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Conserved domains on  [gi|17556134|ref|NP_497687|]
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SAP domain-containing protein [Caenorhabditis elegans]

Protein Classification

SAP domain-containing protein( domain architecture ID 10488483)

SAP (SAF-A/B, Acinus and PIAS) domain-containing protein may bind DNA or RNA and act as a transcriptional regulator

CATH:  1.10.720.30
Gene Ontology:  GO:0003676|GO:0003700
PubMed:  10694879
SCOP:  4002795

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
9-42 1.05e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


:

Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.71  E-value: 1.05e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17556134     9 KKLTVPRLKEELASRGLDNTGNKPELLARLTESI 42
Cdd:pfam02037   2 SKLTVAELKEELRKRGLPTSGKKAELIERLQEYL 35
PLN03124 super family cl33640
poly [ADP-ribose] polymerase; Provisional
8-86 3.53e-05

poly [ADP-ribose] polymerase; Provisional


The actual alignment was detected with superfamily member PLN03124:

Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 44.44  E-value: 3.53e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17556134    8 AKKLTVPRLKEELASRGLDNTGNKPELLARLTESIEQaadellgDAGITSDTHLLSDDILNDDILDAPSVGDESEADKL 86
Cdd:PLN03124   2 ANKLKVDELRAALAKRGLDTTGLKAALVRRLDDAIAE-------DAKTASKSGTKSSAGRKKRRERQDDGDDEPVSPKR 73
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
9-42 1.05e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.71  E-value: 1.05e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17556134     9 KKLTVPRLKEELASRGLDNTGNKPELLARLTESI 42
Cdd:pfam02037   2 SKLTVAELKEELRKRGLPTSGKKAELIERLQEYL 35
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
9-42 2.68e-07

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 45.94  E-value: 2.68e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 17556134      9 KKLTVPRLKEELASRGLDNTGNKPELLARLTESI 42
Cdd:smart00513   2 AKLKVSELKDELKKRGLSTSGTKAELVDRLLEAL 35
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
8-86 3.53e-05

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 44.44  E-value: 3.53e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17556134    8 AKKLTVPRLKEELASRGLDNTGNKPELLARLTESIEQaadellgDAGITSDTHLLSDDILNDDILDAPSVGDESEADKL 86
Cdd:PLN03124   2 ANKLKVDELRAALAKRGLDTTGLKAALVRRLDDAIAE-------DAKTASKSGTKSSAGRKKRRERQDDGDDEPVSPKR 73
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
5-47 1.58e-03

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 39.44  E-value: 1.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 17556134    5 VADAKKLTVPRLKEELASRGLDNTGNKPELLARLTESIEQAAD 47
Cdd:PLN03124  76 IDEVKGMTVRELREAASERGLATTGRKKDLLERLCAALESDVK 118
 
Name Accession Description Interval E-value
SAP pfam02037
SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding ...
9-42 1.05e-08

SAP domain; The SAP (after SAF-A/B, Acinus and PIAS) motif is a putative DNA/RNA binding domain found in diverse nuclear and cytoplasmic proteins.


Pssm-ID: 460424 [Multi-domain]  Cd Length: 35  Bit Score: 49.71  E-value: 1.05e-08
                          10        20        30
                  ....*....|....*....|....*....|....
gi 17556134     9 KKLTVPRLKEELASRGLDNTGNKPELLARLTESI 42
Cdd:pfam02037   2 SKLTVAELKEELRKRGLPTSGKKAELIERLQEYL 35
SAP smart00513
Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;
9-42 2.68e-07

Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation;


Pssm-ID: 128789 [Multi-domain]  Cd Length: 35  Bit Score: 45.94  E-value: 2.68e-07
                           10        20        30
                   ....*....|....*....|....*....|....
gi 17556134      9 KKLTVPRLKEELASRGLDNTGNKPELLARLTESI 42
Cdd:smart00513   2 AKLKVSELKDELKKRGLSTSGTKAELVDRLLEAL 35
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
8-86 3.53e-05

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 44.44  E-value: 3.53e-05
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17556134    8 AKKLTVPRLKEELASRGLDNTGNKPELLARLTESIEQaadellgDAGITSDTHLLSDDILNDDILDAPSVGDESEADKL 86
Cdd:PLN03124   2 ANKLKVDELRAALAKRGLDTTGLKAALVRRLDDAIAE-------DAKTASKSGTKSSAGRKKRRERQDDGDDEPVSPKR 73
PLN03124 PLN03124
poly [ADP-ribose] polymerase; Provisional
5-47 1.58e-03

poly [ADP-ribose] polymerase; Provisional


Pssm-ID: 215591 [Multi-domain]  Cd Length: 643  Bit Score: 39.44  E-value: 1.58e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 17556134    5 VADAKKLTVPRLKEELASRGLDNTGNKPELLARLTESIEQAAD 47
Cdd:PLN03124  76 IDEVKGMTVRELREAASERGLATTGRKKDLLERLCAALESDVK 118
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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