NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|115534998|ref|NP_508935|]
View 

UPF0057 membrane protein T23F2.4 [Caenorhabditis elegans]

Protein Classification

YqaE/Pmp3 family membrane protein( domain architecture ID 10001368)

YqaE/Pmp3 family membrane protein similar to Escherichia coli UPF0057 membrane protein YqaE, fungal plasma membrane proteolipid 3, and Arabidopsis thaliana hydrophobic proteins RCI2A and RCI2B

Gene Ontology:  GO:0016020

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
YqaE COG0401
Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 ...
 6-57 1.84e-12

Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 family [Energy production and conversion];


:

Pssm-ID: 440170  Cd Length: 53  Bit Score: 54.81  E-value: 1.84e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 115534998  6 MDIPKFLFALLLPPVGVFLEKGCTHHLAICILLTILGYIPGIIYACYIILAY 57
Cdd:COG0401   1 MDLLRIILAILLPPLGVFLTVGLGKTFWINILLTLLGWIPGIIHALWVIAKR 52
 
Name Accession Description Interval E-value
YqaE COG0401
Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 ...
 6-57 1.84e-12

Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 family [Energy production and conversion];


Pssm-ID: 440170  Cd Length: 53  Bit Score: 54.81  E-value: 1.84e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 115534998  6 MDIPKFLFALLLPPVGVFLEKGCTHHLAICILLTILGYIPGIIYACYIILAY 57
Cdd:COG0401   1 MDLLRIILAILLPPLGVFLTVGLGKTFWINILLTLLGWIPGIIHALWVIAKR 52
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 7-55 2.44e-10

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 49.31  E-value: 2.44e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 115534998   7 DIPKFLFALLLPPVGVFLEKGCTHHLAICILLTILGYIPGIIYACYIIL 55
Cdd:pfam01679  1 DILLIILAIFLPPLAVFLKRGCGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Name Accession Description Interval E-value
YqaE COG0401
Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 ...
 6-57 1.84e-12

Membrane potential modulator PMP3/YqaE, plasma membrane proteolipid 3 (PMP3)/Esi3/RCI2/UPF0057 family [Energy production and conversion];


Pssm-ID: 440170  Cd Length: 53  Bit Score: 54.81  E-value: 1.84e-12
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|..
gi 115534998  6 MDIPKFLFALLLPPVGVFLEKGCTHHLAICILLTILGYIPGIIYACYIILAY 57
Cdd:COG0401   1 MDLLRIILAILLPPLGVFLTVGLGKTFWINILLTLLGWIPGIIHALWVIAKR 52
Pmp3 pfam01679
Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in ...
 7-55 2.44e-10

Proteolipid membrane potential modulator; Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organizms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.


Pssm-ID: 460290  Cd Length: 49  Bit Score: 49.31  E-value: 2.44e-10
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*....
gi 115534998   7 DIPKFLFALLLPPVGVFLEKGCTHHLAICILLTILGYIPGIIYACYIIL 55
Cdd:pfam01679  1 DILLIILAIFLPPLAVFLKRGCGKDFLINILLTLLGWIPGIIHALYIIY 49
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH