLVDKAKKVK 364
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2105 KIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEAsswdDKHDRMHSILK-NGAKTA 2163
Cdd:PHA02562 365 AAIEELQAEFVDNAEELAKLQDELDKIVKTKSELVKEK----YHRGIVTDLLKdSGIKAS 420
|
|
| COG4372 |
COG4372 |
Uncharacterized protein, contains DUF3084 domain [Function unknown]; |
1833-2135 |
1.15e-04 |
|
Uncharacterized protein, contains DUF3084 domain [Function unknown];
Pssm-ID: 443500 [Multi-domain] Cd Length: 370 Bit Score: 47.20 E-value: 1.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLKmVTAQKLNETI--FEDLKNRIDVLEQWMNDYRETIYDVSK-KDTA 1909
Cdd:COG4372 49 QLREELEQAREELEQLEEELEQARSELEQLEEELE-ELNEQLQAAQaeLAQAQEELESLQEEAEELQEELEELQKeRQDL 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1910 DAERMSL---------VVGKRINRYKEVSNEIEKLRVEAEDQIAYSRNSIEKARSEELMNMFEDKEKINMTLAELPDLVE 1980
Cdd:COG4372 128 EQQRKQLeaqiaelqsEIAEREEELKELEEQLESLQEELAALEQELQALSEAEAEQALDELLKEANRNAEKEEELAEAEK 207
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1981 ----QCQNITLLYSQLIDEYDEEYVQTAGRHAEKLEVQAQK-IVDRFVDTRTETENPLKASHAYENIVEALKNAT---EA 2052
Cdd:COG4372 208 liesLPRELAEELLEAKDSLEAKLGLALSALLDALELEEDKeELLEEVILKEIEELELAILVEKDTEEEELEIAAlelEA 287
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2053 VDSAAEASEAVSKMLGSEGSESGDANEESLRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGHLNELKTSIV 2132
Cdd:COG4372 288 LEEAALELKLLALLLNLAALSLIGALEDALLAALLELAKKLELALAILLAELADLLQLLLVGLLDNDVLELLSKGAEAGV 367
|
...
gi 25145020 2133 KRL 2135
Cdd:COG4372 368 ADG 370
|
|
| HEC1 |
COG5185 |
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell ... |
1869-2261 |
1.20e-04 |
|
Chromosome segregation protein NDC80, interacts with SMC proteins [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 444066 [Multi-domain] Cd Length: 594 Bit Score: 47.64 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1869 VTAQKLNETIFEDLKNRI-DVLEQWMNdyRETIYDVSKKDTADAERMSLVVgkriNRYKEVSNEIEKLRVEAEDQiaysr 1947
Cdd:COG5185 204 VNSIKESETGNLGSESTLlEKAKEIIN--IEEALKGFQDPESELEDLAQTS----DKLEKLVEQNTDLRLEKLGE----- 272
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1948 nsiekarSEELMnmfedkEKINMTLAELPDLVEQCQnitllysQLIDEYDEEyvQTAGRHAEKLEVQAQK--IVDRFVDT 2025
Cdd:COG5185 273 -------NAESS------KRLNENANNLIKQFENTK-------EKIAEYTKS--IDIKKATESLEEQLAAaeAEQELEES 330
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2026 RTETENPLKAshAYENIVEALKNATEAVdsaAEASEAVSKMLGSEGSESGDANEESLRSQLEKLKNESSLSNVDNSNAVK 2105
Cdd:COG5185 331 KRETETGIQN--LTAEIEQGQESLTENL---EAIKEEIENIVGEVELSKSSEELDSFKDTIESTKESLDEIPQNQRGYAQ 405
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2106 -IVEELKKEKKDLTDRLGHLN---ELKTSIVKRLGVIKNEASSwddkhdrmhSILKNGAKTAHERSANVKKESEGIKTEV 2181
Cdd:COG5185 406 eILATLEDTLKAADRQIEELQrqiEQATSSNEEVSKLLNELIS---------ELNKVMREADEESQSRLEEAYDEINRSV 476
