|
Name |
Accession |
Description |
Interval |
E-value |
| PRK09259 |
PRK09259 |
putative oxalyl-CoA decarboxylase; Validated |
68-615 |
4.00e-171 |
|
putative oxalyl-CoA decarboxylase; Validated
Pssm-ID: 236433 [Multi-domain] Cd Length: 569 Bit Score: 499.51 E-value: 4.00e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 68 DGSNMDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGIL 147
Cdd:PRK09259 6 QLQLTDGFHLVIDALKLNGIDTIYGVVGIPITDLARLAQAEGIRYIGFRHEQSAGNAAAAAGFLTQKPGVCLTVSAPGFL 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGGTAD---VDLEnRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAV 224
Cdd:PRK09259 86 NGLTALANATTNCFPMIMISGSSEreiVDLQ-QGDYEELDQLNAAKPFCKAAFRVNRAEDIGIGVARAIRTAVSGRPGGV 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 225 YVDLPGNLVLTSTEEEISFPPQVPL--PAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSeRGATQVQQFLTKSKLP 302
Cdd:PRK09259 165 YLDLPAKVLAQTMDADEALTSLVKVvdPAPAQLPAPEAVDRALDLLKKAKRPLIILGKGAAYA-QADEQIREFVEKTGIP 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 303 WLATPGGKGVASDLHPRFIGQARSLALREADTVFLIGARFNWILHFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLG 382
Cdd:PRK09259 244 FLPMSMAKGLLPDTHPQSAAAARSLALANADVVLLVGARLNWLLSHGKGKTWGADKKFIQIDIEPQEIDSNRPIAAPVVG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 383 DIGETLAELTPRLGDWTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANN-DVIVINEGANTMD 461
Cdd:PRK09259 324 DIGSVMQALLAGLKQNTFKAPAEWLDALAERKEKNAAKMAEKLSTDTQPMNFYNALGAIRDVLKENpDIYLVNEGANTLD 403
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 462 IGRTMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALwardhSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNS 541
Cdd:PRK09259 404 LARNIIDMYKPRHRLDCGTWGVMGIGMGYAIAAAV-----ETGKPVVAIEGDSAFGFSGMEVETICRYNLPVTVVIFNNG 478
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17531301 542 GIYRGllpeDDKAIEGDRTLALPVLSLTAecRYEEMCKAFGGAGTVVRTVPEIKAALEKAFqKTDGPTVINALI 615
Cdd:PRK09259 479 GIYRG----DDVNLSGAGDPSPTVLVHHA--RYDKMMEAFGGVGYNVTTPDELRHALTEAI-ASGKPTLINVVI 545
|
|
| IlvB |
COG0028 |
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino ... |
72-618 |
3.03e-124 |
|
Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme [Amino acid transport and metabolism, Coenzyme transport and metabolism]; Acetolactate synthase large subunit or other thiamine pyrophosphate-requiring enzyme is part of the Pathway/BioSystem: Isoleucine, leucine, valine biosynthesis
Pssm-ID: 439799 [Multi-domain] Cd Length: 548 Bit Score: 378.35 E-value: 3.03e-124
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVG---FPVIEvGMAAQAhGIKYIGCRNEQAAAYaaqaM--GY--LTGKPVALLVVSGP 144
Cdd:COG0028 3 MTGADALVEALEAEGVETVFGVPGgaiLPLYD-ALRRQS-GIRHILVRHEQGAAF----MadGYarATGKPGVCLVTSGP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 145 GILHAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAV 224
Cdd:COG0028 77 GATNLVTGLADAYMDSVPVLAITGQVPTSLIGRGAFQEVDQVGLFRPITKWSYLVTDPEDLPEVLRRAFRIATSGRPGPV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 225 YVDLPGNlVLTSTEEEISFPPQVPLPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAaWSERGATQVQQFLTKSKLPWL 304
Cdd:COG0028 157 VLDIPKD-VQAAEAEEEPAPPELRGYRPRPAPDPEAIEEAAELLAAAKRPVILAGGGA-RRAGAAEELRALAERLGAPVV 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 305 ATPGGKGVASDLHPRFIG-------QARSLALREADTVFLIGARFNWILHFGLPPrFQKDVKVVQIDICPEEFHQNVKTE 377
Cdd:COG0028 235 TTLMGKGAFPEDHPLYLGmlgmhgtPAANEALAEADLVLAVGARFDDRVTGNWDE-FAPDAKIIHIDIDPAEIGKNYPVD 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 378 VPLLGDIGETLAELTPRLGDwTYDESTEWFKKLRENAEKNRAAVekfvDDHSTPLNYYAAYQPIREFLANNDVIVINEGA 457
Cdd:COG0028 314 LPIVGDAKAVLAALLEALEP-RADDRAAWLARIAAWRAEYLAAY----AADDGPIKPQRVIAALREALPDDAIVVTDVGQ 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 458 NTMDIGRtMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALwARdhsPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVI 537
Cdd:COG0028 389 HQMWAAR-YLRFRRPRRFLTSGGLGTMGYGLPAAIGAKL-AR---PDRPVVAITGDGGFQMNLQELATAVRYGLPVKVVV 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 538 INNSGiYrGLLPEDDKAIEGDRtlalPVLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVINALIST 617
Cdd:COG0028 464 LNNGG-L-GMVRQWQELFYGGR----YSGTDLPNPDFAKLAEAFGAKGERVETPEELEAALEEALA-SDGPALIDVRVDP 536
|
.
gi 17531301 618 D 618
Cdd:COG0028 537 E 537
|
|
| TPP_BZL_OCoD_HPCL |
cd02004 |
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of ... |
434-616 |
2.31e-76 |
|
Thiamine pyrophosphate (TPP) family, BZL_OCoD_HPCL subfamily, TPP-binding module; composed of proteins similar to benzaldehyde lyase (BZL), oxalyl-CoA decarboxylase (OCoD) and 2-hydroxyphytanoyl-CoA lyase (2-HPCL). Pseudomonas fluorescens biovar I BZL cleaves the acyloin linkage of benzoin producing 2 molecules of benzaldehyde and enabling the Pseudomonas to grow on benzoin as the sole carbon and energy source. OCoD has a role in the detoxification of oxalate, catalyzing the decarboxylation of oxalyl-CoA to formate. 2-HPCL is a peroxisomal enzyme which plays a role in the alpha-oxidation of 3-methyl-branched fatty acids, catalyzing the cleavage of 2-hydroxy-3-methylacyl-CoA into formyl-CoA and a 2-methyl-branched fatty aldehyde. All these enzymes depend on Mg2+ and TPP for activity.
Pssm-ID: 238962 [Multi-domain] Cd Length: 172 Bit Score: 240.90 E-value: 2.31e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 434 YYAAYQPIREFLANnDVIVINEGANTMDIGRTMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALWARDHspktKVLVVQGD 513
Cdd:cd02004 1 PYRVLHELQEALPD-DAIIVSDGGNTMDWARYILRPRKPRHRLDAGTFGTLGVGLGYAIAAALARPDK----RVVLVEGD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 514 SAFGFSAMELETIARYNLPVVTVIINNSGIYRGLLPEDDKAiegdrTLALPVLSLTAECRYEEMCKAFGGAGTVVRTVPE 593
Cdd:cd02004 76 GAFGFSGMELETAVRYNLPIVVVVGNNGGWYQGLDGQQLSY-----GLGLPVTTLLPDTRYDLVAEAFGGKGELVTTPEE 150
|
170 180
....*....|....*....|...
gi 17531301 594 IKAALEKAFQKtDGPTVINALIS 616
Cdd:cd02004 151 LKPALKRALAS-GKPALINVIID 172
|
|
| acolac_lg |
TIGR00118 |
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form ... |
72-623 |
8.32e-70 |
|
acetolactate synthase, large subunit, biosynthetic type; Two groups of proteins form acetolactate from two molecules of pyruvate. The type of acetolactate synthase described in this model also catalyzes the formation of acetohydroxybutyrate from pyruvate and 2-oxobutyrate, an early step in the branched chain amino acid biosynthesis; it is therefore also termed acetohydroxyacid synthase. In bacteria, this catalytic chain is associated with a smaller regulatory chain in an alpha2/beta2 heterotetramer. Acetolactate synthase is a thiamine pyrophosphate enzyme. In this type, FAD and Mg++ are also found. Several isozymes of this enzyme are found in E. coli K12, one of which contains a frameshift in the large subunit gene and is not expressed. [Amino acid biosynthesis, Pyruvate family]
Pssm-ID: 272915 [Multi-domain] Cd Length: 558 Bit Score: 236.54 E-value: 8.32e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEV-GMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:TIGR00118 1 MSGAEAIIESLKDEGVKTVFGYPGGAILPIyDALYNDSGIEHILVRHEQGAAHAADGYARASGKVGVVLVTSGPGATNLV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:TIGR00118 81 TGIATAYMDSIPMVVFTGQVPTSLIGSDAFQEADILGITMPITKHSFQVKSAEDIPRIIKEAFHIATTGRPGPVLVDLPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NlvLTSTEEEISFPPQVPLP--APVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPG 308
Cdd:TIGR00118 161 D--VTTAEIEYPYPEKVNLPgyRPTVKGHPLQIKKAAELINLAKKPVILVGGGVIIAG-ASEELKELAERIQIPVTTTLM 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQA-------RSLALREADTVFLIGARF-----NWILHFGlpPRfqkdVKVVQIDICPEEFHQNVKT 376
Cdd:TIGR00118 238 GLGSFPEDHPLSLGMLgmhgtktANLAVHECDLIIAVGARFddrvtGNLAKFA--PN----AKIIHIDIDPAEIGKNVRV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 377 EVPLLGDIGETLAELTPRLGDWTYDESTEWFKKLrenaEKNRAAVEKFVDDHSTPLNYYAAYQPIREFlANNDVIVineg 456
Cdd:TIGR00118 312 DIPIVGDARNVLEELLKKLFELKERKESAWLEQI----NKWKKEYPLKMDYTEEGIKPQQVIEELSRV-TKDEAIV---- 382
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 457 anTMDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYN 530
Cdd:TIGR00118 383 --TTDVGQHQMwaaqfyPFRKPRRFITSGGLGTM----GFGLPAAIGAKVAKPESTVICITGDGSFQMNLQELSTAVQYD 456
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 531 LPVVTVIINNSgiYRGLLPEDDKAIEGDRTLALPVLSLTAecrYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTV 610
Cdd:TIGR00118 457 IPVKILILNNR--YLGMVRQWQELFYEERYSHTHMGSLPD---FVKLAEAYGIKGIRIEKPEELDEKLKEALS-SNEPVL 530
|
570
....*....|...
gi 17531301 611 INALISTDSERKP 623
Cdd:TIGR00118 531 LDVVVDKPENVLP 543
|
|
| PRK05858 |
PRK05858 |
acetolactate synthase; |
70-620 |
5.33e-69 |
|
acetolactate synthase;
Pssm-ID: 235629 [Multi-domain] Cd Length: 542 Bit Score: 233.84 E-value: 5.33e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 70 SNMDGASITAAALKSQGVEYMFGVVG---FPVIEvgmAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGI 146
Cdd:PRK05858 3 QTGHAGRLAARRLKAHGVDTMFTLSGghlFPLYD---GAREEGIRLIDVRHEQTAAFAAEAWAKLTRVPGVAVLTAGPGV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 147 LHAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYV 226
Cdd:PRK05858 80 TNGMSAMAAAQFNQSPLVVLGGRAPALRWGMGSLQEIDHVPFVAPVTKFAATAQSAENAGRLVDQALQAAVTPHRGPVFV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 227 DLPGNLVLTSTEEEISFPPQVPLPAPVSIPPiAEIEKAIDTLKSAKKPLVIVGKGaAWSERGATQVQQFLTKSKLPWLAT 306
Cdd:PRK05858 160 DFPMDHAFSMADDDGRPGALTELPAGPTPDP-DALARAAGLLAEAQRPVIMAGTD-VWWGHAEAALLRLAEELGIPVLMN 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 307 PGGKGVASDLHPRFIGQARSLALREADTVFLIGARFNWILHFGLpprFQKDVKVVQIDICPEEFHQNVKTEVPLLGDIGE 386
Cdd:PRK05858 238 GMGRGVVPADHPLAFSRARGKALGEADVVLVVGVPMDFRLGFGV---FGGTAQLVHVDDAPPQRAHHRPVAAGLYGDLSA 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 387 TLAELTPRLGDWTydESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVIVINEGANTMDIGRtM 466
Cdd:PRK05858 315 ILSALAGAGGDRT--DHQGWIEELRTAETAARARDAAELADDRDPIHPMRVYGELAPLLDRDAIVIGDGGDFVSYAGR-Y 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 467 MPSRLPKRRLDAGTFGTMGVGHGFSLAAALwARdhsPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNsGIYrG 546
Cdd:PRK05858 392 IDPYRPGCWLDPGPFGCLGTGPGYALAARL-AR---PSRQVVLLQGDGAFGFSLMDVDTLVRHNLPVVSVIGNN-GIW-G 465
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17531301 547 LLPEDDKAIEGDRTLAlpvlSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVINALisTDSE 620
Cdd:PRK05858 466 LEKHPMEALYGYDVAA----DLRPGTRYDEVVRALGGHGELVTVPAELGPALERAFA-SGVPYLVNVL--TDPS 532
|
|
| PRK08527 |
PRK08527 |
acetolactate synthase large subunit; |
72-615 |
2.21e-57 |
|
acetolactate synthase large subunit;
Pssm-ID: 181458 [Multi-domain] Cd Length: 563 Bit Score: 203.02 E-value: 2.21e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEV--GMAAQAHgIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHA 149
Cdd:PRK08527 3 LSGSQMVCEALKEEGVKVVFGYPGGAILNIydEIYKQNY-FKHILTRHEQAAVHAADGYARASGKVGVAIVTSGPGFTNA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 150 IGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLP 229
Cdd:PRK08527 82 VTGLATAYMDSIPLVLISGQVPNSLIGTDAFQEIDAVGISRPCVKHNYLVKSIEELPRILKEAFYIARSGRPGPVHIDIP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 230 GNlvLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATP 307
Cdd:PRK08527 162 KD--VTATLGEFEYPKEISLKTykPTYKGNSRQIKKAAEAIKEAKKPLFYLGGGAILSN-ASEEIRELVKKTGIPAVETL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 308 GGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPL 380
Cdd:PRK08527 239 MARGVLRSDDPLLLGMlgmhgsyAANMAMSECDLLISLGARFDDRVT-GKLSEFAKHAKIIHVDIDPSSISKIVNADYPI 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 381 LGDIGETLAELTPRLGDWTYDESTEWFKKLRENAEKNRAAVEkfvdDHSTPLNYYAAYQPIREFLANNDVIvineganTM 460
Cdd:PRK08527 318 VGDLKNVLKEMLEELKEENPTTYKEWREILKRYNELHPLSYE----DSDEVLKPQWVIERVGELLGDDAII-------ST 386
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 461 DIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVV 534
Cdd:PRK08527 387 DVGQHQMwvaqfyPFNYPRQLATSGGLGTM----GYGLPAALGAKLAVPDKVVINFTGDGSILMNIQELMTAVEYKIPVI 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 535 TVIINNSgiYRGLLPEDDKAIEGDRtlaLPVLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKtDGPTVINAL 614
Cdd:PRK08527 463 NIILNNN--FLGMVRQWQTFFYEER---YSETDLSTQPDFVKLAESFGGIGFRVTTKEEFDKALKEALES-DKVALIDVK 536
|
.
gi 17531301 615 I 615
Cdd:PRK08527 537 I 537
|
|
| PRK06276 |
PRK06276 |
acetolactate synthase large subunit; |
72-619 |
5.81e-55 |
|
acetolactate synthase large subunit;
Pssm-ID: 235766 [Multi-domain] Cd Length: 586 Bit Score: 196.90 E-value: 5.81e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK06276 1 MKGAEAIIKALEAEGVKIIFGYPGGALLPFYDALYDSDLIHILTRHEQAAAHAADGYARASGKVGVCVATSGPGATNLVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGN 231
Cdd:PRK06276 81 GIATAYADSSPVIALTGQVPTKLIGNDAFQEIDALGIFMPITKHNFQIKKPEEIPEIFRAAFEIAKTGRPGPVHIDLPKD 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 232 LV-LTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSerGAT----QVQQFLtksKLPWL 304
Cdd:PRK06276 161 VQeGELDLEKYPIPAKIDLPGykPTTFGHPLQIKKAAELIAEAERPVILAGGGVIIS--GASeeliELSELV---KIPVC 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 305 ATPGGKGVASDLHPRFIG-------QARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTE 377
Cdd:PRK06276 236 TTLMGKGAFPEDHPLALGmvgmhgtKAANYSVTESDVLIAIGCRFSDRTT-GDISSFAPNAKIIHIDIDPAEIGKNVRVD 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 378 VPLLGDIGETLAELTPRLGDWTYDESTEWFkklrENAEKNRAAVEKFVDDHSTPLNyyaAYQPIREFLAN-NDVIVINEG 456
Cdd:PRK06276 315 VPIVGDAKNVLRDLLAELMKKEIKNKSEWL----ERVKKLKKESIPRMDFDDKPIK---PQRVIKELMEVlREIDPSKNT 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 457 ANTMDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYN 530
Cdd:PRK06276 388 IITTDVGQNQMwmahffKTSAPRSFISSGGLGTM----GFGFPAAIGAKVAKPDANVIAITGDGGFLMNSQELATIAEYD 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 531 LPVVTVIINNSGIyrGLLPEDDKAIEGDRTLAlpvLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFqKTDGPTV 610
Cdd:PRK06276 464 IPVVICIFDNRTL--GMVYQWQNLYYGKRQSE---VHLGETPDFVKLAESYGVKADRVEKPDEIKEALKEAI-KSGEPYL 537
|
....*....
