|
Name |
Accession |
Description |
Interval |
E-value |
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
5-396 |
0e+00 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 722.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 5 RVYVVGVGMTKFEKPGRQADvcYPDFAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAIYEVGMTGIPVYNVNNN 84
Cdd:PRK08256 2 KVFVAGVGMTPFEKPGASWD--YPDMAAEAGRAALADAGIDYDAVQQAYVGYVYGDSTSGQRALYEVGMTGIPIVNVNNN 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 85 CSTGSSALYLAKQIVESGNADCVLALGFEKMERGSLSSKYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKEHMKK 164
Cdd:PRK08256 80 CSTGSTALFLARQAVRSGAADCALALGFEQMQPGALGSVWDDRPSPLERFDKALAELQGFDPAPPALRMFGGAGREHMEK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 165 YGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEGvLTKLQCCPTSDGSGAAILASEAFVRRHGLEkQAV 244
Cdd:PRK08256 160 YGTTAETFAKIGVKARRHAANNPYAQFRDEYTLEDVLASPMIWGP-LTRLQCCPPTCGAAAAIVCSEEFARKHGLD-RAV 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 245 EIVGMEMASDPASTFADKSLMKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGNAGEFID 324
Cdd:PRK08256 238 EIVAQAMTTDTPSTFDGRSMIDLVGYDMTRAAAQQVYEQAGIGPEDIDVVELHDCFSANELLTYEALGLCPEGEAEKFID 317
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24585051 325 AGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGLGGAVVVALYR 396
Cdd:PRK08256 318 DGDNTYGGRWVVNPSGGLLSKGHPLGATGLAQCAELTWQLRGTAGARQVEGARLALQHNLGLGGACVVTLYQ 389
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
9-395 |
1.62e-159 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 459.04 E-value: 1.62e-159
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 9 VGVGMTKFEKPGrqaDVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVYGD---STCGQRAIYEVGMTGIPVYNVNNNC 85
Cdd:cd00829 1 VGVGMTPFGRRS---DRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGrfqSFPGALIAEYLGLLGKPATRVEAAG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 86 STGSSALYLAKQIVESGNADCVLALGFEKMERGSLSSKYFDRANPMERHItemgelAEIGAGPMAAQIFGNAGKEHMKKY 165
Cdd:cd00829 78 ASGSAAVRAAAAAIASGLADVVLVVGAEKMSDVPTGDEAGGRASDLEWEG------PEPPGGLTPPALYALAARRYMHRY 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 166 GTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEgVLTKLQCCPTSDGSGAAILASEAFVRRHGleKQAVE 245
Cdd:cd00829 152 GTTREDLAKVAVKNHRNAARNPYAQFRKPITVEDVLNSRMIAD-PLRLLDCCPVSDGAAAVVLASEERARELT--DRPVW 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 246 IVGMEMASDPASTFADKSlmkIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGNAGEFIDA 325
Cdd:cd00829 229 ILGVGAASDTPSLSERDD---FLSLDAARLAARRAYKMAGITPDDIDVAELYDCFTIAELLALEDLGFCEKGEGGKLVRE 305
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 326 GDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGLGGAVVVALY 395
Cdd:cd00829 306 GDTAIGGDLPVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAGARQVPGARVGLAHNIGGTGSAAVVTI 375
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
9-395 |
2.21e-151 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 439.24 E-value: 2.21e-151
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 9 VGVGMTKFEKPGRQADVCYPDFAREAITKALQDAGIKY----EEVQQAVAGYVYGD---STCGQRAIYE-VGMTGIPVYN 80
Cdd:cd00826 1 AGAAMTAFGKFGGENGADANDLAHEAGAKAIAAALEPAgvaaGAVEEACLGQVLGAgegQNCAQQAAMHaGGLQEAPAIG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 81 VNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMErgslsskYFDRANPMERHITEMGELAEIGAGPMAAQIFGNAGKE 160
Cdd:cd00826 81 MNNLCGSGLRALALAMQLIAGGDANCILAGGFEKME-------TSAENNAKEKHIDVLINKYGMRACPDAFALAGQAGAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 161 HMKKYGTKPEHFGKIAWKN---HKHSVNNPYSQFRDEYTLEQIMKSPQVV--EGVLTKLQCCPTSDGSGAAILASEAFVR 235
Cdd:cd00826 154 AAEKDGRFKDEFAKFGVKGrkgDIHSDADEYIQFGDEASLDEIAKLRPAFdkEDFLTAGNACGLNDGAAAAILMSEAEAQ 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 236 RHGLEKQAVEIVGMEMASDPASTFADKSLMKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCG 315
Cdd:cd00826 234 KHGLQSKAREIQALEMITDMASTFEDKKVIKMVGGDGPIEAARKALEKAGLGIGDLDLIEAHDAFAANACATNEALGLCP 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 316 EGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGLGGAVVVALY 395
Cdd:cd00826 314 EGQGGALVDRGDNTYGGKSIINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRQGAGAGLALLCIGGGGGAAMCIES 393
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
4-397 |
1.73e-96 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 298.35 E-value: 1.73e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 4 TRVYVVGVGMTKFekpGRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAIYEV-----GMTGIPV 78
Cdd:PRK06064 2 RDVAIIGVGQTKF---GELWDVSLRDLAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLFVSQEHIAALiadyaGLAPIPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 YNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMergslsskyfdranpmerhiTEMGELAEIGAGPMAAQIF--GN 156
Cdd:PRK06064 79 TRVEAACASGGAALRQAYLAVASGEADVVLAAGVEKM--------------------TDVPTPDATEAIARAGDYEweEF 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 157 AG-----------KEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEGvLTKLQCCPTSDGSGA 225
Cdd:PRK06064 139 FGatfpglyaliaRRYMHKYGTTEEDLALVAVKNHYNGSKNPYAQFQKEITVEQVLNSPPVADP-LKLLDCSPITDGAAA 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 226 AILASEAFVRRhgLEKQAVEIVGMEMASDpasTFADKSLMKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANEL 305
Cdd:PRK06064 218 VILASEEKAKE--YTDTPVWIKASGQASD---TIALHDRKDFTTLDAAVVAAEKAYKMAGIEPKDIDVAEVHDCFTIAEI 292
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 306 ITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAE--KRQVPNAQLALQHN 383
Cdd:PRK06064 293 LAYEDLGFAKKGEGGKLAREGQTYIGGDIPVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAEkgRQQVIGAGYGLTHN 372
|
410
....*....|....*
gi 24585051 384 L-GLGGAVVVALYRL 397
Cdd:PRK06064 373 VgGTGHTAVVHILSR 387
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
5-396 |
4.21e-76 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 245.53 E-value: 4.21e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 5 RVYVVGVGMTKFekpGRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGyvygdsTCGQRAiYEV----------GMT 74
Cdd:PRK12578 2 RVAVIGVGNSKF---GRRDDVSVQELAWESIKEALNDAGVSQTDIELVVVG------STAYRG-IELypapivaeysGLT 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 75 GIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMER---------GSLSSKYFdranpMERHITemgelaeig 145
Cdd:PRK12578 72 GKVPLRVEAMCATGLAASLTAYTAVASGLVDMAIAVGVDKMTEvdtstslaiGGRGGNYQ-----WEYHFY--------- 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 146 aGPMAAQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSpQVVEGVLTKLQCCPTSDGSGA 225
Cdd:PRK12578 138 -GTTFPTYYALYATRHMAVYGTTEEQMALVSVKAHKYGAMNPKAHFQKPVTVEEVLKS-RAISWPIKLLDSCPISDGSAT 215
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 226 AILASEAFVRRHGLEkQAVEIVGMEMASDPASTFADKSLMkiaGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANEL 305
Cdd:PRK12578 216 AIFASEEKVKELKID-SPVWITGIGYANDYAYVARRGEWV---GFKATQLAARQAYNMAKVTPNDIEVATVHDAFTIAEI 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 306 ITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVP-NAQLALQHNL 384
Cdd:PRK12578 292 MGYEDLGFTEKGKGGKFIEEGQSEKGGKVGVNLFGGLKAKGHPLGATGLSMIYEITKQLRDEAGKLQQPlKKYIGLVHNV 371
|
410
....*....|....
