|
Name |
Accession |
Description |
Interval |
E-value |
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
480-654 |
1.79e-28 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 111.69 E-value: 1.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 480 DVISIDVDaadkSSSVRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYIMDAEKGESGglwRLTEGAWTDTMCNWSP 559
Cdd:COG0823 12 DIYVVDLD----GGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPR---RLTFGGGYNASPSWSP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 560 DGEWIAFASDREspgsGSFELFLIHPNGTGLRKLIQSgtggrTNHPIFSPDSKSLVFTSDYAGisaepisnphhyqpYGD 639
Cdd:COG0823 85 DGKRLAFVSRSD----GRFDIYVLDLDGGAPRRLTDG-----PGSPSWSPDGRRIVFSSDRGG--------------RPD 141
|
170
....*....|....*
gi 18395019 640 IFTVKLDGsNVRRLT 654
Cdd:COG0823 142 LYVVDLDG-RKRRLT 155
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
423-670 |
1.79e-24 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 106.59 E-value: 1.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 423 DRIAYVKMPG------VFVVKPDGSGQREVYKG--MAFSTAWDPVRPGIVYSSsgptFATERTEVDVISIdvdaadKSSS 494
Cdd:TIGR02800 156 TRIAYVSKSGksrryeLQVADYDGANPQTITRSrePILSPAWSPDGQKLAYVS----FESGKPEIYVQDL------ATGQ 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 495 VRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYIMDAEkgeSGGLWRLTEGAWTDTMCNWSPDGEWIAFASDRespg 574
Cdd:TIGR02800 226 REKVASFPGMNGAPAFSPDGSKLAVSLSKDGNPDIYVMDLD---GKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDR---- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 575 SGSFELFLIHPNGTGLRKLiqSGTGGRTNHPIFSPDSKSLVFTSDYAGIsaepisnpHHyqpygdIFTVKLDGSNVRRLT 654
Cdd:TIGR02800 299 GGSPQIYMMDADGGEVRRL--TFRGGYNASPSWSPDGDLIAFVHREGGG--------FN------IAVMDLDGGGERVLT 362
|
250
....*....|....*...
gi 18395019 655 HNSYEDGtPAWAP--RFI 670
Cdd:TIGR02800 363 DTGLDES-PSFAPngRMI 379
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
169-619 |
1.06e-18 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 91.25 E-value: 1.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 169 GEFIVYVSTHESsgePRASWTAVYSTELKTGLTRRLtPSGVAdFSPAVSPSGNLTAVASYG--ERGW---TGEVeelRTD 243
Cdd:COG4946 116 GKSVLFASNRGS---PPSRSNQLYTVPVDGGLPERL-PLPPA-GDGSFSPDGKKLAYTRIGreFRTWkryRGGT---AGD 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 244 IYVFLTRDGSHRvKVVEHGG---WPCWVDEsTLYFhrRSEEDGWISVYRaILPENGplttesvTIQRVTppgvhaftpat 320
Cdd:COG4946 188 IWIYDLGTGEFT-RLTDFGGndrNPMWIGD-RIYF--LSDRDGTFNLYS-YDPDGK-------DLRQLT----------- 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 321 spNNHEF-VavatRRPGSDYRHV--E------LFDLKRNE----FIELTR-LVAPKSHHLNPF-------LSPDSSRVGY 379
Cdd:COG4946 245 --HFKDFdV----RFPSTDGGRIvyEqggdlyLLDLASGEprklNITLAGdFPQRRPRWVDVSgyltsfaLSPDGKRVAF 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 380 hSCRGDangrrsplLFLeniqTTTRDLSLFRIDGS------FPSFSPGGDRIAYVKmpgvfvvkpDGSGQREVYkgmafs 453
Cdd:COG4946 319 -EARGE--------VFT----VPAEKGPTRNLTNTpgvrerLPAWSPDGKSIAYFS---------DASGEYELY------ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 454 tawdpVRPgivysssgptfatertevdvisidvdaADKSSSVRRLTTNGKNNAF-PWPSPDGKRIVFRSGRTghkNLYIM 532
Cdd:COG4946 371 -----IAP---------------------------ADGSGEPKQLTLGDLGRVFnPVWSPDGKKIAFTDNRG---RLWVV 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 533 DAEKGESgglwR--LTEGAWTDTM-CNWSPDGEWIAFASDRESPGSgsfELFLIHPNGTGLRKLiqsgTGGRTN--HPIF 607
Cdd:COG4946 416 DLASGKV----RkvDTDGYGDGISdLAWSPDSKWLAYSKPGPNQLS---QIFLYDVETGKTVQL----TDGRYDdgSPAF 484
|
490
....*....|..