gi 17531301 611 INALISTDS 619
Cdd:PRK06276 538 LDIIIDPAE 546
|
|
| PRK08617 |
PRK08617 |
acetolactate synthase AlsS; |
71-612 |
6.71e-54 |
|
acetolactate synthase AlsS;
Pssm-ID: 236312 [Multi-domain] Cd Length: 552 Bit Score: 193.15 E-value: 6.71e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 71 NMDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK08617 4 KKYGADLVVDSLINQGVKYVFGIPGAKIDRVFDALEDSGPELIVTRHEQNAAFMAAAIGRLTGKPGVVLVTSGPGVSNLA 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGT---ADV------DLENRGAFQewsqqeSVRNSCKHVSRPtslHTIPAHIEKAVRCAMYGRP 221
Cdd:PRK08617 84 TGLVTATAEGDPVVAIGGQvkrADRlkrthqSMDNVALFR------PITKYSAEVQDP---DNLSEVLANAFRAAESGRP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 222 GAVYVDLPGNLvltsTEEEISFPPQVPLPAPV-SIPPIAEIEKAIDTLKSAKKPLVIVGKGAAwSERGATQVQQFLTKSK 300
Cdd:PRK08617 155 GAAFVSLPQDV----VDAPVTSKAIAPLSKPKlGPASPEDINYLAELIKNAKLPVLLLGMRAS-SPEVTAAIRRLLERTN 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 301 LPWLATPGGKGVAS-DLHPRFIG-------QARSLALREADTVFLIG-------ARfNWIlhfglpprFQKDVKVVQIDI 365
Cdd:PRK08617 230 LPVVETFQAAGVISrELEDHFFGrvglfrnQPGDELLKKADLVITIGydpieyePR-NWN--------SEGDATIIHIDV 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 366 CPEEFHQNVKTEVPLLGDIGETLAELTPRLGDWTY-DESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIref 444
Cdd:PRK08617 301 LPAEIDNYYQPERELIGDIAATLDLLAEKLDGLSLsPQSLEILEELRAQLEELAERPARLEEGAVHPLRIIRALQDI--- 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 445 lANNDVIVineganTMDIG---------------RTMMPSRlpkrrldagtfG--TMGVGHGFSLAAALwARdhsPKTKV 507
Cdd:PRK08617 378 -VTDDTTV------TVDVGshyiwmaryfrsyepRHLLFSN-----------GmqTLGVALPWAIAAAL-VR---PGKKV 435
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 508 LVVQGDSAFGFSAMELETIARYNLPVVTVIINN-----------------SGIYRGllPEDDKAiegdrtlalpvlslta 570
Cdd:PRK08617 436 VSVSGDGGFLFSAMELETAVRLKLNIVHIIWNDghynmvefqeemkygrsSGVDFG--PVDFVK---------------- 497
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 17531301 571 ecrYEEmckAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVIN 612
Cdd:PRK08617 498 ---YAE---SFGAKGLRVTSPDELEPVLREALA-TDGPVVID 532
|
|
| PRK06725 |
PRK06725 |
acetolactate synthase large subunit; |
72-612 |
8.45e-54 |
|
acetolactate synthase large subunit;
Pssm-ID: 180672 [Multi-domain] Cd Length: 570 Bit Score: 193.26 E-value: 8.45e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK06725 15 VTGAGHVIQCLKKLGVTTVFGYPGGAILPVYDALYESGLKHILTRHEQAAIHAAEGYARASGKVGVVFATSGPGATNLVT 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGN 231
Cdd:PRK06725 95 GLADAYMDSIPLVVITGQVATPLIGKDGFQEADVVGITVPVTKHNYQVRDVNQLSRIVQEAFYIAESGRPGPVLIDIPKD 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 232 L----VLTSTEEEISFPPQVPLPAPVSIpPIAEIEKAIdtlKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATP 307
Cdd:PRK06725 175 VqnekVTSFYNEVVEIPGYKPEPRPDSM-KLREVAKAI---SKAKRPLLYIGGGVIHSG-GSEELIEFARENRIPVVSTL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 308 GGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPL 380
Cdd:PRK06725 250 MGLGAYPPGDPLFLGMlgmhgtyAANMAVTECDLLLALGVRFDDRVT-GKLELFSPHSKKVHIDIDPSEFHKNVAVEYPV 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 381 LGDIGETLAELTPRLGdwtYDESTEWFKKLRENAEKnraavekfvddhsTPLNYYAAY-----QPIREF---LANNDVIV 452
Cdd:PRK06725 329 VGDVKKALHMLLHMSI---HTQTDEWLQKVKTWKEE-------------YPLSYKQKEselkpQHVINLvseLTNGEAIV 392
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 453 ineganTMDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETI 526
Cdd:PRK06725 393 ------TTEVGQHQMwaahfyKAKNPRTFLTSGGLGTM----GFGFPAAIGAQLAKEEELVICIAGDASFQMNIQELQTI 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 527 ARYNLPVVTVIINNSgiYRGLLPEDDKAIEGDRTLAlpvlSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKtD 606
Cdd:PRK06725 463 AENNIPVKVFIINNK--FLGMVRQWQEMFYENRLSE----SKIGSPDFVKVAEAYGVKGLRATNSTEAKQVMLEAFAH-E 535
|
....*.
gi 17531301 607 GPTVIN 612
Cdd:PRK06725 536 GPVVVD 541
|
|
| PRK08322 |
PRK08322 |
acetolactate synthase large subunit; |
72-612 |
3.97e-52 |
|
acetolactate synthase large subunit;
Pssm-ID: 236239 [Multi-domain] Cd Length: 547 Bit Score: 188.11 E-value: 3.97e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK08322 1 MKAADLFVKCLENEGVEYIFGIPGEENLDLLEALRDSSIKLILTRHEQGAAFMAATYGRLTGKAGVCLSTLGPGATNLVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQ------------EWSQQesvrnsckhVSRPTslhTIPAHIEKAVRCAMYG 219
Cdd:PRK08322 81 GVAYAQLGGMPMVAITGQKPIKRSKQGSFQivdvvammapltKWTRQ---------IVSPD---NIPEVVREAFRLAEEE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 220 RPGAVYVDLPGNLVLTSTEEeisfppqVPLPAPVSIPPIAE---IEKAIDTLKSAKKPLVIVGKGAAwseRGAT--QVQQ 294
Cdd:PRK08322 149 RPGAVHLELPEDIAAEETDG-------KPLPRSYSRRPYASpkaIERAAEAIQAAKNPLILIGAGAN---RKTAskALTE 218
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 295 FLTKSKLPWLATPGGKGVASDLHPRFIG----QAR---SLALREADTVFLIGARfnwILHFglPPRF---QKDVKVVQID 364
Cdd:PRK08322 219 FVDKTGIPFFTTQMGKGVIPETHPLSLGtaglSQGdyvHCAIEHADLIINVGHD---VIEK--PPFFmnpNGDKKVIHIN 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 365 ICPEEF--HQNVKTEVplLGDIGETLAELTPRLGDwTYDESTEWFKKLRENaekNRAAVEKFVDDHSTPLNYYAAYQPIR 442
Cdd:PRK08322 294 FLPAEVdpVYFPQVEV--VGDIANSLWQLKERLAD-QPHWDFPRFLKIREA---IEAHLEEGADDDRFPMKPQRIVADLR 367
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 443 EFLANNDVIVINEGANTMDIGRtMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALWArdhsPKTKVLVVQGDSAFGFSAME 522
Cdd:PRK08322 368 KVMPDDDIVILDNGAYKIWFAR-NYRAYEPNTCLLDNALATMGAGLPSAIAAKLVH----PDRKVLAVCGDGGFMMNSQE 442
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 523 LETIARYNLPVVTVIINNSGiYrGLLpEDDKAIEGDRTLAL----PVLSLTAEcryeemckAFGGAGTVVRTVPEIKAAL 598
Cdd:PRK08322 443 LETAVRLGLPLVVLILNDNA-Y-GMI-RWKQENMGFEDFGLdfgnPDFVKYAE--------SYGAKGYRVESADDLLPTL 511
|
570
....*....|....
gi 17531301 599 EKAFqKTDGPTVIN 612
Cdd:PRK08322 512 EEAL-AQPGVHVID 524
|
|
| PRK06882 |
PRK06882 |
acetolactate synthase 3 large subunit; |
72-606 |
3.38e-51 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 168717 [Multi-domain] Cd Length: 574 Bit Score: 186.27 E-value: 3.38e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQA-HGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK06882 4 LSGAEMVVQSLRDEGVEYVFGYPGGSVLDIYDAIHTlGGIEHVLVRHEQAAVHMADGYARSTGKVGCVLVTSGPGATNAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:PRK06882 84 TGIATAYTDSVPLVILSGQVPSNLIGTDAFQECDMLGISRPVVKHSFIVKNAEDIPSTIKKAFYIASTGRPGPVVIDIPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NLVLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPG 308
Cdd:PRK06882 164 DMVNPANKFTYEYPEEVSLRSynPTVQGHKGQIKKALKALLVAKKPVLFVGGGVITAE-CSEQLTQFAQKLNLPVTSSLM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHFGLpPRFQKDVKVVQIDICPEEFHQNVKTEVPLL 381
Cdd:PRK06882 243 GLGAYPSTDKQFLGMlgmhgtyEANNAMHESDLILGIGVRFDDRTTNNL-AKYCPNAKVIHIDIDPTSISKNVPAYIPIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLAELTPRLGDWTYDES----TEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQpirefLANNDVIVINega 457
Cdd:PRK06882 322 GSAKNVLEEFLSLLEEENLAKSqtdlTAWWQQINEWKAKKCLEFDRTSDVIKPQQVVEAIYR-----LTNGDAYVAS--- 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 458 ntmDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNL 531
Cdd:PRK06882 394 ---DVGQHQMfaalhyPFDKPRRWINSGGAGTM----GFGLPAAIGVKFAHPEATVVCVTGDGSIQMNIQELSTAKQYDI 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17531301 532 PVVTVIINNSgiYRGLLPEDDKAIEGDRTLALPVLSLTaecRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKTD 606
Cdd:PRK06882 467 PVVIVSLNNR--FLGMVKQWQDLIYSGRHSQVYMNSLP---DFAKLAEAYGHVGIQIDTPDELEEKLTQAFSIKD 536
|
|
| PRK08978 |
PRK08978 |
acetolactate synthase 2 catalytic subunit; Reviewed |
72-541 |
1.30e-50 |
|
acetolactate synthase 2 catalytic subunit; Reviewed
Pssm-ID: 181601 [Multi-domain] Cd Length: 548 Bit Score: 183.93 E-value: 1.30e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK08978 1 MNGAQWVVHALRAQGVDTVFGYPGGAIMPVYDALYDGGVEHLLCRHEQGAAMAAIGYARATGKVGVCIATSGPGATNLIT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQE-----WSQqesvrnSC-KHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVY 225
Cdd:PRK08978 81 GLADALLDSVPVVAITGQVSSPLIGTDAFQEidvlgLSL------ACtKHSFLVQSLEELPEIMAEAFEIASSGRPGPVL 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 226 VDLPGNLVLTSTEEEISFPPQVPLPApvsiPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSerGAT-QVQQFLTKSKLPWL 304
Cdd:PRK08978 155 VDIPKDIQLAEGELEPHLTTVENEPA----FPAAELEQARALLAQAKKPVLYVGGGVGMA--GAVpALREFLAATGMPAV 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 305 ATPGGKGVASDLHPRFIG-------QARSLALREADTVFLIGARFNwilhfglpPR-------FQKDVKVVQIDICPEEF 370
Cdd:PRK08978 229 ATLKGLGAVEADHPYYLGmlgmhgtKAANLAVQECDLLIAVGARFD--------DRvtgklntFAPHAKVIHLDIDPAEI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 371 HQNVKTEVPLLGDIGETLAELTPRLgdwtydESTEWFKKLRENAEKNraaveKFVDDHSTPLNYYAAY-QPIREFLANND 449
Cdd:PRK08978 301 NKLRQAHVALQGDLNALLPALQQPL------NIDAWRQHCAQLRAEH-----AWRYDHPGEAIYAPALlKQLSDRKPADT 369
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 450 VIVINEGANTMDIGRTMMPSRlPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARY 529
Cdd:PRK08978 370 VVTTDVGQHQMWVAQHMRFTR-PENFITSSGLGTM----GFGLPAAIGAQVARPDDTVICVSGDGSFMMNVQELGTIKRK 444
|
490
....*....|..
gi 17531301 530 NLPVVTVIINNS 541
Cdd:PRK08978 445 QLPVKIVLLDNQ 456
|
|
| PRK07710 |
PRK07710 |
acetolactate synthase large subunit; |
72-623 |
1.39e-50 |
|
acetolactate synthase large subunit;
Pssm-ID: 236076 [Multi-domain] Cd Length: 571 Bit Score: 184.58 E-value: 1.39e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK07710 16 MTGAQMLIEALEKEGVEVIFGYPGGAVLPLYDALYDCGIPHILTRHEQGAIHAAEGYARISGKPGVVIATSGPGATNVVT 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGN 231
Cdd:PRK07710 96 GLADAMIDSLPLVVFTGQVATSVIGSDAFQEADIMGITMPVTKHNYQVRKASDLPRIIKEAFHIATTGRPGPVLIDIPKD 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 232 LVLtsTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSeRGATQVQQFLTKSKLPWLATPGG 309
Cdd:PRK07710 176 MVV--EEGEFCYDVQMDLPGyqPNYEPNLLQIRKLVQAVSVAKKPVILAGAGVLHA-KASKELTSYAEQQEIPVVHTLLG 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 310 KGVASDLHPRFIGQA-------RSLALREADTVFLIGARFNWILHFGLpPRFQKDVKVVQIDICPEEFHQNVKTEVPLLG 382
Cdd:PRK07710 253 LGGFPADHPLFLGMAgmhgtytANMALYECDLLINIGARFDDRVTGNL-AYFAKEATVAHIDIDPAEIGKNVPTEIPIVA 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 383 DIGETLAELTPRLGDwtYDESTEWFKKLRENAEKnraaVEKFVDDHSTPLNYYAAYQPIREFlANNDVIVineganTMDI 462
Cdd:PRK07710 332 DAKQALQVLLQQEGK--KENHHEWLSLLKNWKEK----YPLSYKRNSESIKPQKAIEMLYEI-TKGEAIV------TTDV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 463 GRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTV 536
Cdd:PRK07710 399 GQHQMwaaqyyPFKTPDKWVTSGGLGTM----GFGLPAAIGAQLAKPDETVVAIVGDGGFQMTLQELSVIKELSLPVKVV 474
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 537 IINNSGIyrGLLPE-DDKAIEGDRTLALpvlsLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVINALI 615
Cdd:PRK07710 475 ILNNEAL--GMVRQwQEEFYNQRYSHSL----LSCQPDFVKLAEAYGIKGVRIDDELEAKEQLQHAIE-LQEPVVIDCRV 547
|
....*...
gi 17531301 616 STDSERKP 623
Cdd:PRK07710 548 LQSEKVMP 555
|
|
| PRK08266 |
PRK08266 |
hypothetical protein; Provisional |
72-623 |
1.14e-49 |
|
hypothetical protein; Provisional
Pssm-ID: 181337 [Multi-domain] Cd Length: 542 Bit Score: 181.36 E-value: 1.14e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEV--GMAAQAHGIKYIGCRNEqaAAYAAQAMGY--LTGKPVALLVVSGPGIL 147
Cdd:PRK08266 4 MTGGEAIVAGLVAHGVDTVFGLPGAQLYWLfdALYKAGDRIRVIHTRHE--QAAGYMAFGYarSTGRPGVCSVVPGPGVL 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGGTADVDL--ENRGAFQEWSQQ-ESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAV 224
Cdd:PRK08266 82 NAGAALLTAYGCNSPVLCLTGQIPSALigKGRGHLHEMPDQlATLRSFTKWAERIEHPSEAPALVAEAFQQMLSGRPRPV 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 225 YVDLPGNlVLTSTEEEISFPPQVPLPAPvSIPPIAeIEKAIDTLKSAKKPLVIVGKGA--AWSErgatqVQQFLTKSKLP 302
Cdd:PRK08266 162 ALEMPWD-VFGQRAPVAAAPPLRPAPPP-APDPDA-IAAAAALIAAAKNPMIFVGGGAagAGEE-----IRELAEMLQAP 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 303 WLATPGGKGVASDLHPRFIGQARSLAL-READTVFLIGARFnwILHFGLPPRFQKDVKVVQIDICPEEfHQNVKTEVPLL 381
Cdd:PRK08266 234 VVAFRSGRGIVSDRHPLGLNFAAAYELwPQTDVVIGIGSRL--ELPTFRWPWRPDGLKVIRIDIDPTE-MRRLKPDVAIV 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLAELTPRLGDWTYDES--TEWFKKLRENAEKNRAAVEkfvddhstP-LNYYAAyqpIREFLAnNDVIVINEGAN 458
Cdd:PRK08266 311 ADAKAGTAALLDALSKAGSKRPsrRAELRELKAAARQRIQAVQ--------PqASYLRA---IREALP-DDGIFVDELSQ 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 459 TMDIGRTMMPSRLPKRRLDAGTFGTMgvGHGFslAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVII 538
Cdd:PRK08266 379 VGFASWFAFPVYAPRTFVTCGYQGTL--GYGF--PTALGAKVANPDRPVVSITGDGGFMFGVQELATAVQHNIGVVTVVF 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 539 NNSgiYRGLLPEDDKAIEGDRTLAlpvlsltAECRYEEMCK---AFGGAGTVVRTVPEIKAALEKAFQKtDGPTVINALI 615
Cdd:PRK08266 455 NNN--AYGNVRRDQKRRFGGRVVA-------SDLVNPDFVKlaeSFGVAAFRVDSPEELRAALEAALAH-GGPVLIEVPV 524
|
....*...
gi 17531301 616 STDSERKP 623
Cdd:PRK08266 525 PRGSEASP 532
|
|
| PRK08611 |
PRK08611 |
pyruvate oxidase; Provisional |
75-618 |
4.07e-49 |
|
pyruvate oxidase; Provisional
Pssm-ID: 181502 [Multi-domain] Cd Length: 576 Bit Score: 180.58 E-value: 4.07e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 75 ASITAA-----ALKSQGVEYMFGVVGFPVIEV--GMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGIL 147
Cdd:PRK08611 2 AKIKAGealvkLLQDWGIDHVYGIPGDSIDAVvdALRKEQDKIKFIQVRHEEVAALAAAAYAKLTGKIGVCLSIGGPGAI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQE-----SVRNscKHVSRPTSLhtiPAHIEKAVRCAmYGRPG 222
Cdd:PRK08611 82 HLLNGLYDAKMDHVPVLALAGQVTSDLLGTDFFQEVNLEKmfedvAVYN--HQIMSAENL---PEIVNQAIRTA-YEKKG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 223 -AVYV---DLPGNLVLTSTEEEIS-FPPQVPLPAPvsippiAEIEKAIDTLKSAKKPLVIVGKGAawsERGATQVQQFLT 297
Cdd:PRK08611 156 vAVLTipdDLPAQKIKDTTNKTVDtFRPTVPSPKP------KDIKKAAKLINKAKKPVILAGLGA---KHAKEELLAFAE 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 298 KSKLPWLATPGGKGVASDLHPRFIGQARSL-------ALREADTVFLIGARFNWILHfgLPprfqKDVKVVQIDICPEEF 370
Cdd:PRK08611 227 KAKIPIIHTLPAKGIIPDDHPYSLGNLGKIgtkpayeAMQEADLLIMVGTNYPYVDY--LP----KKAKAIQIDTDPANI 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 371 HQNVKTEVPLLGDIGETLAELTPRLgdwTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDV 450
Cdd:PRK08611 301 GKRYPVNVGLVGDAKKALHQLTENI---KHVEDRRFLEACQENMAKWWKWMEEDENNASTPIKPERVMAAIQKIADDDAV 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 451 IVINEGANTMDIGR--TMMPSrlpKRRLDAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIAR 528
Cdd:PRK08611 378 LSVDVGTVTVWSARylNLGTN---QKFIISSWLGTMGCG----LPGAIAAKIAFPDRQAIAICGDGGFSMVMQDFVTAVK 450
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 529 YNLPVVTVIINNSGI----YrgllpEDDKAIEGDRTLALPVLSLTaecRYEEMCkafGGAGTVVRTVPEIKAALEKAFQk 604
Cdd:PRK08611 451 YKLPIVVVVLNNQQLafikY-----EQQAAGELEYAIDLSDMDYA---KFAEAC---GGKGYRVEKAEELDPAFEEALA- 518
|
570
....*....|....