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2182 SAIKAEVEKLMNSTSSGVQEDMEKIRASRTGMEygaQKLTKVNKLSTANQGRTDKMARniailKAKIEQAREKAYQIRLS 2261
Cdd:COG5185 477 RSKKEDLNEELTQIESRVSTLKATLEKLRAKLE---RQLEGVRSKLDQVAESLKDFMR-----ARGYAHILALENLIPAS 548
|
|
| Laminin_II |
pfam06009 |
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 ... |
2157-2286 |
1.21e-04 |
|
Laminin Domain II; It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 368703 [Multi-domain] Cd Length: 138 Bit Score: 44.40 E-value: 1.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2157 KNGAKTAHERSANVKKESEGIKTEVSAIKAEVEKLMNS---TSSGVQEDMEKIRASRTGMeygaQKLTK-----VNKLST 2228
Cdd:pfam06009 2 KELAREANETAKEVLEQLAPLSQNLENTSEKLSGINRSleeTNELVNDANKALDDAGRSV----KKLEElapdlLDKLKP 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2229 ANQGR--TDKMARNIAILKAKIEQAREKAYQIRLSLNSGerGLCKRSYISPASPSPVNTF 2286
Cdd:pfam06009 78 LKQLEvnSSSLSDNISRIKELIAQARKAANSIKVSVSFD--GDSIVELRPPISVTDLAAY 135
|
|
| PRK02224 |
PRK02224 |
DNA double-strand break repair Rad50 ATPase; |
1831-2092 |
1.57e-04 |
|
DNA double-strand break repair Rad50 ATPase;
Pssm-ID: 179385 [Multi-domain] Cd Length: 880 Bit Score: 47.73 E-value: 1.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGE---YVEKRLNRAQQEHKKAEELL--KMVTAQKLNETIfEDLKNRIDVLEQWMNDYRETIYDvsK 1905
Cdd:PRK02224 487 LEEEVEEVEERLERAEdlvEAEDRIERLEERREDLEELIaeRRETIEEKRERA-EELRERAAELEAEAEEKREAAAE--A 563
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1906 KDTADAERMSLvvgKRINRYK-EVSNEIEKLR--VEAEDQIAYSRNSIEKARsEELMNMFEDKEKINMTLAELPDLVeqc 1982
Cdd:PRK02224 564 EEEAEEAREEV---AELNSKLaELKERIESLEriRTLLAAIADAEDEIERLR-EKREALAELNDERRERLAEKRERK--- 636
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1983 qnitllySQLIDEYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLKASHAYENIVE----------ALKNATEA 2052
Cdd:PRK02224 637 -------RELEAEFDEARIEEAREDKERAEEYLEQVEEKLDELREERDDLQAEIGAVENELEeleelrerreALENRVEA 709
|
250 260 270 280
....*....|....*....|....*....|....*....|
gi 25145020 2053 VDSAAEASEAVSKMLGSEGSESGDANEEslrsQLEKLKNE 2092
Cdd:PRK02224 710 LEALYDEAEELESMYGDLRAELRQRNVE----TLERMLNE 745
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
889-932 |
2.67e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.76 E-value: 2.67e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 889 CTCN--GNIDPmgigNCDSETGKCLkCIGHTTGDSCESCKEHHWGN 932
Cdd:smart00180 1 CDCDpgGSASG----TCDPDTGQCE-CKPNVTGRRCDRCAPGYYGD 41
|
|
| rad50 |
TIGR00606 |
rad50; All proteins in this family for which functions are known are involvedin recombination, ... |
1831-2197 |
2.71e-04 |
|
rad50; All proteins in this family for which functions are known are involvedin recombination, recombinational repair, and/or non-homologous end joining.They are components of an exonuclease complex with MRE11 homologs. This family is distantly related to the SbcC family of bacterial proteins.This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University).
