|
Name |
Accession |
Description |
Interval |
E-value |
| PLN02287 |
PLN02287 |
3-ketoacyl-CoA thiolase |
1-457 |
0e+00 |
|
3-ketoacyl-CoA thiolase
Pssm-ID: 215161 [Multi-domain] Cd Length: 452 Bit Score: 851.75 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 1 MERAMERQKILLRHLNPVSSsnsslkhEPSLLSPVNCVSEVSP----MAAFGDDIVIVAAYRTAICKARRGGFKDTLPDD 76
Cdd:PLN02287 1 MEKAINRQRVLLRHLRPSSS-------EPSSLSASACAAGDSAayhrTTAFGDDVVIVAAYRTPICKAKRGGFKDTYPDD 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 77 LLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVRTVNRQCSSGLQAVADVAASIRAGYY 156
Cdd:PLN02287 74 LLAPVLKAVVEKTGLNPSEVGDIVVGTVLAPGSQRANECRMAAFYAGFPETVPVRTVNRQCSSGLQAVADVAAAIKAGFY 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 157 DIGIGAGVESMSTDHIPGGGfhGSNPRAQDFPKARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLK 236
Cdd:PLN02287 154 DIGIGAGVESMTTNPMAWEG--GVNPRVESFSQAQDCLLPMGITSENVAERFGVTREEQDQAAVESHRKAAAATASGKFK 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 237 DEIIPVATKIVDPETKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLP 316
Cdd:PLN02287 232 DEIVPVHTKIVDPKTGEEKPIVISVDDGIRPNTTLADLAKLKPVFKKNGTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLP 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 317 ILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPL 396
Cdd:PLN02287 312 ILGVFRSFAAVGVDPAVMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQFVYCCKKLGLDPEKVNVNGGAIALGHPL 391
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30695564 397 GATGARCVATLLHEMKRRGKDCRFGVISMCIGTGMGAAAVFERGDSVDNLSNARVANGDSH 457
Cdd:PLN02287 392 GATGARCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFERGDSVDELSNARKVEGNNL 452
|
|
| thiolase |
cd00751 |
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of ... |
52-439 |
0e+00 |
|
Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and eukaryotes (cytosol, microbodies and mitochondria). There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238383 [Multi-domain] Cd Length: 386 Bit Score: 528.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMeCRVAAYFAGFPDSVPVR 131
Cdd:cd00751 1 VIVSAVRTPIGRFG-GALKDVSADDLGAAVIKALLERAGLDPEEVDDVIMGNVLQAGEGQNP-ARQAALLAGLPESVPAT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDHI--------PGGGFHGSNPRAQDFPKARDCLLPMGITSEN 203
Cdd:cd00751 79 TVNRVCGSGLQAVALAAQSIAAGEADVVVAGGVESMSRAPYllpkarrgGRLGLNTLDGMLDDGLTDPFTGLSMGITAEN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 204 VAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpetKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQ 283
Cdd:cd00751 159 VAEKYGISREEQDEFALRSHQRAAAAQEAGRFKDEIVPVEVP------GRKGPVVVDRDEGPRPDTTLEKLAKLKPAFKK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 284 NGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINE 363
Cdd:cd00751 233 DGTVTAGNASGINDGAAAVLLMSEEKAKELGLKPLARIVGYAVAGVDPAIMGIGPVPAIPKALKRAGLTLDDIDLIEINE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30695564 364 AFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:cd00751 313 AFAAQALACLKELGLDPEKVNVNGGAIALGHPLGASGARIVVTLLHELKRRGG--RYGLATMCIGGGQGAAMVIER 386
|
|
| PaaJ |
COG0183 |
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is ... |
49-439 |
1.35e-173 |
|
Acetyl-CoA acetyltransferase [Lipid transport and metabolism]; Acetyl-CoA acetyltransferase is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 439953 [Multi-domain] Cd Length: 391 Bit Score: 491.89 E-value: 1.35e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 49 DDIVIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMeCRVAAYFAGFPDSV 128
Cdd:COG0183 2 REVVIVDAVRTPFGRFG-GALADVRADDLGAAVIKALLERAGLDPEAVDDVILGCVLQAGQGQNP-ARQAALLAGLPESV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIPGGGFHGS-----NPRAQDfPKARDCL------LPM 197
Cdd:COG0183 80 PAVTVNRVCGSGLQAVALAAQAIAAGDADVVIAGGVESMS--RAPMLLPKARwgyrmNAKLVD-PMINPGLtdpytgLSM 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 198 GITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpetKAEKAIVVSVDDGVRPNSNMADLAKL 277
Cdd:COG0183 157 GETAENVAERYGISREEQDAFALRSHQRAAAAIAAGRFDDEIVPVEVP------DRKGEVVVDRDEGPRPDTTLEKLAKL 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 278 KTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDID 357
Cdd:COG0183 231 KPAFKKDGTVTAGNASGINDGAAALLLMSEEAAKELGLKPLARIVAYAVAGVDPEIMGIGPVPATRKALARAGLTLDDID 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 358 LFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVF 437
Cdd:COG0183 311 LIEINEAFAAQVLAVLRELGLDPDKVNVNGGAIALGHPLGASGARILVTLLHELERRGG--RYGLATMCIGGGQGIALII 388
|
..
