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Conserved domains on  [gi|17507063|ref|NP_492942|]
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AB hydrolase-1 domain-containing protein [Caenorhabditis elegans]

Protein Classification

alpha/beta fold hydrolase( domain architecture ID 1001822)

alpha/beta fold hydrolase catalyzes the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

CATH:  3.40.50.1820
Gene Ontology:  GO:0016787
PubMed:  12369917|15381402|1409539
SCOP:  3000102

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PRK10673 super family cl30399
esterase;
36-287 2.62e-28

esterase;


The actual alignment was detected with superfamily member PRK10673:

Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 109.43  E-value: 2.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   36 TPLILVPGLFGTKENWIQVGKDLSQRLGcmVFAVENRNHGSFSKAASMTYEEMADDLVGFIDWVrkitGEDKVNLHGHSM 115
Cdd:PRK10673  17 SPIVLVHGLFGSLDNLGVLARDLVNDHD--IIQVDMRNHGLSPRDPVMNYPAMAQDLLDTLDAL----QIEKATFIGHSM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  116 GGKAVTQL-ATTPEyssRIKSLIVEDMSPLGYPLKRA-EYLECIKQMIATDMnKSRS---EVMAE-LGEK-VSKVLLYQF 188
Cdd:PRK10673  91 GGKAVMALtALAPD---RIDKLVAIDIAPVDYHVRRHdEIFAAINAVSEAGA-TTRQqaaAIMRQhLNEEgVIQFLLKSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  189 VRGnlgedvngkaHWICNLNVIDETYIYLLSHDiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWSNHW 268
Cdd:PRK10673 167 VDG----------EWRFNVPVLWDQYPHIVGWE-KIPAWPHPALFIRGGNSPYVTEAYRDDLLAQFPQARAHVIAGAGHW 235

                        250
                 ....*....|....*....
gi 17507063  269 IHADDPKFFVDSICEFLEE 287
Cdd:PRK10673 236 VHAEKPDAVLRAIRRYLND 254
 
Name Accession Description Interval E-value
PRK10673 PRK10673
esterase;
36-287 2.62e-28

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 109.43  E-value: 2.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   36 TPLILVPGLFGTKENWIQVGKDLSQRLGcmVFAVENRNHGSFSKAASMTYEEMADDLVGFIDWVrkitGEDKVNLHGHSM 115
Cdd:PRK10673  17 SPIVLVHGLFGSLDNLGVLARDLVNDHD--IIQVDMRNHGLSPRDPVMNYPAMAQDLLDTLDAL----QIEKATFIGHSM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  116 GGKAVTQL-ATTPEyssRIKSLIVEDMSPLGYPLKRA-EYLECIKQMIATDMnKSRS---EVMAE-LGEK-VSKVLLYQF 188
Cdd:PRK10673  91 GGKAVMALtALAPD---RIDKLVAIDIAPVDYHVRRHdEIFAAINAVSEAGA-TTRQqaaAIMRQhLNEEgVIQFLLKSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  189 VRGnlgedvngkaHWICNLNVIDETYIYLLSHDiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWSNHW 268
Cdd:PRK10673 167 VDG----------EWRFNVPVLWDQYPHIVGWE-KIPAWPHPALFIRGGNSPYVTEAYRDDLLAQFPQARAHVIAGAGHW 235

                        250
                 ....*....|....*....
gi 17507063  269 IHADDPKFFVDSICEFLEE 287
Cdd:PRK10673 236 VHAEKPDAVLRAIRRYLND 254
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 35-287 8.52e-23

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 93.91  E-value: 8.52e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  35 GTPLILVPGLFGTKENWIQVGKDLSQRlgCMVFAVENRNHG-SFSKAASMTYEEMADDLVGFIDWVrkitGEDKVNLHGH 113
Cdd:COG0596  23 GPPVVLLHGLPGSSYEWRPLIPALAAG--YRVIAPDLRGHGrSDKPAGGYTLDDLADDLAALLDAL----GLERVVLVGH 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063 114 SMGGKAVTQLATtpEYSSRIKSLIVEDmsplgyplkraEYLECIKQMIATDMNKSRSevmaelgekvskvlLYQFVRGNL 193
Cdd:COG0596  97 SMGGMVALELAA--RHPERVAGLVLVD-----------EVLAALAEPLRRPGLAPEA--------------LAALLRALA 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063 194 GEDVNGkahwicnlnvidetyiyllshdiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWSNHWIHADD 273
Cdd:COG0596 150 RTDLRE-----------------------RLARITVPTLVIWGEKDPIVPPALARRLAELLPNAELVVLPGAGHFPPLEQ 206

