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L-fucokinase/GDP-L-fucose pyrophosphorylase [Arabidopsis thaliana]
Protein Classification
fkp and Fucokinase domain-containing protein ( domain architecture ID 13490766 )
fkp and Fucokinase domain-containing protein
List of domain hits
Name
Accession
Description
Interval
E-value
Fucokinase
pfam07959 L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated ...
131-529
2.86e-153
L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated by L-fucokinase to form L-fucose-L-phosphate, which is then further converted to GDP-L-fucose in the reaction catalyzed by GDP-L-fucose pyrophosphorylase.
Pssm-ID: 462323
Cd Length: 405
Bit Score: 460.96
E-value: 2.86e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 131 AGG D S K R V P W A NPM GK V F LP LP Y laa D DP D GPV PL L F D HI LAI A S CARQ af QDQG G LFIMTG DV LPC FDA FKMTLPEDAA 210
Cdd:pfam07959 1 AGG Y S Q R L P S A SAL GK I F TA LP L --- E DP G GPV YQ L L D LK LAI Y S DFPS -- RMKP G VLVCST DV ILL FDA NEISFDKPGV 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 211 SIVTV P IT L D I AS NHGV I V TSKSE S LAESYTVS L VN D L L Q KP TV E D L VKKD A I L H DG RTL LD T GI ISAR G RAWSD L V AL G 290
Cdd:pfam07959 76 TALAH P SS L A I GT NHGV F V LDPQG S SEKDLEIG L CR D F L H KP SE E E L QASG A V L K DG FVY LD S GI VFFD G KTAEK L L AL Y 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 291 C S CQ P MIL E LIGSKKEMS LY E D LVA A WV P SRHDWLRT ------------ RP LG E L L VNS L GRQKMYSY C TYDLQ F L HFGT 358
Cdd:pfam07959 156 V S PG P LDC E TYLGPLQID LY G D FLQ A LG P GATLEYFL ntanvgkeeasl RP AR E E L WKL L RGTPLNVI C LPNSK F Y HFGT 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 359 SS E V L D HL S GD A S GI V GR rhlc SIPA T TV S D IA ------ A SSVILS S EIA PGVS I G ED S L I YDSTVS G A V Q IGS QS I VV G 432
Cdd:pfam07959 236 TA E Y L E HL T GD C S LR V EL ---- GLTS T AF S V IA narqlk A GASVIN S VLE PGVS V G PG S V I EYCHLG G P V S IGS GC I LS G 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 433 IHIP S ED lgtpes F R FM LPD RHC L WEV PL VGHK G -- R V I V YC G L HDN P K N S IH - KDG TF C GKPLE KV L FDL GI EES DLW S 509
Cdd:pfam07959 312 LDLS S SL ------ A R LE LPD DTF L HTL PL KLGG G kl Y V T V VF G I HDN L K S S VS d GNL TF L GKPLE DF L SLT GI QPE DLW F 385
410 420
....*....|....*....|
gi 18378810 510 S YVAQDRC LWNA K LFP ILTY 529
Cdd:pfam07959 386 S GEPREKS LWNA R LFP VCHD 405
fkp super family
cl36248 bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
32-1042
6.23e-105
bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
PRK13412 :Pssm-ID: 237379 [Multi-domain]
Cd Length: 974
Bit Score: 351.44
E-value: 6.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 32 PTWDAI V LTAA S P EQ AELYD W qlrrakrmgriasstvt LAVP DP D G KRI GSG AA T LNAIY A LA R HYEK l G F D LG pemeva 111
Cdd:PRK13412 31 SLPPNL V DSFH S L EQ VDRTE W ----------------- FCTS DP V G QKL GSG GG T TWLLE A CF R NGSP - G G D FT ------ 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 112 ngac K W vrf ISAKHVLM LHAGG D S K R V P WAN P M GK VFL P L P YLAA ddpd GPVPL L FDHI L AIASCARQAFQDQG ---- GL 187
Cdd:PRK13412 87 ---- E W --- LGKEKRIL LHAGG Q S R R L P GYA P S GK ILT P V P VFRW ---- ERGQR L SQNL L SLQLPLYERIMSKA pegl HT 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 188 F I MT GDV LPCFDAFKMTL PE da A SI V TVPITL D -- I A S NHGV I V T S KS eslaesy TVSLVNDL LQKP TV E D L vkk DAILH 265
