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Conserved domains on  [gi|18407407|ref|NP_566106|]
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alpha/beta-Hydrolases superfamily protein [Arabidopsis thaliana]

Protein Classification

alpha/beta hydrolase family protein( domain architecture ID 229394)

alpha/beta hydrolase family protein may catalyze the hydrolysis of substrates with different chemical composition or physicochemical properties using a nucleophile-His-acid catalytic triad

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Abhydrolase super family cl21494
alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, ...
 10-293 7.55e-119

alpha/beta hydrolases; A functionally diverse superfamily containing proteases, lipases, peroxidases, esterases, epoxide hydrolases and dehalogenases. The catalytic apparatus typically involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine, and often the mechanism involves a nucleophilic attack on a carbonyl carbon atom.


The actual alignment was detected with superfamily member PLN02385:

Pssm-ID: 473884 [Multi-domain]  Cd Length: 349  Bit Score: 347.12  E-value: 7.55e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   10 EEYVRNSRGVELFACRWIPSSSSsPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFAN 89
Cdd:PLN02385  63 ESYEVNSRGVEIFSKSWLPENSR-PKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   90 VVNDCYDYYTSICAQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKVKPHPIVINLLTRVEEIIP 169
Cdd:PLN02385 142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  170 KWKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKAL 249
Cdd:PLN02385 222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 18407407  250 YEKASTRDKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLDLR 293
Cdd:PLN02385 302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
 
Name Accession Description Interval E-value
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 10-293 7.55e-119

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 347.12  E-value: 7.55e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   10 EEYVRNSRGVELFACRWIPSSSSsPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFAN 89
Cdd:PLN02385  63 ESYEVNSRGVEIFSKSWLPENSR-PKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   90 VVNDCYDYYTSICAQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKVKPHPIVINLLTRVEEIIP 169
Cdd:PLN02385 142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  170 KWKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKAL 249
Cdd:PLN02385 222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 18407407  250 YEKASTRDKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLDLR 293
Cdd:PLN02385 302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 32-276 5.08e-67

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 210.92  E-value: 5.08e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    32 SSPKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVVNDCYDYYTSICAQEEYMDkg 111
Cdd:pfam12146   1 GEPRAVVVLVHGLG-EHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLP-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   112 RFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKvKPHPIVINLLTRVEEIIPKWKiVPTKDVIDAAFKDLVKRE 191
Cdd:pfam12146  78 LFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPY-LAPPILKLLAKLLGKLFPRLR-VPNNLLPDSLSRDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   192 EVRNNKLIyQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYEKASTRDKTLKLYPGMWHALT 271
Cdd:pfam12146 156 AYAADPLV-HGGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234


                  ....*
gi 18407407   272 sGEPD 276
Cdd:pfam12146 235 -NEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
9-291 7.19e-36

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 129.74  E-value: 7.19e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   9 HEEYVRNSRGVELFACRWIPSSSssPKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFA 88
Cdd:COG2267   4 RLVTLPTRDGLRLRGRRWRPAGS--PRGTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  89 NVVNDCYDYYTSICAQEeymDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMckisekvkphpivinlltrveeii 168
Cdd:COG2267  81 DYVDDLRAALDALRARP---GLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPA------------------------ 133

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 169 pkwkivptkdvidaafkdlvkreevrnnkliYQDKPRLKTALEMLRtSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKA 248
Cdd:COG2267 134 -------------------------------YRADPLLGPSARWLR-ALRLAEALARIDVPVLVLHGGADRVVPPEAARR 181

                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 18407407 249 LYEKAStRDKTLKLYPGMWHALTSgepDCNVDLVFADIINWLD 291
Cdd:COG2267 182 LAARLS-PDVELVLLPGARHELLN---EPAREEVLAAILAWLE 220
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 58-271 1.06e-09

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 59.02  E-value: 1.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    58 RLASAGYAVFGMDYEGHGRSMGS---RCYIKKFANVVNDCYDYY-----TSICAQEEYMD----------KGR---FLYG 116
Cdd:TIGR01607  69 NFNKNGYSVYGLDLQGHGESDGLqnlRGHINCFDDLVYDVIQYMnrindSIILENETKSDdesydivntkENRlpmYIIG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   117 ESMGGAVTL----LLHKKDPLFWN----GAILVAPMCKISEKVKPHPI--------VINLLTRveeIIPKWKIVPTKDVI 180
Cdd:TIGR01607 149 LSMGGNIALrlleLLGKSNENNDKlnikGCISLSGMISIKSVGSDDSFkfkyfylpVMNFMSR---VFPTFRISKKIRYE 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   181 DAAF-KDLVKREEVRNNKLIyqdkpRLKTALEMLRTSMNLEDTLHEI--TMPFFVLHGEADTVTDPEVSKALYEKASTRD 257
Cdd:TIGR01607 226 KSPYvNDIIKFDKFRYDGGI-----TFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISN 300