Pssm-ID: 129694 [Multi-domain] Cd Length: 1311 Bit Score: 46.96 E-value: 2.71e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1831 LMEAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLKMVtaQKLNETI--FEDLKNRIDVLEQWMNDYRETIYDVSKKDT 1908
Cdd:TIGR00606 226 ITSKEAQLESSREIVKSYENELDPLKNRLKEIEHNLSKI--MKLDNEIkaLKSRKKQMEKDNSELELKMEKVFQGTDEQL 303
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1909 ADAERMSLVVGKRINRYK-EVSNEIEKLRVE--------AEDQIAYSRNSIEKARSEELMNMFEDKEKINMTLAEL---- 1975
Cdd:TIGR00606 304 NDLYHNHQRTVREKERELvDCQRELEKLNKErrllnqekTELLVEQGRLQLQADRHQEHIRARDSLIQSLATRLELdgfe 383
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1976 --PDLVEQCQNitllYSQLIDEYDEEYVQTAGRHAEKL---EVQAQKIVDRFVDTRT--------ETENPLKASHAYENI 2042
Cdd:TIGR00606 384 rgPFSERQIKN----FHTLVIERQEDEAKTAAQLCADLqskERLKQEQADEIRDEKKglgrtielKKEILEKKQEELKFV 459
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2043 VEALKNATEAVDSAAEASEAVSKMLGSEGSESGDANEESLRSQLEKLKNES-----SLSNVDNSNavkivEELKKEKKDL 2117
Cdd:TIGR00606 460 IKELQQLEGSSDRILELDQELRKAERELSKAEKNSLTETLKKEVKSLQNEKadldrKLRKLDQEM-----EQLNHHTTTR 534
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2118 TDRLgHLNELKTSIVKRLGVIKNEASS----------WDDK-HDRMHSiLKNGAKTAHERSANVKKESEGIKTEVSAIKA 2186
Cdd:TIGR00606 535 TQME-MLTKDKMDKDEQIRKIKSRHSDeltsllgyfpNKKQlEDWLHS-KSKEINQTRDRLAKLNKELASLEQNKNHINN 612
|
410
....*....|.
gi 25145020 2187 EVEKLMNSTSS 2197
Cdd:TIGR00606 613 ELESKEEQLSS 623
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1133-1179 |
2.87e-04 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 40.80 E-value: 2.87e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1133 ECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAWDYHPL-NGCK 1179
Cdd:cd00055 3 DCNGHGSLSGQCDPGTGQCECKPNTTGRRCDRCAPGYYGLPSQgGGCQ 50
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1590-1644 |
3.12e-04 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 40.80 E-value: 3.12e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCnSCKPGYTGQYCETCVAGYYGDPQHIGGTC 1644
Cdd:pfam00053 1 CDCNPH-GSLSDTC----DPETGQC-LCKPGVTGRHCDRCKPGYYGLPSDPPQGC 49
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
296-339 |
3.52e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 40.37 E-value: 3.52e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*..
