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Conserved domains on  [gi|71996902|ref|NP_500133|]
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Nematode cuticle collagen N-terminal domain-containing protein [Caenorhabditis elegans]

Protein Classification

cuticular collagen family protein( domain architecture ID 18387949)

cuticular collagen family protein is a structural macromolecule of the extracellular matrix containing triple helix domains that form tight interactions and stabilize supramolecular aggregates

Gene Ontology:  GO:0042302|GO:0005581
PubMed:  1916105|21421911

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
gly_rich_SclB super family cl45768
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 90-284 5.12e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


The actual alignment was detected with superfamily member NF038329:

Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 68.78  E-value: 5.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   90 GGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGD 169
Cdd:NF038329 144 GPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGE 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  170 AGSDGSPGAP--GSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPitpgaPGPAGPPGPQGPPGAPGQPGHDGQP 247
Cdd:NF038329 224 DGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPAGKDGQNGKDGLP 298

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 71996902  248 GTPGPKGPNGNPGAPGADGNPGTPGVAGVAGSGGEKG 284
Cdd:NF038329 299 GKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.08e-11

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


:

Pssm-ID: 198156  Cd Length: 53  Bit Score: 59.02  E-value: 1.08e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71996902     12 FVAYSAVAFSVVAVISVSVTLPMVYNYVHHVKRSMQTEINFCKGSAKDIWTEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 90-284 5.12e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 68.78  E-value: 5.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   90 GGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGD 169
Cdd:NF038329 144 GPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGE 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  170 AGSDGSPGAP--GSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPitpgaPGPAGPPGPQGPPGAPGQPGHDGQP 247
Cdd:NF038329 224 DGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPAGKDGQNGKDGLP 298

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 71996902  248 GTPGPKGPNGNPGAPGADGNPGTPGVAGVAGSGGEKG 284
Cdd:NF038329 299 GKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 107-269 1.70e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.24  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  107 PGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPagdagsDGSPGAPGSDGQPG 186
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGE------AGAKGPAGEKGPQG 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  187 AAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPITPGAPGPAGPPGPQGPPGAPGQPGHDGQPGTPGPKGPNGNPGAPGADG 266
Cdd:NF038329 196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275


                 ...
gi 71996902  267 NPG 269
Cdd:NF038329 276 KDG 278
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.08e-11

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 59.02  E-value: 1.08e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71996902     12 FVAYSAVAFSVVAVISVSVTLPMVYNYVHHVKRSMQTEINFCKGSAKDIWTEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 31-64 4.65e-10

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 54.39  E-value: 4.65e-10
                          10        20        30
                  ....*....|....*....|....*....|....
gi 71996902    31 TLPMVYNYVHHVKRSMQTEINFCKGSAKDIWTEV 64
Cdd:pfam01484  17 TLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 77-271 5.29e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.84  E-value: 5.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   77 TARQAGYDAGVNGGGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQG 156
Cdd:PRK07764 585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  157 PAGPPGPPGPAGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPITPGAPGPAGPPGPQGPPG 236
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPE 744

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 71996902  237 APGQPGHDGQPGTPGPKGPNGNPGAPGADGNPGTP 271
Cdd:PRK07764 745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 106-219 1.33e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.44  E-value: 1.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  106 LPGAAGPAGTPGKPGRPGKAGAPGLPGNPGrppqqpcepitpPPCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSDGQ- 184
Cdd:NF038329 240 DPGPTGEDGPQGPDGPAGKDGPRGDRGEAG------------PDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQn 307

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 71996902  185 --PGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPIT 219
Cdd:NF038329 308 gkDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKT 344
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 174-215 3.98e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 3.98e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 71996902   174 GSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKS 215
Cdd:pfam01391  10 GPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAP 51
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 167-271 7.46e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  167 AGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPitPGAPGPAGPPGPQGPPGAPGQPGHDGQ 246
Cdd:NF038329 128 AGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGK--DGEAGAKGPAGEKGPQGPRGETGPAGE 205

                         90       100
                 ....*....|....*....|....*
gi 71996902  247 PGTPGPKGPNGNPGAPGADGNPGTP 271
Cdd:NF038329 206 QGPAGPAGPDGEAGPAGEDGPAGPA 230
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 108-219 8.37e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 8.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  108 GAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSDGQPGA 187
Cdd:NF038329 260 GPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGK 339