gi 30695564 438 ER 439
Cdd:COG0183 389 ER 390
|
|
| AcCoA-C-Actrans |
TIGR01930 |
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze ... |
53-438 |
3.30e-171 |
|
acetyl-CoA acetyltransferases; This model represents a large family of enzymes which catalyze the thiolysis of a linear fatty acid CoA (or acetoacetyl-CoA) using a second CoA molecule to produce acetyl-CoA and a CoA-ester product two carbons shorter (or, alternatively, the condensation of two molecules of acetyl-CoA to produce acetoacetyl-CoA and CoA). This enzyme is also known as "thiolase", "3-ketoacyl-CoA thiolase", "beta-ketothiolase" and "Fatty oxidation complex beta subunit". When catalyzing the degradative reaction on fatty acids the corresponding EC number is 2.3.1.16. The condensation reaction corresponds to 2.3.1.9. Note that the enzymes which catalyze the condensation are generally not involved in fatty acid biosynthesis, which is carried out by a decarboxylating condensation of acetyl and malonyl esters of acyl carrier proteins. Rather, this activity may produce acetoacetyl-CoA for pathways such as IPP biosynthesis in the absence of sufficient fatty acid oxidation. [Fatty acid and phospholipid metabolism, Other]
Pssm-ID: 273881 [Multi-domain] Cd Length: 385 Bit Score: 485.96 E-value: 3.30e-171
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 53 IVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQrAMECRVAAYFAGFPDSVPVRT 132
Cdd:TIGR01930 1 IVAAARTPIGKFG-GSLKDVSAEDLGAAVIKELLERNPLDPELIDDVIFGNVLQAGEQ-QNIARQAALLAGLPESVPAYT 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 133 VNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMST------DHIPGGGFHGSNPRAQDFPKAR---DCLLPMGITSEN 203
Cdd:TIGR01930 79 VNRQCASGLQAVILAAQLIRAGEADVVVAGGVESMSRvpygvpRSLRWGVKPGNAELEDARLKDLtdaNTGLPMGVTAEN 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 204 VAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpetKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQ 283
Cdd:TIGR01930 159 LAKKYGISREEQDEYALRSHQRAAKAWEEGLFKDEIVPVTVK------GRKGPVTVSSDEGIRPNTTLEKLAKLKPAFDP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 284 NGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINE 363
Cdd:TIGR01930 233 DGTVTAGNSSPLNDGAAALLLMSEEKAKELGLTPLARIVSFAVAGVDPEIMGLGPVPAIPKALKKAGLSISDIDLFEINE 312
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 30695564 364 AFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFE 438
Cdd:TIGR01930 313 AFAAQVLACIKELGLDLEKVNVNGGAIALGHPLGASGARIVTTLLHELKRRGG--RYGLATMCIGGGQGAAVILE 385
|
|
| PRK05790 |
PRK05790 |
putative acyltransferase; Provisional |
49-439 |
3.05e-146 |
|
putative acyltransferase; Provisional
Pssm-ID: 180261 [Multi-domain] Cd Length: 393 Bit Score: 422.64 E-value: 3.05e-146
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 49 DDIVIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRaMECRVAAYFAGFPDSV 128
Cdd:PRK05790 2 KDVVIVSAARTPIGKFG-GALKDVSAVELGAIVIKAALERAGVPPEQVDEVIMGQVLQAGAGQ-NPARQAALKAGLPVEV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMST-DHI---PGGGFHGSNPRAQDfPKARDCL------LPMG 198