gi 25145020 296 CICY--GHA-ESCpsDPVTGQfkCECRHNTCGESCNRCCPLFNQLPW 339
Cdd:smart00180 1 CDCDpgGSAsGTC--DPDTGQ--CECKPNVTGRRCDRCAPGYYGDGP 43
|
|
| COG1340 |
COG1340 |
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown]; |
1849-1975 |
3.53e-04 |
|
Uncharacterized coiled-coil protein, contains DUF342 domain [Function unknown];
Pssm-ID: 440951 [Multi-domain] Cd Length: 297 Bit Score: 45.29 E-value: 3.53e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1849 EKRLNRAQQEHKKAEELLKMVT----------------------AQKLNETIFEdLKNRIDVLEQWMNDYRETIydVSKK 1906
Cdd:COG1340 146 EKELEKAKKALEKNEKLKELRAelkelrkeaeeihkkikelaeeAQELHEEMIE-LYKEADELRKEADELHKEI--VEAQ 222
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25145020 1907 DTADAERmslvvgkriNRYKEVSNEIEKLRVEAEDQIAYSRN-------SIEKARSEELMNMFEDKEKinMTLAEL 1975
Cdd:COG1340 223 EKADELH---------EEIIELQKELRELRKELKKLRKKQRAlkrekekEELEEKAEEIFEKLKKGEK--LTTEEL 287
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
296-342 |
4.48e-04 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 40.41 E-value: 4.48e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 296 CICYGHAESCPS-DPVTGQfkCECRHNTCGESCNRCCPLFNQLPWKPG 342
Cdd:pfam00053 1 CDCNPHGSLSDTcDPETGQ--CLCKPGVTGRHCDRCKPGYYGLPSDPP 46
|
|
| VSP |
pfam03302 |
Giardia variant-specific surface protein; |
821-1159 |
4.85e-04 |
|
Giardia variant-specific surface protein;
Pssm-ID: 146106 [Multi-domain] Cd Length: 397 Bit Score: 45.35 E-value: 4.85e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 821 ACEQCEcPSLDLNPNPECIST--ELAVLGSVASNEDNYVCINCPLGY-----EGNKCEYCSDGFFEDPLTGKCIECTCNG 893
Cdd:pfam03302 38 VCEECN-SNNYLTPTSQCIDDcaKIGNYYYTTNANNKKICKECTVANcktceDQGQCQACNDGFYKSGDACSPCHESCKT 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 894 NIDPMGIGNCDSETGKCLKCIGHTTGDSC-ESCKEHHWGNAqlhtCKPCGCHTQGAvnPQCSE--------ENGECECKE 964
Cdd:pfam03302 117 CSGGTASDCTECLTGKALRYGNDGTKGTCgEGCTTGTGAGA----CKTCGLTIDGT--SYCSEcateteypQNGVCTSTA 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 965 NYIGAQCdrckeNHGDVENG-CPACdCNDTGSIGSDCDQVS---GQCNCKQGVFGKQCDQCRPSYfnftdagcqfchcni 1040
Cdd:pfam03302 191 ARATATC-----KASSVANGmCSSC-ANGYFRMNGGCYETTkfpGKSVCEEANSGGTCQKEAPGY--------------- 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1041 ygSIEDGkcDQTTGKCECRENVEGTMCEKCADGYFNITsgDGCEDCgcdptgseDVSCNLVTGQCVckpgvtglKCDSCL 1120
Cdd:pfam03302 250 --KLNNG--DLVTCSPGCKTCTSNTVCTTCMDGYVKTS--DSCTKC--------DSSCETCTGATT--------TCKTCA 307
|
330 340 350 360
....*....|....*....|....*....|....*....|.
gi 25145020 1121 PNFY--GLTSEGCTECEPCPAPGQVCDPIdgSCVCPPNTVG 1159
Cdd:pfam03302 308 TGYYksGTGCVSCTSSESDNGITGVKGCL--NCAPPSNNKG 346
|
|
| Laminin_I |
pfam06008 |
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from ... |
1826-1955 |
5.17e-04 |
|
Laminin Domain I; coiled-coil structure. It has been suggested that the domains I and II from laminin A, B1 and B2 may come together to form a triple helical coiled-coil structure.