                         250
                  ....*....|....
gi 18407407   258 KTLKLYPGMWHALT 271
Cdd:TIGR01607 301 KELHTLEDMDHVIT 314
 
Name Accession Description Interval E-value
PLN02385 PLN02385
hydrolase; alpha/beta fold family protein
 10-293 7.55e-119

hydrolase; alpha/beta fold family protein


Pssm-ID: 215216 [Multi-domain]  Cd Length: 349  Bit Score: 347.12  E-value: 7.55e-119
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   10 EEYVRNSRGVELFACRWIPSSSSsPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFAN 89
Cdd:PLN02385  63 ESYEVNSRGVEIFSKSWLPENSR-PKAAVCFCHGYGDTCTFFFEGIARKIASSGYGVFAMDYPGFGLSEGLHGYIPSFDD 141

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   90 VVNDCYDYYTSICAQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKVKPHPIVINLLTRVEEIIP 169
Cdd:PLN02385 142 LVDDVIEHYSKIKGNPEFRGLPSFLFGQSMGGAVALKVHLKQPNAWDGAILVAPMCKIADDVVPPPLVLQILILLANLLP 221

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  170 KWKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKAL 249
Cdd:PLN02385 222 KAKLVPQKDLAELAFRDLKKRKMAEYNVIAYKDKPRLRTAVELLRTTQEIEMQLEEVSLPLLILHGEADKVTDPSVSKFL 301

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 18407407  250 YEKASTRDKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLDLR 293
Cdd:PLN02385 302 YEKASSSDKKLKLYEDAYHSILEGEPDEMIFQVLDDIISWLDSH 345
PLN02298 PLN02298
hydrolase, alpha/beta fold family protein
 11-298 1.60e-108

hydrolase, alpha/beta fold family protein


Pssm-ID: 165939 [Multi-domain]  Cd Length: 330  Bit Score: 320.19  E-value: 1.60e-108
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   11 EYVRNSRGVELFACRWIPSSSSSPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANV 90
Cdd:PLN02298  35 SFFTSPRGLSLFTRSWLPSSSSPPRALIFMVHGYGNDISWTFQSTAIFLAQMGFACFALDLEGHGRSEGLRAYVPNVDLV 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   91 VNDCYDYYTSICAQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKVKPHPIVINLLTRVEEIIPK 170
Cdd:PLN02298 115 VEDCLSFFNSVKQREEFQGLPRFLYGESMGGAICLLIHLANPEGFDGAVLVAPMCKISDKIRPPWPIPQILTFVARFLPT 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  171 WKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALY 250
Cdd:PLN02298 195 LAIVPTADLLEKSVKVPAKKIIAKRNPMRYNGKPRLGTVVELLRVTDYLGKKLKDVSIPFIVLHGSADVVTDPDVSRALY 274

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*...
gi 18407407  251 EKASTRDKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLDLRTADPA 298
Cdd:PLN02298 275 EEAKSEDKTIKIYDGMMHSLLFGEPDENIEIVRRDILSWLNERCTGKA 322
Hydrolase_4 pfam12146
Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is ...
 32-276 5.08e-67

Serine aminopeptidase, S33; This domain is found in bacteria and eukaryotes and is approximately 110 amino acids in length. It is found in association with pfam00561. The majority of the members in this family carry the exopeptidase active-site residues of Ser-122, Asp-239 and His-269 as in UniProtKB:Q7ZWC2.