gi 17531301 605 TDGPTVINALISTD 618
Cdd:PRK08611 519 QDKPVIIDVYVDPN 532
|
|
| PRK06048 |
PRK06048 |
acetolactate synthase large subunit; |
72-623 |
1.11e-48 |
|
acetolactate synthase large subunit;
Pssm-ID: 180368 [Multi-domain] Cd Length: 561 Bit Score: 178.82 E-value: 1.11e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIG 151
Cdd:PRK06048 8 MTGARAIIKCLEKEGVEVIFGYPGGAIIPVYDELYDSDLRHILVRHEQAAAHAADGYARATGKVGVCVATSGPGATNLVT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 152 GLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGN 231
Cdd:PRK06048 88 GIATAYMDSVPIVALTGQVPRSMIGNDAFQEADITGITMPITKHNYLVQDAKDLPRIIKEAFHIASTGRPGPVLIDLPKD 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 232 lvLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPGG 309
Cdd:PRK06048 168 --VTTAEIDFDYPDKVELRGykPTYKGNPQQIKRAAELIMKAERPIIYAGGGVISSN-ASEELVELAETIPAPVTTTLMG 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 310 KGVASDLHPRFIG-------QARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLG 382
Cdd:PRK06048 245 IGAIPTEHPLSLGmlgmhgtKYANYAIQESDLIIAVGARFDDRVT-GKLASFAPNAKIIHIDIDPAEISKNVKVDVPIVG 323
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 383 DIGETLAELTPRLgdwTYDESTEWFKKLRENAEKnraavekfvddhsTPLNYYAAYQPIR-EFL------ANNDVIVINE 455
Cdd:PRK06048 324 DAKQVLKSLIKYV---QYCDRKEWLDKINQWKKE-------------YPLKYKEREDVIKpQYVieqiyeLCPDAIIVTE 387
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 456 -GANTMDIGRtMMPSRLPKRRLDAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVV 534
Cdd:PRK06048 388 vGQHQMWAAQ-YFKYKYPRTFITSGGLGTMGYG----FPAAIGAKVGKPDKTVIDIAGDGSFQMNSQELATAVQNDIPVI 462
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 535 TVIINNSgiYRGLLPEDDKAIEGDRTLAlpvLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVINAL 614
Cdd:PRK06048 463 VAILNNG--YLGMVRQWQELFYDKRYSH---TCIKGSVDFVKLAEAYGALGLRVEKPSEVRPAIEEAVA-SDRPVVIDFI 536
|
....*....
gi 17531301 615 ISTDSERKP 623
Cdd:PRK06048 537 VECEENVSP 545
|
|
| PRK07282 |
PRK07282 |
acetolactate synthase large subunit; |
74-540 |
1.25e-47 |
|
acetolactate synthase large subunit;
Pssm-ID: 180919 [Multi-domain] Cd Length: 566 Bit Score: 176.17 E-value: 1.25e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASITAAALKSQGVEYMFGVVGFPVIEVGMAA-QAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGG 152
Cdd:PRK07282 12 GSDLVLETLRDLGVDTIFGYPGGAVLPLYDAIyNFEGIRHILARHEQGALHEAEGYAKSTGKLGVAVVTSGPGATNAITG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 153 LANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGNL 232
Cdd:PRK07282 92 IADAMSDSVPLLVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQIRETADIPRIITEAVHIATTGRPGPVVIDLPKDV 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 233 vltsTEEEISF--PPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPG 308
Cdd:PRK07282 172 ----SALETDFiyDPEVNLPSyqPTLEPNDMQIKKILKQLSKAKKPVILAGGGINYAE-AATELNAFAERYQIPVVTTLL 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILhFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLL 381
Cdd:PRK07282 247 GQGTIATSHPLFLGMggmhgsyAANIAMTEADFMINIGSRFDDRL-TGNPKTFAKNAKVAHIDIDPAEIGKIIKTDIPVV 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLAELTPRlgDWTYDESTEWFKKLRENaeKNRAAVEKFVDDHSTPlnyYAAYQPIREfLANNDVIVINegantmD 461
Cdd:PRK07282 326 GDAKKALQMLLAE--PTVHNNTEKWIEKVTKD--KNRVRSYDKKERVVQP---QAVIERIGE-LTNGDAIVVT------D 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 462 IGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVT 535
Cdd:PRK07282 392 VGQHQMwaaqyyPYQNERQLVTSGGLGTM----GFGIPAAIGAKIANPDKEVILFVGDGGFQMTNQELAILNIYKVPIKV 467
|
....*
gi 17531301 536 VIINN 540
Cdd:PRK07282 468 VMLNN 472
|
|
| PRK06466 |
PRK06466 |
acetolactate synthase 3 large subunit; |
72-632 |
2.71e-46 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 180578 [Multi-domain] Cd Length: 574 Bit Score: 172.62 E-value: 2.71e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAA-QAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK06466 4 LSGAEMLVRALRDEGVEYIYGYPGGAVLHIYDALfKQDKVEHILVRHEQAATHMADGYARATGKTGVVLVTSGPGATNAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEwsqqesvrNSCKHVSRPTSLHT--------IPAHIEKAVRCAMYGRPG 222
Cdd:PRK06466 84 TGIATAYMDSIPMVVLSGQVPSTLIGEDAFQE--------TDMVGISRPIVKHSfmvkhaseIPEIIKKAFYIAQSGRPG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 223 AVYVDLPGNLVLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSeRGATQVQQFLTKSK 300
Cdd:PRK06466 156 PVVVDIPKDMTNPAEKFEYEYPKKVKLRSysPAVRGHSGQIRKAVEMLLAAKRPVIYSGGGVVLG-NASALLTELAHLLN 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 301 LPWLATPGGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHFGlPPRFQKDVKVVQIDICPEEFHQN 373
Cdd:PRK06466 235 LPVTNTLMGLGGFPGTDRQFLGMlgmhgtyEANMAMHHADVILAVGARFDDRVTNG-PAKFCPNAKIIHIDIDPASISKT 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 374 VKTEVPLLGDIGETLAELTPRLG--DWTYDEST--EWFKKLREnaEKNRAAVEKFVDDHSTPLNYYAAYQPIREfLANND 449
Cdd:PRK06466 314 IKADIPIVGPVESVLTEMLAILKeiGEKPDKEAlaAWWKQIDE--WRGRHGLFPYDKGDGGIIKPQQVVETLYE-VTNGD 390
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 450 VIVineganTMDIGRTMMPSRL------PKRRLDAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMEL 523
Cdd:PRK06466 391 AYV------TSDVGQHQMFAAQyykfnkPNRWINSGGLGTMGFG----LPAAMGVKLAFPDQDVACVTGEGSIQMNIQEL 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 524 ETIARYNLPVVTVIINNSGIyrGLLPE-DDKAIEGDRTL----ALPVLSLTAEcryeemckAFGGAGTVVRTVPEIKAAL 598
Cdd:PRK06466 461 STCLQYGLPVKIINLNNGAL--GMVRQwQDMQYEGRHSHsymeSLPDFVKLAE--------AYGHVGIRITDLKDLKPKL 530
|
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 17531301 599 EKAFQKTDGPTVINALISTDSERKPQA-------DHWLTRS 632
Cdd:PRK06466 531 EEAFAMKDRLVFIDIYVDRSEHVYPMQiadgsmrDMWLSKT 571
|
|
| PRK08979 |
PRK08979 |
acetolactate synthase 3 large subunit; |
72-606 |
3.16e-46 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181602 [Multi-domain] Cd Length: 572 Bit Score: 172.31 E-value: 3.16e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAH-GIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK08979 4 LSGASMIVRSLIDEGVKHIFGYPGGSVLDIYDALHEKsGIEHILVRHEQAAVHMADGYARATGKVGVVLVTSGPGATNTI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:PRK08979 84 TGIATAYMDSIPMVVLSGQVPSNLIGNDAFQECDMIGISRPVVKHSFLVKDAEDIPEIIKKAFYIASTGRPGPVVIDLPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NLVLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSERGAtQVQQFLTKSKLPWLATPG 308
Cdd:PRK08979 164 DCLNPAILHPYEYPESIKMRSynPTTSGHKGQIKRGLQALLAAKKPVLYVGGGAIISGADK-QILQLAEKLNLPVVSTLM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHFGLpPRFQKDVKVVQIDICPEEFHQNVKTEVPLL 381
Cdd:PRK08979 243 GLGAFPGTHKNSLGMlgmhgryEANMAMHNADLIFGIGVRFDDRTTNNL-EKYCPNATILHIDIDPSSISKTVRVDIPIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLAELTPRLGDW--TYDES--TEWFKKLRENAEKNRAAVEKfVDDHSTPlnyyaaYQPIREF--LANNDVIVine 455
Cdd:PRK08979 322 GSADKVLDSMLALLDESgeTNDEAaiASWWNEIEVWRSRNCLAYDK-SSERIKP------QQVIETLykLTNGDAYV--- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 456 ganTMDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARY 529
Cdd:PRK08979 392 ---ASDVGQHQMfaalyyPFDKPRRWINSGGLGTM----GFGLPAAMGVKFAMPDETVVCVTGDGSIQMNIQELSTALQY 464
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 530 NLPVVTVIINNSgiYRGLLPEDDKAIEGDR-----TLALPVLSLTAEcryeemckAFGGAGTVVRTVPEIKAALEKAFQK 604
Cdd:PRK08979 465 DIPVKIINLNNR--FLGMVKQWQDMIYQGRhshsyMDSVPDFAKIAE--------AYGHVGIRISDPDELESGLEKALAM 534
|
..
gi 17531301 605 TD 606
Cdd:PRK08979 535 KD 536
|
|
| TPP_enzyme_N |
pfam02776 |
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain; |
74-240 |
2.77e-45 |
|
Thiamine pyrophosphate enzyme, N-terminal TPP binding domain;
Pssm-ID: 460690 [Multi-domain] Cd Length: 169 Bit Score: 158.55 E-value: 2.77e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAH-GIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGG 152
Cdd:pfam02776 1 GAEALADVLKALGVDTVFGVPGGHILPLLDALAKSpGIRYVLTRHEQGAAFAADGYARATGKPGVVLVTSGPGATNALTG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 153 LANATVNCWPVVCIGGTADVDLENRGAFQ-EWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGN 231
Cdd:pfam02776 81 LANAYVDSVPLLVISGQRPRSLVGRGALQqELDQLALFRPVTKWAVRVTSADEIPEVLRRAFRAALSGRPGPVYLEIPLD 160
|
....*....
gi 17531301 232 LVLTSTEEE 240
Cdd:pfam02776 161 VLLEEVDED 169
|
|
| PRK08155 |
PRK08155 |
acetolactate synthase large subunit; |
72-622 |
5.18e-45 |
|
acetolactate synthase large subunit;
Pssm-ID: 181257 [Multi-domain] Cd Length: 564 Bit Score: 168.73 E-value: 5.18e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMA-AQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK08155 13 FTGAELIVRLLERQGIRIVTGIPGGAILPLYDAlSQSTQIRHILARHEQGAGFIAQGMARTTGKPAVCMACSGPGATNLV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:PRK08155 93 TAIADARLDSIPLVCITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRDIEELPQVISDAFRIAQSGRPGPVWIDIPK 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NlvLTSTEEEISFPPQVPLPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPGGK 310
Cdd:PRK08155 173 D--VQTAVIELEALPAPAEKDAAPAFDEESIRDAAAMINAAKRPVLYLGGGVINSG-APARARELAEKAQLPTTMTLMAL 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 311 GVASDLHPRFIGQ-----ARS--LALREADTVFLIGARFNwILHFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLGD 383
Cdd:PRK08155 250 GMLPKAHPLSLGMlgmhgARStnYILQEADLLIVLGARFD-DRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQAD 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 384 IGETLAELTPRLGDwtyDESTEWFKKLRENAEKNRAAVEKfVDDhstPLNYYAAYQPIREFLANNDVIvineganTMDIG 463
Cdd:PRK08155 329 VDDVLAQLLPLVEA---QPRAEWHQLVADLQREFPCPIPK-ADD---PLSHYGLINAVAACVDDNAII-------TTDVG 394
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 464 RTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVI 537
Cdd:PRK08155 395 QHQMwtaqayPLNRPRQWLTSGGLGTM----GFGLPAAIGAALANPERKVLCFSGDGSLMMNIQEMATAAENQLDVKIIL 470
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 538 INNSGIyrGLLPEDDKAIEGDRTLALPVLSLTAECRYEEmckAFGGAGTVVRTVPEIKAALEKAFQKTdGPTVINALIst 617
Cdd:PRK08155 471 MNNEAL--GLVHQQQSLFYGQRVFAATYPGKINFMQIAA---GFGLETCDLNNEADPQAALQEAINRP-GPALIHVRI-- 542
|
....*
gi 17531301 618 DSERK 622
Cdd:PRK08155 543 DAEEK 547
|
|
| PRK06154 |
PRK06154 |
thiamine pyrophosphate-requiring protein; |
68-606 |
7.38e-45 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 235718 [Multi-domain] Cd Length: 565 Bit Score: 168.07 E-value: 7.38e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 68 DGSNMDGASITAAALKSQGVEYMFGvvgFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLT-GKPVALLVVS-GPG 145
Cdd:PRK06154 16 EAKTMKVAEAVAEILKEEGVELLFG---FPVNELFDAAAAAGIRPVIARTERVAVHMADGYARATsGERVGVFAVQyGPG 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 146 ILHAIGGLANATVNCWPVVCIGGTADVDLEN-RGAFQEWSQQESVRNSCKHVSRPTSLhtiPAHIEKAVRCAMYGRPGAV 224
Cdd:PRK06154 93 AENAFGGVAQAYGDSVPVLFLPTGYPRGSTDvAPNFESLRNYRHITKWCEQVTLPDEV---PELMRRAFTRLRNGRPGPV 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 225 YVDLPGNLVltstEEEISFPP--QVPLPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLP 302
Cdd:PRK06154 170 VLELPVDVL----AEELDELPldHRPSRRSRPGADPVEVVEAAALLLAAERPVIYAGQGVLYAQ-ATPELKELAELLEIP 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 303 WLATPGGKGVASDLHPRFIGQA-----RSLA--LREADTVFLIGARFNWIlHFGLPprFQKDVKVVQIDICPEEFHQNVK 375
Cdd:PRK06154 245 VMTTLNGKSAFPEDHPLALGSGgrarpATVAhfLREADVLFGIGCSLTRS-YYGLP--MPEGKTIIHSTLDDADLNKDYP 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 376 TEVPLLGDIGETLAELTPRLGDWTYDESTEWFKKLRENAEKNRAAVEKFVD---DHSTPLNYYAAYQPIREFLANNDVIV 452
Cdd:PRK06154 322 IDHGLVGDAALVLKQMIEELRRRVGPDRGRAQQVAAEIEAVRAAWLAKWMPkltSDSTPINPYRVVWELQHAVDIKTVII 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 453 INEGANTMDIGRTMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALwARdhsPKTKVLVVQGDSAFGFSAMELETIARYNLP 532
Cdd:PRK06154 402 THDAGSPRDQLSPFYVASRPGSYLGWGKTTQLGYGLGLAMGAKL-AR---PDALVINLWGDAAFGMTGMDFETAVRERIP 477
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 533 VVTVIINNS--GIYRGLLPEDDKA-----IEGDrtlalpvlsltaecrYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKT 605
Cdd:PRK06154 478 ILTILLNNFsmGGYDKVMPVSTTKyratdISGD---------------YAAIARALGGYGERVEDPEMLVPALLRALRKV 542
|
.
gi 17531301 606 D 606
Cdd:PRK06154 543 K 543
|
|
| PRK06456 |
PRK06456 |
acetolactate synthase large subunit; |
74-611 |
1.87e-44 |
|
acetolactate synthase large subunit;
Pssm-ID: 180569 [Multi-domain] Cd Length: 572 Bit Score: 167.32 E-value: 1.87e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASITAAALKSQGVEYMFGVVGFPVIEVGMA----AQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHA 149
Cdd:PRK06456 4 GARILVDSLKREGVKVIFGIPGLSNMQIYDAfvedLANGELRHVLMRHEQAAAHAADGYARASGVPGVCTATSGPGTTNL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 150 IGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLP 229
Cdd:PRK06456 84 VTGLITAYWDSSPVIAITGQVPRSVMGKMAFQEADAMGVFENVTKYVIGIKRIDEIPQWIKNAFYIATTGRPGPVVIDIP 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 230 GNLVLTSTeEEISFP--PQVP--LPAPVSIPPIaEIEKAIDTLKSAKKPLVIVGKGAAWSerGATqvQQFLTKSKL---P 302
Cdd:PRK06456 164 RDIFYEKM-EEIKWPekPLVKgyRDFPTRIDRL-ALKKAAEILINAERPIILVGTGVVWS--NAT--PEVLELAELlhiP 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 303 WLATPGGKGVASDLHPRFIG-------QARSLALREADTVFLIGARFNWILHFGLPPRFQKDVKVVQIDICPEEFHQNVK 375
Cdd:PRK06456 238 IVSTFPGKTAIPHDHPLYFGpmgyygrAEASMAALESDAMLVVGARFSDRTFTSYDEMVETRKKFIMVNIDPTDGEKAIK 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 376 TEVPLLGDIGETLAEL---TPRLGdwTYDESTEWFKKLRENAEknraAVEKF-VDDHSTPLNYYAAYQPIREFLANNDVI 451
Cdd:PRK06456 318 VDVGIYGNAKIILRELikaITELG--QKRDRSAWLKRVKEYKE----YYSQFyYTEENGKLKPWKIMKTIRQALPRDAIV 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 452 vineganTMDIGRTMMPSRL------PKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELET 525
Cdd:PRK06456 392 -------TTGVGQHQMWAEVfwevlePRTFLTSSGMGTM----GFGLPAAMGAKLARPDKVVVDLDGDGSFLMTGTNLAT 460
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 526 IARYNLPVVTVIINNSGIyrGLLPEDDKAIEGDRTLALPVLSLTAECRYEEmckAFGGAGTVVRTVPEIKAALEKAFqKT 605
Cdd:PRK06456 461 AVDEHIPVISVIFDNRTL--GLVRQVQDLFFGKRIVGVDYGPSPDFVKLAE---AFGALGFNVTTYEDIEKSLKSAI-KE 534
|
....*.
