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Conserved domains on  [gi|453232805|ref|NP_509053|]
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Protein lev-9 [Caenorhabditis elegans]

Protein Classification

beta-2-glycoprotein 1( domain architecture ID 12867676)

beta-2-glycoprotein 1 is a heavily glycosylated plasma membrane-adhesion protein, which plays a role in blood coagulation and removal of apoptotic bodies

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 127-363 3.61e-25

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 3.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927  27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927 100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927 180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256


                 ....*.
gi 453232805 358 PIPRCL 363
Cdd:PHA02927 257 ELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 64-119 5.94e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


:

Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.94e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033    1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02927 super family cl33700
secreted complement-binding protein; Provisional
 377-557 3.34e-09

secreted complement-binding protein; Provisional


The actual alignment was detected with superfamily member PHA02927:

Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 3.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927  90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927 169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229

                        170       180       190
                 ....*....|....*....|....*....|....
gi 453232805 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927 230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 127-363 3.61e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 3.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927  27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927 100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927 180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256


                 ....*.
gi 453232805 358 PIPRCL 363
Cdd:PHA02927 257 ELPKCV 262
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 193-247 1.13e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.87  E-value: 1.13e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805 193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANCK 247
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYgsTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 64-119 5.94e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.94e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033    1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 64-118 1.33e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.85  E-value: 1.33e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805    64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 193-246 7.24e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 7.24e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYgdTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 377-557 3.34e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 3.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927  90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927 169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229

                        170       180       190
                 ....*....|....*....|....*....|....
gi 453232805 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927 230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
Sushi pfam00084
Sushi repeat (SCR repeat);
309-362 3.48e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.48e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805  309 CSVLPTLPNGYIEGS--ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
64-118 1.82e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.82e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:pfam00084   1 CPPPPDIPNGKVSaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 425-481 1.89e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.75  E-value: 1.89e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPnRNNQIIKCL-YGEWTkdGPPMKC 481
Cdd:cd00033    1 CPP-PPVPENGTVTGSKGsySYGSTVTYSCNEGYTL-VGSSTITCTeNGGWS--PPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 425-481 2.52e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 2.52e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805   425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPNRNNqIIKCL-YGEWTkdGPPMKC 481
Cdd:smart00032   1 CPP-PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS-TITCLeNGTWS--PPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
520-556 8.62e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.78  E-value: 8.62e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 453232805  520 EEGRAISFQCGKGNYLIGPPKATCV-NGEWMPKVsPKC 556
Cdd:pfam00084  20 NYGASVSYECDPGYRLVGSPTITCQeDGTWSPPF-PEC 56
 
Name Accession Description Interval E-value
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 127-363 3.61e-25

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 105.12  E-value: 3.61e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 127 PPEIPFAVHDGSSFSGEYDLDAEVAYNCIPGYHKfNAKGLSISKCLLNRKNVAQwfgpdlRCKARACPDPGDIENGLREG 206
Cdd:PHA02927  27 PINMKFKNSVETDANANYNIGDTIEYLCLPGYRK-QKMGPIYAKCTGTGWTLFN------QCIKRRCPSPRDIDNGQLDI 99

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCS--SNGE--WTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG 280
Cdd:PHA02927 100 GGVDFGSSITYSCNSGYQLIGESKSYCElgSTGSmvWNPEAPICESVKCQSPPSISNGRHNGYEDFYTdgSVVTYSCNSG 179

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 281 YRLVGQVQRIClAEGIWgGNEPRCEEIRCSvLPTLPNGYIEGS---ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSA 357
Cdd:PHA02927 180 YSLIGNSGVLC-SGGEW-SDPPTCQIVKCP-HPTISNGYLSSGfkrSYSYNDNVDFKCKYGYKLSGSSSSTCSPGNTWQP 256


                 ....*.
gi 453232805 358 PIPRCL 363
Cdd:PHA02927 257 ELPKCV 262
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 66-246 2.04e-16

