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Conserved domains on  [gi|808356118|ref|NP_501325|]
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BBSome complex member bbs-2 [Caenorhabditis elegans]

Protein Classification

BBS2_Mid and BBS2_C domain-containing protein( domain architecture ID 11007001)

protein containing domains BBS2_N, BBS2_Mid, and BBS2_C

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
BBS2_C pfam14782
Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with ...
 298-709 3.63e-153

Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


:

Pssm-ID: 464315  Cd Length: 430  Bit Score: 451.32  E-value: 3.63e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  298 GDESFItVVCLDGKVKGFKIQ----RAQNGSIDKTQQLIREFGQKKHNLMMELSNYEQEEQLADVEKdRDFRIPVDTEVA 373
Cdd:pfam14782  26 GKNQLI-CCSVDGEVRGYLPTgqemKGALVDTSVEQELIRELLQKKQNLLLELKNYEENLKRKKSGE-TDGTIPANTKLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  374 VVFVVNTELQLLSLRVEASHNIPIRGVLIFAEGLFEGESYIWIPPNeyQSRSVIDIPLVIDKDSTNDLHTKVFLGQVDSN 453
Cdd:pfam14782 104 TSLSVNLETGHVELVVSTNNDTIIRAVIIFAEGIFEGESHVVHPNQ--NPSSTLRIPLRPPKDVPVDLHIKVFVGSPGSS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  454 KLMVMENTRILPKFCRFTLLREEYSKFfymPTAYIQFDINSRAAKLSEWVQESFTIDaSLVEMFDEPEGEFKFMGLRPKH 533
Cdd:pfam14782 182 QFHVFELTRQLPKFSMYLLVKNPEPPE---PSSYVTFRINERVQRVVLWLNQNFLLP-EEIEDEDESNLELKFISLRDGS 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  534 EKSLMFKIShseKTCKIYHDKIETMGAIVQSYASFYQIQNMESVAHFPDVFKEADEILEEIDPMTEVRDRLTAELQERQA 613
Cdd:pfam14782 258 PLVISVNAS---GKVTIRTDDMELAGDIIQSLASFLNITDLESTADFPDEMEELREILEKVDELNSVRQKLTAEMADSSN 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  614 AVKEIIIRAEDSIAIDNIPDARKFYIRLKANDAAARQAAQLRWNNQERCVKSLRRLNKIIENCSRLRVGEPGRQIVVSCR 693
Cdd:pfam14782 335 LVKSLIVRAEDARLLGDMKNMRKYYSELMDLNRDLIGEYQKRSNNHNELLSALKEVNQMIQKASRLRVGKAKTQVIAACR 414

                         410
                  ....*....|....*.
gi 808356118  694 SAIADDNKQIITKILQ 709
Cdd:pfam14782 415 NAIKNNNINALFKIIR 430
BBS2_Mid pfam14783
Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association ...
 169-272 9.88e-44

Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


:

Pssm-ID: 405473 [Multi-domain]  Cd Length: 108  Bit Score: 152.81  E-value: 9.88e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  169 TMCLSDYDNDGETELVIGSPDFEIRVFKNDLMRTELMETDEITCLAHVANGCFAYSLNNGTIGTYVLKERQWRIKSKSNV 248
Cdd:pfam14783   1 ALALADFDGDGENELVVGSDDFDIRVFKGDEIVFEFTETEKVTSLATLSGSRFAYALENGTVGVYDKKQRLWRIKSKNQI 80

                          90       100
                  ....*....|....*....|....*...
gi 808356118  249 SKIFNFEEEG----LMVVVWKQGKVDLR 272
Cdd:pfam14783  81 TALAAYDINGdgvkELIVGWSNGKVDAR 108
BBS2_N super family cl20704
Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with ...
 76-131 3.31e-14

Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


The actual alignment was detected with superfamily member pfam14781:

Pssm-ID: 464314  Cd Length: 107  Bit Score: 69.20  E-value: 3.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 808356118   76 LNITETIRCIAAAPFGDGYDC--IIIGTDSSVICYDVHNNLTVFRNDVPDGVSCFVYG 131
Cdd:pfam14781  50 LNINQAVTALTAGRLDPDSGRdiLLVGTQTNLLAYDVENNSDLFYKEVPDGVNAIVFG 107
 
Name Accession Description Interval E-value
BBS2_C pfam14782
Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with ...
 298-709 3.63e-153

Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 464315  Cd Length: 430  Bit Score: 451.32  E-value: 3.63e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  298 GDESFItVVCLDGKVKGFKIQ----RAQNGSIDKTQQLIREFGQKKHNLMMELSNYEQEEQLADVEKdRDFRIPVDTEVA 373
Cdd:pfam14782  26 GKNQLI-CCSVDGEVRGYLPTgqemKGALVDTSVEQELIRELLQKKQNLLLELKNYEENLKRKKSGE-TDGTIPANTKLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  374 VVFVVNTELQLLSLRVEASHNIPIRGVLIFAEGLFEGESYIWIPPNeyQSRSVIDIPLVIDKDSTNDLHTKVFLGQVDSN 453
Cdd:pfam14782 104 TSLSVNLETGHVELVVSTNNDTIIRAVIIFAEGIFEGESHVVHPNQ--NPSSTLRIPLRPPKDVPVDLHIKVFVGSPGSS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  454 KLMVMENTRILPKFCRFTLLREEYSKFfymPTAYIQFDINSRAAKLSEWVQESFTIDaSLVEMFDEPEGEFKFMGLRPKH 533
Cdd:pfam14782 182 QFHVFELTRQLPKFSMYLLVKNPEPPE---PSSYVTFRINERVQRVVLWLNQNFLLP-EEIEDEDESNLELKFISLRDGS 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  534 EKSLMFKIShseKTCKIYHDKIETMGAIVQSYASFYQIQNMESVAHFPDVFKEADEILEEIDPMTEVRDRLTAELQERQA 613
Cdd:pfam14782 258 PLVISVNAS---GKVTIRTDDMELAGDIIQSLASFLNITDLESTADFPDEMEELREILEKVDELNSVRQKLTAEMADSSN 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  614 AVKEIIIRAEDSIAIDNIPDARKFYIRLKANDAAARQAAQLRWNNQERCVKSLRRLNKIIENCSRLRVGEPGRQIVVSCR 693
Cdd:pfam14782 335 LVKSLIVRAEDARLLGDMKNMRKYYSELMDLNRDLIGEYQKRSNNHNELLSALKEVNQMIQKASRLRVGKAKTQVIAACR 414

                         410
                  ....*....|....*.
gi 808356118  694 SAIADDNKQIITKILQ 709
Cdd:pfam14782 415 NAIKNNNINALFKIIR 430
BBS2_Mid pfam14783
Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association ...
 169-272 9.88e-44

Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 405473 [Multi-domain]  Cd Length: 108  Bit Score: 152.81  E-value: 9.88e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  169 TMCLSDYDNDGETELVIGSPDFEIRVFKNDLMRTELMETDEITCLAHVANGCFAYSLNNGTIGTYVLKERQWRIKSKSNV 248
Cdd:pfam14783   1 ALALADFDGDGENELVVGSDDFDIRVFKGDEIVFEFTETEKVTSLATLSGSRFAYALENGTVGVYDKKQRLWRIKSKNQI 80

                          90       100
                  ....*....|....*....|....*...
gi 808356118  249 SKIFNFEEEG----LMVVVWKQGKVDLR 272
Cdd:pfam14783  81 TALAAYDINGdgvkELIVGWSNGKVDAR 108
BBS2_N pfam14781
Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with ...
 76-131 3.31e-14

Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 464314  Cd Length: 107  Bit Score: 69.20  E-value: 3.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 808356118   76 LNITETIRCIAAAPFGDGYDC--IIIGTDSSVICYDVHNNLTVFRNDVPDGVSCFVYG 131
Cdd:pfam14781  50 LNINQAVTALTAGRLDPDSGRdiLLVGTQTNLLAYDVENNSDLFYKEVPDGVNAIVFG 107
 
Name Accession Description Interval E-value
BBS2_C pfam14782
Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with ...
 298-709 3.63e-153

Ciliary BBSome complex subunit 2, C-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 464315  Cd Length: 430  Bit Score: 451.32  E-value: 3.63e-153
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  298 GDESFItVVCLDGKVKGFKIQ----RAQNGSIDKTQQLIREFGQKKHNLMMELSNYEQEEQLADVEKdRDFRIPVDTEVA 373
Cdd:pfam14782  26 GKNQLI-CCSVDGEVRGYLPTgqemKGALVDTSVEQELIRELLQKKQNLLLELKNYEENLKRKKSGE-TDGTIPANTKLQ 103

