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Conserved domains on  [gi|17563508|ref|NP_504921|]
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Seven TM Receptor [Caenorhabditis elegans]

Protein Classification

class R serpentine receptor( domain architecture ID 10563422)

class R serpentine receptor, also known as seven TM receptor (Str), belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 7-311 9.65e-92

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402099  Cd Length: 307  Bit Score: 275.87  E-value: 9.65e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508     7 SDNASRVLYIATVVLNCFLIHLTVYHTKQINGAYRSMIVIFALMGLWFTSLDILVRPLMHSYNSCIMYFTLGGTFRGLKR 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508    87 AAEASLLVYSAMYGILIAFLCIQFIYRACVLARPIWSKIFDGWKLIYWLLYCLIIGGLWSYAT-FLCSSDTMTNRYMRNE 165
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVyFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508   166 IRSNYGVDIRNVAYFALMGYNYNGT-EKTLRWNSVSTFSMFVVILLTQYVICLVCGFIMYRRIEGNASSTSNQYQKLQHQ 244
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENgSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563508   245 FFKALIYQLAAPCICFHIPSFFFYIAPFFELEISFRSTIIIYGFNVYPLTDSLILLTVISEYKIALK 311
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 7-311 9.65e-92

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 275.87  E-value: 9.65e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508     7 SDNASRVLYIATVVLNCFLIHLTVYHTKQINGAYRSMIVIFALMGLWFTSLDILVRPLMHSYNSCIMYFTLGGTFRGLKR 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508    87 AAEASLLVYSAMYGILIAFLCIQFIYRACVLARPIWSKIFDGWKLIYWLLYCLIIGGLWSYAT-FLCSSDTMTNRYMRNE 165
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVyFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508   166 IRSNYGVDIRNVAYFALMGYNYNGT-EKTLRWNSVSTFSMFVVILLTQYVICLVCGFIMYRRIEGNASSTSNQYQKLQHQ 244
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENgSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563508   245 FFKALIYQLAAPCICFHIPSFFFYIAPFFELEISFRSTIIIYGFNVYPLTDSLILLTVISEYKIALK 311
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
 
Name Accession Description Interval E-value
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
 7-311 9.65e-92

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 275.87  E-value: 9.65e-92
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508     7 SDNASRVLYIATVVLNCFLIHLTVYHTKQINGAYRSMIVIFALMGLWFTSLDILVRPLMHSYNSCIMYFTLGGTFRGLKR 86
Cdd:pfam10326   1 LHIIQYIGFFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVKPFIHSYNSSFIVFVDLKDLGLSKS 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508    87 AAEASLLVYSAMYGILIAFLCIQFIYRACVLARPIWSKIFDGWKLIYWLLYCLIIGGLWSYAT-FLCSSDTMTNRYMRNE 165
Cdd:pfam10326  81 VGQILLALYCGFYGVSISLLAVQFIYRYLALCRPGKLKYFDGKKLILWFLYPLIFGAIWGLLVyFFLGPDEETDEYLREE 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508   166 IRSNYGVDIRNVAYFALMGYNYNGT-EKTLRWNSVSTFSMFVVILLTQYVICLVCGFIMYRRIEGNASSTSNQYQKLQHQ 244
Cdd:pfam10326 161 LLENYNLDIDEVAYVGPVYYPTDENgSKVIRWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQ 240

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563508   245 FFKALIYQLAAPCICFHIPSFFFYIAPFFELEISFRSTIIIYGFNVYPLTDSLILLTVISEYKIALK 311
Cdd:pfam10326 241 LFKALVIQTLIPTILMYIPVGILFLLPLFNIEIGFLSGIITATIALYPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
 199-274 8.96e-05

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 43.69  E-value: 8.96e-05
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 17563508   199 VSTFSMFVVILLTQYVICLVCGFIMYRRIegNASSTSNQYQKLQHQFFKALIYQLAAPCICFHIPSFFFYIAPFFE 274
Cdd:pfam10318 187 LICIVLLILILIIQILFFVFLTIYYLFKS--VKSSLSKKTRKLQKKFFIALIIQVSIPLIVILIPLIYILFSIIFG 260
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
 13-311 1.59e-04

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 42.92  E-value: 1.59e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508    13 VLYIATVVLNCFLIHLTVYHTKQINGAYRSMIVIFALMGLWFTSLDILVRPLMHSYNSCIMYFtlggtFRGLKRAAEA-- 90
Cdd:pfam10317   7 IFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIPNGVSMALI-----SYGPCKYFGPwf 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508    91 -----SLLVYSAMYGILIAFLCIQFIYRACVLARPIWSKIFdgwkLIYWLLYCLIIGGLWSYatFLCSSDTMTNRYMRNE 165
Cdd:pfam10317  82 cysgySLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLI----LLIIIHYIPSLSQLIVI--FLSPTDFLPVEALTKE 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563508   166 IRSNYGVDIrnvayfalmgYNYNGTEKTLRWNSVSTFSMFVVILLTQYVICLVCGFIMYRRIEGNASSTSNQYQKLQHQF 245
Cdd:pfam10317 156 LHPNYNLTD----------YTVTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQL 225

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563508   246 FKALIYQLAAPCICFhIPSFFFYIAPFFEL-EISFRSTIIIYGFNVYPLTDSLILLTVISEYKIALK 311
Cdd:pfam10317 226 IKGLTIQALLPLFSY-IPGVTLYLLSQLTGtEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAIL 291
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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