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Conserved domains on  [gi|18398038|ref|NP_566316|]
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Galactose oxidase/kelch repeat superfamily protein [Arabidopsis thaliana]

Protein Classification

Kelch domain-containing protein( domain architecture ID 1002449)

Kelch domain-containing protein is a protein that contains one or more kelch domains which play a role in a variety of cellular processes, including cell signaling, transcription regulation, and protein degradation.

Gene Ontology:  GO:0016567|GO:0080028
PubMed:  31442578|24959344

Graphical summary

 Zoom to residue level

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List of domain hits

 Name Accession Description Interval E-value
PLN02193 super family cl31837
nitrile-specifier protein
 1-322 5.10e-136

nitrile-specifier protein


The actual alignment was detected with superfamily member PLN02193:

Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 394.32  E-value: 5.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038    1 MAATP-MEGKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLETQTWSIQEASGDAPPPR-VGV 78
Cdd:PLN02193 143 LPSTPkLLGKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDKHLYVFDLETRTWSISPATGDVPHLScLGV 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   79 AMAAVGPIIYFFGGRDSTHQeLNELYCFNTLTNQWKLLSSGETGPQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNV 158
Cdd:PLN02193 223 RMVSIGSTLYVFGGRDASRQ-YNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNI 301

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  159 VDQKWIKFPSPGEACRGRGGPGLEVVQGKIWVVYGFAGEEADDVHCFDIAKGEWKEVETKGEKPSARSVFSTAVVGKQIL 238
Cdd:PLN02193 302 VDKKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIV 381

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  239 ISGGEIDPSDLGHMGAGCFTGDAYGLDTETLEWRKWEDGVGSVEHPGPRGWCAFAAGSRDGKQGLLVYGGNSPSNDRLDD 318
Cdd:PLN02193 382 IFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSRGWTASTTGTIDGKKGLVMHGGKAPTNDRFDD 461


                 ....
gi 18398038  319 IFFF 322
Cdd:PLN02193 462 LFFY 465
 
Name Accession Description Interval E-value
PLN02193 PLN02193
nitrile-specifier protein
 1-322 5.10e-136

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 394.32  E-value: 5.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038    1 MAATP-MEGKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLETQTWSIQEASGDAPPPR-VGV 78
Cdd:PLN02193 143 LPSTPkLLGKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDKHLYVFDLETRTWSISPATGDVPHLScLGV 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   79 AMAAVGPIIYFFGGRDSTHQeLNELYCFNTLTNQWKLLSSGETGPQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNV 158
Cdd:PLN02193 223 RMVSIGSTLYVFGGRDASRQ-YNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNI 301

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  159 VDQKWIKFPSPGEACRGRGGPGLEVVQGKIWVVYGFAGEEADDVHCFDIAKGEWKEVETKGEKPSARSVFSTAVVGKQIL 238
Cdd:PLN02193 302 VDKKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIV 381

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  239 ISGGEIDPSDLGHMGAGCFTGDAYGLDTETLEWRKWEDGVGSVEHPGPRGWCAFAAGSRDGKQGLLVYGGNSPSNDRLDD 318
Cdd:PLN02193 382 IFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSRGWTASTTGTIDGKKGLVMHGGKAPTNDRFDD 461


                 ....
gi 18398038  319 IFFF 322
Cdd:PLN02193 462 LFFY 465
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
11-246 6.74e-28

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 109.48  E-value: 6.74e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  11 VQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRVPvdNQLYVFDLETQTWSiqeASGDAP-PPRVGVAMAAVGPIIYF 89
Cdd:COG3055   1 ATWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGSAS--NSFEVYDPATNTWS---ELAPLPgPPRHHAAAVAQDGKLYV 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  90 FGGRDSTH---QELNELYCFNTLTNQWkllSSGETGPQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNVVDQKWIKF 166
Cdd:COG3055  76 FGGFTGANpssTPLNDVYVYDPATNTW---TKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQL 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038 167 PSPGEACRG-----------------------------------RGGPGLEVVQGKIWVVYGFAGEEaDDVHCFDIAKGE 211
Cdd:COG3055 153 APLPTPRDHlaaavlpdgkilviggrngsgfsntwttlaplptaRAGHAAAVLGGKILVFGGESGFS-DEVEAYDPATNT 231

