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Conserved domains on  [gi|922580449|ref|NP_501283|]
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Exocyst complex component 5 [Caenorhabditis elegans]

Protein Classification

exocyst complex component Sec10( domain architecture ID 10538384)

exocyst complex component Sec10 is a component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
91-703 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


:

Pssm-ID: 399988  Cd Length: 704  Bit Score: 566.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449   91 NGEAIDKMKQLDHTMQAVSTKVVHLGDQLESVDQPRSRAHDAHQLMQHFDEFLSDQP-----LNSMIFTDPDKLLESADL 165
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSGPsspleLLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  166 VHKLYSISQEL-NKDKFANVQARIGQRYKVVEDLLIEEFVRSQR--DEKKMAEVAKILSEFKGYSGCVDRYV-------- 234
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRkeDFERMKECAKILQEFNGGASVIQLFVnqhqffid 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  235 -------------------DFLCQSIHPRGDGGEILADCLQLCRTQQPRISAIFPSPHTVMQKLVLNIFTGRMKETITAR 295
Cdd:pfam07393 161 rdvtdevdglddeiweklaDPDQHPSIVEESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  296 LRECKDTDdQEHYLRDLAYLYSSTLKMCKELEKLHIS---PDSAFLSTLTDSIFQRYIATYCSEELKYLNDQCSNLLQRF 372
Cdd:pfam07393 241 LDKAKSIS-QLAYLRSLHSLYSQTLKLVKDLKEFGSTenpDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKF 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  373 YE--------------------------------SKKHVKKQIGGGLHELKRDVAAR--------------LMNVETYGG 406
Cdd:pfam07393 320 TTlheraisaksltnkdkkdfltsfkaslmgsklASKSKLSQINRFLKSSLERTLKRaglfenidssakaaINPIELEGI 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  407 ETFVAEDVAISILQETKNAFGRANQLCDKEELPRHVENIVDVLLKYLYGEHLDYAVE---TGLAGISLAESKTEPPAYFF 483
Cdd:pfam07393 400 DSLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEaalYALSSQEIAEKTGVPDLSFL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  484 SVVAKCTSVILLMIKQFEDPIFPIIKETI-VEPSVAKKWQQSLRSLESKMSLGLERQLNSIVGYVKFLFSEQKKTDFRPD 562
Cdd:pfam07393 480 EVVRVCDEILSLMSVYIKQILIPLLTNSPdIRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILSKQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  563 SQQI--DIRVSPQCQLASRFLANQVAAMELGCDGENLEALQSDLATRLFKFMLTHIQQFTYNSTGAVLLLCDVGELRTLV 640
Cdd:pfam07393 560 EDELtmDVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 922580449  641 SKWRVQNALTQWESLQALTNLLAVLPDQVNETAHSSLLENVDRQLIHDFVRLRTDFRSIKNFQ 703
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDV 702
 
Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
91-703 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


Pssm-ID: 399988  Cd Length: 704  Bit Score: 566.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449   91 NGEAIDKMKQLDHTMQAVSTKVVHLGDQLESVDQPRSRAHDAHQLMQHFDEFLSDQP-----LNSMIFTDPDKLLESADL 165
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSGPsspleLLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  166 VHKLYSISQEL-NKDKFANVQARIGQRYKVVEDLLIEEFVRSQR--DEKKMAEVAKILSEFKGYSGCVDRYV-------- 234
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRkeDFERMKECAKILQEFNGGASVIQLFVnqhqffid 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  235 -------------------DFLCQSIHPRGDGGEILADCLQLCRTQQPRISAIFPSPHTVMQKLVLNIFTGRMKETITAR 295
Cdd:pfam07393 161 rdvtdevdglddeiweklaDPDQHPSIVEESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  296 LRECKDTDdQEHYLRDLAYLYSSTLKMCKELEKLHIS---PDSAFLSTLTDSIFQRYIATYCSEELKYLNDQCSNLLQRF 372
Cdd:pfam07393 241 LDKAKSIS-QLAYLRSLHSLYSQTLKLVKDLKEFGSTenpDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKF 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  373 YE--------------------------------SKKHVKKQIGGGLHELKRDVAAR--------------LMNVETYGG 406
Cdd:pfam07393 320 TTlheraisaksltnkdkkdfltsfkaslmgsklASKSKLSQINRFLKSSLERTLKRaglfenidssakaaINPIELEGI 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  407 ETFVAEDVAISILQETKNAFGRANQLCDKEELPRHVENIVDVLLKYLYGEHLDYAVE---TGLAGISLAESKTEPPAYFF 483
Cdd:pfam07393 400 DSLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEaalYALSSQEIAEKTGVPDLSFL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  484 SVVAKCTSVILLMIKQFEDPIFPIIKETI-VEPSVAKKWQQSLRSLESKMSLGLERQLNSIVGYVKFLFSEQKKTDFRPD 562
Cdd:pfam07393 480 EVVRVCDEILSLMSVYIKQILIPLLTNSPdIRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILSKQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  563 SQQI--DIRVSPQCQLASRFLANQVAAMELGCDGENLEALQSDLATRLFKFMLTHIQQFTYNSTGAVLLLCDVGELRTLV 640
Cdd:pfam07393 560 EDELtmDVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 922580449  641 SKWRVQNALTQWESLQALTNLLAVLPDQVNETAHSSLLENVDRQLIHDFVRLRTDFRSIKNFQ 703
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDV 702
 