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 79.70  E-value: 2.04e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805  66 PLP-NIENGFIRTAGdLRFGSNAEYGCNKGYILVGASQRRCQ----ANKEWSSSQPVCRlQLKCGPPPEIPFAVHDGssF 140
Cdd:PHA02927  87 PSPrDIDNGQLDIGG-VDFGSSITYSCNSGYQLIGESKSYCElgstGSMVWNPEAPICE-SVKCQSPPSISNGRHNG--Y 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 141 SGEYDLDAEVAYNCIPGYHKFNAKGLSISKcllnrknvAQWFGPDlRCKARACPDPgDIENG-LREG--DTFEYPHHVKY 217
Cdd:PHA02927 163 EDFYTDGSVVTYSCNSGYSLIGNSGVLCSG--------GEWSDPP-TCQIVKCPHP-TISNGyLSSGfkRSYSYNDNVDF 232

                        170       180
                 ....*....|....*....|....*....
gi 453232805 218 SCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:PHA02927 233 KCKYGYKLSGSSSSTCSPGNTWQPELPKC 261
PHA02639 PHA02639
EEV host range protein; Provisional
 189-363 9.10e-16

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 78.17  E-value: 9.10e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 189 KARACPDPGDIENGL--REGDTFEYPHHVKYSCNPGFLLVGSTSRQC---SSNGEWTNEPANCKATECSRPSSPLHGKVV 263
Cdd:PHA02639  18 KSIYCDKPDDISNGFitELMEKYEIGKLIEYTCNTDYALIGDRFRTCikdKNNAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 264 GSSLTYQ--SVVTYSCDH----GYRLVGQVQRICLAEGIWGGNEPRCEEIRCSvLPTLPNGYIEGSETS----FGAVAVF 333
Cdd:PHA02639  98 NKREMYKvgDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCR-FPALQNGYINGIPSNkkfyYKTRVGF 176

                        170       180       190
                 ....*....|....*....|....*....|
gi 453232805 334 RCLETMTHEGASKAKCMEDGQWSAPIPRCL 363
Cdd:PHA02639 177 SCKSGFDLVGEKYSTCNINATWFPSIPTCV 206
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 193-247 1.13e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 62.87  E-value: 1.13e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805 193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANCK 247
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYSYgsTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 64-119 5.94e-12

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 60.94  E-value: 5.94e-12
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805  64 CHPLPNIENGFIRTA-GDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVCR 119
Cdd:cd00033    1 CPPPPVPENGTVTGSkGSYSYGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 64-118 1.33e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 59.85  E-value: 1.33e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805    64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:smart00032   1 CPPPPDIENGTVTsSSGTYSYGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 251-305 1.56e-11

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 59.78  E-value: 1.56e-11
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805 251 CSRPSSPLHGKVVGSSLTY--QSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRCE 305
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTCE 57
PHA02831 PHA02831
EEV host range protein; Provisional
 205-363 1.95e-11

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 65.01  E-value: 1.95e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 205 EGDTFEYPHHVKYSCNPGFLLVGSTSrqcsSNGEWTNEPANCKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCD---- 278
Cdd:PHA02831  36 ENKVYEENENLEYKCNNNFDKVFVTC----NNGSWSTKNMCIGKRNCKDPVTILNGYIKNKKDQYSfgDSVTYACKvnkl 111

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 279 HGYRLVGQVQRICLaEGIWGGNEPRCEEIRCSvLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWS 356
Cdd:PHA02831 112 EKYSIVGNETVKCI-NKQWVPKYPVCKLIRCK-YPALQNGFLNVFEKKFyyGDIVNFKCKKGFILLGSSVSTCDINSIWY 189


                 ....*..
gi 453232805 357 APIPRCL 363
Cdd:PHA02831 190 PGIPKCV 196
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 193-246 7.24e-11

