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Conserved domains on  [gi|1063716560|ref|NP_566986|]
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Tetratricopeptide repeat (TPR)-like superfamily protein [Arabidopsis thaliana]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 11459274)

tetratricopeptide repeat (TPR) protein may adopt a right-handed helical structure with an amphipathic channel and may function as an interaction scaffold in the formation of multi-protein complexes

CATH:  1.25.40.10
Gene Ontology:  GO:0005515
PubMed:  10517866|30708253
SCOP:  3001345

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 161-363 1.04e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 161 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 237
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 238 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 317
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716560 318 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 363
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 161-363 1.04e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 161 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 237
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 238 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 317
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716560 318 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 363
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 160-358 1.22e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPlRVEAYHGLLmaySDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKllvAQIRVIEGKHSEALKLYQELVKEEPR 319
Cdd:TIGR02917 221 ALRP-NNIAVLLAL---ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK---ALVDFQKKNYEDARETLQDALKSAPE 293

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1063716560 320 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYR 358
Cdd:TIGR02917 294 YLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQAR 332
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 161-363 1.04e-14

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 73.61  E-value: 1.04e-14
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 161 EEEERALD---EHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEE 237
Cdd:COG2956    22 GQPDKAIDlleEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAEELLEK 101

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 238 ILAKDPLRVEAYHGLLMAYsdagLDLKEVESRIEEAmLKCKKENNQNDfrDFKLLVAQIRVIEGKHSEALKLYQELVKEE 317
Cdd:COG2956   102 LLELDPDDAEALRLLAEIY----EQEGDWEKAIEVL-ERLLKLGPENA--HAYCELAELYLEQGDYDEAIEALEKALKLD 174

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 1063716560 318 PRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMD 363
Cdd:COG2956   175 PDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 189-358 1.85e-13

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 70.14  E-value: 1.85e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 189 IKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVES 268
Cdd:COG2956    19 LLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAG-LLDRAEE 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 269 RIEEAMlkckkENNQNDfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFR 348
Cdd:COG2956    98 LLEKLL-----ELDPDD-AEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                         170
                  ....*....|
gi 1063716560 349 KLVPKNHPYR 358
Cdd:COG2956   172 KLDPDCARAL 181
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
175-384 5.14e-13

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 68.11  E-value: 5.14e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 175 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLM 254
Cdd:COG0457     5 PDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGL 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 255 AYSDAGldlkevesRIEEAMLKCKK--ENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYT 332
Cdd:COG0457    85 ALQALG--------RYEEALEDYDKalELDPDDAEALYNL-GLALLELGRYDEAIEAYERALELDPDDADALYNLGIALE 155

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|..
gi 1063716560 333 LLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATKLFSEKAQREMAEEMA 384
Cdd:COG0457   156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQAL 207
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 160-343 1.06e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 1.06e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG2956    92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPR 319
Cdd:COG2956   172 KLDPDCARALLLLAELYLEQG-DYEEAIAALERAL-----EQDPDYLPALPRL-AELYEKLGDPEEALELLRKALELDPS 244

                         170       180
                  ....*....|....*....|....
gi 1063716560 320 DfRPYLCQGIIYTLLKKKDKAEEQ 343
Cdd:COG2956   245 D-DLLLALADLLERKEGLEAALAL 267
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 176-354 3.73e-12

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 63.29  E-value: 3.73e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 176 SDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMA 255
Cdd:COG4783     2 ACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLA 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 256 YSDAGldlkevesrieeamlkckkennqndfrdfkllvaqirviegKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLK 335
Cdd:COG4783    82 LLKAG-----------------------------------------DYDEALALLEKALKLDPEHPEAYLRLARAYRALG 120

                         170
                  ....*....|....*....
gi 1063716560 336 KKDKAEEQFDNFRKLVPKN 354
Cdd:COG4783   121 RPDEAIAALEKALELDPDD 139
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 162-384 6.95e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 6.95e-12
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 162 EEERALDEH---LITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEI 238
Cdd:COG2956    57 EYDRAIRIHqklLERDPDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERL 136

