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Conserved domains on  [gi|17562934|ref|NP_506025|]
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Kynurenine 3-monooxygenase [Caenorhabditis elegans]

Protein Classification

FAD-dependent oxidoreductase( domain architecture ID 11428987)

FAD-dependent oxidoreductase catalyzes the transfer of electrons from one molecule, the electron donor or reductant, to another molecule, the electron acceptor or oxidant

CATH:  3.50.50.60
EC:  1.-.-.-
Gene Ontology:  GO:0071949|GO:0016491

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
1-376 9.65e-38

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


:

Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 140.07  E-value: 9.65e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   1 MPSVAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRTmkhvQGRSInlALSQRGKSALEAVGLKEYIVNQGVPLYARLI 80
Cdd:COG0654   3 RTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRP----DGRGI--ALSPRSLELLRRLGLWDRLLARGAPIRGIRV 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  81 HNK-DGKTYSRQPYGKPG-EHIVSINRRHLNEVMITQAEKSpNVKFFFEHKVKNVDYDKKQLVVQCTSQPSkiptfgnks 158
Cdd:COG0654  77 RDGsDGRVLARFDAAETGlPAGLVVPRADLERALLEAARAL-GVELRFGTEVTGLEQDADGVTVTLADGRT--------- 146
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 159 ppqehaefhVEADLILACDGAYSAVRRsLMTIPrfdfsqeyiehgyvelnimannnefafeenvFHLWPRGHFTLIAlan 238
Cdd:COG0654 147 ---------LRADLVVGADGARSAVRR-LLGIG-------------------------------FTGRDYPQRALWA--- 182
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 239 rdktftvtifapfsefekhmstseDVLSFFEENFPDAFLLLGKEHIADtfnRVKPQPLVSIKCSPHSfFDNLVLMGDAAH 318
Cdd:COG0654 183 ------------------------GVRTELRARLAAAGPRLGELLELS---PRSAFPLRRRRAERWR-RGRVVLLGDAAH 234
                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 319 AMVPFYGQGMNCGFEDCLVFSETLEEY--GNDIAKAVKVYSDGRVNDAHSINDLAMYNYE 376
Cdd:COG0654 235 TMHPLGGQGANLALRDAAALAWKLAAAlrGRDDEAALARYERERRPRAARVQRAADALGR 294
 
Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
1-376 9.65e-38

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 140.07  E-value: 9.65e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   1 MPSVAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRTmkhvQGRSInlALSQRGKSALEAVGLKEYIVNQGVPLYARLI 80
Cdd:COG0654   3 RTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRP----DGRGI--ALSPRSLELLRRLGLWDRLLARGAPIRGIRV 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  81 HNK-DGKTYSRQPYGKPG-EHIVSINRRHLNEVMITQAEKSpNVKFFFEHKVKNVDYDKKQLVVQCTSQPSkiptfgnks 158
Cdd:COG0654  77 RDGsDGRVLARFDAAETGlPAGLVVPRADLERALLEAARAL-GVELRFGTEVTGLEQDADGVTVTLADGRT--------- 146
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 159 ppqehaefhVEADLILACDGAYSAVRRsLMTIPrfdfsqeyiehgyvelnimannnefafeenvFHLWPRGHFTLIAlan 238
Cdd:COG0654 147 ---------LRADLVVGADGARSAVRR-LLGIG-------------------------------FTGRDYPQRALWA--- 182
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 239 rdktftvtifapfsefekhmstseDVLSFFEENFPDAFLLLGKEHIADtfnRVKPQPLVSIKCSPHSfFDNLVLMGDAAH 318
Cdd:COG0654 183 ------------------------GVRTELRARLAAAGPRLGELLELS---PRSAFPLRRRRAERWR-RGRVVLLGDAAH 234
                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 319 AMVPFYGQGMNCGFEDCLVFSETLEEY--GNDIAKAVKVYSDGRVNDAHSINDLAMYNYE 376
Cdd:COG0654 235 TMHPLGGQGANLALRDAAALAWKLAAAlrGRDDEAALARYERERRPRAARVQRAADALGR 294
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
4-350 5.37e-18

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 85.33  E-value: 5.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934     4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRkdiRTMKHVQ----GRSInlALSQRGKSALEAVGLKEYIVNQGV-PLyaR 78
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEAT---PLPAPADpgfdNRVS--ALSAASIRLLEKLGVWDKIEPARAqPI--R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    79 LIHNKDGKT-----YSRQPYGKP--GeHIVSiNRRhLNEVMITQAEKSPNVKFFFEHKVKNVdydkkqlvvQCTSQPSKI 151
Cdd:TIGR01988  75 DIHVSDGGSfgalrFDADEIGLEalG-YVVE-NRV-LQQALWERLQELPNVTLLCPARVVEL---------PRHSDHVEL 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   152 pTFGNKSPpqehaefhVEADLILACDGAYSAVRRsLMTIP--RFDFSQeyieHGYV-ELNIMANNNEFAFEenvfHLWPR 228
Cdd:TIGR01988 143 -TLDDGQQ--------LRARLLVGADGANSKVRQ-LAGIPttGWDYGQ----SAVVaNVKHERPHQGTAWE----RFTPT 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   229 GHFTLIALAnrDKTFTVTIFAPFSEFEKHMSTSEDVLSFF-EENFP---DAFLLLGKEHiadTFnrvkpqPLVSIKcsPH 304
Cdd:TIGR01988 205 GPLALLPLP--DNRSSLVWTLPPEEAERLLALSDEEFLAElQRAFGsrlGAITLVGERH---AF------PLSLTH--AK 271
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 17562934   305 SFFDN-LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEE---YGNDIA 350
Cdd:TIGR01988 272 RYVAPrLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDarrRGEDIG 321
PRK06753 PRK06753
hypothetical protein; Provisional
4-361 4.00e-16