gi 17531301 606 DGPTVI 611
Cdd:PRK06456 535 DIPAVI 540
|
|
| PRK06457 |
PRK06457 |
pyruvate dehydrogenase; Provisional |
75-623 |
7.56e-43 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180570 [Multi-domain] Cd Length: 549 Bit Score: 162.31 E-value: 7.56e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 75 ASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLA 154
Cdd:PRK06457 5 AEVIIRVLEDNGIQRIYGIPGDSIDPLVDAIRKSKVKYVQVRHEEGAALAASVEAKITGKPSACMGTSGPGSIHLLNGLY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 155 NATVNCWPVVCIGGTADVDLENRGAFQEWSQQE-----SVRNscKHVSRPTSLHTIpahIEKAVRCAMYGRpGAVYVDLP 229
Cdd:PRK06457 85 DAKMDHAPVIALTGQVESDMIGHDYFQEVNLTKlfddvAVFN--QILINPENAEYI---IRRAIREAISKR-GVAHINLP 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 230 GNLVLTSTEEEISFPPQVPlpaPVSIPPiaEIEKAIDTLKSAKKPLVIVGKGAawseRGAT-QVQQFLTKSKLPWLATPG 308
Cdd:PRK06457 159 VDILRKSSEYKGSKNTEVG---KVKYSI--DFSRAKELIKESEKPVLLIGGGT----RGLGkEINRFAEKIGAPIIYTLN 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQARSL-------ALREADTVFLIGARFNWIlHFglpprFQKDVKVVQIDICPEEFHQNVKTEVPLL 381
Cdd:PRK06457 230 GKGILPDLDPKVMGGIGLLgtkpsieAMDKADLLIMLGTSFPYV-NF-----LNKSAKVIQVDIDNSNIGKRLDVDLSYP 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLaELTPRlgdwtyDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVIVINEGANTMD 461
Cdd:PRK06457 304 IPVAEFL-NIDIE------EKSDKFYEELKGKKEDWLDSISKQENSLDKPMKPQRVAYIVSQKCKKDAVIVTDTGNVTMW 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 462 IGRTMMPSRLPKRRLDAgTFGTMGVGHGFSLAAALwARDHspKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNS 541
Cdd:PRK06457 377 TARHFRASGEQTFIFSA-WLGSMGIGVPGSVGASF-AVEN--KRQVISFVGDGGFTMTMMELITAKKYDLPVKIIIYNNS 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 542 GIyrGLLPEDDKAI---EGDRTLALPVLSLTAEcryeemckAFGGAGTVVRTVPEIKAALEKaFQKTDGPTVINALISTD 618
Cdd:PRK06457 453 KL--GMIKFEQEVMgypEWGVDLYNPDFTKIAE--------SIGFKGFRLEEPKEAEEIIEE-FLNTKGPAVLDAIVDPN 521
|
....*
gi 17531301 619 SERKP 623
Cdd:PRK06457 522 ERPMP 526
|
|
| PRK07979 |
PRK07979 |
acetolactate synthase 3 large subunit; |
72-604 |
1.03e-42 |
|
acetolactate synthase 3 large subunit;
Pssm-ID: 181185 [Multi-domain] Cd Length: 574 Bit Score: 162.33 E-value: 1.03e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVGFPVIEVGMAAQA-HGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK07979 4 LSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTvGGIDHVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAI 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:PRK07979 84 TGIATAYMDSIPLVVLSGQVATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVDLPK 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NLVLTSTEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSERGAtQVQQFLTKSKLPWLATPG 308
Cdd:PRK07979 164 DILNPANKLPYVWPESVSMRSynPTTQGHKGQIKRALQTLVAAKKPVVYVGGGAINAACHQ-QLKELVEKLNLPVVSSLM 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 309 GKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHFGLpPRFQKDVKVVQIDICPEEFHQNVKTEVPLL 381
Cdd:PRK07979 243 GLGAFPATHRQSLGMlgmhgtyEANMTMHNADVIFAVGVRFDDRTTNNL-AKYCPNATVLHIDIDPTSISKTVTADIPIV 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 382 GDIGETLA---ELTPRLGD-WTYDESTEWFKKLrenaEKNRAAVEKFVDDHSTPLNYYAAYQPIREfLANNDVIVinega 457
Cdd:PRK07979 322 GDARQVLEqmlELLSQESAhQPLDEIRDWWQQI----EQWRARQCLKYDTHSEKIKPQAVIETLWR-LTKGDAYV----- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 458 nTMDIGRTMM------PSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNL 531
Cdd:PRK07979 392 -TSDVGQHQMfaalyyPFDKPRRWINSGGLGTM----GFGLPAALGVKMALPEETVVCVTGDGSIQMNIQELSTALQYEL 466
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 17531301 532 PVVTVIINNSgiYRGLLPEDDKAIEGDRTLALPVLSLTAECRYEEmckAFGGAGTVVRTVPEIKAALEKAFQK 604
Cdd:PRK07979 467 PVLVLNLNNR--YLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLAE---AYGHVGIQISHPDELESKLSEALEQ 534
|
|
| PRK06112 |
PRK06112 |
acetolactate synthase catalytic subunit; Validated |
68-623 |
1.34e-42 |
|
acetolactate synthase catalytic subunit; Validated
Pssm-ID: 235700 [Multi-domain] Cd Length: 578 Bit Score: 161.85 E-value: 1.34e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 68 DGSNMDGASITAAALKSQGVEYMFGVvGFPVIeVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGIL 147
Cdd:PRK06112 10 FTLNGTVAHAIARALKRHGVEQIFGQ-SLPSA-LFLAAEAIGIRQIAYRTENAGGAMADGYARVSGKVAVVTAQNGPAAT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVD 227
Cdd:PRK06112 88 LLVAPLAEALKASVPIVALVQDVNRDQTDRNAFQELDHIALFQSCTKWVRRVTVAERIDDYVDQAFTAATSGRPGPVVLL 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 228 LPGNLvLTSTEEEISFPPQVPL---PAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSerGAT-QVQQFLTKSKLPW 303
Cdd:PRK06112 168 LPADL-LTAAAAAPAAPRSNSLghfPLDRTVPAPQRLAEAASLLAQAQRPVVVAGGGVHIS--GASaALAALQSLAGLPV 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 304 LATPGGKGVASDLHPRFIG------QARSLA------LREADTVFLIGARFN------WILhfglpprFQKDVKVVQIDI 365
Cdd:PRK06112 245 ATTNMGKGAVDETHPLSLGvvgslmGPRSPGrhlrdlVREADVVLLVGTRTNqngtdsWSL-------YPEQAQYIHIDV 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 366 CPEEFHQNVKTeVPLLGDIGETLAELTPRLG--DWT--YDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPI 441
Cdd:PRK06112 318 DGEEVGRNYEA-LRLVGDARLTLAALTDALRgrDLAarAGRRAALEPAIAAGREAHREDSAPVALSDASPIRPERIMAEL 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 442 REFLANNDVIVINEGANTMDIGRTMMPSRLPKRRLDAGtfGTMGVGHGFSLaaALWARDHSPKTKVLVVQGDSAFGFSAM 521
Cdd:PRK06112 397 QAVLTGDTIVVADASYSSIWVANFLTARRAGMRFLTPR--GLAGLGWGVPM--AIGAKVARPGAPVICLVGDGGFAHVWA 472
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 522 ELETIARYNLPVVTVIINNsGIYrGLLPEDDKAIEGDRTLAlpvlsltaeCRYEE-----MCKAFGGAGTVVRTVPEIKA 596
Cdd:PRK06112 473 ELETARRMGVPVTIVVLNN-GIL-GFQKHAETVKFGTHTDA---------CHFAAvdhaaIARACGCDGVRVEDPAELAQ 541
|
570 580
....*....|....*....|....*..
gi 17531301 597 ALEKAfQKTDGPTVINALisTDSERKP 623
Cdd:PRK06112 542 ALAAA-MAAPGPTLIEVI--TDPSAFP 565
|
|
| TPP_PYR_POX_like |
cd07035 |
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP ... |
79-229 |
1.50e-42 |
|
Pyrimidine (PYR) binding domain of POX and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) and related protiens subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. For glyoxylate carboligase, which belongs to this subfamily, but lacks this conserved glutamate, the rate of the initial TPP activation step is reduced but the ensuing steps of the enzymic reaction proceed efficiently. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. This subfamily includes pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. This subfamily also includes the large catalytic subunit of acetohydroxyacid synthase (AHAS). AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate, a precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. Methanococcus jannaschii sulfopyruvate decarboxylase (MjComDE) and phosphonopyruvate decarboxylase (PpyrDc) also belong to this subfamily. PpyrDc is a homotrimeric enzyme having the PP and PYR domains tandemly arranged on the same subunit. It functions in the biosynthesis of C-P compounds such as bialaphos tripeptide in Streptomyces hygroscopicus. MjComDE is a dodecamer having the PYR and PP domains on different subunits, it has six alpha (PYR/ComD) subunits and six beta (PP/ComE) subunits. MjComDE catalyzes the decarboxylation of sulfopyruvic acid to sulfoacetaldehyde in the coenzyme M pathway.
Pssm-ID: 132918 [Multi-domain] Cd Length: 155 Bit Score: 150.37 E-value: 1.50e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 79 AAALKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATV 158
Cdd:cd07035 4 VEALKAEGVDHVFGVPGGAILPLLDALARSGIRYILVRHEQGAVGMADGYARATGKPGVVLVTSGPGLTNAVTGLANAYL 83
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17531301 159 NCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLP 229
Cdd:cd07035 84 DSIPLLVITGQRPTAGEGRGAFQEIDQVALFRPITKWAYRVTSPEEIPEALRRAFRIALSGRPGPVALDLP 154
|
|
| PRK09107 |
PRK09107 |
acetolactate synthase 3 catalytic subunit; Validated |
67-615 |
1.54e-41 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 236380 [Multi-domain] Cd Length: 595 Bit Score: 159.10 E-value: 1.54e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 67 HDGSNMDGASITAAALKSQGVEYMFGVVGFPVIEVGMAA-QAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPG 145
Cdd:PRK09107 6 HMPRQMTGAEMVVQALKDQGVEHIFGYPGGAVLPIYDEIfQQDDIQHILVRHEQGAGHAAEGYARSTGKPGVVLVTSGPG 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 146 ILHAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVY 225
Cdd:PRK09107 86 ATNAVTPLQDALMDSIPLVCITGQVPTHLIGSDAFQECDTVGITRPCTKHNWLVKDVNDLARVIHEAFHVATSGRPGPVV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 226 VDLPGNLVLTSTeeeISFPPQvPLPAPVSIPP-----IAEIEKAIDTLKSAKKPLVIVGKGAAWSERGATQ-VQQFLTKS 299
Cdd:PRK09107 166 VDIPKDVQFATG---TYTPPQ-KAPVHVSYQPkvkgdAEAITEAVELLANAKRPVIYSGGGVINSGPEASRlLRELVELT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 300 KLPWLATPGGKGV--ASDlhPRFIG--------QArSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEE 369
Cdd:PRK09107 242 GFPITSTLMGLGAypASG--KNWLGmlgmhgtyEA-NMAMHDCDVMLCVGARFDDRIT-GRLDAFSPNSKKIHIDIDPSS 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 370 FHQNVKTEVPLLGDIGETLAELT------------PRLGDWtydesteWFKKLRENAEKNRAavekFVDDHSTPLNYYaA 437
Cdd:PRK09107 318 INKNVRVDVPIIGDVGHVLEDMLrlwkargkkpdkEALADW-------WGQIARWRARNSLA----YTPSDDVIMPQY-A 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 438 YQPIREFLANNDVIVineganTMDIGRTMMPS------RLPKRRLDAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQ 511
Cdd:PRK09107 386 IQRLYELTKGRDTYI------TTEVGQHQMWAaqffgfEEPNRWMTSGGLGTMGYG----LPAALGVQIAHPDALVIDIA 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 512 GDSAFGFSAMELETIARYNLPVVTVIINNSgiYRGLLPEDDKAIEGDR-----TLALPVLSLTAEcryeemckAFGGAGT 586
Cdd:PRK09107 456 GDASIQMCIQEMSTAVQYNLPVKIFILNNQ--YMGMVRQWQQLLHGNRlshsyTEAMPDFVKLAE--------AYGAVGI 525
|
570 580
....*....|....*....|....*....
gi 17531301 587 VVRTVPEIKAALEKAFqKTDGPTVINALI 615
Cdd:PRK09107 526 RCEKPGDLDDAIQEMI-DVDKPVIFDCRV 553
|
|
| PRK07418 |
PRK07418 |
acetolactate synthase large subunit; |
72-618 |
2.07e-41 |
|
acetolactate synthase large subunit;
Pssm-ID: 236014 [Multi-domain] Cd Length: 616 Bit Score: 159.06 E-value: 2.07e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 72 MDGASITAAALKSQGVEYMFGVVG---FPVIEVGMAAQAHG-IKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGIL 147
Cdd:PRK07418 19 ATGAYALMDSLKRHGVKHIFGYPGgaiLPIYDELYKAEAEGwLKHILVRHEQGAAHAADGYARATGKVGVCFGTSGPGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKH---VSRPTSLHTIPAhieKAVRCAMYGRPGAV 224
Cdd:PRK07418 99 NLVTGIATAQMDSVPMVVITGQVPRPAIGTDAFQETDIFGITLPIVKHsyvVRDPSDMARIVA---EAFHIASSGRPGPV 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 225 YVDLPGNLVLTSTEEEISFPPQVPLPA---PVSIPPiAEIEKAIDTLKSAKKPLVIVGKGAAWSerGA-TQVQQFLTKSK 300
Cdd:PRK07418 176 LIDIPKDVGQEEFDYVPVEPGSVKPPGyrpTVKGNP-RQINAALKLIEEAERPLLYVGGGAISA--GAhAELKELAERFQ 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 301 LPWLATPGGKGVASDLHPRFIGQA-------RSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQN 373
Cdd:PRK07418 253 IPVTTTLMGKGAFDEHHPLSVGMLgmhgtayANFAVTECDLLIAVGARFDDRVT-GKLDEFASRAKVIHIDIDPAEVGKN 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 374 VKTEVPLLGDIGETLAELTPRLGDWTYDEST-EWFKKlrenaeknraaVEKFVDDHstPLnyyaaYQPIRE-FLANNDVI 451
Cdd:PRK07418 332 RRPDVPIVGDVRKVLVKLLERSLEPTTPPRTqAWLER-----------INRWKQDY--PL-----VVPPYEgEIYPQEVL 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 452 V-INEGAN----TMDIGRTMMPSRL-----PKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAM 521
Cdd:PRK07418 394 LaVRDLAPdayyTTDVGQHQMWAAQflrngPRRWISSAGLGTM----GFGMPAAMGVKVALPDEEVICIAGDASFLMNIQ 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 522 ELETIARYNLPVVTVIINNSgiYRGLLPEDDKAIEGDRTLALPVlsLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKA 601
Cdd:PRK07418 470 ELGTLAQYGINVKTVIINNG--WQGMVRQWQESFYGERYSASNM--EPGMPDFVKLAEAFGVKGMVISERDQLKDAIAEA 545
|
570
....*....|....*..
gi 17531301 602 FQkTDGPTVINALISTD 618
Cdd:PRK07418 546 LA-HDGPVLIDVHVRRD 561
|
|
| TPP_enzyme_M |
pfam00205 |
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a ... |
261-391 |
2.19e-41 |
|
Thiamine pyrophosphate enzyme, central domain; The central domain of TPP enzymes contains a 2-fold Rossman fold.