Cdd:PRK05790 80 PALTINKVCGSGLKAVALAAQAIRAGDADIVVAGGQESMSQaPHVlpgSRWGQKMGDVELVD-TMIHDGLtdafngYHMG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 199 ITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpeTKAEKAIVVSVDDGVRPNSNMADLAKLK 278
Cdd:PRK05790 159 ITAENLAEQYGITREEQDEFALASQQKAEAAIKAGRFKDEIVPVTIK-----QRKGDPVVVDTDEHPRPDTTAESLAKLR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 279 TVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDL 358
Cdd:PRK05790 234 PAFDKDGTVTAGNASGINDGAAAVVVMSEAKAKELGLTPLARIVSYAVAGVDPAIMGIGPVPAIRKALEKAGWSLADLDL 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 359 FEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFE 438
Cdd:PRK05790 314 IEINEAFAAQALAVEKELGLDPEKVNVNGGAIALGHPIGASGARILVTLLHEMKRRGA--KKGLATLCIGGGQGVALIVE 391
|
.
gi 30695564 439 R 439
Cdd:PRK05790 392 R 392
|
|
| PRK09052 |
PRK09052 |
acetyl-CoA C-acyltransferase; |
50-439 |
1.02e-145 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 181626 [Multi-domain] Cd Length: 399 Bit Score: 421.72 E-value: 1.02e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERT-SLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSV 128
Cdd:PRK09052 7 DAYIVAATRTPVGKAPRGMFKNTRPDDLLAHVLRSAVAQVpGLDPKLIEDAIVGCAMPEAEQGLNVARIGALLAGLPNSV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTdhIPGGGFHGS-NPRAQDFPKARDCLLPMGITSENVAER 207
Cdd:PRK09052 87 GGVTVNRFCASGLQAVAMAADRIRVGEADVMIAAGVESMSM--VPMMGNKPSmSPAIFARDENVGIAYGMGLTAEKVAEQ 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 208 FGVTREEQDMAAVESHKRAAAAIASGKLKDEIIP--VATKIVDPETKA--EKAIVVSVDDGVRPNSNMADLAKLKTVFKQ 283
Cdd:PRK09052 165 WKVSREDQDAFALESHQKAIAAQQAGEFKDEITPyeITERFPDLATGEvdVKTRTVDLDEGPRADTSLEGLAKLKPVFAN 244
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 284 NGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINE 363
Cdd:PRK09052 245 KGSVTAGNSSQTSDGAGAVILVSEKALKQFNLTPLARFVSFAVAGVPPEIMGIGPIEAIPAALKQAGLKQDDLDWIELNE 324
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 30695564 364 AFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:PRK09052 325 AFAAQSLAVIRDLGLDPSKVNPLGGAIALGHPLGATGAIRTATVVHGLRRTNL--KYGMVTMCVGTGMGAAGIFER 398
|
|
| PRK07661 |
PRK07661 |
acetyl-CoA C-acetyltransferase; |
52-439 |
6.32e-145 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181072 [Multi-domain] Cd Length: 391 Bit Score: 419.16 E-value: 6.32e-145
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVR 131
Cdd:PRK07661 5 VIVAGARTPVGKAKKGSLKTVRPDDLGALVVKETLKRAGNYEGPIDDLIIGCAMPEAEQGLNMARNIGALAGLPYTVPAI 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTdhIPGGGfHGSNPRAQDFPKARDCLLPMGITSENVAERFGVT 211
Cdd:PRK07661 85 TINRYCSSGLQSIAYGAERIMLGHSEAVIAGGAESMSL--VPMMG-HVVRPNPRLVEAAPEYYMGMGHTAEQVAVKYGIS 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 212 REEQDMAAVESHKRAAAAIASGKLKDEIIP--VATKIVDPETK-AEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTT 288
Cdd:PRK07661 162 REDQDAFAVRSHQRAAKALAEGKFADEIVPvdVTLRTVGENNKlQEETITFSQDEGVRADTTLEILGKLRPAFNVKGSVT 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 289 AGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQ 368
Cdd:PRK07661 242 AGNSSQMSDGAAAVLLMDREKAESDGLKPLAKFRSFAVAGVPPEVMGIGPIAAIPKALKLAGLELSDIGLFELNEAFASQ 321