Pssm-ID: 310534 [Multi-domain] Cd Length: 258 Bit Score: 44.71 E-value: 5.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1826 ALDGMLMEAEAHLNATVERGEYVEKRLnrAQQEHKKAEELLKMV-----TAQKLNETIFEDLKNRIDVLEQWMNDYRETI 1900
Cdd:pfam06008 119 DLSRMLAEAQRMLGEIRSRDFGTQLQN--AEAELKAAQDLLSRIqtwfqSPQEENKALANALRDSLAEYEAKLSDLRELL 196
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 25145020 1901 YDVSKKdTADAERMSLVVGKRINRYKEVSNEIEKLRVEAEDQIAYSRNSIEKARS 1955
Cdd:pfam06008 197 REAAAK-TRDANRLNLANQANLREFQRKKEEVSEQKNQLEETLKTARDSLDAANL 250
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1227-1271 |
5.21e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.99 E-value: 5.21e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 25145020 1227 CGCNAAGTDPLQCKdgqclcNEIGECPCKKNVHGTKCDQCGEGTF 1271
Cdd:smart00180 1 CDCDPGGSASGTCD------PDTGQCECKPNVTGRRCDRCAPGYY 39
|
|
| Laminin_G_2 |
pfam02210 |
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G ... |
2291-2372 |
5.77e-04 |
|
Laminin G domain; This family includes the Thrombospondin N-terminal-like domain, a Laminin G subfamily.
Pssm-ID: 460494 [Multi-domain] Cd Length: 126 Bit Score: 42.41 E-value: 5.77e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2291 RPLQqvSDAVILVSKTKGrrtqpSEHLAVEIRDKRVVVHWDIGSGKKMITNSHpinyVPSNDRvTWYHIDVLRIGNAVNL 2370
Cdd:pfam02210 2 RTRQ--PNGLLLYAGGGG-----SDFLALELVNGRLVLRYDLGSGPESLLSSG----KNLNDG-QWHSVRVERNGNTLTL 69
|
..
gi 25145020 2371 TV 2372
Cdd:pfam02210 70 SV 71
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1590-1637 |
6.10e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.99 E-value: 6.10e-04
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCNsCKPGYTGQYCETCVAGYYGDP 1637
Cdd:smart00180 1 CDCDPG-GSASGTC----DPDTGQCE-CKPNVTGRRCDRCAPGYYGDG 42
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
1590-1642 |
6.68e-04 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 40.03 E-value: 6.68e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|...
gi 25145020 1590 CACPLVeNSFSDSCvavdHGRGYVCnSCKPGYTGQYCETCVAGYYGDPQHIGG 1642
Cdd:cd00055 2 CDCNGH-GSLSGQC----DPGTGQC-ECKPNTTGRRCDRCAPGYYGLPSQGGG 48
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
384-411 |
9.05e-04 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 39.22 E-value: 9.05e-04
10 20
....*....|....*....|....*...
gi 25145020 384 GGRClECAHNTEGFNCERCKDGYYRPSG 411
Cdd:smart00180 17 TGQC-ECKPNVTGRRCDRCAPGYYGDGP 43
|
|
| SMC_prok_A |
TIGR02169 |
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of ... |
1993-2259 |
1.07e-03 |
|
chromosome segregation protein SMC, primarily archaeal type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]
Pssm-ID: 274009 [Multi-domain] Cd Length: 1164 Bit Score: 45.06 E-value: 1.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1993 IDEYDE------EYVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLKashaYENIVEALKNAteavdsaaEASEAVSKM 2066
Cdd:TIGR02169 165 VAEFDRkkekalEELEEVEENIERLDLIIDEKRQQLERLRREREKAER----YQALLKEKREY--------EGYELLKEK 232
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2067 LGSEGS-ESGDANEESLRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDrlGHLNELKTSIVKRLGVIKNEASSW 2145
Cdd:TIGR02169 233 EALERQkEAIERQLASLEEELEKLTEEISELEKRLEEIEQLLEELNKKIKDLGE--EEQLRVKEKIGELEAEIASLERSI 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2146 DDKHDRMHSILKNGAKTAHERSaNVKKESEGIKTEVSAIKAEVEKLMNSTSSgVQEDMEKIRAsrtgmeygaqkltKVNK 2225
Cdd:TIGR02169 311 AEKERELEDAEERLAKLEAEID-KLLAEIEELEREIEEERKRRDKLTEEYAE-LKEELEDLRA-------------ELEE 375
|
250 260 270
....*....|....*....|....*....|....
