heparan sulfate 6-O-sulfotransferase, isoform A [Drosophila melanogaster]
sulfotransferase family protein( domain architecture ID 10507897)
sulfotransferase family protein may catalyze the transfer of sulfate from a donor such as 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to an acceptor substrate; such as heparan-sulfate 6-O-sulfotransferases, which catalyze the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate
List of domain hits
Name | Accession | Description | Interval | E-value | |||||
Sulfotransfer_2 | pfam03567 | Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. ... |
144-411 | 2.24e-30 | |||||
Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate. : Pssm-ID: 427369 Cd Length: 238 Bit Score: 117.63 E-value: 2.24e-30
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Name | Accession | Description | Interval | E-value | |||||
Sulfotransfer_2 | pfam03567 | Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. ... |
144-411 | 2.24e-30 | |||||
Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate. Pssm-ID: 427369 Cd Length: 238 Bit Score: 117.63 E-value: 2.24e-30
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Name | Accession | Description | Interval | E-value | |||||
Sulfotransfer_2 | pfam03567 | Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. ... |
144-411 | 2.24e-30 | |||||
Sulfotransferase family; This family includes a variety of sulfotransferase enzymes. Chondroitin 6-sulfotransferase catalyzes the transfer of sulfate to position 6 of the N-acetylgalactosamine residue of chondroitin. This family also includes Heparan sulfate 2-O-sulfotransferase (HS2ST) and Heparan sulfate 6-sulfotransferase (HS6ST). Heparan sulfate (HS) is a co-receptor for a number of growth factors, morphogens, and adhesion proteins. HS biosynthetic modifications may determine the strength and outcome of HS-ligand interactions. Mice that lack HS2ST undergo developmental failure only after midgestation,the most dramatic effect being the complete failure of kidney development. Heparan sulphate 6- O -sulfotransferase (HS6ST) catalyzes the transfer of sulphate from adenosine 3'-phosphate, 5'-phosphosulphate to the 6th position of the N -sulphoglucosamine residue in heparan sulphate. Pssm-ID: 427369 Cd Length: 238 Bit Score: 117.63 E-value: 2.24e-30
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Blast search parameters | ||||
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