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 30695564 369 YVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:PRK07661 322 SIQVIRELGLDEEKVNVNGGAIALGHPLGCTGAKLTLSLIHEMKRRNE--QFGIVTMCIGGGMGAAGVFEL 390
|
|
| PRK09051 |
PRK09051 |
beta-ketothiolase BktB; |
50-439 |
3.97e-123 |
|
beta-ketothiolase BktB;
Pssm-ID: 181625 [Multi-domain] Cd Length: 394 Bit Score: 363.90 E-value: 3.97e-123
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckarrGGF----KDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFP 125
Cdd:PRK09051 4 EVVVVSGVRTAI-----GTFggslKDVAPTDLGATVVREALARAGVDPDQVGHVVFGHVIPTEPRDMYLSRVAAINAGVP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 126 DSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMS-TDHIPGGGFHGSnpRAQDFpKARDCLL--------- 195
Cdd:PRK09051 79 QETPAFNVNRLCGSGLQAIVSAAQAILLGDADVAIGGGAESMSrAPYLLPAARWGA--RMGDA-KLVDMMVgalhdpfgt 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 196 -PMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVatkivdpETKAEKAIVV-SVDDGVRPNSNMAD 273
Cdd:PRK09051 156 iHMGVTAENVAAKYGISREAQDALALESHRRAAAAIAAGYFKDQIVPV-------EIKTRKGEVVfDTDEHVRADTTLED 228
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 274 LAKLKTVFKQ-NGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLN 352
Cdd:PRK09051 229 LAKLKPVFKKeNGTVTAGNASGINDGAAAVVLAEADAAEARGLKPLARLVGYAHAGVDPEYMGIGPVPATQKALERAGLT 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 353 VSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMG 432
Cdd:PRK09051 309 VADLDVIEANEAFAAQACAVTRELGLDPAKVNPNGSGISLGHPVGATGAIITVKALYELQRIGG--RYALVTMCIGGGQG 386
|
....*..
gi 30695564 433 AAAVFER 439
Cdd:PRK09051 387 IAAIFER 393
|
|
| PRK06205 |
PRK06205 |
acetyl-CoA C-acetyltransferase; |
50-439 |
4.46e-112 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235741 [Multi-domain] Cd Length: 404 Bit Score: 335.80 E-value: 4.46e-112
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckARRGG-FKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMEcRVAAYFAGFPDSV 128
Cdd:PRK06205 3 DAVICEPVRTPV--GRFGGaFKDVPAEELAATVIRALVERTGIDPARIDDVIFGQGYPNGEAPAIG-RVAALDAGLPVTV 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMS------TDH---IPGGG--FHGSNPRAQDFPKARDCLLPM 197
Cdd:PRK06205 80 PGMQLDRRCGSGLQAVITAAMQVQTGAADVVIAGGAESMSnvefytTDMrwgVRGGGvqLHDRLARGRETAGGRRFPVPG 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 198 GI--TSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdPETKAEkAIVVSVDDGVRPNSNMADLA 275
Cdd:PRK06205 160 GMieTAENLRREYGISREEQDALAVRSHQRAVAAQEAGRFDDEIVPVTV----PQRKGD-PTVVDRDEHPRADTTLESLA 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 276 KLKTVFKQ---NGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLN 352
Cdd:PRK06205 235 KLRPIMGKqdpEATVTAGNASGQNDAAAACLVTTEDKAEELGLRPLARLVSWAVAGVEPSRMGIGPVPATEKALARAGLT 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 353 VSDIDLFEINEAFASQyVYSCKK----LELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRgkDCRFGVISMCIG 428
Cdd:PRK06205 315 LDDIDLIELNEAFAAQ-VLAVLKewgfGADDEERLNVNGSGISLGHPVGATGGRILATLLRELQRR--QARYGLETMCIG 391
|
410
....*....|.
