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Conserved domains on  [gi|17563302|ref|NP_506332|]
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Serpentine Receptor, class D (Delta) [Caenorhabditis elegans]

Protein Classification

class D serpentine receptor( domain architecture ID 10563389)

class D serpentine receptor (Srd) belongs to a family of seven-transmembrane (7TM) G protein-coupled receptors involved in chemoreception, a central sense of soil nematodes like Caenorhabditis elegans

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-299 4.79e-91

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


:

Pssm-ID: 402094  Cd Length: 292  Bit Score: 273.66  E-value: 4.79e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302     5 FEIWHCIWALLGCSFNLMLIYMAIYKSPKTIRSYATLIINFAVTDFFECALDLFIQIRLMPapGDVTVIYILNGSCKYIS 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP--NGVSMALISYGPCKYFG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    85 QFACKIGLSLFLPCITHSVWSLLLSFGYRYYILHYSALTRLKLVKIVLLILIPSLFQGLTFWTSFAPLEIILPLAKKWFP 164
Cdd:pfam10317  79 PWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   165 QYNFEAETgvLTGIVDITHWAATYAVFNICLPIFPIYIAIFILRQKIITFLGAKTQSMSPDTKAAHSQLLKALTIQAFIP 244
Cdd:pfam10317 159 NYNLTDYT--VTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLP 236
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 17563302   245 IFMGI-GVIFYLIAQSGLIVSPIVENAIFSIAILMPALSPLTYFYFVRPYRQFLKR 299
Cdd:pfam10317 237 LFSYIpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-299 4.79e-91

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 273.66  E-value: 4.79e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302     5 FEIWHCIWALLGCSFNLMLIYMAIYKSPKTIRSYATLIINFAVTDFFECALDLFIQIRLMPapGDVTVIYILNGSCKYIS 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP--NGVSMALISYGPCKYFG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    85 QFACKIGLSLFLPCITHSVWSLLLSFGYRYYILHYSALTRLKLVKIVLLILIPSLFQGLTFWTSFAPLEIILPLAKKWFP 164
Cdd:pfam10317  79 PWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   165 QYNFEAETgvLTGIVDITHWAATYAVFNICLPIFPIYIAIFILRQKIITFLGAKTQSMSPDTKAAHSQLLKALTIQAFIP 244
Cdd:pfam10317 159 NYNLTDYT--VTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLP 236
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 17563302   245 IFMGI-GVIFYLIAQSGLIVSPIVENAIFSIAILMPALSPLTYFYFVRPYRQFLKR 299
Cdd:pfam10317 237 LFSYIpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
 
Name Accession Description Interval E-value
7TM_GPCR_Srd pfam10317
Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis ...
5-299 4.79e-91

Serpentine type 7TM GPCR chemoreceptor Srd; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srd is part of the larger Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402094  Cd Length: 292  Bit Score: 273.66  E-value: 4.79e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302     5 FEIWHCIWALLGCSFNLMLIYMAIYKSPKTIRSYATLIINFAVTDFFECALDLFIQIRLMPapGDVTVIYILNGSCKYIS 84
Cdd:pfam10317   1 FSIYYPIFFILGLILNLLLLYLIIFKSPKSLKTYRILLLNTAITQIISCILAFFTQQRIIP--NGVSMALISYGPCKYFG 78
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    85 QFACKIGLSLFLPCITHSVWSLLLSFGYRYYILHYSALTRLKLVKIVLLILIPSLFQGLTFWTSFAPLEIILPLAKKWFP 164
Cdd:pfam10317  79 PWFCYSGYSLLQHFLLHSGWSLLLTFYYRYYILKHVDPKRKKLILLIIIHYIPSLSQLIVIFLSPTDFLPVEALTKELHP 158
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   165 QYNFEAETgvLTGIVDITHWAATYAVFNICLPIFPIYIAIFILRQKIITFLGAKTQSMSPDTKAAHSQLLKALTIQAFIP 244
Cdd:pfam10317 159 NYNLTDYT--VTGFSDLQSFPALINTLIMTIPVFPIPIIILILRRKILKLLNSNSVNMSPTTKAQHRQLIKGLTIQALLP 236
                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 17563302   245 IFMGI-GVIFYLIAQSGLIVSPIVENAIFSIAILMPALSPLTYFYFVRPYRQFLKR 299
Cdd:pfam10317 237 LFSYIpGVTLYLLSQLTGTEFLILEYFIFVLPALPPLLDPLITIYFVTPYRRAILR 292
7TM_GPCR_Str pfam10326
Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis ...
13-298 1.16e-09