gi 25145020 2226 LSTANQGRTDKMARniaiLKAKIEQAREKAYQIR 2259
Cdd:TIGR02169 376 VDKEFAETRDELKD----YREKLEKLKREINELK 405
|
|
| EGF_Lam |
smart00180 |
Laminin-type epidermal growth factor-like domai; |
1136-1178 |
1.29e-03 |
|
Laminin-type epidermal growth factor-like domai;
Pssm-ID: 214543 Cd Length: 46 Bit Score: 38.83 E-value: 1.29e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1136 PCPAPGQV---CDPIDGSCVCPPNTVGEMCENCTTNAWDYHPlNGC 1178
Cdd:smart00180 2 DCDPGGSAsgtCDPDTGQCECKPNVTGRRCDRCAPGYYGDGP-PGC 46
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
384-408 |
1.40e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.87 E-value: 1.40e-03
10 20
....*....|....*....|....*
gi 25145020 384 GGRCLeCAHNTEGFNCERCKDGYYR 408
Cdd:pfam00053 17 TGQCL-CKPGVTGRHCDRCKPGYYG 40
|
|
| Laminin_EGF |
pfam00053 |
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six. |
1133-1178 |
1.76e-03 |
|
Laminin EGF domain; This family is like pfam00008 but has 8 conserved cysteines instead of six.
Pssm-ID: 395007 Cd Length: 49 Bit Score: 38.49 E-value: 1.76e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 25145020 1133 ECEPCPAPGQVCDPIDGSCVCPPNTVGEMCENCTTNAWDYHPLNGC 1178
Cdd:pfam00053 2 DCNPHGSLSDTCDPETGQCLCKPGVTGRHCDRCKPGYYGLPSDPPQ 47
|
|
| GumC |
COG3206 |
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis]; |
1833-2094 |
1.82e-03 |
|
Exopolysaccharide export protein/domain GumC/Wzc1 [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 442439 [Multi-domain] Cd Length: 687 Bit Score: 43.85 E-value: 1.82e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVErgEYVEKRLNRAQQEHKKAEELLKmvtaQKLnetifEDLKNRIDVLEQWMNDYREtiydvsKKDTADAE 1912
Cdd:COG3206 149 LAAAVANALAE--AYLEQNLELRREEARKALEFLE----EQL-----PELRKELEEAEAALEEFRQ------KNGLVDLS 211
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1913 RMSLVVgkrINRYKEVSNEIEKLRVEAEDQiaysrnsieKARSEELmnmfedKEKINMTLAELPDLVEqcqnitllySQL 1992
Cdd:COG3206 212 EEAKLL---LQQLSELESQLAEARAELAEA---------EARLAAL------RAQLGSGPDALPELLQ---------SPV 264
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1993 IDEYDEEYVQtagrhaekLEVQAQKIVDRFVDtrtetENP--LKASHAYENIVEALKNATEAVDSAAEASEAVSKmlgse 2070
Cdd:COG3206 265 IQQLRAQLAE--------LEAELAELSARYTP-----NHPdvIALRAQIAALRAQLQQEAQRILASLEAELEALQ----- 326
|
250 260
....*....|....*....|....
gi 25145020 2071 gsesgdANEESLRSQLEKLKNESS 2094
Cdd:COG3206 327 ------AREASLQAQLAQLEARLA 344
|
|
| EGF_Lam |
cd00055 |
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous ... |
383-410 |
1.91e-03 |
|
Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in tandem arrays; the domain contains 4 disulfide bonds (loops a-d) the first three resemble epidermal growth factor (EGF); the number of copies of this domain in the different forms of laminins is highly variable ranging from 3 up to 22 copies
Pssm-ID: 238012 Cd Length: 50 Bit Score: 38.49 E-value: 1.91e-03
10 20
....*....|....*....|....*...