                       250
                ....*....|....
gi 17507063 274 PKFFVDSICEFLEE 287
Cdd:COG0596 207 PEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 36-274 3.10e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 79.09  E-value: 3.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063    36 TPLILVPGLFGTKENWIQVGKDLsQRLGCMVFAVENRNHGsFSKAASMTYEEMADDLVGFIDWVRKITGEDKVNLHGHSM 115
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPAL-ARDGFRVIALDLRGFG-KSSRPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   116 GGKAVTQLAttPEYSSRIKSLIVedMSPLGYPLK----------------RAEYLECIKQMIATDMNK------SRSEVM 173
Cdd:pfam00561  79 GGLIALAYA--AKYPDRVKALVL--LGALDPPHEldeadrfilalfpgffDGFVADFAPNPLGRLVAKllalllLRLRLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   174 AELGEKVSKvLLYQFVRGNLGEDVNGKAHWicnlnvidETYIYLLSHDiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKM 253
Cdd:pfam00561 155 KALPLLNKR-FPSGDYALAKSLVTGALLFI--------ETWSTELRAK-FLGRLDEPTLIIWGDQDPLVPPQALEKLAQL 224

                         250       260
                  ....*....|....*....|.
gi 17507063   254 FPMVQFAETAWSNHWIHADDP 274
Cdd:pfam00561 225 FPNARLVVIPDAGHFAFLEGP 245
 
Name Accession Description Interval E-value
PRK10673 PRK10673
esterase;
36-287 2.62e-28

esterase;


Pssm-ID: 182637 [Multi-domain]  Cd Length: 255  Bit Score: 109.43  E-value: 2.62e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   36 TPLILVPGLFGTKENWIQVGKDLSQRLGcmVFAVENRNHGSFSKAASMTYEEMADDLVGFIDWVrkitGEDKVNLHGHSM 115
Cdd:PRK10673  17 SPIVLVHGLFGSLDNLGVLARDLVNDHD--IIQVDMRNHGLSPRDPVMNYPAMAQDLLDTLDAL----QIEKATFIGHSM 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  116 GGKAVTQL-ATTPEyssRIKSLIVEDMSPLGYPLKRA-EYLECIKQMIATDMnKSRS---EVMAE-LGEK-VSKVLLYQF 188
Cdd:PRK10673  91 GGKAVMALtALAPD---RIDKLVAIDIAPVDYHVRRHdEIFAAINAVSEAGA-TTRQqaaAIMRQhLNEEgVIQFLLKSF 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  189 VRGnlgedvngkaHWICNLNVIDETYIYLLSHDiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWSNHW 268
Cdd:PRK10673 167 VDG----------EWRFNVPVLWDQYPHIVGWE-KIPAWPHPALFIRGGNSPYVTEAYRDDLLAQFPQARAHVIAGAGHW 235

                        250
                 ....*....|....*....
gi 17507063  269 IHADDPKFFVDSICEFLEE 287
Cdd:PRK10673 236 VHAEKPDAVLRAIRRYLND 254
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 35-287 8.52e-23

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 93.91  E-value: 8.52e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  35 GTPLILVPGLFGTKENWIQVGKDLSQRlgCMVFAVENRNHG-SFSKAASMTYEEMADDLVGFIDWVrkitGEDKVNLHGH 113
Cdd:COG0596  23 GPPVVLLHGLPGSSYEWRPLIPALAAG--YRVIAPDLRGHGrSDKPAGGYTLDDLADDLAALLDAL----GLERVVLVGH 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063 114 SMGGKAVTQLATtpEYSSRIKSLIVEDmsplgyplkraEYLECIKQMIATDMNKSRSevmaelgekvskvlLYQFVRGNL 193
Cdd:COG0596  97 SMGGMVALELAA--RHPERVAGLVLVD-----------EVLAALAEPLRRPGLAPEA--------------LAALLRALA 149

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063 194 GEDVNGkahwicnlnvidetyiyllshdiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKMFPMVQFAETAWSNHWIHADD 273
Cdd:COG0596 150 RTDLRE-----------------------RLARITVPTLVIWGEKDPIVPPALARRLAELLPNAELVVLPGAGHFPPLEQ 206

                       250
                ....*....|....
gi 17507063 274 PKFFVDSICEFLEE 287
Cdd:COG0596 207 PEAFAAALRDFLAR 220
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 36-274 3.10e-17