Cdd:PRK13412 156 L I AS GDV YIRSEQPLQDI PE -- A DV V CYGLWV D ps L A T NHGV F V S S RK ------- SPERLDFM LQKP SL E E L --- GGLSK 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 266 DGRT L L D T GI ISARG RA WSD L VALG cscqpm IL E LI G SK K EMS LY E D LVA A ---- WVPSRHD wlrtrp L GE L L V NS L GRQ 341
Cdd:PRK13412 224 THLF L M D I GI WLLSD RA VEL L MKRS ------ GK E DG G KL K YYD LY S D FGL A lgth PRIGDDE ------ L NA L S V AI L PLP 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 342 KM ysyctydl Q F L H F GTS S E VLD ------ H L SG D ASG I VG R R hlcsipattv SDIAASSVILSSEIAPGVSIGEDS L - I Y 414
Cdd:PRK13412 292 GG -------- E F Y H Y GTS R E LIS stlavq N L VT D QRR I MH R K ---------- VKPHPAMFVQNAVLSGKLTAENAT L w I E 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 415 D S T V SGAVQIG S Q SI VV G I hipsedlgt PE - S FRFM LP DRH C LWE VP l VG HK G R V IVYC GL H D NP K NSIHKD - G T FC G K P 492
Cdd:PRK13412 354 N S H V GEGWKLA S R SI IT G V --------- PE n S WNLD LP EGV C IDV VP - VG DR G F V ARPY GL D D VF K GALADG k T T WF G R P 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 493 LEKVLFDL G IEES DL wssy VAQDRC L WN A K LFP IL T YS E M L - KLAS W LMGLDDS rn K E KIKL W RS S QRV S LE E L hgsinf 571
Cdd:PRK13412 424 FLEWMEAR G LSWP DL ---- KGRTDD L QA A H LFP VV T SV E E L g AVLR W MLSEPSL -- E E GKEI W LR S EKL S AD E I ------ 491
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 572 pemcngss NHQ A D LA GGI A KAC ---- M N YGM L GR N LSQLCHEI L QKESLGLEICKNF LD QCPKFQ E QN ski LPKS R ayqv 647
Cdd:PRK13412 492 -------- SAY A N LA RLY A QRE afrk A N WRA L AA N HEKSVFYQ L DLADAAEDFVRLL LD MPEILP E DA --- PLML R ---- 556
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 648 evdl LRACGDE A KAIE L EHK vwg AVA EE TAS A V R Y g F R EH LL ESSGKSHSENHIS hpdr V FQPRRTKVEL PVR V D FV GGW 727
Cdd:PRK13412 557 ---- IHNRMFR A RILK L SGA --- RYR EE EQA A F R L - L R DG LL DGAYPRKQTPKLE ---- V YSDQIVWGRS PVR I D LA GGW 624
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 728 S DTPP WS L ERA G Y V L N M AI T L E G SL P IGTIIETTNQMG I SIQ - D D A G NELHIEDPISIKTPFE V ND PF RLV K S AL LVT G I 806
Cdd:PRK13412 625 T DTPP YC L YSG G N V V N L AI E L N G QP P LQVYVKPCSEPH I VLR s I D L G AMEVVRTNEELRDYKK V GS PF SIP K A AL CLA G F 704
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 807 VQENFVD S ------------ T G LA I KTW A NV P R GSGLGTSSILAA A V VKGLLQIS n G DESNE N - I ARLV LVLEQL MG TGG 873
Cdd:PRK13412 705 APRFSAE S yasleeqlkafg S G IE I TLL A AI P A GSGLGTSSILAA T V LGAISDFC - G LAWDK N e I CNRT LVLEQL LT TGG 783
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 874 GWQDQ I GG LY PG I K FTSSFP G IPMRLQ V VP L LA S PQLIS E LEQRL L VVF TG QV R L A HQV L HKV V TRYLQRDNLLISSIKR 953
Cdd:PRK13412 784 GWQDQ Y GG VL PG V K LLQTGA G FAQSPL V RW L PD S LFTQP E YRDCH L LYY TG IT R T A KGI L AEI V RSMFLNSTAHLQLLHE 863
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 954 LTEL A KSGR EA LMNC E VD E V G DIMSEA W RLHQE LD PYCSNEF V DKLF E FSQP Y SS G F KL V GAGGGG FSLIL AKD AEK A KE 1033
Cdd:PRK13412 864 MKAH A LDMY EA IQRG E FE E F G RLVGKT W EQNKA LD SGTNPAA V EAII E LIKD Y TL G Y KL P GAGGGG YLYMV AKD PGA A ER 943
....*....
gi 18378810 1034 L R QR L E E H A 1042
Cdd:PRK13412 944 I R KI L T E N A 952
Name
Accession
Description
Interval
E-value
Fucokinase
pfam07959 L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated ...
131-529
2.86e-153
L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated by L-fucokinase to form L-fucose-L-phosphate, which is then further converted to GDP-L-fucose in the reaction catalyzed by GDP-L-fucose pyrophosphorylase.
