NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|24644502|ref|NP_524244|]
View 

odorant receptor 83c [Drosophila melanogaster]

Protein Classification

odorant receptor( domain architecture ID 139944)

odorant receptor (OR) found in insects similar to Drosophila ORs, novel seven-transmembrane domain proteins that can signal independently of heterotrimeric G proteins, and which show no obvious sequence homology with G protein-coupled receptors (GPCRs) and display an inverted topology with an intracellular N-terminus and an extracellular C-terminus

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
7tm_6 super family cl20237
7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably ...
 69-387 5.15e-15

7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably drosophila odorant receptors.


The actual alignment was detected with superfamily member pfam02949:

Pssm-ID: 251636  Cd Length: 313  Bit Score: 75.02  E-value: 5.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502    69 LKASLMTGGLFHGLGKFLTCLLKHQDMRRLVLYSQSIYDEYETRGDSY-HRTLNSNIDRLLGIMKIIRNGYVFAFCLMEL 147
Cdd:pfam02949   6 LTNLQVLVTSIVCLFKFLLILLKRKEIVELISLLRELDPRCLEEEEERiFERLVATASRVRFLLFIIYILAYALFCISAL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   148 LPLAMlmyDGTRVTAMQYLIPGL--PLENNYCYVVTYMIQTVTMLVQGVGFYSGDLFVFLGLTQILTFADMLQVKVKELN 225
Cdd:pfam02949  86 VSMVL---SLERGLPLPYYLPFPfdWEASRPPYYIAYIYQVLGMTVTVLQNIGSDSLFCSFLLFLVLHLRLLQLRLERLG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   226 DALEQKAEyralvrvgasidgaENRQRLLlDVIRWHQLFTDYCRAINALYYELIATQ------VLSMALAMMLSFCINLS 299
Cdd:pfam02949 163 LDPELSEE--------------EEYQELR-ECVRDHQRILRLVDELNRIFSVPILVQfllsglVICFLLFNLLFFSGPLQ 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   300 SFHMpsAIFFVVSAYSMSIYCILGTILEFAYDQVYESICNVTWYELSGEQRKLFGFLLRESQYPHNIQILGVMSLSVRTA 379
Cdd:pfam02949 228 GIYY--VLYLLAMLIQLFPYCYYGNELTEASEELANAIYSSNWYDASRRYRRTLLIFIMRAQRPITIKAGGFFPISLPTF 305


                  ....*...
gi 24644502   380 LQIVKLIY 387
Cdd:pfam02949 306 ISILKFAY 313
 
Name Accession Description Interval E-value
7tm_6 pfam02949
7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably ...
 69-387 5.15e-15

7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably drosophila odorant receptors.


Pssm-ID: 251636  Cd Length: 313  Bit Score: 75.02  E-value: 5.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502    69 LKASLMTGGLFHGLGKFLTCLLKHQDMRRLVLYSQSIYDEYETRGDSY-HRTLNSNIDRLLGIMKIIRNGYVFAFCLMEL 147
Cdd:pfam02949   6 LTNLQVLVTSIVCLFKFLLILLKRKEIVELISLLRELDPRCLEEEEERiFERLVATASRVRFLLFIIYILAYALFCISAL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   148 LPLAMlmyDGTRVTAMQYLIPGL--PLENNYCYVVTYMIQTVTMLVQGVGFYSGDLFVFLGLTQILTFADMLQVKVKELN 225
Cdd:pfam02949  86 VSMVL---SLERGLPLPYYLPFPfdWEASRPPYYIAYIYQVLGMTVTVLQNIGSDSLFCSFLLFLVLHLRLLQLRLERLG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   226 DALEQKAEyralvrvgasidgaENRQRLLlDVIRWHQLFTDYCRAINALYYELIATQ------VLSMALAMMLSFCINLS 299
Cdd:pfam02949 163 LDPELSEE--------------EEYQELR-ECVRDHQRILRLVDELNRIFSVPILVQfllsglVICFLLFNLLFFSGPLQ 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   300 SFHMpsAIFFVVSAYSMSIYCILGTILEFAYDQVYESICNVTWYELSGEQRKLFGFLLRESQYPHNIQILGVMSLSVRTA 379
Cdd:pfam02949 228 GIYY--VLYLLAMLIQLFPYCYYGNELTEASEELANAIYSSNWYDASRRYRRTLLIFIMRAQRPITIKAGGFFPISLPTF 305


                  ....*...
gi 24644502   380 LQIVKLIY 387
Cdd:pfam02949 306 ISILKFAY 313
 
Name Accession Description Interval E-value
7tm_6 pfam02949
7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably ...
 69-387 5.15e-15

7tm Odorant receptor; This family is composed of 7 transmembrane receptors, that are probably drosophila odorant receptors.


Pssm-ID: 251636  Cd Length: 313  Bit Score: 75.02  E-value: 5.15e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502    69 LKASLMTGGLFHGLGKFLTCLLKHQDMRRLVLYSQSIYDEYETRGDSY-HRTLNSNIDRLLGIMKIIRNGYVFAFCLMEL 147
Cdd:pfam02949   6 LTNLQVLVTSIVCLFKFLLILLKRKEIVELISLLRELDPRCLEEEEERiFERLVATASRVRFLLFIIYILAYALFCISAL 85

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   148 LPLAMlmyDGTRVTAMQYLIPGL--PLENNYCYVVTYMIQTVTMLVQGVGFYSGDLFVFLGLTQILTFADMLQVKVKELN 225
Cdd:pfam02949  86 VSMVL---SLERGLPLPYYLPFPfdWEASRPPYYIAYIYQVLGMTVTVLQNIGSDSLFCSFLLFLVLHLRLLQLRLERLG 162

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   226 DALEQKAEyralvrvgasidgaENRQRLLlDVIRWHQLFTDYCRAINALYYELIATQ------VLSMALAMMLSFCINLS 299
Cdd:pfam02949 163 LDPELSEE--------------EEYQELR-ECVRDHQRILRLVDELNRIFSVPILVQfllsglVICFLLFNLLFFSGPLQ 227

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24644502   300 SFHMpsAIFFVVSAYSMSIYCILGTILEFAYDQVYESICNVTWYELSGEQRKLFGFLLRESQYPHNIQILGVMSLSVRTA 379
Cdd:pfam02949 228 GIYY--VLYLLAMLIQLFPYCYYGNELTEASEELANAIYSSNWYDASRRYRRTLLIFIMRAQRPITIKAGGFFPISLPTF 305


                  ....*...
gi 24644502   380 LQIVKLIY 387
Cdd:pfam02949 306 ISILKFAY 313
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH