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Conserved domains on  [gi|17507197|ref|NP_492896|]
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MADF domain-containing protein [Caenorhabditis elegans]

Protein Classification

Myb/SANT-like transcription factor( domain architecture ID 10651957)

Myb/SANT-like transcription factor with an N-terminal MADF domain, which resembles the 3 alpha-helix bundle of the DNA-binding Myb domains

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
MADF smart00595
subfamily of SANT domain;
11-107 2.86e-18

subfamily of SANT domain;


:

Pssm-ID: 214738  Cd Length: 89  Bit Score: 77.78  E-value: 2.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507197     11 CLINAIRNRPVIWDKNYFGESNYRtLKTSCLREVTSELNsmfqmpikFTCEDVRSQWKNLKDTFVRKLRWVHEGKYMEDa 90
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKE-EKRKAWEEIAEELG--------LSVEECKKRWKNLRDRYRRELKRLQNGKSGGG- 70

                           90
                   ....*....|....*..
gi 17507197     91 mKEPTWKFYRMLTFLDE 107
Cdd:smart00595  71 -KKSKWEYFDRLSFLRP 86
 
Name Accession Description Interval E-value
MADF smart00595
subfamily of SANT domain;
11-107 2.86e-18

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 77.78  E-value: 2.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507197     11 CLINAIRNRPVIWDKNYFGESNYRtLKTSCLREVTSELNsmfqmpikFTCEDVRSQWKNLKDTFVRKLRWVHEGKYMEDa 90
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKE-EKRKAWEEIAEELG--------LSVEECKKRWKNLRDRYRRELKRLQNGKSGGG- 70

                           90
                   ....*....|....*..
gi 17507197     91 mKEPTWKFYRMLTFLDE 107
Cdd:smart00595  71 -KKSKWEYFDRLSFLRP 86
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 12-105 5.50e-16

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 71.55  E-value: 5.50e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507197    12 LINAIRNRPVIWDKNYfGESNYRTLKTSCLREVTSELNSmfqmpiKFTCEDVRSQWKNLKDTFVRKLRWVhegKYMEDAM 91
Cdd:pfam10545   1 LIELVREHPCLWDRSH-PDYRNRDARERAWEEIAEELGS------DVPVEDCKKRWKNLRDQYRRELRRK---RTNSGEL 70

                          90
                  ....*....|....
gi 17507197    92 KEPTWKFYRMLTFL 105
Cdd:pfam10545  71 YKSRWYYYEELSFL 84
 
Name Accession Description Interval E-value
MADF smart00595
subfamily of SANT domain;
11-107 2.86e-18

subfamily of SANT domain;


Pssm-ID: 214738  Cd Length: 89  Bit Score: 77.78  E-value: 2.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507197     11 CLINAIRNRPVIWDKNYFGESNYRtLKTSCLREVTSELNsmfqmpikFTCEDVRSQWKNLKDTFVRKLRWVHEGKYMEDa 90
Cdd:smart00595   1 RLIELVRERPCLWDRRHPDYRNKE-EKRKAWEEIAEELG--------LSVEECKKRWKNLRDRYRRELKRLQNGKSGGG- 70

                           90
                   ....*....|....*..
gi 17507197     91 mKEPTWKFYRMLTFLDE 107
Cdd:smart00595  71 -KKSKWEYFDRLSFLRP 86
MADF_DNA_bdg pfam10545
Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 ...
 12-105 5.50e-16

Alcohol dehydrogenase transcription factor Myb/SANT-like; The myb/SANT-like domain in Adf-1 (MADF) is an approximately 80-amino-acid module that directs sequence specific DNA binding to a site consisting of multiple tri-nucleotide repeats. The MADF domain is found in one or more copies in eukaryotic and viral proteins and is often associated with the BESS domain. It is likely that the MADF domain is more closely related to the myb/SANT domain than it is to other HTH domains.


Pssm-ID: 463144  Cd Length: 84  Bit Score: 71.55  E-value: 5.50e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507197    12 LINAIRNRPVIWDKNYfGESNYRTLKTSCLREVTSELNSmfqmpiKFTCEDVRSQWKNLKDTFVRKLRWVhegKYMEDAM 91
Cdd:pfam10545   1 LIELVREHPCLWDRSH-PDYRNRDARERAWEEIAEELGS------DVPVEDCKKRWKNLRDQYRRELRRK---RTNSGEL 70

                          90
                  ....*....|....
gi 17507197    92 KEPTWKFYRMLTFL 105
Cdd:pfam10545  71 YKSRWYYYEELSFL 84
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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