Pssm-ID: 463473 [Multi-domain]  Cd Length: 238  Bit Score: 210.92  E-value: 5.08e-67
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    32 SSPKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVVNDCYDYYTSICAQEEYMDkg 111
Cdd:pfam12146   1 GEPRAVVVLVHGLG-EHSGRYAHLADALAAQGFAVYAYDHRGHGRSDGKRGHVPSFDDYVDDLDTFVDKIREEHPGLP-- 77

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   112 RFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKISEKvKPHPIVINLLTRVEEIIPKWKiVPTKDVIDAAFKDLVKRE 191
Cdd:pfam12146  78 LFLLGHSMGGLIAALYALRYPDKVDGLILSAPALKIKPY-LAPPILKLLAKLLGKLFPRLR-VPNNLLPDSLSRDPEVVA 155

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   192 EVRNNKLIyQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYEKASTRDKTLKLYPGMWHALT 271
Cdd:pfam12146 156 AYAADPLV-HGGISARTLYELLDAGERLLRRAAAITVPLLLLHGGADRVVDPAGSREFYERAGSTDKTLKLYPGLYHELL 234


                  ....*
gi 18407407   272 sGEPD 276
Cdd:pfam12146 235 -NEPD 238
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
9-291 7.19e-36

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 129.74  E-value: 7.19e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   9 HEEYVRNSRGVELFACRWIPSSSssPKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFA 88
Cdd:COG2267   4 RLVTLPTRDGLRLRGRRWRPAGS--PRGTVVLVHGLG-EHSGRYAELAEALAAAGYAVLAFDLRGHGRSDGPRGHVDSFD 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  89 NVVNDCYDYYTSICAQEeymDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMckisekvkphpivinlltrveeii 168
Cdd:COG2267  81 DYVDDLRAALDALRARP---GLPVVLLGHSMGGLIALLYAARYPDRVAGLVLLAPA------------------------ 133

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 169 pkwkivptkdvidaafkdlvkreevrnnkliYQDKPRLKTALEMLRtSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKA 248
Cdd:COG2267 134 -------------------------------YRADPLLGPSARWLR-ALRLAEALARIDVPVLVLHGGADRVVPPEAARR 181

                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 18407407 249 LYEKAStRDKTLKLYPGMWHALTSgepDCNVDLVFADIINWLD 291
Cdd:COG2267 182 LAARLS-PDVELVLLPGARHELLN---EPAREEVLAAILAWLE 220
PLN02652 PLN02652
hydrolase; alpha/beta fold family protein
 13-296 2.09e-30

hydrolase; alpha/beta fold family protein


Pssm-ID: 215352 [Multi-domain]  Cd Length: 395  Bit Score: 119.23  E-value: 2.09e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   13 VRNSRGVELFACRWIPSSSSSpKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVVN 92
Cdd:PLN02652 115 FYGARRNALFCRSWAPAAGEM-RGILIIIHGLN-EHSGRYLHFAKQLTSCGFGVYAMDWIGHGGSDGLHGYVPSLDYVVE 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   93 DCydyytsicaqEEYMDKGR--------FLYGESMGGAVTL----LLHKKDPLfwNGAILVAPmckiSEKVKP-HPIVIN 159
Cdd:PLN02652 193 DT----------EAFLEKIRsenpgvpcFLFGHSTGGAVVLkaasYPSIEDKL--EGIVLTSP----ALRVKPaHPIVGA 256

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  160 LLTRVEEIIPKWKIVPTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADT 239
Cdd:PLN02652 257 VAPIFSLVAPRFQFKGANKRGIPVSRDPAALLAKYSDPLVYTGPIRVRTGHEILRISSYLTRNFKSVTVPFMVLHGTADR 336

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 18407407  240 VTDPEVSKALYEKASTRDKTLKLYPGMWHALTSgEPDcnVDLVFADIINWLDLRTAD 296
Cdd:PLN02652 337 VTDPLASQDLYNEAASRHKDIKLYDGFLHDLLF-EPE--REEVGRDIIDWMEKRLDL 390
YvaK COG1647
Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];
38-291 7.43e-29

Esterase/lipase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 441253 [Multi-domain]  Cd Length: 246  Bit Score: 111.96  E-value: 7.43e-29
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  38 VFLCHGYgMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSrcyikkFANV-VNDCYDyytsiCAQEEYmDKGR---- 112
Cdd:COG1647  18 VLLLHGF-TGSPAEMRPLAEALAKAGYTVYAPRLPGHGTSPED------LLKTtWEDWLE-----DVEEAY-EILKagyd 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 113 --FLYGESMGGAVTLLLHKKDPLFwNGAILVAPMCKISEkvkPHPIVINLLTRVEEIIPKWKIVPtkdvidaafkdlvkr 190
Cdd:COG1647  85 kvIVIGLSMGGLLALLLAARYPDV-AGLVLLSPALKIDD---PSAPLLPLLKYLARSLRGIGSDI--------------- 145