gi 18395019 608 SPDSKSLVFTSD 619
Cdd:COG4946 485 SPDGKYLYFLSS 496
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
357-599 |
3.94e-05 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 46.68 E-value: 3.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 357 RLVAPKSHHLNPFLSPDSSRVGYHScrgDANGrrSPLLFLENIQTTT-------RDLS-LFRIDGSfPSFSPGGDRIayv 428
Cdd:PRK01029 225 KILALQGNQLMPTFSPRKKLLAFIS---DRYG--NPDLFIQSFSLETgaigkprRLLNeAFGTQGN-PSFSPDGTRL--- 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 429 kmpgVFVVKPDGsgqrevykgmafstawdpvRPGIVysssgptfatertevdVISIDvdaaDKSSSVRRLTTNGKNNAFP 508
Cdd:PRK01029 296 ----VFVSNKDG-------------------RPRIY----------------IMQID----PEGQSPRLLTKKYRNSSCP 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 509 WPSPDGKRIVFRSGRTGHKNLYIMDAEKGESgglWRLTEGAWTDTMCNWSPDGEWIAFASDrespGSGSFELFLIHPNGT 588
Cdd:PRK01029 333 AWSPDGKKIAFCSVIKGVRQICVYDLATGRD---YQLTTSPENKESPSWAIDSLHLVYSAG----NSNESELYLISLITK 405
|
250
....*....|.
gi 18395019 589 GLRKlIQSGTG 599
Cdd:PRK01029 406 KTRK-IVIGSG 415
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
495-531 |
6.01e-05 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 40.58 E-value: 6.01e-05
10 20 30
....*....|....*....|....*....|....*..
gi 18395019 495 VRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYI 531
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| tolB |
PRK04043 |
Tol-Pal system protein TolB; |
513-625 |
1.45e-04 |
|
Tol-Pal system protein TolB;
Pssm-ID: 235212 [Multi-domain] Cd Length: 419 Bit Score: 44.98 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 513 DGKRIVFRSGRTGHKNLYIMDAEkgeSGGLWRLTEGAWTDTMCnwSPDGEWIAFASdRESP---GSGSFELFLIHPNGTG 589
Cdd:PRK04043 287 DDKRIVFVSDRLGYPNIFMKKLN---SGSVEQVVFHGKNNSSV--STYKNYIVYSS-RETNnefGKNTFNLYLISTNSDY 360
|
90 100 110
....*....|....*....|....*....|....*.