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 57.92  E-value: 7.24e-11
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   193 CPDPGDIENGLREGDTFEYPH--HVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSYgdTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 251-304 6.35e-10

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 55.23  E-value: 6.35e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   251 CSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYSygDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 206-483 2.47e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.51  E-value: 2.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 206 GDTFEYphhvkySCNPGF--LLVGSTSRQCSSNGeWT--NEpanCKATECSRPSSPLHGKVVGSSLTYQSVVTYSCDHGY 281
Cdd:PHA02927  47 GDTIEY------LCLPGYrkQKMGPIYAKCTGTG-WTlfNQ---CIKRRCPSPRDIDNGQLDIGGVDFGSSITYSCNSGY 116

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 282 RLVGQVQRIC----LAEGIWGGNEPRCEEIRCSVLPTLPNGYIEGSETSFgavavfrcletmthegaskakcmedgqwsa 357
Cdd:PHA02927 117 QLIGESKSYCelgsTGSMVWNPEAPICESVKCQSPPSISNGRHNGYEDFY------------------------------ 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 358 piprclascrvphiqngkirdksegqliASGSKVIVECNKQHEANIDERLICSNSTWSHVPVCSPLSChnwpprvPHARI 437
Cdd:PHA02927 167 ----------------------------TDGSVVTYSCNSGYSLIGNSGVLCSGGEWSDPPTCQIVKC-------PHPTI 211

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*.
gi 453232805 438 LFSKSSHGSIAKYECNngyhpnrNNQIIKCLYGEWTKDGPPMKCLP 483
Cdd:PHA02927 212 SNGYLSSGFKRSYSYN-------DNVDFKCKYGYKLSGSSSSTCSP 250
PHA02927 PHA02927
secreted complement-binding protein; Provisional
 377-557 3.34e-09

secreted complement-binding protein; Provisional


Pssm-ID: 222943 [Multi-domain]  Cd Length: 263  Bit Score: 58.13  E-value: 3.34e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 377 RDKSEGQL----IASGSKVIVECNKQHEANIDERLICS-NSTWSHV-----PVCSPLSCHNwPPRVPHARILFSKS--SH 444
Cdd:PHA02927  90 RDIDNGQLdiggVDFGSSITYSCNSGYQLIGESKSYCElGSTGSMVwnpeaPICESVKCQS-PPSISNGRHNGYEDfyTD 168

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 445 GSIAKYECNNGYHPNRNNQIIkCLYGEWTKdgpPMKCLPSWCEHPSKTYGTLPGGqillegilgayefqsYIQKVEEGRA 524
Cdd:PHA02927 169 GSVVTYSCNSGYSLIGNSGVL-CSGGEWSD---PPTCQIVKCPHPTISNGYLSSG---------------FKRSYSYNDN 229

                        170       180       190
                 ....*....|....*....|....*....|....
gi 453232805 525 ISFQCGKGNYLIGPPKATCVNGE-WMPKVsPKCV 557
Cdd:PHA02927 230 VDFKCKYGYKLSGSSSSTCSPGNtWQPEL-PKCV 262
Sushi pfam00084
Sushi repeat (SCR repeat);
309-362 3.48e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 52.89  E-value: 3.48e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805  309 CSVLPTLPNGYIEGS--ETSFGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:pfam00084   1 CPPPPDIPNGKVSATknEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 64-246 6.40e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 57.75  E-value: 6.40e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805  64 CHPLPNIENGFIRTAGD-LRFGSNAEYGCNKGYILVGASQRRC---QANKEWSSSQPVCRLQlKCGPPPEIPfavhDGSS 139
Cdd:PHA02639  22 CDKPDDISNGFITELMEkYEIGKLIEYTCNTDYALIGDRFRTCikdKNNAIWSNKAPFCMLK-ECNDPPSII----NGKI 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 140 FSGE--YDLDAEVAYNCipGYHK---FNAKGLSISKCLLNRknvaQWFGPDLRCKARACPDPG---DIENGLREGDTFEY 211
Cdd:PHA02639  97 YNKRemYKVGDEIYYVC--NEHKgvqYSLVGNEKITCIQDK----SWKPDPPICKMINCRFPAlqnGYINGIPSNKKFYY 170