Name Accession Description Interval E-value
Sec10 pfam07393
Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 ...
91-703 0e+00

Exocyst complex component Sec10; This family contains the Sec10 component (approximately 650 residues long) of the eukaryotic exocyst complex, which specifically affects the synthesis and delivery of secretory and basolateral plasma membrane proteins.


Pssm-ID: 399988  Cd Length: 704  Bit Score: 566.98  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449   91 NGEAIDKMKQLDHTMQAVSTKVVHLGDQLESVDQPRSRAHDAHQLMQHFDEFLSDQP-----LNSMIFTDPDKLLESADL 165
Cdd:pfam07393   1 LQETVDSFDQLDDKISSVGQKAVKLGDQLEGADRQRQRAIDAAFLIPFYDEFLSSGPsspleLLFKRSKDPDKKLECAQI 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  166 VHKLYSISQEL-NKDKFANVQARIGQRYKVVEDLLIEEFVRSQR--DEKKMAEVAKILSEFKGYSGCVDRYV-------- 234
Cdd:pfam07393  81 ARQLLSIAQKLdPLPKTENTRANIEKYSERLEKELLKEFDAAYRkeDFERMKECAKILQEFNGGASVIQLFVnqhqffid 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  235 -------------------DFLCQSIHPRGDGGEILADCLQLCRTQQPRISAIFPSPHTVMQKLVLNIFTGRMKETITAR 295
Cdd:pfam07393 161 rdvtdevdglddeiweklaDPDQHPSIVEESLQALFSEVVVVVKEEAAIIKRVFPNPEVVMQKFIQRVFAQVIQQRLEAL 240
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  296 LRECKDTDdQEHYLRDLAYLYSSTLKMCKELEKLHIS---PDSAFLSTLTDSIFQRYIATYCSEELKYLNDQCSNLLQRF 372
Cdd:pfam07393 241 LDKAKSIS-QLAYLRSLHSLYSQTLKLVKDLKEFGSTenpDLSAFLDQLTEDLFVPHLDSYLEREKKSLEELYESLLSKF 319
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  373 YE--------------------------------SKKHVKKQIGGGLHELKRDVAAR--------------LMNVETYGG 406
Cdd:pfam07393 320 TTlheraisaksltnkdkkdfltsfkaslmgsklASKSKLSQINRFLKSSLERTLKRaglfenidssakaaINPIELEGI 399
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  407 ETFVAEDVAISILQETKNAFGRANQLCDKEELPRHVENIVDVLLKYLYGEHLDYAVE---TGLAGISLAESKTEPPAYFF 483
Cdd:pfam07393 400 DSLLSIEVALSMLKWAAESLGRALELSSPTELPKNIEALFDLLLRALGHEYIETALEaalYALSSQEIAEKTGVPDLSFL 479
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  484 SVVAKCTSVILLMIKQFEDPIFPIIKETI-VEPSVAKKWQQSLRSLESKMSLGLERQLNSIVGYVKFLFSEQKKTDFRPD 562
Cdd:pfam07393 480 EVVRVCDEILSLMSVYIKQILIPLLTNSPdIRREMVKKKNSFISRLEEKVNAGLQKTIDVLMGWVKYILSKQKKTDFRPK 559
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 922580449  563 SQQI--DIRVSPQCQLASRFLANQVAAMELGCDGENLEALQSDLATRLFKFMLTHIQQFTYNSTGAVLLLCDVGELRTLV 640
Cdd:pfam07393 560 EDELtmDVQPTEACQEVVDFLSSVHSQLVGSLDGSNLEAFLTEIGLRLHRLLLEHLKKFTVNSEGGLILTKDINEYQKFV 639
                         650       660       670       680       690       700
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 922580449  641 SKWRVQNALTQWESLQALTNLLAVLPDQVNETAHSSLLENVDRQLIHDFVRLRTDFRSIKNFQ 703
Cdd:pfam07393 640 KSWGIPELLEKFELLRELGNLFIVQPDLLKELVTEGALANLDRELIREYIQLREDYNQIKLDV 702
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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