gi 18395019 590 LRKLIqsgTGGRTNHPIFSPDSKSLVFTSDYAGISA 625
Cdd:PRK04043 361 IRRLT---ANGVNQFPRFSSDGGSIMFIKYLGNQSA 393
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
480-654 |
1.79e-28 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 111.69 E-value: 1.79e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 480 DVISIDVDaadkSSSVRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYIMDAEKGESGglwRLTEGAWTDTMCNWSP 559
Cdd:COG0823 12 DIYVVDLD----GGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGPQIYVVDADGGEPR---RLTFGGGYNASPSWSP 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 560 DGEWIAFASDREspgsGSFELFLIHPNGTGLRKLIQSgtggrTNHPIFSPDSKSLVFTSDYAGisaepisnphhyqpYGD 639
Cdd:COG0823 85 DGKRLAFVSRSD----GRFDIYVLDLDGGAPRRLTDG-----PGSPSWSPDGRRIVFSSDRGG--------------RPD 141
|
170
....*....|....*
gi 18395019 640 IFTVKLDGsNVRRLT 654
Cdd:COG0823 142 LYVVDLDG-RKRRLT 155
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
517-667 |
6.47e-27 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 107.07 E-value: 6.47e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 517 IVFRSGRTGHKNLYIMDAEkgeSGGLWRLTEGAWTDTMCNWSPDGEWIAFASDRespgSGSFELFLIHPNGTGLRKLiqS 596
Cdd:COG0823 1 LAFTLSRDGNSDIYVVDLD---GGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDR----GGGPQIYVVDADGGEPRRL--T 71
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18395019 597 GTGGRTNHPIFSPDSKSLVFTSDYAGisaepisnphhyqpYGDIFTVKLDGSNVRRLTHNSYEdgtPAWAP 667
Cdd:COG0823 72 FGGGYNASPSWSPDGKRLAFVSRSDG--------------RFDIYVLDLDGGAPRRLTDGPGS---PSWSP 125
|
|
| propeller_TolB |
TIGR02800 |
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB ... |
423-670 |
1.79e-24 |
|
tol-pal system beta propeller repeat protein TolB; Members of this protein family are the TolB periplasmic protein of Gram-negative bacteria. TolB is part of the Tol-Pal (peptidoglycan-associated lipoprotein) multiprotein complex, comprising five envelope proteins, TolQ, TolR, TolA, TolB and Pal, which form two complexes. The TolQ, TolR and TolA inner-membrane proteins interact via their transmembrane domains. The {beta}-propeller domain of the periplasmic protein TolB is responsible for its interaction with Pal. TolB also interacts with the outer-membrane peptidoglycan-associated proteins Lpp and OmpA. TolA undergoes a conformational change in response to changes in the proton-motive force, and interacts with Pal in an energy-dependent manner. The C-terminal periplasmic domain of TolA also interacts with the N-terminal domain of TolB. The Tol-PAL system is required for bacterial outer membrane integrity. E. coli TolB is involved in the tonB-independent uptake of group A colicins (colicins A, E1, E2, E3 and K), and is necessary for the colicins to reach their respective targets after initial binding to the bacteria. It is also involved in uptake of filamentous DNA. Study of its structure suggest that the TolB protein might be involved in the recycling of peptidoglycan or in its covalent linking with lipoproteins. The Tol-Pal system is also implicated in pathogenesis of E. coli, Haemophilus ducreyi , Salmonella enterica and Vibrio cholerae, but the mechanism(s) is unclear. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]
Pssm-ID: 274305 [Multi-domain] Cd Length: 417 Bit Score: 106.59 E-value: 1.79e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 423 DRIAYVKMPG------VFVVKPDGSGQREVYKG--MAFSTAWDPVRPGIVYSSsgptFATERTEVDVISIdvdaadKSSS 494
Cdd:TIGR02800 156 TRIAYVSKSGksrryeLQVADYDGANPQTITRSrePILSPAWSPDGQKLAYVS----FESGKPEIYVQDL------ATGQ 225
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 495 VRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYIMDAEkgeSGGLWRLTEGAWTDTMCNWSPDGEWIAFASDRespg 574
Cdd:TIGR02800 226 REKVASFPGMNGAPAFSPDGSKLAVSLSKDGNPDIYVMDLD---GKQLTRLTNGPGIDTEPSWSPDGKSIAFTSDR---- 298
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 575 SGSFELFLIHPNGTGLRKLiqSGTGGRTNHPIFSPDSKSLVFTSDYAGIsaepisnpHHyqpygdIFTVKLDGSNVRRLT 654
Cdd:TIGR02800 299 GGSPQIYMMDADGGEVRRL--TFRGGYNASPSWSPDGDLIAFVHREGGG--------FN------IAVMDLDGGGERVLT 362
|
250
....*....|....*...