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 79.73  E-value: 4.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRtmkhVQGRSINLAlsQRGKSALEAVGLKEYIVNQGVPLYARLIHNK 83
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKNESVK----EVGAGIGIG--DNVIKKLGNHDLAKGIKNAGQILSTMNLLDD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   84 DGKTYSRQpYGKPGEHIVSINRRHLNEVMITQAEKSpnvKFFFEHKVKNVDYDKKQLVVqctsqpskipTFGNksppQEH 163
Cdd:PRK06753  77 KGTLLNKV-KLKSNTLNVTLHRQTLIDIIKSYVKED---AIFTGKEVTKIENETDKVTI----------HFAD----GES 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  164 AEFhveaDLILACDGAYSAVRRSLmtiprfDFSQEYIEHGYVELNIMANNNEFAFEENVFHLW-PRGHFTLIALANRDKT 242
Cdd:PRK06753 139 EAF----DLCIGADGIHSKVRQSV------NADSKVRYQGYTCFRGLIDDIDLKLPDCAKEYWgTKGRFGIVPLLNNQAY 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  243 FTVTIFAPFSEFEKHMSTSEDVLSFFEeNFPDAflllgkehIADTFNRVKPQPL-----VSIKCSPHSFFDNLVLMGDAA 317
Cdd:PRK06753 209 WFITINAKERDPKYSSFGKPHLQAYFN-HYPNE--------VREILDKQSETGIlhhdiYDLKPLKSFVYGRIVLLGDAA 279
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 17562934  318 HAMVPFYGQGMNCGFEDCLVFSETLEEYgnDIAKAVKVYSDGRV 361
Cdd:PRK06753 280 HATTPNMGQGAGQAMEDAIVLANCLNAY--DFEKALQRYDKIRV 321
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
4-334 1.48e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 59.26  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934     4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDirtmKHVQGRSinLALSQRGKSALEAVGLKEYIVNQGVPlyarlIHNK 83
Cdd:pfam01494   4 VLIVGGGPAGLMLALLLARAGVRVVLVERHAT----TSVLPRA--HGLNQRTMELLRQAGLEDRILAEGVP-----HEGM 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    84 DGKTYSRQPYGK-----PGEHIVSINRRHLNEVMITQAEKSPnVKFFFEHKVKNV--DYDKKQLVVqctsqpskipTFGN 156
Cdd:pfam01494  73 GLAFYNTRRRADldfltSPPRVTVYPQTELEPILVEHAEARG-AQVRFGTEVLSLeqDGDGVTAVV----------RDRR 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   157 kspPQEHAEFHveADLILACDGAYSAVRRSLmtiprfdfSQEYIEHGYVELNIMANNNE-----FAFEENVFHLWPRG-H 230
Cdd:pfam01494 142 ---DGEEYTVR--AKYLVGCDGGRSPVRKTL--------GIEFEGFEGVPFGSLDVLFDapdlsDPVERAFVHYLIYApH 208
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   231 FTLIALANRDKTFTVTIFAPFSEFEKHMSTSEDvlsFFEENFPDAFLLLGKEHIADT-FNRVKPQPLVSIKCSPHsFFDN 309
Cdd:pfam01494 209 SRGFMVGPWRSAGRERYYVQVPWDEEVEERPEE---FTDEELKQRLRSIVGIDLALVeILWKSIWGVASRVATRY-RKGR 284
                         330       340
                  ....*....|....*....|....*
gi 17562934   310 LVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:pfam01494 285 VFLAGDAAHIHPPTGGQGLNTAIQD 309
 
Name Accession Description Interval E-value
UbiH COG0654
2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme ...
1-376 9.65e-38

2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme transport and metabolism, Energy production and conversion]; 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 440419 [Multi-domain]  Cd Length: 326  Bit Score: 140.07  E-value: 9.65e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   1 MPSVAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRTmkhvQGRSInlALSQRGKSALEAVGLKEYIVNQGVPLYARLI 80
Cdd:COG0654   3 RTDVLIVGGGPAGLALALALARAGIRVTVVERAPPPRP----DGRGI--ALSPRSLELLRRLGLWDRLLARGAPIRGIRV 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  81 HNK-DGKTYSRQPYGKPG-EHIVSINRRHLNEVMITQAEKSpNVKFFFEHKVKNVDYDKKQLVVQCTSQPSkiptfgnks 158
Cdd:COG0654  77 RDGsDGRVLARFDAAETGlPAGLVVPRADLERALLEAARAL-GVELRFGTEVTGLEQDADGVTVTLADGRT--------- 146
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 159 ppqehaefhVEADLILACDGAYSAVRRsLMTIPrfdfsqeyiehgyvelnimannnefafeenvFHLWPRGHFTLIAlan 238
Cdd:COG0654 147 ---------LRADLVVGADGARSAVRR-LLGIG-------------------------------FTGRDYPQRALWA--- 182
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 239 rdktftvtifapfsefekhmstseDVLSFFEENFPDAFLLLGKEHIADtfnRVKPQPLVSIKCSPHSfFDNLVLMGDAAH 318
Cdd:COG0654 183 ------------------------GVRTELRARLAAAGPRLGELLELS---PRSAFPLRRRRAERWR-RGRVVLLGDAAH 234
                       330       340       350       360       370       380
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 319 AMVPFYGQGMNCGFEDCLVFSETLEEY--GNDIAKAVKVYSDGRVNDAHSINDLAMYNYE 376
Cdd:COG0654 235 TMHPLGGQGANLALRDAAALAWKLAAAlrGRDDEAALARYERERRPRAARVQRAADALGR 294
Ubi-OHases TIGR01988
Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a ...
4-350 5.37e-18

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family; This model represents a family of FAD-dependent hydroxylases (monooxygenases) which are all believed to act in the aerobic ubiquinone biosynthesis pathway. A separate set of hydroxylases, as yet undiscovered, are believed to be active under anaerobic conditions. In E. coli three enzyme activities have been described, UbiB (which acts first at position 6, see TIGR01982), UbiH (which acts at position 4) and UbiF (which acts at position 5). UbiH and UbiF are similar to one another and form the basis of this subfamily. Interestingly, E. coli contains another hydroxylase gene, called visC, that is highly similar to UbiF, adjacent to UbiH and, when mutated, results in a phenotype similar to that of UbiH (which has also been named visB). Several other species appear to have three homologs in this family, although they assort themselves differently on phylogenetic trees (e.g. Xylella and Mesorhizobium) making it difficult to ascribe a specific activity to each one. Eukaryotes appear to have only a single homolog in this subfamily (COQ6) which complements UbiH, but also possess a non-orthologous gene, COQ7 which complements UbiF. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone]


