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Conserved domains on  [gi|17559922|ref|NP_505109|]
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Methyltransferase FkbM domain-containing protein [Caenorhabditis elegans]

Protein Classification

FkbM family methyltransferase( domain architecture ID 10523603)

FkbM family methyltransferase is a class I SAM-dependent methyltransferase that catalyzes the methylation of one or more specific substrates using S-adenosyl-L-methionine (SAM or AdoMet) as the methyl donor

CATH:  2.20.25.110
EC:  2.1.1.-
Gene Ontology:  GO:1904047|GO:0008168
PubMed:  12504684|23180741|12826405
SCOP:  3000118

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Methyltransf_21 pfam05050
Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to ...
 141-245 6.61e-09

Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to be a methyltransferase.


:

Pssm-ID: 428282  Cd Length: 170  Bit Score: 54.11  E-value: 6.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559922   141 SFGKFFNMAVGDRNGSFRSYVLE-EIYRYQEVLTIDLVTFIKANvRQQTIDQLMIDIEHAEYPVFpfieekgQLEDNGII 219
Cdd:pfam05050  63 GGGGYLLFAVGDPQGASTSSVLGgEEAKYIEVETVTLDSFLEEI-KKSDIDLLKIDVEGAELEVL-------EGAEKTLK 134

                          90       100       110
                  ....*....|....*....|....*....|..
gi 17559922   220 VCQIN---IEIHSPIDEDRETFAN---FLRKN 245
Cdd:pfam05050 135 RCQPNiivIEVHFFHYFGGPLFDEirqFLREC 166
 
Name Accession Description Interval E-value
Methyltransf_21 pfam05050
Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to ...
 141-245 6.61e-09

Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to be a methyltransferase.


Pssm-ID: 428282  Cd Length: 170  Bit Score: 54.11  E-value: 6.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559922   141 SFGKFFNMAVGDRNGSFRSYVLE-EIYRYQEVLTIDLVTFIKANvRQQTIDQLMIDIEHAEYPVFpfieekgQLEDNGII 219
Cdd:pfam05050  63 GGGGYLLFAVGDPQGASTSSVLGgEEAKYIEVETVTLDSFLEEI-KKSDIDLLKIDVEGAELEVL-------EGAEKTLK 134

                          90       100       110
                  ....*....|....*....|....*....|..
gi 17559922   220 VCQIN---IEIHSPIDEDRETFAN---FLRKN 245
Cdd:pfam05050 135 RCQPNiivIEVHFFHYFGGPLFDEirqFLREC 166
 
Name Accession Description Interval E-value
Methyltransf_21 pfam05050
Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to ...
 141-245 6.61e-09

Methyltransferase FkbM domain; This family has members from bacteria to human, and appears to be a methyltransferase.


Pssm-ID: 428282  Cd Length: 170  Bit Score: 54.11  E-value: 6.61e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17559922   141 SFGKFFNMAVGDRNGSFRSYVLE-EIYRYQEVLTIDLVTFIKANvRQQTIDQLMIDIEHAEYPVFpfieekgQLEDNGII 219
Cdd:pfam05050  63 GGGGYLLFAVGDPQGASTSSVLGgEEAKYIEVETVTLDSFLEEI-KKSDIDLLKIDVEGAELEVL-------EGAEKTLK 134

                          90       100       110
                  ....*....|....*....|....*....|..
gi 17559922   220 VCQIN---IEIHSPIDEDRETFAN---FLRKN 245
Cdd:pfam05050 135 RCQPNiivIEVHFFHYFGGPLFDEirqFLREC 166
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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