                        170       180       190
                 ....*....|....*....|....*....|....*
gi 453232805 212 PHHVKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:PHA02639 171 KTRVGFSCKSGFDLVGEKYSTCNINATWFPSIPTC 205
Sushi pfam00084
Sushi repeat (SCR repeat);
251-304 8.41e-09

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 51.73  E-value: 8.41e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805  251 CSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNygASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 143-304 9.03e-09

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 56.98  E-value: 9.03e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 143 EYDLDAEVAYNCIPGYHKFnakGLSISKCLLNRKNvAQWFGPDLRCKARACPDPGDIENG--LREGDTFEYPHHVKYSCN 220
Cdd:PHA02639  39 KYEIGKLIEYTCNTDYALI---GDRFRTCIKDKNN-AIWSNKAPFCMLKECNDPPSIINGkiYNKREMYKVGDEIYYVCN 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 221 P----GFLLVGSTSRQCSSNGEWTNEPANCKATECSRPS---SPLHGKVVGSSLTYQSVVTYSCDHGYRLVGQVQRICLA 293
Cdd:PHA02639 115 EhkgvQYSLVGNEKITCIQDKSWKPDPPICKMINCRFPAlqnGYINGIPSNKKFYYKTRVGFSCKSGFDLVGEKYSTCNI 194

                        170
                 ....*....|.
gi 453232805 294 EGIWGGNEPRC 304
Cdd:PHA02639 195 NATWFPSIPTC 205
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 309-362 1.27e-08

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 51.31  E-value: 1.27e-08
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805 309 CSVLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:cd00033    1 CPPPPVPENGTVTGSKGSYsyGSTVTYSCNEGYTLVGSSTITCTENGGWSPPPPTC 56
PHA02639 PHA02639
EEV host range protein; Provisional
 247-420 1.57e-08

EEV host range protein; Provisional


Pssm-ID: 165022 [Multi-domain]  Cd Length: 295  Bit Score: 56.60  E-value: 1.57e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 247 KATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHGYRLVGQVQRICLAE---GIWGGNEPRCEEIRCSVLPTLPNGYIE 321
Cdd:PHA02639  18 KSIYCDKPDDISNGFITELMEKYEigKLIEYTCNTDYALIGDRFRTCIKDknnAIWSNKAPFCMLKECNDPPSIINGKIY 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 322 GSETSF--GAVAVFRCLE----TMTHEGASKAKCMEDGQWSAPIPRC-LASCRVPHIQNGKIRDKSEGQLIASGSKVIVE 394
Cdd:PHA02639  98 NKREMYkvGDEIYYVCNEhkgvQYSLVGNEKITCIQDKSWKPDPPICkMINCRFPALQNGYINGIPSNKKFYYKTRVGFS 177

                        170       180
                 ....*....|....*....|....*...
gi 453232805 395 CNKQHEANIDERLICS-NSTW-SHVPVC 420
Cdd:PHA02639 178 CKSGFDLVGEKYSTCNiNATWfPSIPTC 205
Sushi pfam00084
Sushi repeat (SCR repeat);
193-246 1.86e-08

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 50.96  E-value: 1.86e-08
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805  193 CPDPGDIENGLREGDTFEYPHH--VKYSCNPGFLLVGSTSRQCSSNGEWTNEPANC 246
Cdd:pfam00084   1 CPPPPDIPNGKVSATKNEYNYGasVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 309-362 2.16e-08

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 50.60  E-value: 2.16e-08
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   309 CSVLPTLPNGYIEGSETSF--GAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:smart00032   1 CPPPPDIENGTVTSSSGTYsyGDTVTYSCDPGYTLIGSSTITCLENGTWSPPPPTC 56
Sushi pfam00084
Sushi repeat (SCR repeat);
64-118 1.82e-07