gi 24585051 385 GLGG--AVVVALYR 396
Cdd:PRK12578 372 GGTGhfAYVMILRR 385
|
|
| PRK06059 |
PRK06059 |
lipid-transfer protein; Provisional |
6-393 |
1.32e-68 |
|
lipid-transfer protein; Provisional
Pssm-ID: 180373 [Multi-domain] Cd Length: 399 Bit Score: 226.18 E-value: 1.32e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 6 VYVVGVGMTKFEKPGRQadvcYPDFAREAITKALQDAGIKYEEVQQAVA---------GYVYGdSTCGQRaiyeVGMTGI 76
Cdd:PRK06059 6 VYILGAGMHPWGKWGRD----FVEYGVVAARAALADAGLDWRDVQLVVGadtirngypGFVAG-ATFAQA----LGWNGA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 77 PVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGSLSSKYFDRANP---MERHItemgelaeIGAGPMAaqI 153
Cdd:PRK06059 77 PVSSSYAACASGSQALQSARAQILAGLCDVALVVGADTTPKGFFAPVGGERPDDpdwLRFHL--------IGATNPV--Y 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 154 FGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPqVVEGVLTKLQCCPTSDGSGAAILASEAF 233
Cdd:PRK06059 147 FALLARRRMDLYGATVEDFAQVKVKNARHGLLNPNARYRKEVTVEDVLASP-VVSDPLRLLDICATSDGAAALIVASKSF 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 234 VRRHGLE-KQAVEIVGMEMASdpaSTFADKSL-MKIAGTDMTRL--ATQRLF---------AKSGYKPQDVQVVELHDCF 300
Cdd:PRK06059 226 ARRHLGSvAGVPSVRAISTVT---PRYPQHLPeLPDIATDSTAAvpAPERVFkdqildaayAEAGIGPEDLSLAEVYDLS 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 301 SANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLAL 380
Cdd:PRK06059 303 TALELDWYEHLGLCPKGEAEALLRSGATTLGGRIPVNPSGGLACFGEAIPAQAIAQVCELTWQLRGQAGGRQVEGARVGI 382
|
410
....*....|....*.
gi 24585051 381 QHNLGL---GGAVVVA 393
Cdd:PRK06059 383 TANQGLfghGSSVIVA 398
|
|
| PRK06157 |
PRK06157 |
acetyl-CoA acetyltransferase; Validated |
3-403 |
2.47e-65 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 180433 [Multi-domain] Cd Length: 398 Bit Score: 217.59 E-value: 2.47e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 3 KTRVYVVGVGMTKFekpGRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAI---YEVGMTGIPVY 79
Cdd:PRK06157 6 KDKVAILGMGCTKF---GERWDAGAEDLMVEAFLEALADAGIEPKDIDAAWFGTHYDEIGSGKSGTplsRALRLPNIPVT 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 80 NVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKME---RGSLSSKYFDRANPMERhitemgelAEIGAGPMAAQIFGN 156
Cdd:PRK06157 83 RVENFCATGSEAFRGAVYAVASGAYDIALALGVEKLKdtgYGGLPVANPGTLADMTM--------PNVTAPGNFAQLASA 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 157 AGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPqVVEGVLTKLQCCPTSDGSGAAILASEAFVRR 236
Cdd:PRK06157 155 YAAKYGVSREDLKRAMAHVSVKSHANGARNPKAHLRKAVTEEQVLKAP-MIAGPLGLFDCCGVSDGAAAAIVTTPEIARA 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 237 HGlEKQAVEIVGMEMASDPASTFADKslmkiaGTDMTRLATQRLFAKSGYK------PQ-DVQVVELHDCFSANELITYE 309
Cdd:PRK06157 234 LG-KKDPVYVKALQLAVSNGWELQYN------GWDGSYFPTTRIAARKAYReagitdPReELSMAEVHDCFSITELVTME 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 310 ALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGlgga 389
Cdd:PRK06157 307 DLGLSERGQAWRDVLDGFFDADGGLPCQIDGGLKCFGHPIGASGLRMLYEMYLQLLGRAGERQLKNPRLALTHNLG---- 382
|
410
....*....|....
gi 24585051 390 vvvalyrlGFPAAN 403
Cdd:PRK06157 383 --------GAPGQN 388
|
|
| PRK07516 |
PRK07516 |
thiolase domain-containing protein; |
4-390 |
2.48e-62 |
|
thiolase domain-containing protein;
Pssm-ID: 181013 [Multi-domain] Cd Length: 389 Bit Score: 209.42 E-value: 2.48e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 4 TRVYVVGVGMTKFekpGRQADVCYPDFAREAITKALQDAGIKYEEVQQAV-----AGYVYGDSTCGQRAIYEVGMTGIPV 78
Cdd:PRK07516 2 MTASIVGWAHTPF---GKLDAETLESLIVRVAREALAHAGIAAGDVDGIFlghfnAGFSPQDFPASLVLQADPALRFKPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 YNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGS--------LSSKYFdranpmerhitemGELAEIGAGpmA 150
Cdd:PRK07516 79 TRVENACATGSAAVYAALDAIEAGRARIVLVVGAEKMTATPtaevgdilLGASYL-------------KEEGDTPGG--F 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 151 AQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLE---QIMKSPQVVEGVLTKLQCCPTSDGSGAAI 227
Cdd:PRK07516 144 AGVFGRIAQAYFQRYGDQSDALAMIAAKNHANGVANPYAQMRKDLGFEfcrTVSEKNPLVAGPLRRTDCSLVSDGAAALV 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 228 LASEAFVRRHgleKQAVEIVGMEMASD--PASTfadKSLMKIAGTdmtRLATQRLFAKSGYKPQDVQVVELHDCFSANEL 305
Cdd:PRK07516 224 LADAETARAL---QRAVRFRARAHVNDflPLSR---RDPLAFEGP---RRAWQRALAQAGVTLDDLSFVETHDCFTIAEL 294
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 306 ITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLG 385
Cdd:PRK07516 295 IEYEAMGLAPPGQGARAIREGWTAKDGKLPVNPSGGLKAKGHPIGATGVSMHVLAAMQLTGEAGGMQIPGAKLAGVFNMG 374
|
....*
gi 24585051 386 lGGAV 390
Cdd:PRK07516 375 -GAAV 378
|
|
| PRK06365 |
PRK06365 |
thiolase domain-containing protein; |
2-394 |
1.99e-54 |
|
thiolase domain-containing protein;
Pssm-ID: 235785 [Multi-domain] Cd Length: 430 Bit Score: 189.74 E-value: 1.99e-54
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 2 SKTR-VYVVGVGMTKFEKPGRQADvcYPDFAREAITKALQDAGIKYEEVQQAVAGYV---YGDSTCGQRAIYE-VGMTGI 76
Cdd:PRK06365 13 KKSRdVYMVAAGVTKFDKASPYMD--FRERVKKAFDYAMNDAGLTLADIDGSVASYFsdhFQRQLLAGIMVQDyLGLVPK 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 77 PVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMER----------GSLSSKYFDraNPMERHITemgelaeiGA 146
Cdd:PRK06365 91 PSKRIEGGGATGGLAFQAGYEEIASGRMDCVAVYGFETMSHvntwkgnefiALASDTNFD--YPLGGFYT--------GY 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 147 GPMAAQifgnagkEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPqVVEGVLTKLQCCPTSDGSGAA 226
Cdd:PRK06365 161 YAMMAV-------RHMYEFGTTVEQLAKVSVKNHGNAIHNPFAQSPMKITVEDVRKSP-MVSYPLTRLDVCAMSDGAACA 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 227 ILASEAfvRRHGLEKQAVEIVGMEMASD---------------PASTFADKSLMKIAGTDMTRLAtqRLFAKSGYK---- 287
Cdd:PRK06365 233 ILASED--KAFEITDKPVLIKAIGTGSDtlrladrpfgevpllPNESPDDYKDLRYPGVHSFRAG--RMAAKEAYEmagi 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 288 ---PQDVQVVELHDCFSANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQL 364
Cdd:PRK06365 309 tdpLNDLDLIELHDAYTSSEIQTYEDLGLCKYGEGGQFIESGKPELPGKLPVNPSGGLLAAGHAVGATGIMQAVFMFWQL 388
|
410 420 430
....*....|....*....|....*....|....*..
gi 24585051 365 RGLAEKR------QVPNAQLALQH-NLGLGGAVVVAL 394
Cdd:PRK06365 389 QGRIKKHfhddylQVKNAKRGLIHsHAGTGTYVTVTI 425
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
6-394 |
4.63e-48 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 171.79 E-value: 4.63e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 6 VYVVGVGMTKF----EKPGRQadvcYPDFAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQR------AIYEVGMTG 75
Cdd:PRK06289 5 VWVLGGYQSDFarnwTKEGRD----FADLTREVVDGTLAAAGVDADDIEVVHVGNFFGELFAGQGhlgampATVHPALWG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 76 IPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMergslsskyfdRANPMERHITEMGELAEIG-----AGPMA 150
Cdd:PRK06289 81 VPASRHEAACASGSVATLAAMADLRAGRYDVALVVGVELM-----------KTVPGDVAAEHLGAAAWTGhegqdARFPW 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 151 AQIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFR-----DEYTLEQIMKSPqVVEGVLTKLQCCPTSDGSGA 225
Cdd:PRK06289 150 PSMFARVADEYDRRYGLDEEHLRAIAEINFANARRNPNAQTRgwafpDEATNDDDATNP-VVEGRLRRQDCSQVTDGGAG 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 226 AILASEAFVRRHGLEKQAVEIVGMEMASDPAsTFADKsLMKIAGTDM----TRLATQRLFAKSGYKPQDVQVVELHDCFS 301
Cdd:PRK06289 229 VVLASDAYLRDYADARPIPRIKGWGHRTAPL-GLEQK-LDRSAGDPYvlphVRQAVLDAYRRAGVGLDDLDGFEVHDCFT 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 302 ANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQ 381
Cdd:PRK06289 307 PSEYLAIDHIGLTGPGESWKAIENGEIAIGGRLPINPSGGLIGGGHPVGASGVRMLLDAAKQVTGTAGDYQVEGAKTFGT 386
|
410
....*....|...
