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Conserved domains on  [gi|17563534|ref|NP_503851|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-312 1.02e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.02e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534     9 VFTKIQFCATFLINSFLILLTLCYIKEVFGAYKRMVIYFAALGMIFSGLEVTARPYTHNYKASLLFF-SVTTLNLPREVI 87
Cdd:pfam10326   3 IIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSVG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534    88 CLMISLWGGCWIVIVSFIAVQFVYRYLCLFKAQKIKKFEGVRSIFWLIYPMLPGVCYTVAMNFLCAADDYADDYVRGLVS 167
Cdd:pfam10326  83 QILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534   168 ERYSMEISNLPRFPMLPY--AADGS--LRWKSLVYLPICIFLIGIHYIIIIYCCLRMHFSMKKELAKFSTQNQKLQRQFF 243
Cdd:pfam10326 163 ENYNLDIDEVAYVGPVYYptDENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLF 242
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17563534   244 HALIVQTLGPTIFLVIPASPILVLPLlapmFGFDIDLQTGNLFAFVGFYPPFDSIAFMIIVKEYVKVIK 312
Cdd:pfam10326 243 KALVIQTLIPTILMYIPVGILFLLPL----FNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-312 1.02e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.02e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534     9 VFTKIQFCATFLINSFLILLTLCYIKEVFGAYKRMVIYFAALGMIFSGLEVTARPYTHNYKASLLFF-SVTTLNLPREVI 87
Cdd:pfam10326   3 IIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSVG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534    88 CLMISLWGGCWIVIVSFIAVQFVYRYLCLFKAQKIKKFEGVRSIFWLIYPMLPGVCYTVAMNFLCAADDYADDYVRGLVS 167
Cdd:pfam10326  83 QILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534   168 ERYSMEISNLPRFPMLPY--AADGS--LRWKSLVYLPICIFLIGIHYIIIIYCCLRMHFSMKKELAKFSTQNQKLQRQFF 243
Cdd:pfam10326 163 ENYNLDIDEVAYVGPVYYptDENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLF 242
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17563534   244 HALIVQTLGPTIFLVIPASPILVLPLlapmFGFDIDLQTGNLFAFVGFYPPFDSIAFMIIVKEYVKVIK 312
Cdd:pfam10326 243 KALVIQTLIPTILMYIPVGILFLLPL----FNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
9-312 1.02e-97

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 291.28  E-value: 1.02e-97
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534     9 VFTKIQFCATFLINSFLILLTLCYIKEVFGAYKRMVIYFAALGMIFSGLEVTARPYTHNYKASLLFF-SVTTLNLPREVI 87
Cdd:pfam10326   3 IIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFvDLKDLGLSKSVG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534    88 CLMISLWGGCWIVIVSFIAVQFVYRYLCLFKAQKIKKFEGVRSIFWLIYPMLPGVCYTVAMNFLCAADDYADDYVRGLVS 167
Cdd:pfam10326  83 QILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVYFFLGPDEETDEYLREELL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534   168 ERYSMEISNLPRFPMLPY--AADGS--LRWKSLVYLPICIFLIGIHYIIIIYCCLRMHFSMKKELAKFSTQNQKLQRQFF 243
Cdd:pfam10326 163 ENYNLDIDEVAYVGPVYYptDENGSkvIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQLF 242
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 17563534   244 HALIVQTLGPTIFLVIPASPILVLPLlapmFGFDIDLQTGNLFAFVGFYPPFDSIAFMIIVKEYVKVIK 312
Cdd:pfam10326 243 KALVIQTLIPTILMYIPVGILFLLPL----FNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
15-307 1.23e-14

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 73.43  E-value: 1.23e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534    15 FCA-TFLINSFLILLTLCYIKEVFGAYKRMVIYFAALGMIFSGLEVTARPYTHNYKASLLFFSVT-----TLNLPREVIC 88
Cdd:pfam10319  14 FGVlSFIVNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLDIHSYRYCFVVFVSDgpffeYSELGQHALS 93
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534    89 LMISLWGGCWIVIVsfiaVQFVYRYLCLFKAQKI-KKFEGVRSIFWLIYPMLPGVCYTVAMNFLCAADDYADDYVRGLVS 167
Cdd:pfam10319  94 ARCSFISASYAVLL----IHFIYRYLVLFNPQLTrHYFRPWGILISILFFLFHGSVWTAICYFLLRANDEIRDYIREDFR 169
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563534   168 ERYSMEISNLPRFPMLPYAADGSLRWKSLVYLPICIFLIGIHYIIIIYCCLRMHFSMKKELAKFSTQNQKLQRQFFHALI 247
Cdd:pfam10319 170 ETYGVDSMDINMLGALYWEASDETVFRSWLGILLLTVISVYSIILYIVLGYKIMRKLNKMSVTMSKKTKRLQKQLLKALI 249
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17563534   248 VQTLGPTIFLVIPAspilVLPLLAPMFGFDIDLQTGNLFA-FVGFYPPFDSIAFMIIVKEY 307
Cdd:pfam10319 250 VQTIIPICISFSPC----VLAWYSPIFGIDLGRWNNYLEViALSAFPFIDPLAIILCLPVY 306
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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