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  374 VVFVVNTELQLLSLRVEASHNIPIRGVLIFAEGLFEGESYIWIPPNeyQSRSVIDIPLVIDKDSTNDLHTKVFLGQVDSN 453
Cdd:pfam14782 104 TSLSVNLETGHVELVVSTNNDTIIRAVIIFAEGIFEGESHVVHPNQ--NPSSTLRIPLRPPKDVPVDLHIKVFVGSPGSS 181

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  454 KLMVMENTRILPKFCRFTLLREEYSKFfymPTAYIQFDINSRAAKLSEWVQESFTIDaSLVEMFDEPEGEFKFMGLRPKH 533
Cdd:pfam14782 182 QFHVFELTRQLPKFSMYLLVKNPEPPE---PSSYVTFRINERVQRVVLWLNQNFLLP-EEIEDEDESNLELKFISLRDGS 257

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  534 EKSLMFKIShseKTCKIYHDKIETMGAIVQSYASFYQIQNMESVAHFPDVFKEADEILEEIDPMTEVRDRLTAELQERQA 613
Cdd:pfam14782 258 PLVISVNAS---GKVTIRTDDMELAGDIIQSLASFLNITDLESTADFPDEMEELREILEKVDELNSVRQKLTAEMADSSN 334

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  614 AVKEIIIRAEDSIAIDNIPDARKFYIRLKANDAAARQAAQLRWNNQERCVKSLRRLNKIIENCSRLRVGEPGRQIVVSCR 693
Cdd:pfam14782 335 LVKSLIVRAEDARLLGDMKNMRKYYSELMDLNRDLIGEYQKRSNNHNELLSALKEVNQMIQKASRLRVGKAKTQVIAACR 414

                         410
                  ....*....|....*.
gi 808356118  694 SAIADDNKQIITKILQ 709
Cdd:pfam14782 415 NAIKNNNINALFKIIR 430
BBS2_Mid pfam14783
Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association ...
 169-272 9.88e-44

Ciliary BBSome complex subunit 2, middle region; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 405473 [Multi-domain]  Cd Length: 108  Bit Score: 152.81  E-value: 9.88e-44
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 808356118  169 TMCLSDYDNDGETELVIGSPDFEIRVFKNDLMRTELMETDEITCLAHVANGCFAYSLNNGTIGTYVLKERQWRIKSKSNV 248
Cdd:pfam14783   1 ALALADFDGDGENELVVGSDDFDIRVFKGDEIVFEFTETEKVTSLATLSGSRFAYALENGTVGVYDKKQRLWRIKSKNQI 80

                          90       100
                  ....*....|....*....|....*...
gi 808356118  249 SKIFNFEEEG----LMVVVWKQGKVDLR 272
Cdd:pfam14783  81 TALAAYDINGdgvkELIVGWSNGKVDAR 108
BBS2_N pfam14781
Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with ...
 76-131 3.31e-14

Ciliary BBSome complex subunit 2, N-terminal; The BBSome (so-named after the association with Bardet-Biedl syndrome) is a complex of 8 subunits that lies at the base of the flagellar microtubule structure. The precise function of the all the individual components in cilia formation is unclear, however they function to promote loading of cargo to the ciliary axoneme. The primary cilium, a slim microtubule-based organelle that projects from the surface of vertebrate cells has crucial roles in vertebrate development and human genetic diseases. Cilia are required for the response to developmental signals, and evidence is accumulating that the primary cilium is specialized for Hedgehog (Hh) signal transduction. Formation of cilia, in turn, is regulated by other signalling pathways, possibly including the planar cell polarity pathway. The connections between cilia and developmental signalling have begun to clarify the basis of human diseases associated with ciliary dysfunction. BBS2 is one of the three Bardet-Biedl syndrome subunits that is required for leptin receptor signalling in the hypothalamus, and BBS2 and 4 are also required for the localization of somatostatin receptor 3 and melanin-concentrating hormone receptor 1 into neuronal cilia.


Pssm-ID: 464314  Cd Length: 107  Bit Score: 69.20  E-value: 3.31e-14
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 808356118   76 LNITETIRCIAAAPFGDGYDC--IIIGTDSSVICYDVHNNLTVFRNDVPDGVSCFVYG 131
Cdd:pfam14781  50 LNINQAVTALTAGRLDPDSGRdiLLVGTQTNLLAYDVENNSDLFYKEVPDGVNAIVFG 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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