                       250       260       270
                ....*....|....*....|....*....|....*
gi 18398038 212 WKEVetkGEKPSARSVFSTAVVGKQILISGGEIDP 246
Cdd:COG3055 232 WTAL---GELPTPRHGHAAVLTDGKVYVIGGETKP 263
Kelch_3 pfam13415
Galactose oxidase, central domain;
32-83 4.06e-09

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 51.91  E-value: 4.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 18398038    32 GNKMYAFGGEFQPRVPVDNQLYVFDLETQTWsiqEASGDAPPPRVGVAMAAV 83
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
mutarot_permut TIGR03548
cyclically-permuted mutarotase family protein; Members of this protein family show essentially ...
 8-146 5.44e-03

cyclically-permuted mutarotase family protein; Members of this protein family show essentially full-length homology, cyclically permuted, to YjhT from Escherichia coli. YjhT was shown to act as a mutarotase for sialic acid, and by this ability to be able to act as a virulence factor. Members of the YjhT family (TIGR03547) and this cyclically-permuted family have multiple repeats of the beta-propeller-forming Kelch repeat.


Pssm-ID: 274642 [Multi-domain]  Cd Length: 331  Bit Score: 38.23  E-value: 5.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038     8 GKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEfQPRVPvDNQLYVFDLETQTWSIQEASGDAPPPRVGVAMAAVGPII 87
Cdd:TIGR03548 100 KEALIIETLPSLPVAFDNGSATYKDGKIYVGGGN-ANGKP-SNKFYCLDLSNDTSGWEELPEFPGEARVQPVCQALHGKL 177

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18398038    88 YFFGGRDS--THQELNELYCFNTLTNQWKLLSSgetgpqnrsyhSITADSQNVYVFGGCGV 146
Cdd:TIGR03548 178 YVFGGFQLggDAIIYTDGYAYSPKTNTWQTVAD-----------PVLSDGEPITLLGGNSV 227
 
Name Accession Description Interval E-value
PLN02193 PLN02193
nitrile-specifier protein
 1-322 5.10e-136

nitrile-specifier protein


Pssm-ID: 177844 [Multi-domain]  Cd Length: 470  Bit Score: 394.32  E-value: 5.10e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038    1 MAATP-MEGKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLETQTWSIQEASGDAPPPR-VGV 78
Cdd:PLN02193 143 LPSTPkLLGKWIKVEQKGEGPGLRCSHGIAQVGNKIYSFGGEFTPNQPIDKHLYVFDLETRTWSISPATGDVPHLScLGV 222

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   79 AMAAVGPIIYFFGGRDSTHQeLNELYCFNTLTNQWKLLSSGETGPQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNV 158
Cdd:PLN02193 223 RMVSIGSTLYVFGGRDASRQ-YNGFYSFDTTTNEWKLLTPVEEGPTPRSFHSMAADEENVYVFGGVSATARLKTLDSYNI 301

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  159 VDQKWIKFPSPGEACRGRGGPGLEVVQGKIWVVYGFAGEEADDVHCFDIAKGEWKEVETKGEKPSARSVFSTAVVGKQIL 238
Cdd:PLN02193 302 VDKKWFHCSTPGDSFSIRGGAGLEVVQGKVWVVYGFNGCEVDDVHYYDPVQDKWTQVETFGVRPSERSVFASAAVGKHIV 381

