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Conserved domains on  [gi|18417421|ref|NP_568302|]
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S-adenosyl-L-methionine-dependent methyltransferases superfamily protein [Arabidopsis thaliana]

Protein Classification

tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A( domain architecture ID 10554888)

tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
GCD14 pfam08704
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase ...
 69-314 7.67e-151

tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase complex and is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.


:

Pssm-ID: 312288  Cd Length: 242  Bit Score: 423.06  E-value: 7.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421    69 KFVYLLAPTPELWTLVLSHRTQILYIADISFVVMYLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVS 148
Cdd:pfam08704   1 GFVYVLQPTPELWTLNLPHRTQILYTPDISLITMMLELRPGSVVCESGTGSGSLSHAIIRTVAPTGHLFTFEFHEQRADK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   149 AREDFEKTGISSLVTVEVRDIQGEGFPEKLSGLADSVFLDLPQPWLAVPSAAKMLK-QDGVLCSFSPCIEQVQRTCEVLR 227
Cdd:pfam08704  81 AREEFREHGIDQLVTVTHRDVCKEGFLTEVSGKADAVFLDLPSPWEAVPHAWKALKvEGGRFCSFSPCIEQVQRTCQALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   228 S-DFIEIRTFEVLLRTYEVKEVKMDTSSMvGESHEEDNEGMRPCKRkhrsnENDTVSQDNSSNASSVVMARPCSEARGHT 306
Cdd:pfam08704 161 ElGFTEISTLEVLLRVYDVRTVSLPVIDL-GIDREKENERTRTEGL-----SNDDKSEDNSGNSMLGTALKPMSEAVGHT 234


                  ....*...
gi 18417421   307 GYLTFARL 314
Cdd:pfam08704 235 GYLTFATK 242
 
Name Accession Description Interval E-value
GCD14 pfam08704
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase ...
 69-314 7.67e-151

tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase complex and is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.


Pssm-ID: 312288  Cd Length: 242  Bit Score: 423.06  E-value: 7.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421    69 KFVYLLAPTPELWTLVLSHRTQILYIADISFVVMYLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVS 148
Cdd:pfam08704   1 GFVYVLQPTPELWTLNLPHRTQILYTPDISLITMMLELRPGSVVCESGTGSGSLSHAIIRTVAPTGHLFTFEFHEQRADK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   149 AREDFEKTGISSLVTVEVRDIQGEGFPEKLSGLADSVFLDLPQPWLAVPSAAKMLK-QDGVLCSFSPCIEQVQRTCEVLR 227
Cdd:pfam08704  81 AREEFREHGIDQLVTVTHRDVCKEGFLTEVSGKADAVFLDLPSPWEAVPHAWKALKvEGGRFCSFSPCIEQVQRTCQALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   228 S-DFIEIRTFEVLLRTYEVKEVKMDTSSMvGESHEEDNEGMRPCKRkhrsnENDTVSQDNSSNASSVVMARPCSEARGHT 306
Cdd:pfam08704 161 ElGFTEISTLEVLLRVYDVRTVSLPVIDL-GIDREKENERTRTEGL-----SNDDKSEDNSGNSMLGTALKPMSEAVGHT 234


                  ....*...
gi 18417421   307 GYLTFARL 314
Cdd:pfam08704 235 GYLTFATK 242
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 19-313 6.73e-79

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 240.45  E-value: 6.73e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  19 GDLVIVYERHDVMKPVKVSKDGVLQNRFGVYKHSDWIGKPLGTKVFSNKGKFVYLLAPTPELWTLVLSHRTQILYIADIS 98
Cdd:COG2519   2 GDRVLLTDPKGRKYLVRLEEGKKFHTHKGIIDHDDLIGKPEGSVVTTSKGKEFLVLRPTLYDYVLSMKRGTQIIYPKDAG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  99 FVVMYLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDIQgEGFPEkl 178
Cdd:COG2519  82 YIIARLDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIR-EGIDE-- 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 179 sGLADSVFLDLPQPWLAVPSAAKMLKQDGVLCSFSPCIEQVQRTCEVLR-SDFIEIRTFEVLLRTYEVKEvkmdtssmvg 257
Cdd:COG2519 159 -GDVDAVFLDMPDPWEALEAVAKALKPGGVLVAYVPTVNQVSKLVEALReSGFTDIEAVETLLREWKVEG---------- 227

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 18417421 258 esheednEGMRPckrKHRsnendtvsqdnssnassvvMArpcsearGHTGYLTFAR 313
Cdd:COG2519 228 -------LAVRP---EHR-------------------MV-------GHTGFLVFAR 247
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
102-209 7.78e-06

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 45.97  E-value: 7.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  102 MYLEVVPGCVVLESGTGSGSLSTSLARAVaptGHVYSFDFHEQRAVSAREDFEKTGISSlvtVEVRDIQG-EGFPEKlsG 180
Cdd:PRK00312  72 ELLELKPGDRVLEIGTGSGYQAAVLAHLV---RRVFSVERIKTLQWEAKRRLKQLGLHN---VSVRHGDGwKGWPAY--A 143

                         90       100       110
                 ....*....|....*....|....*....|....
gi 18417421  181 LADSV-----FLDLPQPWLavpsaaKMLKQDGVL 209
Cdd:PRK00312 144 PFDRIlvtaaAPEIPRALL------EQLKEGGIL 171
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 93-171 6.02e-05

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 43.28  E-value: 6.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421    93 YIADISFVVM---YLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDI 169
Cdd:TIGR00080  59 TISAPHMVAMmteLLELKPGMKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRKLGLDNVIVIVGDGT 138


                  ..
gi 18417421   170 QG 171
Cdd:TIGR00080 139 QG 140
 
Name Accession Description Interval E-value
GCD14 pfam08704
tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase ...
 69-314 7.67e-151

tRNA methyltransferase complex GCD14 subunit; GCD14 is a subunit of the tRNA methyltransferase complex and is required for 1-methyladenosine modification and maturation of initiator methionyl-tRNA.


Pssm-ID: 312288  Cd Length: 242  Bit Score: 423.06  E-value: 7.67e-151
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421    69 KFVYLLAPTPELWTLVLSHRTQILYIADISFVVMYLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVS 148
Cdd:pfam08704   1 GFVYVLQPTPELWTLNLPHRTQILYTPDISLITMMLELRPGSVVCESGTGSGSLSHAIIRTVAPTGHLFTFEFHEQRADK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   149 AREDFEKTGISSLVTVEVRDIQGEGFPEKLSGLADSVFLDLPQPWLAVPSAAKMLK-QDGVLCSFSPCIEQVQRTCEVLR 227
Cdd:pfam08704  81 AREEFREHGIDQLVTVTHRDVCKEGFLTEVSGKADAVFLDLPSPWEAVPHAWKALKvEGGRFCSFSPCIEQVQRTCQALA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   228 S-DFIEIRTFEVLLRTYEVKEVKMDTSSMvGESHEEDNEGMRPCKRkhrsnENDTVSQDNSSNASSVVMARPCSEARGHT 306
Cdd:pfam08704 161 ElGFTEISTLEVLLRVYDVRTVSLPVIDL-GIDREKENERTRTEGL-----SNDDKSEDNSGNSMLGTALKPMSEAVGHT 234


                  ....*...
gi 18417421   307 GYLTFARL 314
Cdd:pfam08704 235 GYLTFATK 242
Gcd14 COG2519
tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 ...
 19-313 6.73e-79

tRNA A58 N-methylase Trm61 [Translation, ribosomal structure and biogenesis]; tRNA A58 N-methylase Trm61 is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 442009 [Multi-domain]  Cd Length: 249  Bit Score: 240.45  E-value: 6.73e-79
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  19 GDLVIVYERHDVMKPVKVSKDGVLQNRFGVYKHSDWIGKPLGTKVFSNKGKFVYLLAPTPELWTLVLSHRTQILYIADIS 98
Cdd:COG2519   2 GDRVLLTDPKGRKYLVRLEEGKKFHTHKGIIDHDDLIGKPEGSVVTTSKGKEFLVLRPTLYDYVLSMKRGTQIIYPKDAG 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  99 FVVMYLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDIQgEGFPEkl 178
Cdd:COG2519  82 YIIARLDIFPGARVLEAGTGSGALTLALARAVGPEGKVYSYERREDFAEIARKNLERFGLPDNVELKLGDIR-EGIDE-- 158

