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Conserved domains on  [gi|17563064|ref|NP_506461|]
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Protein SNA3 [Caenorhabditis elegans]

Protein Classification

YqaE/Pmp3 family membrane protein( domain architecture ID 10483657)

YqaE/Pmp3 family membrane protein similar to fungal plasma membrane proteolipid 3, which may play a role in regulating plasma membrane potential

Gene Ontology:  GO:0016020

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 26-75 1.56e-12

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


:

Pssm-ID: 460290  Cd Length: 49  Bit Score: 56.25  E-value: 1.56e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 17563064   26 RLVMALMWLILPPMAVYFKsRGCTKHVCLNVLLYFFLILPSYIHATWYCF 75
Cdd:pfam01679  1 DILLIILAIFLPPLAVFLK-RGCGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Name Accession Description Interval E-value
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 26-75 1.56e-12

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 56.25  E-value: 1.56e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 17563064   26 RLVMALMWLILPPMAVYFKsRGCTKHVCLNVLLYFFLILPSYIHATWYCF 75
Cdd:pfam01679  1 DILLIILAIFLPPLAVFLK-RGCGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Name Accession Description Interval E-value
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 26-75 1.56e-12

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 56.25  E-value: 1.56e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|
gi 17563064   26 RLVMALMWLILPPMAVYFKsRGCTKHVCLNVLLYFFLILPSYIHATWYCF 75
Cdd:pfam01679  1 DILLIILAIFLPPLAVFLK-RGCGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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