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 48.26  E-value: 1.82e-07
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 453232805   64 CHPLPNIENGFIR-TAGDLRFGSNAEYGCNKGYILVGASQRRCQANKEWSSSQPVC 118
Cdd:pfam00084   1 CPPPPDIPNGKVSaTKNEYNYGASVSYECDPGYRLVGSPTITCQEDGTWSPPFPEC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 234-365 1.97e-07

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 53.17  E-value: 1.97e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 234 SSNGEWtNEPANCKATECsRPSSPLHGKV--VGSSLTYQSVVTYSCDHGYRLVGQVQRICLAEGiWgGNEPRCEEiRCSv 311
Cdd:PHA02954 114 NGNTSW-NDTVTCPNAEC-QPLQLEHGSCqpVKEKYSFGEHITINCDVGYEVIGASYISCTANS-W-NVIPSCQQ-KCD- 187

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 453232805 312 LPTLPNGYIEGSETSFGAVAVFRCLETMTHEGASKAKCMeDGQWSAPIPRCLAS 365
Cdd:PHA02954 188 IPSLSNGLISGSTFSIGGVIHLSCKSGFTLTGSPSSTCI-DGKWNPVLPICVRS 240
PHA02831 PHA02831
EEV host range protein; Provisional
 177-304 4.45e-07

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 51.53  E-value: 4.45e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 177 NVAQWFGPDLRCKARACPDPGDIENGL--REGDTFEYPHHVKYSCNPGFL----LVGSTSRQCSsNGEWTNEPANCKATE 250
Cdd:PHA02831  62 NNGSWSTKNMCIGKRNCKDPVTILNGYikNKKDQYSFGDSVTYACKVNKLekysIVGNETVKCI-NKQWVPKYPVCKLIR 140

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 453232805 251 CSRPSspLHGKVVGS---SLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:PHA02831 141 CKYPA--LQNGFLNVfekKFYYGDIVNFKCKKGFILLGSSVSTCDINSIWYPGIPKC 195
PHA02817 PHA02817
EEV Host range protein; Provisional
 246-362 5.46e-07

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 51.09  E-value: 5.46e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 246 CKATECSRPSSPLHGKVVGSSLTYQ--SVVTYSCDHG-----YRLVGQVQRICLAEGIWGGNEPRCEEIRCSvLPTLPNG 318
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNigSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCR-FPALQNG 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 453232805 319 YIEGSETS----FGAVAVFRCLETMTHEGASKAKCMEDGQWSAPIPRC 362
Cdd:PHA02817  98 FVNGIPDSkkfyYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
PHA02831 PHA02831
EEV host range protein; Provisional
 407-571 1.15e-06

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 50.38  E-value: 1.15e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 407 LICSNSTWSHVPVC-SPLSCHNwPPRVPHARILFSKS--SHGSIAKYECNNG---YHPNRNNQIIKCLYGEWTKDGPPMK 480
Cdd:PHA02831  59 VTCNNGSWSTKNMCiGKRNCKD-PVTILNGYIKNKKDqySFGDSVTYACKVNkleKYSIVGNETVKCINKQWVPKYPVCK 137

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 481 CLPswCEHPSktygtlpggqiLLEGILGAYEFQSYIqkveeGRAISFQCGKGNYLIGPPKATC-VNGEWMPKVsPKCVS- 558
Cdd:PHA02831 138 LIR--CKYPA-----------LQNGFLNVFEKKFYY-----GDIVNFKCKKGFILLGSSVSTCdINSIWYPGI-PKCVKd 198