Pssm-ID: 273913 [Multi-domain]  Cd Length: 385  Bit Score: 85.33  E-value: 5.37e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934     4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRkdiRTMKHVQ----GRSInlALSQRGKSALEAVGLKEYIVNQGV-PLyaR 78
Cdd:TIGR01988   2 IVIVGGGMVGLALALALARSGLKVALIEAT---PLPAPADpgfdNRVS--ALSAASIRLLEKLGVWDKIEPARAqPI--R 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    79 LIHNKDGKT-----YSRQPYGKP--GeHIVSiNRRhLNEVMITQAEKSPNVKFFFEHKVKNVdydkkqlvvQCTSQPSKI 151
Cdd:TIGR01988  75 DIHVSDGGSfgalrFDADEIGLEalG-YVVE-NRV-LQQALWERLQELPNVTLLCPARVVEL---------PRHSDHVEL 142
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   152 pTFGNKSPpqehaefhVEADLILACDGAYSAVRRsLMTIP--RFDFSQeyieHGYV-ELNIMANNNEFAFEenvfHLWPR 228
Cdd:TIGR01988 143 -TLDDGQQ--------LRARLLVGADGANSKVRQ-LAGIPttGWDYGQ----SAVVaNVKHERPHQGTAWE----RFTPT 204
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   229 GHFTLIALAnrDKTFTVTIFAPFSEFEKHMSTSEDVLSFF-EENFP---DAFLLLGKEHiadTFnrvkpqPLVSIKcsPH 304
Cdd:TIGR01988 205 GPLALLPLP--DNRSSLVWTLPPEEAERLLALSDEEFLAElQRAFGsrlGAITLVGERH---AF------PLSLTH--AK 271
                         330       340       350       360       370
                  ....*....|....*....|....*....|....*....|....*....|
gi 17562934   305 SFFDN-LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEE---YGNDIA 350
Cdd:TIGR01988 272 RYVAPrLALIGDAAHTIHPLAGQGLNLGLRDVAALAEVLEDarrRGEDIG 321
PRK06753 PRK06753
hypothetical protein; Provisional
4-361 4.00e-16

hypothetical protein; Provisional


Pssm-ID: 168661 [Multi-domain]  Cd Length: 373  Bit Score: 79.73  E-value: 4.00e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRtmkhVQGRSINLAlsQRGKSALEAVGLKEYIVNQGVPLYARLIHNK 83
Cdd:PRK06753   3 IAIIGAGIGGLTAAALLQEQGHEVKVFEKNESVK----EVGAGIGIG--DNVIKKLGNHDLAKGIKNAGQILSTMNLLDD 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   84 DGKTYSRQpYGKPGEHIVSINRRHLNEVMITQAEKSpnvKFFFEHKVKNVDYDKKQLVVqctsqpskipTFGNksppQEH 163
Cdd:PRK06753  77 KGTLLNKV-KLKSNTLNVTLHRQTLIDIIKSYVKED---AIFTGKEVTKIENETDKVTI----------HFAD----GES 138
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  164 AEFhveaDLILACDGAYSAVRRSLmtiprfDFSQEYIEHGYVELNIMANNNEFAFEENVFHLW-PRGHFTLIALANRDKT 242
Cdd:PRK06753 139 EAF----DLCIGADGIHSKVRQSV------NADSKVRYQGYTCFRGLIDDIDLKLPDCAKEYWgTKGRFGIVPLLNNQAY 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  243 FTVTIFAPFSEFEKHMSTSEDVLSFFEeNFPDAflllgkehIADTFNRVKPQPL-----VSIKCSPHSFFDNLVLMGDAA 317
Cdd:PRK06753 209 WFITINAKERDPKYSSFGKPHLQAYFN-HYPNE--------VREILDKQSETGIlhhdiYDLKPLKSFVYGRIVLLGDAA 279
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....
gi 17562934  318 HAMVPFYGQGMNCGFEDCLVFSETLEEYgnDIAKAVKVYSDGRV 361
Cdd:PRK06753 280 HATTPNMGQGAGQAMEDAIVLANCLNAY--DFEKALQRYDKIRV 321
FixC COG0644
Dehydrogenase (flavoprotein) [Energy production and conversion];
9-329 9.62e-15

Dehydrogenase (flavoprotein) [Energy production and conversion];


Pssm-ID: 440409 [Multi-domain]  Cd Length: 281  Bit Score: 74.23  E-value: 9.62e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   9 AGLVGALNACFFAQKGWDVSVYEfRKDIRTMKHVQGrsinlALSQRGKSALEAVGLKEYIVNqgvPLYARLIHNKDGKty 88
Cdd:COG0644   1 AGPAGSAAARRLARAGLSVLLLE-KGSFPGDKICGG-----GLLPRALEELEPLGLDEPLER---PVRGARFYSPGGK-- 69
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  89 sRQPYGKPGEHIVSINRRHLNEVMITQAEKSpNVKFFFEHKVKNVDYDKKQLVVQCTSqpskiptfgnksppqehaEFHV 168
Cdd:COG0644  70 -SVELPPGRGGGYVVDRARFDRWLAEQAEEA-GAEVRTGTRVTDVLRDDGRVVVRTGD------------------GEEI 129
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 169 EADLILACDGAYSAVRRSLMTIPRFDFSQEYIehgyvelnimannnefafeenvfhlwprghftlialanrdktftVTIF 248
Cdd:COG0644 130 RADYVVDADGARSLLARKLGLKRRSDEPQDYA--------------------------------------------LAIK 165
                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934 249 APFSEFEKHMSTSEDVLSFFEENFPD--AFLL-LGKEHIAdtfnrvkpqplVSIKCS---PHSFFDNLVLMGDAAHAMVP 322
Cdd:COG0644 166 EHWELPPLEGVDPGAVEFFFGEGAPGgyGWVFpLGDGRVS-----------VGIPLGgprPRLVGDGVLLVGDAAGFVDP 234

                ....*..
gi 17562934 323 FYGQGMN 329
Cdd:COG0644 235 LTGEGIH 241
PRK07364 PRK07364
FAD-dependent hydroxylase;
4-349 6.70e-10