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 191 EEVRNNKLIYQDKPrLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYEKASTRDKTLKLYPGMWHAL 270
Cdd:COG1647 146 EDPEVAEYAYDRTP-LRALAELQRLIREVRRDLPKITAPTLIIQSRKDEVVPPESARYIYERLGSPDKELVWLEDSGHVI 224

                       250       260
                ....*....|....*....|.
gi 18407407 271 TSgepDCNVDLVFADIINWLD 291
Cdd:COG1647 225 TL---DKDREEVAEEILDFLE 242
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
13-291 8.67e-24

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 97.78  E-value: 8.67e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  13 VRNSRGVELFAcRWIPSSSSSPKALVFLCHGYGMECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSrcYIKKFANVVN 92
Cdd:COG1506   2 FKSADGTTLPG-WLYLPADGKKYPVVVYVHGGPGSRDDSFLPLAQALASRGYAVLAPDYRGYGESAGD--WGGDEVDDVL 78

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  93 DCYDYYtsicAQEEYMDKGR-FLYGESMGGAVTLLLHKKDPLFWNGAILVAPmckisekvkphpiVINLLTRVEEIipkw 171
Cdd:COG1506  79 AAIDYL----AARPYVDPDRiGIYGHSYGGYMALLAAARHPDRFKAAVALAG-------------VSDLRSYYGTT---- 137

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 172 kivptkdvidaafkdlvkREEVRNNKLIYQDKPrlktalEMLRTsMNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYE 251
Cdd:COG1506 138 ------------------REYTERLMGGPWEDP------EAYAA-RSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYE 192

                       250       260       270       280
                ....*....|....*....|....*....|....*....|...
gi 18407407 252 KASTR--DKTLKLYPGMWHALT-SGEPDcnvdlVFADIINWLD 291
Cdd:COG1506 193 ALKKAgkPVELLVYPGEGHGFSgAGAPD-----YLERILDFLD 230
PHA02857 PHA02857
monoglyceride lipase; Provisional
 12-290 7.94e-23

monoglyceride lipase; Provisional


Pssm-ID: 165193 [Multi-domain]  Cd Length: 276  Bit Score: 96.11  E-value: 7.94e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   12 YVRNSRGVELFACRWIPSSSssPKALVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVV 91
Cdd:PHA02857   4 CMFNLDNDYIYCKYWKPITY--PKALVFISHGAG-EHSGRYEELAENISSLGILVFSHDHIGHGRSNGEKMMIDDFGVYV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   92 NDCYDYYTSIcaQEEYMDKGRFLYGESMGGAVTLLLHKKDPLFWNGAILVAPMCKiSEKVkphPIVINLLTRVEEIIPKW 171
Cdd:PHA02857  81 RDVVQHVVTI--KSTYPGVPVFLLGHSMGATISILAAYKNPNLFTAMILMSPLVN-AEAV---PRLNLLAAKLMGIFYPN 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  172 KIVpTKDVIDAAFKDLVKREEVRNNKLIYQDKPRLKTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDpeVSKALY- 250
Cdd:PHA02857 155 KIV-GKLCPESVSRDMDEVYKYQYDPLVNHEKIKAGFASQVLKATNKVRKIIPKIKTPILILQGTNNEISD--VSGAYYf 231

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|
gi 18407407  251 EKASTRDKTLKLYPGMWHALTSgEPDCNVDLVFADIINWL 290
Cdd:PHA02857 232 MQHANCNREIKIYEGAKHHLHK-ETDEVKKSVMKEIETWI 270
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 13-291 9.23e-23

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 95.37  E-value: 9.23e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  13 VRNSRGVELFACRWIPSSSSSPKALVFLCHGYGMECSDSMKEcGIRLASAGYAVFGMDYEGHGRSMGS-RCYIKKFANVV 91
Cdd:COG1073  15 FKSRDGIKLAGDLYLPAGASKKYPAVVVAHGNGGVKEQRALY-AQRLAELGFNVLAFDYRGYGESEGEpREEGSPERRDA 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  92 NDCYDYytsiCAQEEYMDKGR-FLYGESMGGAVTLLLHKKDPLFwNGAILVAPMckisekvkphpivinlltrveeiipk 170
Cdd:COG1073  94 RAAVDY----LRTLPGVDPERiGLLGISLGGGYALNAAATDPRV-KAVILDSPF-------------------------- 142

