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Conserved domains on  [gi|17536781|ref|NP_493767|]
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DDE_3 domain-containing protein [Caenorhabditis elegans]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
COG3335 super family cl41994
Transposase [Mobilome: prophages, transposons];
3-52 3.65e-08

Transposase [Mobilome: prophages, transposons];


The actual alignment was detected with superfamily member COG3335:

Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 49.09  E-value: 3.65e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 17536781   3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSKlETVRTQAIQFLKSI 52
Cdd:COG3335 226 ELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSK-DELKAAVRSFLDRI 274
 
Name Accession Description Interval E-value
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
3-52 3.65e-08

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 49.09  E-value: 3.65e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 17536781   3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSKlETVRTQAIQFLKSI 52
Cdd:COG3335 226 ELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSK-DELKAAVRSFLDRI 274
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
 3-37 1.15e-05

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 41.12  E-value: 1.15e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 17536781     3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSK 37
Cdd:pfam13358 108 ELHYLPPYSPELNPIEILWSVLKRELLNNRRFKDL 142
transpos_IS630 NF033545
IS630 family transposase;
3-51 2.69e-04

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 38.01  E-value: 2.69e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 17536781    3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSKlETVRTQAIQFLKS 51
Cdd:NF033545 251 ELHYLPPYSPWLNPIERVWAVLKRRLLRNRAFRSV-DELREAIDAFLNR 298
 
Name Accession Description Interval E-value
COG3335 COG3335
Transposase [Mobilome: prophages, transposons];
3-52 3.65e-08

Transposase [Mobilome: prophages, transposons];


Pssm-ID: 442564 [Multi-domain]  Cd Length: 292  Bit Score: 49.09  E-value: 3.65e-08
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 17536781   3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSKlETVRTQAIQFLKSI 52
Cdd:COG3335 226 ELLFLPPYSPDLNPIERLWSKLKALLRKNRAFRSK-DELKAAVRSFLDRI 274
DDE_3 pfam13358
DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are ...
 3-37 1.15e-05

DDE superfamily endonuclease; This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.


Pssm-ID: 433142 [Multi-domain]  Cd Length: 146  Bit Score: 41.12  E-value: 1.15e-05
                          10        20        30
                  ....*....|....*....|....*....|....*
gi 17536781     3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSK 37
Cdd:pfam13358 108 ELHYLPPYSPELNPIEILWSVLKRELLNNRRFKDL 142
transpos_IS630 NF033545
IS630 family transposase;
3-51 2.69e-04

IS630 family transposase;


Pssm-ID: 468076 [Multi-domain]  Cd Length: 298  Bit Score: 38.01  E-value: 2.69e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 17536781    3 KIVRLPPYHCCLNPIELIWNQLKSFLRKHGKLDSKlETVRTQAIQFLKS 51
Cdd:NF033545 251 ELHYLPPYSPWLNPIERVWAVLKRRLLRNRAFRSV-DELREAIDAFLNR 298
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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