|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
5-963 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1164.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 5 TAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMSKWVRVANTQKCIRAGGKHNDL 84
Cdd:PLN02900 12 PGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 85 DDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDAAsgLEPDLECKQMWLDLgLKPEH 164
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 165 ILPGSMKDNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFE 244
Cdd:PLN02900 169 VLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 245 RLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVLR 324
Cdd:PLN02900 249 RLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLR 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 325 RILRRAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIE--KLGNQ 402
Cdd:PLN02900 329 RLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAaaKANGG 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 403 TTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQ-GKGASKIEEINLDVHAISQLQEQGVPPTN 481
Cdd:PLN02900 409 PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRaAHLKAGGGAIELAAEATSWLQKQGVAATD 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 482 DTFKYKYEAVSDerdsaynygvcnSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALVKVNDEAneFL 561
Cdd:PLN02900 489 DFLKYDWLSDHE------------AVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV--VE 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 562 VDRVYNRGGYILHIGVV-EGTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNS 640
Cdd:PLN02900 555 VSDVQKAGGFVLHIGTVtEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSH 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 641 KAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDPVRVISfgvpvdeleqnpdseAGEQTSV 720
Cdd:PLN02900 635 GKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVS---------------VGGVYSM 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 721 EFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIvrlkatidnDKSGKDSKSHV-KEIVE 799
Cdd:PLN02900 700 ELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLEREL---------DSALKVEGSDLeKKVAS 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 800 LTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVSVTVVERAKTLCEA--NPNATVLVEQLEAFNNTKALDAAL 877
Cdd:PLN02900 771 LKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKalSAGKSVLVARLDVGVDAAALKEAA 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 878 KQVRSQLPDAAAMFLSVDADSKKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQLA 957
Cdd:PLN02900 851 EKVIAKLGDPAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
....*.
gi 24582809 958 SKFAQS 963
Cdd:PLN02900 931 RAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-965 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1008.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 4 LTAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPnsemsKWVRVANTQKCIRAGGKHND 83
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHND 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 84 LDDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFggdaasglEPDLECKQMWLDL-GLKP 162
Cdd:COG0013 77 LENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVY--------EDDDEAYDIWKKEiGVPE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 163 EHILPGSMKDNFWEMGETGPCGPCSELHFDR---IGGrSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDC 239
Cdd:COG0013 149 ERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 240 GMGFERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAppyqgRVGADDVDgiDMAYRVLADHARTITIALADGGTPDNTGR 319
Cdd:COG0013 228 GMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGV-----KYGADEED--DVSLRVIADHIRAVAFLIADGVLPSNEGR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 320 GYVLRRILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKL 399
Cdd:COG0013 301 GYVLRRILRRAVRHG-RLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 400 --GNQTTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAA----KHNSYVLSQGKGASKIEEINLDVHAIsqlq 473
Cdd:COG0013 380 kaAGGKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAmeeqRERARAAAKFSGDAAVDGVWRELLEE---- 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 474 eqgVPPTndTFKyKYEAVSDErdsaynygvcnSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALvkV 553
Cdd:COG0013 456 ---GGPT--EFV-GYDTLEAE-----------AKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTI--E 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 554 NDEAnEFLVDRVY-NRGGYILHIG-VVEGTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVP 631
Cdd:COG0013 517 GDGG-VFEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAP 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 632 EKLRFDFNSKAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKiRGLRSVFDEVYPDPVRVISFGvpvdeleqnpd 711
Cdd:COG0013 596 DRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG----------- 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 712 seageQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIV-RLKATidndksgkds 790
Cdd:COG0013 664 -----DFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELAeLLKAP---------- 728
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 791 kshVKEIVELTEQIshatipyvkKDEmrnlLKGLKKTLDDKERALRAAVSVTVVERAKTLCEANpnatVLVEQLEAFNNt 870
Cdd:COG0013 729 ---PEELPERVEAL---------LEE----LKELEKELEQLKAKLASAAADDLLAQAEEIGGVK----VLAARVEGVDA- 787