gi 18395019 655 HNSYEDGtPAWAP--RFI 670
Cdd:TIGR02800 363 DTGLDES-PSFAPngRMI 379
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
414-588 |
9.51e-21 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 89.35 E-value: 9.51e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 414 SFPSFSPGGDRIAYVKmpgvfvvkpDGSGQREVYKgmafstawdpvrpgivysssgptfatertevdvisIDVDaadkSS 493
Cdd:COG0823 34 TSPAWSPDGRRIAFTS---------DRGGGPQIYV-----------------------------------VDAD----GG 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 494 SVRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYIMDAekgESGGLWRLTEGAWTDTmcnWSPDGEWIAFASDResp 573
Cdd:COG0823 66 EPRRLTFGGGYNASPSWSPDGKRLAFVSRSDGRFDIYVLDL---DGGAPRRLTDGPGSPS---WSPDGRRIVFSSDR--- 136
|
170
....*....|....*
gi 18395019 574 gSGSFELFLIHPNGT 588
Cdd:COG0823 137 -GGRPDLYVVDLDGR 150
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
169-619 |
1.06e-18 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 91.25 E-value: 1.06e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 169 GEFIVYVSTHESsgePRASWTAVYSTELKTGLTRRLtPSGVAdFSPAVSPSGNLTAVASYG--ERGW---TGEVeelRTD 243
Cdd:COG4946 116 GKSVLFASNRGS---PPSRSNQLYTVPVDGGLPERL-PLPPA-GDGSFSPDGKKLAYTRIGreFRTWkryRGGT---AGD 187
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 244 IYVFLTRDGSHRvKVVEHGG---WPCWVDEsTLYFhrRSEEDGWISVYRaILPENGplttesvTIQRVTppgvhaftpat 320
Cdd:COG4946 188 IWIYDLGTGEFT-RLTDFGGndrNPMWIGD-RIYF--LSDRDGTFNLYS-YDPDGK-------DLRQLT----------- 244
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 321 spNNHEF-VavatRRPGSDYRHV--E------LFDLKRNE----FIELTR-LVAPKSHHLNPF-------LSPDSSRVGY 379
Cdd:COG4946 245 --HFKDFdV----RFPSTDGGRIvyEqggdlyLLDLASGEprklNITLAGdFPQRRPRWVDVSgyltsfaLSPDGKRVAF 318
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 380 hSCRGDangrrsplLFLeniqTTTRDLSLFRIDGS------FPSFSPGGDRIAYVKmpgvfvvkpDGSGQREVYkgmafs 453
Cdd:COG4946 319 -EARGE--------VFT----VPAEKGPTRNLTNTpgvrerLPAWSPDGKSIAYFS---------DASGEYELY------ 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 454 tawdpVRPgivysssgptfatertevdvisidvdaADKSSSVRRLTTNGKNNAF-PWPSPDGKRIVFRSGRTghkNLYIM 532
Cdd:COG4946 371 -----IAP---------------------------ADGSGEPKQLTLGDLGRVFnPVWSPDGKKIAFTDNRG---RLWVV 415
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 533 DAEKGESgglwR--LTEGAWTDTM-CNWSPDGEWIAFASDRESPGSgsfELFLIHPNGTGLRKLiqsgTGGRTN--HPIF 607
Cdd:COG4946 416 DLASGKV----RkvDTDGYGDGISdLAWSPDSKWLAYSKPGPNQLS---QIFLYDVETGKTVQL----TDGRYDdgSPAF 484
|
490
....*....|..
gi 18395019 608 SPDSKSLVFTSD 619
Cdd:COG4946 485 SPDGKYLYFLSS 496
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
496-665 |
2.00e-18 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 90.10 E-value: 2.00e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 496 RRLTTNGKNNAFP-WpSPDGKRIVFRSGRTGHKNLYIMDAEKGEsggLWRLT-EGAwTDTMCNWSPDGEWIAFASDRESP 573
Cdd:COG4946 54 RRLTSHPGYESFPrF-SPDGKWIAFTSDYDGNTDVYVMPAEGGE---PKRLTyHPA-NDRVVGWTPDGKSVLFASNRGSP 128
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 574 GSGSFELFLIHPNGtGLRKLIqsgTGGRTNHPIFSPDSKSLVFTS---------DYAGISAepisnphhyqpyGDIFTVK 644
Cdd:COG4946 129 PSRSNQLYTVPVDG-GLPERL---PLPPAGDGSFSPDGKKLAYTRigrefrtwkRYRGGTA------------GDIWIYD 192
|
170 180
....*....|....*....|.