                        170
                 ....*....|...
gi 453232805 559 QTHPMIEGKILWD 571
Cdd:PHA02831 199 KVHNEIQPNYLFD 211
PHA02817 PHA02817
EEV Host range protein; Provisional
 304-421 1.87e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 49.17  E-value: 1.87e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 304 CEEIRCSVLPTLPNGYI--EGSETSFGAVAVFRCLETM-----THEGASKAKCMEDGQWSAPIPRC-LASCRVPHIQNGK 375
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIynKKTEYNIGSNVTFFCGNNTrgvryTLVGEKNIICEKDGKWNKEFPVCkIIRCRFPALQNGF 98

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 453232805 376 IRDKSEGQLIASGSKVIVECNKQHEANIDERLICS-NSTW-SHVPVCS 421
Cdd:PHA02817  99 VNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGiNSSWiPKVPICS 146
PHA02817 PHA02817
EEV Host range protein; Provisional
 188-304 5.10e-06

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 48.01  E-value: 5.10e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 188 CKARACPDPGDIENGLREGDTFEYP--HHVKYSCNPG-----FLLVGSTSRQCSSNGEWTNEPANCKATECSRPSSPlHG 260
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKTEYNigSNVTFFCGNNtrgvrYTLVGEKNIICEKDGKWNKEFPVCKIIRCRFPALQ-NG 97

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 453232805 261 KVVG----SSLTYQSVVTYSCDHGYRLVGQVQRICLAEGIWGGNEPRC 304
Cdd:PHA02817  98 FVNGipdsKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSWIPKVPIC 145
PHA02817 PHA02817
EEV Host range protein; Provisional
 118-239 1.30e-04

EEV Host range protein; Provisional


Pssm-ID: 165167 [Multi-domain]  Cd Length: 225  Bit Score: 43.78  E-value: 1.30e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 118 CRLQLKCGPPPEIPFAVHDGSSfsgEYDLDAEVAYNCipgyhKFNAKGLSISkcLLNRKNV-----AQWFGPDLRCKARA 192
Cdd:PHA02817  19 CDLNKCCYPPSIKNGYIYNKKT---EYNIGSNVTFFC-----GNNTRGVRYT--LVGEKNIicekdGKWNKEFPVCKIIR 88

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 453232805 193 CPDPG---DIENGLREGDTFEYPHHVKYSCNPGFLLVGSTSRQCSSNGEW 239
Cdd:PHA02817  89 CRFPAlqnGFVNGIPDSKKFYYESEVSFSCKPGFVLIGTKYSVCGINSSW 138
CCP cd00033
Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) ...
 425-481 1.89e-04

Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system; SUSHI repeats (short complement-like repeat, SCR) are abundant in complement control proteins. The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. Typically, 2 to 4 modules contribute to a binding site, implying that the orientation of the modules to each other is critical for function.


Pssm-ID: 153056 [Multi-domain]  Cd Length: 57  Bit Score: 39.75  E-value: 1.89e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPnRNNQIIKCL-YGEWTkdGPPMKC 481
Cdd:cd00033    1 CPP-PPVPENGTVTGSKGsySYGSTVTYSCNEGYTL-VGSSTITCTeNGGWS--PPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 309-557 8.66e-04

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 42.00  E-value: 8.66e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 309 CSVlPTLPNGYIEGSETSFG--AVAVFRClETMTHEGASKAKCMEDgQWSAPIP---RCLASCRVPHIQNGKIRD-KSEG 382
Cdd:PHA02954  21 CTV-PTMNNAKLTSTETSFNdkQKVTFTC-DSGYYSLDPNAVCETD-KWKYENPckkMCTVSDYVSELYDKPLYEvNSTI 97

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 383 QLIASGSKVIVECNKQHeaniderlicSNSTWSHVPVCSPLSCHNWPPRVPHARILFSKSSHGSIAKYECNNGYHPnRNN 462
Cdd:PHA02954  98 TLICKDETKYFRCEEKN----------GNTSWNDTVTCPNAECQPLQLEHGSCQPVKEKYSFGEHITINCDVGYEV-IGA 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 463 QIIKCLYGEWTkdgppmkCLPSW---CEHPSKTYGTLPGGQILLEGIlgayefqsyiqkveegraISFQCGKGNYLIGPP 539
Cdd:PHA02954 167 SYISCTANSWN-------VIPSCqqkCDIPSLSNGLISGSTFSIGGV------------------IHLSCKSGFTLTGSP 221

