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Conserved domains on  [gi|1799133619|ref|NP_494461|]
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Serpentine Receptor, class I [Caenorhabditis elegans]

Protein Classification

class I serpentine receptor( domain architecture ID 10563430)

class I serpentine receptor (Sri) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Gene Ontology:  GO:0016020
TCDB:  9.A.14

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
1-303 3.81e-112

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 313539  Cd Length: 303  Bit Score: 327.58  E-value: 3.81e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619   1 MSIAFSPSFWLIAYYYSIGFISLIFNVITILLIVFKSYKLDSFKYYLLAYQVSCANYVLQLTILFQPMPLFPLLGGYCQG 80
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  81 FLATYLGIWAHYMITINIASAVIEVELLTICFIMKQQSLSLIINKHVIPESLLYTGAGAFIYIPLSVFLTFRQITMSQED 160
Cdd:pfam10327  81 FLATVFGISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619 161 QMAYIATNHPEYHRNFEELQNFAIFHFNSWCYYLVVVTISGGLFCGGAAIFTTADMFRMMKDLQTRVSRSSLKRYRATIQ 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSLPNFAIYDYNPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAALR 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1799133619 241 SLIAQLVVSMMLVVPLTTFVALIFNKSEYAQAIAQFCLAICALHSIVNAGVLILSTSQYRNFL 303
Cdd:pfam10327 241 SLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
 
Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
1-303 3.81e-112

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 327.58  E-value: 3.81e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619   1 MSIAFSPSFWLIAYYYSIGFISLIFNVITILLIVFKSYKLDSFKYYLLAYQVSCANYVLQLTILFQPMPLFPLLGGYCQG 80
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  81 FLATYLGIWAHYMITINIASAVIEVELLTICFIMKQQSLSLIINKHVIPESLLYTGAGAFIYIPLSVFLTFRQITMSQED 160
Cdd:pfam10327  81 FLATVFGISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619 161 QMAYIATNHPEYHRNFEELQNFAIFHFNSWCYYLVVVTISGGLFCGGAAIFTTADMFRMMKDLQTRVSRSSLKRYRATIQ 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSLPNFAIYDYNPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAALR 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1799133619 241 SLIAQLVVSMMLVVPLTTFVALIFNKSEYAQAIAQFCLAICALHSIVNAGVLILSTSQYRNFL 303
Cdd:pfam10327 241 SLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
 
Name Accession Description Interval E-value
7TM_GPCR_Sri pfam10327
Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis ...
1-303 3.81e-112

Serpentine type 7TM GPCR chemoreceptor Sri; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Sri is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 313539  Cd Length: 303  Bit Score: 327.58  E-value: 3.81e-112
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619   1 MSIAFSPSFWLIAYYYSIGFISLIFNVITILLIVFKSYKLDSFKYYLLAYQVSCANYVLQLTILFQPMPLFPLLGGYCQG 80
Cdd:pfam10327   1 MNIDFTVPFWLILYYHIIGTISLILNLLGIYLIIFKSGKIDNFRYYLLYFQISCTLTDIHLTFLMQPIPLFPIIAGYCNG 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  81 FLATYLGIWAHYMITINIASAVIEVELLTICFIMKQQSLSLIINKHVIPESLLYTGAGAFIYIPLSVFLTFRQITMSQED 160
Cdd:pfam10327  81 FLATVFGISSHYLMTIFVFLLSFQLESLLLCFVRKHQAIAKILSKHVIPKWLYIFLYILCHIFPFLTAFLFYQSGLSREE 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619 161 QMAYIATNHPEYHRNFEELQNFAIFHFNSWCYYLVVVTISGGLFCGGAAIFTTADMFRMMKDLQTRVSRSSLKRYRATIQ 240
Cdd:pfam10327 161 QLEYVKENYPEYLSQFSSLPNFAIYDYNPWLIVFGILAIFGGSLSFLILVYLTVDMFRMLKRLRKKISAQTYQKHRAALR 240
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 1799133619 241 SLIAQLVVSMMLVVPLTTFVALIFNKSEYAQAIAQFCLAICALHSIVNAGVLILSTSQYRNFL 303
Cdd:pfam10327 241 SLIAQFATSPVCILPPFAFVVVVLFPIEYSQEISEILLAIFSTHSSVNSIVLILTTPPYRKFL 303
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
6-308 9.36e-14

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 70.65  E-value: 9.36e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619   6 SPSFWLIAYYySIGFISLIFNVITILLIVFKS-YKLDSFKYYLLAYQVSCANYVLQLTILFQPMPLFPLLGGYCQGFLaT 84
Cdd:pfam10318   2 SPDFLSTSLH-IITVISIPIHIFGFYCILFKTpKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLL-S 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  85 YLGIWAHYMITINIASavIEVELLTICFIMKQQSLSLIINKHVIPESLLYTGAGAFIYIPLSVFLTFRQITM-SQEDQMA 163
Cdd:pfam10318  80 YLGVPTPIQFYIGVTS--LALVGVSIILLFENRYSILFTNKKRITWKKTRVLYLIFNYIIALLFLIPIYLNIpDQEAAKL 157
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619 164 YIATNHPEYHRNFEELQNFAIFHFNSWcYYLVVVTISGGLFCGGAAIFTTADMFRMMKDLQTRVSRSSLKRYRATIQSLI 243
Cdd:pfam10318 158 KVLKKLPCLPPEFFDNPPVFVLAIDST-YFLICIVLLILILIIQILFFVFLTIYYLFKSVKSSLSKKTRKLQKKFFIALI 236
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1799133619 244 AQLVVSMMLVVPLTTFVALIFNKSEYAQAIAQFCLAICALHSIVNAGVLILSTSQYRNFLARKLP 308
Cdd:pfam10318 237 IQVSIPLIVILIPLIYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
14-262 2.62e-04

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 42.15  E-value: 2.62e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  14 YYYSIGFISLIFNVITILLIVFKSYK-LDSFKYYLLAYQV-----SCANYVLQLTILFQPMPLFPLLGGYCQgflatYLG 87
Cdd:pfam10317   4 YYPIFFILGLILNLLLLYLIIFKSPKsLKTYRILLLNTAItqiisCILAFFTQQRIIPNGVSMALISYGPCK-----YFG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619  88 IWAHYMI-TINIASAVIEVELLTICFIMKQQSLsliinKHVIPESLLYTGAGAFIYIPLSVFLTFRQITMSQEDQM-AYI 165
Cdd:pfam10317  79 PWFCYSGySLLQHFLLHSGWSLLLTFYYRYYIL-----KHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVeALT 153
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1799133619 166 ATNHPEYhrNFEELQNFAIFHFNSWCYYLVVVTISGGLFCGGAAIFTTADM-FRMMKDLQTRVSRSSLKRYRATIQSLIA 244
Cdd:pfam10317 154 KELHPNY--NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKiLKLLNSNSVNMSPTTKAQHRQLIKGLTI 231
                         250
                  ....*....|....*...
gi 1799133619 245 QLVVSMMLVVPLTTFVAL 262
Cdd:pfam10317 232 QALLPLFSYIPGVTLYLL 249
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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