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 179 sGLADSVFLDLPQPWLAVPSAAKMLKQDGVLCSFSPCIEQVQRTCEVLR-SDFIEIRTFEVLLRTYEVKEvkmdtssmvg 257
Cdd:COG2519 159 -GDVDAVFLDMPDPWEALEAVAKALKPGGVLVAYVPTVNQVSKLVEALReSGFTDIEAVETLLREWKVEG---------- 227

                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 18417421 258 esheednEGMRPckrKHRsnendtvsqdnssnassvvMArpcsearGHTGYLTFAR 313
Cdd:COG2519 228 -------LAVRP---EHR-------------------MV-------GHTGFLVFAR 247
Pcm COG2518
Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, ...
 104-209 4.04e-09

Protein-L-isoaspartate O-methyltransferase [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 442008 [Multi-domain]  Cd Length: 197  Bit Score: 55.48  E-value: 4.04e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 104 LEVVPGCVVLESGTGSGSLSTSLARAVaptGHVYSFDFHEQRAVSAREDFEKTGISSlVTVEVRDiqG-EGFPEK----- 177
Cdd:COG2518  62 LDLKPGDRVLEIGTGSGYQAAVLARLA---GRVYSVERDPELAERARERLAALGYDN-VTVRVGD--GaLGWPEHapfdr 135

                        90       100       110
                ....*....|....*....|....*....|....
gi 18417421 178 --LSGLADSVfldlPQPWLAvpsaakMLKQDGVL 209
Cdd:COG2518 136 iiVTAAAPEV----PEALLE------QLAPGGRL 159
TrmR COG4122
tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; ...
 112-188 1.87e-08

tRNA 5-hydroxyU34 O-methylase TrmR/YrrM [Translation, ribosomal structure and biogenesis]; tRNA 5-hydroxyU34 O-methylase TrmR/YrrM is part of the Pathway/BioSystem: tRNA modification


Pssm-ID: 443298  Cd Length: 173  Bit Score: 53.26  E-value: 1.87e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 112 VLESGTGSGsLST-SLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVevrdIQGEGFpEKLSGLADS----VF 186
Cdd:COG4122  20 ILEIGTGTG-YSTlWLARALPDDGRLTTIEIDPERAAIARENFARAGLADRIRL----ILGDAL-EVLPRLADGpfdlVF 93


                ..
gi 18417421 187 LD 188
Cdd:COG4122  94 ID 95
Methyltransf_31 pfam13847
Methyltransferase domain; This family appears to have methyltransferase activity.
 108-244 2.73e-08

Methyltransferase domain; This family appears to have methyltransferase activity.


Pssm-ID: 463998 [Multi-domain]  Cd Length: 150  Bit Score: 52.03  E-value: 2.73e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   108 PGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFhEQRAVS-AREDFEKTGISSlVTVEVRDIqgEGFPEKLSG------ 180
Cdd:pfam13847   3 KGMRVLDLGCGTGHLSFELAEELGPNAEVVGIDI-SEEAIEkARENAQKLGFDN-VEFEQGDI--EELPELLEDdkfdvv 78

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18417421   181 LADSVFLDLPQPWLAVPSAAKMLKQDGVLCSFSPC-----IEQVQRTCEVLRSDFIEIRTFEVLLRTYE 244
Cdd:pfam13847  79 ISNCVLNHIPDPDKVLQEILRVLKPGGRLIISDPDslaelPAHVKEDSTYYAGCVGGAILKKKLYELLE 147
CobL COG2242
Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part ...
 104-186 2.63e-07

Precorrin-6B methylase 2 [Coenzyme transport and metabolism]; Precorrin-6B methylase 2 is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 441843 [Multi-domain]  Cd Length: 403  Bit Score: 51.71  E-value: 2.63e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 104 LEVVPGCVVLESGTGSGSLSTSLARAvAPTGHVYSFDFHEQRAVSAREDFEKTGISslvtvEVRDIQGEGfPEKLSGL-- 181
Cdd:COG2242 243 LALRPGDVLWDIGAGSGSVSIEAARL-APGGRVYAIERDPERAALIRANARRFGVP-----NVEVVEGEA-PEALADLpd 315