gi 30695564 429 TGMGAAAVFER 439
Cdd:PRK06205 392 GGQGLAAVFER 402
|
|
| PRK07108 |
PRK07108 |
acetyl-CoA C-acyltransferase; |
50-438 |
1.30e-111 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180843 [Multi-domain] Cd Length: 392 Bit Score: 334.43 E-value: 1.30e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVP 129
Cdd:PRK07108 3 EAVIVSTARTPLAKSWRGAFNMTHGATLGGHVVQHAVERAKLDPAEVEDVIMGCANPEGATGANIARQIALRAGLPVTVP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 130 VRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVES-------MSTDHIPGGGFHGSNPraqdfpkarDCLLPMGITSE 202
Cdd:PRK07108 83 GMTVNRFCSSGLQTIALAAQRVIAGEGDVFVAGGVESiscvqneMNRHMLREGWLVEHKP---------EIYWSMLQTAE 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 203 NVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIP--VATKIVDPETKA--EKAIVVSVDDGVRPNSNMADLAKLK 278
Cdd:PRK07108 154 NVAKRYGISKERQDEYGVQSQQRAAAAQAAGRFDDEIVPitVTAGVADKATGRlfTKEVTVSADEGIRPDTTLEGVSKIR 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 279 TVFkQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDL 358
Cdd:PRK07108 234 SAL-PGGVITAGNASQFSDGASACVVMNAKVAEREGLQPLGIFRGFAVAGCEPDEMGIGPVFAVPKLLKQAGLKVDDIDL 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 359 FEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGkdCRFGVISMCIGTGMGAAAVFE 438
Cdd:PRK07108 313 WELNEAFAVQVLYCRDTLGIPMDRLNVNGGAIAVGHPYGVSGARLTGHALIEGKRRG--AKYVVVTMCIGGGQGAAGLFE 390
|
|
| PRK06445 |
PRK06445 |
acetyl-CoA C-acetyltransferase; |
49-439 |
9.45e-111 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180563 [Multi-domain] Cd Length: 394 Bit Score: 332.07 E-value: 9.45e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 49 DDIVIVAAYRTAICKAR-----RGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAG 123
Cdd:PRK06445 2 EDVYLVDFARTAFSRFRpkdpqKDVFNNIRPEELAAMLINRLIEKTGIKPEEIDDIITGCALQVGENWLYGGRHPIFLAR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 124 FPDSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIPGGG--FHGSNPRAQDFPKARDCLLP----M 197
Cdd:PRK06445 82 LPYNIPAMAVDRQCASSLTTVSIGAMEIATGMADIVIAGGVEHMT--RTPMGDnpHIEPNPKLLTDPKYIEYDLTtgyvM 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 198 GITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdpETKAEKaIVVSVDDGVRPNSNMADLAKL 277
Cdd:PRK06445 160 GLTAEKLAEEAGIKREEMDRWSLRSHQLAAKAIQEGYFKDEILPIEV-----EVEGKK-KVVDVDQSVRPDTSLEKLAKL 233
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 278 KTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDID 357
Cdd:PRK06445 234 PPAFKPDGVITAGNSSPLNSGASYVLLMSKKAVKKYGLKPMAKIRSFGFAGVPPAIMGKGPVPASKKALEKAGLSVKDID 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 358 LFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDcrFGVISMCIGTGMGAAAVF 437
Cdd:PRK06445 314 LWEINEAFAVVVLYAIKELGLDPETVNIKGGAIAIGHPLGATGARIVGTLARQLQIKGKD--YGVATLCVGGGQGGAVVL 391
|
..