gi 18395019 645 LDGSNVRRLTHNSYEDGTPAW 665
Cdd:COG4946 193 LGTGEFTRLTDFGGNDRNPMW 213
|
|
| COG4946 |
COG4946 |
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ... |
165-667 |
9.21e-15 |
|
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];
Pssm-ID: 443973 [Multi-domain] Cd Length: 1072 Bit Score: 78.54 E-value: 9.21e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 165 PSLSGEFIVYVSthessgepraswtA--VYSTELKTGLTRRLTPSGVADFSPAVSPSGNLTAvasygergWTGEvEELRT 242
Cdd:COG4946 28 PAISGDTIVFVY-------------AgdLWTVPADGGRARRLTSHPGYESFPRFSPDGKWIA--------FTSD-YDGNT 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 243 DIYVF---------LTRDGShRVKVVehgGW-PcwvDESTLYFH-RRSEEDGWISVYRAILPENGplttesvTIQRVTPP 311
Cdd:COG4946 86 DVYVMpaeggepkrLTYHPA-NDRVV---GWtP---DGKSVLFAsNRGSPPSRSNQLYTVPVDGG-------LPERLPLP 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 312 GvhAFTPATSPNNHefVAVATRRPGSD-----YRH-----VELFDLKRNEFielTRLVAPKSHHLNPFLSPDssRVGYHS 381
Cdd:COG4946 152 P--AGDGSFSPDGK--KLAYTRIGREFrtwkrYRGgtagdIWIYDLGTGEF---TRLTDFGGNDRNPMWIGD--RIYFLS 222
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 382 crgDANGRrspllflENI------QTTTRDLSLFRiDGS--FPSFSpgGDRIAYVKmpgvfvvkpDGsgqrEVYKgmafs 453
Cdd:COG4946 223 ---DRDGT-------FNLysydpdGKDLRQLTHFK-DFDvrFPSTD--GGRIVYEQ---------GG----DLYL----- 271
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 454 taWDPvrpgivysssgptfATERTEVdvISIDVdAADKSSSVRRLTTNGKNNAFPWPSPDGKRIVFrsgrTGHKNLYIMD 533
Cdd:COG4946 272 --LDL--------------ASGEPRK--LNITL-AGDFPQRRPRWVDVSGYLTSFALSPDGKRVAF----EARGEVFTVP 328
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 534 AEKGE-------SGGLWRLTEgawtdtmcnWSPDGEWIAFASDRespgSGSFELFLIHPNGTGLRKLIQSGTGGRTNHPI 606
Cdd:COG4946 329 AEKGPtrnltntPGVRERLPA---------WSPDGKSIAYFSDA----SGEYELYIAPADGSGEPKQLTLGDLGRVFNPV 395
|
490 500 510 520 530 540
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 18395019 607 FSPDSKSLVFTSdyagisaepisnpHHyqpyGDIFTVKLDGSNVRRLTHNSY--EDGTPAWAP 667
Cdd:COG4946 396 WSPDGKKIAFTD-------------NR----GRLWVVDLASGKVRKVDTDGYgdGISDLAWSP 441
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
564-668 |
1.50e-14 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 71.63 E-value: 1.50e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 564 IAFASDREspgsGSFELFLIHPNGTGLRKLIQSGtgGRTNHPIFSPDSKSLVFTSDYAGISaepisnphhyqpygDIFTV 643
Cdd:COG0823 1 LAFTLSRD----GNSDIYVVDLDGGEPRRLTNSP--GIDTSPAWSPDGRRIAFTSDRGGGP--------------QIYVV 60
|
90 100
....*....|....*....|....*
gi 18395019 644 KLDGSNVRRLTHNSYEDGTPAWAPR 668
Cdd:COG0823 61 DADGGEPRRLTFGGGYNASPSWSPD 85
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
354-548 |
7.40e-12 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 63.92 E-value: 7.40e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 354 ELTRLVAPKSHHLNPFLSPDSSRVGYHSCRGDangrrSPLLFLENIQTTT-RDLSLFRIDGSFPSFSPGGDRIAYVKMPG 432
