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Conserved domains on  [gi|17554744|ref|NP_498584|]
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Large ribosomal subunit protein eL6 [Caenorhabditis elegans]

Protein Classification

60S ribosomal protein L6( domain architecture ID 10192145)

60S ribosomal protein L6 is a component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell

Gene Ontology:  GO:0015934|GO:0006412|GO:0003735
PubMed:  24524803|11290319
SCOP:  4006169

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
 63-217 2.53e-76

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


:

Pssm-ID: 240520  Cd Length: 152  Bit Score: 226.66  E-value: 2.53e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554744  63 KTVTLRKTLTPGTVLIVLAGRHKGKRVVFLKQLPqSGLLLVTGPHKINGFPLRRIGQAFVIATSLKVNVSGVKIPeHIND 142
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLD-SGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLND 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17554744 143 EYFKRKSTAQKTGKN--IFASGKTEYTVSEQRKKDIKTVDAPILAAIKKHPehkFLFGYLGTRFSLGKNQYPHKMQF 217
Cdd:cd13156  79 AYFKRKKKKKKKKKEgeFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVP---LLKGYLKSRFSLRNGDYPHKMKF 152
 
Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
 63-217 2.53e-76

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


Pssm-ID: 240520  Cd Length: 152  Bit Score: 226.66  E-value: 2.53e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554744  63 KTVTLRKTLTPGTVLIVLAGRHKGKRVVFLKQLPqSGLLLVTGPHKINGFPLRRIGQAFVIATSLKVNVSGVKIPeHIND 142
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLD-SGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLND 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17554744 143 EYFKRKSTAQKTGKN--IFASGKTEYTVSEQRKKDIKTVDAPILAAIKKHPehkFLFGYLGTRFSLGKNQYPHKMQF 217
Cdd:cd13156  79 AYFKRKKKKKKKKKEgeFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVP---LLKGYLKSRFSLRNGDYPHKMKF 152
Ribosomal_L6e pfam01159
Ribosomal protein L6e;
109-217 2.23e-50

Ribosomal protein L6e;


Pssm-ID: 460089  Cd Length: 109  Bit Score: 159.23  E-value: 2.23e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554744   109 INGFPLRRIGQAFVIATSLKVNVSGVKIPEHINDEYFKR---KSTAQKTGKNIFASGKTEYTVSEQRKKDIKTVDAPILA 185
Cdd:pfam01159   1 VNGVPLRRVNQRYVIATSTKVDISGVKIPEHINDAYFKKekkKKKKPKSEEEFFEEKKEKKEVSEQRKADQKAVDKALLA 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 17554744   186 AIKKHPehkFLFGYLGTRFSLGKNQYPHKMQF 217
Cdd:pfam01159  81 AIKKVP---LLKGYLKSSFSLRKGDYPHEMKF 109
 
Name Accession Description Interval E-value
KOW_RPL6 cd13156
KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as ...
 63-217 2.53e-76

KOW motif of Ribosomal Protein L6; RPL6 contains KOW motif that has an extra ribosomal role as an oncogenic. KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4.


Pssm-ID: 240520  Cd Length: 152  Bit Score: 226.66  E-value: 2.53e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554744  63 KTVTLRKTLTPGTVLIVLAGRHKGKRVVFLKQLPqSGLLLVTGPHKINGFPLRRIGQAFVIATSLKVNVSGVKIPeHIND 142
Cdd:cd13156   1 KPRKLRSSITPGTVLILLAGRFRGKRVVFLKQLD-SGLLLVTGPFKINGVPLRRVNQRYVIATSTKVDISGVKVP-KLND 78

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17554744 143 EYFKRKSTAQKTGKN--IFASGKTEYTVSEQRKKDIKTVDAPILAAIKKHPehkFLFGYLGTRFSLGKNQYPHKMQF 217
Cdd:cd13156  79 AYFKRKKKKKKKKKEgeFFEEKKKKYVVSEERKEDQKAVDAALLAAIKKVP---LLKGYLKSRFSLRNGDYPHKMKF 152
Ribosomal_L6e pfam01159
Ribosomal protein L6e;
109-217 2.23e-50

Ribosomal protein L6e;


Pssm-ID: 460089  Cd Length: 109  Bit Score: 159.23  E-value: 2.23e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17554744   109 INGFPLRRIGQAFVIATSLKVNVSGVKIPEHINDEYFKR---KSTAQKTGKNIFASGKTEYTVSEQRKKDIKTVDAPILA 185
Cdd:pfam01159   1 VNGVPLRRVNQRYVIATSTKVDISGVKIPEHINDAYFKKekkKKKKPKSEEEFFEEKKEKKEVSEQRKADQKAVDKALLA 80

                          90       100       110
                  ....*....|....*....|....*....|..
gi 17554744   186 AIKKHPehkFLFGYLGTRFSLGKNQYPHKMQF 217
Cdd:pfam01159  81 AIKKVP---LLKGYLKSSFSLRKGDYPHEMKF 109
KOW cd00380
KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known ...
 74-123 4.73e-05

KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); KOW domain is known as an RNA-binding motif that is shared so far among some families of ribosomal proteins, the essential bacterial transcriptional elongation factor NusG, the eukaryotic chromatin elongation factor Spt5, the higher eukaryotic KIN17 proteins and Mtr4. The KOW motif contains an invariants glycine residue and comprises alternating blocks of hydrophilic and hydrophobic residues.


Pssm-ID: 240504  Cd Length: 49  Bit Score: 39.51  E-value: 4.73e-05
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|
gi 17554744  74 GTVLIVLAGRHKGKRVVFLKQLPQSGLLLVTGPHKINGfPLRRIGQAFVI 123
Cdd:cd00380   1 GDVVRVLRGPYKGREGVVVDIDPRFGIVTVKGATGSKG-AELKVRFDDVD 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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