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  239 ISGGEIDPSDLGHMGAGCFTGDAYGLDTETLEWRKWEDGVGSVEHPGPRGWCAFAAGSRDGKQGLLVYGGNSPSNDRLDD 318
Cdd:PLN02193 382 IFGGEIAMDPLAHVGPGQLTDGTFALDTETLQWERLDKFGEEEETPSSRGWTASTTGTIDGKKGLVMHGGKAPTNDRFDD 461


                 ....
gi 18398038  319 IFFF 322
Cdd:PLN02193 462 LFFY 465
PLN02153 PLN02153
epithiospecifier protein
 1-326 5.55e-113

epithiospecifier protein


Pssm-ID: 177814 [Multi-domain]  Cd Length: 341  Bit Score: 331.18  E-value: 5.55e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038    1 MAATpMEGKWVQLKQKG-TGPGARSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLETQTWSIQEASGDapPPRV--- 76
Cdd:PLN02153   1 MAPT-LQGGWIKVEQKGgKGPGPRCSHGIAVVGDKLYSFGGELKPNEHIDKDLYVFDFNTHTWSIAPANGD--VPRIscl 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   77 GVAMAAVGPIIYFFGGRDStHQELNELYCFNTLTNQWKLLSS--GETGPQNRSYHSITADSQNVYVFGGCGVDG------ 148
Cdd:PLN02153  78 GVRMVAVGTKLYIFGGRDE-KREFSDFYSYDTVKNEWTFLTKldEEGGPEARTFHSMASDENHVYVFGGVSKGGlmktpe 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  149 RLNDLWAYNVVDQKWIKFPSPGEACRGRGGPGLEVVQGKIWVVYGFAGE---------EADDVHCFDIAKGEWKEVETKG 219
Cdd:PLN02153 157 RFRTIEAYNIADGKWVQLPDPGENFEKRGGAGFAVVQGKIWVVYGFATSilpggksdyESNAVQFFDPASGKWTEVETTG 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  220 EKPSARSVFSTAVVGKQILISGGEIDPSDLGHMGAGCFTGDAYGLDTETLEWRKwedgVGSVEHPG-PRGWCAFAAGSRD 298
Cdd:PLN02153 237 AKPSARSVFAHAVVGKYIIIFGGEVWPDLKGHLGPGTLSNEGYALDTETLVWEK----LGECGEPAmPRGWTAYTTATVY 312

                        330       340
                 ....*....|....*....|....*...
gi 18398038  299 GKQGLLVYGGNSPSNDRLDDIFFFTPNT 326
Cdd:PLN02153 313 GKNGLLMHGGKLPTNERTDDLYFYAVNS 340
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
11-246 6.74e-28

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 109.48  E-value: 6.74e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  11 VQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRVPvdNQLYVFDLETQTWSiqeASGDAP-PPRVGVAMAAVGPIIYF 89
Cdd:COG3055   1 ATWSSLPDLPTPRSEAAAALLDGKVYVAGGLSGGSAS--NSFEVYDPATNTWS---ELAPLPgPPRHHAAAVAQDGKLYV 75

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038  90 FGGRDSTH---QELNELYCFNTLTNQWkllSSGETGPQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNVVDQKWIKF 166
Cdd:COG3055  76 FGGFTGANpssTPLNDVYVYDPATNTW---TKLAPMPTPRGGATALLLDGKIYVVGGWDDGGNVAWVEVYDPATGTWTQL 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038 167 PSPGEACRG-----------------------------------RGGPGLEVVQGKIWVVYGFAGEEaDDVHCFDIAKGE 211
Cdd:COG3055 153 APLPTPRDHlaaavlpdgkilviggrngsgfsntwttlaplptaRAGHAAAVLGGKILVFGGESGFS-DEVEAYDPATNT 231

                       250       260       270
                ....*....|....*....|....*....|....*
gi 18398038 212 WKEVetkGEKPSARSVFSTAVVGKQILISGGEIDP 246
Cdd:COG3055 232 WTAL---GELPTPRHGHAAVLTDGKVYVIGGETKP 263
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
123-308 5.08e-18

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 82.51  E-value: 5.08e-18
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038 123 PQNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNVVDQKWIKFPS-PGEAcrgRGGPGLEVVQGKIWVVYGFAGEEA-- 199
Cdd:COG3055  10 PTPRSEAAAALLDGKVYVAGGLSGGSASNSFEVYDPATNTWSELAPlPGPP---RHHAAAVAQDGKLYVFGGFTGANPss 86

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038 200 ---DDVHCFDIAKGEWKEVetkGEKPSARSVFSTAVVGKQILISGGEIDPSdlghmgagcFTGDAYGLDTETLEWRKwed 276
Cdd:COG3055  87 tplNDVYVYDPATNTWTKL---APMPTPRGGATALLLDGKIYVVGGWDDGG---------NVAWVEVYDPATGTWTQ--- 151

                       170       180       190
                ....*....|....*....|....*....|..
gi 18398038 277 gVGSVehPGPRGWCAfAAGSRDGKqgLLVYGG 308
Cdd:COG3055 152 -LAPL--PTPRDHLA-AAVLPDGK--ILVIGG 177
PHA03098 PHA03098
kelch-like protein; Provisional
 22-213 3.92e-13

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 69.80  E-value: 3.92e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   22 ARSSHAIALVGNKMYAFGGefqprvpVDNQLYVFDLETqtWSIQEAS-GDAPP---PRVGVAMAAVGPIIYFFGGRDSTH 97
Cdd:PHA03098 332 PRKNPGVTVFNNRIYVIGG-------IYNSISLNTVES--WKPGESKwREEPPlifPRYNPCVVNVNNLIYVIGGISKND 402

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   98 QELNELYCFNTLTNQWKLLSSgetGPQNRSYHSITADSQNVYVFGGCGV---DGRLNDLWAYNVVDQKWIKFPSpgeACR 174
Cdd:PHA03098 403 ELLKTVECFSLNTNKWSKGSP---LPISHYGGCAIYHDGKIYVIGGISYidnIKVYNIVESYNPVTNKWTELSS---LNF 476

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 18398038  175 GRGGPGLEVVQGKIWVVYGFAGEEA-DDVHCFDIAKGEWK 213
Cdd:PHA03098 477 PRINASLCIFNNKIYVVGGDKYEYYiNEIEVYDDKTNTWT 516
PHA03098 PHA03098
kelch-like protein; Provisional
 86-242 2.41e-10

kelch-like protein; Provisional


Pssm-ID: 222983 [Multi-domain]  Cd Length: 534  Bit Score: 61.32  E-value: 2.41e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   86 IIYFFGGRDSTHQELNELYCFNTLTNQWKLLSSGETgpqNRSYHSITADSQNVYVFGGCGVDGRLNDLWAYNVVDQKWIK 165
Cdd:PHA03098 296 VIYFIGGMNKNNLSVNSVVSYDTKTKSWNKVPELIY---PRKNPGVTVFNNRIYVIGGIYNSISLNTVESWKPGESKWRE 372

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18398038  166 FPSPGEAcrgRGGPGLEVVQGKIWVVYGFA--GEEADDVHCFDIAKGEWKeveTKGEKPSARSVFSTAVVGKQILISGG 242
Cdd:PHA03098 373 EPPLIFP---RYNPCVVNVNNLIYVIGGISknDELLKTVECFSLNTNKWS---KGSPLPISHYGGCAIYHDGKIYVIGG 445
Kelch_3 pfam13415
Galactose oxidase, central domain;
32-83 4.06e-09

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 51.91  E-value: 4.06e-09
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 18398038    32 GNKMYAFGGEFQPRVPVDNQLYVFDLETQTWsiqEASGDAPPPRVGVAMAAV 83
Cdd:pfam13415   1 GDKLYIFGGLGFDGQTRLNDLYVYDLDTNTW---TQIGDLPPPRSGHSATYI 49
Kelch_4 pfam13418
Galactose oxidase, central domain;
126-163 2.21e-07