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 871 KALDAALKQVRSQLPDAAAMFLSVDADskKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKV 950
Cdd:COG0013 788 KDLRDLADDLKDKLGSGVVVLASVADG--KVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKL 865
|
970
....*....|....*
gi 24582809 951 DEIVQLASKFAQSKL 965
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-944 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 822.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 8 EVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEmskwvRVANTQKCIRAggkhNDLDDV 87
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSN-----RLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 88 GKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFggdaasglEPDLECKQMWLDLGLKPEHILP 167
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVY--------EDDEEAYKIWEKIGIPADRIIK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 168 GSMKDNFWEMGEtGPCGPCSELHFDRIGGRsvPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFERLV 247
Cdd:TIGR00344 144 CDAKDNFWDMGD-GPCGPCTEIYYDFVGGK--PGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 248 SVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDGID--MAYRVLADHARTITIALADGGTPDNTGRGYVLRR 325
Cdd:TIGR00344 221 AVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 326 ILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNqTTI 405
Cdd:TIGR00344 301 LIRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGK-KEL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 406 PGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQgkgasKIEEINLDVHAISQlqeqgVPPTNDTFK 485
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSK-----QNSQFQEQEIALVN-----VYPATEFLG 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 486 YKYEAvsderdsaynygvCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALVKvndEANEFLVDRV 565
Cdd:TIGR00344 449 YDDLE-------------FEAKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA---NDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 566 YNRGGYILHIGVVE-GTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAM 644
Cdd:TIGR00344 513 QKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 645 TIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRsVFDEVYP--DPVRVISFGvpvDEleqnpdseageqtSVEF 722
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFA-LFGEKYVpgEKVRVVSVG---DF-------------SVEL 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 723 CGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAfeqeivRLKATIdnDKSGKDSKSHVKEIVELTE 802
Cdd:TIGR00344 656 CGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQED------KLKELA--DILKVTPNELPKKVERFFE 727
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 803 QishatipyvkkdemrnlLKGLKKTLDDKERALRAAVSVTVVERAKTLceanPNATVLVEQLEAfNNTKALDAALKQVRS 882
Cdd:TIGR00344 728 E-----------------WKALQKELESLKLKIADQKIDELKDKAETI----NGVKVLVEVVDA-KDMKSLKTMADRLKS 785
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24582809 883 QLPDAAAMFLSVDADskKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASG 944
Cdd:TIGR00344 786 KLGSAIYVLASFAEG--KVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-596 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 780.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 8 EVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADpnseMSKWVRVANTQKCIRAGgkhnDLDDV 87
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVA----KPPYNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 88 GKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDAasglepdlECKQMWLDL-GLKPEHIL 166
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERIL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 167 PGSMKDNFWEMGETGPCGPCSELHFDR---IGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGF 243
Cdd:pfam01411 145 RFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 244 ERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQgrvgaddVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVL 323
Cdd:pfam01411 225 ERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 324 RRILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNQ- 402
Cdd:pfam01411 298 RRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGk 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 403 TTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSqgKGASKIEEINLDVHAISQLqeqgvPPTND 482
Cdd:pfam01411 377 KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERS--KQAVKEKGEKLDVSALKEL-----PATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 483 TFKykyeavsderdsaYNYGVCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGalvKVNDEANEFLV 562
Cdd:pfam01411 450 FLG-------------YDDLESEAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTG---YIIGDGGEFRV 513
|
570 580 590
....*....|....*....|....*....|....*
gi 24582809 563 DRVYNRGGYILHIGVVE-GTLKVGDELELHIDVER 596
Cdd:pfam01411 514 TDVQKYGGVVVHKGKLEsGKLKVGDKVIAVIDEDR 548
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-253 |
6.00e-131 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 393.65 E-value: 6.00e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 6 AKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEmskwvRVANTQKCIRAGGKHNdld 85
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPAN-----RLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 86 dVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDaasglepDLECKQMWLDLGLKPEHI 165
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 166 LPGSMKDNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFER 245
Cdd:cd00673 145 ERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLER 224
|
....*...