FAD-dependent hydroxylase;


Pssm-ID: 236001 [Multi-domain]  Cd Length: 415  Bit Score: 60.80  E-value: 6.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEfrkdIRTMKHVQGRSINLALSQRGKSALEAVGLKEYIVNQGVPLyaRLIHNK 83
Cdd:PRK07364  21 VAIVGGGIVGLTLAAALKDSGLRIALIE----AQPAEAAAAKGQAYALSLLSARIFEGIGVWEKILPQIGKF--RQIRLS 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   84 DGKTYSRQPY----------GKPGEHIVsinrrhLNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQLVVQCtsqpskipt 153
Cdd:PRK07364  95 DADYPGVVKFqptdlgtealGYVGEHQV------LLEALQEFLQSCPNITWLCPAEVVSVEYQQDAATVTL--------- 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  154 fgnKSPPQEHaefHVEADLILACDGAYSAVrRSLMTIPR--FDFSQE----YIEHgyvelniMANNNEFAFEEnvfhLWP 227
Cdd:PRK07364 160 ---EIEGKQQ---TLQSKLVVAADGARSPI-RQAAGIKTkgWKYWQScvtaTVKH-------EAPHNDIAYER----FWP 221
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  228 RGHFTLIALANRDKTFTVTifAPFSEFEKHMSTSE-DVLSFFEENFPDaflLLGK-EHIADTFnrVKPqplVSIKCSPHS 305
Cdd:PRK07364 222 SGPFAILPLPGNRCQIVWT--APHAQAKALLALPEaEFLAELQQRYGD---QLGKlELLGDRF--LFP---VQLMQSDRY 291
                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*..
gi 17562934  306 FFDNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEE---YGNDI 349
Cdd:PRK07364 292 VQHRLALVGDAAHCCHPVGGQGLNLGIRDAAALAQVLQTahqRGEDI 338
PRK08163 PRK08163
3-hydroxybenzoate 6-monooxygenase;
2-361 1.05e-09

3-hydroxybenzoate 6-monooxygenase;


Pssm-ID: 181262 [Multi-domain]  Cd Length: 396  Bit Score: 60.05  E-value: 1.05e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    2 PSVAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRTMkhvqGRSINLAlsQRGKSALEAVGLKEYIVNQGV-PLYARLI 80
Cdd:PRK08163   5 TPVLIVGGGIGGLAAALALARQGIKVKLLEQAAEIGEI----GAGIQLG--PNAFSALDALGVGEAARQRAVfTDHLTMM 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   81 HNKDGKTYSRQPYGKP-----GEHIVSINRRHLNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQLVVQctsqpskiptfg 155
Cdd:PRK08163  79 DAVDAEEVVRIPTGQAfrarfGNPYAVIHRADIHLSLLEAVLDHPLVEFRTSTHVVGIEQDGDGVTVF------------ 146
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  156 nksppQEHAEFHvEADLILACDGAYSAVRRSLM--------------TIPRFDFSQEYiehgyvelnimannnefafEEN 221
Cdd:PRK08163 147 -----DQQGNRW-TGDALIGCDGVKSVVRQSLVgdaprvtghvvyraVIDVDDMPEDL-------------------RIN 201
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  222 VFHLW--PRGH-----------FTLIALANRDKtftvtifapFSEFEKHMSTSEDVLSFFEENFPDAFLLLGK------- 281
Cdd:PRK08163 202 APVLWagPHCHlvhyplrggeqYNLVVTFHSRE---------QEEWGVKDGSKEEVLSYFEGIHPRPRQMLDKptswkrw 272
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  282 -----EHIAD-TFNRVkpqplvsikcsphsffdnlVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGNDIAKAVKV 355
Cdd:PRK08163 273 atadrEPVAKwSTGRV-------------------TLLGDAAHPMTQYMAQGACMALEDAVTLGKALEGCDGDAEAAFAL 333

                 ....*.
gi 17562934  356 YSDGRV 361
Cdd:PRK08163 334 YESVRI 339
FAD_binding_3 pfam01494
FAD binding domain; This domain is involved in FAD binding in a number of enzymes.
4-334 1.48e-09

FAD binding domain; This domain is involved in FAD binding in a number of enzymes.


Pssm-ID: 396193 [Multi-domain]  Cd Length: 348  Bit Score: 59.26  E-value: 1.48e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934     4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDirtmKHVQGRSinLALSQRGKSALEAVGLKEYIVNQGVPlyarlIHNK 83
Cdd:pfam01494   4 VLIVGGGPAGLMLALLLARAGVRVVLVERHAT----TSVLPRA--HGLNQRTMELLRQAGLEDRILAEGVP-----HEGM 72
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    84 DGKTYSRQPYGK-----PGEHIVSINRRHLNEVMITQAEKSPnVKFFFEHKVKNV--DYDKKQLVVqctsqpskipTFGN 156
Cdd:pfam01494  73 GLAFYNTRRRADldfltSPPRVTVYPQTELEPILVEHAEARG-AQVRFGTEVLSLeqDGDGVTAVV----------RDRR 141
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   157 kspPQEHAEFHveADLILACDGAYSAVRRSLmtiprfdfSQEYIEHGYVELNIMANNNE-----FAFEENVFHLWPRG-H 230
Cdd:pfam01494 142 ---DGEEYTVR--AKYLVGCDGGRSPVRKTL--------GIEFEGFEGVPFGSLDVLFDapdlsDPVERAFVHYLIYApH 208
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   231 FTLIALANRDKTFTVTIFAPFSEFEKHMSTSEDvlsFFEENFPDAFLLLGKEHIADT-FNRVKPQPLVSIKCSPHsFFDN 309
Cdd:pfam01494 209 SRGFMVGPWRSAGRERYYVQVPWDEEVEERPEE---FTDEELKQRLRSIVGIDLALVeILWKSIWGVASRVATRY-RKGR 284
                         330       340
                  ....*....|....*....|....*
gi 17562934   310 LVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:pfam01494 285 VFLAGDAAHIHPPTGGQGLNTAIQD 309
mhpA PRK06183
bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;
4-334 6.66e-09

bifunctional 3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid hydroxylase;