Pssm-ID: 425523 [Multi-domain] Cd Length: 137 Bit Score: 146.55 E-value: 2.19e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 261 IEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPGGKGVASDLHPRFIG-------QARSLALREAD 333
Cdd:pfam00205 1 IEKAAELLKKAKRPVILAGGGVRRSG-ASEELRELAEKLGIPVVTTLMGKGAFPEDHPLYLGmlgmhgtPAANEALEEAD 79
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 17531301 334 TVFLIGARFNWILHFGLPPRFQKDVKVVQIDICPEEFHQNVKTEVPLLGDIGETLAEL 391
Cdd:pfam00205 80 LVLAVGARFDDIRTTGKLPEFAPDAKIIHIDIDPAEIGKNYPVDVPIVGDAKETLEAL 137
|
|
| PRK08327 |
PRK08327 |
thiamine pyrophosphate-requiring protein; |
71-607 |
4.47e-40 |
|
thiamine pyrophosphate-requiring protein;
Pssm-ID: 236243 [Multi-domain] Cd Length: 569 Bit Score: 154.77 E-value: 4.47e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 71 NMDGASITAAALKSQGVEYMFGVVG---FPVIEVGMAAQAHGIK---YIGCRNEQAAAYAAqaMGY--LTGKPVALLVVS 142
Cdd:PRK08327 6 MYTAAELFLELLKELGVDYIFINSGtdyPPIIEAKARARAAGRPlpeFVICPHEIVAISMA--HGYalVTGKPQAVMVHV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 143 GPGILHAIGGLANATVNCWPVVCIGG----TADVDLENRGAFQEWSQQ-----ESVRNSCK---HVSRPTSlhtIPAHIE 210
Cdd:PRK08327 84 DVGTANALGGVHNAARSRIPVLVFAGrspyTEEGELGSRNTRIHWTQEmrdqgGLVREYVKwdyEIRRGDQ---IGEVVA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 211 KAVRCAMYGRPGAVYVDLPGNLVLTSTEEEISFPPQVPLPAPVSIPPiAEIEKAIDTLKSAKKPLVIVGKGAAwSERGAT 290
Cdd:PRK08327 161 RAIQIAMSEPKGPVYLTLPREVLAEEVPEVKADAGRQMAPAPPAPDP-EDIARAAEMLAAAERPVIITWRAGR-TAEGFA 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 291 QVQQFLTKSKLPWLATPGGK-GVASDlHPRFIGQARSLALREADTVFLIGARFNWILHFGLPPrfqKDVKVVQIDICPee 369
Cdd:PRK08327 239 SLRRLAEELAIPVVEYAGEVvNYPSD-HPLHLGPDPRADLAEADLVLVVDSDVPWIPKKIRPD---ADARVIQIDVDP-- 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 370 fhqnVKTEVPLLG---------DIGETL----AELTPRLGD---WTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLN 433
Cdd:PRK08327 313 ----LKSRIPLWGfpcdlciqaDTSTALdqleERLKSLASAerrRARRRRAAVRELRIRQEAAKRAEIERLKDRGPITPA 388
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 434 YYAAYqpIREFLANNDVIVINEGANTmdigrTMMPSRLPKRRLDAGTFGtmgvGHGFSLAAALWARDHSPKTKVLVVQGD 513
Cdd:PRK08327 389 YLSYC--LGEVADEYDAIVTEYPFVP-----RQARLNKPGSYFGDGSAG----GLGWALGAALGAKLATPDRLVIATVGD 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 514 SAFGFSAME--LETIARYNLPVVTVIINNSG------IYRGLLPEDDKAIEGDRTLAlpvlSLTAECRYEEMCKAFGGAG 585
Cdd:PRK08327 458 GSFIFGVPEaaHWVAERYGLPVLVVVFNNGGwlavkeAVLEVYPEGYAARKGTFPGT----DFDPRPDFAKIAEAFGGYG 533
|
570 580
....*....|....*....|..
gi 17531301 586 TVVRTVPEIKAALEKAFQKTDG 607
Cdd:PRK08327 534 ERVEDPEELKGALRRALAAVRK 555
|
|
| PRK08199 |
PRK08199 |
thiamine pyrophosphate protein; Validated |
74-618 |
1.08e-38 |
|
thiamine pyrophosphate protein; Validated
Pssm-ID: 181285 [Multi-domain] Cd Length: 557 Bit Score: 150.41 E-value: 1.08e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASITAAALKSQGVEYMFGVVG---FPVIEVgmAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK08199 10 GGQILVDALRANGVERVFCVPGesyLAVLDA--LHDETDIRVIVCRQEGGAAMMAEAYGKLTGRPGICFVTRGPGATNAS 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPG 230
Cdd:PRK08199 88 IGVHTAFQDSTPMILFVGQVARDFREREAFQEIDYRRMFGPMAKWVAEIDDAARIPELVSRAFHVATSGRPGPVVLALPE 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 231 NlVLTSTEEEISFPPQVPLPAPVSIPPIAEIEKAidtLKSAKKPLVIVGkGAAWSERGATQVQQFLTKSKLPWLATPGGK 310
Cdd:PRK08199 168 D-VLSETAEVPDAPPYRRVAAAPGAADLARLAEL---LARAERPLVILG-GSGWTEAAVADLRAFAERWGLPVACAFRRQ 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 311 GVASDLHPRFIGQ-----ARSLA--LREADTVFLIGARFNWILHFGL----PPRFQKdvKVVQIDICPEEFHQNVKTEVP 379
Cdd:PRK08199 243 DLFDNRHPNYAGDlglgiNPALAarIREADLVLAVGTRLGEVTTQGYtlldIPVPRQ--TLVHVHPDAEELGRVYRPDLA 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 380 LLGDIGETLAeltpRLGDWTYDESTEWfkklRENAEKNRAAVEKFVDDHSTP--LNYYAAYQPIREFLaNNDVIVINEGA 457
Cdd:PRK08199 321 IVADPAAFAA----ALAALEPPASPAW----AEWTAAAHADYLAWSAPLPGPgaVQLGEVMAWLRERL-PADAIITNGAG 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 458 NTMDIGRTMMPSRLPKRRLdAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVI 537
Cdd:PRK08199 392 NYATWLHRFFRFRRYRTQL-APTSGSMGYG----LPAAIAAKLLFPERTVVAFAGDGCFLMNGQELATAVQYGLPIIVIV 466
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 538 INNsGIYRGLLPEDDKAIEGdRTLAlpvLSLTaECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKTdGPTVINALIST 617
Cdd:PRK08199 467 VNN-GMYGTIRMHQEREYPG-RVSG---TDLT-NPDFAALARAYGGHGETVERTEDFAPAFERALASG-KPALIEIRIDP 539
|
.
gi 17531301 618 D 618
Cdd:PRK08199 540 E 540
|
|
| sulphoacet_xsc |
TIGR03457 |
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde ... |
82-611 |
5.25e-38 |
|
sulfoacetaldehyde acetyltransferase; Members of this protein family are sulfoacetaldehyde acetyltransferase, an enzyme of taurine utilization. Taurine, or 2-aminoethanesulfonate, can be used by bacteria as a source of carbon, nitrogen, and sulfur. [Central intermediary metabolism, Other]
Pssm-ID: 132497 [Multi-domain] Cd Length: 579 Bit Score: 148.86 E-value: 5.25e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVGFPVIEVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATVNCW 161
Cdd:TIGR03457 12 LVANGVTHAFGIMGSAFMDAMDLFPPAGIRFIPVVHEQGAGHMADGFARVTGRMSMVIGQNGPGVTNCVTAIAAAYWAHT 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 162 PVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRpGAVYVDLPGNLVLTSTEEEI 241
Cdd:TIGR03457 92 PVVIVTPEAGTKTIGLGGFQEADQLPMFQEFTKYQGHVRHPSRMAEVLNRCFERAWREM-GPAQLNIPRDYFYGEIDVEI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 242 sfppqvPLPAPVSIPP--IAEIEKAIDTLKSAKKPLVIVGKGA----------AWSER-GATQVQQFLTKSKLP-----W 303
Cdd:TIGR03457 171 ------PRPVRLDRGAggATSLAQAARLLAEAKFPVIISGGGVvmgdaveeckALAERlGAPVVNSYLHNDSFPashplW 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 304 LATPGGKGVASDLHprfigqarslALREADTVFLIGARFNwilHFGLPPR-----FQKDVKVVQIDICPEEFHQNVKTEV 378
Cdd:TIGR03457 245 VGPLGYQGSKAAMK----------LISDADVVLALGTRLG---PFGTLPQygidyWPKNAKIIQVDANAKMIGLVKKVTV 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 379 PLLGDIGETLAELTPRL----GDWTYDESTE--------WFKKLRENA-EKNRAAVEKFVDDHSTPLNYYAAYQPIREF- 444
Cdd:TIGR03457 312 GICGDAKAAAAEILQRLagkaGDANRAERKAkiqaersaWEQELSEMThERDPFSLDMIVEQRQEEGNWLHPRQVLRELe 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 445 -LANNDVIVINEGANTMDIGRTMMPSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMEL 523
Cdd:TIGR03457 392 kAMPEDAIVSTDIGNINSVANSYLRFEKPRKFLAPMSFGNC----GYAFPTIIGAKIAAPDRPVVAYAGDGAWGMSMNEI 467
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 524 ETIARYNLPVVTVIINNsgiyRGLLPEDDKAIE--GDRTLAlpvLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKA 601
Cdd:TIGR03457 468 MTAVRHDIPVTAVVFRN----RQWGAEKKNQVDfyNNRFVG---TELESELSFAGIADAMGAKGVVVDKPEDVGPALKKA 540
|
570
....*....|.
gi 17531301 602 FQ-KTDGPTVI 611
Cdd:TIGR03457 541 IAaQAEGKTTV 551
|
|
| PRK06965 |
PRK06965 |
acetolactate synthase 3 catalytic subunit; Validated |
57-606 |
7.69e-38 |
|
acetolactate synthase 3 catalytic subunit; Validated
Pssm-ID: 180780 [Multi-domain] Cd Length: 587 Bit Score: 148.41 E-value: 7.69e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 57 SRINSRKLRNHDGSNMDGASITAAALKSQGVEYMFGVVGFPVIEVGMAA-QAHGIKYIGCRNEQAAAYAAQAMGYLTGKP 135
Cdd:PRK06965 6 AEFSTAESLSPPAADSIGAEILMKALAAEGVEFIWGYPGGAVLYIYDELyKQDKIQHVLVRHEQAAVHAADGYARATGKV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 136 VALLVVSGPGILHAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRC 215
Cdd:PRK06965 86 GVALVTSGPGVTNAVTGIATAYMDSIPMVVISGQVPTAAIGQDAFQECDTVGITRPIVKHNFLVKDVRDLAETVKKAFYI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 216 AMYGRPGAVYVDLPGNLVLTSTEEEisFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQ 293
Cdd:PRK06965 166 ARTGRPGPVVVDIPKDVSKTPCEYE--YPKSVEMRSynPVTKGHSGQIRKAVSLLLSAKRPYIYTGGGVILAN-ASRELR 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 294 QFLTKSKLPWLATPGGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILhFGLPPRF-QKDVKVVQIDI 365
Cdd:PRK06965 243 QLADLLGYPVTNTLMGLGAYPASDKKFLGMlgmhgtyEANMAMQHCDVLIAIGARFDDRV-IGNPAHFaSRPRKIIHIDI 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 366 CPEEFHQNVKTEVPLLGDIGETLAEL------------TPRLGDWtYDESTEWFK----KLRENAE--KNRAAVEKFVDd 427
Cdd:PRK06965 322 DPSSISKRVKVDIPIVGDVKEVLKELieqlqtaehgpdADALAQW-WKQIEGWRSrdclKYDRESEiiKPQYVVEKLWE- 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 428 hstplnyyaayqpirefLANNDVIVineganTMDIGRTMMPSRL------PKRRLDAGTFGTMGVGhgfsLAAALWARDH 501
Cdd:PRK06965 400 -----------------LTDGDAFV------CSDVGQHQMWAAQfyrfnePRRWINSGGLGTMGVG----LPYAMGIKMA 452
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 502 SPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNSgiYRGLLP-----EDDKAIEGDRTLALPVLSLTAEcryee 576
Cdd:PRK06965 453 HPDDDVVCITGEGSIQMCIQELSTCLQYDTPVKIISLNNR--YLGMVRqwqeiEYSKRYSHSYMDALPDFVKLAE----- 525
|
570 580 590
....*....|....*....|....*....|
gi 17531301 577 mckAFGGAGTVVRTVPEIKAALEKAFQKTD 606
Cdd:PRK06965 526 ---AYGHVGMRIEKTSDVEPALREALRLKD 552
|
|
| PDC1 |
COG3961 |
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate ... |
82-618 |
2.52e-36 |
|
TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase [Carbohydrate transport and metabolism, Coenzyme transport and metabolism, General function prediction only]; TPP-dependent 2-oxoacid decarboxylase, includes indolepyruvate decarboxylase is part of the Pathway/BioSystem: Pyruvate oxidation
Pssm-ID: 443161 [Multi-domain] Cd Length: 545 Bit Score: 143.38 E-value: 2.52e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVG---FPVIEvgmAAQAH-GIKYIGCRNEqaaayaaqamgyLTG----------KPVALLVVS-GPGI 146
Cdd:COG3961 15 LAELGIRHIFGVPGdynLPFLD---AIEAHpGIRWVGCCNE------------LNAgyaadgyarvNGLGALVTTyGVGE 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 147 LHAIGGLANATVNCWPVVCIGGTADVDLENRGA----------FQewSQQESVRN-SCKHVS-RPtslHTIPAHIEKAVR 214
Cdd:COG3961 80 LSAINGIAGAYAERVPVVHIVGAPGTRAQRRGPllhhtlgdgdFD--HFLRMFEEvTVAQAVlTP---ENAAAEIDRVLA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 215 CA-MYGRPgaVYVDLPGNLVltstEEEISFPPQV-PLPAPVSIPPIAE--IEKAIDTLKSAKKPLVIVGKGAAwsERGAT 290
Cdd:COG3961 155 AAlREKRP--VYIELPRDVA----DAPIEPPEAPlPLPPPASDPAALAaaVAAAAERLAKAKRPVILAGVEVH--RFGLQ 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 291 -QVQQFLTKSKLPWLATPGGKGVASDLHPRFIG----QARSLALRE----ADTVFLIGARFN----WILHFGLPPRFqkd 357
Cdd:COG3961 227 eELLALAEKTGIPVATTLLGKSVLDESHPQFIGtyagAASSPEVREyvenADCVLCLGVVFTdtntGGFTAQLDPER--- 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 358 vkvvQIDICPEEFH--QNVKTEVPLlgdiGETLAELTPRLgdwtydestewfKKLRENAEKNRAAVEKFVDDHSTPLNYY 435
Cdd:COG3961 304 ----TIDIQPDSVRvgGHIYPGVSL----ADFLEALAELL------------KKRSAPLPAPAPPPPPPPAAPDAPLTQD 363
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 436 AAYQPIREFLANNDVIVInegantmDIGRTMMPS---RLPKrrlDAGTFGTMGVGH-GFSLAAALWARDHSPKTKVLVVQ 511
Cdd:COG3961 364 RLWQRLQAFLDPGDIVVA-------DTGTSLFGAadlRLPE---GATFIAQPLWGSiGYTLPAALGAALAAPDRRVILLV 433
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 512 GDSAFGFSAMELETIARYNLPVVTVIINNSG--IYRGLLPED----DkaIegdrtlalpvlsltAECRYEEMCKAFGGA- 584
Cdd:COG3961 434 GDGAFQLTAQELSTMLRYGLKPIIFVLNNDGytIERAIHGPDgpynD--I--------------ANWDYAKLPEAFGGGn 497
|
570 580 590
....*....|....*....|....*....|....*.
gi 17531301 585 --GTVVRTVPEIKAALEKAFQKTDGPTVINALISTD 618
Cdd:COG3961 498 alGFRVTTEGELEEALAAAEANTDRLTLIEVVLDKM 533
|
|
| ilvB |
CHL00099 |
acetohydroxyacid synthase large subunit |
82-618 |
4.47e-36 |
|
acetohydroxyacid synthase large subunit
Pssm-ID: 214363 [Multi-domain] Cd Length: 585 Bit Score: 143.30 E-value: 4.47e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVG---FPVIEVGMAAQAHG-IKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANAT 157
Cdd:CHL00099 20 LVRHGVKHIFGYPGgaiLPIYDELYAWEKKGlIKHILVRHEQGAAHAADGYARSTGKVGVCFATSGPGATNLVTGIATAQ 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 158 VNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKH---VSRPTSLHTIpahIEKAVRCAMYGRPGAVYVDLPGNLVL 234
Cdd:CHL00099 100 MDSVPLLVITGQVGRAFIGTDAFQEVDIFGITLPIVKHsyvVRDARDISRI---VAEAFYIAKHGRPGPVLIDIPKDVGL 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 235 tsteEEISFPPQVPLPAPVSIP--------PIAEIEKAIDTLKSAKKPLVIVGKGAAWSerGATQ-VQQFLTKSKLPWLA 305
Cdd:CHL00099 177 ----EKFDYYPPEPGNTIIKILgcrpiykpTIKRIEQAAKLILQSSQPLLYVGGGAIIS--DAHQeITELAELYKIPVTT 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 306 TPGGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTEV 378
Cdd:CHL00099 251 TLMGKGIFDEDHPLCLGMlgmhgtaYANFAVSECDLLIALGARFDDRVT-GKLDEFACNAQVIHIDIDPAEIGKNRIPQV 329
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 379 PLLGDIGETLAEL---TPRLGDWTYDESTE-WFKKLRENAEKNRAAVEKfvddhstPLNYYAAYQPIREF--LANNDVIv 452
Cdd:CHL00099 330 AIVGDVKKVLQELlelLKNSPNLLESEQTQaWRERINRWRKEYPLLIPK-------PSTSLSPQEVINEIsqLAPDAYF- 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 453 ineganTMDIGRTMMPSR-----LPKRRLDAGTFGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIA 527
Cdd:CHL00099 402 ------TTDVGQHQMWAAqflkcKPRKWLSSAGLGTMGYG----LPAAIGAQIAHPNELVICISGDASFQMNLQELGTIA 471
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 528 RYNLPVVTVIINNSgiYRGLLPEDDKAIEGDR------TLALPVLSLTAEcryeemckAFGGAGTVVRTVPEIKAALEKA 601
Cdd:CHL00099 472 QYNLPIKIIIINNK--WQGMVRQWQQAFYGERyshsnmEEGAPDFVKLAE--------AYGIKGLRIKSRKDLKSSLKEA 541
|
570
....*....|....*..