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 239 LAKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEP 318
Cdd:COG2956   137 LKLGPENAHAYCELAELYLEQG-DYDEAIEALEKAL-----KLDPDCARALLLL-AELYLEQGDYEEAIAALERALEQDP 209

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 1063716560 319 RDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFmdNMIATKLFSEKAQREMAEEMA 384
Cdd:COG2956   210 DYLPALPRLAELYEKLGDPEEALELLRKALELDPSDDLLLALA--DLLERKEGLEAALALLERQLR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 160-274 1.76e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 1.76e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG4783    20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKAL 99

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAM 274
Cdd:COG4783   100 KLDPEHPEAYLRLARAYRALG-RPDEAIAALEKAL 133
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 162-260 1.22e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.22e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 162 EEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAK 241
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                          90
                  ....*....|....*....
gi 1063716560 242 DPLRVEAYHGLLMAYSDAG 260
Cdd:COG4235    81 DPDNPEALYLLGLAAFQQG 99
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 217-360 5.79e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 56.66  E-value: 5.79e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 217 LKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkEVEsRIEEAMLKCKKENNQNDFRDFKLlvAQI 296
Cdd:COG2956    13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRG----EYD-RAIRIHQKLLERDPDRAEALLEL--AQD 85

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 1063716560 297 RVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN-HPYREY 360
Cdd:COG2956    86 YLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENaHAYCEL 150
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 160-358 1.22e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 57.02  E-value: 1.22e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:TIGR02917 141 LELAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNIELALAAYRKAI 220

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPlRVEAYHGLLmaySDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKllvAQIRVIEGKHSEALKLYQELVKEEPR 319
Cdd:TIGR02917 221 ALRP-NNIAVLLAL---ATILIEAGEFEEAEKHADALLKKAPNSPLAHYLK---ALVDFQKKNYEDARETLQDALKSAPE 293

                         170       180       190
                  ....*....|....*....|....*....|....*....
gi 1063716560 320 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYR 358
Cdd:TIGR02917 294 YLPALLLAGASEYQLGNLEQAYQYLNQILKYAPNSHQAR 332
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 196-358 3.13e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.93  E-value: 3.13e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 196 EAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLlmaysdagldlkevesrieeaml 275
Cdd:COG4235     1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL----------------------- 57

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 276 kckkennqndfrdfkllvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNH 355
Cdd:COG4235    58 ------------------AEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119


                  ...
gi 1063716560 356 PYR 358
Cdd:COG4235   120 PAR 122
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 175-360 3.71e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 3.71e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 175 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKL-EPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGL- 252
Cdd:TIGR02917  87 YPKNQVLPLLARAYLLQGKFQQVLDELPGKTLLdDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPRSLYAKLGLa 166

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 253 --LMAYSdaglDLKEVESRIEEAMLKckkennQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGII 330
Cdd:TIGR02917 167 qlALAEN----RFDEARALIDEVLTA------DPGNVDALLLKGDLLLSLGNIELALAAYRKAIALRPNNIAVLLALATI 236

                         170       180       190
                  ....*....|....*....|....*....|
gi 1063716560 331 YTLLKKKDKAEEQFDNFRKLVPkNHPYREY 360
Cdd:TIGR02917 237 LIEAGEFEEAEKHADALLKKAP-NSPLAHY 265
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
239-360 1.00e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 49.62  E-value: 1.00e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 239 LAKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAMLKCKK--ENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKE 316
Cdd:COG0457     1 LELDPDDAEAYNNLGLAYRRLG--------RYEEAIEDYEKalELDPDDAEALYNL-GLAYLRLGRYEEALADYEQALEL 71