Pssm-ID: 235727 [Multi-domain]  Cd Length: 500  Bit Score: 57.99  E-value: 6.66e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIrtmkhvqgrsINL--ALSQRGKSA--LEAVGLKEYIVNQGVPLYARL 79
Cdd:PRK06183  13 VVIVGAGPVGLTLANLLGQYGVRVLVLERWPTL----------YDLprAVGIDDEALrvLQAIGLADEVLPHTTPNHGMR 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   80 IHNKDGKTY------SRQPYGKPGEhivsiNRRH---LNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQLVVQCTsqpsk 150
Cdd:PRK06183  83 FLDAKGRCLaeiarpSTGEFGWPRR-----NAFHqplLEAVLRAGLARFPHVRVRFGHEVTALTQDDDGVTVTLT----- 152
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  151 iptfgnkspPQEHAEFHVEADLILACDGAYSAVRRSlMTIPRFDFSQEyieHGYVELNIMANNNEFAFEENVFHLWPRGH 230
Cdd:PRK06183 153 ---------DADGQRETVRARYVVGCDGANSFVRRT-LGVPFEDLTFP---ERWLVVDVLIANDPLGGPHTYQYCDPARP 219
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  231 FTLIALANRDKTFTVTIFApfSEfekhmsTSEDVLSffeenfpDAFL--LLGKEHIAD-----------TFNRVKPQPLV 297
Cdd:PRK06183 220 YTSVRLPHGRRRWEFMLLP--GE------TEEQLAS-------PENVwrLLAPWGPTPddaelirhavyTFHARVADRWR 284
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 17562934  298 SikcsphsffDNLVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:PRK06183 285 S---------GRVLLAGDAAHLMPPFAGQGMNSGIRD 312
PRK06126 PRK06126
hypothetical protein; Provisional
3-334 1.43e-08

hypothetical protein; Provisional


Pssm-ID: 235704 [Multi-domain]  Cd Length: 545  Bit Score: 56.93  E-value: 1.43e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    3 SVAIAGAGLVGALNACFFAQKGWDVSVYEfRKDIRT----MKHVQGRSIN----LALSQrgksALEAVGL-KEYivNQGV 73
Cdd:PRK06126   9 PVLIVGGGPVGLALALDLGRRGVDSILVE-RKDGTAfnpkANTTSARSMEhfrrLGIAD----EVRSAGLpVDY--PTDI 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   74 PLYARL----IHNKDGKTySRQPYGKPGEHIVS---------INRRHLNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQL 140
Cdd:PRK06126  82 AYFTRLtgyeLARFRLPS-AREAITPVGGPDGSwpspelphrIPQKYLEPILLEHAAAQPGVTLRYGHRLTDFEQDADGV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  141 VVQCTsqpskiPTFGNKSppqehaeFHVEADLILACDGAYSAVRRSL-----------------MTIPRFdfsQEYIEHG 203
Cdd:PRK06126 161 TATVE------DLDGGES-------LTIRADYLVGCDGARSAVRRSLgisyegtsglqrdlsiyIRAPGL---AALVGHD 224
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  204 ----YVELNimannnefafeenvfhlwPRGHFTLIALANRDkTFTVTIFAPfSEFEKHmSTSEDVLSFFE----ENFPda 275
Cdd:PRK06126 225 pawmYWLFN------------------PDRRGVLVAIDGRD-EWLFHQLRG-GEDEFT-IDDVDARAFVRrgvgEDID-- 281
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 17562934  276 FLLLGKEH------IADTFNRvkpqplvsikcsphsffDNLVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:PRK06126 282 YEVLSVVPwtgrrlVADSYRR-----------------GRVFLAGDAAHLFTPTGGYGMNTGIGD 329
PRK08849 PRK08849
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
4-363 8.26e-08

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 181564 [Multi-domain]  Cd Length: 384  Bit Score: 54.01  E-value: 8.26e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEFRKDiRTMKHVQGRSINL-ALSQRGKSALEAVGLKEYIVNQGVPLYARLihn 82
Cdd:PRK08849   6 IAVVGGGMVGAATALGFAKQGRSVAVIEGGEP-KAFEPSQPMDIRVsAISQTSVDLLESLGAWSSIVAMRVCPYKRL--- 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   83 kdgKTYsrqpygkpgEHIVSINRRHLNEVMITQaekspnVKFFFEHKVKNV-------DYDkkQLVVQCTSQPSKIPTF- 154
Cdd:PRK08849  82 ---ETW---------EHPECRTRFHSDELNLDQ------LGYIVENRLIQLglwqqfaQYP--NLTLMCPEKLADLEFSa 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  155 -GNKSPPQEHAEFhvEADLILACDGAYSAVRRSL-MTIPRFDFSQeyiehgyvelNIMANNNEFAFEENVFhLW----PR 228
Cdd:PRK08849 142 eGNRVTLESGAEI--EAKWVIGADGANSQVRQLAgIGITAWDYRQ----------HCMLINVETEQPQQDI-TWqqftPS 208
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  229 GHFTLIALANRDKTFtVTIFAPFSEFEKHMSTSEDVLSFFEENFPDAfllLGK----EHIADTFNRVKPQPLVSIKCsph 304
Cdd:PRK08849 209 GPRSFLPLCGNQGSL-VWYDSPKRIKQLSAMNPEQLRSEILRHFPAE---LGEikvlQHGSFPLTRRHAQQYVKNNC--- 281
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 17562934  305 sffdnlVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGNDIAKAVKVYSDGRVND 363
Cdd:PRK08849 282 ------VLLGDAAHTINPLAGQGVNLGFKDVDVLLAETEKQGVLNDASFARYERRRRPD 334
PRK06475 PRK06475
FAD-binding protein;
3-360 2.03e-07

FAD-binding protein;