gi 24582809 246 LVSVIQNK 253
Cdd:cd00673 225 LVWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
694-752 |
1.69e-10 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 56.62 E-value: 1.69e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 24582809 694 VRVISFGvpvdeleqnpdseageQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRI 752
Cdd:smart00863 1 VRVVSIG----------------DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
5-963 |
0e+00 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 1164.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 5 TAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMSKWVRVANTQKCIRAGGKHNDL 84
Cdd:PLN02900 12 PGDRIRRTFLSFFESKGHTFLPSSPLVPVDDPTLLFTNAGMNQFKPIFLGTADPNTPLRKLPRATNTQKCIRAGGKHNDL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 85 DDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDAAsgLEPDLECKQMWLDLgLKPEH 164
Cdd:PLN02900 92 DDVGKDTYHHTFFEMLGNWSFGDYFKKEAIGWAWELLTKVYGLPADRLYATYFGGDEK--QAPDDEARAIWLDY-LPEER 168
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 165 ILPGSMKDNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFE 244
Cdd:PLN02900 169 VLPFGCKDNFWEMGDTGPCGPCSEIHYDRIGERDAADLVNNDDPRFIEIWNLVFIQFNREADGSLKPLPAKHVDTGMGLE 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 245 RLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVLR 324
Cdd:PLN02900 249 RLASILQNKPSNYDTDLFMPIFDAIQEATGARPYAGKVGAEDDDRVDMAYRVVADHIRTLSFAIADGVVPSNEGRGYVLR 328
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 325 RILRRAVRYATEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIE--KLGNQ 402
Cdd:PLN02900 329 RLLRRAVRYGRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEKGIEKFKKALAaaKANGG 408
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 403 TTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQ-GKGASKIEEINLDVHAISQLQEQGVPPTN 481
Cdd:PLN02900 409 PVLSGKDAFLLYDTYGFPVDLTELMAEERGVTVDMEGFEAAMEEARERSRaAHLKAGGGAIELAAEATSWLQKQGVAATD 488
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 482 DTFKYKYEAVSDerdsaynygvcnSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALVKVNDEAneFL 561
Cdd:PLN02900 489 DFLKYDWLSDHE------------AVVKAILTGGGFVESVSEGDEVGIVLDKTSFYAESGGQIGDTGVLEGSGGAV--VE 554
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 562 VDRVYNRGGYILHIGVV-EGTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNS 640
Cdd:PLN02900 555 VSDVQKAGGFVLHIGTVtEGSVSVGDAVTCKVDYDRRRRIAPNHTATHLLNSALKEVLGDHVDQKGSLVAFEKLRFDFSH 634
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 641 KAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRSVFDEVYPDPVRVISfgvpvdeleqnpdseAGEQTSV 720
Cdd:PLN02900 635 GKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRINGLRAVFGEKYPDPVRVVS---------------VGGVYSM 699
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 721 EFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIvrlkatidnDKSGKDSKSHV-KEIVE 799
Cdd:PLN02900 700 ELCGGTHVSNTAEAEAFKLLSEEGIAKGIRRITAVTGGAAVEAINAADSLEREL---------DSALKVEGSDLeKKVAS 770
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 800 LTEQISHATIPYVKKDEMRNLLKGLKKTLDDKERALRAAVSVTVVERAKTLCEA--NPNATVLVEQLEAFNNTKALDAAL 877
Cdd:PLN02900 771 LKSRVDAAVIPAAKKEEIRARVSALQKELRAAQKEAAALRAKLAVAKATELASKalSAGKSVLVARLDVGVDAAALKEAA 850
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 878 KQVRSQLPDAAAMFLSVDADSKKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKVDEIVQLA 957
Cdd:PLN02900 851 EKVIAKLGDPAAVVLSSDEEKGKVSLVAAVPPGVVKKGLKAGKWLGAIAKLCGGGGGGKPGFAQGQGRDAEKLDAALEKA 930
|
....*.