gi 17531301 602 FqKTDGPTVINALISTD 618
Cdd:CHL00099 542 L-DYDGPVLIDCQVIED 557
|
|
| PLN02470 |
PLN02470 |
acetolactate synthase |
74-615 |
4.67e-35 |
|
acetolactate synthase
Pssm-ID: 215261 [Multi-domain] Cd Length: 585 Bit Score: 140.26 E-value: 4.67e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASITAAALKSQGVEYMFGVVGFPVIEVGMA-AQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGG 152
Cdd:PLN02470 15 GADILVEALEREGVDTVFAYPGGASMEIHQAlTRSNCIRNVLCRHEQGEVFAAEGYAKASGKVGVCIATSGPGATNLVTG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 153 LANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGNL 232
Cdd:PLN02470 95 LADALLDSVPLVAITGQVPRRMIGTDAFQETPIVEVTRSITKHNYLVMDVEDIPRVIREAFFLASSGRPGPVLVDIPKDI 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 233 vltstEEEISFP---PQVPLPAPVS----IPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSergATQVQQFLTKSKLPWLA 305
Cdd:PLN02470 175 -----QQQLAVPnwnQPMKLPGYLSrlpkPPEKSQLEQIVRLISESKRPVVYVGGGCLNS---SEELREFVELTGIPVAS 246
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 306 TPGGKGV--ASD-LHPRFIGQ----ARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDICPEEFHQNVKTEV 378
Cdd:PLN02470 247 TLMGLGAfpASDeLSLQMLGMhgtvYANYAVDSADLLLAFGVRFDDRVT-GKLEAFASRASIVHIDIDPAEIGKNKQPHV 325
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 379 PLLGDIGETLAELTPRL---GDWTYDEStEWFKKLRENAEKNRAAVEKFVDdhSTPLNYyaAYQPIREFLANNDVIVINE 455
Cdd:PLN02470 326 SVCADVKLALQGLNKLLeerKAKRPDFS-AWRAELDEQKEKFPLSYPTFGD--AIPPQY--AIQVLDELTDGNAIISTGV 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 456 GANTMDIGRtMMPSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVT 535
Cdd:PLN02470 401 GQHQMWAAQ-WYKYKEPRRWLTSGGLGAM----GFGLPAAIGAAAANPDAIVVDIDGDGSFIMNIQELATIHVENLPVKI 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 536 VIINNSGIYRGLLPEDD--KAIEGDRTLALPvlSLTAECrYEEMCK---AFGGAGTVVRTVPEIKAALEKAFQkTDGPTV 610
Cdd:PLN02470 476 MVLNNQHLGMVVQWEDRfyKANRAHTYLGDP--DAEAEI-FPDFLKfaeGCKIPAARVTRKSDLREAIQKMLD-TPGPYL 551
|
....*
gi 17531301 611 INALI 615
Cdd:PLN02470 552 LDVIV 556
|
|
| PRK09124 |
PRK09124 |
ubiquinone-dependent pyruvate dehydrogenase; |
75-618 |
2.92e-34 |
|
ubiquinone-dependent pyruvate dehydrogenase;
Pssm-ID: 181661 [Multi-domain] Cd Length: 574 Bit Score: 137.81 E-value: 2.92e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 75 ASITAAALKSQGVEYMFGVVGFPVIEVGMAAQAHG-IKYIGCRNEQAAAYAAQAMGYLTGKpvaLLVVS---GPGILHAI 150
Cdd:PRK09124 6 ADYIAKTLEQAGVKRIWGVTGDSLNGLSDSLRRMGtIEWMHTRHEEVAAFAAGAEAQLTGE---LAVCAgscGPGNLHLI 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGG---TADVDLenrGAFQEWSQQESVRnSCKH----VSRPtslHTIPAHIEKAVRCAMYGRPGA 223
Cdd:PRK09124 83 NGLFDCHRNHVPVLAIAAhipSSEIGS---GYFQETHPQELFR-ECSHycelVSNP---EQLPRVLAIAMRKAILNRGVA 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 224 VYVdLPGNLVLTSTEEEISFPPQVPlPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAwserGA-TQVQQFLTKSKLP 302
Cdd:PRK09124 156 VVV-LPGDVALKPAPERATPHWYHA-PQPVVTPAEEELRKLAALLNGSSNITLLCGSGCA----GAhDELVALAETLKAP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 303 WLATPGGK-----------------GVASDLHprfigqarslALREADTVFLIGARFnwilhfglPPR--FQKDVKVVQI 363
Cdd:PRK09124 230 IVHALRGKehveydnpydvgmtgliGFSSGYH----------AMMNCDTLLMLGTDF--------PYRqfYPTDAKIIQI 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 364 DICPEEFHQNVKTEVPLLGDIGETLAELTPRLgdwTYDESTEWFKKLRENAEKNRaaveKFVDDHSTPlnyYAAYQPIR- 442
Cdd:PRK09124 292 DINPGSLGRRSPVDLGLVGDVKATLAALLPLL---EEKTDRKFLDKALEHYRKAR----KGLDDLAVP---SDGGKPIHp 361
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 443 EFLANndviVINEGAN-----TMDIGR-TMMPSRL----PKRRLdAGTF--GTMGVghgfSLAAALWARDHSPKTKVLVV 510
Cdd:PRK09124 362 QYLAR----QISEFAAddaifTCDVGTpTVWAARYlkmnGKRRL-LGSFnhGSMAN----AMPQALGAQAAHPGRQVVAL 432
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 511 QGDSafGFSAM--ELETIARYNLPVVTVIINNSGIyrGLLPEDDKA---IEGDRTLALPVlsltaecrYEEMCKAFGGAG 585
Cdd:PRK09124 433 SGDG--GFSMLmgDFLSLVQLKLPVKIVVFNNSVL--GFVAMEMKAggyLTDGTDLHNPD--------FAAIAEACGITG 500
|
570 580 590
....*....|....*....|....*....|...
gi 17531301 586 TVVRTVPEIKAALEKAFQkTDGPTVINALISTD 618
Cdd:PRK09124 501 IRVEKASELDGALQRAFA-HDGPALVDVVTAKQ 532
|
|
| PRK07525 |
PRK07525 |
sulfoacetaldehyde acetyltransferase; Validated |
82-617 |
3.45e-34 |
|
sulfoacetaldehyde acetyltransferase; Validated
Pssm-ID: 236042 [Multi-domain] Cd Length: 588 Bit Score: 137.44 E-value: 3.45e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVG---FPVIEVGMAAqahGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATV 158
Cdd:PRK07525 16 LQAHGITHAFGIIGsafMDASDLFPPA---GIRFIDVAHEQNAGHMADGYTRVTGRMGMVIGQNGPGITNFVTAVATAYW 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 159 NCWPVVCI---GGTADVDLenrGAFQEWSQ----------QESVRnsckHVSRptslhtIPAHIEKAVRCAMYGRpGAVY 225
Cdd:PRK07525 93 AHTPVVLVtpqAGTKTIGQ---GGFQEAEQmpmfedmtkyQEEVR----DPSR------MAEVLNRVFDKAKRES-GPAQ 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 226 VDLPGNLVLTSTEEEISFPPQVPLPApvsiPPIAEIEKAIDTLKSAKKPLVIVGKG----------AAWSER-GATQVQQ 294
Cdd:PRK07525 159 INIPRDYFYGVIDVEIPQPVRLERGA----GGEQSLAEAAELLSEAKFPVILSGAGvvlsdaieecKALAERlDAPVACG 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 295 FLTKSKLPwlatpggkgvASdlHPRFIG-------QARSLALREADTVFLIGARFNwilHFGLPPR-----FQKDVKVVQ 362
Cdd:PRK07525 235 YLHNDAFP----------GS--HPLWVGplgyngsKAAMELIAKADVVLALGTRLN---PFGTLPQygidyWPKDAKIIQ 299
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 363 IDICPEEFHQNVKTEVPLLGDIGETLAELTPRL-----GDWTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYA- 436
Cdd:PRK07525 300 VDINPDRIGLTKKVSVGICGDAKAVARELLARLaerlaGDAGREERKALIAAEKSAWEQELSSWDHEDDDPGTDWNEEAr 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 437 -----------AYQPIREFLAnNDVIVINEGANTMDIGRTMMPSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKT 505
Cdd:PRK07525 380 arkpdymhprqALREIQKALP-EDAIVSTDIGNNCSIANSYLRFEKGRKYLAPGSFGNC----GYAFPAIIGAKIACPDR 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 506 KVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNsgiyRGLLPE--------DDKAIEGDrtlalpvlsLTAECRYEEM 577
Cdd:PRK07525 455 PVVGFAGDGAWGISMNEVMTAVRHNWPVTAVVFRN----YQWGAEkknqvdfyNNRFVGTE---------LDNNVSYAGI 521
|
570 580 590 600
....*....|....*....|....*....|....*....|..
gi 17531301 578 CKAFGGAGTVVRTVPEIKAALEKAF--QKTDGPTVINALIST 617
Cdd:PRK07525 522 AEAMGAEGVVVDTQEELGPALKRAIdaQNEGKTTVIEIMCNQ 563
|
|
| PRK07789 |
PRK07789 |
acetolactate synthase 1 catalytic subunit; Validated |
62-619 |
3.48e-34 |
|
acetolactate synthase 1 catalytic subunit; Validated
Pssm-ID: 236098 [Multi-domain] Cd Length: 612 Bit Score: 137.81 E-value: 3.48e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 62 RKLRNHDGSNMDGASITAAALKSQGVEYMFGVVG---FPVIEVGMAAQAhgIKYIGCRNEQAAAYAAQAMGYLTGKPVAL 138
Cdd:PRK07789 21 ARPRIVAPERMTGAQAVVRSLEELGVDVVFGIPGgaiLPVYDPLFDSTK--VRHVLVRHEQGAGHAAEGYAQATGRVGVC 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 139 LVVSGPGILHAIGGLANATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKH---VSRPTSlhtIPAHIEKAVRC 215
Cdd:PRK07789 99 MATSGPGATNLVTPIADANMDSVPVVAITGQVGRGLIGTDAFQEADIVGITMPITKHnflVTDADD---IPRVIAEAFHI 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 216 AMYGRPGAVYVDLPGNlVLTStEEEISFPPQVPLPA--PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSERGAtQVQ 293
Cdd:PRK07789 176 ASTGRPGPVLVDIPKD-ALQA-QTTFSWPPRMDLPGyrPVTKPHGKQIREAAKLIAAARRPVLYVGGGVIRAEASA-ELR 252
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 294 QFLTKSKLPWLATPGGKGVASDLHPRFIGQ-------ARSLALREADTVFLIGARFNWILHfGLPPRFQKDVKVVQIDIC 366
Cdd:PRK07789 253 ELAELTGIPVVTTLMARGAFPDSHPQHLGMpgmhgtvAAVAALQRSDLLIALGARFDDRVT-GKLDSFAPDAKVIHADID 331
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 367 PEEFHQNVKTEVPLLGDIGETLAELTPRLGDWT----YDESTEWFKKLRENAEKNRAAVEKFVDDHSTPlnyyaayQPIR 442
Cdd:PRK07789 332 PAEIGKNRHADVPIVGDVKEVIAELIAALRAEHaaggKPDLTAWWAYLDGWRETYPLGYDEPSDGSLAP-------QYVI 404
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 443 EFL---ANNDVI-VINEGANTMDIGRTMMPSRlPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGF 518
Cdd:PRK07789 405 ERLgeiAGPDAIyVAGVGQHQMWAAQFIDYEK-PRTWLNSGGLGTM----GYAVPAAMGAKVGRPDKEVWAIDGDGCFQM 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 519 SAMELETIARYNLPVVTVIINNSGI----------YRGLLPEDDKAIEGDRtlaLPVLSLTAEcryeemckAFGGAGTVV 588
Cdd:PRK07789 480 TNQELATCAIEGIPIKVALINNGNLgmvrqwqtlfYEERYSNTDLHTHSHR---IPDFVKLAE--------AYGCVGLRC 548
|
570 580 590
....*....|....*....|....*....|.
gi 17531301 589 RTVPEIKAALEKAFQKTDGPTVINALISTDS 619
Cdd:PRK07789 549 EREEDVDAVIEKARAINDRPVVIDFVVGKDA 579
|
|
| PRK06546 |
PRK06546 |
pyruvate dehydrogenase; Provisional |
82-614 |
1.64e-31 |
|
pyruvate dehydrogenase; Provisional
Pssm-ID: 180614 [Multi-domain] Cd Length: 578 Bit Score: 129.34 E-value: 1.64e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVG---FPVieVGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATV 158
Cdd:PRK06546 13 LVAAGVKRIYGIVGdslNPI--VDAVRRTGGIEWVHVRHEEAAAFAAAAEAQLTGKLAVCAGSCGPGNLHLINGLYDAHR 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 159 NCWPVVCIGG---TADVDLenrGAFQEwSQQESVRNSCKH----VSRPTSLhtiPAHIEKAVRCAMyGRPGAVYVDLPGN 231
Cdd:PRK06546 91 SGAPVLAIAShipSAQIGS---GFFQE-THPDRLFVECSGycemVSSAEQA---PRVLHSAIQHAV-AGGGVSVVTLPGD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 232 LvlTSTEEEISFPPQVPLPA-PVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAawseRGA-TQVQQFLTKSKLPWLATPGG 309
Cdd:PRK06546 163 I--ADEPAPEGFAPSVISPRrPTVVPDPAEVRALADAINEAKKVTLFAGAGV----RGAhAEVLALAEKIKAPVGHSLRG 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 310 KGVASDLHPRFIGQARSL-------ALREADTVFLIGARFNWilhfglpPRFQKDVKVVQIDICPEEFHQNVKTEVPLLG 382
Cdd:PRK06546 237 KEWIQYDNPFDVGMSGLLgygaaheAMHEADLLILLGTDFPY-------DQFLPDVRTAQVDIDPEHLGRRTRVDLAVHG 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 383 DIGETLAELTPRLGDWTyDEStewF--KKLRENAEKNRAAVEKFVDD--HSTPLN-YYAAYQpIREFLANNDVIVINEGA 457
Cdd:PRK06546 310 DVAETIRALLPLVKEKT-DRR---FldRMLKKHARKLEKVVGAYTRKveKHTPIHpEYVASI-LDELAADDAVFTVDTGM 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 458 NTMDIGRTMMPsrLPKRRLdAGTF--GTMGVghgfSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVT 535
Cdd:PRK06546 385 CNVWAARYITP--NGRRRV-IGSFrhGSMAN----ALPHAIGAQLADPGRQVISMSGDGGLSMLLGELLTVKLYDLPVKV 457
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 536 VIINNSGIyrGLLpEDDKAIEGdrtlaLPVLSLT-AECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFqKTDGPTVI--- 611
Cdd:PRK06546 458 VVFNNSTL--GMV-KLEMLVDG-----LPDFGTDhPPVDYAAIAAALGIHAVRVEDPKDVRGALREAF-AHPGPALVdvv 528
|
....*.
gi 17531301 612 ---NAL 614
Cdd:PRK06546 529 tdpNAL 534
|
|
| PRK07524 |
PRK07524 |
5-guanidino-2-oxopentanoate decarboxylase; |
82-611 |
3.05e-29 |
|
5-guanidino-2-oxopentanoate decarboxylase;
Pssm-ID: 236041 [Multi-domain] Cd Length: 535 Bit Score: 122.39 E-value: 3.05e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVGFPVIEV--GMAAQahGIKYIGCRNEqaaaYAAQAM--GY--LTGKPVALLVVSGPGILHAIGGLAN 155
Cdd:PRK07524 12 LEAYGVETVFGIPGVHTVELyrGLAGS--GIRHVTPRHE----QGAGFMadGYarVSGKPGVCFIITGPGMTNIATAMGQ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 156 ATVNCWPVVCIGGTADVDL--ENRGAFQEW-SQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVDLPGNL 232
Cdd:PRK07524 86 AYADSIPMLVISSVNRRASlgKGRGKLHELpDQRAMVAGVAAFSHTLMSAEDLPEVLARAFAVFDSARPRPVHIEIPLDV 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 233 VLTSTEEEISFPPQVPLPAPvsiPPIAEIEKAIDTLKSAKKPLVIVGKGAAwseRGATQVQQFLTKSKLPWLATPGGKGV 312
Cdd:PRK07524 166 LAAPADHLLPAPPTRPARPG---PAPAALAQAAERLAAARRPLILAGGGAL---AAAAALRALAERLDAPVALTINAKGL 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 313 ASDLHPRFIGQARSLA-----LREADTVFLIG---ARFNWILHF-GlppRFQKDVKVVQIDICPEEFHQNVKTEVPLLGD 383
Cdd:PRK07524 240 LPAGHPLLLGASQSLPavralIAEADVVLAVGtelGETDYDVYFdG---GFPLPGELIRIDIDPDQLARNYPPALALVGD 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 384 IGETLAELTPRLGDwtyDESTEWFKKLRenAEKNRAAVEKFVDDhstplnYYAAYQPIREFLANN--DVIVINEGANTMD 461
Cdd:PRK07524 317 ARAALEALLARLPG---QAAAADWGAAR--VAALRQALRAEWDP------LTAAQVALLDTILAAlpDAIFVGDSTQPVY 385
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 462 IGRTMMPSRLPKRRLDAGT-FGTMGVGhgfsLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINN 540
Cdd:PRK07524 386 AGNLYFDADAPRRWFNASTgYGTLGYG----LPAAIGAALGAPERPVVCLVGDGGLQFTLPELASAVEADLPLIVLLWNN 461
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17531301 541 SG---IYRGLLpedDKAIEgdrtlalPVLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVI 611
Cdd:PRK07524 462 DGygeIRRYMV---ARDIE-------PVGVDPYTPDFIALARAFGCAAERVADLEQLQAALRAAFA-RPGPTLI 524
|
|
| PRK07064 |
PRK07064 |
thiamine pyrophosphate-binding protein; |
74-611 |
7.83e-29 |
|
thiamine pyrophosphate-binding protein;
Pssm-ID: 180820 [Multi-domain] Cd Length: 544 Bit Score: 121.25 E-value: 7.83e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 74 GASItAAALKSQGVEYMFGVVG---FPVIEvGMAAQAHgIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAI 150
Cdd:PRK07064 6 GELI-AAFLEQCGVKTAFGVISihnMPILD-AIGRRGK-IRFVPARGEAGAVNMADAHARVSGGLGVALTSTGTGAGNAA 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 151 GGLANATVNCWPVVCIGGTADVDL--ENRGAFQEWSQQESVRNSC-KHVSRPTSLHTIPAHIEKAVRCAMYGRPGAVYVD 227
Cdd:PRK07064 83 GALVEALTAGTPLLHITGQIETPYldQDLGYIHEAPDQLTMLRAVsKAAFRVRSAETALATIREAVRVALTAPTGPVSVE 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 228 LPGNLVLTsteeEISFP-PQVPLPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAawseRGATQVQQFLTKSKLPWLAT 306
Cdd:PRK07064 163 IPIDIQAA----EIELPdDLAPVHVAVPEPDAAAVAELAERLAAARRPLLWLGGGA----RHAGAEVKRLVDLGFGVVTS 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 307 PGGKGVASDLHPRFIG----QARSLAL-READTVFLIGARF--NWILHFGLP-PRfqkdvKVVQIDICPEEFHQNVKTEV 378
Cdd:PRK07064 235 TQGRGVVPEDHPASLGafnnSAAVEALyKTCDLLLVVGSRLrgNETLKYSLAlPR-----PLIRVDADAAADGRGYPNDL 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 379 PLLGDIGETLAELTPRLGDwTYDESTEWFKKLRENAEKNRAAVEKFVDDHSTPLNYYAAYQPiREFLANNDVIVINEgan 458
Cdd:PRK07064 310 FVHGDAARVLARLADRLEG-RLSVDPAFAADLRAAREAAVADLRKGLGPYAKLVDALRAALP-RDGNWVRDVTISNS--- 384
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 459 tmDIGRTMMPSRLPKrrldAGTFGTMGvGHGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVII 538
Cdd:PRK07064 385 --TWGNRLLPIFEPR----ANVHALGG-GIGQGLAMAIGAALAGPGRKTVGLVGDGGLMLNLGELATAVQENANMVIVLM 457
|
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17531301 539 NNS--GIYRGLlpeDDKAIEGDR---TLALPvlsltaecRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQKtDGPTVI 611
Cdd:PRK07064 458 NDGgyGVIRNI---QDAQYGGRRyyvELHTP--------DFALLAASLGLPHWRVTSADDFEAVLREALAK-EGPVLV 523
|
|
| TPP_enzyme_C |
pfam02775 |
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain; |
456-613 |
1.82e-27 |
|
Thiamine pyrophosphate enzyme, C-terminal TPP binding domain;
Pssm-ID: 460689 [Multi-domain] Cd Length: 151 Bit Score: 108.06 E-value: 1.82e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 456 GANTMDIGRtMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALwARdhsPKTKVLVVQGDSAFGFSAMELETIARYNLPVVT 535
Cdd:pfam02775 3 GCHQMWAAQ-YYRFRPPRRYLTSGGLGTMGYGLPAAIGAKL-AR---PDRPVVAIAGDGGFQMNLQELATAVRYNLPITV 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 536 VIINNS--GIYRGLLpeddkAIEGDRTLALPVLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFqKTDGPTVINA 613
Cdd:pfam02775 78 VVLNNGgyGMTRGQQ-----TPFGGGRYSGPSGKILPPVDFAKLAEAYGAKGARVESPEELEEALKEAL-EHDGPALIDV 151
|
|
| TPP_enzymes |
cd00568 |
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic ... |
445-615 |
4.28e-25 |
|
Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and the branched chain alpha-keto acid dehydrogenase complexes.