gi 24585051 382 HNLGLGGAVVVAL 394
Cdd:PRK06289 387 LNIGGSTTTTVSF 399
|
|
| PRK08313 |
PRK08313 |
thiolase domain-containing protein; |
2-398 |
2.38e-46 |
|
thiolase domain-containing protein;
Pssm-ID: 181378 [Multi-domain] Cd Length: 386 Bit Score: 166.83 E-value: 2.38e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 2 SKTRVYVVGVGMTKFEkpGRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVYG--DSTCGQRAIYE--VGMTGIP 77
Cdd:PRK08313 1 MKRLAAVLGTGQTKYV--AKRQDVSMAGLVREAIDRALADAGLTWDDIDAVVVGKAPDffEGVMMPELFLAdaLGATGKP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 78 VYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGslsskyfdraNPMERHITEMGELAEIGAGpmAAQIFGNA 157
Cdd:PRK08313 79 LIRVHTAGSVGGSTAVVAASLVQSGVYRRVLAVAWEKQSES----------NAMWALSIPVPFTKPVGAG--AGGYFAPH 146
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 158 GKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRD-EYTLEQIMKSPQVVEGVlTKLQCCPTSDGSGAAILASEAFVRR 236
Cdd:PRK08313 147 VRAYIRRSGAPEHIGAMVAVKDRLNGAKNPYAHLHQpDITLEKVMASQMLWDPI-RFDETCPSSDGACAVVIGDEEAADA 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 237 HGlEKQAVEIVGMEMASDPastfadkslMKIAGTDMT-----RLATQRLFAKSGYK-PQD-VQVVELHDCFSANELITYE 309
Cdd:PRK08313 226 AA-GRPVAWIHGTAMRTEP---------LAFAGRDQVnpqagRDAAAALWKAAGITdPRDeIDVAEIYVPFSWFEPMWLE 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 310 ALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISkGHPLGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHNLGlGGA 389
Cdd:PRK08313 296 NLGFAPEGEGWKLTEAGETAIGGRLPVNPSGGVLS-SNPIGASGMIRFAEAALQVMGKAGEHQVDGARKALGHAYG-GGS 373
|
....*....
gi 24585051 390 VVVALYRLG 398
Cdd:PRK08313 374 QFFSMWVVG 382
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
28-392 |
1.33e-44 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 157.99 E-value: 1.33e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 28 PDFAREAITKALQDAGIKYEEVQQAVAGYVYGD---STCGQRAIYEVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNA 104
Cdd:cd00327 8 SELGFEAAEQAIADAGLSKGPIVGVIVGTTGGSgefSGAAGQLAYHLGISGGPAYSVNQACATGLTALALAVQQVQNGKA 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 105 DCVLALGFEKmergslsskyfdranpmerhitemgelaeigagpmaaqifgnagkehmkkygtkpehfgkiawknhkhsv 184
Cdd:cd00327 88 DIVLAGGSEE---------------------------------------------------------------------- 97
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 185 nnpysqfrdeytleqimkspqvvegvltklqcCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMemasdpASTFADKSL 264
Cdd:cd00327 98 --------------------------------FVFGDGAAAAVVESEEHALRRGAHPQA-EIVST------AATFDGASM 138
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 265 MKIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGNAGefidagdntyggkfvVNPSGGLIS 344
Cdd:cd00327 139 VPAVSGEGLARAARKALEGAGLTPSDIDYVEAHGTGTPIGDAVELALGLDPDGVRS---------------PAVSATLIM 203
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|
gi 24585051 345 KGHPLGATGLAQCAELCWQLR--GLAEKRQVPNAQLALQHNLGLGGAVVV 392
Cdd:cd00327 204 TGHPLGAAGLAILDELLLMLEheFIPPTPREPRTVLLLGFGLGGTNAAVV 253
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
2-388 |
1.63e-35 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 138.10 E-value: 1.63e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 2 SKTRVYVVGVGMTKFEKPGRQ--ADVCYPDFAR-----------EAITKALQDAGIKYEE--VQQAVAGYVYGD-----S 61
Cdd:PTZ00455 10 AAKRVFVVGGHITPFVGKGSPlfIDKKHPDFGKkenktleellaTAIQGTLENTGLDGKAalVDKVVVGNFLGElfssqG 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 62 TCGQRAIYEVGMTGI-------PVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGS--LSSKYFDRANPME 132
Cdd:PTZ00455 90 HLGPAAVGSLGQSGAsnallykPAMRVEGACASGGLAVQSAWEALLAGTSDIALVVGVEVQTTVSarVGGDYLARAADYR 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 133 RHitemGELAEIGAGPMAAQIFgnagkEHMKKYGT-KPEHFGKIAWKNHKHSVNNPYSQ-FRDEYTLEQIM----KSP-- 204
Cdd:PTZ00455 170 RQ----RKLDDFTFPCLFAKRM-----KYIQEHGHfTMEDTARVAAKAYANGNKNPLAHmHTRKLSLEFCTgasdKNPkf 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 205 ---QVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGL---EKQAVEIVGMEMAS-----DPASTfadkslmkiagTDM- 272
Cdd:PTZ00455 241 lgnETYKPFLRMTDCSQVSDGGAGLVLASEEGLQKMGLspnDSRLVEIKSLACASgnlyeDPPDA-----------TRMf 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 273 -TRLATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGA 351
Cdd:PTZ00455 310 tSRAAAQKALSMAGVKPSDLQVAEVHDCFTIAELLMYEALGIAEYGHAKDLIRNGATALEGRIPVNTGGGLLSFGHPVGA 389
|
410 420 430
....*....|....*....|....*....|....*..
gi 24585051 352 TGLAQCAELCWQLRGLAEKRQVPNAqLALQHNLGLGG 388
Cdd:PTZ00455 390 TGVKQIMEVYRQMKGQCGEYQMKNI-PALGATLNMGG 425
|
|
| PRK08142 |
PRK08142 |
thiolase domain-containing protein; |
1-389 |
4.77e-35 |
|
thiolase domain-containing protein;
Pssm-ID: 236164 [Multi-domain] Cd Length: 388 Bit Score: 135.60 E-value: 4.77e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 1 MS-KTRVYVVGVgmtkFEKPGRQA-DVCYPDFAREAITKALQDAGIKYEEVQqavaGYVYGDSTCGQRAIYEVGMTGIPV 78
Cdd:PRK08142 1 MSiKGKAYIVGA----YEHPTRKApDKSVAQLHAEVAKGALADAGLSLADVD----GYFCAGDAPGLGPASMVDYLGLKL 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 YNVNNNCSTGSSalYL-----AKQIVESGNadCVLAL-GFEKMERGSLSSKYFDRAnpmerHITEMGELA-EIGAGPMAA 151
Cdd:PRK08142 73 RHVDSTETGGSS--YLahvghAAQAIAAGK--CSVALiTLAGRPRSEGSSGTEPRN-----WGADAPDAPfEAPYGPTTH 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 152 QIFGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEGvLTKLQCCPTSDGSGAAILASE 231
Cdd:PRK08142 144 NLYAMCAMRHMHEYGTTSEQLAWIKVAASHHAQHNPHAMLRDVVTVEDVLNSPMIADP-LHRLDCCVVTDGGGALVVVRP 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 232 AFVRRhgLEKQAVEIVGmemasdpaSTFADKSLMKiAGTDMT----RLATQRLFAKSGYKPQDVQVVELHDCFSANELIT 307
Cdd:PRK08142 223 EIARS--LKRPLVKVLG--------AGEAIKGQMG-GKVDLTysgaAWSGPAAFAEAGVTPADIKYASIYDSFTITVLMQ 291
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 308 YEALGLCGEGNAGEFIDAGDNTYG-GKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAE-KRQVPNAQLALQHnlG 385
Cdd:PRK08142 292 LEDLGFCKKGEGGKFVADGNLISGvGKLPFNTDGGGLCNNHPANRGGMTKVIEAVRQLRGEAHpAVQVPNCDLALAH--G 369
|
....