Cdd:COG0823 22 EPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGG-----GPQIYVVDADGGEpRRLTFGGGYNASPSWSPDGKRLAFVSRSD 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 433 ----VFVVKPDGSGqrevykgmafstawdpvrpgivysssgptfatertevdvisidvdaadksssVRRLTTNGKNNAFp 508
Cdd:COG0823 97 grfdIYVLDLDGGA----------------------------------------------------PRRLTDGPGSPSW- 123
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 18395019 509 wpSPDGKRIVFRSGRTGHKNLYIMDAekgeSGGLWRLTEG 548
Cdd:COG0823 124 --SPDGRRIVFSSDRGGRPDLYVVDL----DGRKRRLTPA 157
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
165-289 |
4.72e-08 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 52.75 E-value: 4.72e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 165 PSLS--GEFIVYVSThessgepRASWTAVYSTELKTGLTRRLTPSGVADFSPAVSPSGNLTAVASYGERGWtgeveelrt 242
Cdd:COG0823 36 PAWSpdGRRIAFTSD-------RGGGPQIYVVDADGGEPRRLTFGGGYNASPSWSPDGKRLAFVSRSDGRF--------- 99
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 18395019 243 DIYVfLTRDGSHRVKVVEHGGWPCW-VDESTLYFHRRSEEDGWISVYR 289
Cdd:COG0823 100 DIYV-LDLDGGAPRRLTDGPGSPSWsPDGRRIVFSSDRGGRPDLYVVD 146
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
242-410 |
2.66e-05 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 45.05 E-value: 2.66e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 242 TDIYVfLTRDGSHRVKVVEHGGW---PCW-VDESTLYFhrRSEEDGWISVYRailpengpLTTESVTIQRVTPPGVHAFT 317
Cdd:COG0823 11 SDIYV-VDLDGGEPRRLTNSPGIdtsPAWsPDGRRIAF--TSDRGGGPQIYV--------VDADGGEPRRLTFGGGYNAS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 318 PATSPNNhEFVAVATRRPGSdyRHVELFDLKRNEFIELTRlvapksHHLNPFLSPDSSRVGYHSCRGdanGRRSplLFLE 397
Cdd:COG0823 80 PSWSPDG-KRLAFVSRSDGR--FDIYVLDLDGGAPRRLTD------GPGSPSWSPDGRRIVFSSDRG---GRPD--LYVV 145
|
170
....*....|...
gi 18395019 398 NIQTTTRDLSLFR 410
Cdd:COG0823 146 DLDGRKRRLTPAS 158
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
357-599 |
3.94e-05 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 46.68 E-value: 3.94e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 357 RLVAPKSHHLNPFLSPDSSRVGYHScrgDANGrrSPLLFLENIQTTT-------RDLS-LFRIDGSfPSFSPGGDRIayv 428
Cdd:PRK01029 225 KILALQGNQLMPTFSPRKKLLAFIS---DRYG--NPDLFIQSFSLETgaigkprRLLNeAFGTQGN-PSFSPDGTRL--- 295
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 429 kmpgVFVVKPDGsgqrevykgmafstawdpvRPGIVysssgptfatertevdVISIDvdaaDKSSSVRRLTTNGKNNAFP 508
Cdd:PRK01029 296 ----VFVSNKDG-------------------RPRIY----------------IMQID----PEGQSPRLLTKKYRNSSCP 332
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 509 WPSPDGKRIVFRSGRTGHKNLYIMDAEKGESgglWRLTEGAWTDTMCNWSPDGEWIAFASDrespGSGSFELFLIHPNGT 588
Cdd:PRK01029 333 AWSPDGKKIAFCSVIKGVRQICVYDLATGRD---YQLTTSPENKESPSWAIDSLHLVYSAG----NSNESELYLISLITK 405
|
250
....*....|.