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 171 wkivptkDVIDAAFKDLVKREEVRNNKLI-YqdKPRLkTALEMLRTSMNLEDTLHEITMPFFVLHGEADTVTDPEVSKAL 249
Cdd:COG1073 143 -------TSLEDLAAQRAKEARGAYLPGVpY--LPNV-RLASLLNDEFDPLAKIEKISRPLLFIHGEKDEAVPFYMSEDL 212

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 18407407 250 YEKASTrDKTLKLYPGMWHALTSGEPDcnvDLVFADIINWLD 291
Cdd:COG1073 213 YEAAAE-PKELLIVPGAGHVDLYDRPE---EEYFDKLAEFFK 250
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 35-291 2.51e-11

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 62.71  E-value: 2.51e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  35 KALVFLcHGYGMeCSDSMKECgIRLASAGYAVFGMDYEGHGRSMGSRcyikkfanvvnDCYDYYTSICAQEEYMDK---G 111
Cdd:COG0596  24 PPVVLL-HGLPG-SSYEWRPL-IPALAAGYRVIAPDLRGHGRSDKPA-----------GGYTLDDLADDLAALLDAlglE 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 112 RF-LYGESMGGAVTLLLhkkdplfwngAILvapmckisekvkpHPivinllTRVEEIIpkwkivptkdVIDAAFKDLVKR 190
Cdd:COG0596  90 RVvLVGHSMGGMVALEL----------AAR-------------HP------ERVAGLV----------LVDEVLAALAEP 130

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 191 EEVRNnkliyQDKPRLKTALEMLRTSmNLEDTLHEITMPFFVLHGEADTVTDPEVSKALYEKAstRDKTLKLYPGMWHAL 270
Cdd:COG0596 131 LRRPG-----LAPEALAALLRALART-DLRERLARITVPTLVIWGEKDPIVPPALARRLAELL--PNAELVVLPGAGHFP 202

                       250       260
                ....*....|....*....|.
gi 18407407 271 TSGEPdcnvDLVFADIINWLD 291
Cdd:COG0596 203 PLEQP----EAFAAALRDFLA 219
PST-A TIGR01607
Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in ...
 58-271 1.06e-09

Plasmodium subtelomeric family (PST-A); This model represents a paralogous family of genes in Plasmodium falciparum and Plasmodium yoelii, which are closely related to various phospholipases and lysophospholipases of plants as well as generally being related to the alpha/beta-fold superfamily of hydrolases. These genes are preferentially located in the subtelomeric regions of the chromosomes of both P. falciparum and P. yoelii.


Pssm-ID: 162444 [Multi-domain]  Cd Length: 332  Bit Score: 59.02  E-value: 1.06e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    58 RLASAGYAVFGMDYEGHGRSMGS---RCYIKKFANVVNDCYDYY-----TSICAQEEYMD----------KGR---FLYG 116
Cdd:TIGR01607  69 NFNKNGYSVYGLDLQGHGESDGLqnlRGHINCFDDLVYDVIQYMnrindSIILENETKSDdesydivntkENRlpmYIIG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   117 ESMGGAVTL----LLHKKDPLFWN----GAILVAPMCKISEKVKPHPI--------VINLLTRveeIIPKWKIVPTKDVI 180
Cdd:TIGR01607 149 LSMGGNIALrlleLLGKSNENNDKlnikGCISLSGMISIKSVGSDDSFkfkyfylpVMNFMSR---VFPTFRISKKIRYE 225

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   181 DAAF-KDLVKREEVRNNKLIyqdkpRLKTALEMLRTSMNLEDTLHEI--TMPFFVLHGEADTVTDPEVSKALYEKASTRD 257
Cdd:TIGR01607 226 KSPYvNDIIKFDKFRYDGGI-----TFNLASELIKATDTLDCDIDYIpkDIPILFIHSKGDCVCSYEGTVSFYNKLSISN 300

                         250
                  ....*....|....
gi 18407407   258 KTLKLYPGMWHALT 271
Cdd:TIGR01607 301 KELHTLEDMDHVIT 314
PRK10749 PRK10749
lysophospholipase L2; Provisional
 63-242 8.91e-08

lysophospholipase L2; Provisional


Pssm-ID: 182697  Cd Length: 330  Bit Score: 53.08  E-value: 8.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   63 GYAVFGMDYEGHGRSM-----GSRCYIKKFANVVNDCYDYYTSICAQEEYmdKGRFLYGESMGGAVTLLLHKKDPLFWNG 137
Cdd:PRK10749  81 GYDVLIIDHRGQGRSGrllddPHRGHVERFNDYVDDLAAFWQQEIQPGPY--RKRYALAHSMGGAILTLFLQRHPGVFDA 158