Pssm-ID: 238318 [Multi-domain] Cd Length: 168 Bit Score: 101.95 E-value: 4.28e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 445 LANNDVIVINEGANTMDIGRTMMPSRLPKRRLDAGTFGTMGvghgFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELE 524
Cdd:cd00568 9 ALPEDAIVVNDAGNSAYWAYRYLPLRRGRRFLTSTGFGAMG----YGLPAAIGAALAAPDRPVVCIAGDGGFMMTGQELA 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 525 TIARYNLPVVTVIINNsGIYrGLLpeddKAIEGDRTLALPVLSLTAECRYEEMCKAFGGAGTVVRTVPEIKAALEKAFQk 604
Cdd:cd00568 85 TAVRYGLPVIVVVFNN-GGY-GTI----RMHQEAFYGGRVSGTDLSNPDFAALAEAYGAKGVRVEDPEDLEAALAEALA- 157
|
170
....*....|.
gi 17531301 605 TDGPTVINALI 615
Cdd:cd00568 158 AGGPALIEVKT 168
|
|
| PRK11269 |
PRK11269 |
glyoxylate carboligase; Provisional |
82-548 |
8.61e-24 |
|
glyoxylate carboligase; Provisional
Pssm-ID: 183066 [Multi-domain] Cd Length: 591 Bit Score: 105.83 E-value: 8.61e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVGFPVIEVGMAAQAHG-IKYIGCRNEQAAAYAAQamGYLTGKPVALLV---VSGPGILHAIGGLANAT 157
Cdd:PRK11269 14 LEKEGVTTAFGVPGAAINPFYSAMRKHGgIRHILARHVEGASHMAE--GYTRATAGNIGVcigTSGPAGTDMITGLYSAS 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 158 VNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCK---HVSRPTslhTIPAHIEKAVRCAMYGRPGAVYVDLPGNLVL 234
Cdd:PRK11269 92 ADSIPILCITGQAPRARLHKEDFQAVDIESIAKPVTKwavTVREPA---LVPRVFQQAFHLMRSGRPGPVLIDLPFDVQV 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 235 TsteeEISFPPQV--PLPAPVSIPPIAEIEKAIDTLKSAKKPLVIVGKGAAWSErGATQVQQFLTKSKLPWLATPGGKGV 312
Cdd:PRK11269 169 A----EIEFDPDTyePLPVYKPAATRAQIEKALEMLNAAERPLIVAGGGVINAD-ASDLLVEFAELTGVPVIPTLMGWGA 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 313 ASDLHPRFIGQA------R--SLALREADTVFLIGARF-NwiLHFGLPPRFQKDVKVVQIDICPEefhQNVKTEVPLLGD 383
Cdd:PRK11269 244 IPDDHPLMAGMVglqtshRygNATLLASDFVLGIGNRWaN--RHTGSVEVYTKGRKFVHVDIEPT---QIGRVFGPDLGI 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 384 IGETLAELT------------PRLGDWtydesTEWFKKLREnaekNRAAVEKFVDDHSTPLNYYAAYQPIREFLANNDVI 451
Cdd:PRK11269 319 VSDAKAALEllvevarewkaaGRLPDR-----SAWVADCQE----RKRTLLRKTHFDNVPIKPQRVYEEMNKAFGRDTCY 389
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 452 VINEGANTMdIGRTMMPSRLPKRRLDAGTFGTMgvghGFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNL 531
Cdd:PRK11269 390 VSTIGLSQI-AAAQFLHVYKPRHWINCGQAGPL----GWTIPAALGVRAADPDRNVVALSGDYDFQFLIEELAVGAQFNL 464
|
490
....*....|....*..
gi 17531301 532 PVVTVIINNSgiYRGLL 548
Cdd:PRK11269 465 PYIHVLVNNA--YLGLI 479
|
|
| PRK08273 |
PRK08273 |
thiamine pyrophosphate protein; Provisional |
132-627 |
7.75e-22 |
|
thiamine pyrophosphate protein; Provisional
Pssm-ID: 181344 [Multi-domain] Cd Length: 597 Bit Score: 99.98 E-value: 7.75e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 132 TGKPVALLVVSGPGILHAIGGLANATVNCWPVVCIGGTadvdlENRGAFQEWSQQE-SVRNSCKHVSRP-----TSLHTI 205
Cdd:PRK08273 65 TGEVGVCLATSGPGAIHLLNGLYDAKLDHVPVVAIVGQ-----QARAALGGHYQQEvDLQSLFKDVAGAfvqmvTVPEQL 139
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 206 PAHIEKAVRCAMYGRPGAVyVDLPGNLvltsTEEEISFPPQ--------VPLPAPVSIPPIAEIEKAIDTLKSAKKPLVI 277
Cdd:PRK08273 140 RHLVDRAVRTALAERTVTA-VILPNDV----QELEYEPPPHahgtvhsgVGYTRPRVVPYDEDLRRAAEVLNAGRKVAIL 214
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 278 VGKGAawseRGAT----QVQQFL----TKSKLpwlatpgGKGVASDLHPRFIGQARSLA-------LREADTVFLIGARF 342
Cdd:PRK08273 215 VGAGA----LGATdeviAVAERLgagvAKALL-------GKAALPDDLPWVTGSIGLLGtkpsyelMRECDTLLMVGSSF 283
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 343 NWIlHFgLPPRFQkdVKVVQIDICPEEFHQNVKTEVPLLGDIGETLAELTPRLgdwTYDESTEWFKKLRENAEKNRAAVE 422
Cdd:PRK08273 284 PYS-EF-LPKEGQ--ARGVQIDIDGRMLGLRYPMEVNLVGDAAETLRALLPLL---ERKKDRSWRERIEKWVARWWETLE 356
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 423 KFVDDHSTPLNYYAAYQPIREFLANNDVIVINEG------ANTMDIGRTMMPSRlpkrrldAGTFGTMGVGHGFSLAAAL 496
Cdd:PRK08273 357 ARAMVPADPVNPQRVFWELSPRLPDNAILTADSGscanwyARDLRMRRGMMASL-------SGTLATMGPAVPYAIAAKF 429
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 497 wARDHSPktkVLVVQGDSAFGFSAM-ELETIARY-----NLPVVTVIINNsgiyrgllpED-------DKAIEGDRTL-- 561
Cdd:PRK08273 430 -AHPDRP---VIALVGDGAMQMNGMaELITVAKYwrqwsDPRLIVLVLNN---------RDlnqvtweQRVMEGDPKFea 496
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17531301 562 --ALPVLSltaecrYEEMCKAFGGAGTVVRTVPEIKAALEKAFQkTDGPTVINALisTDSERKPQADH 627
Cdd:PRK08273 497 sqDLPDVP------YARFAELLGLKGIRVDDPEQLGAAWDEALA-ADRPVVLEVK--TDPNVPPLPPH 555
|
|
| TPP_BFDC |
cd02002 |
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins ... |
449-615 |
1.14e-18 |
|
Thiamine pyrophosphate (TPP) family, BFDC subfamily, TPP-binding module; composed of proteins similar to Pseudomonas putida benzoylformate decarboxylase (BFDC). P. putida BFDC plays a role in the mandelate pathway, catalyzing the conversion of benzoylformate to benzaldehyde and carbon dioxide. This enzyme is dependent on TPP and a divalent metal cation as cofactors.
Pssm-ID: 238960 [Multi-domain] Cd Length: 178 Bit Score: 83.80 E-value: 1.14e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 449 DVIVINEGANTMDIGRTMMPSRLPKRRLdAGTFGTMGVGHGFSLAAALWARDHspktKVLVVQGDSAFGFSAMELETIAR 528
Cdd:cd02002 17 DAIIVDEAVTNGLPLRDQLPLTRPGSYF-TLRGGGLGWGLPAAVGAALANPDR----KVVAIIGDGSFMYTIQALWTAAR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 529 YNLPVVTVIINNSGiYRGL----------LPEDDKAIEGDrtLALPVLsltaecRYEEMCKAFGGAGTVVRTVPEIKAAL 598
Cdd:cd02002 92 YGLPVTVVILNNRG-YGALrsflkrvgpeGPGENAPDGLD--LLDPGI------DFAAIAKAFGVEAERVETPEELDEAL 162
|
170
....*....|....*..
gi 17531301 599 EKAFQKtDGPTVINALI 615
Cdd:cd02002 163 REALAE-GGPALIEVVV 178
|
|
| TPP_POX |
cd02014 |
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; ... |
431-618 |
9.97e-18 |
|
Thiamine pyrophosphate (TPP) family, Pyruvate oxidase (POX) subfamily, TPP-binding module; composed of proteins similar to Lactobacillus plantarum POX, which plays a key role in controlling acetate production under aerobic conditions. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate. It requires FAD in addition to TPP and a divalent cation as cofactors.
Pssm-ID: 238972 [Multi-domain] Cd Length: 178 Bit Score: 81.04 E-value: 9.97e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 431 PLNYYAAYQPIREFLANNDVIVINEGANTMDIGRTMMPSrlPKRRLD-AGTFGTMGVGhgfsLAAALWARDHSPKTKVLV 509
Cdd:cd02014 1 PIHPERVAAELNKRAPDDAIFTIDVGNVTVWAARHLRMN--GKQRFIlSGLLATMGNG----LPGAIAAKLAYPDRQVIA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 510 VQGDSAFGFSAMELETIARYNLPVVTVIINNSGIyrGLLP---EDDKAIEGDRTLALPVLSLTAEcryeemckAFGGAGT 586
Cdd:cd02014 75 LSGDGGFAMLMGDLITAVKYNLPVIVVVFNNSDL--GFIKweqEVMGQPEFGVDLPNPDFAKIAE--------AMGIKGI 144
|
170 180 190
....*....|....*....|....*....|..
gi 17531301 587 VVRTVPEIKAALEKAFqKTDGPTVINALISTD 618
Cdd:cd02014 145 RVEDPDELEAALDEAL-AADGPVVIDVVTDPN 175
|
|
| TPP_AHAS |
cd02015 |
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding ... |
472-618 |
1.02e-16 |
|
Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the acetohydroxyacid, 2-acetolactate. 2-Acetolactate is the precursor of the branched chain amino acids, valine and leucine. AHAS also catalyzes the condensation of pyruvate and 2-ketobutyrate to form 2-aceto-2-hydroxybutyrate in isoleucine biosynthesis. In addition to requiring TPP and a divalent metal ion as cofactors, AHAS requires FAD.
Pssm-ID: 238973 [Multi-domain] Cd Length: 186 Bit Score: 78.69 E-value: 1.02e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 472 PKRRLDAGTFGTMGvghgFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNS--GIYRGLlp 549
Cdd:cd02015 40 PRSWLTSGGLGTMG----FGLPAAIGAKVARPDKTVICIDGDGSFQMNIQELATAAQYNLPVKIVILNNGslGMVRQW-- 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 550 eddkaiegdrtlalpvLSLTAECRYEE-----------MCKAFGGAGTVVRTVPEIKAALEKAFqKTDGPTVINALISTD 618
Cdd:cd02015 114 ----------------QELFYEGRYSHttldsnpdfvkLAEAYGIKGLRVEKPEELEAALKEAL-ASDGPVLLDVLVDPE 176
|
|
| PRK07092 |
PRK07092 |
benzoylformate decarboxylase; Reviewed |
142-615 |
1.29e-16 |
|
benzoylformate decarboxylase; Reviewed
Pssm-ID: 235931 [Multi-domain] Cd Length: 530 Bit Score: 83.08 E-value: 1.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 142 SGPGILHAIGGLANATVNCWPVVCIGGT-------ADVDLENRGAfqewsqQESVRNSCKHVSRPTSLHTIPAHIEKAVR 214
Cdd:PRK07092 81 SAAGVGNAMGNLFTAFKNHTPLVITAGQqarsilpFEPFLAAVQA------AELPKPYVKWSIEPARAEDVPAAIARAYH 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 215 CAMYGRPGAVYVDLP--------GNLVLTSTEEEISfppqvplPAPvsippiAEIEKAIDTLKSAKKPLVIVGKG----A 282
Cdd:PRK07092 155 IAMQPPRGPVFVSIPyddwdqpaEPLPARTVSSAVR-------PDP------AALARLGDALDAARRPALVVGPAvdraG 221
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 283 AWSErgatqVQQFLTKSKLP-WLATPGGKGVASDLHPRFIG------QARSLALREADTVFLIGA---RFnwilH-FGLP 351
Cdd:PRK07092 222 AWDD-----AVRLAERHRAPvWVAPMSGRCSFPEDHPLFAGflpasrEKISALLDGHDLVLVIGApvfTY----HvEGPG 292
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 352 PRFQKDVKVVQIDICPEEfhqnvKTEVP----LLGDIGETLAELTPRLGDwtydestewfkkLRENAEKNRAAVEKFVDD 427
Cdd:PRK07092 293 PHLPEGAELVQLTDDPGE-----AAWAPmgdaIVGDIRLALRDLLALLPP------------SARPAPPARPMPPPAPAP 355
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 428 hSTPLNYYAAYQPIREfLANNDVIVINEGANTmdigRTMMPSRLPKRRldAGTFGTMGVGH-GFSLAAALWARDHSPKTK 506
Cdd:PRK07092 356 -GEPLSVAFVLQTLAA-LRPADAIVVEEAPST----RPAMQEHLPMRR--QGSFYTMASGGlGYGLPAAVGVALAQPGRR 427
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 507 VLVVQGDSAFGFSAMELETIARYNLPVVTVIINNSGiYrGLLPEDDKAIEGDRT--LALPVLSLTAecryeeMCKAFGGA 584
Cdd:PRK07092 428 VIGLIGDGSAMYSIQALWSAAQLKLPVTFVILNNGR-Y-GALRWFAPVFGVRDVpgLDLPGLDFVA------LARGYGCE 499
|
490 500 510
....*....|....*....|....*....|.
gi 17531301 585 GTVVRTVPEIKAALEKAFQkTDGPTVINALI 615
Cdd:PRK07092 500 AVRVSDAAELADALARALA-ADGPVLVEVEV 529
|
|
| TPP_PDC_IPDC |
cd02005 |
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of ... |
438-618 |
8.08e-15 |
|
Thiamine pyrophosphate (TPP) family, PDC_IPDC subfamily, TPP-binding module; composed of proteins similar to pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC). PDC, a key enzyme in alcoholic fermentation, catalyzes the conversion of pyruvate to acetaldehyde and CO2. It is able to utilize other 2-oxo acids as substrates. In plants and various plant-associated bacteria, IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway, a tryptophan-dependent biosynthetic route to indole-3-acetaldehyde (IAA). IPDC catalyzes the decarboxylation of IPA to IAA. Both PDC and IPDC depend on TPP and Mg2+ as cofactors.
Pssm-ID: 238963 [Multi-domain] Cd Length: 183 Bit Score: 72.95 E-value: 8.08e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 438 YQPIREFLANNDVIVinegANTMDIGRTMMPSRLPK--RRLDAGTFGTMGvghgFSLAAALWARDHSPKTKVLVVQGDSA 515
Cdd:cd02005 8 WQQVQNFLKPNDILV----AETGTSWFGALDLKLPKgtRFISQPLWGSIG----YSVPAALGAALAAPDRRVILLVGDGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 516 FGFSAMELETIARYNLPVVTVIINNSGiYrgllpEDDKAIEGDRtlalpvlsltaEC-------RYEEMCKAFGGA---- 584
Cdd:cd02005 80 FQMTVQELSTMIRYGLNPIIFLINNDG-Y-----TIERAIHGPE-----------ASyndianwNYTKLPEVFGGGgggl 142
|
170 180 190
....*....|....*....|....*....|....
gi 17531301 585 GTVVRTVPEIKAALEKAFQKTDGPTVINALISTD 618
Cdd:cd02005 143 SFRVKTEGELDEALKDALFNRDKLSLIEVILPKD 176
|
|
| TPP_PYR_POX |
cd07039 |
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) ... |
82-232 |
2.67e-14 |
|
Pyrimidine (PYR) binding domain of POX; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate oxidase (POX) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. Lactobacillus plantarum POX is a homotetramer (dimer-of-homodimers), having two active sites per homodimer lying between PYR and PP domains of different subunits. POX decarboxylates pyruvate, producing hydrogen peroxide and the energy-storage metabolite acetylphosphate.
Pssm-ID: 132922 [Multi-domain] Cd Length: 164 Bit Score: 71.04 E-value: 2.67e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVGFPVIEVGMAAQAHG-IKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGILHAIGGLANATVNC 160
Cdd:cd07039 10 LENWGVKRVYGIPGDSINGLMDALRREGkIEFIQVRHEEAAAFAASAEAKLTGKLGVCLGSSGPGAIHLLNGLYDAKRDR 89
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 17531301 161 WPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAmYGRPGAVYVDLPGNL 232
Cdd:cd07039 90 APVLAIAGQVPTDELGTDYFQEVDLLALFKDVAVYNETVTSPEQLPELLDRAIRTA-IAKRGVAVLILPGDV 160
|
|
| TPP_Xsc_like |
cd02013 |
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of ... |
449-625 |
5.08e-14 |
|
Thiamine pyrophosphate (TPP) family, Xsc-like subfamily, TPP-binding module; composed of proteins similar to Alcaligenes defragrans sulfoacetaldehyde acetyltransferase (Xsc). Xsc plays a key role in the degradation of taurine, catalyzing the desulfonation of 2-sulfoacetaldehyde into sulfite and acetyl phosphate. This enzyme requires TPP and divalent metal ions for activity.