Pssm-ID: 180582 [Multi-domain]  Cd Length: 400  Bit Score: 52.90  E-value: 2.03e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    3 SVAIAGAGLVGALNACFFAQKGWDVSVYEFRKDIRTMkhvqGRSINLAlsQRGKSALEAVGLKEYIVNQGV-PLYARLIH 81
Cdd:PRK06475   4 SPLIAGAGVAGLSAALELAARGWAVTIIEKAQELSEV----GAGLQLA--PNAMRHLERLGVADRLSGTGVtPKALYLMD 77
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   82 NKDGKTYSRQPYGKPGEH-----IVSINRRHLNEVMITQAEKSPNVKfffehkvknvdYDKKQLVVQCTSQPSKIptfgN 156
Cdd:PRK06475  78 GRKARPLLAMQLGDLARKrwhhpYIVCHRADLQSALLDACRNNPGIE-----------IKLGAEMTSQRQTGNSI----T 142
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  157 KSPPQEHAEFHVEADLILACDGAYSAVRrSLMTIPRFDFSqeyiehGYV--ELNIMANNNEFAF-----EENVFHLW--P 227
Cdd:PRK06475 143 ATIIRTNSVETVSAAYLIACDGVWSMLR-AKAGFSKARFS------GHIawRTTLAADALPASFlsampEHKAVSAWlgN 215
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  228 RGHFTLIALANrDKTFT---VTIFAPFSEFEKHMSTSEDVLSFFEENFPDAFlllgkeHIADTFNRVKPQPLVSIKCSPH 304
Cdd:PRK06475 216 KAHFIAYPVKG-GKFFNfvaITGGENPGEVWSKTGDKAHLKSIYADWNKPVL------QILAAIDEWTYWPLFEMADAQF 288
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 17562934  305 SFFDNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEygNDIAKAVKVYSDGR 360
Cdd:PRK06475 289 VGPDRTIFLGDASHAVTPFAAQGAAMAIEDAAALAEALDS--DDQSAGLKRFDSVR 342
PRK07045 PRK07045
putative monooxygenase; Reviewed
4-364 2.45e-07

putative monooxygenase; Reviewed


Pssm-ID: 136171 [Multi-domain]  Cd Length: 388  Bit Score: 52.60  E-value: 2.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEfrkdiRTMKHvqgRSINLA--LSQRGKSALEAVGLKEYIVNQG--VPLYARL 79
Cdd:PRK07045   8 VLINGSGIAGVALAHLLGARGHSVTVVE-----RAARN---RAQNGAdlLKPSGIGVVRAMGLLDDVFAAGglRRDAMRL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   80 IHNKDGKTYSRQPYGKPGEHIVSINRRHLNEVMITQAEKSPNVKFFFEHKVKNVDYDKKQLVVQCTSQPSKIptfgnksp 159
Cdd:PRK07045  80 YHDKELIASLDYRSASALGYFILIPCEQLRRLLLAKLDGLPNVRLRFETSIERIERDADGTVTSVTLSDGER-------- 151
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  160 pqehaefhVEADLILACDGAYSAVRRSLMTIP--RFDFSQEYIEHGYVELNIMANNNEFAFEEN--VFHLWPRGHftlia 235
Cdd:PRK07045 152 --------VAPTVLVGADGARSMIRDDVLRMPaeRVPYATPMAFGTIALTDSVRECNRLYVDSNqgLAYFYPIGD----- 218
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  236 lanrDKTFTVTIFaPFSEFEKHM--STSEDVLS----FFEENFPDAFLLLGKEhiadtfNRVKPQPLVSIKCSPHsFFDN 309
Cdd:PRK07045 219 ----QATRLVVSF-PADEMQGYLadTTRTKLLArlneFVGDESADAMAAIGAG------TAFPLIPLGRMNLDRY-HKRN 286
                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGND---IAKAVKVYSDGR--VNDA 364
Cdd:PRK07045 287 VVLLGDAAHSIHPITGQGMNLAIEDAGELGACLDLHLSGqiaLADALERFERIRrpVNEA 346
PRK05868 PRK05868
FAD-binding protein;
1-400 4.70e-07

FAD-binding protein;


Pssm-ID: 180297 [Multi-domain]  Cd Length: 372  Bit Score: 51.91  E-value: 4.70e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    1 MPSVAIAGAGLVGALNACFFAQKGWDVSVYEfrkdirtmKHVQGRSINLALSQRGKS--ALEAVGLKEYIVNQGVPLYAR 78
Cdd:PRK05868   1 MKTVVVSGASVAGTAAAYWLGRHGYSVTMVE--------RHPGLRPGGQAIDVRGPAldVLERMGLLAAAQEHKTRIRGA 72
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   79 LIHNKDGKTYSRQ----PYGKPGEHI-VSINRRHLNEVMITQAEksPNVKFFFEHKVKNVDYDKKQLVVqctsqpskipT 153
Cdd:PRK05868  73 SFVDRDGNELFRDtestPTGGPVNSPdIELLRDDLVELLYGATQ--PSVEYLFDDSISTLQDDGDSVRV----------T 140
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  154 FGNKSPPqehaefhvEADLILACDGAYSAVRRSLmtiprFDFSQEYIEHGYVELNIMANNNefAFEENVFHLWPRGHFTL 233
Cdd:PRK05868 141 FERAAAR--------EFDLVIGADGLHSNVRRLV-----FGPEEQFVKRLGTHAAIFTVPN--FLELDYWQTWHYGDSTM 205
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  234 IAL-ANRDKTFTVTIFApFSEFEKHMSTSEDVLSFFEenfpdafllLGKEHIADTFnrVKPQPLVSIKCSPHSFFDNL-- 310
Cdd:PRK05868 206 AGVySARNNTEARAALA-FMDTELRIDYRDTEAQFAE---------LQRRMAEDGW--VRAQLLHYMRSAPDFYFDEMsq 273
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  311 -----------VLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGNDiakavkvYSDGRVNDAHSINDLAMYNYEELK 379
Cdd:PRK05868 274 ilmdrwsrgrvALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGDD-------YQLGFANYHAEFHGFVERNQWLVS 346
                        410       420
                 ....*....|....*....|.
gi 17562934  380 DLVNKSSYKLRKKFDTIMNSI 400
Cdd:PRK05868 347 DNIPGGAPIPQEEFERIVHSI 367
PTZ00367 PTZ00367
squalene epoxidase; Provisional
4-371 1.01e-06