gi 24585051 386 LGGA 389
Cdd:PRK08142 370 TGGL 373
|
|
| PRK06158 |
PRK06158 |
thiolase; Provisional |
5-388 |
1.41e-33 |
|
thiolase; Provisional
Pssm-ID: 180434 [Multi-domain] Cd Length: 384 Bit Score: 131.31 E-value: 1.41e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 5 RVYVVGVGMTKF-EKPGRQAdvcyPDFAREAITKALQDAGIKYEEVQQAVAGYVYgDSTCGQRAIYEVGMTgiPVYnVNN 83
Cdd:PRK06158 9 RTAIVGAATAGLgEAPGLSA----MELLAQAAHRALADAGLTMADVDGLFTASPD-DALWGLSVAEYLGIR--PRF-VDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 84 NCSTGSS---ALYLAKQIVESGNADCVL-------ALGFEKMERGSLSSKYFDRANPMerhitemgelAEIGAGPMAAQi 153
Cdd:PRK06158 81 TMIGGSSflaHLLPAALALEAGLCDVALicygsnqRSAGGKLRSMLDPQPYEAPYKPV----------NPVSAYALAAA- 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 154 fgnagkEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSpQVVEGVLTKLQCCPTSDGSGAAILASEAf 233
Cdd:PRK06158 150 ------RHMHQYGTTREQLAEVAVAARQWAQLNPEAFMRDPLTIDDVLAA-RMVSDPLSVRDCCLVTDGAGAVVMVRAD- 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 234 vRRHGLEKQAVEIVGMEMASdpasTFADKSLMKiagtDMTRLAT----QRLFAKSGYKPQDVQVVELHDCFSANELITYE 309
Cdd:PRK06158 222 -RARDLPRPPVYVLGAAAAT----WHRQISSMP----DLTVTAAaesgPRAFAMAGLTPADIDVVELYDAFTINTILFLE 292
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24585051 310 ALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPlGATGLAQCAELCWQLRGLAEKRQVPNAQLALQHnlGLGG 388
Cdd:PRK06158 293 DLGFCAKGEGGAFVEGGRIAPGGRLPVNTNGGGLSCVHP-GMYGLFLLIEAVRQLRGEAGERQVAGAEVALAH--GNGG 368
|
|
| PRK06065 |
PRK06065 |
thiolase domain-containing protein; |
3-374 |
2.94e-32 |
|
thiolase domain-containing protein;
Pssm-ID: 180379 [Multi-domain] Cd Length: 392 Bit Score: 128.02 E-value: 2.94e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 3 KTRVYVVGVGMTKFEkpgRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY----GDSTCGQRAIYEVGMTGIPV 78
Cdd:PRK06065 8 NKRVAVIGAGLTLFR---RRLLETPQELAWEAASKALDEAGLELKDIDCVVIGSAPdafdGVHMKGEYLSHGSGGIRKPV 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 YNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGslsskyfdRANPME--RHITEmgELAEIGAGPMAAQIFGN 156
Cdd:PRK06065 85 SRVYVGGATGVMTAIAGWYHVASGLCQKVLAVAEEKMSPA--------RPHPQAvfRYIWD--PILEKPLNPNLIWIFAM 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 157 AGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEGVlTKLQCCPTSDGSGAAILASEAFVRR 236
Cdd:PRK06065 155 EMHRYMATYGIKKEEIALVSVKNKRNALNNPYAQLGSKITVEDVLKSEVLVWPV-QLLDVSPVSDGAAAIVLASEDLARR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 237 HGLEKQAVEIVGM----------EMASDPASTFADKSLMKIAGTDMTRlatqrlfaksgykpQDVQVVELHDCFSANELI 306
Cdd:PRK06065 234 YTDTPVWVEGVGWtldntewpnrDLAYPRYVEFAARMAYKMAGIERPR--------------KEIDVAEPYDPFDYKELH 299
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 24585051 307 TYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQVP 374
Cdd:PRK06065 300 HLEGLQLAKRGEAPKLLKEGVFDIDGDIPSSPSGGLLGVGNPIAAAGLMKVISIYWQLKGTAGKMQVK 367
|
|
| PRK06066 |
PRK06066 |
thiolase domain-containing protein; |
162-406 |
3.29e-30 |
|
thiolase domain-containing protein;
Pssm-ID: 180380 [Multi-domain] Cd Length: 385 Bit Score: 121.78 E-value: 3.29e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 162 MKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDEYTLEQIMKSPQVVEGvLTKLQCCPTSDGSGAAILASEAFVRRhgLEK 241
Cdd:PRK06066 154 MSRKGITREDLALVVEKNKKAGLSNPRASYASNISLEDVLSSEYVVYP-LTELDIAPFVDGAIVVVLASEEVAKK--LTD 230
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 242 QAVEIVGMEMASDPAStfadkslmkIAGTDMTRLATQRLFAKSGYK------PQ-DVQVVELHDCFSANELITYEALGLC 314
Cdd:PRK06066 231 DPVWIKGIGWSTESSN---------LETAELGKANYMRIAADMAYKmagiesPRkEVDAAEVDDRYSYKELQHIEALRLS 301
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 315 GEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLAQCAELCWQLRGLAEKRQvPNAQLAlqhnlglggavVVAL 394
Cdd:PRK06066 302 EEPEKDSLLREGNFDPQGELPVNPSGGHLAKGVPLEASGLSLLLDAVEYLRGEAGARQ-GKAERA-----------VVAS 369
|
250
....*....|..
gi 24585051 395 YRlGFPAANSVV 406
Cdd:PRK06066 370 WR-GIPTLTGSV 380
|
|
| PRK07855 |
PRK07855 |
lipid-transfer protein; Provisional |
8-380 |
1.11e-27 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181147 [Multi-domain] Cd Length: 386 Bit Score: 114.69 E-value: 1.11e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 8 VVGVGMTKFEK-PGRQAdvcyPDFAREAITKALQDAGIKYEEVQqAVAGYVYgDSTcgqrAIYEVG-MTGIPV------- 78
Cdd:PRK07855 8 IVGIGATEFSKnSGRSE----LRLACEAVLAALDDAGLAPSDVD-GLVTFTM-DTN----PEIAVArALGIGElkffsri 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 -YNVNNNCST-GSSALYLAkqiveSGNADCVLAlgFEKMERGS---LSSKYFDRANPMERHITEMGELAEIGAGPMAAQI 153
Cdd:PRK07855 78 hYGGGAACATvQQAAMAVA-----TGVADVVVC--YRAFNERSgmrFGQGQTGLAENPTSTGVDYGWSYPHGLLTPAAWV 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 154 fGNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYSQFRDE-YTLEQIMKSPQVVEGvLTKLQCCPTSDGSGAAILASEA 232
Cdd:PRK07855 151 -AMLARRYMHEYGATSEDFGRVAVADRKHAATNPKAWFYGRpITLEDHQNSRWIAEP-LRLLDCCQESDGAVALVVTSAE 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 233 fvRRHGLEKQAVEIVGMEMASDPastfaDKSLM------KIAGTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSANELI 306
Cdd:PRK07855 229 --RARDLKQRPAVIKAAAQGSGA-----DQYMMtsyyrdDITGLPEMGLVARQLWAQSGLGPADIDTAILYDHFTPFVLM 301
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24585051 307 TYEALGLCGEGNAGEFIDAGDNTYGGKFVVNPSGGLISKGHPLGATGLaqcAELCWQLRGLAEKrQVPNAQLAL 380
Cdd:PRK07855 302 QLEELGFCGRGEAKDFIADGALELGGRLPINTHGGQLGEAYIHGMNGI---AEAVRQLRGTSVN-QVPGVENVL 371
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
28-392 |
1.53e-26 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 111.42 E-value: 1.53e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 28 PDFAREAITKALQDAGIKYEEVQQAVAGYVYGdSTCGQ---RAIyeVGMTGIPV----YNVNNNCSTGSSALYLAKQIVE 100
Cdd:cd00751 23 DDLGAAVIKALLERAGLDPEEVDDVIMGNVLQ-AGEGQnpaRQA--ALLAGLPEsvpaTTVNRVCGSGLQAVALAAQSIA 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 101 SGNADCVLALGFEKMERGSLSSK----YFDRANPMERHITEMGELAEIGAGPMaaqifGNAGKEHMKKYG---------- 166
Cdd:cd00751 100 AGEADVVVAGGVESMSRAPYLLPkarrGGRLGLNTLDGMLDDGLTDPFTGLSM-----GITAENVAEKYGisreeqdefa 174
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 167 ----------TKPEHFG------KIAWKNHKHSVNnpysqfRDEY-----TLEQIMKSPQVVE--GVLTKLQCCPTSDGS 223
Cdd:cd00751 175 lrshqraaaaQEAGRFKdeivpvEVPGRKGPVVVD------RDEGprpdtTLEKLAKLKPAFKkdGTVTAGNASGINDGA 248
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 224 GAAILASEAFVRRHGLEKQAVeIVGMEMASDpastfaDKSLMKIAGTdmtrLATQRLFAKSGYKPQDVQVVELHDCFSAN 303
Cdd:cd00751 249 AAVLLMSEEKAKELGLKPLAR-IVGYAVAGV------DPAIMGIGPV----PAIPKALKRAGLTLDDIDLIEINEAFAAQ 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 304 ELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGATGLAQCAELcwqLRGLAEKrqvpNAQLALQ-- 381
Cdd:cd00751 318 ALACLKELGLDPE------------------KVNVNGGAIALGHPLGASGARIVVTL---LHELKRR----GGRYGLAtm 372
|
410
....*....|..
gi 24585051 382 -HNLGLGGAVVV 392
Cdd:cd00751 373 cIGGGQGAAMVI 384
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
14-392 |
4.54e-24 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 104.23 E-value: 4.54e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 14 TKFEKPGRQ-ADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY---GDSTCGQRAIYEVGM-TGIPVYNVNNNCSTG 88
Cdd:TIGR01930 7 TPIGKFGGSlKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLqagEQQNIARQAALLAGLpESVPAYTVNRQCASG 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 89 SSALYLAKQIVESGNADCVLALGFEKM----------ERGSLSSKYFDRANPMERHITE------MGELAEigagpMAAQ 152
Cdd:TIGR01930 87 LQAVILAAQLIRAGEADVVVAGGVESMsrvpygvprsLRWGVKPGNAELEDARLKDLTDantglpMGVTAE-----NLAK 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 153 IFG--------NAGKEHMK-KYGTKPEHFGK----IAWKNHKHSVNNPYSQF-RDEYTLEQIMKSPQV--VEGVLTKLQC 216
Cdd:TIGR01930 162 KYGisreeqdeYALRSHQRaAKAWEEGLFKDeivpVTVKGRKGPVTVSSDEGiRPNTTLEKLAKLKPAfdPDGTVTAGNS 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 217 CPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMAS-DPAstfadksLMKIAGTdmtrLATQRLFAKSGYKPQDVQVVE 295
Cdd:TIGR01930 242 SPLNDGAAALLLMSEEKAKELGLTPLA-RIVSFAVAGvDPE-------IMGLGPV----PAIPKALKKAGLSISDIDLFE 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 296 LHDCFSANELITYEALGLcgegnagefidaGDNTyggkfvVNPSGGLISKGHPLGATGLAQCAELCWQLR------GLAe 369
Cdd:TIGR01930 310 INEAFAAQVLACIKELGL------------DLEK------VNVNGGAIALGHPLGASGARIVTTLLHELKrrggryGLA- 370
|
410 420
....*....|....*....|...
gi 24585051 370 krqvpnaqlALQHNLGLGGAVVV 392
Cdd:TIGR01930 371 ---------TMCIGGGQGAAVIL 384
|
|
| SCP2 |
pfam02036 |
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the ... |
428-531 |
2.00e-23 |
|
SCP-2 sterol transfer family; This domain is involved in binding sterols. It is found in the SCP2 protein as well as the C terminus of the enzyme estradiol 17 beta-dehydrogenase EC:1.1.1.62. The UNC-24 protein contains an SPFH domain pfam01145.
Pssm-ID: 460423 [Multi-domain] Cd Length: 100 Bit Score: 94.63 E-value: 2.00e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 428 LKLLEQAMqEDKDNLIEKVRA-IYGFKVNNGPngqtGFWVIDAKQGKGKIIFNGTQKCDVTFIISDDDVFELLTGKLPPQ 506
Cdd:pfam02036 1 LNQLLARD-PAARELLKKLNGkVIRFDLTDLG----LSLTLDLKDGGGRVLAGDEGKADVTLSASDSDLLALATGKLNPQ 75
|
90 100
....*....|....*....|....*
gi 24585051 507 KAFFQGKIKIQGNMGFAMKLMDLQR 531
Cdd:pfam02036 76 KAFMQGKLKIEGDMELAQKLEGLLK 100
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
28-353 |
4.92e-21 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 95.13 E-value: 4.92e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 28 PDFAREAITKALQDAGIKYEEVQQAVAGYVY--GDSTCGQRAIyeVGMTGIPV----YNVNNNCSTGSSALYLAKQIVES 101
Cdd:COG0183 27 DDLGAAVIKALLERAGLDPEAVDDVILGCVLqaGQGQNPARQA--ALLAGLPEsvpaVTVNRVCGSGLQAVALAAQAIAA 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 102 GNADCVLALGFEKMERG-----------SLSSKYFDR-ANP--MERHITE-MGELAEigagpMAAQIFG----------- 155
Cdd:COG0183 105 GDADVVIAGGVESMSRApmllpkarwgyRMNAKLVDPmINPglTDPYTGLsMGETAE-----NVAERYGisreeqdafal 179
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 156 ----NAGKehmkkygtkpehfgkiAWKNHKHS-----VNNPYSQF-----RDEY-----TLEQI--MKSPQVVEGVLTKL 214
Cdd:COG0183 180 rshqRAAA----------------AIAAGRFDdeivpVEVPDRKGevvvdRDEGprpdtTLEKLakLKPAFKKDGTVTAG 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 215 QCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASdpastfADKSLMKIAGTdmtrLATQRLFAKSGYKPQDVQVV 294
Cdd:COG0183 244 NASGINDGAAALLLMSEEAAKELGLKPLA-RIVAYAVAG------VDPEIMGIGPV----PATRKALARAGLTLDDIDLI 312
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 24585051 295 ELHDCFSANELITYEALGlcgegnagefIDAGdntyggkfVVNPSGGLISKGHPLGATG 353
Cdd:COG0183 313 EINEAFAAQVLAVLRELG----------LDPD--------KVNVNGGAIALGHPLGASG 353
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
6-232 |
8.69e-19 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 86.20 E-value: 8.69e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 6 VYVVGVGMTKFEK-PGRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVyGDSTCGQ---RAIyeVGMTGIPV--- 78
Cdd:pfam00108 1 VVIVSAARTPFGSfGGSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNV-LQAGEGQnpaRQA--ALKAGIPDsap 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 79 -YNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGSlsskYFDRANPMErHITEMGELAEIGAGPMAAQIFGNa 157
Cdd:pfam00108 78 aVTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMSHAP----YALPTDARS-GLKHGDEKKHDLLIPDGLTDAFN- 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 158 gKEHM--------KKYGTKPEHFGKIAWKNHKHSVNNPYSQ-FRDE--------------YTLEQIMKSPQVVE------ 208
Cdd:pfam00108 152 -GYHMgltaenvaKKYGISREEQDAFAVKSHQKAAAAPKAGkFKDEivpvtvkgrkgkptVDKDEGIRPPTTAEplaklk 230
|
250 260 270
....*....|....*....|....*....|
gi 24585051 209 ------GVLTKLQCCPTSDGSGAAILASEA 232
Cdd:pfam00108 231 pafdkeGTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
6-353 |
2.31e-18 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 87.08 E-value: 2.31e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 6 VYVVGVGMTKFEKPGR---QADVCY----PDFAREAITKALQDAGIKYEEVQQAVAG--------YVYGdstcGQRAIYE 70
Cdd:PRK06445 4 VYLVDFARTAFSRFRPkdpQKDVFNnirpEELAAMLINRLIEKTGIKPEEIDDIITGcalqvgenWLYG----GRHPIFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 71 VGM-TGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGSLSSkyfdraNP-MERHITEM--GELAE--- 143
Cdd:PRK06445 80 ARLpYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMTRTPMGD------NPhIEPNPKLLtdPKYIEydl 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 144 -IG--AGPMAAQIFGNAG--KEHMKKYGTKpEHfgKIAWK-------------------NHKHSVNNPYSqFRDEYTLEQ 199
Cdd:PRK06445 154 tTGyvMGLTAEKLAEEAGikREEMDRWSLR-SH--QLAAKaiqegyfkdeilpieveveGKKKVVDVDQS-VRPDTSLEK 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 200 IMKSPQVV--EGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASDPASTFADKSLMkiagtdmtrlAT 277
Cdd:PRK06445 230 LAKLPPAFkpDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMA-KIRSFGFAGVPPAIMGKGPVP----------AS 298
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24585051 278 QRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGATG 353
Cdd:PRK06445 299 KKALEKAGLSVKDIDLWEINEAFAVVVLYAIKELGLDPE------------------TVNIKGGAIAIGHPLGATG 356
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
6-353 |
2.87e-16 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 80.82 E-value: 2.87e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 6 VYVVGVGMTKFEKPGRQ-ADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY----GDSTCGQrAIYEVGMT-GIPVY 79
Cdd:PRK06366 4 VYIVSAKRTAIGKFGRSfSKIKAPQLGGAAIKAVIDDAKLDPALVQEVIMGNVIqagvGQNPAGQ-AAYHAGLPfGVTKY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 80 NVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGS--LSSKYfdRANPMER-HITEMGELAEIGAGPMAAQIF-- 154
Cdd:PRK06366 83 TVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPflLPSDL--RWGPKHLlHKNYKIDDAMLVDGLIDAFYFeh 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 155 -GNAGKEHMKKYGTKPEHFGKIAWKNHKHSVNNPYS-QFRDEY---------------TLEQIMKSPQVVE--GVLTKLQ 215
Cdd:PRK06366 161 mGVSAERTARKYGITREMADEYSVQSYERAIRATESgEFRNEIvpfndldrdegirktTMEDLAKLPPAFDknGILTAGN 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 216 CCPTSDGSGAAILASEAFVRRHGLeKQAVEIVGMEMASDPASTFADKSLMkiagtdmtrlATQRLFAKSGYKPQDVQVVE 295
Cdd:PRK06366 241 SAQLSDGGSALVMASEKAINEYGL-KPIARITGYESASLDPLDFVEAPIP----------ATRKLLEKQNKSIDYYDLVE 309
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*...