gi 24582809 958 SKFAQS 963
Cdd:PLN02900 931 RAFAVA 936
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
4-965 |
0e+00 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 1008.82 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 4 LTAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPnsemsKWVRVANTQKCIRAGGKHND 83
Cdd:COG0013 2 MTSAEIRQKFLDFFESKGHTIVPSSSLVPKNDPTLLFTNAGMVQFKPYFLGQEKP-----PYPRATTSQKCVRTGGKHND 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 84 LDDVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFggdaasglEPDLECKQMWLDL-GLKP 162
Cdd:COG0013 77 LENVGYTARHHTFFEMLGNFSFGDYFKEEAIAWAWELLTEVLGLPKERLWVTVY--------EDDDEAYDIWKKEiGVPE 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 163 EHILPGSMKDNFWEMGETGPCGPCSELHFDR---IGGrSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDC 239
Cdd:COG0013 149 ERIIRLGKKDNFWEMGDTGPCGPCSEIFYDRgpeYGG-GPPGSPGEDGDRYIEIWNLVFMQFNRDEDGTLTPLPKKNIDT 227
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 240 GMGFERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAppyqgRVGADDVDgiDMAYRVLADHARTITIALADGGTPDNTGR 319
Cdd:COG0013 228 GMGLERIAAVLQGVHSNYETDLFRPLIEAAAELTGV-----KYGADEED--DVSLRVIADHIRAVAFLIADGVLPSNEGR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 320 GYVLRRILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKL 399
Cdd:COG0013 301 GYVLRRILRRAVRHG-RLLGIKEPFLYKLVPVVVEEMGDAYPELKEKQELIEKVLKAEEERFLRTLERGLKLLDEAIAKL 379
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 400 --GNQTTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAA----KHNSYVLSQGKGASKIEEINLDVHAIsqlq 473
Cdd:COG0013 380 kaAGGKVLSGEDAFKLYDTYGFPLDLTEEIARERGLTVDEEGFEAAmeeqRERARAAAKFSGDAAVDGVWRELLEE---- 455
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 474 eqgVPPTndTFKyKYEAVSDErdsaynygvcnSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALvkV 553
Cdd:COG0013 456 ---GGPT--EFV-GYDTLEAE-----------AKVLALVKDGELVDSAKAGEEVEVVLDRTPFYAESGGQVGDTGTI--E 516
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 554 NDEAnEFLVDRVY-NRGGYILHIG-VVEGTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVP 631
Cdd:COG0013 517 GDGG-VFEVTDTQkPPGGLIVHIGkVEEGELKVGDTVTAQVDAERRRAIARNHSATHLLHAALREVLGEHVTQAGSLVAP 595
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 632 EKLRFDFNSKAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKiRGLRSVFDEVYPDPVRVISFGvpvdeleqnpd 711
Cdd:COG0013 596 DRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKA-LGAMALFGEKYGDEVRVVSIG----------- 663
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 712 seageQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAFEQEIV-RLKATidndksgkds 790
Cdd:COG0013 664 -----DFSRELCGGTHVSRTGDIGLFKIVSESSVAAGVRRIEAVTGEAALEYLREQEALLKELAeLLKAP---------- 728
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 791 kshVKEIVELTEQIshatipyvkKDEmrnlLKGLKKTLDDKERALRAAVSVTVVERAKTLCEANpnatVLVEQLEAFNNt 870
Cdd:COG0013 729 ---PEELPERVEAL---------LEE----LKELEKELEQLKAKLASAAADDLLAQAEEIGGVK----VLAARVEGVDA- 787
|
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 871 KALDAALKQVRSQLPDAAAMFLSVDADskKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASGTNYEKV 950