                         90       100       110
                 ....*....|....*....|....*....|..
gi 71996902  188 AGDKGPAGPNGNPGAPGSPGKPGEDGKSEPIT 219
Cdd:NF038329 340 PAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVT 371
 
Name Accession Description Interval E-value
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 90-284 5.12e-13

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 68.78  E-value: 5.12e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   90 GGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGD 169
Cdd:NF038329 144 GPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGEAGAKGPAGEKGPQGPRGETGPAGEQGPAGPAGPDGEAGPAGE 223

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  170 AGSDGSPGAP--GSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPitpgaPGPAGPPGPQGPPGAPGQPGHDGQP 247
Cdd:NF038329 224 DGPAGPAGDGqqGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGP-----DGKDGERGPVGPAGKDGQNGKDGLP 298

                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 71996902  248 GTPGPKGPNGNPGAPGADGNPGTPGVAGVAGSGGEKG 284
Cdd:NF038329 299 GKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDG 335
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 107-269 1.70e-12

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 67.24  E-value: 1.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  107 PGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPagdagsDGSPGAPGSDGQPG 186
Cdd:NF038329 122 PGPAGPAGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGKDGE------AGAKGPAGEKGPQG 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  187 AAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPITPGAPGPAGPPGPQGPPGAPGQPGHDGQPGTPGPKGPNGNPGAPGADG 266
Cdd:NF038329 196 PRGETGPAGEQGPAGPAGPDGEAGPAGEDGPAGPAGDGQQGPDGDPGPTGEDGPQGPDGPAGKDGPRGDRGEAGPDGPDG 275


                 ...
gi 71996902  267 NPG 269
Cdd:NF038329 276 KDG 278
Col_cuticle_N smart01088
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 12-64 1.08e-11

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 198156  Cd Length: 53  Bit Score: 59.02  E-value: 1.08e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 71996902     12 FVAYSAVAFSVVAVISVSVTLPMVYNYVHHVKRSMQTEINFCKGSAKDIWTEV 64
Cdd:smart01088   1 LVAYVAVAVSTVAVLSALVTLPSIYNDIQSFQSELLDEMDEFKARADDAWNEM 53
Col_cuticle_N pfam01484
Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is ...
 31-64 4.65e-10

Nematode cuticle collagen N-terminal domain; The function of this domain is unknown. It is found in the N-terminal region of nematode cuticle collagens, see pfam01391. Cuticle is a tough elastic structure secreted by hypodermal cells and is primarily composed of collagen proteins.


Pssm-ID: 460226  Cd Length: 50  Bit Score: 54.39  E-value: 4.65e-10
                          10        20        30
                  ....*....|....*....|....*....|....
gi 71996902    31 TLPMVYNYVHHVKRSMQTEINFCKGSAKDIWTEV 64
Cdd:pfam01484  17 TLPSIYNDIQELQSEVLDEMDEFKARSDDAWNEM 50
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 77-271 5.29e-08

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 53.84  E-value: 5.29e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   77 TARQAGYDAGVNGGGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQG 156
Cdd:PRK07764 585 EAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASD 664

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  157 PAGPPGPPGPAGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPITPGAPGPAGPPGPQGPPG 236
Cdd:PRK07764 665 GGDGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPE 744

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 71996902  237 APGQPGHDGQPGTPGPKGPNGNPGAPGADGNPGTP 271
Cdd:PRK07764 745 PDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 106-219 1.33e-05

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 46.44  E-value: 1.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  106 LPGAAGPAGTPGKPGRPGKAGAPGLPGNPGrppqqpcepitpPPCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSDGQ- 184
Cdd:NF038329 240 DPGPTGEDGPQGPDGPAGKDGPRGDRGEAG------------PDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQn 307

                         90       100       110
                 ....*....|....*....|....*....|....*..
gi 71996902  185 --PGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPIT 219
Cdd:NF038329 308 gkDGLPGKDGKDGQPGKDGLPGKDGKDGQPGKPAPKT 344
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 69-204 2.61e-04