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 46.84  E-value: 2.21e-07
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 18398038   126 RSYHSITA-DSQNVYVFGGCGVDG-RLNDLWAYNVVDQKW 163
Cdd:pfam13418   2 RAYHTSTSiPDDTIYLFGGEGEDGtLLSDLWVFDLSTNEW 41
NanM COG3055
N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];
7-92 3.54e-07

N-acetylneuraminic acid mutarotase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442289 [Multi-domain]  Cd Length: 277  Bit Score: 50.92  E-value: 3.54e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038   7 EGKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEFQPRvpvdNQLYVFDLETQTWSiqeASGDAPPPRVGVAMAAVGPI 86
Cdd:COG3055 181 SGFSNTWTTLAPLPTARAGHAAAVLGGKILVFGGESGFS----DEVEAYDPATNTWT---ALGELPTPRHGHAAVLTDGK 253


                ....*.
gi 18398038  87 IYFFGG 92
Cdd:COG3055 254 VYVIGG 259
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 126-170 2.31e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 43.75  E-value: 2.31e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 18398038   126 RSYHSITADSQNVYVFGGCGVDGRLNDLWAYNVVDQKWIKFPSPG 170
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQSLNSVEVYDPETNTWSKLPSMP 46
Kelch_3 pfam13415
Galactose oxidase, central domain;
87-134 2.64e-06

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 43.82  E-value: 2.64e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 18398038    87 IYFFGGRDSTHQE-LNELYCFNTLTNQWKLLSsgeTGPQNRSYHSITAD 134
Cdd:pfam13415   4 LYIFGGLGFDGQTrLNDLYVYDLDTNTWTQIG---DLPPPRSGHSATYI 49
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 74-118 3.39e-06

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 43.37  E-value: 3.39e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 18398038    74 PRVGVAMAAVGPIIYFFGGRDStHQELNELYCFNTLTNQWKLLSS 118
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGGFDG-NQSLNSVEVYDPETNTWSKLPS 44
Kelch_6 pfam13964
Kelch motif;
22-75 9.45e-05

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 39.63  E-value: 9.45e-05
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....
gi 18398038    22 ARSSHAIALVGNKMYAFGGEFQPRVPVdNQLYVFDLETQTWsiqEASGDAPPPR 75
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPAL-NKLEVYNPLTKSW---EELPPLPTPR 50
Kelch_4 pfam13418
Galactose oxidase, central domain;
74-118 1.46e-04

Galactose oxidase, central domain;


Pssm-ID: 433191 [Multi-domain]  Cd Length: 49  Bit Score: 38.75  E-value: 1.46e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*.
gi 18398038    74 PRVGVAMAAVGP-IIYFFGGRDSTHQELNELYCFNTLTNQWKLLSS 118
Cdd:pfam13418   1 PRAYHTSTSIPDdTIYLFGGEGEDGTLLSDLWVFDLSTNEWTRLGS 46
Kelch_6 pfam13964
Kelch motif;
74-118 1.56e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 38.86  E-value: 1.56e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 18398038    74 PRVGVAMAAVGPIIYFFGGRDSTHQELNELYCFNTLTNQWKLLSS 118
Cdd:pfam13964   1 PRTFHSVVSVGGYIYVFGGYTNASPALNKLEVYNPLTKSWEELPP 45
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 22-64 1.65e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 38.75  E-value: 1.65e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|...
gi 18398038    22 ARSSHAIALVGNKMYAFGGeFQPRVPVDNqLYVFDLETQTWSI 64
Cdd:pfam01344   1 RRSGAGVVVVGGKIYVIGG-FDGNQSLNS-VEVYDPETNTWSK 41
Kelch_1 pfam01344
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 176-215 3.37e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 396078 [Multi-domain]  Cd Length: 46  Bit Score: 37.59  E-value: 3.37e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 18398038   176 RGGPGLEVVQGKIWVVYGFAGEEA-DDVHCFDIAKGEWKEV 215
Cdd:pfam01344   2 RSGAGVVVVGGKIYVIGGFDGNQSlNSVEVYDPETNTWSKL 42
Kelch_2 pfam07646
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 23-63 4.09e-04

