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Conserved domains on  [gi|17542070|ref|NP_502001|]
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Serpentine receptor class delta-7 [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 8-296 2.32e-73

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 227.82  E-value: 2.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070     8 FIGINSILTLLGCFINLFLCYLAIFQSPKAIRTYSLVLINITLTNVGACVTGFLLDQRIIQSGKSMLYVSYGYCSLLGEG 87
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070    88 FCFNIFAAYLHFHTHALWLLFLSFVYRYYVIIRQEPTKKVLQISVVIVYIPSLIQLISMCLQEMNFDELRSLSKEVVPQY 167
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070   168 NLTGLTITGSLDFFTFAPFYCLVHMAIISFLIAIGIHILRKMIINRMVLNGVDVTIRSRNLHAQLLRTLSFKATVPIIYY 247
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 17542070   248 F-GCIFFILGR--IWINPIFEFSIFVPTVIVPVLTPLSAFIHVAPYRDFVSK 296
Cdd:pfam10317 241 IpGVTLYLLSQltGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 8-296 2.32e-73

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 227.82  E-value: 2.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070     8 FIGINSILTLLGCFINLFLCYLAIFQSPKAIRTYSLVLINITLTNVGACVTGFLLDQRIIQSGKSMLYVSYGYCSLLGEG 87
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070    88 FCFNIFAAYLHFHTHALWLLFLSFVYRYYVIIRQEPTKKVLQISVVIVYIPSLIQLISMCLQEMNFDELRSLSKEVVPQY 167
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070   168 NLTGLTITGSLDFFTFAPFYCLVHMAIISFLIAIGIHILRKMIINRMVLNGVDVTIRSRNLHAQLLRTLSFKATVPIIYY 247
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 17542070   248 F-GCIFFILGR--IWINPIFEFSIFVPTVIVPVLTPLSAFIHVAPYRDFVSK 296
Cdd:pfam10317 241 IpGVTLYLLSQltGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 8-296 2.32e-73

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 227.82  E-value: 2.32e-73
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070     8 FIGINSILTLLGCFINLFLCYLAIFQSPKAIRTYSLVLINITLTNVGACVTGFLLDQRIIQSGKSMLYVSYGYCSLLGEG 87
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALISYGPCKYFGPW 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070    88 FCFNIFAAYLHFHTHALWLLFLSFVYRYYVIIRQEPTKKVLQISVVIVYIPSLIQLISMCLQEMNFDELRSLSKEVVPQY 167
Cdd:pfam10317  81 FCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHPNY 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070   168 NLTGLTITGSLDFFTFAPFYCLVHMAIISFLIAIGIHILRKMIINRMVLNGVDVTIRSRNLHAQLLRTLSFKATVPIIYY 247
Cdd:pfam10317 161 NLTDYTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLPLFSY 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|..
gi 17542070   248 F-GCIFFILGR--IWINPIFEFSIFVPTVIVPVLTPLSAFIHVAPYRDFVSK 296
Cdd:pfam10317 241 IpGVTLYLLSQltGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 14-294 2.51e-03

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 38.98  E-value: 2.51e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070    14 ILTLLGCFINLFLCYLAIFQSPKAIRTYSLVLINITLTNVGACVTGFLLDQRIIQSGKSMLYVSYGYCSLLGEGFCFNIF 93
Cdd:pfam10326   7 IGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKSVGQILL 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070    94 AAYLHFHTHALWLLFLSFVYRYYVIIRQEPTK----KVLQISVVIVYIPSLIQLISM-CLQEMNFDELRSLSKEVVPQYN 168
Cdd:pfam10326  87 ALYCGFYGVSISLLAVQFIYRYLALCRPGKLKyfdgKKLILWFLYPLIFGAIWGLLVyFFLGPDEETDEYLREELLENYN 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17542070   169 LT------------GLTITGSLDFFTFAPFYCLVHMAIISFLIAI----GIHILRKMiiNRMVLNGvdvTIRSRNLHAQL 232
Cdd:pfam10326 167 LDidevayvgpvyyPTDENGSKVIRWRSLIGLLIMTFIIGISFSIiiycGIKMYFKM--KKLKSLG---SEKTRKLQKQL 241

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17542070   233 LRTLSFKATVPIIyyfgCIFFILGRIWINPIFEFSIFVPTVIV-------PVLTPLSAFIHVAPYRDFV 294
Cdd:pfam10326 242 FKALVIQTLIPTI----LMYIPVGILFLLPLFNIEIGFLSGIItatialyPAIDPLPAMFIIKEYRNAI 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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