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 42.67  E-value: 2.61e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   69 SIPASRNRTARQAGYDAGVNGGGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPP 148
Cdd:PRK07764 373 GLLARLERLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGG 452

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 71996902  149 PCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNPGAPG 204
Cdd:PRK07764 453 APSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADD 508
Collagen pfam01391
Collagen triple helix repeat (20 copies); Members of this family belong to the collagen ...
 174-215 3.98e-04

Collagen triple helix repeat (20 copies); Members of this family belong to the collagen superfamily. Collagens are generally extracellular structural proteins involved in formation of connective tissue structure. The alignment contains 20 copies of the G-X-Y repeat that forms a triple helix. The first position of the repeat is glycine, the second and third positions can be any residue but are frequently proline and hydroxy-proline. Collagens are post translationally modified by proline hydroxylase to form the hydroxy-proline residues. Defective hydroxylation is the cause of scurvy. Some members of the collagen superfamily are not involved in connective tissue structure but share the same triple helical structure. The family includes bacterial collagen-like triple-helix repeat proteins.


Pssm-ID: 460189 [Multi-domain]  Cd Length: 57  Bit Score: 37.86  E-value: 3.98e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 71996902   174 GSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKS 215
Cdd:pfam01391  10 GPPGPPGPPGPPGPPGPPGPPGEPGPPGPPGPPGPPGPPGAP 51
PRK07003 PRK07003
DNA polymerase III subunit gamma/tau;
79-268 6.45e-04

DNA polymerase III subunit gamma/tau;


Pssm-ID: 235906 [Multi-domain]  Cd Length: 830  Bit Score: 41.37  E-value: 6.45e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   79 RQAGYDAGVNGGGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRPP---QQPCEPITPPPCKPCPQ 155
Cdd:PRK07003 354 RMLAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKaaaAAAATRAEAPPAAPAPP 433

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  156 GPAGPPGPPGPAGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNpGAPGSPGKPgeDGKSEPITPGAPGPAGPPGPQGPP 235
Cdd:PRK07003 434 ATADRGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSA-SAPASDAPP--DAAFEPAPRAAAPSAATPAAVPDA 510

                        170       180       190
                 ....*....|....*....|....*....|...
gi 71996902  236 GAPGQPGHDGQPGTPGPKGPNGNPGAPGADGNP 268
Cdd:PRK07003 511 RAPAAASREDAPAAAAPPAPEARPPTPAAAAPA 543
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 167-271 7.46e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 7.46e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  167 AGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPitPGAPGPAGPPGPQGPPGAPGQPGHDGQ 246
Cdd:NF038329 128 AGPAGEQGPRGDRGETGPAGPAGPPGPQGERGEKGPAGPQGEAGPQGPAGK--DGEAGAKGPAGEKGPQGPRGETGPAGE 205

                         90       100
                 ....*....|....*....|....*
gi 71996902  247 PGTPGPKGPNGNPGAPGADGNPGTP 271
Cdd:NF038329 206 QGPAGPAGPDGEAGPAGEDGPAGPA 230
gly_rich_SclB NF038329
LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like ...
 108-219 8.37e-04

LPXTG-anchored collagen-like adhesin Scl2/SclB; SclB (or Scl2 - streptococcal collagen-like protein 2) is an LPXTG-anchored surface-anchored adhesin with a variable-length region of triple helix-forming collagen-like Gly-Xaa-Xaa repeats.


Pssm-ID: 468478 [Multi-domain]  Cd Length: 440  Bit Score: 40.66  E-value: 8.37e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  108 GAAGPAGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSDGQPGA 187
Cdd:NF038329 260 GPRGDRGEAGPDGPDGKDGERGPVGPAGKDGQNGKDGLPGKDGKDGQNGKDGLPGKDGKDGQPGKDGLPGKDGKDGQPGK 339

                         90       100       110
                 ....*....|....*....|....*....|..
gi 71996902  188 AGDKGPAGPNGNPGAPGSPGKPGEDGKSEPIT 219
Cdd:NF038329 340 PAPKTPEVPQKPDTAPHTPKTPQIPGQSKDVT 371
PRK07764 PRK07764
DNA polymerase III subunits gamma and tau; Validated
 109-282 1.13e-03

DNA polymerase III subunits gamma and tau; Validated


Pssm-ID: 236090 [Multi-domain]  Cd Length: 824  Bit Score: 40.35  E-value: 1.13e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  109 AAGPAGTPGKPGRPGKAGAPGLPGNPGRP--PQQPCEPITPPP-----------CKPCPQGPAGPPGPPGPAGDAGSDGS 175
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPaaPAAPAAPAAPAPagaaaapaeasAAPAPGVAAPEHHPKHVAVPDASDGG 666

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902  176 PGAPGSDGQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKS--EPITPGAPGPAGPPGPQGPPGAPGQPGHDGQPGTPGPK 253
Cdd:PRK07764 667 DGWPAKAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAatPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPD 746

                        170       180
                 ....*....|....*....|....*....
gi 71996902  254 GPNGNPGAPGADGNPGTPGVAGVAGSGGE 282
Cdd:PRK07764 747 DPPDPAGAPAQPPPPPAPAPAAAPAAAPP 775
PRK14959 PRK14959
DNA polymerase III subunits gamma and tau; Provisional
 79-196 2.02e-03

DNA polymerase III subunits gamma and tau; Provisional


Pssm-ID: 184923 [Multi-domain]  Cd Length: 624  Bit Score: 39.66  E-value: 2.02e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   79 RQAGYDAGVNGGGSEASGAPGNCEACCLPGAAGPAGTPGKPGRPGKAGAPGLPGNPGRP-PQQPCE--PITPPPCKPCPQ 155
Cdd:PRK14959 372 RPSGGGASAPSGSAAEGPASGGAATIPTPGTQGPQGTAPAAGMTPSSAAPATPAPSAAPsPRVPWDdaPPAPPRSGIPPR 451

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|..
gi 71996902  156 GPAGPPGPPGPAGDAGSDGS-PGAPGSDGQPGAAGDKGPAGP 196
Cdd:PRK14959 452 PAPRMPEASPVPGAPDSVASaSDAPPTLGDPSDTAEHTPSGP 493
PHA03247 PHA03247
large tegument protein UL36; Provisional
 90-261 2.91e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 39.54  E-value: 2.91e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902    90 GGSEASGAPGNCEACCLPGAAGP--AGTPGKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPP-------CKPCPQGPAGP 160
Cdd:PHA03247 2630 SPSPAANEPDPHPPPTVPPPERPrdDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTvgsltslADPPPPPPTPE 2709

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   161 PGPPGPAGDAGSDGSPGAPGSDGQPGAAGDKGPAGPNGnPGAPGSPGKPGE-DGKSEPITPGAPGPAGPPGPQGPPGAPG 239
Cdd:PHA03247 2710 PAPHALVSATPLPPGPAAARQASPALPAAPAPPAVPAG-PATPGGPARPARpPTTAGPPAPAPPAAPAAGPPRRLTRPAV 2788

                         170       180
                  ....*....|....*....|..
gi 71996902   240 QPGHDGQPGTPGPKGPNGNPGA 261
Cdd:PHA03247 2789 ASLSESRESLPSPWDPADPPAA 2810
PHA03247 PHA03247
large tegument protein UL36; Provisional
 105-271 5.95e-03

large tegument protein UL36; Provisional


Pssm-ID: 223021 [Multi-domain]  Cd Length: 3151  Bit Score: 38.38  E-value: 5.95e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   105 CLPGAAGPAGTP--GKPGRPGKAGAPGLPGNPGRPPQQPCEPITPPPCKPCPQGPAGPPGPPGPAGDAGSDGSPGAPGSD 182
Cdd:PHA03247 2573 PAPRPSEPAVTSraRRPDAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPHPPPTVPPPERP 2652

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71996902   183 GQPGAAGDKGPAGPNGNPGAPGSPGKPGEDGKSEPITPGAPGPAGPPGPQGPPGAPGQPGHDGQPGTPGPKGPNGNPGA- 261
Cdd:PHA03247 2653 RDDPAPGRVSRPRRARRLGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQAs 2732

                         170
                  ....*....|
gi 71996902   262 PGADGNPGTP 271
Cdd:PHA03247 2733 PALPAAPAPP 2742
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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