gi 18395019 589 GLRKlIQSGTG 599
Cdd:PRK01029 406 KTRK-IVIGSG 415
|
|
| tolB |
PRK04043 |
Tol-Pal system protein TolB; |
418-519 |
4.09e-05 |
|
Tol-Pal system protein TolB;
Pssm-ID: 235212 [Multi-domain] Cd Length: 419 Bit Score: 46.53 E-value: 4.09e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 418 FSPGGDRIAYVK----MPGVFVVKPDGSG-QREVYKGMAFSTAwDPVRPGIVYSS--SGPTFATERTEVDVISIdvdaad 490
Cdd:PRK04043 284 FVEDDKRIVFVSdrlgYPNIFMKKLNSGSvEQVVFHGKNNSSV-STYKNYIVYSSreTNNEFGKNTFNLYLIST------ 356
|
90 100
....*....|....*....|....*....
gi 18395019 491 KSSSVRRLTTNGKNNaFPWPSPDGKRIVF 519
Cdd:PRK04043 357 NSDYIRRLTANGVNQ-FPRFSSDGGSIMF 384
|
|
| PD40 |
pfam07676 |
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. ... |
495-531 |
6.01e-05 |
|
WD40-like Beta Propeller Repeat; This family appears to be related to the pfam00400 repeat. This repeat corresponds to the RIVW repeat identified in cell surface proteins [Adindla et al. Comparative and Functional Genomics 2004; 5:2-16].
Pssm-ID: 429587 [Multi-domain] Cd Length: 37 Bit Score: 40.58 E-value: 6.01e-05
10 20 30
....*....|....*....|....*....|....*..
gi 18395019 495 VRRLTTNGKNNAFPWPSPDGKRIVFRSGRTGHKNLYI 531
Cdd:pfam07676 1 LGRLTNTPGNETAPSWSPDGKRLAFSSDRDGKPDIYV 37
|
|
| tolB |
PRK04043 |
Tol-Pal system protein TolB; |
513-625 |
1.45e-04 |
|
Tol-Pal system protein TolB;
Pssm-ID: 235212 [Multi-domain] Cd Length: 419 Bit Score: 44.98 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 513 DGKRIVFRSGRTGHKNLYIMDAEkgeSGGLWRLTEGAWTDTMCnwSPDGEWIAFASdRESP---GSGSFELFLIHPNGTG 589
Cdd:PRK04043 287 DDKRIVFVSDRLGYPNIFMKKLN---SGSVEQVVFHGKNNSSV--STYKNYIVYSS-RETNnefGKNTFNLYLISTNSDY 360
|
90 100 110
....*....|....*....|....*....|....*.