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 1063716560 317 EPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREY 360
Cdd:COG0457    72 DPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYN 115
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 160-260 1.02e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 50.76  E-value: 1.02e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG3914   128 LEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRAL 207

                          90       100
                  ....*....|....*....|.
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAG 260
Cdd:COG3914   208 ELDPDNADAHSNLLFALRQAC 228
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 294-384 1.36e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 1.36e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 294 AQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATKLFsE 373
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDY-D 89

                          90
                  ....*....|.
gi 1063716560 374 KAQREMAEEMA 384
Cdd:COG4783    90 EALALLEKALK 100
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 160-245 2.03e-06

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 47.26  E-value: 2.03e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG5010    70 FEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRAL 149


                  ....*.
gi 1063716560 240 AKDPLR 245
Cdd:COG5010   150 GTSPLK 155
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
160-343 2.40e-06

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 48.46  E-value: 2.40e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG0457    58 YEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL 137

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAMLKCKKENNQNdfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPR 319
Cdd:COG0457   138 ELDPDDADALYNLGIALEKLG--------RYEEALELLEKLEAAA--LAALLAAALGEAALALAAAEVLLALLLALEQAL 207

                         170       180
                  ....*....|....*....|....
gi 1063716560 320 DFRPYLCQGIIYTLLKKKDKAEEQ 343
Cdd:COG0457   208 RKKLAILTLAALAELLLLALALLL 231
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 160-274 5.49e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 48.45  E-value: 5.49e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG3914    94 YEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRAL 173

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAM 274
Cdd:COG3914   174 ELDPDNAEALNNLGNALQDLG--------RLEEAI 200
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 160-243 6.50e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 45.57  E-value: 6.50e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG4783    54 LDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133


                  ....
gi 1063716560 240 AKDP 243
Cdd:COG4783   134 ELDP 137
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 219-356 1.20e-05

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 44.80  E-value: 1.20e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 219 ANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLlmaysdagldlkevesrieeamlkckkennqndfrdfkllvAQIRV 298
Cdd:COG4783    11 AQALLLAGDYDEAEALLEKALELDPDNPEAFALL-----------------------------------------GEILL 49

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 1063716560 299 IEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPkNHP 356
Cdd:COG4783    50 QLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDP-EHP 106
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 161-356 3.30e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.23  E-value: 3.30e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 161 EEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILA 240
Cdd:TIGR02917 652 AKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALK 731

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 241 KDPLRVEAYhGLLMAYSDAGlDLKEVESRIeEAMLKckkeNNQNDFRdFKLLVAQIRVIEGKHSEALKLYQELVKEEPrD 320
Cdd:TIGR02917 732 RAPSSQNAI-KLHRALLASG-NTAEAVKTL-EAWLK----THPNDAV-LRTALAELYLAQKDYDKAIKHYQTVVKKAP-D 802

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063716560 321 FRPYLcQGIIYTLLKKKD-KAEEQFDNFRKLVPKNHP 356
Cdd:TIGR02917 803 NAVVL-NNLAWLYLELKDpRALEYAERALKLAPNIPA 838
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 160-273 3.41e-05

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 43.07  E-value: 3.41e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG4235    33 YDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112

                          90       100       110
                  ....*....|....*....|....*....|....
gi 1063716560 240 AKDPlrveayhgllmaysdAGLDLKEVESRIEEA 273
Cdd:COG4235   113 ALLP---------------ADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 160-356 4.88e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 45.46  E-value: 4.88e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:TIGR02917 311 LEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKAT 390

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckKENNQNDFRDFKLLVAQIRviEGKHSEALKLYQELVKEEPR 319
Cdd:TIGR02917 391 ELDPENAAARTQLGISKLSQG-DPSEAIADLETAA----QLDPELGRADLLLILSYLR--SGQFDKALAAAKKLEKKQPD 463