Pssm-ID: 462323
Cd Length: 405
Bit Score: 460.96
E-value: 2.86e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 131 AGG D S K R V P W A NPM GK V F LP LP Y laa D DP D GPV PL L F D HI LAI A S CARQ af QDQG G LFIMTG DV LPC FDA FKMTLPEDAA 210
Cdd:pfam07959 1 AGG Y S Q R L P S A SAL GK I F TA LP L --- E DP G GPV YQ L L D LK LAI Y S DFPS -- RMKP G VLVCST DV ILL FDA NEISFDKPGV 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 211 SIVTV P IT L D I AS NHGV I V TSKSE S LAESYTVS L VN D L L Q KP TV E D L VKKD A I L H DG RTL LD T GI ISAR G RAWSD L V AL G 290
Cdd:pfam07959 76 TALAH P SS L A I GT NHGV F V LDPQG S SEKDLEIG L CR D F L H KP SE E E L QASG A V L K DG FVY LD S GI VFFD G KTAEK L L AL Y 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 291 C S CQ P MIL E LIGSKKEMS LY E D LVA A WV P SRHDWLRT ------------ RP LG E L L VNS L GRQKMYSY C TYDLQ F L HFGT 358
Cdd:pfam07959 156 V S PG P LDC E TYLGPLQID LY G D FLQ A LG P GATLEYFL ntanvgkeeasl RP AR E E L WKL L RGTPLNVI C LPNSK F Y HFGT 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 359 SS E V L D HL S GD A S GI V GR rhlc SIPA T TV S D IA ------ A SSVILS S EIA PGVS I G ED S L I YDSTVS G A V Q IGS QS I VV G 432
Cdd:pfam07959 236 TA E Y L E HL T GD C S LR V EL ---- GLTS T AF S V IA narqlk A GASVIN S VLE PGVS V G PG S V I EYCHLG G P V S IGS GC I LS G 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 433 IHIP S ED lgtpes F R FM LPD RHC L WEV PL VGHK G -- R V I V YC G L HDN P K N S IH - KDG TF C GKPLE KV L FDL GI EES DLW S 509
Cdd:pfam07959 312 LDLS S SL ------ A R LE LPD DTF L HTL PL KLGG G kl Y V T V VF G I HDN L K S S VS d GNL TF L GKPLE DF L SLT GI QPE DLW F 385
410 420
....*....|....*....|
gi 18378810 510 S YVAQDRC LWNA K LFP ILTY 529
Cdd:pfam07959 386 S GEPREKS LWNA R LFP VCHD 405
fkp
PRK13412 bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
32-1042
6.23e-105
bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
Pssm-ID: 237379 [Multi-domain]
Cd Length: 974
Bit Score: 351.44
E-value: 6.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 32 PTWDAI V LTAA S P EQ AELYD W qlrrakrmgriasstvt LAVP DP D G KRI GSG AA T LNAIY A LA R HYEK l G F D LG pemeva 111
Cdd:PRK13412 31 SLPPNL V DSFH S L EQ VDRTE W ----------------- FCTS DP V G QKL GSG GG T TWLLE A CF R NGSP - G G D FT ------ 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 112 ngac K W vrf ISAKHVLM LHAGG D S K R V P WAN P M GK VFL P L P YLAA ddpd GPVPL L FDHI L AIASCARQAFQDQG ---- GL 187
Cdd:PRK13412 87 ---- E W --- LGKEKRIL LHAGG Q S R R L P GYA P S GK ILT P V P VFRW ---- ERGQR L SQNL L SLQLPLYERIMSKA pegl HT 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 188 F I MT GDV LPCFDAFKMTL PE da A SI V TVPITL D -- I A S NHGV I V T S KS eslaesy TVSLVNDL LQKP TV E D L vkk DAILH 265
Cdd:PRK13412 156 L I AS GDV YIRSEQPLQDI PE -- A DV V CYGLWV D ps L A T NHGV F V S S RK ------- SPERLDFM LQKP SL E E L --- GGLSK 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 266 DGRT L L D T GI ISARG RA WSD L VALG cscqpm IL E LI G SK K EMS LY E D LVA A ---- WVPSRHD wlrtrp L GE L L V NS L GRQ 341
Cdd:PRK13412 224 THLF L M D I GI WLLSD RA VEL L MKRS ------ GK E DG G KL K YYD LY S D FGL A lgth PRIGDDE ------ L NA L S V AI L PLP 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 342 KM ysyctydl Q F L H F GTS S E VLD ------ H L SG D ASG I VG R R hlcsipattv SDIAASSVILSSEIAPGVSIGEDS L - I Y 414
Cdd:PRK13412 292 GG -------- E F Y H Y GTS R E LIS stlavq N L VT D QRR I MH R K ---------- VKPHPAMFVQNAVLSGKLTAENAT L w I E 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 415 D S T V SGAVQIG S Q SI VV G I hipsedlgt PE - S FRFM LP DRH C LWE VP l VG HK G R V IVYC GL H D NP K NSIHKD - G T FC G K P 492
Cdd:PRK13412 354 N S H V GEGWKLA S R SI IT G V --------- PE n S WNLD LP EGV C IDV VP - VG DR G F V ARPY GL D D VF K GALADG k T T WF G R P 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 493 LEKVLFDL G IEES DL wssy VAQDRC L WN A K LFP IL T YS E M L - KLAS W LMGLDDS rn K E KIKL W RS S QRV S LE E L hgsinf 571
Cdd:PRK13412 424 FLEWMEAR G LSWP DL ---- KGRTDD L QA A H LFP VV T SV E E L g AVLR W MLSEPSL -- E E GKEI W LR S EKL S AD E I ------ 491
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 572 pemcngss NHQ A D LA GGI A KAC ---- M N YGM L GR N LSQLCHEI L QKESLGLEICKNF LD QCPKFQ E QN ski LPKS R ayqv 647