                ....*
gi 18417421 182 ADSVF 186
Cdd:COG2242 316 PDAVF 320
PCMT pfam01135
Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);
93-165 4.30e-07

Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT);


Pssm-ID: 395902 [Multi-domain]  Cd Length: 205  Bit Score: 49.67  E-value: 4.30e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18417421    93 YIADISFVVM---YLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVE 165
Cdd:pfam01135  55 TISAPHMHAMmleLLELKPGMRVLEIGSGSGYLTACFARMVGEVGRVVSIEHIPELVEIARRNLEKLGLENVIVVV 130
COG4076 COG4076
Predicted RNA methylase [General function prediction only];
106-209 1.37e-06

Predicted RNA methylase [General function prediction only];


Pssm-ID: 443253 [Multi-domain]  Cd Length: 230  Bit Score: 48.49  E-value: 1.37e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 106 VVPGCVVLESGTGSGSLSTSLARAVAptGHVYSFDFHEQRAVSAREDFEKTGISSLVTV---EVRDIQgegFPEK----L 178
Cdd:COG4076  33 VKPGDVVLDIGTGSGLLSMLAARAGA--KKVYAVEVNPDIAAVARRIIAANGLSDRITVinaDATDLD---LPEKadviI 107

                        90       100       110
                ....*....|....*....|....*....|...
gi 18417421 179 SGLADSVFLDLPQpwLAVPSAAK--MLKQDGVL 209
Cdd:COG4076 108 SEMLDTALLDEGQ--VPILNHARkrLLKPGGRI 138
pcm PRK00312
protein-L-isoaspartate(D-aspartate) O-methyltransferase;
102-209 7.78e-06

protein-L-isoaspartate(D-aspartate) O-methyltransferase;


Pssm-ID: 178974 [Multi-domain]  Cd Length: 212  Bit Score: 45.97  E-value: 7.78e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  102 MYLEVVPGCVVLESGTGSGSLSTSLARAVaptGHVYSFDFHEQRAVSAREDFEKTGISSlvtVEVRDIQG-EGFPEKlsG 180
Cdd:PRK00312  72 ELLELKPGDRVLEIGTGSGYQAAVLAHLV---RRVFSVERIKTLQWEAKRRLKQLGLHN---VSVRHGDGwKGWPAY--A 143

                         90       100       110
                 ....*....|....*....|....*....|....
gi 18417421  181 LADSV-----FLDLPQPWLavpsaaKMLKQDGVL 209
Cdd:PRK00312 144 PFDRIlvtaaAPEIPRALL------EQLKEGGIL 171
pimt TIGR00080
protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all ...
 93-171 6.02e-05

protein-L-isoaspartate(D-aspartate) O-methyltransferase; This is an all-kingdom (but not all species) full-length ortholog enzyme for repairing aging proteins. Among the prokaryotes, the gene name is pcm. Among eukaryotes, pimt. [Protein fate, Protein modification and repair]


Pssm-ID: 272896 [Multi-domain]  Cd Length: 215  Bit Score: 43.28  E-value: 6.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421    93 YIADISFVVM---YLEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDI 169
Cdd:TIGR00080  59 TISAPHMVAMmteLLELKPGMKVLEIGTGSGYQAAVLAEIVGRDGLVVSIERIPELAEKAERRLRKLGLDNVIVIVGDGT 138


                  ..
gi 18417421   170 QG 171
Cdd:TIGR00080 139 QG 140
UbiG COG2227
2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and ...
 106-209 2.01e-04

2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase [Coenzyme transport and metabolism]; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase is part of the Pathway/BioSystem: Ubiquinone biosynthesis


Pssm-ID: 441829 [Multi-domain]  Cd Length: 126  Bit Score: 40.39  E-value: 2.01e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 106 VVPGCVVLESGTGSGSLSTSLARAVAptgHVYSFDFHEQRAVSAREDFEKTGIsslvTVEVRDIQGEGFPEklsGLADSV 185
Cdd:COG2227  22 LPAGGRVLDVGCGTGRLALALARRGA---DVTGVDISPEALEIARERAAELNV----DFVQGDLEDLPLED---GSFDLV 91