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 79.09  E-value: 3.10e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063    36 TPLILVPGLFGTKENWIQVGKDLsQRLGCMVFAVENRNHGsFSKAASMTYEEMADDLVGFIDWVRKITGEDKVNLHGHSM 115
Cdd:pfam00561   1 PPVLLLHGLPGSSDLWRKLAPAL-ARDGFRVIALDLRGFG-KSSRPKAQDDYRTDDLAEDLEYILEALGLEKVNLVGHSM 78

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   116 GGKAVTQLAttPEYSSRIKSLIVedMSPLGYPLK----------------RAEYLECIKQMIATDMNK------SRSEVM 173
Cdd:pfam00561  79 GGLIALAYA--AKYPDRVKALVL--LGALDPPHEldeadrfilalfpgffDGFVADFAPNPLGRLVAKllalllLRLRLL 154

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   174 AELGEKVSKvLLYQFVRGNLGEDVNGKAHWicnlnvidETYIYLLSHDiRFGVFDGPTLFQRAPGSGFLPAAHKNRVEKM 253
Cdd:pfam00561 155 KALPLLNKR-FPSGDYALAKSLVTGALLFI--------ETWSTELRAK-FLGRLDEPTLIIWGDQDPLVPPQALEKLAQL 224

                         250       260
                  ....*....|....*....|.
gi 17507063   254 FPMVQFAETAWSNHWIHADDP 274
Cdd:pfam00561 225 FPNARLVVIPDAGHFAFLEGP 245
EstA COG1075
Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and ...
 36-137 9.43e-14

Triacylglycerol esterase/lipase EstA, alpha/beta hydrolase fold [Lipid transport and metabolism];


Pssm-ID: 440693 [Multi-domain]  Cd Length: 106  Bit Score: 66.01  E-value: 9.43e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  36 TPLILVPGLFGTKENWIQVGKDLsQRLGCMVFAVenrNHGSFSKaasmTYEEMADDLVGFIDWVRKITGEDKVNLHGHSM 115
Cdd:COG1075   6 YPVVLVHGLGGSAASWAPLAPRL-RAAGYPVYAL---NYPSTNG----SIEDSAEQLAAFVDAVLAATGAEKVDLVGHSM 77

                        90       100
                ....*....|....*....|..
gi 17507063 116 GGKAVTQLATTPEYSSRIKSLI 137
Cdd:COG1075  78 GGLVARYYLKRLGGAAKVARVV 99
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
35-137 8.67e-11

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 60.40  E-value: 8.67e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  35 GTPLILVPGLFGTKENWIQVGKDLSQRlGCMVFAVENRNHG--SFSKAASMTYEEMADDLVGFIDWVRKITGEdKVNLHG 112
Cdd:COG2267  28 RGTVVLVHGLGEHSGRYAELAEALAAA-GYAVLAFDLRGHGrsDGPRGHVDSFDDYVDDLRAALDALRARPGL-PVVLLG 105

                        90       100
                ....*....|....*....|....*
gi 17507063 113 HSMGGKAVTQLATtpEYSSRIKSLI 137
Cdd:COG2267 106 HSMGGLIALLYAA--RYPDRVAGLV 128
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
37-137 2.57e-08

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 53.48  E-value: 2.57e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  37 PLIL-VPGLFGTKEN-WIQVGKDLSQRlGCMVFAVENRNHGsfsKAASMTYEEMADDLVGFIDWVRK--ITGEDKVNLHG 112
Cdd:COG1506  24 PVVVyVHGGPGSRDDsFLPLAQALASR-GYAVLAPDYRGYG---ESAGDWGGDEVDDVLAAIDYLAArpYVDPDRIGIYG 99

                        90       100
                ....*....|....*....|....*
gi 17507063 113 HSMGGKAVTQLATtpEYSSRIKSLI 137
Cdd:COG1506 100 HSYGGYMALLAAA--RHPDRFKAAV 122
PRK14875 PRK14875
acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional
 35-136 3.94e-07

acetoin dehydrogenase E2 subunit dihydrolipoyllysine-residue acetyltransferase; Provisional


Pssm-ID: 184875 [Multi-domain]  Cd Length: 371  Bit Score: 50.71  E-value: 3.94e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063   35 GTPLILVPGLFGTKENWIQVGKDLSqrLGCMVFAVENRNHGSFSKA-ASMTYEEMADDLVGFIDwvrkITGEDKVNLHGH 113
Cdd:PRK14875 131 GTPVVLIHGFGGDLNNWLFNHAALA--AGRPVIALDLPGHGASSKAvGAGSLDELAAAVLAFLD----ALGIERAHLVGH 204