gi 25145020 383 GGGRClECAHNTEGFNCERCKDGYYRPS 410
Cdd:cd00055 17 GTGQC-ECKPNTTGRRCDRCAPGYYGLP 43
|
|
| BAR |
smart00721 |
BAR domain; |
1848-2058 |
1.95e-03 |
|
BAR domain;
Pssm-ID: 214787 [Multi-domain] Cd Length: 239 Bit Score: 42.76 E-value: 1.95e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1848 VEKRLNRAQQehkKAEELLKMVTAQKLNEtIFEDLKNRIDVLEQWMND-YRETIYDVSKKDTADAE-----RMSLVVGKR 1921
Cdd:smart00721 2 FKKQFNRAKQ---KVGEKVGKAEKTKLDE-DFEELERRFDTTEAEIEKlQKDTKLYLQPNPAVRAKlasqkKLSKSLGEV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1922 INRYK-----EVSNEIEKLRV---EAEDQIAYSRNSIEKARSEELMNMfedkekINMTLAELPDLVEQcqnITLLYSQLI 1993
Cdd:smart00721 78 YEGGDdgeglGADSSYGKALDklgEALKKLLQVEESLSQVKRTFILPL------LNFLLGEFKEIKKA---RKKLERKLL 148
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 25145020 1994 DeYDeeYVQTAGRHAEKLEvqAQKIVDRFVDTRTETEnplKASHAYENIVEALKNATEA-VDSAAE 2058
Cdd:smart00721 149 D-YD--SARHKLKKAKKSK--EKKKDEKLAKAEEELR---KAKQEFEESNAQLVEELPQlVASRVD 206
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1880-2250 |
4.71e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.90 E-value: 4.71e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1880 EDLKNRIDVLEQWMNDYRETIYDVSKKDTADAErMSLVVGKRINRYKEVSNEIEKLrVEAEDQIAYSRNSIEKARSEELM 1959
Cdd:PTZ00440 532 EGLKNEIEGLIELIKYYLQSIETLIKDEKLKRS-MKNDIKNKIKYIEENVDHIKDI-ISLNDEIDNIIQQIEELINEALF 609
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1960 NM---------FEDKEKINMTLAELPDLVEQCQNITLLYSQLIDEYDEEY--------VQTAGRHAEKLEVQAQKIVDRF 2022
Cdd:PTZ00440 610 NKekfinekndLQEKVKYILNKFYKGDLQELLDELSHFLDDHKYLYHEAKskedlqtlLNTSKNEYEKLEFMKSDNIDNI 689
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2023 VDT-RTETENPLKAShayENIVEALKNA--TEAVDSAAEASEAVSKMLGSEGSESGDANE-ESLRSQLEKLKNE--SSLS 2096
Cdd:PTZ00440 690 IKNlKKELQNLLSLK---ENIIKKQLNNieQDISNSLNQYTIKYNDLKSSIEEYKEEEEKlEVYKHQIINRKNEfiLHLY 766
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2097 NVDN--SNAVKIVEELKKEKKDLTDRLGHLNELKTSIVKRLGVIKNEASSWDDKhdrmhsILKNGAKTAhERSANVKKES 2174
Cdd:PTZ00440 767 ENDKdlPDGKNTYEEFLQYKDTILNKENKISNDINILKENKKNNQDLLNSYNIL------IQKLEAHTE-KNDEELKQLL 839
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 25145020 2175 EGIKTEVSAIK-AEVEKLMNSTSSGVQEDMEKIRASRTGMEyGAQKLTKVNKLSTANQGRTDKMARNIAILKAKIEQ 2250
Cdd:PTZ00440 840 QKFPTEDENLNlKELEKEFNENNQIVDNIIKDIENMNKNIN-IIKTLNIAINRSNSNKQLVEHLLNNKIDLKNKLEQ 915
|
|
| PTZ00440 |
PTZ00440 |
reticulocyte binding protein 2-like protein; Provisional |
1847-2248 |
5.44e-03 |
|
reticulocyte binding protein 2-like protein; Provisional