                        90       100
                ....*....|....*....|....*....
gi 18417421 186 FL-----DLPQPWLAVPSAAKMLKQDGVL 209
Cdd:COG2227  92 ICsevleHLPDPAALLRELARLLKPGGLL 120
PRK07580 PRK07580
Mg-protoporphyrin IX methyl transferase; Validated
 107-211 3.44e-04

Mg-protoporphyrin IX methyl transferase; Validated


Pssm-ID: 236059 [Multi-domain]  Cd Length: 230  Bit Score: 41.36  E-value: 3.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  107 VPGCVVLESGTGSGSLSTSLARAVAptgHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDIqgegfpEKLSGLADSV- 185
Cdd:PRK07580  62 LTGLRILDAGCGVGSLSIPLARRGA---KVVASDISPQMVEEARERAPEAGLAGNITFEVGDL------ESLLGRFDTVv 132

                         90       100       110
                 ....*....|....*....|....*....|
gi 18417421  186 ----FLDLPQpwlavPSAAKMLKQdgvLCS 211
Cdd:PRK07580 133 cldvLIHYPQ-----EDAARMLAH---LAS 154
UbiE COG2226
Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; ...
 100-210 7.34e-04

Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG [Coenzyme transport and metabolism]; Ubiquinone/menaquinone biosynthesis C-methylase UbiE/MenG is part of the Pathway/BioSystem: Biotin biosynthesis


Pssm-ID: 441828 [Multi-domain]  Cd Length: 143  Bit Score: 39.21  E-value: 7.34e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421 100 VVMYLEVVPGCVVLESGTGSGSLSTSLARAvapTGHVYSFDFHEQRAVSAREDFEKTGISslVTVEVRDIQGEGFPEkls 179
Cdd:COG2226  14 LLAALGLRPGARVLDLGCGTGRLALALAER---GARVTGVDISPEMLELARERAAEAGLN--VEFVVGDAEDLPFPD--- 85

                        90       100       110
                ....*....|....*....|....*....|....*.
gi 18417421 180 GLADSVFL-----DLPQPWLAVPSAAKMLKQDGVLC 210
Cdd:COG2226  86 GSFDLVISsfvlhHLPDPERALAEIARVLKPGGRLV 121
PRK13944 PRK13944
protein-L-isoaspartate O-methyltransferase; Provisional
 100-164 7.64e-04

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 140001  Cd Length: 205  Bit Score: 40.18  E-value: 7.64e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 18417421  100 VVMYLEVV---PGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTV 164
Cdd:PRK13944  61 VAMMCELIeprPGMKILEVGTGSGYQAAVCAEAIERRGKVYTVEIVKELAIYAAQNIERLGYWGVVEV 128
PRK08317 PRK08317
hypothetical protein; Provisional
 104-207 1.16e-03

hypothetical protein; Provisional


Pssm-ID: 181382 [Multi-domain]  Cd Length: 241  Bit Score: 39.92  E-value: 1.16e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  104 LEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREdfEKTGISSLVTVEVRDIQGEGFP-EKLSG-L 181
Cdd:PRK08317  15 LAVQPGDRVLDVGCGPGNDARELARRVGPEGRVVGIDRSEAMLALAKE--RAAGLGPNVEFVRGDADGLPFPdGSFDAvR 92

                         90       100
                 ....*....|....*....|....*.
gi 18417421  182 ADSVFLDLPQPWLAVPSAAKMLKQDG 207
Cdd:PRK08317  93 SDRVLQHLEDPARALAEIARVLRPGG 118
arsM PRK11873
arsenite methyltransferase;
108-172 1.65e-03

arsenite methyltransferase;