                         170       180       190
                  ....*....|....*....|....*....|....*..
gi 1063716560 320 DFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKNHP 356
Cdd:TIGR02917 464 NASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFP 500
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
219-382 6.12e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 43.75  E-value: 6.12e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 219 ANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkevesrieeamlkckkennqndfrDFKllvaqirv 298
Cdd:COG4785    80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLG---------------------------DYD-------- 124

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 299 iegkhsEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPkNHPYReYFMDNMIATKLFSEKAQRE 378
Cdd:COG4785   125 ------AALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALELDP-NDPER-ALWLYLAERKLDPEKALAL 196


                  ....
gi 1063716560 379 MAEE 382
Cdd:COG4785   197 LLED 200
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 175-369 1.01e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 1.01e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 175 PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLM 254
Cdd:TIGR02917 428 PELGRADLLLILSYLRSGQFDKALAAAKKLEKKQPDNASLHNLLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLAR 507

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 255 aysdagLDLKevESRIE------EAMLKCKKENNqndfrDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQG 328
Cdd:TIGR02917 508 ------IDIQ--EGNPDdaiqrfEKVLTIDPKNL-----RAILALAGLYLRTGNEEEAVAWLEKAAELNPQEIEPALALA 574

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|.
gi 1063716560 329 IIYTLLKKKDKAEEQFDNFRKLVPKNHPYREYFMDNMIATK 369
Cdd:TIGR02917 575 QYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAG 615
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
226-322 1.14e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 40.92  E-value: 1.14e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 226 GDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGldlkevesRIEEAmLKCKK--ENNQNDFRDFKLLvAQIRVIEGKH 303
Cdd:COG3063     6 GDLEEAEEYYEKALELDPDNADALNNLGLLLLEQG--------RYDEA-IALEKalKLDPNNAEALLNL-AELLLELGDY 75

                          90
                  ....*....|....*....
gi 1063716560 304 SEALKLYQELVKEEPRDFR 322
Cdd:COG3063    76 DEALAYLERALELDPSALR 94
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 190-274 2.35e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 41.10  E-value: 2.35e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 190 KSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVESR 269
Cdd:COG5010    66 KLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLG-QDDEAKAA 144


                  ....*
gi 1063716560 270 IEEAM 274
Cdd:COG5010   145 LQRAL 149
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
174-345 7.34e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 40.67  E-value: 7.34e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 174 HPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLL 253
Cdd:COG4785    69 LPDLAQLYYERGVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRG 148

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 254 MAYSDAGldlkevesRIEEA---MLKCKKENNQNDFRDFKLLVAQIRViegKHSEALKLYQELVkeeprdFRPYLCQGii 330
Cdd:COG4785   149 IALYYLG--------RYELAiadLEKALELDPNDPERALWLYLAERKL---DPEKALALLLEDW------ATAYLLQG-- 209

                         170
                  ....*....|....*
gi 1063716560 331 ytllkKKDKAEEQFD 345
Cdd:COG4785   210 -----DTEEARELFK 219
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
193-274 7.64e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 7.64e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 193 KLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTgFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEE 272
Cdd:COG3063     7 DLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELG-DYDEALAYLER 84


                  ..
gi 1063716560 273 AM 274
Cdd:COG3063    85 AL 86
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 235-354 8.43e-04

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.56  E-value: 8.43e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 235 FEEILAKDPLRVEAYHGLLMAYSDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELV 314
Cdd:COG5010     2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 1063716560 315 KEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN 354
Cdd:COG5010    82 QLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDN 121
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
160-243 1.00e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.23  E-value: 1.00e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEvIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG3063     8 LEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERAL 86


                  ....
gi 1063716560 240 AKDP 243
Cdd:COG3063    87 ELDP 90
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 160-318 1.14e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 39.17  E-value: 1.14e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:COG5010     2 RALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQAL 81