gi 24585051 296 LHDCFSANELITYEALGLcgegnagefidagDNTyggKFVVNpsGGLISKGHPLGATG 353
Cdd:PRK06366 310 HNEAFSIASIIVRDQLKI-------------DNE---RFNVN--GGAVAIGHPIGNSG 349
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
192-353 |
1.18e-15 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 78.84 E-value: 1.18e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 192 RDEYTLEQIMKSPQVV--EGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASDPAStfadksLMKIAG 269
Cdd:PRK09050 227 RPETTLEALAKLKPVFrpDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTPRA-RILGMATAGVEPR------IMGIGP 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 270 TDmtrlATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLcgegnagefidAGDNTYggkfvVNPSGGLISKGHPL 349
Cdd:PRK09050 300 AP----ATRKLLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGL-----------ADDDAR-----VNPNGGAIALGHPL 359
|
....
gi 24585051 350 GATG 353
Cdd:PRK09050 360 GMSG 363
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
76-353 |
3.82e-14 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 73.97 E-value: 3.82e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 76 IPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGSLSSkyfdrANPMERhitEMGELAEIGAGPMAAQIFG 155
Cdd:PRK07801 80 VPGVTVDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMSQIPISS-----AMTAGE---QLGFTSPFAESKGWLHRYG 151
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 156 NA------GKEHM-KKYGTKPEHFGKIAWKNHKHSVNN-----------PYSQFRD-----EYTLEQIMKSPQVVEG-VL 211
Cdd:PRK07801 152 DQevsqfrGAELIaEKWGISREEMERFALESHRRAFAAiragrfdneivPVGGVTVdegprETSLEKMAGLKPLVEGgRL 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 212 TKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASDpastfaDKSLMKIAGTDMTRLATQrlfaKSGYKPQDV 291
Cdd:PRK07801 232 TAAVASQISDGASAVLLASERAVKRHGLTPRA-RIHHLSVRGD------DPVFMLTAPIPATRYALE----KTGLSIDDI 300
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24585051 292 QVVELHDCFSANELITYEALGLCGEGnagefidagdntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK07801 301 DVVEINEAFAPVVLAWLKETGADPAK------------------VNPNGGAIALGHPLGATG 344
|
|
| SCP2 |
COG3255 |
Putative sterol carrier protein, contains SCP2 domain [Lipid transport and metabolism]; |
433-529 |
4.41e-14 |
|
Putative sterol carrier protein, contains SCP2 domain [Lipid transport and metabolism];
Pssm-ID: 442486 [Multi-domain] Cd Length: 104 Bit Score: 68.39 E-value: 4.41e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 433 QAMQE--DKDNLIEKVRAIYGFKVNNGPNGQtgfWVIDAKQGKGKIIFNGTQKCDVTFIISDDDVFELLTGKLPPQKAFF 510
Cdd:COG3255 5 EALCEklNAADAAAGWDGVVQFVITGEGGGA---YYLVIDDGKCTVSEGDDDDADVTLTASYEDWKKLLTGELDPMTAFM 81
|
90
....*....|....*....
gi 24585051 511 QGKIKIQGNMGFAMKLMDL 529
Cdd:COG3255 82 TGKLKVEGDMGLAMKLMSL 100
|
|
| PRK07937 |
PRK07937 |
lipid-transfer protein; Provisional |
91-384 |
8.22e-13 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181173 [Multi-domain] Cd Length: 352 Bit Score: 69.72 E-value: 8.22e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 91 ALYLAKQIVESGNADCVLALGFEKMERGSLsskyfDRANPMErhiTEMGELAEIGAGPMA-----AQIFGNAGKehmkky 165
Cdd:PRK07937 89 ALYEAWVKLLTGEVDTALVYGFGKSSAGTL-----RRVLALQ---LDPYTVAPLWPDSVSmaglqARAGLDAGK------ 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 166 gTKPEHFGKIAWKNHKHSVNNPYSQfrDEYTLEQIMKSPQVVEGvLTKLQCCPTSDGSGAAILASEAFVRRHgLEKQAVe 245
Cdd:PRK07937 155 -WTEEQMAEVAARSRADARRNPSAE--PSISVDELLARPYFADP-LRRHDIAPITDGAAAVVLAAGDRAREL-RERPAW- 228
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 246 IVGMEMASDPAStfadkslmkIAGTDMTRLATQRLFAK--SGYKPQDVQVVELHDCFSANELITYEALGLcgegnagefi 323
Cdd:PRK07937 229 ITGIEHRIESPS---------LGARDLTRSPSTALAAEaaTGGDAGGVDVAELHAPFTHQELILREALGL---------- 289
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24585051 324 daGDNTyggkfVVNPSGGLISkGHPLGATGLAQCAELCWQL------RGLAEKRQVPnaqlALQHNL 384
Cdd:PRK07937 290 --GDKT-----KVNPSGGALA-ANPMFAAGLERIGEAARHIwdgsarRALAHATSGP----ALQQNL 344
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
20-353 |
7.06e-12 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 67.29 E-value: 7.06e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 20 GRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVYG----DSTCGQRAIYEVGMT-GIPVYNVNNNCSTGSSALYL 94
Cdd:PRK09051 20 GSLKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPteprDMYLSRVAAINAGVPqETPAFNVNRLCGSGLQAIVS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 95 AKQIVESGNADCVLALGFEKMERGSlsskYFDranPMERHITEMGELAEIGAgpMAAQIFGNAGKEHM--------KKYG 166
Cdd:PRK09051 100 AAQAILLGDADVAIGGGAESMSRAP----YLL---PAARWGARMGDAKLVDM--MVGALHDPFGTIHMgvtaenvaAKYG 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 167 TKPEHFGKIAWKNHK---HSVNNPY--SQ--------------------FRDEYTLEQIMKSPQVV---EGVLTKLQCCP 218
Cdd:PRK09051 171 ISREAQDALALESHRraaAAIAAGYfkDQivpveiktrkgevvfdtdehVRADTTLEDLAKLKPVFkkeNGTVTAGNASG 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 219 TSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMAS-DPAstfadksLMKIAGTDmtrlATQRLFAKSGYKPQDVQVVELH 297
Cdd:PRK09051 251 INDGAAAVVLAEADAAEARGLKPLA-RLVGYAHAGvDPE-------YMGIGPVP----ATQKALERAGLTVADLDVIEAN 318
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*.
gi 24585051 298 DCFSANELITYEALGLcgegnagefiDAGDntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK09051 319 EAFAAQACAVTRELGL----------DPAK--------VNPNGSGISLGHPVGATG 356
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
23-353 |
1.86e-11 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 65.94 E-value: 1.86e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 23 ADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY----GDSTCGQRAIYevgmTGIPV----YNVNNNCSTGSSALYL 94
Cdd:PRK05790 22 KDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLqagaGQNPARQAALK----AGLPVevpaLTINKVCGSGLKAVAL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 95 AKQIVESGNADCVLALGFEKMER------GSLS-SKYFDraNPMERHITE-----------MGELAEIGAgpmaaqifgn 156
Cdd:PRK05790 98 AAQAIRAGDADIVVAGGQESMSQaphvlpGSRWgQKMGD--VELVDTMIHdgltdafngyhMGITAENLA---------- 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 157 agkehmKKYG-TKPE--HFG-------KIAWKNHKhsvnnpysqFRDE---YTLEQIMKSPQVV---EGV--------LT 212
Cdd:PRK05790 166 ------EQYGiTREEqdEFAlasqqkaEAAIKAGR---------FKDEivpVTIKQRKGDPVVVdtdEHPrpdttaesLA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 213 KLQ-------------CCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGmemasdPASTFADKSLMKIAGTDmtrlATQR 279
Cdd:PRK05790 231 KLRpafdkdgtvtagnASGINDGAAAVVVMSEAKAKELGLTPLA-RIVS------YAVAGVDPAIMGIGPVP----AIRK 299
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 24585051 280 LFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGATG 353
Cdd:PRK05790 300 ALEKAGWSLADLDLIEINEAFAAQALAVEKELGLDPE------------------KVNVNGGAIALGHPIGASG 355
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
34-353 |
2.98e-11 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 65.11 E-value: 2.98e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 34 AITKALQDAGIKYEEVQQAVAGYV----YGDSTCGQRAIyevgMTGIP----VYNVNNNCSTGSSALYLAKQIVESGNAD 105
Cdd:PLN02644 32 AIQAALERAGVDPALVQEVFFGNVlsanLGQAPARQAAL----GAGLPpstiCTTVNKVCASGMKAVMLAAQSIQLGIND 107
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 106 CVLALGFEKMergSLSSKYFDRANPMER--HIT-----------------EMGELAEIGAGPM----------------- 149
Cdd:PLN02644 108 VVVAGGMESM---SNAPKYLPEARKGSRlgHDTvvdgmlkdglwdvyndfGMGVCAELCADQYsisreeqdayaiqsyer 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 150 --AAQIFGNAGKEHM-----KKYGTKPehfgKIAWKNHKHSVNNPYSqfrdeytLEQIMKSPQVVEGVLTKLQCCPTSDG 222
Cdd:PLN02644 185 aiAAQEAGAFAWEIVpvevpGGRGRPS----VIVDKDEGLGKFDPAK-------LRKLRPSFKEDGGSVTAGNASSISDG 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 223 SGAAILASEAFVRRHGLEKQAVeIVGMEMASDPASTFadkslmkiagTDMTRLATQRLFAKSGYKPQDVQVVELHDCFSA 302
Cdd:PLN02644 254 AAALVLVSGEKALELGLQVIAK-IRGYADAAQAPELF----------TTAPALAIPKALKHAGLEASQVDYYEINEAFSV 322
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|.