Cdd:COG0013 788 KDLRDLADDLKDKLGSGVVVLASVADG--KVSLVAGVTKDLVKKGLKAGDLVKEVAKIVGGGGGGRPDMAQAGGKDPSKL 865
|
970
....*....|....*
gi 24582809 951 DEIVQLASKFAQSKL 965
Cdd:COG0013 866 DEALAAVKEWLAEKL 880
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
8-944 |
0e+00 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 822.01 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 8 EVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEmskwvRVANTQKCIRAggkhNDLDDV 87
Cdd:TIGR00344 1 EIRQTFLDFFKEKGHQVIPSAPLVPRNDPTLLLTNAGMAQFKPIFTGIVKPPSN-----RLTNAQPCIRL----NDLENV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 88 GKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFggdaasglEPDLECKQMWLDLGLKPEHILP 167
Cdd:TIGR00344 72 GRTARHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLDKERLYVTVY--------EDDEEAYKIWEKIGIPADRIIK 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 168 GSMKDNFWEMGEtGPCGPCSELHFDRIGGRsvPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFERLV 247
Cdd:TIGR00344 144 CDAKDNFWDMGD-GPCGPCTEIYYDFVGGK--PGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNIDTGMGLERFV 220
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 248 SVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQGRVGADDVDGID--MAYRVLADHARTITIALADGGTPDNTGRGYVLRR 325
Cdd:TIGR00344 221 AVLQGVPTNYDTDIFLPLIEKIEEITGVKYDSNNAGIMDEKRVEdlRSLRVIADHTRAIAFMLADGVVPSNEGRGYVLRR 300
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 326 ILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNqTTI 405
Cdd:TIGR00344 301 LIRRALRHG-KKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLLKKTGK-KEL 378
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 406 PGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSQgkgasKIEEINLDVHAISQlqeqgVPPTNDTFK 485
Cdd:TIGR00344 379 DGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSK-----QNSQFQEQEIALVN-----VYPATEFLG 448
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 486 YKYEAvsderdsaynygvCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGALVKvndEANEFLVDRV 565
Cdd:TIGR00344 449 YDDLE-------------FEAKVIGLFDDGYLVEQALAGQSVYVILDQTPFYAESGGQIGDTGYLIA---NDGKFRVVDV 512
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 566 YNRGGYILHIGVVE-GTLKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTEQKGSLVVPEKLRFDFNSKAAM 644
Cdd:TIGR00344 513 QKPNGVVFHFGEVEgGSLKVGDKVIAVIDEKRRFRIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRAL 592
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 645 TIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIRGLRsVFDEVYP--DPVRVISFGvpvDEleqnpdseageqtSVEF 722
Cdd:TIGR00344 593 TREELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFA-LFGEKYVpgEKVRVVSVG---DF-------------SVEL 655
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 723 CGGTHLRRSGHIMDFVISSEEAIAKGIRRIVALTGPEALKALKKSEAfeqeivRLKATIdnDKSGKDSKSHVKEIVELTE 802
Cdd:TIGR00344 656 CGGTHVRNTGEIGLFKIVKESGIAAGVRRIEAVTGEAAIEYLNEQED------KLKELA--DILKVTPNELPKKVERFFE 727
|
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 803 QishatipyvkkdemrnlLKGLKKTLDDKERALRAAVSVTVVERAKTLceanPNATVLVEQLEAfNNTKALDAALKQVRS 882
Cdd:TIGR00344 728 E-----------------WKALQKELESLKLKIADQKIDELKDKAETI----NGVKVLVEVVDA-KDMKSLKTMADRLKS 785
|
890 900 910 920 930 940
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24582809 883 QLPDAAAMFLSVDADskKIFCLSSVPKSAVEKGLKANEWVQHVSATLGGKGGGKPESAQASG 944
Cdd:TIGR00344 786 KLGSAIYVLASFAEG--KVKLVCGVSNDVLTKKIKAGELINQIAQVLGGKGGGRPDFAQGGG 845
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
8-596 |
0e+00 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 780.69 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 8 EVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADpnseMSKWVRVANTQKCIRAGgkhnDLDDV 87
Cdd:pfam01411 1 EIRQTFLDFFEKKGHTRVPSSPVVPRNDPTLLFTNAGMNQFKPIFLGGVA----KPPYNRATNSQKCIRAG----DLENV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 88 GKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDAasglepdlECKQMWLDL-GLKPEHIL 166
Cdd:pfam01411 73 GRTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLTKELGLPPERLYVTVFEWDD--------EAGPIWEKIvGGPEERIL 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 167 PGSMKDNFWEMGETGPCGPCSELHFDR---IGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGF 243
Cdd:pfam01411 145 RFGDKDNFWEMGDTGPCGPCSEIDYDRgeeIGGWDSGGTPTADDDRFLEIWNLVFMQFNRENDGTLKPLPKKSIDTGMGL 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 244 ERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAPPYQgrvgaddVDGIDMAYRVLADHARTITIALADGGTPDNTGRGYVL 323
Cdd:pfam01411 225 ERLVAVLQDVRSNYDTDVFIPVIELIEEISGARYYT-------VDETDEAYRVIADHTRALTFALADGVVPSNEGRGYVL 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 324 RRILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLNRTIEKLGNQ- 402
Cdd:pfam01411 298 RRILRRAVRHA-KKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLIAKLKKGk 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 403 TTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAAKHNSYVLSqgKGASKIEEINLDVHAISQLqeqgvPPTND 482
Cdd:pfam01411 377 KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERS--KQAVKEKGEKLDVSALKEL-----PATTE 449
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 483 TFKykyeavsderdsaYNYGVCNSKIVALRFENQFVNEITSGQKAGIVLDKTNFYAESGGQIYDQGalvKVNDEANEFLV 562
Cdd:pfam01411 450 FLG-------------YDDLESEAKILALPKDGEFVAEVLAGQEGGVILDRTPFYAESGGQIGDTG---YIIGDGGEFRV 513
|
570 580 590
....*....|....*....|....*....|....*
gi 24582809 563 DRVYNRGGYILHIGVVE-GTLKVGDELELHIDVER 596
Cdd:pfam01411 514 TDVQKYGGVVVHKGKLEsGKLKVGDKVIAVIDEDR 548
|
|
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
4-755 |
1.31e-133 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 414.56 E-value: 1.31e-133
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 4 LTAKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEMskwvrVANTQKCIRAGgkhnD 83
Cdd:PRK01584 1 MTLDELRKKYIDFFKSKGHVEIAGKSLIPENDPTVLFTTAGMHPLVPYLLGEPHPSGTR-----LVDVQKCLRTG----D 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 84 LDDVGkDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLT--QRLALPKDRLYVTYFGGDAAsgLEPDLECKQMWLDLGLK 161
Cdd:PRK01584 72 IDEVG-DLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTspDYLNIPKDKLYVTVFEGDEE--IPRDEETASVWESLGIP 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 162 PEHILPGSMKDNFW-EMGETGPCGPCSELHFDRiggrSVPELVNMDDP-----DVLEIWNLVFIQYNRESDGSLKQLPKK 235
Cdd:PRK01584 149 KDRIFYLSREHNWWgPVGETGPCGPDTEIFVDT----GKPKCSVNCRPtcscgKYFEIWNNVFMQYNKDEDGNYEELKRK 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 236 HIDCGMGFERLVSVIQNKRSNYDTDLFVPLFDAIQAGTGAppyqgRVGADDVDgiDMAYRVLADHARTITIALADGGT-- 313
Cdd:PRK01584 225 CVDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKISGK-----IYGQNEED--DRSIRIIADHIRAACFILGDPFVvl 297
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 314 PDNTGRGYVLRRILRRAVRYAtEKLNAKPGFFATLVNTVVDLLGDAFPEVKKDPQHIIDIINEEELQFLKTLTRGRNLLN 393
Cdd:PRK01584 298 PSNVGQGYVLRRLIRRSIRHA-KKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEFI 376
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 394 RTIEKLGNQTTIPGDVAWRLYDTYGFPVDLTQLMAEEKSLKIDMDGYEAA--KHNSyvLSQgKGASKIeeinldvhaisq 471
Cdd:PRK01584 377 KLIPNLGSSKIIPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHfkKHQK--VSK-KGADKV------------ 441
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 472 lqeqgvpptndtFKykyeavsderdsaynygvcnskivalrfenqfvneitsgqkagivldktnfyaesGGqiydqgalv 551
Cdd:PRK01584 442 ------------FK-------------------------------------------------------GG--------- 445
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 552 kvndeanefLVDRVYNrggyilhigvvegtlkvgdelelhidverrwlTMKNHSATHALNHCLLQVLGKDTEQKGSLVVP 631
Cdd:PRK01584 446 ---------LADHSYE--------------------------------TTKLHTATHLLHKALRLVLGDHVRQKGSNITA 484
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 632 EKLRFDFNSKAAMTIEQVSKTEQLTKEMVYKNVPIYAKESKLALAKKIrGLRSVFDEVYPDPVRVISFGvpvdeleqnpd 711
Cdd:PRK01584 485 ERLRFDFSHPEKMTDDEIKKVEDIVNLQIKNDLSVKKEVMSLEEAREK-GAMALFGEKYEDIVKVYEID----------- 552
|
730 740 750 760
....*....|....*....|....*....|....*....|....
gi 24582809 712 seageQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRIVAL 755
Cdd:PRK01584 553 -----GFSKEVCGGPHVENTGELGTFKIQKEQSSSSGVRRIRAI 591
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
6-253 |
6.00e-131 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 393.65 E-value: 6.00e-131
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 6 AKEVRNAYLDFFKEQKHIYVHSSSTIPLDDPTLLFANAGMNQFKPIFLGTADPNSEmskwvRVANTQKCIRAGGKHNdld 85
Cdd:cd00673 1 ASEIRETFLSFFEKKGHTRVPSSPVVPRDDPTLLFTNAGMNQFKPIFLGEVPPPAN-----RLVNSQKCIRAGDIDN--- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 86 dVGKDVYHHTFFEMLGNWSFGDYFKKEICSWAWEFLTQRLALPKDRLYVTYFGGDaasglepDLECKQMWLDLGLKPEHI 165
Cdd:cd00673 73 -VGKTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLTEVLGLPKDRLYVSVFEGD-------DEEEAIWWWKIGLPGIRI 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 166 LPGSMKDNFWEMGETGPCGPCSELHFDRIGGRSVPELVNMDDPDVLEIWNLVFIQYNRESDGSLKQLPKKHIDCGMGFER 245
Cdd:cd00673 145 ERIGFKDNFWEMGGNGPCGPCSEIFYDRGEERDAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPKKIVDTGMGLER 224
|
....*...
gi 24582809 246 LVSVIQNK 253
Cdd:cd00673 225 LVWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
504-753 |
4.36e-28 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 113.75 E-value: 4.36e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 504 CNSKIVALRFENqfvneitsgqkaGIVLDKTNFYAESGGQIYDQGALVKVNDEANeflVDRVYNRGGYILHigVVEGT-- 581
Cdd:COG2872 15 FEATVTAVTEEG------------GVVLDRTAFYPTGGGQPGDTGTLVWDGKEIR---VVDVRKEDGEIVH--VLEGApl 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 582 LKVGDELELHIDVERRWLTMKNHSATHALNHCLLQVLGKDTeqKGSLVVPEKLRFDFNsKAAMTIEQVSKTEQLTKEMVY 661
Cdd:COG2872 78 PEVGDEVTGEIDWERRYRHMRLHTALHLLSAVVYREYGAPV--TGGQIGEDRARIDFD-LPEFDEEDLEEIEAEANELIA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 662 KNVPIYAKESKLALAKKIRGL-RSVFDEVYP--DPVRVISFGvpvdeleqNPDSEAgeqtsvefCGGTHLRRSGHIMDFV 738
Cdd:COG2872 155 ADLPVRIYWITREELEAIPGLvRTMSVLPPPgvGRVRIVEIG--------GVDLQP--------CGGTHVANTGEIGRIK 218
|
250
....*....|....*
gi 24582809 739 ISSEEAIAKGIRRIV 753
Cdd:COG2872 219 ITKIEKKGKGNRRVY 233
|
|
| DHHA1 |
pfam02272 |
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called ... |
815-961 |
4.68e-20 |
|
DHHA1 domain; This domain is often found adjacent to the DHH domain pfam01368 and is called DHHA1 for DHH associated domain. This domain is diagnostic of DHH subfamily 1 members. This domains is also found in alanyl tRNA synthetase, suggesting that this domain may have an RNA binding function. The domain is about 60 residues long and contains a conserved GG motif.
Pssm-ID: 396724 [Multi-domain] Cd Length: 139 Bit Score: 87.11 E-value: 4.68e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 815 DEMRNLLKGLKKTLDDKERALRAAVSVTVVERAKTLCeanpNATVLVEQLEAFNNTKALDAALKQVRSQLPDAAAMFLSV 894
Cdd:pfam02272 2 ESLNEELKELEKELEELKEALALLKAKELLEKAEEIN----GVKVLVAEVGEGWDAGALGIAADRLKKKLGDPVIVLVAK 77
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24582809 895 DaDSKKIFCLSSVPKSaveKGLKANEWVQHVSATLGGKGGGKPeSAQASGTNYEKVDEIVQLASKFA 961
Cdd:pfam02272 78 E-DGDKVKVSARSSKD---KGVDAGELLKEVAAILGGGGGGHD-LAAGAGIDAEKLDEALELLEEAI 139
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
529-626 |
3.90e-12 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 66.64 E-value: 3.90e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24582809 529 IVLDKTNFYAESGGQIYDQGALVKVNDEANeFLVDRVYNRGGYILHIGVVEG-------TLKVGDELELHIDVERRWLTM 601
Cdd:PLN02961 5 LVLDRTIFHPQGGGQPSDTGRIVISGGDTK-FSVQDVRRKDGVVYHYGVFEGsnpesasPFEAGDEVTVTVDESRRKLHS 83
|
90 100
....*....|....*....|....*.
gi 24582809 602 KNHSATHALNHCLLQV-LGKDTEQKG 626
Cdd:PLN02961 84 RLHSAGHLLDVCMARVgLGPLEPGKG 109
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
694-752 |
5.16e-11 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 58.22 E-value: 5.16e-11
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 24582809 694 VRVISFGVpvdeleqnpdseageqTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRI 752
Cdd:pfam07973 1 VRVVSIGD----------------FDVDLCGGTHVPNTGEIGAFKILKGESKNKGLRRI 43
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
694-752 |
1.69e-10 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 56.62 E-value: 1.69e-10
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 24582809 694 VRVISFGvpvdeleqnpdseageQTSVEFCGGTHLRRSGHIMDFVISSEEAIAKGIRRI 752
Cdd:smart00863 1 VRVVSIG----------------DFSVELCGGTHVPNTGEIGAFKILSVSGAYWGLQRI 43
|
|
| |