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENNQNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEP 318
Cdd:COG5010    82 QLDPNNPELYYNLALLYSRSG-DKDEAKEYYEKAL-----ALSPDNPNAYSNL-AALLLSLGQDDEAKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 166-354 1.18e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.22  E-value: 1.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 166 ALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLR 245
Cdd:TIGR02917 589 ILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRALELKPDN 668

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 246 VEAYHGLLMAY------SDAGLDLKEVESRIEEAMLKCKKENN----QNDFRD----FK------------LLVAQIRVI 299
Cdd:TIGR02917 669 TEAQIGLAQLLlaakrtESAKKIAKSLQKQHPKAALGFELEGDlylrQKDYPAaiqaYRkalkrapssqnaIKLHRALLA 748

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 1063716560 300 EGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVPKN 354
Cdd:TIGR02917 749 SGNTAEAVKTLEAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDN 803
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 160-342 1.47e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.84  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEIL 239
Cdd:TIGR02917 481 LAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAA 560

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkeNNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPR 319
Cdd:TIGR02917 561 ELNPQEIEPALALAQYYLGKG-QLKKALAILNEAA------DAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPD 633

                         170       180
                  ....*....|....*....|...
gi 1063716560 320 DFRPYLCQGIIYTLLKKKDKAEE 342
Cdd:TIGR02917 634 SALALLLLADAYAVMKNYAKAIT 656
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 203-352 1.99e-03

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 38.40  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 203 RLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVESRIEEAMlkckkENN 282
Cdd:COG5010    11 PLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLG-DFEESLALLEQAL-----QLD 84

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 283 QNDFRDFKLLvAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFRKLVP 352
Cdd:COG5010    85 PNNPELYYNL-ALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
160-317 2.61e-03

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 39.22  E-value: 2.61e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 160 LEEEERALDEHLITHPSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAktgfEEIL 239
Cdd:COG0457    92 YEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEA----LELL 167

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 1063716560 240 AKDPLRVEAYHGLLMAYSDAGLDLKEVESRIEEAMLKCKKENNQNDFRDFKLLVAQIRVIEGKHSEALKLYQELVKEE 317
Cdd:COG0457   168 EKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALALYQYRA 245
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 151-345 5.08e-03

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 38.81  E-value: 5.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 151 SVESKENVTLEEEERALDEHLITH---PSDVDALRSLMEVKIKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGD 227
Cdd:TIGR00990 301 SPESKADESYEEAARAFEKALDLGklgEKEAIALNLRGTFKCLKGKHLEALADLSKSIELDPRVTQSYIKRASMNLELGD 380

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 228 LDLAKTGFEEILAKDPLRVEAY------HGLLMAYSDAGLDLKevesrieeamlKCKKENNQNDFRDFKLLVAQIRviEG 301
Cdd:TIGR00990 381 PDKAEEDFDKALKLNSEDPDIYyhraqlHFIKGEFAQAGKDYQ-----------KSIDLDPDFIFSHIQLGVTQYK--EG 447

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 1063716560 302 KHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFD 345
Cdd:TIGR00990 448 SIASSMATFRRCKKNFPEAPDVYNYYGELLLDQNKFDEAIEKFD 491
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 189-356 6.17e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 38.91  E-value: 6.17e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 189 IKSRKLTEAVEVIDRLIKLEPEEKEWPVLKANIFTYSGDLDLAKTGFEEILAKDPLRVEAYHGLLMAYSDAGlDLKEVES 268
Cdd:TIGR02917 476 LGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTG-NEEEAVA 554

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 1063716560 269 RIEEAMlkckKENNQNdfRDFKLLVAQIRVIEGKHSEALKLYQELVKEEPRDFRPYLCQGIIYTLLKKKDKAEEQFDNFR 348
Cdd:TIGR02917 555 WLEKAA----ELNPQE--IEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL 628


                  ....*...
gi 1063716560 349 KLVPKNHP 356
Cdd:TIGR02917 629 ALQPDSAL 636
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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