Pssm-ID: 238971 [Multi-domain] Cd Length: 196 Bit Score: 71.00 E-value: 5.08e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 449 DVIVINEGANTMDIGRTMMPSRLPKRRLDAGTFGTMGvghgFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIAR 528
Cdd:cd02013 20 DAIVSTDIGNICSVANSYLRFEKPRSFIAPLSFGNCG----YALPAIIGAKAAAPDRPVVAIAGDGAWGMSMMEIMTAVR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 529 YNLPVVTVIINNsgiyRGLLPEDDKAIE--GDRTLALPVLSLtaecRYEEMCKAFGGAGTVVRTVPEIKAALEKAF--QK 604
Cdd:cd02013 96 HKLPVTAVVFRN----RQWGAEKKNQVDfyNNRFVGTELESE----SFAKIAEACGAKGITVDKPEDVGPALQKAIamMA 167
|
170 180
....*....|....*....|....*....
gi 17531301 605 TDGPTVINALIS--------TDSERKPQA 625
Cdd:cd02013 168 EGKTTVIEIVCDqelgdpfrRDALKKPVR 196
|
|
| TPP_ALS |
cd02010 |
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; ... |
441-612 |
2.84e-13 |
|
Thiamine pyrophosphate (TPP) family, Acetolactate synthase (ALS) subfamily, TPP-binding module; composed of proteins similar to Klebsiella pneumoniae ALS, a catabolic enzyme required for butanediol fermentation. ALS catalyzes the conversion of 2 molecules of pyruvate to acetolactate and carbon dioxide. ALS does not contain FAD, and requires TPP and a divalent metal cation for activity.
Pssm-ID: 238968 [Multi-domain] Cd Length: 177 Bit Score: 68.47 E-value: 2.84e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 441 IREFLANNDVIVINEGANTMDIGRtMMPSRLPKRRLDAGTFGTMGVGHGFSLAAALwARdhsPKTKVLVVQGDSAFGFSA 520
Cdd:cd02010 8 LRAVMGDDDIVLLDVGAHKIWMAR-YYRTYAPNTCLISNGLATMGVALPGAIGAKL-VY---PDRKVVAVSGDGGFMMNS 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 521 MELETIARYNLPVVTVIINNSGiYrGLLpEDDKAIEGDRTLAL----PVLSLTAEcryeemckAFGGAGTVVRTVPEIKA 596
Cdd:cd02010 83 QELETAVRLKIPLVVLIWNDNG-Y-GLI-KWKQEKEYGRDSGVdfgnPDFVKYAE--------SFGAKGYRIESADDLLP 151
|
170
....*....|....*.
gi 17531301 597 ALEKAFqKTDGPTVIN 612
Cdd:cd02010 152 VLERAL-AADGVHVID 166
|
|
| TPP_enzyme_PYR |
cd06586 |
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine ... |
77-230 |
2.91e-11 |
|
Pyrimidine (PYR) binding domain of thiamine pyrophosphate (TPP)-dependent enzymes; Thiamine pyrophosphate (TPP) family, pyrimidine (PYR) binding domain; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. A polar interaction between the conserved glutamate of the PYR domain and the N1' of the TPP aminopyrimidine ring is shared by most TPP-dependent enzymes, and participates in the activation of TPP. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this group. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. In the case of 2-oxoisovalerate dehydrogenase (2OXO), sulfopyruvate decarboxylase (ComDE), and the E1 component of human pyruvate dehydrogenase complex (E1- PDHc) the PYR and PP domains appear on different subunits. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites. For many of these enzymes the active sites lie between PP and PYR domains on different subunits. However, for the homodimeric enzymes 1-deoxy-D-xylulose 5-phosphate synthase (DXS) and Desulfovibrio africanus pyruvate:ferredoxin oxidoreductase (PFOR), each active site lies at the interface of the PYR and PP domains from the same subunit.
Pssm-ID: 132915 [Multi-domain] Cd Length: 154 Bit Score: 61.98 E-value: 2.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 77 ITAAALKSQGVEYMFGVVGFPVIEVGMAAQAH-GIKYIGCRNEQAAAYAAQAMGYLTGKPVALlVVSGPGILHAIGGLAN 155
Cdd:cd06586 2 AFAEVLTAWGVRHVFGYPGDEISSLLDALREGdKRIIDTVIHELGAAGAAAGYARAGGPPVVI-VTSGTGLLNAINGLAD 80
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17531301 156 ATVNCWPVVCIGGTADVDLENRGAFQEWSQQESVRNSCKHVSRPTSLHTIPAHIEKAVRCAmYGRPGAVYVDLPG 230
Cdd:cd06586 81 AAAEHLPVVFLIGARGISAQAKQTFQSMFDLGMYRSIPEANISSPSPAELPAGIDHAIRTA-YASQGPVVVRLPR 154
|
|
| PRK07586 |
PRK07586 |
acetolactate synthase large subunit; |
129-615 |
1.90e-10 |
|
acetolactate synthase large subunit;
Pssm-ID: 236063 [Multi-domain] Cd Length: 514 Bit Score: 63.71 E-value: 1.90e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 129 GY--LTGKPVALLVVSGPGILHAIGGLANATVNCWPVVCIGG-------------TADVdlenrgafqewsqqESV-RNS 192
Cdd:PRK07586 57 GYarMAGKPAATLLHLGPGLANGLANLHNARRARTPIVNIVGdhatyhrkydaplTSDI--------------EALaRPV 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 193 CKHVSRPTSLHTIPAHIEKAVRCAMyGRPGAVYVD-LPGNlvlTSTEEEISFPPQVPLPAPVSIPPIAeIEKAIDTLKSA 271
Cdd:PRK07586 123 SGWVRRSESAADVAADAAAAVAAAR-GAPGQVATLiLPAD---VAWSEGGPPAPPPPAPAPAAVDPAA-VEAAAAALRSG 197
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 272 KKPLVIVGkGAAWSERGATQVQQFLTKSKLPWLA------TPGGKGVAS-DLHPRFIGQARSlALREADTVFLIGAR--- 341
Cdd:PRK07586 198 EPTVLLLG-GRALRERGLAAAARIAAATGARLLAetfparMERGAGRPAvERLPYFAEQALA-QLAGVRHLVLVGAKapv 275
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 342 -FnwilhFGLPprfQKDVKVVqidicPEEfhqnvkTEVPLLGDIGE----TLAELTPRLGDWTYDESTewfkklrenAEK 416
Cdd:PRK07586 276 aF-----FAYP---GKPSRLV-----PEG------CEVHTLAGPGEdaaaALEALADALGAKPAAPPL---------AAP 327
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 417 NRAAVEkfvddhSTPLNYYAAYQPIREFLANNDvIVINEGANTmdiGRTMMPSRLPKRRLDAGTFgtMGVGHGFSLAAAL 496
Cdd:PRK07586 328 ARPPLP------TGALTPEAIAQVIAALLPENA-IVVDESITS---GRGFFPATAGAAPHDWLTL--TGGAIGQGLPLAT 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 497 WARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNsGIYRGLLPEDDK--AIE-GDRTLAL-----PVLSL 568
Cdd:PRK07586 396 GAAVACPDRKVLALQGDGSAMYTIQALWTQARENLDVTTVIFAN-RAYAILRGELARvgAGNpGPRALDMldlddPDLDW 474
|
490 500 510 520
....*....|....*....|....*....|....*....|....*..
gi 17531301 569 TAecryeeMCKAFGGAGTVVRTVPEIKAALEKAFQKTdGPTVINALI 615
Cdd:PRK07586 475 VA------LAEGMGVPARRVTTAEEFADALAAALAEP-GPHLIEAVV 514
|
|
| TPP_Gcl |
cd02006 |
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins ... |
463-601 |
1.23e-07 |
|
Thiamine pyrophosphate (TPP) family, Gcl subfamily, TPP-binding module; composed of proteins similar to Escherichia coli glyoxylate carboligase (Gcl). E. coli glyoxylate carboligase, plays a key role in glyoxylate metabolism where it catalyzes the condensation of two molecules of glyoxylate to give tartronic semialdehyde and carbon dioxide. This enzyme requires TPP, magnesium ion and FAD as cofactors.
Pssm-ID: 238964 [Multi-domain] Cd Length: 202 Bit Score: 52.67 E-value: 1.23e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 463 GRTMMPSRLPKRRLDAGTFGTMGvghgFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVIINNSg 542
Cdd:cd02006 38 GAQMLHVYKPRHWINCGQAGPLG----WTVPAALGVAAADPDRQVVALSGDYDFQFMIEELAVGAQHRIPYIHVLVNNA- 112
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17531301 543 iYRGLLPEDDKAIEGDR--TLALPVLSLTAECRYE----EMCKAFGGAGTVVRTVPEIKAALEKA 601
Cdd:cd02006 113 -YLGLIRQAQRAFDMDYqvNLAFENINSSELGGYGvdhvKVAEGLGCKAIRVTKPEELAAAFEQA 176
|
|
| PRK12474 |
PRK12474 |
hypothetical protein; Provisional |
69-615 |
1.32e-06 |
|
hypothetical protein; Provisional
Pssm-ID: 139002 [Multi-domain] Cd Length: 518 Bit Score: 51.41 E-value: 1.32e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 69 GSNMDGASITAAALKSQGVEYMFGVVGFPVIE-VGMAAQAHGIKYIGCRNEQAAAYAAQAMGYLTGKPVALLVVSGPGIL 147
Cdd:PRK12474 2 GQTMNGADSVVDTLLNCGVEVCFANPGTSEMHfVAALDRVPRMRPVLCLFEGVVTGAADGYGRIAGKPAVTLLHLGPGLA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 148 HAIGGLANATVNCWPVVCIGG-------------TADVDLENRgAFQEWsqqesvrnsckhVSRPTSLHTIPAHIEKAVR 214
Cdd:PRK12474 82 NGLANLHNARRAASPIVNIVGdhavehlqydaplTSDIDGFAR-PVSRW------------VHRSASAGAVDSDVARAVQ 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 215 CAMYGRPGAVYVDLPGNLVLTSTEEEISFPPQVPlPAPVSIPPIAEIEKAIDTlksaKKPLVIVGKGAAWSERGATQVQQ 294
Cdd:PRK12474 149 AAQSAPGGIATLIMPADVAWNEAAYAAQPLRGIG-PAPVAAETVERIAALLRN----GKKSALLLRGSALRGAPLEAAGR 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 295 FLTKSKLPWLA------TPGGKGVASDLHPRFIGQARSLALREADTVFLIGAR--FNWILHFGLPPRF-QKDVKVVQIDI 365
Cdd:PRK12474 224 IQAKTGVRLYCdtfaprIERGAGRVPIERIPYFHEQITAFLKDVEQLVLVGAKppVSFFAYPGKPSWGaPPGCEIVYLAQ 303
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 366 CPEEFHQNVKtevpllgdigetlaeltprlgdWTYDEStewfkklreNAEKNRAAVEKFV--DDHSTPLNYYAAYQPIRE 443
Cdd:PRK12474 304 PDEDLAQALQ----------------------DLADAV---------DAPAEPAARTPLAlpALPKGALNSLGVAQLIAH 352
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 444 FLANNdVIVINEGANTMDIGRTMMPSRLPKRRLDAgTFGTMGVGHGFSLAAALWArdhsPKTKVLVVQGDSAFGFSAMEL 523
Cdd:PRK12474 353 RTPDQ-AIYADEALTSGLFFDMSYDRARPHTHLPL-TGGSIGQGLPLAAGAAVAA----PDRKVVCPQGDGGAAYTMQAL 426
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 524 ETIARYNLPVVTVIINNSGiYRGLLPEDDK-AIEGDRTLALPVLSL-TAECRYEEMCKAFGGAGTVVRTVPEIKAALEKA 601
Cdd:PRK12474 427 WTMARENLDVTVVIFANRS-YAILNGELQRvGAQGAGRNALSMLDLhNPELNWMKIAEGLGVEASRATTAEEFSAQYAAA 505
|
570
....*....|....
gi 17531301 602 FQKTdGPTVINALI 615
Cdd:PRK12474 506 MAQR-GPRLIEAMI 518
|
|
| TPP_PYR_PDC_IPDC_like |
cd07038 |
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase ... |
82-229 |
7.41e-05 |
|
Pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC), indolepyruvate decarboxylase (IPDC) and related proteins; Thiamine pyrophosphate (TPP family), pyrimidine (PYR) binding domain of pyruvate decarboxylase (PDC) and indolepyruvate decarboxylase (IPDC) subfamily. The PYR domain is found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. TPP binds in the cleft formed by a PYR domain and a PP domain. The PYR domain, binds the aminopyrimidine ring of TPP, the PP domain binds the diphosphate residue. The PYR and PP domains have a common fold, but do not share strong sequence conservation. The PP domain is not included in this sub-family. Most TPP-dependent enzymes have the PYR and PP domains on the same subunit although these domains can be alternatively arranged in the primary structure. TPP-dependent enzymes are multisubunit proteins, the smallest catalytic unit being a dimer-of-active sites, for many the active sites lie between PP and PYR domains on different subunits. PDC catalyzes the conversion of pyruvate to acetaldehyde and CO2 in alcoholic fermentation. IPDC plays a role in the indole-3-pyruvic acid (IPA) pathway in plants and various plant-associated bacteria, it catalyzes the decarboxylation of IPA to IAA. Also belonging to this group is Mycobacterium tuberculosis alpha-keto acid decarboxylase (MtKDC) which participates in amino acid degradation via the Ehrlich pathway, and Lactococcus lactis branched-chain keto acid decarboxylase (KdcA) an enzyme identified as being involved in cheese ripening, which exhibits a very broad substrate range in the decarboxylation and carboligation reactions.
Pssm-ID: 132921 [Multi-domain] Cd Length: 162 Bit Score: 43.64 E-value: 7.41e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 82 LKSQGVEYMFGVVG---FPVIEvgMAAQAHGIKYIGCRNEQAAayaaqamGYLT-G----KPVALLVVS-GPGILHAIGG 152
Cdd:cd07038 7 LKQLGVKHVFGVPGdynLPLLD--AIEENPGLRWVGNCNELNA-------GYAAdGyarvKGLGALVTTyGVGELSALNG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 153 LANATVNCWPVVCIGGTADVDLENRGA----------FQewSQQESVRNSCKHVSRPTSLHTIPAHIEKAVR-CAMYGRP 221
Cdd:cd07038 78 IAGAYAEHVPVVHIVGAPSTKAQASGLllhhtlgdgdFD--VFLKMFEEITCAAARLTDPENAAEEIDRVLRtALRESRP 155
|
....*...
gi 17531301 222 gaVYVDLP 229
Cdd:cd07038 156 --VYIEIP 161
|
|
| PLN02573 |
PLN02573 |
pyruvate decarboxylase |
109-542 |
7.80e-05 |
|
pyruvate decarboxylase
Pssm-ID: 215311 [Multi-domain] Cd Length: 578 Bit Score: 45.85 E-value: 7.80e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 109 GIKYIGCRNEQAAAYAAQamGYLTGKPVALLVVS----GPGILHAIGGlanATVNCWPVVCI-GGTADVDL-ENR----- 177
Cdd:PLN02573 54 GLNLIGCCNELNAGYAAD--GYARARGVGACVVTftvgGLSVLNAIAG---AYSENLPVICIvGGPNSNDYgTNRilhht 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 178 ----------GAFQEWSQQESVRNsckhvsrptslHTIPAH--IEKAVRCAMyGRPGAVYVDLPGNLVltsteeEISFPP 245
Cdd:PLN02573 129 iglpdfsqelRCFQTVTCYQAVIN-----------NLEDAHelIDTAISTAL-KESKPVYISVSCNLA------AIPHPT 190
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 246 QVPLPAPVSIPPI--------AEIEKAIDTLKSAKKPlVIVGKGAAWSERGATQVQQFLTKSKLPWLATPGGKGVASDLH 317
Cdd:PLN02573 191 FSREPVPFFLTPRlsnkmsleAAVEAAAEFLNKAVKP-VLVGGPKLRVAKACKAFVELADASGYPVAVMPSAKGLVPEHH 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 318 PRFIGQ---ARSLA-----LREADTVFLIGARFNWILHFGLPPRFQKDvKVVQIDicPEEFhqnVKTEVPLLGDIgetla 389
Cdd:PLN02573 270 PHFIGTywgAVSTPfcaeiVESADAYLFAGPIFNDYSSVGYSLLLKKE-KAIIVQ--PDRV---TIGNGPAFGCV----- 338
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 390 eltprlgdwtydESTEWFKKLRENAEKNRAAVEKF-----------VDDHSTPLNYYAAYQPIREFLANNDVIVinegAN 458
Cdd:PLN02573 339 ------------LMKDFLEALAKRVKKNTTAYENYkrifvpegeplKSEPGEPLRVNVLFKHIQKMLSGDTAVI----AE 402
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 459 TMDIGRTMMPSRLPKrrlDAGTFGTMGVGH-GFSLAAALWARDHSPKTKVLVVQGDSAFGFSAMELETIARYNLPVVTVI 537
Cdd:PLN02573 403 TGDSWFNCQKLKLPE---GCGYEFQMQYGSiGWSVGATLGYAQAAPDKRVIACIGDGSFQVTAQDVSTMIRCGQKSIIFL 479
|
....*
gi 17531301 538 INNSG 542
Cdd:PLN02573 480 INNGG 484
|
|
| TPP_SHCHC_synthase |
cd02009 |
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of ... |
445-611 |
3.32e-04 |
|
Thiamine pyrophosphate (TPP) family, SHCHC synthase subfamily, TPP-binding module; composed of proteins similar to Escherichia coli 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylic acid (SHCHC) synthase (also called MenD). SHCHC synthase plays a key role in the menaquinone biosynthetic pathway, converting isochorismate and 2-oxoglutarate to SHCHC, pyruvate and carbon dioxide. The enzyme requires TPP and a divalent metal cation for activity.
Pssm-ID: 238967 [Multi-domain] Cd Length: 175 Bit Score: 41.81 E-value: 3.32e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 445 LANNDVIVInegANTMDIgR---TMMPSRLPKRRLDA--GTFG---TMGVGHGFSLAaalwardhSPKTKVLVVqGDSAF 516
Cdd:cd02009 14 LPEGSQLFV---GNSMPI-RdldLFALPSDKTVRVFAnrGASGidgTLSTALGIALA--------TDKPTVLLT-GDLSF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17531301 517 GFSAMELETIARYNLPVVTVIINNSG--IYRgLLPEDDKAIEGDRTLALPvLSLTaecrYEEMCKAFGGAGTVVRTVPEI 594
Cdd:cd02009 81 LHDLNGLLLGKQEPLNLTIVVINNNGggIFS-LLPQASFEDEFERLFGTP-QGLD----FEHLAKAYGLEYRRVSSLDEL 154
|
170
....*....|....*..
gi 17531301 595 KAALEKAFQkTDGPTVI 611
Cdd:cd02009 155 EQALESALA-QDGPHVI 170
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