Cdd:PRK13412 492 -------- SAY A N LA RLY A QRE afrk A N WRA L AA N HEKSVFYQ L DLADAAEDFVRLL LD MPEILP E DA --- PLML R ---- 556
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 648 evdl LRACGDE A KAIE L EHK vwg AVA EE TAS A V R Y g F R EH LL ESSGKSHSENHIS hpdr V FQPRRTKVEL PVR V D FV GGW 727
Cdd:PRK13412 557 ---- IHNRMFR A RILK L SGA --- RYR EE EQA A F R L - L R DG LL DGAYPRKQTPKLE ---- V YSDQIVWGRS PVR I D LA GGW 624
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 728 S DTPP WS L ERA G Y V L N M AI T L E G SL P IGTIIETTNQMG I SIQ - D D A G NELHIEDPISIKTPFE V ND PF RLV K S AL LVT G I 806
Cdd:PRK13412 625 T DTPP YC L YSG G N V V N L AI E L N G QP P LQVYVKPCSEPH I VLR s I D L G AMEVVRTNEELRDYKK V GS PF SIP K A AL CLA G F 704
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 807 VQENFVD S ------------ T G LA I KTW A NV P R GSGLGTSSILAA A V VKGLLQIS n G DESNE N - I ARLV LVLEQL MG TGG 873
Cdd:PRK13412 705 APRFSAE S yasleeqlkafg S G IE I TLL A AI P A GSGLGTSSILAA T V LGAISDFC - G LAWDK N e I CNRT LVLEQL LT TGG 783
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 874 GWQDQ I GG LY PG I K FTSSFP G IPMRLQ V VP L LA S PQLIS E LEQRL L VVF TG QV R L A HQV L HKV V TRYLQRDNLLISSIKR 953
Cdd:PRK13412 784 GWQDQ Y GG VL PG V K LLQTGA G FAQSPL V RW L PD S LFTQP E YRDCH L LYY TG IT R T A KGI L AEI V RSMFLNSTAHLQLLHE 863
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 954 LTEL A KSGR EA LMNC E VD E V G DIMSEA W RLHQE LD PYCSNEF V DKLF E FSQP Y SS G F KL V GAGGGG FSLIL AKD AEK A KE 1033
Cdd:PRK13412 864 MKAH A LDMY EA IQRG E FE E F G RLVGKT W EQNKA LD SGTNPAA V EAII E LIKD Y TL G Y KL P GAGGGG YLYMV AKD PGA A ER 943
....*....
gi 18378810 1034 L R QR L E E H A 1042
Cdd:PRK13412 944 I R KI L T E N A 952
COG2605
COG2605 Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
718-1041
1.62e-61
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain]
Cd Length: 328
Bit Score: 212.73
E-value: 1.62e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 718 P V R VD F V GG WS D T PP WS LE RA G Y VLN M AI tleg SLPIGTII E TTNQMG I SIQ - D D AGNELHIEDPIS I ktpfevnd P FRL 796
Cdd:COG2605 6 P L R IS F A GG GT D L PP YY LE HG G A VLN A AI ---- DKYAYVTL E PRFDGK I RLS s S D TERVETVDEDDD I -------- P HPV 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 797 VKS AL LVT GI vqenfvd ST GL A I K T WANV P R GSGLG T SS I L AA A VVKG L LQISNGDE S NENI ARL VLVL E Q - LM G TG GG W 875
Cdd:COG2605 74 IRE AL KLF GI ------- GD GL E I T T DSDA P A GSGLG S SS A L TV A LLNA L HALLGLPL S PYDL ARL AYEI E R n DL G EP GG K 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 876 QDQ IGGLYP G IK F TSSF P G ip M R LQ V V PL LA SP QLIS ELE QR LL VVF TG QV R LAHQV L HKV V TRYLQR D NLLISSIKRLT 955
Cdd:COG2605 147 QDQ YAAAFG G FN F IEFG P D -- G R VI V N PL RI SP EILN ELE SN LL LFY TG IT R ESSDI L KEQ V KNVEDG D EATLEALHEMK 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 956 ELA KSGR EAL MNCEV DE V G DIMS E A W R L HQE L DPYC SN EFV D KLF E FS - QPYSS G F KL V GAGGGGF S L IL A KD a E KAKEL 1034
Cdd:COG2605 225 ELA LEMK EAL LKGDL DE F G ELLN E G W E L KKR L ASGI SN PAI D EIY E LA r KAGAL G G KL L GAGGGGF L L FY A PP - E RREAV 303
....*..
gi 18378810 1035 R QR L EEH 1041
Cdd:COG2605 304 R EA L SKA 310
mevalon_kin
TIGR00549 mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ...
824-1024
6.19e-10
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain]
Cd Length: 273
Bit Score: 61.15
E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 824 NV P R G S GLG T S SIL A A A VVKG L LQISNGDE S N E NI A R L VLVL E QLM - G TGG G WQDQI --- GG L ypg IK F TSSFP gipmrl 899
Cdd:TIGR00549 86 EI P P G R GLG S S AAV A V A LIRA L ADYFGSEL S K E EL A E L ANEA E KIA h G KPS G IDTAT sts GG P --- VY F EKGEG ------ 156
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 900 q VVPL L A S PQL iseleq RLLVVF TG QVRLAHQVLHK V VTRYLQRDN L LI S SIKRLT EL AKSGRE AL MNCE V DEV G DI M SE 979
Cdd:TIGR00549 157 - EFTK L I S LDG ------ YFVIAD TG VSGSTKEAVAR V RQLLERFPE L ID S IMDAIG EL TLEAKA AL QDGD V ESL G EL M NI 229
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 18378810 980 AWR L HQE L D py C S NEFV D K L F E FSQPYSS - G F KL V GAGGGG FSLI L 1024
Cdd:TIGR00549 230 NQG L LKA L G -- V S HPKL D Q L V E IARKAGA l G A KL T GAGGGG CMIA L 273
GHMP_kinases_C
pfam08544 GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ...
962-1043
4.48e-09
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain]
Cd Length: 85
Bit Score: 54.40
E-value: 4.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 962 R EAL MNCEVD E V G DIMS E AWRLHQE L DPY - CSNEFV D K L F E FSQPYSS G F KL V G A GGG GFSLI L A KD AEK A K E LRQR L E E 1040
Cdd:pfam08544 2 L EAL LRGDLE E L G KLLT E SAESLEP L LVV g ILPPEL D E L L E ALLELGL G A KL S G S GGG PTVFA L F KD EDD A E E VARA L R E 81
...
gi 18378810 1041 HAE 1043
Cdd:pfam08544 82 AGK 84
Name
Accession
Description
Interval
E-value
Fucokinase
pfam07959 L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated ...
131-529
2.86e-153
L-fucokinase; In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated by L-fucokinase to form L-fucose-L-phosphate, which is then further converted to GDP-L-fucose in the reaction catalyzed by GDP-L-fucose pyrophosphorylase.
Pssm-ID: 462323
Cd Length: 405
Bit Score: 460.96
E-value: 2.86e-153
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 131 AGG D S K R V P W A NPM GK V F LP LP Y laa D DP D GPV PL L F D HI LAI A S CARQ af QDQG G LFIMTG DV LPC FDA FKMTLPEDAA 210
Cdd:pfam07959 1 AGG Y S Q R L P S A SAL GK I F TA LP L --- E DP G GPV YQ L L D LK LAI Y S DFPS -- RMKP G VLVCST DV ILL FDA NEISFDKPGV 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 211 SIVTV P IT L D I AS NHGV I V TSKSE S LAESYTVS L VN D L L Q KP TV E D L VKKD A I L H DG RTL LD T GI ISAR G RAWSD L V AL G 290
Cdd:pfam07959 76 TALAH P SS L A I GT NHGV F V LDPQG S SEKDLEIG L CR D F L H KP SE E E L QASG A V L K DG FVY LD S GI VFFD G KTAEK L L AL Y 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 291 C S CQ P MIL E LIGSKKEMS LY E D LVA A WV P SRHDWLRT ------------ RP LG E L L VNS L GRQKMYSY C TYDLQ F L HFGT 358
Cdd:pfam07959 156 V S PG P LDC E TYLGPLQID LY G D FLQ A LG P GATLEYFL ntanvgkeeasl RP AR E E L WKL L RGTPLNVI C LPNSK F Y HFGT 235
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 359 SS E V L D HL S GD A S GI V GR rhlc SIPA T TV S D IA ------ A SSVILS S EIA PGVS I G ED S L I YDSTVS G A V Q IGS QS I VV G 432
Cdd:pfam07959 236 TA E Y L E HL T GD C S LR V EL ---- GLTS T AF S V IA narqlk A GASVIN S VLE PGVS V G PG S V I EYCHLG G P V S IGS GC I LS G 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 433 IHIP S ED lgtpes F R FM LPD RHC L WEV PL VGHK G -- R V I V YC G L HDN P K N S IH - KDG TF C GKPLE KV L FDL GI EES DLW S 509
Cdd:pfam07959 312 LDLS S SL ------ A R LE LPD DTF L HTL PL KLGG G kl Y V T V VF G I HDN L K S S VS d GNL TF L GKPLE DF L SLT GI QPE DLW F 385
410 420
....*....|....*....|
gi 18378810 510 S YVAQDRC LWNA K LFP ILTY 529
Cdd:pfam07959 386 S GEPREKS LWNA R LFP VCHD 405
fkp
PRK13412 bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
32-1042
6.23e-105
bifunctional fucokinase/L-fucose-1-P-guanylyltransferase; Provisional
Pssm-ID: 237379 [Multi-domain]
Cd Length: 974
Bit Score: 351.44
E-value: 6.23e-105
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 32 PTWDAI V LTAA S P EQ AELYD W qlrrakrmgriasstvt LAVP DP D G KRI GSG AA T LNAIY A LA R HYEK l G F D LG pemeva 111
Cdd:PRK13412 31 SLPPNL V DSFH S L EQ VDRTE W ----------------- FCTS DP V G QKL GSG GG T TWLLE A CF R NGSP - G G D FT ------ 86
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 112 ngac K W vrf ISAKHVLM LHAGG D S K R V P WAN P M GK VFL P L P YLAA ddpd GPVPL L FDHI L AIASCARQAFQDQG ---- GL 187
Cdd:PRK13412 87 ---- E W --- LGKEKRIL LHAGG Q S R R L P GYA P S GK ILT P V P VFRW ---- ERGQR L SQNL L SLQLPLYERIMSKA pegl HT 155
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 188 F I MT GDV LPCFDAFKMTL PE da A SI V TVPITL D -- I A S NHGV I V T S KS eslaesy TVSLVNDL LQKP TV E D L vkk DAILH 265
Cdd:PRK13412 156 L I AS GDV YIRSEQPLQDI PE -- A DV V CYGLWV D ps L A T NHGV F V S S RK ------- SPERLDFM LQKP SL E E L --- GGLSK 223
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 266 DGRT L L D T GI ISARG RA WSD L VALG cscqpm IL E LI G SK K EMS LY E D LVA A ---- WVPSRHD wlrtrp L GE L L V NS L GRQ 341
Cdd:PRK13412 224 THLF L M D I GI WLLSD RA VEL L MKRS ------ GK E DG G KL K YYD LY S D FGL A lgth PRIGDDE ------ L NA L S V AI L PLP 291
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 342 KM ysyctydl Q F L H F GTS S E VLD ------ H L SG D ASG I VG R R hlcsipattv SDIAASSVILSSEIAPGVSIGEDS L - I Y 414
Cdd:PRK13412 292 GG -------- E F Y H Y GTS R E LIS stlavq N L VT D QRR I MH R K ---------- VKPHPAMFVQNAVLSGKLTAENAT L w I E 353
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 415 D S T V SGAVQIG S Q SI VV G I hipsedlgt PE - S FRFM LP DRH C LWE VP l VG HK G R V IVYC GL H D NP K NSIHKD - G T FC G K P 492
Cdd:PRK13412 354 N S H V GEGWKLA S R SI IT G V --------- PE n S WNLD LP EGV C IDV VP - VG DR G F V ARPY GL D D VF K GALADG k T T WF G R P 423
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 493 LEKVLFDL G IEES DL wssy VAQDRC L WN A K LFP IL T YS E M L - KLAS W LMGLDDS rn K E KIKL W RS S QRV S LE E L hgsinf 571
Cdd:PRK13412 424 FLEWMEAR G LSWP DL ---- KGRTDD L QA A H LFP VV T SV E E L g AVLR W MLSEPSL -- E E GKEI W LR S EKL S AD E I ------ 491
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 572 pemcngss NHQ A D LA GGI A KAC ---- M N YGM L GR N LSQLCHEI L QKESLGLEICKNF LD QCPKFQ E QN ski LPKS R ayqv 647
Cdd:PRK13412 492 -------- SAY A N LA RLY A QRE afrk A N WRA L AA N HEKSVFYQ L DLADAAEDFVRLL LD MPEILP E DA --- PLML R ---- 556
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 648 evdl LRACGDE A KAIE L EHK vwg AVA EE TAS A V R Y g F R EH LL ESSGKSHSENHIS hpdr V FQPRRTKVEL PVR V D FV GGW 727
Cdd:PRK13412 557 ---- IHNRMFR A RILK L SGA --- RYR EE EQA A F R L - L R DG LL DGAYPRKQTPKLE ---- V YSDQIVWGRS PVR I D LA GGW 624
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 728 S DTPP WS L ERA G Y V L N M AI T L E G SL P IGTIIETTNQMG I SIQ - D D A G NELHIEDPISIKTPFE V ND PF RLV K S AL LVT G I 806
Cdd:PRK13412 625 T DTPP YC L YSG G N V V N L AI E L N G QP P LQVYVKPCSEPH I VLR s I D L G AMEVVRTNEELRDYKK V GS PF SIP K A AL CLA G F 704
810 820 830 840 850 860 870 880
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 807 VQENFVD S ------------ T G LA I KTW A NV P R GSGLGTSSILAA A V VKGLLQIS n G DESNE N - I ARLV LVLEQL MG TGG 873
Cdd:PRK13412 705 APRFSAE S yasleeqlkafg S G IE I TLL A AI P A GSGLGTSSILAA T V LGAISDFC - G LAWDK N e I CNRT LVLEQL LT TGG 783
890 900 910 920 930 940 950 960
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 874 GWQDQ I GG LY PG I K FTSSFP G IPMRLQ V VP L LA S PQLIS E LEQRL L VVF TG QV R L A HQV L HKV V TRYLQRDNLLISSIKR 953
Cdd:PRK13412 784 GWQDQ Y GG VL PG V K LLQTGA G FAQSPL V RW L PD S LFTQP E YRDCH L LYY TG IT R T A KGI L AEI V RSMFLNSTAHLQLLHE 863
970 980 990 1000 1010 1020 1030 1040
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 954 LTEL A KSGR EA LMNC E VD E V G DIMSEA W RLHQE LD PYCSNEF V DKLF E FSQP Y SS G F KL V GAGGGG FSLIL AKD AEK A KE 1033
Cdd:PRK13412 864 MKAH A LDMY EA IQRG E FE E F G RLVGKT W EQNKA LD SGTNPAA V EAII E LIKD Y TL G Y KL P GAGGGG YLYMV AKD PGA A ER 943
....*....
gi 18378810 1034 L R QR L E E H A 1042
Cdd:PRK13412 944 I R KI L T E N A 952
COG2605
COG2605 Predicted kinase related to galactokinase and mevalonate kinase [General function prediction ...