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  138 AILVAPMCKI-----------------------------SEKVKPHPIVINLLTRveeiipkwkivptkdvidaafkdlv 188
Cdd:PRK10749 159 IALCAPMFGIvlplpswmarrilnwaeghprirdgyaigTGRWRPLPFAINVLTH------------------------- 213

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18407407  189 KREEVRNNKLIYQDKPRLKTA---LEMLRTSMNLEDTL----HEITMPFFVLHGEADTVTD 242
Cdd:PRK10749 214 SRERYRRNLRFYADDPELRVGgptYHWVRESILAGEQVlagaGDITTPLLLLQAEEERVVD 274
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
18-291 1.98e-05

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 45.34  E-value: 1.98e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  18 GVELFACRWIPSSSSsPKALVFLCHG-YGMecSDSMKECGIRLASAGYAVFGMD---------YEGHGRSMGSRCYIKKF 87
Cdd:COG0412  13 GVTLPGYLARPAGGG-PRPGVVVLHEiFGL--NPHIRDVARRLAAAGYVVLAPDlygrggpgdDPDEARALMGALDPELL 89

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  88 ANVVNDCYDYytsiCAQEEYMDKGRF-LYGESMGGAVTLLLHKKDPLFwNGAILVAPMCkisekvkphpivinlltrvee 166
Cdd:COG0412  90 AADLRAALDW----LKAQPEVDAGRVgVVGFCFGGGLALLAAARGPDL-AAAVSFYGGL--------------------- 143

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 167 iipkwkivptkdvIDAAFKDLVKReevrnnkliyqdkprlktalemlrtsmnledtlheITMPFFVLHGEADTVTDPEVS 246
Cdd:COG0412 144 -------------PADDLLDLAAR-----------------------------------IKAPVLLLYGEKDPLVPPEQV 175

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|.
gi 18407407 247 KALYE--KASTRDKTLKLYPGMWHALTS-GEPDCN---VDLVFADIINWLD 291
Cdd:COG0412 176 AALEAalAAAGVDVELHVYPGAGHGFTNpGRPRYDpaaAEDAWQRTLAFLA 226
Abhydrolase_6 pfam12697
Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse ...
 38-276 1.47e-04

Alpha/beta hydrolase family; This family contains alpha/beta hydrolase enzymes of diverse specificity.


Pssm-ID: 463673 [Multi-domain]  Cd Length: 211  Bit Score: 42.46  E-value: 1.47e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    38 VFLCHGYGMeCSDSMkecgIRLASAGYAVFGMDYEGHGRSMGSRCYIKKFANVVNDcydyytsicAQEEYMDKGRFLYGE 117
Cdd:pfam12697   1 VVLVHGAGL-SAAPL----AALLAAGVAVLAPDLPGHGSSSPPPLDLADLADLAAL---------LDELGAARPVVLVGH 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407   118 SMGGAVTLLLHKKDPLFwngAILVAPMckiSEKVKPHPIVINLLTRVEEIIPKWKIVPTKDVIDAAFKDLVKREEVRNNk 197
Cdd:pfam12697  67 SLGGAVALAAAAAALVV---GVLVAPL---AAPPGLLAALLALLARLGAALAAPAWLAAESLARGFLDDLPADAEWAAA- 139

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18407407   198 liYQDKPRLKTALEMLRTsmnleDTLHEITMPFFVLHGEaDTVTDPEVSKALyekASTRDKTLKLYPGMWHALTSgEPD 276
Cdd:pfam12697 140 --LARLAALLAALALLPL-----AAWRDLPVPVLVLAEE-DRLVPELAQRLL---AALAGARLVVLPGAGHLPLD-DPE 206
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
26-291 3.06e-04

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 41.40  E-value: 3.06e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  26 WIPSSSSSPKALVFLCHG--YGMECSDSMKECGIRLAS-AGYAVFGMDY----EGhgrsmgsrcyikKFANVVNDCYDYY 98
Cdd:COG0657   4 YRPAGAKGPLPVVVYFHGggWVSGSKDTHDPLARRLAArAGAAVVSVDYrlapEH------------PFPAALEDAYAAL 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  99 TSICAQ-EEY-MDKGR-FLYGESMGG--AVTLLLHKKDPLFW--NGAILVAPMckisekvkphpivINLLtrveeiipkw 171
Cdd:COG0657  72 RWLRANaAELgIDPDRiAVAGDSAGGhlAAALALRARDRGGPrpAAQVLIYPV-------------LDLT---------- 128