gi 30695564 438 ER 439
Cdd:PRK06445 392 ER 393
|
|
| fadA |
PRK08947 |
3-ketoacyl-CoA thiolase; Reviewed |
50-439 |
4.00e-108 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181592 [Multi-domain] Cd Length: 387 Bit Score: 325.38 E-value: 4.00e-108
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERT-SLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSV 128
Cdd:PRK08947 3 DVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNpALDPAEIDDIIWGCVQQTLEQGFNIARNAALLAGIPHSV 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIP---GGGFHGSNprAQDFPKARDCllpMGITSENVA 205
Cdd:PRK08947 83 PAVTVNRLCGSSMQALHDAARAIMTGDGDVFLIGGVEHMG--HVPmnhGVDFHPGL--SKNVAKAAGM---MGLTAEMLG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 206 ERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETKaekaiVVSVDDGVRPNSNMADLAKLKTVFK-QN 284
Cdd:PRK08947 156 KMHGISREQQDAFAARSHQRAWAATQEGRFKNEIIPTEGHDADGVLK-----LFDYDEVIRPETTVEALAALRPAFDpVN 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 285 GSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEA 364
Cdd:PRK08947 231 GTVTAGTSSALSDGASAMLVMSESRAKELGLKPRARIRSMAVAGCDPSIMGYGPVPATQKALKRAGLSISDIDVFELNEA 310
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30695564 365 FASQYVYSCKKLEL-DM--EKVNVNGGAIAIGHPLGATGARCVATLLHEMKRrgKDCRFGVISMCIGTGMGAAAVFER 439
Cdd:PRK08947 311 FAAQSLPCLKDLGLlDKmdEKVNLNGGAIALGHPLGCSGARISTTLLNLMER--KDAQFGLATMCIGLGQGIATVFER 386
|
|
| PRK07851 |
PRK07851 |
acetyl-CoA C-acetyltransferase; |
52-439 |
1.11e-104 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181146 [Multi-domain] Cd Length: 406 Bit Score: 316.94 E-value: 1.11e-104
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKARRGGFKDTLPDDLLASVLKAVVERT-SLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFpDSVPV 130
Cdd:PRK07851 5 VIVSTARSPIGRAFKGSLKDMRPDDLAAQMVRAALDKVpALDPTDIDDLMLGCGLPGGEQGFNMARVVAVLLGY-DFLPG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 131 RTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMS------TDHIP-------------------GGGFHGSNPRAQ 185
Cdd:PRK07851 84 TTVNRYCSSSLQTTRMAFHAIKAGEGDVFISAGVETVSrfakgnSDSLPdtknplfaeaqartaaraeGGAEAWHDPRED 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 186 DfpKARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpetkaeKAIVVSVDDGV 265
Cdd:PRK07851 164 G--LLPDVYIAMGQTAENVAQLTGISREEQDEWGVRSQNRAEEAIANGFFEREITPVTLP---------DGTVVSTDDGP 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 266 RPNSNMADLAKLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAA 345
Cdd:PRK07851 233 RAGTTYEKVSQLKPVFRPDGTVTAGNACPLNDGAAAVVIMSDTKARELGLTPLARIVSTGVSGLSPEIMGLGPVEASKQA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 346 TKLAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISM 425
Cdd:PRK07851 313 LARAGMSIDDIDLVEINEAFAAQVLPSARELGIDEDKLNVSGGAIALGHPFGMTGARITTTLLNNLQTHDK--TFGLETM 390
|
410
....*....|....
gi 30695564 426 CIGTGMGAAAVFER 439
Cdd:PRK07851 391 CVGGGQGMAMVLER 404
|
|
| PRK09050 |
PRK09050 |
beta-ketoadipyl CoA thiolase; Validated |
50-439 |
6.36e-100 |
|
beta-ketoadipyl CoA thiolase; Validated
Pssm-ID: 181624 [Multi-domain] Cd Length: 401 Bit Score: 304.57 E-value: 6.36e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckARRGG-FKDTLPDDLLASVLKAVVERT-SLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDS 127
Cdd:PRK09050 3 EAFICDAIRTPI--GRYGGaLSSVRADDLGAVPLKALMARNpGVDWEAVDDVIYGCANQAGEDNRNVARMSALLAGLPVS 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 128 VPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMST-------------------DHIPGGGFhgSNPRAqdfp 188
Cdd:PRK09050 81 VPGTTINRLCGSGMDAVGTAARAIKAGEAELMIAGGVESMSRapfvmgkadsafsrqaeifDTTIGWRF--VNPLM---- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 189 KARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdPETKAEkAIVVSVDDGVRPN 268
Cdd:PRK09050 155 KAQYGVDSMPETAENVAEDYNISRADQDAFALRSQQRAAAAQAAGFLAEEIVPVTI----PQKKGD-PVVVDRDEHPRPE 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 269 SNMADLAKLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLP----ILGvfrsFAVTGVEPSVMGIGPAVAIPA 344
Cdd:PRK09050 230 TTLEALAKLKPVFRPDGTVTAGNASGVNDGAAALLLASEAAAKKHGLTprarILG----MATAGVEPRIMGIGPAPATRK 305
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 345 ATKLAGLNVSDIDLFEINEAFASQYVYSCKKLEL--DMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGV 422
Cdd:PRK09050 306 LLARLGLTIDQFDVIELNEAFAAQGLAVLRQLGLadDDARVNPNGGAIALGHPLGMSGARLVLTALHQLERTGG--RYAL 383
|
410
....*....|....*..