718-1041
1.62e-61
Predicted kinase related to galactokinase and mevalonate kinase [General function prediction only];
Pssm-ID: 442017 [Multi-domain]
Cd Length: 328
Bit Score: 212.73
E-value: 1.62e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 718 P V R VD F V GG WS D T PP WS LE RA G Y VLN M AI tleg SLPIGTII E TTNQMG I SIQ - D D AGNELHIEDPIS I ktpfevnd P FRL 796
Cdd:COG2605 6 P L R IS F A GG GT D L PP YY LE HG G A VLN A AI ---- DKYAYVTL E PRFDGK I RLS s S D TERVETVDEDDD I -------- P HPV 73
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 797 VKS AL LVT GI vqenfvd ST GL A I K T WANV P R GSGLG T SS I L AA A VVKG L LQISNGDE S NENI ARL VLVL E Q - LM G TG GG W 875
Cdd:COG2605 74 IRE AL KLF GI ------- GD GL E I T T DSDA P A GSGLG S SS A L TV A LLNA L HALLGLPL S PYDL ARL AYEI E R n DL G EP GG K 146
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 876 QDQ IGGLYP G IK F TSSF P G ip M R LQ V V PL LA SP QLIS ELE QR LL VVF TG QV R LAHQV L HKV V TRYLQR D NLLISSIKRLT 955
Cdd:COG2605 147 QDQ YAAAFG G FN F IEFG P D -- G R VI V N PL RI SP EILN ELE SN LL LFY TG IT R ESSDI L KEQ V KNVEDG D EATLEALHEMK 224
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 956 ELA KSGR EAL MNCEV DE V G DIMS E A W R L HQE L DPYC SN EFV D KLF E FS - QPYSS G F KL V GAGGGGF S L IL A KD a E KAKEL 1034
Cdd:COG2605 225 ELA LEMK EAL LKGDL DE F G ELLN E G W E L KKR L ASGI SN PAI D EIY E LA r KAGAL G G KL L GAGGGGF L L FY A PP - E RREAV 303
....*..
gi 18378810 1035 R QR L EEH 1041
Cdd:COG2605 304 R EA L SKA 310
ERG12
COG1577 Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway ...
766-1025
2.62e-17
Mevalonate kinase [Lipid transport and metabolism]; Mevalonate kinase is part of the Pathway/BioSystem: Isoprenoid biosynthesis
Pssm-ID: 441185 [Multi-domain]
Cd Length: 277
Bit Score: 83.35
E-value: 2.62e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 766 ISIQ DD AGNELHIE D - PISIKTPFEVNDPF R LV K S A L lvt GIVQ E NF - VDST G LA I KTWANV PR GS GLG T S SIL A A AV VK 843
Cdd:COG1577 32 VEPS DD DKLRIESP D l GGTLDLDPLADAAL R YI K A A I --- EAAL E YL g LPLK G FD I EIDSEI PR KR GLG S S AAV A V AV IR 108
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 844 G L LQISNGDE S N E NIAR L V L VL E QLM - G TGG G w Q D Q igglypgik FT S SFP G i P MRL Q vvplla SPQLISE LE Q ---- R L 918
Cdd:COG1577 109 A L AAFYGVEL S K E ELFK L A L EA E KIV h G NPS G - L D T --------- AA S TYG G - P IYY Q ------ RGDRAEP LE L pknl P L 171
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 919 L V VF TG QVRLAHQVLH KV VTRYLQRDN L LISSIKRLTE L AKSGR EAL MNCEVDEV G DI M S E AWR L HQE L D py C S NEFV D K 998
Cdd:COG1577 172 V V GD TG VPASTKELVA KV RKLKERNPE L YEAFLEEIGD L VEEAI EAL EEGDLEAL G EL M N E NHG L LRA L G -- V S TPEL D R 249
250 260
....*....|....*....|....*...
gi 18378810 999 L F E FSQPYS - S G F KL V GAGGGG FSLI LA 1025
Cdd:COG1577 250 L V E AARKAG a L G A KL T GAGGGG CVIA LA 277
mevalon_kin
TIGR00549 mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate ...
824-1024
6.19e-10
mevalonate kinase; This model represents mevalonate kinase, the third step in the mevalonate pathway of isopentanyl pyrophosphate (IPP) biosynthesis. IPP is a common intermediate for a number of pathways including cholesterol biosynthesis. This model covers enzymes from eukaryotes, archaea and bacteria. The related enzyme from the same pathway, phosphmevalonate kinase, serves as an outgroup for this clade. Paracoccus exhibits two genes within the phosphomevalonate/mevalonate kinase family, one of which falls between trusted and noise cutoffs of this model. The degree of divergence is high, but if the trees created from this model are correct, the proper names of these genes have been swapped. [Central intermediary metabolism, Other]
Pssm-ID: 273130 [Multi-domain]
Cd Length: 273
Bit Score: 61.15
E-value: 6.19e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 824 NV P R G S GLG T S SIL A A A VVKG L LQISNGDE S N E NI A R L VLVL E QLM - G TGG G WQDQI --- GG L ypg IK F TSSFP gipmrl 899
Cdd:TIGR00549 86 EI P P G R GLG S S AAV A V A LIRA L ADYFGSEL S K E EL A E L ANEA E KIA h G KPS G IDTAT sts GG P --- VY F EKGEG ------ 156
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 900 q VVPL L A S PQL iseleq RLLVVF TG QVRLAHQVLHK V VTRYLQRDN L LI S SIKRLT EL AKSGRE AL MNCE V DEV G DI M SE 979
Cdd:TIGR00549 157 - EFTK L I S LDG ------ YFVIAD TG VSGSTKEAVAR V RQLLERFPE L ID S IMDAIG EL TLEAKA AL QDGD V ESL G EL M NI 229
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 18378810 980 AWR L HQE L D py C S NEFV D K L F E FSQPYSS - G F KL V GAGGGG FSLI L 1024
Cdd:TIGR00549 230 NQG L LKA L G -- V S HPKL D Q L V E IARKAGA l G A KL T GAGGGG CMIA L 273
GHMP_kinases_C
pfam08544 GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and ...