gi 24585051 303 NELITYEALGLCGEGnagefidagdntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PLN02644 323 VALANQKLLGLDPEK------------------VNVHGGAVSLGHPIGCSG 355
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
74-365 |
3.42e-11 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 65.02 E-value: 3.42e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 74 TGIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKME-------RGSLSSKYFDR------------------- 127
Cdd:PRK09052 84 NSVGGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSmvpmmgnKPSMSPAIFARdenvgiaygmgltaekvae 163
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 128 ----------ANPMERHiteMGELAEIGAGPMAAQIFGNAGKEHMKKYGTkpehfGKIAwkNHKHSVNN---PysqfRDE 194
Cdd:PRK09052 164 qwkvsredqdAFALESH---QKAIAAQQAGEFKDEITPYEITERFPDLAT-----GEVD--VKTRTVDLdegP----RAD 229
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 195 YTLEQIMKSPQV--VEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASDPAStfadksLMKIAGTDm 272
Cdd:PRK09052 230 TSLEGLAKLKPVfaNKGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLA-RFVSFAVAGVPPE------IMGIGPIE- 301
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 273 trlATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGAT 352
Cdd:PRK09052 302 ---AIPAALKQAGLKQDDLDWIELNEAFAAQSLAVIRDLGLDPS------------------KVNPLGGAIALGHPLGAT 360
|
330
....*....|...
gi 24585051 353 GLAQCAELCWQLR 365
Cdd:PRK09052 361 GAIRTATVVHGLR 373
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
221-353 |
4.91e-11 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 64.52 E-value: 4.91e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 221 DGSGAAILASEAFVRRHGLEKQAvEIVGMemasdpASTFADKSLMKIAGTDmtrlATQRLFAKSGYKPQDVQVVELHDCF 300
Cdd:PRK08242 261 DGAAAVLIGSEEAGKALGLKPRA-RIVAT------ATIGSDPTIMLTGPVP----ATRKALAKAGLTVDDIDLFELNEAF 329
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 24585051 301 SANELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGATG 353
Cdd:PRK08242 330 ASVVLRFMQALDIPHD------------------KVNVNGGAIAMGHPLGATG 364
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
73-353 |
2.04e-09 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 59.59 E-value: 2.04e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 73 MTGIP----VYNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMERGSLS---------SKYFDRANPMerhiteMG 139
Cdd:PRK08947 75 LAGIPhsvpAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMGHVPMNhgvdfhpglSKNVAKAAGM------MG 148
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 140 ELAEigagpMAAQIFGnAGKEHMKKYGTKPEHFGKIA-----WKN-----HKHSVNNPYSQF------RDEYTLEQIMKS 203
Cdd:PRK08947 149 LTAE-----MLGKMHG-ISREQQDAFAARSHQRAWAAtqegrFKNeiiptEGHDADGVLKLFdydeviRPETTVEALAAL 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 204 PQV---VEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAVeIVGMEMASdpastfADKSLMKIAGTDmtrlATQRL 280
Cdd:PRK08947 223 RPAfdpVNGTVTAGTSSALSDGASAMLVMSESRAKELGLKPRAR-IRSMAVAG------CDPSIMGYGPVP----ATQKA 291
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 24585051 281 FAKSGYKPQDVQVVELHDCFSANELITYEALGLcgegnagefIDAGDNTyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK08947 292 LKRAGLSISDIDVFELNEAFAAQSLPCLKDLGL---------LDKMDEK------VNLNGGAIALGHPLGCSG 349
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
20-353 |
2.67e-09 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 59.13 E-value: 2.67e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 20 GRQADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY----GDSTCGQRAIYEVGMTGIPVYNVNNNCSTGSSALYLA 95
Cdd:PRK05656 19 GSLANIPAVELGAAVIRRLLEQTGLDPAQVDEVILGQVLtagaGQNPARQAAIKAGLPHSVPAMTLNKVCGSGLKALHLA 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 96 KQIVESGNADCVLALGFEKMergSLSSKYFdranPMERHITEMGElAEIGAGPMAAQIFGNAGKEHM--------KKYGT 167
Cdd:PRK05656 99 AQAIRCGDAEVIIAGGQENM---SLAPYVL----PGARTGLRMGH-AQLVDSMITDGLWDAFNDYHMgitaenlvEKYGI 170
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 168 KPEHFGKIAWKNHKHSVNNPYS-QFRDEYTLEQI---------------------------MKSPQVVEGVLTKLQCCPT 219
Cdd:PRK05656 171 SREAQDAFAAASQQKAVAAIEAgRFDDEITPILIpqrkgeplafatdeqpragttaeslakLKPAFKKDGSVTAGNASSL 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 220 SDGSGAAILASEAFVRRHGLEKQAvEIVGMemasdpASTFADKSLMKIAGTDmtrlATQRLFAKSGYKPQDVQVVELHDC 299
Cdd:PRK05656 251 NDGAAAVLLMSAAKAKALGLPVLA-KIAAY------ANAGVDPAIMGIGPVS----ATRRCLDKAGWSLAELDLIEANEA 319
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....
gi 24585051 300 FSANELITYEALGLcgegnagefiDAGDntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK05656 320 FAAQSLAVGKELGW----------DAAK--------VNVNGGAIALGHPIGASG 355
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
23-353 |
5.01e-08 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 55.38 E-value: 5.01e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 23 ADVCYPDFAREAITKALQDAGIKYEEVQQAVAGYVY--GDSTC-GQRAIYEVGM-TGIPVYNVNNNCSTGSSALYLAKQI 98
Cdd:PRK06205 22 KDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYpnGEAPAiGRVAALDAGLpVTVPGMQLDRRCGSGLQAVITAAMQ 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 99 VESGNADCVLALGFEKM--------------ERGSLssKYFDR-------ANPmERH--ITEMGELAEigagpmaaqifg 155
Cdd:PRK06205 102 VQTGAADVVIAGGAESMsnvefyttdmrwgvRGGGV--QLHDRlargretAGG-RRFpvPGGMIETAE------------ 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 156 NAGKEhmkkYGTKPEHFGKIAWKNHKHSV---------------------NNPYSQFRDEY-----TLEQIMK-----SP 204
Cdd:PRK06205 167 NLRRE----YGISREEQDALAVRSHQRAVaaqeagrfddeivpvtvpqrkGDPTVVDRDEHpradtTLESLAKlrpimGK 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 205 QVVEGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMASDPASTfadkslMKIAGTDmtrlATQRLFAKS 284
Cdd:PRK06205 243 QDPEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLA-RLVSWAVAGVEPSR------MGIGPVP----ATEKALARA 311
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24585051 285 GYKPQDVQVVELHDCFSAnelityEALGLCGEGNagefIDAGDNTyggKFVVNPSGglISKGHPLGATG 353
Cdd:PRK06205 312 GLTLDDIDLIELNEAFAA------QVLAVLKEWG----FGADDEE---RLNVNGSG--ISLGHPVGATG 365
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
208-353 |
2.84e-07 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 52.70 E-value: 2.84e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 208 EGVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAvEIVGMemasdpASTFADKSLMKIAGTDmtrlATQRLFAKSGYK 287
Cdd:PRK07851 251 DGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLA-RIVST------GVSGLSPEIMGLGPVE----ASKQALARAGMS 319
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 24585051 288 PQDVQVVELHDCFSANELITYEALGlcgegnagefIDAGDntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK07851 320 IDDIDLVEINEAFAAQVLPSARELG----------IDEDK--------LNVSGGAIALGHPFGMTG 367
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
192-392 |
4.65e-07 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 52.09 E-value: 4.65e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 192 RDEYTLEQIMKSPQVVE-GVLTKLQCCPTSDGSGAAILASEAFVRRHGLEKQAVEIVGMEMASDPastfadkSLMKIAGT 270
Cdd:PRK08131 227 RPSSTVEALTKLKPLFEgGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEP-------RIMGIGPV 299
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 271 DMTRLATQRlfakSGYKPQDVQVVELHDCFSANELITYEALGLcgegnagefidAGDNTYggkfvVNPSGGLISKGHPLG 350
Cdd:PRK08131 300 EAIKKALAR----AGLTLDDMDIIEINEAFASQVLGCLKGLGV-----------DFDDPR-----VNPNGGAIAVGHPLG 359
|
170 180 190 200
....*....|....*....|....*....|....*....|....
