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Conserved domains on  [gi|71994171|ref|NP_500845|]
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Serpentine Receptor, class D (Delta) [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-295 1.75e-88

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 266.72  E-value: 1.75e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171     5 FVIFHSVLSAIGCVLNSMLCHVAAWKSPTVIKTYSIITVNFAITNLTICGVNFILQMRMVPIEKTMIFVSYGPCQWLTDR 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171    85 TCFNLYSVLVHVYTHTIWLLLISFCYRYYVMIRSEPSKRQVELLLLIIYLPSFIQMILLFFDFTDPLILLDIQQNLVPQY 164
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   165 NFTDLMIFGVADSTSFNAMYSIVHVAVMSTPIVLCIVVLRKKILRKMEFKGVQVNANTRSLQLQLLRALTFQAVIPGFYL 244
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 71994171   245 I-GVASYFVSRLEIYRDPFFEYLIFSAFLFVPVLTPISSFIFVTPYRKWFLK 295
Cdd:pfam10317 241 IpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-295 1.75e-88

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 266.72  E-value: 1.75e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171     5 FVIFHSVLSAIGCVLNSMLCHVAAWKSPTVIKTYSIITVNFAITNLTICGVNFILQMRMVPIEKTMIFVSYGPCQWLTDR 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171    85 TCFNLYSVLVHVYTHTIWLLLISFCYRYYVMIRSEPSKRQVELLLLIIYLPSFIQMILLFFDFTDPLILLDIQQNLVPQY 164
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   165 NFTDLMIFGVADSTSFNAMYSIVHVAVMSTPIVLCIVVLRKKILRKMEFKGVQVNANTRSLQLQLLRALTFQAVIPGFYL 244
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 71994171   245 I-GVASYFVSRLEIYRDPFFEYLIFSAFLFVPVLTPISSFIFVTPYRKWFLK 295
Cdd:pfam10317 241 IpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-295 1.75e-88

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 266.72  E-value: 1.75e-88
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171     5 FVIFHSVLSAIGCVLNSMLCHVAAWKSPTVIKTYSIITVNFAITNLTICGVNFILQMRMVPIEKTMIFVSYGPCQWLTDR 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171    85 TCFNLYSVLVHVYTHTIWLLLISFCYRYYVMIRSEPSKRQVELLLLIIYLPSFIQMILLFFDFTDPLILLDIQQNLVPQY 164
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   165 NFTDLMIFGVADSTSFNAMYSIVHVAVMSTPIVLCIVVLRKKILRKMEFKGVQVNANTRSLQLQLLRALTFQAVIPGFYL 244
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 71994171   245 I-GVASYFVSRLEIYRDPFFEYLIFSAFLFVPVLTPISSFIFVTPYRKWFLK 295
Cdd:pfam10317 241 IpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
8-291 7.82e-08

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 53.02  E-value: 7.82e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171     8 FHSVLSAIGCVL----NSMLCHVAAWKSPTVIKTYSIITVNFAITNLTICGVNFILQMRMVPIEKTM-IFVSYGPCQWLT 82
Cdd:pfam10319   6 AHYYIPKIFGVLsfivNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFvVFVSDGPFFEYS 85
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171    83 DRTcFNLYSVLVHVYTHTIWLLLISFCYRYYVMIRSEPSKRQVE---LLLLIIYLPSFI---QMILLFFDFTDPLILLDI 156
Cdd:pfam10319  86 ELG-QHALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRpwgILISILFFLFHGsvwTAICYFLLRANDEIRDYI 164
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   157 QQNLVPQYNfTDLMIF--------GVADSTSFNAMYSIVHVAVMSTPIVLCIVVLRKKILRKMEFKGVQVNANTRSLQLQ 228
Cdd:pfam10319 165 REDFRETYG-VDSMDInmlgalywEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSKKTKRLQKQ 243
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71994171   229 LLRALTFQAVIPGF--YLIGVASYFVSRLEIYRDPFFEYLIFSAFLFVPVLTPISSFIFVTPYRK 291
Cdd:pfam10319 244 LLKALIVQTIIPICisFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRN 308
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
7-291 9.70e-08

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 52.46  E-value: 9.70e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171     7 IFHSVLSAIGCVLNSMLCHVAAWKSPTVIKTYSIITVNFAITNLTICGVNFILQMRMVPIEKTMIFVSYGPCQWLTDRTC 86
Cdd:pfam10326   3 IIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKSVG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171    87 FNLYSVLVHVYTHTIWLLLISFCYRYYVMIRSEPSKR----QVELLLLIIYLPSFIQMILLFF-----DFTDPLILLDIQ 157
Cdd:pfam10326  83 QILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYfdgkKLILWFLYPLIFGAIWGLLVYFflgpdEETDEYLREELL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   158 QNL---VPQYNFTDLMIFGVADSTS-----FNAMYSIVHVAVMSTPIVLcIVVLRKKILRKMEFKGVQVNANTRSLQLQL 229
Cdd:pfam10326 163 ENYnldIDEVAYVGPVYYPTDENGSkvirwRSLIGLLIMTFIIGISFSI-IIYCGIKMYFKMKKLKSLGSEKTRKLQKQL 241
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   230 LRALTFQAVIPGFYL-IGVASYFVSrleiyrdPFFEY-------LIFSAFLFVPVLTPISSFIFVTPYRK 291
Cdd:pfam10326 242 FKALVIQTLIPTILMyIPVGILFLL-------PLFNIeigflsgIITATIALYPAIDPLPAMFIIKEYRN 304
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
108-295 4.99e-07

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 50.62  E-value: 4.99e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   108 FCYRYYVMIRSEPS---KRQVELLLLIIYLPSFIQMILLFFDFTDPLI-LLDIQQNL--VPQYNFTDLMIFGVADSTSFN 181
Cdd:pfam10318 107 FENRYSILFTNKKRitwKKTRVLYLIFNYIIALLFLIPIYLNIPDQEAaKLKVLKKLpcLPPEFFDNPPVFVLAIDSTYF 186
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71994171   182 AMYSIVHVAVMSTPIVLCIVVLRKKILRKMefkGVQVNANTRSLQLQLLRALTFQAVIPGFYLIGVASYFV-SRLEIYRD 260
Cdd:pfam10318 187 LICIVLLILILIIQILFFVFLTIYYLFKSV---KSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILfSIIFGYYN 263
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 71994171   261 PFFEYLIFSAFLFVPVLTPISSFIFVTPYRKWFLK 295
Cdd:pfam10318 264 QALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLS 298
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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