gi 30695564 423 ISMCIGTGMGAAAVFER 439
Cdd:PRK09050 384 CTMCIGVGQGIALAIER 400
|
|
| PRK05656 |
PRK05656 |
acetyl-CoA C-acetyltransferase; |
50-440 |
2.04e-96 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168156 Cd Length: 393 Bit Score: 295.64 E-value: 2.04e-96
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckarrGGFKDTLPD----DLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAmECRVAAYFAGFP 125
Cdd:PRK05656 3 DVVIVAATRTAI-----GSFQGSLANipavELGAAVIRRLLEQTGLDPAQVDEVILGQVLTAGAGQN-PARQAAIKAGLP 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 126 DSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDH--IPGG--GFHGSNPRAQDfPKARDCLLP----- 196
Cdd:PRK05656 77 HSVPAMTLNKVCGSGLKALHLAAQAIRCGDAEVIIAGGQENMSLAPyvLPGArtGLRMGHAQLVD-SMITDGLWDafndy 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 197 -MGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPvatkIVDPETKAEkAIVVSVDDGVRPNSNMADLA 275
Cdd:PRK05656 156 hMGITAENLVEKYGISREAQDAFAAASQQKAVAAIEAGRFDDEITP----ILIPQRKGE-PLAFATDEQPRAGTTAESLA 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 276 KLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSD 355
Cdd:PRK05656 231 KLKPAFKKDGSVTAGNASSLNDGAAAVLLMSAAKAKALGLPVLAKIAAYANAGVDPAIMGIGPVSATRRCLDKAGWSLAE 310
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 356 IDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRgkDCRFGVISMCIGTGMGAAA 435
Cdd:PRK05656 311 LDLIEANEAFAAQSLAVGKELGWDAAKVNVNGGAIALGHPIGASGCRVLVTLLHEMIRR--DAKKGLATLCIGGGQGVAL 388
|
....*
gi 30695564 436 VFERG 440
Cdd:PRK05656 389 AIERD 393
|
|
| PRK08242 |
PRK08242 |
acetyl-CoA C-acetyltransferase; |
53-439 |
6.41e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236197 [Multi-domain] Cd Length: 402 Bit Score: 291.79 E-value: 6.41e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 53 IVAAYRTAICKARRGG-FKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVR 131
Cdd:PRK08242 6 IYDAVRTPRGKGKKDGsLHEVKPVRLAAGLLEALRDRNGLDTAAVDDVVLGCVTPVGDQGADIARTAVLAAGLPETVPGV 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIP---GGGFHGSNPRAQdfpkARDCLLPMGITSENVAERF 208
Cdd:PRK08242 86 QINRFCASGLEAVNLAAAKVRSGWDDLVIAGGVESMS--RVPmgsDGGAWAMDPSTN----FPTYFVPQGISADLIATKY 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 209 GVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVatkivdpeTKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGST- 287
Cdd:PRK08242 160 GFSREDVDAYAVESQQRAAAAWAEGYFAKSVVPV--------KDQNGLTILDHDEHMRPGTTMESLAKLKPSFAMMGEMg 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 288 --------------------TAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATK 347
Cdd:PRK08242 232 gfdavalqkypeverinhvhHAGNSSGIVDGAAAVLIGSEEAGKALGLKPRARIVATATIGSDPTIMLTGPVPATRKALA 311
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 348 LAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCI 427
Cdd:PRK08242 312 KAGLTVDDIDLFELNEAFASVVLRFMQALDIPHDKVNVNGGAIAMGHPLGATGAMILGTVLDELERRGK--RTALITLCV 389
|
410
....*....|..