962-1043
4.48e-09
GHMP kinases C terminal; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 430063 [Multi-domain]
Cd Length: 85
Bit Score: 54.40
E-value: 4.48e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 962 R EAL MNCEVD E V G DIMS E AWRLHQE L DPY - CSNEFV D K L F E FSQPYSS G F KL V G A GGG GFSLI L A KD AEK A K E LRQR L E E 1040
Cdd:pfam08544 2 L EAL LRGDLE E L G KLLT E SAESLEP L LVV g ILPPEL D E L L E ALLELGL G A KL S G S GGG PTVFA L F KD EDD A E E VARA L R E 81
...
gi 18378810 1041 HAE 1043
Cdd:pfam08544 82 AGK 84
PRK03817
PRK03817 galactokinase; Provisional
713-1040
8.45e-08
galactokinase; Provisional
Pssm-ID: 235163 [Multi-domain]
Cd Length: 351
Bit Score: 55.39
E-value: 8.45e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 713 T KV EL P V RV DFV G GWS D tpp WSL era GYVL NM AI T L egslpi G T II E TTNQMGISIQDDAG NE lhiedpisi KTP FE VND 792
Cdd:PRK03817 1 M KV KS P G RV NLI G EHT D --- YND --- GYVL PF AI N L ------ Y T FL E IEKSEKFIFYSENF NE --------- EKT FE LDK 59
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 793 PFR L VKS A LLVT G I --- VQENFVDST G LAI K TWA N V P R G S GL GT S SI L AA AV VKG L LQIS N GDE S NENI A R L VLVL E - QL 868
Cdd:PRK03817 60 LEK L NSW A DYIK G V iwv LEKRGYEVG G VKG K VSS N L P I G A GL SS S AS L EV AV AYA L NEAY N LNL S KLEL A L L AREA E n EF 139
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 869 M G TGG G WQ DQ igglypgik F TSS F --------- PGIPMRLQV VP L las P QLIS eleqr L LV VF TG --------------- 924
Cdd:PRK03817 140 V G VPC G IM DQ --------- F AVA F gkkdhaifl DTMTLEYEY VP F --- P EDYE ----- I LV FD TG vkrelasseynerrq 202
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 925 QVRL A HQV L H K VVTRYLQRDN L -- L ISSIKR ----- L T E LAK -- SG R E AL MNCEVDEV G DIMS E A wrl H QE L - D P Y - C S N 993
Cdd:PRK03817 203 ECEE A LKI L G K KSSKEVTEED L sk L PPLLRK ragyv L R E NER vl KV R D AL KEGDIETL G ELLT E S --- H WD L a D N Y e V S C 279
330 340 350 360
....*....|....*....|....*....|....*....|....*...
gi 18378810 994 E FV D KLF EF SQPYSS - G FK L V GAG G GG f S L I LAK D AE K AKELRQR L E E 1040
Cdd:PRK03817 280 E EL D FFV EF ALELGA y G AR L T GAG F GG - S A I ALV D KG K FESIGEE L L E 326
GHMP_kinases_N
pfam00288 GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and ...
819-885
1.08e-07
GHMP kinases N terminal domain; This family includes homoserine kinases, galactokinases and mevalonate kinases.
Pssm-ID: 395225 [Multi-domain]
Cd Length: 64
Bit Score: 49.47
E-value: 1.08e-07
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18378810 819 I KTWA N V P R G S GLG T S SI LA A A VVKG L LQI sngde SNENI A R L V L VL E Q L M G T G - GG WQ D QIGG LY P G 885
Cdd:pfam00288 2 I EIES N I P L G A GLG S S AA LA V A LLLA L NEL ----- FGLPL A K L A L EA E E L A G G G r GG GM D VAAS LY G G 64
PTZ00298
PTZ00298 mevalonate kinase; Provisional
953-1054
6.25e-03
mevalonate kinase; Provisional
Pssm-ID: 240351 [Multi-domain]
Cd Length: 328
Bit Score: 40.22
E-value: 6.25e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18378810 953 RLTELAKSGR EAL MNCEVDE VG DI M SEAWR L H Q E L DPY C SN ef V D KLFEFSQP Y SS - G F K LV G A G G GG FSLI LA KDAEK - 1030
Cdd:PTZ00298 222 NYNACVSEAK EAL QKGNLFR VG EL M NANHD L C Q K L TVS C RE -- L D SIVQTCRT Y GA l G A K MS G T G R GG LVVA LA ASEDQ r 299
90 100
....*....|....*....|....*..
gi 18378810 1031 --- AK EL R Q R LE E h A E F dvk V YNWSIC 1054
Cdd:PTZ00298 300 dai AK AV R A R CP E - A K F --- V WRYTVQ 322
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