gi 24585051 351 ATG--LAQCAelcwqLRGLaEKRQVPNAQLALQHNLGLGGAVVV 392
Cdd:PRK08131 360 ASGarLALTA-----AREL-QRRGKRYAVVSLCIGVGQGLAMVI 397
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
221-353 |
6.01e-07 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 51.70 E-value: 6.01e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 221 DGSGAAILASEAFVRRHGLEKQAvEIVGM-EMASDPastfadkSLMKIAGTDmtrlATQRLFAKSGYKPQDVQVVELHDC 299
Cdd:PRK06025 276 DGAAALLLASKAYAEKHGLKPRA-RIVAMaNMGDDP-------TLMLNAPVP----AAKKVLAKAGLTKDDIDLWEINEA 343
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*.
gi 24585051 300 FS--ANELItyEALGLCGEGnagefidagdntyggkfvVNPSGGLISKGHPLGATG 353
Cdd:PRK06025 344 FAvvAEKFI--RDLDLDRDK------------------VNVNGGAIALGHPIGATG 379
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
275-353 |
1.23e-06 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 47.64 E-value: 1.23e-06
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 24585051 275 LATQRLFAKSGYKPQDVQVVELHDCFSANELITYEALGLCGEgnagefidagdntyggkfVVNPSGGLISKGHPLGATG 353
Cdd:pfam02803 26 YAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPE------------------KVNVNGGAIALGHPLGASG 86
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
218-370 |
1.87e-06 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 50.28 E-value: 1.87e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 218 PTSDGSGAAILASEAFVRRHGLEKQAvEIVGMEMAsdpASTFADKS---LMkiAGTdmtrLATQRLFAKSGYKPQDVQVV 294
Cdd:PRK09268 263 PLTDGASVVLLASEEWAAEHGLPVLA-YLVDAETA---AVDFVHGKeglLM--APA----YAVPRLLARNGLTLQDFDFY 332
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 295 ELHDCFSANELITYEA----------LGLcgEGNAGEfIDAGDntyggkfvVNPSGGLISKGHPLGATG---LAQCAELc 361
Cdd:PRK09268 333 EIHEAFASQVLATLKAwedeeycrerLGL--DAPLGS-IDRSK--------LNVNGSSLAAGHPFAATGgriVATLAKL- 400
|
....*....
gi 24585051 362 wqlrgLAEK 370
Cdd:PRK09268 401 -----LAEK 404
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
29-117 |
2.78e-06 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 49.34 E-value: 2.78e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 29 DFAREAITKALQDAGIKYEEVQQAVAGYVYGD----ST-CG-QRAIyevGMTGIPVYNVNNNCSTGSSALYLAKQIVESG 102
Cdd:COG0332 53 DLAVEAARKALEAAGIDPEDIDLIIVATVTPDylfpSTaCLvQHKL---GAKNAAAFDINAACSGFVYALSVAAALIRSG 129
|
90
....*....|....*
gi 24585051 103 NADCVLALGFEKMER 117
Cdd:COG0332 130 QAKNVLVVGAETLSR 144
|
|
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
27-357 |
2.35e-05 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 47.07 E-value: 2.35e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 27 YPDFAREAITKALQDA-GIKYEEVQQAVAGYVYGDSTcgQRAIyEVGMTG--------IPVYNVNNNCSTGSSALYLAKQ 97
Cdd:PLN02287 70 YPDDLLAPVLKAVVEKtGLNPSEVGDIVVGTVLAPGS--QRAN-ECRMAAfyagfpetVPVRTVNRQCSSGLQAVADVAA 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 98 IVESGNADCVLALGFEKMERGSLSSKYfdRANPMerhiTEMGELAEIGAGPMaaqifGNAGKEHMKKYGTKPEHFGKIAW 177
Cdd:PLN02287 147 AIKAGFYDIGIGAGVESMTTNPMAWEG--GVNPR----VESFSQAQDCLLPM-----GITSENVAERFGVTREEQDQAAV 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 178 KNHKHSVNNPYS-QFRDEY------------------------------TLEQIMKSPQVVE--GVLTKLQCCPTSDGSG 224
Cdd:PLN02287 216 ESHRKAAAATASgKFKDEIvpvhtkivdpktgeekpivisvddgirpntTLADLAKLKPVFKknGTTTAGNSSQVSDGAG 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 225 AAILASEAFVRRHGLEkqaveIVGMemasdpASTFA----DKSLMKIAGTdmtrLATQRLFAKSGYKPQDVQVVELHDCF 300
Cdd:PLN02287 296 AVLLMKRSVAMQKGLP-----ILGV------FRSFAavgvDPAVMGIGPA----VAIPAAVKAAGLELDDIDLFEINEAF 360
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 24585051 301 SANELITYEALGLCGEGnagefidagdntyggkfvVNPSGGLISKGHPLGATGlAQC 357
Cdd:PLN02287 361 ASQFVYCCKKLGLDPEK------------------VNVNGGAIALGHPLGATG-ARC 398
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
29-117 |
1.20e-04 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 44.45 E-value: 1.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 29 DFAREAITKALQDAGIKYEEV----------QQ---AVAGYVygdstcgQRAIyevGMTGIPVYNVNNNCSTGSSALYLA 95
Cdd:cd00830 52 DLAVEAAKKALEDAGIDADDIdliivatstpDYlfpATACLV-------QARL---GAKNAAAFDINAACSGFLYGLSTA 121
|
90 100
....*....|....*....|..
gi 24585051 96 KQIVESGNADCVLALGFEKMER 117
Cdd:cd00830 122 AGLIRSGGAKNVLVVGAETLSR 143
|
|
| init_cond_enzymes |
cd00827 |
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
28-111 |
1.26e-04 |
|
"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are characterized by the utlization of CoA substrate primers, as well as the nature of their active site residues.
Pssm-ID: 238423 [Multi-domain] Cd Length: 324 Bit Score: 44.35 E-value: 1.26e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 28 PDFAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAIY---EVGMTGIPVYNVNNNCSTGSSALYLAKQIVESGNA 104
Cdd:cd00827 49 PTMAVEAARRALERAGIDPDDIGLLIVATESPIDKGKSAATYlaeLLGLTNAEAFDLKQACYGGTAALQLAANLVESGPW 128
|
....*..
gi 24585051 105 DCVLALG 111
Cdd:cd00827 129 RYALVVA 135
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
30-126 |
2.27e-04 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 43.68 E-value: 2.27e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 30 FAREAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAIYE---------------------------------VGMTGi 76
Cdd:cd00834 74 FALAAAEEALADAGLDPEELDPERIGVVIGSGIGGLATIEEayrallekgprrvspffvpmalpnmaagqvairLGLRG- 152
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 24585051 77 PVYNVNNNCSTGSSALYLAKQIVESGNADCVLA------------LGFEKMerGSLSSKYFD 126
Cdd:cd00834 153 PNYTVSTACASGAHAIGDAARLIRLGRADVVIAggaealitpltlAGFAAL--RALSTRNDD 212
|
|
| PRK08257 |
PRK08257 |
acetyl-CoA acetyltransferase; Validated |
186-313 |
1.31e-03 |
|
acetyl-CoA acetyltransferase; Validated
Pssm-ID: 236204 [Multi-domain] Cd Length: 498 Bit Score: 41.44 E-value: 1.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24585051 186 NPYSQFRDEYTLEQI-MKSPQ--VVEGVLTKLQCC-PTSDGSGAAILASEAFVRRHGL-EKQAVEIVGMEMASDPAS--- 257
Cdd:PRK08257 205 NPHAWIPRERSAEEIvTPTPDnrMIAWPYTKLMNAnDMVDQGAAVLLTSVAKARRLGVpEDRWVYLHGGADAHDPYDile 284
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 24585051 258 --TFADKSLMKIAGtdmtrlatQRLFAKSGYKPQDVQVVELHDCF-SANELITyEALGL 313
Cdd:PRK08257 285 rpDLHRSPAIRAAG--------RRALALAGLGIDDIDAFDLYSCFpSAVQVAA-RELGL 334
|
|
| ACP_syn_III |
pfam08545 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl- ... |
79-129 |
1.36e-03 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.180, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430064 [Multi-domain] Cd Length: 80 Bit Score: 37.88 E-value: 1.36e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 24585051 79 YNVNNNCSTGSSALYLAKQIVESGNADCVLALGFEKMergslsSKYFDRAN 129
Cdd:pfam08545 1 FDINAACSGFVYALSTAAALIRSGRAKNVLVIGAETL------SKILDWTD 45
|
|
| PRK12404 |
PRK12404 |
stage V sporulation protein AD; Provisional |
33-109 |
5.40e-03 |
|
stage V sporulation protein AD; Provisional
Pssm-ID: 183504 Cd Length: 334 Bit Score: 39.21 E-value: 5.40e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 24585051 33 EAITKALQDAGIKYEEVQQAVAGYVYGDSTCGQRAIYEVGmtgIPVYNVNNNCSTGSSALYLAKQIVESGNADCVLA 109
Cdd:PRK12404 60 EACSRAIEKAKLRKEDIQFFLAGDLMNQITPTSFAARTLG---IPYLGLFGACSTSMEGLALAALIVNSGGAKYVLT 133
|
|
| |