Serpentine type 7TM GPCR chemoreceptor Str; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Str is a member of the Str superfamily of chemoreceptors. Almost a quarter (22.5%) of str and srj family genes and pseudogenes in C. elegans appear to have been newly formed by gene duplications since the species split. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402099  Cd Length: 307  Bit Score: 58.62  E-value: 1.16e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    13 ALLGCSFNLMLIYMAIYKSPKTIRSYATLIINFAVTDFFECALDLFIQirlmpaPG----DVTVIYILNGSCKYISQFAC 88
Cdd:pfam10326   9 FFLSILLNSILIYLILFKSPKIFGTYKYLMIYFSIFGIFFSILEFIVK------PFihsyNSSFIVFVDLKDLGLSKSVG 82
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    89 KIGLSLFLPCITHSVWSLLLSFGYRYYIL-HYSALTRLKLVKIVLLILIPSLF---QGLTFWTSFAP-----------LE 153
Cdd:pfam10326  83 QILLALYCGFYGVSISLLAVQFIYRYLALcRPGKLKYFDGKKLILWFLYPLIFgaiWGLLVYFFLGPdeetdeylreeLL 162
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   154 IILPLAKKWFPQYNFEAETGVLTGIVDItHWAATYAVFNICLPIFPIYIAIFILRQKIITFLGAKTQSMSPDTKAAHSQL 233
Cdd:pfam10326 163 ENYNLDIDEVAYVGPVYYPTDENGSKVI-RWRSLIGLLIMTFIIGISFSIIIYCGIKMYFKMKKLKSLGSEKTRKLQKQL 241
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 17563302   234 LKALTIQAFIP-IFMGIGVIFYLIAQS-GLIVSPIVENAIFSIAIlMPALSPLTYFYFVRPYRQFLK 298
Cdd:pfam10326 242 FKALVIQTLIPtILMYIPVGILFLLPLfNIEIGFLSGIITATIAL-YPAIDPLPAMFIIKEYRNAIK 307
7TM_GPCR_Srj pfam10319
Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis ...
17-246 1.74e-08

Serpentine type 7TM GPCR chemoreceptor Srj; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srj is part of the Str superfamily of chemoreceptors. The srj family is designated as the out-group based on its location in preliminary phylogenetic analyses of the entire superfamily. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 370974  Cd Length: 310  Bit Score: 54.94  E-value: 1.74e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    17 CSF--NLMLIYMAIYKSPKTIRSYATLIINFAVTDFFECALDLFIQIRlMPAPGDVTVIYILNGSCKYISQFAcKIGLSL 94
Cdd:pfam10319  17 LSFivNPIFIYLIFTEKSSQFGNYRYLLLFFAIFNLIYSVVELLVPLD-IHSYRYCFVVFVSDGPFFEYSELG-QHALSA 94
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302    95 FLPCITHSVWSLLLSFGYRYYILHYSALTRLKLVKIVLLILIPSLFQGLTFWT------SFAPLEIILPLAKKWFPQYNf 168
Cdd:pfam10319  95 RCSFISASYAVLLIHFIYRYLVLFNPQLTRHYFRPWGILISILFFLFHGSVWTaicyflLRANDEIRDYIREDFRETYG- 173
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   169 eAETGVLTGIVDITHWAATYAVFN-----ICLPIFPIY--IAIFILRQKIITFLGAKTQSMSPDTKAAHSQLLKALTIQA 241
Cdd:pfam10319 174 -VDSMDINMLGALYWEASDETVFRswlgiLLLTVISVYsiILYIVLGYKIMRKLNKMSVTMSKKTKRLQKQLLKALIVQT 252

                  ....*
gi 17563302   242 FIPIF 246
Cdd:pfam10319 253 IIPIC 257
7TM_GPCR_Srh pfam10318
Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis ...
191-302 1.50e-05

Serpentine type 7TM GPCR chemoreceptor Srh; Chemoreception is mediated in Caenorhabditis elegans by members of the seven-transmembrane G-protein-coupled receptor class (7TM GPCRs) of proteins which are of the serpentine type. Srh is part of the Str superfamily of chemoreceptors. Chemoperception is one of the central senses of soil nematodes like C. elegans which are otherwise 'blind' and 'deaf'.


Pssm-ID: 402095  Cd Length: 302  Bit Score: 46.00  E-value: 1.50e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 17563302   191 FNICLPIFPIYIAIFILRQKIITF---LGAKTQSMSPDTKAAHSQLLKALTIQAFIP-IFMGIGVIFYLIAQSGLIVSPI 266
Cdd:pfam10318 186 FLICIVLLILILIIQILFFVFLTIyylFKSVKSSLSKKTRKLQKKFFIALIIQVSIPlIVILIPLIYILFSIIFGYYNQA 265
                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 17563302   267 VENAIFSIAILMPALSPLTYFYFVRPYRQFLKRIFK 302
Cdd:pfam10318 266 LNNLLFIIISLHGLLSTIAMLLVHKPYRKFVLSLFK 301
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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