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 462220 [Multi-domain]  Cd Length: 47  Bit Score: 37.70  E-value: 4.09e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 18398038    23 RSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLETQTWS 63
Cdd:pfam07646   2 RYPHASSVPGGKLYVVGGSDGLGDLSSSDVLVYDPETNVWT 42
Kelch_6 pfam13964
Kelch motif;
126-169 6.07e-04

Kelch motif;


Pssm-ID: 404790 [Multi-domain]  Cd Length: 50  Bit Score: 37.31  E-value: 6.07e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 18398038   126 RSYHSITADSQNVYVFGG-CGVDGRLNDLWAYNVVDQKWIKFPSP 169
Cdd:pfam13964   2 RTFHSVVSVGGYIYVFGGyTNASPALNKLEVYNPLTKSWEELPPL 46
Kelch_5 pfam13854
Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six ...
 20-59 1.44e-03

Kelch motif; The kelch motif was initially discovered in Kelch. In this protein there are six copies of the motif. It has been shown that Swiss:Q04652 is related to Galactose Oxidase for which a structure has been solved. The kelch motif forms a beta sheet. Several of these sheets associate to form a beta propeller structure as found in pfam00064, pfam00400 and pfam00415.


Pssm-ID: 433528 [Multi-domain]  Cd Length: 41  Bit Score: 36.00  E-value: 1.44e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 18398038    20 PGARSSHAIALVGNKMYAFGGEFQPRVPVDNQLYVFDLET 59
Cdd:pfam13854   1 PVPRYGHCAVTVGDYIYLYGGYTGGEGQPSDDVYVLSLPT 40
Kelch_3 pfam13415
Galactose oxidase, central domain;
138-175 1.71e-03

Galactose oxidase, central domain;


Pssm-ID: 433188 [Multi-domain]  Cd Length: 49  Bit Score: 35.73  E-value: 1.71e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 18398038   138 VYVFGGCGVDG--RLNDLWAYNVVDQKWIKFPSPGEACRG 175
Cdd:pfam13415   4 LYIFGGLGFDGqtRLNDLYVYDLDTNTWTQIGDLPPPRSG 43
mutarot_permut TIGR03548
cyclically-permuted mutarotase family protein; Members of this protein family show essentially ...
 8-146 5.44e-03

cyclically-permuted mutarotase family protein; Members of this protein family show essentially full-length homology, cyclically permuted, to YjhT from Escherichia coli. YjhT was shown to act as a mutarotase for sialic acid, and by this ability to be able to act as a virulence factor. Members of the YjhT family (TIGR03547) and this cyclically-permuted family have multiple repeats of the beta-propeller-forming Kelch repeat.


Pssm-ID: 274642 [Multi-domain]  Cd Length: 331  Bit Score: 38.23  E-value: 5.44e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18398038     8 GKWVQLKQKGTGPGARSSHAIALVGNKMYAFGGEfQPRVPvDNQLYVFDLETQTWSIQEASGDAPPPRVGVAMAAVGPII 87
Cdd:TIGR03548 100 KEALIIETLPSLPVAFDNGSATYKDGKIYVGGGN-ANGKP-SNKFYCLDLSNDTSGWEELPEFPGEARVQPVCQALHGKL 177

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 18398038    88 YFFGGRDS--THQELNELYCFNTLTNQWKLLSSgetgpqnrsyhSITADSQNVYVFGGCGV 146
Cdd:TIGR03548 178 YVFGGFQLggDAIIYTDGYAYSPKTNTWQTVAD-----------PVLSDGEPITLLGGNSV 227
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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