squalene epoxidase; Provisional


Pssm-ID: 240384 [Multi-domain]  Cd Length: 567  Bit Score: 51.00  E-value: 1.01e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    4 VAIAGAGLVGALNACFFAQKGWDVSVYEfrkdiRTMKHVQGRSINLALSQRGKSALEAVGLKEYIVNQGVPLYARLIHNK 83
Cdd:PTZ00367  36 VIIVGGSIAGPVLAKALSKQGRKVLMLE-----RDLFSKPDRIVGELLQPGGVNALKELGMEECAEGIGMPCFGYVVFDH 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   84 DGKTySRQPYGKP--------GEHIVSINRR--HLNEVMITQAEKSPNV----KFFFEHKVKNVDYDKKQLVVQCTSQPS 149
Cdd:PTZ00367 111 KGKQ-VKLPYGAGasgvsfhfGDFVQNLRSHvfHNCQDNVTMLEGTVNSlleeGPGFSERAYGVEYTEAEKYDVPENPFR 189
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  150 KIPTFGNKSPPQEHAEfhVEADLILACDGAYSAVRRSLMTiprFDFSQEYIEHgYVELNIMANNNEFAFEENVFhLWPRG 229
Cdd:PTZ00367 190 EDPPSANPSATTVRKV--ATAPLVVMCDGGMSKFKSRYQH---YTPASENHSH-FVGLVLKNVRLPKEQHGTVF-LGKTG 262
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  230 HFTLIALANRDKTFTVTIFAPFSEFEKHMST--SEDVLSFFEENFPDAFLLLGKE--HIADTFNRVKPQPLVSIKcsphs 305
Cdd:PTZ00367 263 PILSYRLDDNELRVLVDYNKPTLPSLEEQSEwlIEDVAPHLPENMRESFIRASKDtkRIRSMPNARYPPAFPSIK----- 337
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  306 ffdNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETL----EEYGND----------IAKAVKVYSDGRVNDAHSINDLA 371
Cdd:PTZ00367 338 ---GYVGIGDHANQRHPLTGGGMTCCFSDCIRLAKSLtgikSLRSIDqnemaeiedaIQAAILSYARNRKTHASTINILS 414
PRK08255 PRK08255
bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;
164-360 1.99e-06

bifunctional salicylyl-CoA 5-hydroxylase/oxidoreductase;


Pssm-ID: 236203 [Multi-domain]  Cd Length: 765  Bit Score: 50.32  E-value: 1.99e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  164 AEFHVEADLILACDGAYSAVRRS------------------LMTIPRFD-FSqeyiehgyvelnimannneFAFEENvfh 224
Cdd:PRK08255 124 QALAADADLVIASDGLNSRIRTRyadtfqpdidtrrcrfvwLGTHKVFDaFT-------------------FAFEET--- 181
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  225 lwPRGHFTLIALANRDKTFTVTIFAPFSEFEKH----MStSEDVLSFFEENFPDAF----LLLGKEHIADT----FNRVK 292
Cdd:PRK08255 182 --EHGWFQAHAYRFDDDTSTFIVETPEEVWRAAgldeMS-QEESIAFCEKLFADYLdghpLMSNASHLRGSawinFPRVV 258
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 17562934  293 PQPLVSIKCSPHsffdnLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEYGNDIAKAVKVYSDGR 360
Cdd:PRK08255 259 CERWVHWNRRVP-----VVLMGDAAHTAHFSIGSGTKLALEDAIELARCLHEHPGDLPAALAAYEEER 321
COQ6 TIGR01989
ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase ...
4-349 1.03e-04

ubiquinone biosynthesis monooxygenase COQ6; This model represents the monooxygenase responsible for the 4-hydroxylateion of the phenol ring in the aerobic biosynthesis of ubiquinone


Pssm-ID: 273914 [Multi-domain]  Cd Length: 437  Bit Score: 44.36  E-value: 1.03e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934     4 VAIAGAGLVGALNACffaqkgwdvsvyefrkDIRTMKHVQGRSINLALSQRGKSALEAVGLK--EYIVNQGVPLYARLIH 81
Cdd:TIGR01989   3 VVIVGGGPVGLALAA----------------ALGNNPLTKDLKVLLLDAVDNPKLKSRNYEKpdGPYSNRVSSITPASIS 66
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    82 ----NKDGKTYSRQPYgKPGEHIVSINRRHLNEVMITQAEKSPNVKFFFEHKV--------------KNVDYDKKQLVVQ 143
Cdd:TIGR01989  67 ffkkIGAWDHIQSDRI-QPFGRMQVWDGCSLALIRFDRDNGKEDMACIIENDNiqnslynrlqeyngDNVKILNPARLIS 145
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   144 CTsQPSKIPtfGNKSPpqeHAEFHVE------ADLILACDGAYSAVRRSlMTIPRFDFSqeYIEHGYV-ELNI-MANNNE 215
Cdd:TIGR01989 146 VT-IPSKYP--NDNSN---WVHITLSdgqvlyTKLLIGADGSNSNVRKA-ANIDTTGWN--YNQHAVVaTLKLeEATEND 216
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   216 FAFEEnvfhLWPRGHFTLIALANRDKTFTVTIfAPfSEFEKHMSTSED-----VLSFFEENFPDA--------------- 275
Cdd:TIGR01989 217 VAWQR----FLPTGPIALLPLPDNNSTLVWST-SP-EEALRLLSLPPEdfvdaLNAAFDLGYSDHpysylldyameklne 290
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   276 ---FLLLGKEHiadtfNRVKPQPLVSIKCSPHSFF------------DNLVLMGDAAHAMVPFYGQGMNCGFEDCLVFSE 340
Cdd:TIGR01989 291 digFRTEGSKS-----CFQVPPRVIGVVDKSRAAFplglghadeyvtKRVALVGDAAHRVHPLAGQGVNLGFGDVASLVK 365
                         410
                  ....*....|..
gi 17562934   341 TLEE---YGNDI 349
Cdd:TIGR01989 366 ALAEavsVGADI 377
PRK05714 PRK05714
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional
310-357 1.26e-04