                         90       100
                 ....*....|....*....|...
gi 17507063  114 SMGGKAVTQLATtpEYSSRIKSL 136
Cdd:PRK14875 205 SMGGAVALRLAA--RAPQRVASL 225
PhaC COG3243
Poly-beta-hydroxybutyrate synthase [Lipid transport and metabolism];
96-137 4.64e-06

Poly-beta-hydroxybutyrate synthase [Lipid transport and metabolism];


Pssm-ID: 442475 [Multi-domain]  Cd Length: 545  Bit Score: 47.64  E-value: 4.64e-06
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 17507063  96 IDWVRKITGEDKVNLHGHSMGGkavTQLATT--------PEyssRIKSLI 137
Cdd:COG3243 267 VDAVREITGEDKVNLLGYCLGG---TLLAIYaallaargPD---RVASLT 310
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 38-137 5.02e-06

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 46.82  E-value: 5.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063    38 LILVPGLFGTKENWIQVGKDLSQRlGCMVFAVENRNHGsFSKAASM---TYEEMADDLVGFIDWVRKITGEDKVNLHGHS 114
Cdd:pfam12146   7 VVLVHGLGEHSGRYAHLADALAAQ-GFAVYAYDHRGHG-RSDGKRGhvpSFDDYVDDLDTFVDKIREEHPGLPLFLLGHS 84

                          90       100
                  ....*....|....*....|...
gi 17507063   115 MGGKAVTQLATtpEYSSRIKSLI 137
Cdd:pfam12146  85 MGGLIAALYAL--RYPDKVDGLI 105
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 38-155 5.32e-06

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 46.31  E-value: 5.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063    38 LILVPGLFGTKENWIQVGKDlsqrlGCMVFAVENRNHGSFSKAASmTYEEMADdlvgFIDWVRKITGEDKVNLHGHSMGG 117
Cdd:pfam12697   1 VVLVHGAGLSAAPLAALLAA-----GVAVLAPDLPGHGSSSPPPL-DLADLAD----LAALLDELGAARPVVLVGHSLGG 70

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 17507063   118 KAVTQLATtpeYSSRIKSLIVEDMSPLGYPLKRAEYLE 155
Cdd:pfam12697  71 AVALAAAA---AALVVGVLVAPLAAPPGLLAALLALLA 105
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 33-141 1.92e-03

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 39.13  E-value: 1.92e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  33 SKGTPLILV-PGLFGTKENWIQVGKDLSQRlGCMVFAVENRNHGsfskaASM-TYEEMAD----DLVGFIDWVRKITG-- 104
Cdd:COG1073  34 SKKYPAVVVaHGNGGVKEQRALYAQRLAEL-GFNVLAFDYRGYG-----ESEgEPREEGSperrDARAAVDYLRTLPGvd 107

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 17507063 105 EDKVNLHGHSMGGKAVTQLATTPEyssRIKSLIVEDM 141
Cdd:COG1073 108 PERIGLLGISLGGGYALNAAATDP---RVKAVILDSP 141
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
39-143 6.40e-03

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 37.23  E-value: 6.40e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  39 ILVPGLFGTKENWIQVGKDLSQRlGCMVFAVENRNHGSfskaasmTYEEMADdlVGFIDWVRKIT--------GEDKVNL 110
Cdd:COG1647  19 LLLHGFTGSPAEMRPLAEALAKA-GYTVYAPRLPGHGT-------SPEDLLK--TTWEDWLEDVEeayeilkaGYDKVIV 88

                        90       100       110
                ....*....|....*....|....*....|...
gi 17507063 111 HGHSMGGKAVTQLAttpEYSSRIKSLIVedMSP 143
Cdd:COG1647  89 IGLSMGGLLALLLA---ARYPDVAGLVL--LSP 116
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
38-126 8.84e-03

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 36.87  E-value: 8.84e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17507063  38 LILVPGLFGTKENWIQVGKDLsQRLGCMVFAVE-------NRNHGSFSKAAS-MTYEEMADDLVGFIDWVRKITGED--K 107
Cdd:COG0412  32 VVVLHEIFGLNPHIRDVARRL-AAAGYVVLAPDlygrggpGDDPDEARALMGaLDPELLAADLRAALDWLKAQPEVDagR 110

                        90
                ....*....|....*....
gi 17507063 108 VNLHGHSMGGKAVTQLATT 126
Cdd:COG0412 111 VGVVGFCFGGGLALLAAAR 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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