                        250
                 ....*....|....*...
gi 453232805 540 KATCVNGEWMPkVSPKCV 557
Cdd:PHA02954 222 SSTCIDGKWNP-VLPICV 238
PHA02831 PHA02831
EEV host range protein; Provisional
 48-174 1.66e-03

EEV host range protein; Provisional


Pssm-ID: 165176 [Multi-domain]  Cd Length: 268  Bit Score: 40.75  E-value: 1.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805  48 MCDGEcgLSCVNPIAmchplpnIENGFIRTAGD-LRFGSNAEYGC--NK--GYILVGASQRRCqANKEWSSSQPVCRLqL 122
Cdd:PHA02831  71 MCIGK--RNCKDPVT-------ILNGYIKNKKDqYSFGDSVTYACkvNKleKYSIVGNETVKC-INKQWVPKYPVCKL-I 139

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 453232805 123 KCGPPpeipfAVHDG--SSFSGEYDLDAEVAYNCIPGyhkFNAKGLSISKCLLN 174
Cdd:PHA02831 140 RCKYP-----ALQNGflNVFEKKFYYGDIVNFKCKKG---FILLGSSVSTCDIN 185
CCP smart00032
Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat ...
 425-481 2.52e-03

Domain abundant in complement control proteins; SUSHI repeat; short complement-like repeat (SCR); The complement control protein (CCP) modules (also known as short consensus repeats SCRs or SUSHI repeats) contain approximately 60 amino acid residues and have been identified in several proteins of the complement system. A missense mutation in seventh CCP domain causes deficiency of the b subunit of factor XIII.


Pssm-ID: 214478 [Multi-domain]  Cd Length: 56  Bit Score: 36.35  E-value: 2.52e-03
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805   425 CHNwPPRVPHARILFSKS--SHGSIAKYECNNGYHPNRNNqIIKCL-YGEWTkdGPPMKC 481
Cdd:smart00032   1 CPP-PPDIENGTVTSSSGtySYGDTVTYSCDPGYTLIGSS-TITCLeNGTWS--PPPPTC 56
PHA02954 PHA02954
EEV membrane glycoprotein; Provisional
 207-304 3.63e-03

EEV membrane glycoprotein; Provisional


Pssm-ID: 165263 [Multi-domain]  Cd Length: 317  Bit Score: 40.07  E-value: 3.63e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 453232805 207 DTFEYPHHVKYSCNPGFLLVGSTSRQCSSNgEWTNEPAnCKaTECSRPSSPlHGKVVGSSLTYQSVVTYSCDHGYRLVGQ 286
Cdd:PHA02954 145 EKYSFGEHITINCDVGYEVIGASYISCTAN-SWNVIPS-CQ-QKCDIPSLS-NGLISGSTFSIGGVIHLSCKSGFTLTGS 220

                         90
                 ....*....|....*...
gi 453232805 287 VQRICLaEGIWGGNEPRC 304
Cdd:PHA02954 221 PSSTCI-DGKWNPVLPIC 237
Sushi pfam00084
Sushi repeat (SCR repeat);
520-556 8.62e-03

Sushi repeat (SCR repeat);


Pssm-ID: 459664 [Multi-domain]  Cd Length: 56  Bit Score: 34.78  E-value: 8.62e-03
                          10        20        30
                  ....*....|....*....|....*....|....*...
gi 453232805  520 EEGRAISFQCGKGNYLIGPPKATCV-NGEWMPKVsPKC 556
Cdd:pfam00084  20 NYGASVSYECDPGYRLVGSPTITCQeDGTWSPPF-PEC 56
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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