Alternative oxidase family protein [Arabidopsis thaliana]
Protein Classification
alternative oxidase( domain architecture ID 10099399)
alternative oxidase, also called ubiquinol oxidase, catalyzes the cyanide-resistant oxidation of ubiquinol and the reduction of molecular oxygen to water, but does not translocate protons and consequently is not linked to oxidative phosphorylation; belongs to a broad superfamily of ferritin-like diiron-carboxylate proteins
List of domain hits
| Name | Accession | Description | Interval | E-value | ||||
| AOX | cd01053 | Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a ... |
124-310 | 8.08e-98 | ||||
Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a mitochondrial ubiquinol oxidase found in plants and some fungi and protists. AOX is a member of the ferritin-like diiron-carboxylate superfamily. The plant mitochondrial protein alternative oxidase catalyses dioxygen dependent ubiquinol oxidation to yield ubiquinone and water. AOX is a cyanide-resistant, salicylhydroxamic acid-sensitive oxidase that transfers electrons from ubiquinol to oxygen, bypassing the cytochrome chain. AOX has been proposed to contain a hydroxo-bridged diiron center within a four-helix bundle and a proximal redox-active tyrosine residue. AOX is proposed to be peripherally associated with the matrix side of the inner mitochondrial membrane. Fungal and protozoan AOXs generally exist as monomers. In plants, AOX is dimeric. Pyruvate is an allosteric activator of plant AOX involved in the reversible inactivation of the enzyme though the formation of an intermolecular disulfide bridge between monomeric subunits. The enzyme is non-proton-motive and does not contribute to the conservation of energy. The heat that dissipates from AOX activity is used in thermogenic plants to volatilize primary amines to attract pollinating insects. Other functions have been proposed: i) that the alternative oxidase allows Krebs-cycle turnover when the energy charge of the cell is high, and ii) that the enzyme protects against oxidative stress. The expression of AOX is induced when plants are exposed to a variety of stresses including chilling, pathogen attack, senescence and fruit ripening. : Pssm-ID: 153112 Cd Length: 168 Bit Score: 286.80 E-value: 8.08e-98
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| Name | Accession | Description | Interval | E-value | ||||
| AOX | cd01053 | Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a ... |
124-310 | 8.08e-98 | ||||
Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a mitochondrial ubiquinol oxidase found in plants and some fungi and protists. AOX is a member of the ferritin-like diiron-carboxylate superfamily. The plant mitochondrial protein alternative oxidase catalyses dioxygen dependent ubiquinol oxidation to yield ubiquinone and water. AOX is a cyanide-resistant, salicylhydroxamic acid-sensitive oxidase that transfers electrons from ubiquinol to oxygen, bypassing the cytochrome chain. AOX has been proposed to contain a hydroxo-bridged diiron center within a four-helix bundle and a proximal redox-active tyrosine residue. AOX is proposed to be peripherally associated with the matrix side of the inner mitochondrial membrane. Fungal and protozoan AOXs generally exist as monomers. In plants, AOX is dimeric. Pyruvate is an allosteric activator of plant AOX involved in the reversible inactivation of the enzyme though the formation of an intermolecular disulfide bridge between monomeric subunits. The enzyme is non-proton-motive and does not contribute to the conservation of energy. The heat that dissipates from AOX activity is used in thermogenic plants to volatilize primary amines to attract pollinating insects. Other functions have been proposed: i) that the alternative oxidase allows Krebs-cycle turnover when the energy charge of the cell is high, and ii) that the enzyme protects against oxidative stress. The expression of AOX is induced when plants are exposed to a variety of stresses including chilling, pathogen attack, senescence and fruit ripening. Pssm-ID: 153112 Cd Length: 168 Bit Score: 286.80 E-value: 8.08e-98
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| AOX | pfam01786 | Alternative oxidase; The alternative oxidase is used as a second terminal oxidase in the ... |
102-308 | 3.91e-57 | ||||
Alternative oxidase; The alternative oxidase is used as a second terminal oxidase in the mitochondria, electrons are transfered directly from reduced ubiquinol to oxygen forming water. This is not coupled to ATP synthesis and is not inhibited by cyanide, this pathway is a single step process. In rice the transcript levels of the alternative oxidase are increased by low temperature. Pssm-ID: 460328 Cd Length: 218 Bit Score: 184.67 E-value: 3.91e-57
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| PLN02478 | PLN02478 | alternative oxidase |
71-299 | 3.93e-15 | ||||
alternative oxidase Pssm-ID: 215265 Cd Length: 328 Bit Score: 75.32 E-value: 3.93e-15
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| Name | Accession | Description | Interval | E-value | ||||
| AOX | cd01053 | Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a ... |
124-310 | 8.08e-98 | ||||
Alternative oxidase, ferritin-like diiron-binding domain; Alternative oxidase (AOX) is a mitochondrial ubiquinol oxidase found in plants and some fungi and protists. AOX is a member of the ferritin-like diiron-carboxylate superfamily. The plant mitochondrial protein alternative oxidase catalyses dioxygen dependent ubiquinol oxidation to yield ubiquinone and water. AOX is a cyanide-resistant, salicylhydroxamic acid-sensitive oxidase that transfers electrons from ubiquinol to oxygen, bypassing the cytochrome chain. AOX has been proposed to contain a hydroxo-bridged diiron center within a four-helix bundle and a proximal redox-active tyrosine residue. AOX is proposed to be peripherally associated with the matrix side of the inner mitochondrial membrane. Fungal and protozoan AOXs generally exist as monomers. In plants, AOX is dimeric. Pyruvate is an allosteric activator of plant AOX involved in the reversible inactivation of the enzyme though the formation of an intermolecular disulfide bridge between monomeric subunits. The enzyme is non-proton-motive and does not contribute to the conservation of energy. The heat that dissipates from AOX activity is used in thermogenic plants to volatilize primary amines to attract pollinating insects. Other functions have been proposed: i) that the alternative oxidase allows Krebs-cycle turnover when the energy charge of the cell is high, and ii) that the enzyme protects against oxidative stress. The expression of AOX is induced when plants are exposed to a variety of stresses including chilling, pathogen attack, senescence and fruit ripening. Pssm-ID: 153112 Cd Length: 168 Bit Score: 286.80 E-value: 8.08e-98
|
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| AOX | pfam01786 | Alternative oxidase; The alternative oxidase is used as a second terminal oxidase in the ... |
102-308 | 3.91e-57 | ||||
Alternative oxidase; The alternative oxidase is used as a second terminal oxidase in the mitochondria, electrons are transfered directly from reduced ubiquinol to oxygen forming water. This is not coupled to ATP synthesis and is not inhibited by cyanide, this pathway is a single step process. In rice the transcript levels of the alternative oxidase are increased by low temperature. Pssm-ID: 460328 Cd Length: 218 Bit Score: 184.67 E-value: 3.91e-57
|
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| PLN02478 | PLN02478 | alternative oxidase |
71-299 | 3.93e-15 | ||||
alternative oxidase Pssm-ID: 215265 Cd Length: 328 Bit Score: 75.32 E-value: 3.93e-15
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