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407 172 kIVPtkdvIDAAFKDLvkreevrnnkliyqdkPrlktalemlrtsmnledtlheitmPFFVLHGEADTVTDPevSKALYE 251
Cdd:COG0657 129 -ASP----LRADLAGL----------------P------------------------PTLIVTGEADPLVDE--SEALAA 161

                       250       260       270       280
                ....*....|....*....|....*....|....*....|..
gi 18407407 252 KASTR--DKTLKLYPGMWHALTSGEPDCNVDLVFADIINWLD 291
Cdd:COG0657 162 ALRAAgvPVELHVYPGGGHGFGLLAGLPEARAALAEIAAFLR 203
Abhydrolase_1 pfam00561
alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.
 37-144 7.93e-04

alpha/beta hydrolase fold; This catalytic domain is found in a very wide range of enzymes.


Pssm-ID: 395444 [Multi-domain]  Cd Length: 245  Bit Score: 40.57  E-value: 7.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407    37 LVFLCHGYGmECSDSMKECGIRLASAGYAVFGMDYEGHGRSMGSRCyikkfanvvndCYDYYT-SICAQ----EEYMDKG 111
Cdd:pfam00561   2 PVLLLHGLP-GSSDLWRKLAPALARDGFRVIALDLRGFGKSSRPKA-----------QDDYRTdDLAEDleyiLEALGLE 69

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 18407407   112 RF-LYGESMGGAV--TLLLHKKDPLfwNGAILVAPM 144
Cdd:pfam00561  70 KVnLVGHSMGGLIalAYAAKYPDRV--KALVLLGAL 103
Axe1 COG3458
Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, ...
 38-126 1.78e-03

Cephalosporin-C deacetylase or related acetyl esterase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442681 [Multi-domain]  Cd Length: 318  Bit Score: 39.79  E-value: 1.78e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  38 VFLCHGYGMEcSDSMKEcGIRLASAGYAVFGMDYEGHGRSMGS------------------------RCYIKkfaNVVND 93
Cdd:COG3458  85 VVEFHGYGGG-RGLPHE-DLDWAAAGYAVLVMDTRGQGSSWGDtpdpggysggalpgymtrgiddpdTYYYR---RVYLD 159

                        90       100       110
                ....*....|....*....|....*....|....*..
gi 18407407  94 CY---DYytsICAQEEYmDKGR-FLYGESMGGAVTLL 126
Cdd:COG3458 160 AVravDA---LRSLPEV-DGKRiGVTGGSQGGGLALA 192
PhaC COG3243
Poly-beta-hydroxybutyrate synthase [Lipid transport and metabolism];
194-265 2.02e-03

Poly-beta-hydroxybutyrate synthase [Lipid transport and metabolism];


Pssm-ID: 442475 [Multi-domain]  Cd Length: 545  Bit Score: 39.94  E-value: 2.02e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 18407407 194 RNNKLIyqdkprlKTALEMLRTSMNLEDtlheITMPFFVLHGEADTVTDPEVSKALYEKASTRDKTLKLYPG 265
Cdd:COG3243 407 LENRLA-------KGELELGGRPVDLSD----ITVPVLVVAGEEDHIAPWRSVYALAQLVGGKDVTFVLAPG 467
YheT COG0429
Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];
33-125 4.87e-03

Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only];


Pssm-ID: 440198 [Multi-domain]  Cd Length: 323  Bit Score: 38.20  E-value: 4.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18407407  33 SPKALVFLCHGygME-CSDS--MKECGIRLASAGYAVFGMDYEGHGRSMG--SRCY----IKKFANVVNDcydyytsicA 103
Cdd:COG0429  59 PSKPLVVLLHG--LEgSSDShyARGLARALYARGWDVVRLNFRGCGGEPNllPRLYhsgdTEDLVWVLAH---------L 127

                        90       100
                ....*....|....*....|..
gi 18407407 104 QEEYMDKGRFLYGESMGGAVTL 125
Cdd:COG0429 128 RARYPYAPLYAVGFSLGGNLLL 149
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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