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Provisional


Pssm-ID: 168201 [Multi-domain]  Cd Length: 405  Bit Score: 44.05  E-value: 1.26e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLE---EYGNDIAKaVKVYS 357
Cdd:PRK05714 287 LALIGDAAHTIHPLAGQGVNLGFLDAAVLAEVLLhaaERGERLAD-VRVLS 336
PRK06185 PRK06185
FAD-dependent oxidoreductase;
3-329 1.69e-04

FAD-dependent oxidoreductase;


Pssm-ID: 235729 [Multi-domain]  Cd Length: 407  Bit Score: 43.69  E-value: 1.69e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934    3 SVAIAGAGLVGALNACFFAQKGWDVSVYE----FRKDIRtmkhvqGRSIN---LALsqrgksaLEAVGLKEYivnqgvpl 75
Cdd:PRK06185   8 DCCIVGGGPAGMMLGLLLARAGVDVTVLEkhadFLRDFR------GDTVHpstLEL-------MDELGLLER-------- 66
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934   76 YARLIHNKdgktySRQPYGK-PGEHIVSINRRHLN---------------EVMITQAEKSPNVKFFFEHKVKNVDYDKKQ 139
Cdd:PRK06185  67 FLELPHQK-----VRTLRFEiGGRTVTLADFSRLPtpypyiammpqwdflDFLAEEASAYPNFTLRMGAEVTGLIEEGGR 141
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  140 LV-VQCTsqpskiptfgnksppQEHAEFHVEADLILACDGAYSAVRRSL-MTIPRFDFSQEYIehgYVELNIMANnnefA 217
Cdd:PRK06185 142 VTgVRAR---------------TPDGPGEIRADLVVGADGRHSRVRALAgLEVREFGAPMDVL---WFRLPREPD----D 199
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  218 FEENVFHLWPRGHFTLIalaNRDKTFTVTIFAPFSEFEKHMSTSEDVL-SFFEENFPDAflllgKEHIAD--TFNRVKpq 294
Cdd:PRK06185 200 PESLMGRFGPGQGLIMI---DRGDYWQCGYVIPKGGYAALRAAGLEAFrERVAELAPEL-----ADRVAElkSWDDVK-- 269
                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 17562934  295 pLVSIKCS--PHSFFDNLVLMGDAAHAMVPFYGQGMN 329
Cdd:PRK06185 270 -LLDVRVDrlRRWHRPGLLCIGDAAHAMSPVGGVGIN 305
PRK07608 PRK07608
UbiH/UbiF family hydroxylase;
310-334 3.15e-04

UbiH/UbiF family hydroxylase;


Pssm-ID: 181057 [Multi-domain]  Cd Length: 388  Bit Score: 43.02  E-value: 3.15e-04
                         10        20
                 ....*....|....*....|....*
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:PRK07608 282 VALVGDAAHLIHPLAGQGMNLGLRD 306
PRK08013 PRK08013
oxidoreductase; Provisional
310-334 7.12e-04

oxidoreductase; Provisional


Pssm-ID: 236139 [Multi-domain]  Cd Length: 400  Bit Score: 41.95  E-value: 7.12e-04
                         10        20
                 ....*....|....*....|....*
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:PRK08013 284 LALVGDAAHTIHPLAGQGVNLGFMD 308
PRK06847 PRK06847
hypothetical protein; Provisional
310-360 9.43e-04

hypothetical protein; Provisional


Pssm-ID: 235874 [Multi-domain]  Cd Length: 375  Bit Score: 41.40  E-value: 9.43e-04
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|.
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEEyGNDIAKAVKVYSDGR 360
Cdd:PRK06847 284 VVLIGDAAHATTPHLAQGAGMAIEDAIVLAEELAR-HDSLEAALQAYYARR 333
PRK07333 PRK07333
ubiquinone biosynthesis hydroxylase;
310-352 1.79e-03

ubiquinone biosynthesis hydroxylase;


Pssm-ID: 180935 [Multi-domain]  Cd Length: 403  Bit Score: 40.35  E-value: 1.79e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*.
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSETLEE---YGNDIAKA 352
Cdd:PRK07333 282 FALVGDAAHGIHPIAGQGLNLGLKDVAALAEVVVEaarLGLDIGSL 327
PRK08850 PRK08850
2-octaprenyl-6-methoxyphenol hydroxylase; Validated
170-349 2.86e-03

2-octaprenyl-6-methoxyphenol hydroxylase; Validated


Pssm-ID: 236341 [Multi-domain]  Cd Length: 405  Bit Score: 39.75  E-value: 2.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  170 ADLILACDGAYSAVRRSlMTIPrfdfsqeyIEHgyvelnimannnefafeenvfhlWPRGHFTLIAlanrdktfTVTIFA 249
Cdd:PRK08850 157 AKLVVGADGANSWLRRQ-MDIP--------LTH-----------------------WDYGHSALVA--------NVRTVD 196
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17562934  250 PfsefekHMSTSEDVlsfFEENFPDAFLLLGKEHIADTFNRVKP---QPLVSikCSPHSF-------FDN---------- 309
Cdd:PRK08850 197 P------HNSVARQI---FTPQGPLAFLPMSEPNMSSIVWSTEPlraEALLA--MSDEQFnkaltaeFDNrlglcevvge 265
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 17562934  310 ------------------LVLMGDAAHAMVPFYGQGMNCGFEDCLVFSE---TLEEYGNDI 349
Cdd:PRK08850 266 rqafplkmryardfvrerVALVGDAAHTIHPLAGQGVNLGLLDAASLAQeilALWQQGRDI 326
ubiF PRK08020
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed
310-334 4.37e-03

2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Reviewed


Pssm-ID: 181199 [Multi-domain]  Cd Length: 391  Bit Score: 39.20  E-value: 4.37e-03
                         10        20
                 ....*....|....*....|....*
gi 17562934  310 LVLMGDAAHAMVPFYGQGMNCGFED 334
Cdd:PRK08020 283 LALVGDAAHTINPLAGQGVNLGYRD 307
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
1-31 7.38e-03

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 38.49  E-value: 7.38e-03
                         10        20        30
                 ....*....|....*....|....*....|.
gi 17562934    1 MPSVAIAGAGLVGALNACFFAQKGWDVSVYE 31
Cdd:PRK06129   2 MGSVAIIGAGLIGRAWAIVFARAGHEVRLWD 32
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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