NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|17563354|ref|NP_503203|]
View 

Serpentine Receptor, class H [Caenorhabditis elegans]

Protein Classification

serpentine receptor domain-containing protein( domain architecture ID 27798)

serpentine receptor domain-containing protein which belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Srh super family cl11665
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 29-314 2.99e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


The actual alignment was detected with superfamily member pfam10318:

Pssm-ID: 416353  Cd Length: 302  Bit Score: 77.97  E-value: 2.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354    29 IYPFAHFCVLTKSPKKCGYLKWVVYLHCFWITCEWLSGSFLIDIFDFQPSVTIRVDGLLN--NVLDPVLLYTIYICVdSL 106
Cdd:pfam10318  20 IHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSylGVPTPIQFYIGVTSL-AL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   107 SSTSALILFTSRIF-MIMNMYRQYLSHLRIFCELMIYVLVVIFglwTIPTaIWSIPDQTSEKLKISQD-GQPYPDCLWDD 184
Cdd:pfam10318  99 VGVSIILLFENRYSiLFTNKKRITWKKTRVLYLIFNYIIALLF---LIPI-YLNIPDQEAAKLKVLKKlPCLPPEFFDNP 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   185 NV-VAVFDSGSqseHLVSILTILNWVSCGIAIFVAAkIAFFLLAKRMVNESKATRRMNKKFNQRTILQAFIFLFFSCVPF 263
Cdd:pfam10318 175 PVfVLAIDSTY---FLICIVLLILILIIQILFFVFL-TIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPL 250

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 17563354   264 TVLHLTIIFGLYIPGITYFIDIFSENHPTACVVALFLFYDPYQIYLFKIIG 314
Cdd:pfam10318 251 IYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 29-314 2.99e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 77.97  E-value: 2.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354    29 IYPFAHFCVLTKSPKKCGYLKWVVYLHCFWITCEWLSGSFLIDIFDFQPSVTIRVDGLLN--NVLDPVLLYTIYICVdSL 106
Cdd:pfam10318  20 IHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSylGVPTPIQFYIGVTSL-AL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   107 SSTSALILFTSRIF-MIMNMYRQYLSHLRIFCELMIYVLVVIFglwTIPTaIWSIPDQTSEKLKISQD-GQPYPDCLWDD 184
Cdd:pfam10318  99 VGVSIILLFENRYSiLFTNKKRITWKKTRVLYLIFNYIIALLF---LIPI-YLNIPDQEAAKLKVLKKlPCLPPEFFDNP 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   185 NV-VAVFDSGSqseHLVSILTILNWVSCGIAIFVAAkIAFFLLAKRMVNESKATRRMNKKFNQRTILQAFIFLFFSCVPF 263
Cdd:pfam10318 175 PVfVLAIDSTY---FLICIVLLILILIIQILFFVFL-TIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPL 250

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 17563354   264 TVLHLTIIFGLYIPGITYFIDIFSENHPTACVVALFLFYDPYQIYLFKIIG 314
Cdd:pfam10318 251 IYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Name Accession Description Interval E-value
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 29-314 2.99e-16

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 77.97  E-value: 2.99e-16
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354    29 IYPFAHFCVLTKSPKKCGYLKWVVYLHCFWITCEWLSGSFLIDIFDFQPSVTIRVDGLLN--NVLDPVLLYTIYICVdSL 106
Cdd:pfam10318  20 IHIFGFYCILFKTPKKMKSVKWSLLNLHFWSALLDLSLSFLTIPYIFLPALAGYPLGLLSylGVPTPIQFYIGVTSL-AL 98

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   107 SSTSALILFTSRIF-MIMNMYRQYLSHLRIFCELMIYVLVVIFglwTIPTaIWSIPDQTSEKLKISQD-GQPYPDCLWDD 184
Cdd:pfam10318  99 VGVSIILLFENRYSiLFTNKKRITWKKTRVLYLIFNYIIALLF---LIPI-YLNIPDQEAAKLKVLKKlPCLPPEFFDNP 174

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563354   185 NV-VAVFDSGSqseHLVSILTILNWVSCGIAIFVAAkIAFFLLAKRMVNESKATRRMNKKFNQRTILQAFIFLFFSCVPF 263
Cdd:pfam10318 175 PVfVLAIDSTY---FLICIVLLILILIIQILFFVFL-TIYYLFKSVKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPL 250

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 17563354   264 TVLHLTIIFGLYIPGITYFIDIFSENHPTACVVALFLFYDPYQIYLFKIIG 314
Cdd:pfam10318 251 IYILFSIIFGYYNQALNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH