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Conserved domains on  [gi|24664355|ref|NP_524073|]
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twin of m4 [Drosophila melanogaster]

Protein Classification

ESM4 domain-containing protein( domain architecture ID 11239993)

ESM4 domain-containing protein

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
ESM4 pfam15952
Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer ...
1-158 4.65e-48

Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer of split M2 and enhancer of split MAlpha. These proteins are part of the Notch signaling pathway.


:

Pssm-ID: 464953  Cd Length: 172  Bit Score: 153.19  E-value: 4.65e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355     1 MSFITREYKFESSKVMEPKSDQHTMAMRSLRKLVKPLLRLVKKKQLLRKTLAEIQNQNavNASLEDMRKDPAAScDNMAN 80
Cdd:pfam15952   1 MCLDTKNLKSTSNTMNENKYNSEKKTSRSMKKVLKPLFRLLKKGGKGRPTLLTLAHPN--NVSLENLTQQQQQE-DNSRN 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355    81 EELEQRLYTDL-----RQCPTNVAMIVQQGQQQSIVPVHPEQ-TFIPVHFARTTSGTFFWTSAEG---------ARQHHE 145
Cdd:pfam15952  78 AELEQQLYAEIveksnQSCGACAHGRNCQHTHHQIVPSSPEEdLYLPVHFARTDNGTFFWTTTQErvdddllhaALCQSF 157
                         170
                  ....*....|....*
gi 24664355   146 QQLRQQF--DRWVQA 158
Cdd:pfam15952 158 SQLPGTQyqDRWVQA 172
 
Name Accession Description Interval E-value
ESM4 pfam15952
Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer ...
1-158 4.65e-48

Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer of split M2 and enhancer of split MAlpha. These proteins are part of the Notch signaling pathway.


Pssm-ID: 464953  Cd Length: 172  Bit Score: 153.19  E-value: 4.65e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355     1 MSFITREYKFESSKVMEPKSDQHTMAMRSLRKLVKPLLRLVKKKQLLRKTLAEIQNQNavNASLEDMRKDPAAScDNMAN 80
Cdd:pfam15952   1 MCLDTKNLKSTSNTMNENKYNSEKKTSRSMKKVLKPLFRLLKKGGKGRPTLLTLAHPN--NVSLENLTQQQQQE-DNSRN 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355    81 EELEQRLYTDL-----RQCPTNVAMIVQQGQQQSIVPVHPEQ-TFIPVHFARTTSGTFFWTSAEG---------ARQHHE 145
Cdd:pfam15952  78 AELEQQLYAEIveksnQSCGACAHGRNCQHTHHQIVPSSPEEdLYLPVHFARTDNGTFFWTTTQErvdddllhaALCQSF 157
                         170
                  ....*....|....*
gi 24664355   146 QQLRQQF--DRWVQA 158
Cdd:pfam15952 158 SQLPGTQyqDRWVQA 172
 
Name Accession Description Interval E-value
ESM4 pfam15952
Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer ...
1-158 4.65e-48

Enhancer of split M4 family; This family of proteins includes enhancer of split M4, enhancer of split M2 and enhancer of split MAlpha. These proteins are part of the Notch signaling pathway.


Pssm-ID: 464953  Cd Length: 172  Bit Score: 153.19  E-value: 4.65e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355     1 MSFITREYKFESSKVMEPKSDQHTMAMRSLRKLVKPLLRLVKKKQLLRKTLAEIQNQNavNASLEDMRKDPAAScDNMAN 80
Cdd:pfam15952   1 MCLDTKNLKSTSNTMNENKYNSEKKTSRSMKKVLKPLFRLLKKGGKGRPTLLTLAHPN--NVSLENLTQQQQQE-DNSRN 77
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24664355    81 EELEQRLYTDL-----RQCPTNVAMIVQQGQQQSIVPVHPEQ-TFIPVHFARTTSGTFFWTSAEG---------ARQHHE 145
Cdd:pfam15952  78 AELEQQLYAEIveksnQSCGACAHGRNCQHTHHQIVPSSPEEdLYLPVHFARTDNGTFFWTTTQErvdddllhaALCQSF 157
                         170
                  ....*....|....*
gi 24664355   146 QQLRQQF--DRWVQA 158
Cdd:pfam15952 158 SQLPGTQyqDRWVQA 172
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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