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Conserved domains on  [gi|17533747|ref|NP_496054|]
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Glycosyltransferase family 92 protein [Caenorhabditis elegans]

Protein Classification

core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein( domain architecture ID 706199)

core-2/I-branching beta-1,6-N-acetylglucosaminyltransferase family protein similar to Homo sapiens xylosyltransferase 1 and Arabidopsis thaliana beta-glucuronosyltransferase GlcAT14A/B/C

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Branch super family cl27418
Core-2/I-Branching enzyme; This is a family of two different beta-1, ...
 105-202 8.73e-13

Core-2/I-Branching enzyme; This is a family of two different beta-1,6-N-acetylglucosaminyltransferase enzymes, I-branching enzyme and core-2 branching enzyme. I-branching enzyme is responsible for the production of the blood group I-antigen during embryonic development. Core-2 branching enzyme forms crucial side-chain branches in O-glycans. This is a fmmily of glycosyl-transferases that are Type II membrane proteins that are found in the endoplasmic reticulum (ER) and Golgi apparatus.


The actual alignment was detected with superfamily member pfam02485:

Pssm-ID: 452742  Cd Length: 250  Bit Score: 67.31  E-value: 8.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533747   105 FIRVVSK-DYDFVEEVLAMMHSPIHFFCFVLDINSEPLFKERMFRLGDCMVNVLV-PRELFNTSTAHGTLNAHRRCLREI 182
Cdd:pfam02485   3 FMFLTYKgDLPLLELWLRFFYHPENLYSIYVDSKAPSYFRERVRALASCFFNVRViPKSESVDWGGPSMVAAELRLLANL 82

                          90       100
                  ....*....|....*....|..
gi 17533747   183 --DEFDWKHAVITAEHDIPLHS 202
Cdd:pfam02485  83 llLDPSWDYFILLSESDIPLKT 104
 
Name Accession Description Interval E-value
Branch pfam02485
Core-2/I-Branching enzyme; This is a family of two different beta-1, ...
 105-202 8.73e-13

Core-2/I-Branching enzyme; This is a family of two different beta-1,6-N-acetylglucosaminyltransferase enzymes, I-branching enzyme and core-2 branching enzyme. I-branching enzyme is responsible for the production of the blood group I-antigen during embryonic development. Core-2 branching enzyme forms crucial side-chain branches in O-glycans. This is a fmmily of glycosyl-transferases that are Type II membrane proteins that are found in the endoplasmic reticulum (ER) and Golgi apparatus.


Pssm-ID: 426795  Cd Length: 250  Bit Score: 67.31  E-value: 8.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533747   105 FIRVVSK-DYDFVEEVLAMMHSPIHFFCFVLDINSEPLFKERMFRLGDCMVNVLV-PRELFNTSTAHGTLNAHRRCLREI 182
Cdd:pfam02485   3 FMFLTYKgDLPLLELWLRFFYHPENLYSIYVDSKAPSYFRERVRALASCFFNVRViPKSESVDWGGPSMVAAELRLLANL 82

                          90       100
                  ....*....|....*....|..
gi 17533747   183 --DEFDWKHAVITAEHDIPLHS 202
Cdd:pfam02485  83 llLDPSWDYFILLSESDIPLKT 104
 
Name Accession Description Interval E-value
Branch pfam02485
Core-2/I-Branching enzyme; This is a family of two different beta-1, ...
 105-202 8.73e-13

Core-2/I-Branching enzyme; This is a family of two different beta-1,6-N-acetylglucosaminyltransferase enzymes, I-branching enzyme and core-2 branching enzyme. I-branching enzyme is responsible for the production of the blood group I-antigen during embryonic development. Core-2 branching enzyme forms crucial side-chain branches in O-glycans. This is a fmmily of glycosyl-transferases that are Type II membrane proteins that are found in the endoplasmic reticulum (ER) and Golgi apparatus.


Pssm-ID: 426795  Cd Length: 250  Bit Score: 67.31  E-value: 8.73e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17533747   105 FIRVVSK-DYDFVEEVLAMMHSPIHFFCFVLDINSEPLFKERMFRLGDCMVNVLV-PRELFNTSTAHGTLNAHRRCLREI 182
Cdd:pfam02485   3 FMFLTYKgDLPLLELWLRFFYHPENLYSIYVDSKAPSYFRERVRALASCFFNVRViPKSESVDWGGPSMVAAELRLLANL 82

                          90       100
                  ....*....|....*....|..
gi 17533747   183 --DEFDWKHAVITAEHDIPLHS 202
Cdd:pfam02485  83 llLDPSWDYFILLSESDIPLKT 104
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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