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Conserved domains on  [gi|18418089|ref|NP_568339|]
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Tho complex subunit 7/Mft1p [Arabidopsis thaliana]

Protein Classification

THO complex subunit 7 family protein( domain architecture ID 10528924)

THO complex subunit 7 (THOC7) family protein is a component of the THO subcomplex of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and which specifically associates with spliced mRNA and not with unspliced pre-mRNA

Gene Ontology:  GO:0006397|GO:0008380|GO:0003723|GO:0000346|GO:0000347
PubMed:  12871933
TCDB:  3.A.22

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 28-165 1.46e-27

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


:

Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 102.34  E-value: 1.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089    28 DKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVIELDkeeDNYSECGRLAKAFLQELSAFEIPLLKSQVVVAANLREKENF 107
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSLD---STPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 18418089   108 NELKDETNRQIMQAQADIEDLKKQLEESKIERQQKEECEAIRKLISAQPPRSETQKVI 165
Cdd:pfam05615  78 EAEKEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
 
Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 28-165 1.46e-27

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 102.34  E-value: 1.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089    28 DKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVIELDkeeDNYSECGRLAKAFLQELSAFEIPLLKSQVVVAANLREKENF 107
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSLD---STPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 18418089   108 NELKDETNRQIMQAQADIEDLKKQLEESKIERQQKEECEAIRKLISAQPPRSETQKVI 165
Cdd:pfam05615  78 EAEKEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 108-197 1.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 1.74e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089 108 NELKDETNRQIMQAQADIEDLKKQLE--ESKIERQQKEECEAIRKLISAQPPRSETQKVIHELKKEIAELEAENTASWRL 185
Cdd:COG4942  19 ADAAAEAEAELEQLQQEIAELEKELAalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                        90
                ....*....|..
gi 18418089 186 LELRKKQFALLL 197
Cdd:COG4942  99 LEAQKEELAELL 110
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 105-221 4.83e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.73  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089    105 ENFNELKDETNRQIMQAQADIEDLKKQLE--ESKIERQQKEECEAIRKLISAQppRSETQKVIHELKKEIAELEAENTAS 182
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLErlEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERL 459

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 18418089    183 WRLLELRKKQFALLLHVVDELQETMEDEQ--KSMVEEMQRN 221
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAAERELAQLQarLDSLERLQEN 500
 
Name Accession Description Interval E-value
THOC7 pfam05615
Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export ...
 28-165 1.46e-27

Tho complex subunit 7; The Tho complex is involved in transcription elongation and mRNA export from the nucleus.


Pssm-ID: 461692 [Multi-domain]  Cd Length: 135  Bit Score: 102.34  E-value: 1.46e-27
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089    28 DKIIRNRLLTRTTTTRGEPPLKKLQKKFTSFVIELDkeeDNYSECGRLAKAFLQELSAFEIPLLKSQVVVAANLREKENF 107
Cdd:pfam05615   1 DELIKRRLLNDGLGLGEERPLKRLTKRFLKLCNSLD---STPEEIQALREDLLLDLAAFELSIEKSQLLAEANERERENY 77

                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 18418089   108 NELKDETNRQIMQAQADIEDLKKQLEESKIERQQKEECEAIRKLISAQPPRSETQKVI 165
Cdd:pfam05615  78 EAEKEEIEEEIEAVREEIEELKERLEEAKRTRKNREEYDALAEKINENPSREETEKQL 135
EnvC COG4942
Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, ...
 108-197 1.74e-03

Septal ring factor EnvC, activator of murein hydrolases AmiA and AmiB [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 443969 [Multi-domain]  Cd Length: 377  Bit Score: 38.98  E-value: 1.74e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089 108 NELKDETNRQIMQAQADIEDLKKQLE--ESKIERQQKEECEAIRKLISAQPPRSETQKVIHELKKEIAELEAENTASWRL 185
Cdd:COG4942  19 ADAAAEAEAELEQLQQEIAELEKELAalKKEEKALLKQLAALERRIAALARRIRALEQELAALEAELAELEKEIAELRAE 98

                        90
                ....*....|..
gi 18418089 186 LELRKKQFALLL 197
Cdd:COG4942  99 LEAQKEELAELL 110
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 105-221 4.83e-03

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 37.73  E-value: 4.83e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18418089    105 ENFNELKDETNRQIMQAQADIEDLKKQLE--ESKIERQQKEECEAIRKLISAQppRSETQKVIHELKKEIAELEAENTAS 182
Cdd:TIGR02168  382 ETLRSKVAQLELQIASLNNEIERLEARLErlEDRRERLQQEIEELLKKLEEAE--LKELQAELEELEEELEELQEELERL 459

                           90       100       110       120
                   ....*....|....*....|....*....|....*....|.
gi 18418089    183 WRLLELRKKQFALLLHVVDELQETMEDEQ--KSMVEEMQRN 221
Cdd:TIGR02168  460 EEALEELREELEEAEQALDAAERELAQLQarLDSLERLQEN 500
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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