Pssm-ID: 240419 [Multi-domain] Cd Length: 2722 Bit Score: 42.90 E-value: 5.44e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1847 YVEKRLNRAQQEHKKAE--ELLKMVTAQ--KLNETIFEDLKNRIDVLEQWMNDYRETIYDVSKKDTADAER-MSLVVGKR 1921
Cdd:PTZ00440 647 FLDDHKYLYHEAKSKEDlqTLLNTSKNEyeKLEFMKSDNIDNIIKNLKKELQNLLSLKENIIKKQLNNIEQdISNSLNQY 726
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1922 INRYKEVSNEIEKLRVEaEDQIAYSRNSIEKARSEELMNMFEDKEKinmtlaeLPDlveqCQNITllysqlideydEEYV 2001
Cdd:PTZ00440 727 TIKYNDLKSSIEEYKEE-EEKLEVYKHQIINRKNEFILHLYENDKD-------LPD----GKNTY-----------EEFL 783
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2002 QtagrHAEKLEVQAQKIVDRFVDTRTETENPLKASHAYENIVEALKNATEavdsaaEASEAVSKMLGSEGSEsgdaNEES 2081
Cdd:PTZ00440 784 Q----YKDTILNKENKISNDINILKENKKNNQDLLNSYNILIQKLEAHTE------KNDEELKQLLQKFPTE----DENL 849
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2082 LRSQLEKLKNE--SSLSNV--------DNSNAVKI--------------VEELKKEKKDLTDRLghlnELKTSIVKRLGV 2137
Cdd:PTZ00440 850 NLKELEKEFNEnnQIVDNIikdienmnKNINIIKTlniainrsnsnkqlVEHLLNNKIDLKNKL----EQHMKIINTDNI 925
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 2138 IkneasswdDKHDRMhsILKNgaktahersaNVKKESEGIKTEVSAI-----KAEVEKLMNStssgvqedMEKIRAS-RT 2211
Cdd:PTZ00440 926 I--------QKNEKL--NLLN----------NLNKEKEKIEKQLSDTkinnlKMQIEKTLEY--------YDKSKENiNG 977
|
410 420 430
....*....|....*....|....*....|....*..
gi 25145020 2212 GMEYGAQKLTKVNKLSTANQGRTDKMARNIAILKAKI 2248
Cdd:PTZ00440 978 NDGTHLEKLDKEKDEWEHFKSEIDKLNVNYNILNKKI 1014
|
|
| Smc |
COG1196 |
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ... |
1833-2150 |
9.23e-03 |
|
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 440809 [Multi-domain] Cd Length: 983 Bit Score: 41.85 E-value: 9.23e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1833 EAEAHLNATVERGEYVEKRLNRAQQEHKKAEELLkmvtaQKLNETIFEdLKNRIDVLEQWMNDYRETIydvskkdtADAE 1912
Cdd:COG1196 250 ELEAELEELEAELAELEAELEELRLELEELELEL-----EEAQAEEYE-LLAELARLEQDIARLEERR--------RELE 315
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1913 RmslvvgkRINRYKEVSNEIEKLRVEAEDQIAYSRNSIEKARSEELmnmfEDKEKINMTLAELPDLVEQcqnitllysql 1992
Cdd:COG1196 316 E-------RLEELEEELAELEEELEELEEELEELEEELEEAEEELE----EAEAELAEAEEALLEAEAE----------- 373
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 25145020 1993 IDEYDEEYVQTAGRHAEKLEVQAQKIVDRFVDTRTETENPLKASHAYENIVEALKNATEAVDSAAEASEAVSKMLGSEGS 2072
Cdd:COG1196 374 LAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAE 453
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 25145020 2073 EsgDANEESLRSQLEKLKNESSLSNVDNSNAVKIVEELKKEKKDLTDRLGhLNELKTSIVKRLGVIKNEASSWDDKHD 2150
Cdd:COG1196 454 L--EEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEA-DYEGFLEGVKAALLLAGLRGLAGAVAV 528
|
|
| |