Pssm-ID: 237007 [Multi-domain]  Cd Length: 272  Bit Score: 39.55  E-value: 1.65e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18417421  108 PGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSlvtVEVRdiQGE 172
Cdd:PRK11873  77 PGETVLDLGSGGGFDCFLAARRVGPTGKVIGVDMTPEMLAKARANARKAGYTN---VEFR--LGE 136
cbiT PRK00377
cobalt-precorrin-6Y C(15)-methyltransferase; Provisional
 104-226 1.93e-03

cobalt-precorrin-6Y C(15)-methyltransferase; Provisional


Pssm-ID: 234740  Cd Length: 198  Bit Score: 38.62  E-value: 1.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421  104 LEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVevrdIQGEGfPEKLSGL-- 181
Cdd:PRK00377  36 LRLRKGDMILDIGCGTGSVTVEASLLVGETGKVYAVDKDEKAINLTRRNAEKFGVLNNIVL----IKGEA-PEILFTIne 110

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 18417421  182 -ADSVFL-----DLPQpwlAVPSAAKMLKQDGVLCSFSPCIEQVQRTCEVL 226
Cdd:PRK00377 111 kFDRIFIgggseKLKE---IISASWEIIKKGGRIVIDAILLETVNNALSAL 158
Cfa COG2230
Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport ...
 104-177 3.94e-03

Cyclopropane fatty-acyl-phospholipid synthase and related methyltransferases [Lipid transport and metabolism];


Pssm-ID: 441831 [Multi-domain]  Cd Length: 158  Bit Score: 37.22  E-value: 3.94e-03
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 18417421 104 LEVVPGCVVLESGTGSGSLSTSLARAvapTG-HVYSFDF-HEQRAVsAREDFEKTGISSLVTVEVRDIQGEGFPEK 177
Cdd:COG2230  47 LGLKPGMRVLDIGCGWGGLALYLARR---YGvRVTGVTLsPEQLEY-ARERAAEAGLADRVEVRLADYRDLPADGQ 118
PRK13942 PRK13942
protein-L-isoaspartate O-methyltransferase; Provisional
 104-168 4.76e-03

protein-L-isoaspartate O-methyltransferase; Provisional


Pssm-ID: 184409  Cd Length: 212  Bit Score: 37.69  E-value: 4.76e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18417421  104 LEVVPGCVVLESGTGSGSLSTSLARAVAPTGHVYSFDFHEQRAVSAREDFEKTGISSlVTVEVRD 168
Cdd:PRK13942  72 LDLKEGMKVLEIGTGSGYHAAVVAEIVGKSGKVVTIERIPELAEKAKKTLKKLGYDN-VEVIVGD 135
Methyltransf_12 pfam08242
Methyltransferase domain; Members of this family are SAM dependent methyltransferases.
 113-209 5.07e-03

Methyltransferase domain; Members of this family are SAM dependent methyltransferases.


Pssm-ID: 400515 [Multi-domain]  Cd Length: 98  Bit Score: 35.81  E-value: 5.07e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   113 LESGTGSGSLSTSLARAvAPTGHVYSFDFHEQRAVSAREDFEKTGISSLVTVEVRDIQGegfPEKLSGLAD-----SVFL 187
Cdd:pfam08242   1 LEIGCGTGTLLRALLEA-LPGLEYTGLDISPAALEAARERLAALGLLNAVRVELFQLDL---GELDPGSFDvvvasNVLH 76

                          90       100
                  ....*....|....*....|..
gi 18417421   188 DLPQPWLAVPSAAKMLKQDGVL 209
Cdd:pfam08242  77 HLADPRAVLRNIRRLLKPGGVL 98
Methyltransf_25 pfam13649
Methyltransferase domain; This family appears to be a methyltransferase domain.
 112-207 7.66e-03

Methyltransferase domain; This family appears to be a methyltransferase domain.


Pssm-ID: 463945 [Multi-domain]  Cd Length: 96  Bit Score: 35.23  E-value: 7.66e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18417421   112 VLESGTGSGSLSTSLARAVAptGHVYSFDFHEQRAVSAREDFEKTGISslVTVEVRDIQGEGFPEklsGLADSVF----- 186
Cdd:pfam13649   1 VLDLGCGTGRLTLALARRGG--ARVTGVDLSPEMLERARERAAEAGLN--VEFVQGDAEDLPFPD---GSFDLVVssgvl 73

                          90       100
                  ....*....|....*....|...
gi 18417421   187 --LDLPQPWLAVPSAAKMLKQDG 207
Cdd:pfam13649  74 hhLPDPDLEAALREIARVLKPGG 96
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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