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Conserved domains on  [gi|17563430|ref|NP_503279|]
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Serpentine Receptor, class J [Caenorhabditis elegans]

Protein Classification

class J serpentine receptor( domain architecture ID 10563403)

class J serpentine receptor (Srj) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
2-307 5.30e-139

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 370974  Cd Length: 310  Bit Score: 395.84  E-value: 5.30e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430     2 IYINWYQKNMPLIFGISSYIVNPLFIYLVLTKSSKQMGKYRFLLIGFAVFDVFYSIAEMLTPIAVINTGYGFVTFITDGP 81
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    82 FSENANY---AVSSRCTFISMSYALLIIHFVYRYLILFYPHQVDKMLQPFGILAMIVLTAGHGASWTWLCEGCLSPNEEI 158
Cdd:pfam10319  81 FFEYSELgqhALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   159 RDMIRPAFLEIHHVNSDNISLLTGQYRNASDFVVYKSLFGIMSLTLFSSYCMCVYIILGYKIMKKMN-ENTNMSSISATL 237
Cdd:pfam10319 161 RDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNkMSVTMSKKTKRL 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   238 NRQLFKALVAQTCIPMFASFLPTVIAWYAPMFLINVTWWNNYICNVALAAFPLIDPAVVIYFIPNYKNTL 307
Cdd:pfam10319 241 QKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
 
Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
2-307 5.30e-139

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 395.84  E-value: 5.30e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430     2 IYINWYQKNMPLIFGISSYIVNPLFIYLVLTKSSKQMGKYRFLLIGFAVFDVFYSIAEMLTPIAVINTGYGFVTFITDGP 81
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    82 FSENANY---AVSSRCTFISMSYALLIIHFVYRYLILFYPHQVDKMLQPFGILAMIVLTAGHGASWTWLCEGCLSPNEEI 158
Cdd:pfam10319  81 FFEYSELgqhALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   159 RDMIRPAFLEIHHVNSDNISLLTGQYRNASDFVVYKSLFGIMSLTLFSSYCMCVYIILGYKIMKKMN-ENTNMSSISATL 237
Cdd:pfam10319 161 RDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNkMSVTMSKKTKRL 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   238 NRQLFKALVAQTCIPMFASFLPTVIAWYAPMFLINVTWWNNYICNVALAAFPLIDPAVVIYFIPNYKNTL 307
Cdd:pfam10319 241 QKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
 
Name Accession Description Interval E-value
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
2-307 5.30e-139

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 395.84  E-value: 5.30e-139
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430     2 IYINWYQKNMPLIFGISSYIVNPLFIYLVLTKSSKQMGKYRFLLIGFAVFDVFYSIAEMLTPIAVINTGYGFVTFITDGP 81
Cdd:pfam10319   1 MYINWAHYYIPKIFGVLSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDGP 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    82 FSENANY---AVSSRCTFISMSYALLIIHFVYRYLILFYPHQVDKMLQPFGILAMIVLTAGHGASWTWLCEGCLSPNEEI 158
Cdd:pfam10319  81 FFEYSELgqhALSARCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEI 160
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   159 RDMIRPAFLEIHHVNSDNISLLTGQYRNASDFVVYKSLFGIMSLTLFSSYCMCVYIILGYKIMKKMN-ENTNMSSISATL 237
Cdd:pfam10319 161 RDYIREDFRETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNkMSVTMSKKTKRL 240
                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   238 NRQLFKALVAQTCIPMFASFLPTVIAWYAPMFLINVTWWNNYICNVALAAFPLIDPAVVIYFIPNYKNTL 307
Cdd:pfam10319 241 QKQLLKALIVQTIIPICISFSPCVLAWYSPIFGIDLGRWNNYLEVIALSAFPFIDPLAIILCLPVYRNRI 310
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
17-308 2.81e-51

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 171.87  E-value: 2.81e-51
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    17 ISSYIVNPLFIYLVLTKSSKQMGKYRFLLIGFAVFDVFYSIAEMLTPIAVINTGYGFVTFITDGPFS---ENANYAVSSR 93
Cdd:pfam10326  10 FLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGlskSVGQILLALY 89
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    94 CTFISMSYALLIIHFVYRYLILFYPHQVdKMLQPFGILAMIVLTAGHGASWTWLCEGCLSPNEEIRDMIRPAFLEIHHVN 173
Cdd:pfam10326  90 CGFYGVSISLLAVQFIYRYLALCRPGKL-KYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELLENYNLD 168
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   174 SDNISLLTGQY----RNASDFVVYKSLFGIMSLTLFSSYCMCVYIILGYKIMKKMNENTNMSSI-SATLNRQLFKALVAQ 248
Cdd:pfam10326 169 IDEVAYVGPVYyptdENGSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEkTRKLQKQLFKALVIQ 248
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   249 TCIPMFASFLPTVIAWYAPMFLINVTWWNNYICnVALAAFPLIDPAVVIYFIPNYKNTLL 308
Cdd:pfam10326 249 TLIPTILMYIPVGILFLLPLFNIEIGFLSGIIT-ATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
14-308 1.02e-20

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 90.30  E-value: 1.02e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    14 IFGISSYIVNPLFIYLVLTKSSKQMGKYRFLLIGFAVFDVFYSIAEMLTPIAVINTG-------YGFVTFItdGPFSENA 86
Cdd:pfam10317   7 IFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGvsmalisYGPCKYF--GPWFCYS 84
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430    87 NYAVssRCTFISMSYALLIIHFVYRYLILFYPHQVDKMLQPFGILAMIVLTAGHGASWTwlcegCLSPNEEIRDMirpaf 166
Cdd:pfam10317  85 GYSL--LQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFL-----SPTDFLPVEAL----- 152
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563430   167 LEIHHVNSD-NISLLTGqyrnASDFVVYKSLFGIMSLTLFSSYCMCVYIILGYKIMKKMNEN-TNMSSISATLNRQLFKA 244
Cdd:pfam10317 153 TKELHPNYNlTDYTVTG----FSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNsVNMSPTTKAQHRQLIKG 228
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 17563430   245 LVAQTCIPMFASFLPTVIAWYAPMFLINVTWWNNYICnVALAAFPLIDPAVVIYFIPNYKNTLL 308
Cdd:pfam10317 229 LTIQALLPLFSYIPGVTLYLLSQLTGTEFLILEYFIF-VLPALPPLLDPLITIYFVTPYRRAIL 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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