gi 18395019 590 LRKLIqsgTGGRTNHPIFSPDSKSLVFTSDYAGISA 625
Cdd:PRK04043 361 IRRLT---ANGVNQFPRFSSDGGSIMFIKYLGNQSA 393
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
511-669 |
4.35e-04 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 43.21 E-value: 4.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 511 SPDGKRIVFRSGRTGHKNLYIMD-AEKGESGGLwrLTEGAWTDTMCNWSPDGEWIAFASDREspgsgSFELFLIHPNGTG 589
Cdd:PRK01029 289 SPDGTRLVFVSNKDGRPRIYIMQiDPEGQSPRL--LTKKYRNSSCPAWSPDGKKIAFCSVIK-----GVRQICVYDLATG 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 590 LRKLIQSGTGGRTNhPIFSPDSKSLVFTSDYAGISaepisnphhyqpygDIFTVKLDGSNVRRLTHNSYEDGTPAWAPRF 669
Cdd:PRK01029 362 RDYQLTTSPENKES-PSWAIDSLHLVYSAGNSNES--------------ELYLISLITKKTRKIVIGSGEKRFPSWGAFP 426
|
|
| TolB |
COG0823 |
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ... |
172-337 |
9.37e-04 |
|
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 440585 [Multi-domain] Cd Length: 158 Bit Score: 40.43 E-value: 9.37e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 172 IVYVSTHESSGEpraswtaVYSTELKTGLTRRLTPSGVADFSPAVSPSGNLTAVASYGERGWtgeveelrtDIYVfLTRD 251
Cdd:COG0823 1 LAFTLSRDGNSD-------IYVVDLDGGEPRRLTNSPGIDTSPAWSPDGRRIAFTSDRGGGP---------QIYV-VDAD 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 252 GSHRVKVVEHGGW---PCWV-DESTLYFhrRSEEDGWISVYRailpengpLTTESVTIQRVTPPgvhAFTPATSPNNhEF 327
Cdd:COG0823 64 GGEPRRLTFGGGYnasPSWSpDGKRLAF--VSRSDGRFDIYV--------LDLDGGAPRRLTDG---PGSPSWSPDG-RR 129
|
170
....*....|
gi 18395019 328 VAVATRRPGS 337
Cdd:COG0823 130 IVFSSDRGGR 139
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
459-671 |
1.20e-03 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 42.06 E-value: 1.20e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 459 VRPGIVYSSSGPTFATERTEVDVISIDVDAADKSSSVRRLTTNGkNNAFPWPSPDGKRIVFRSGRTGHKNLYI--MDAEK 536
Cdd:PRK01029 188 ITPTWMHIGSGFPYLYVSYKLGVPKIFLGSLENPAGKKILALQG-NQLMPTFSPRKKLLAFISDRYGNPDLFIqsFSLET 266
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 537 GESGGLWR-LTEGAWTDTMCNWSPDGEWIAFASDREspGSGSFELFLIHPNGTGLRKLIQSGtggRTNH-PIFSPDSKSL 614
Cdd:PRK01029 267 GAIGKPRRlLNEAFGTQGNPSFSPDGTRLVFVSNKD--GRPRIYIMQIDPEGQSPRLLTKKY---RNSScPAWSPDGKKI 341
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 18395019 615 VFTSDYAGISaepisnphhyqpygDIFTVKLDGSNVRRLTHNSYEDGTPAWAPRFIH 671
Cdd:PRK01029 342 AFCSVIKGVR--------------QICVYDLATGRDYQLTTSPENKESPSWAIDSLH 384
|
|
| tolB |
PRK01029 |
Tol-Pal system protein TolB; |
463-667 |
2.10e-03 |
|
Tol-Pal system protein TolB;
Pssm-ID: 234889 [Multi-domain] Cd Length: 428 Bit Score: 41.29 E-value: 2.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 463 IVYSSSGPTFATERTEVDVISIDVDAADksssVRRLTTNGKNNAFP-W-PSPDGKRIVFRSGRTGHKNLYIMDAEKGESG 540
Cdd:PRK01029 149 IIFSLSTTNSDTELKQGELWSVDYDGQN----LRPLTQEHSLSITPtWmHIGSGFPYLYVSYKLGVPKIFLGSLENPAGK 224
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18395019 541 GLWRLTEGAWtdtMCNWSPDGEWIAFASDRespgSGSFELFL----IHPNGTGLRKLIQSGTGGRTNHPIFSPDSKSLVF 616
Cdd:PRK01029 225 KILALQGNQL---MPTFSPRKKLLAFISDR----YGNPDLFIqsfsLETGAIGKPRRLLNEAFGTQGNPSFSPDGTRLVF 297
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 18395019 617 TSDYAGisaepisNPHHYqpygdIFTVKLDGSNVRRLTHNSYEDGTPAWAP 667
Cdd:PRK01029 298 VSNKDG-------RPRIY-----IMQIDPEGQSPRLLTKKYRNSSCPAWSP 336
|
|
| |