gi 30695564 428 GTGMGAAAVFER 439
Cdd:PRK08242 390 GGGMGIATIIER 401
|
|
| PRK08235 |
PRK08235 |
acetyl-CoA C-acetyltransferase; |
52-438 |
8.19e-95 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181311 [Multi-domain] Cd Length: 393 Bit Score: 291.23 E-value: 8.19e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGsQRAMECRVAAYFAGFPDSVPVR 131
Cdd:PRK08235 5 VIVSAARTPFGKFG-GSLKDVKATELGGIAIKEALERANVSAEDVEEVIMGTVLQGG-QGQIPSRQAARAAGIPWEVQTE 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTD--HIPGG--GFHGSNPRAQDFpKARDCL------LPMGITS 201
Cdd:PRK08235 83 TVNKVCASGLRAVTLADQIIRAGDASVIVAGGMESMSNApyILPGArwGYRMGDNEVIDL-MVADGLtcafsgVHMGVYG 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 202 ENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdPETKAEKaIVVSVDDGVRPNSNMADLAKLKTVF 281
Cdd:PRK08235 162 GEVAKELGISREAQDEWAYRSHQRAVSAHEEGRFEEEIVPVTI----PQRKGDP-IVVAKDEAPRKDTTIEKLAKLKPVF 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 282 KQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEI 361
Cdd:PRK08235 237 DKTGTITAGNAPGVNDGAAALVLMSEDRAKQEGRKPLATILAHTAIAVEAKDFPRTPGYAINALLEKTGKTVEDIDLFEI 316
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 30695564 362 NEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDcrFGVISMCIGTGMGAAAVFE 438
Cdd:PRK08235 317 NEAFAAVALASTEIAGIDPEKVNVNGGAVALGHPIGASGARIIVTLIHELKRRGGG--IGIAAICSGGGQGDAVLIE 391
|
|
| PRK07850 |
PRK07850 |
steroid 3-ketoacyl-CoA thiolase; |
52-439 |
9.35e-93 |
|
steroid 3-ketoacyl-CoA thiolase;
Pssm-ID: 181145 [Multi-domain] Cd Length: 387 Bit Score: 285.85 E-value: 9.35e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKaRRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVR 131
Cdd:PRK07850 5 VIVEAVRTPIGK-RNGWLSGLHAAELLGAVQRAVLDRAGIDPGDVEQVIGGCVTQAGEQSNNITRTAWLHAGLPYHVGAT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIPGG---GFHGSNPRAQDFpkarDCLLPMGITS-ENVAER 207
Cdd:PRK07850 84 TIDCQCGSAQQANHLVAGLIAAGAIDVGIACGVEAMS--RVPLGanaGPGRGLPRPDSW----DIDMPNQFEAaERIAKR 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 208 FGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETKAEKAI-VVSVDDGVRpNSNMADLAKLKTVFKqNGS 286
Cdd:PRK07850 158 RGITREDVDAFGLRSQRRAAQAWAEGRFDREISPVQAPVLDEEGQPTGETrLVTRDQGLR-DTTMEGLAGLKPVLE-GGI 235
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 287 TTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFA 366
Cdd:PRK07850 236 HTAGTSSQISDGAAAVLWMDEDRARALGLRPRARIVAQALVGAEPYYHLDGPVQATAKVLEKAGMKIGDIDLVEINEAFA 315
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30695564 367 SQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:PRK07850 316 SVVLSWAQVHEPDMDKVNVNGGAIALGHPVGSTGARLITTALHELERTDK--STALITMCAGGALSTGTIIER 386
|
|
| PRK06633 |
PRK06633 |
acetyl-CoA C-acetyltransferase; |
72-438 |
1.97e-90 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 168632 [Multi-domain] Cd Length: 392 Bit Score: 279.99 E-value: 1.97e-90
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 72 TLPDDLLAS-VLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAmECRVAAYFAGFPDSVPVRTVNRQCSSGLQAVADVAAS 150
Cdd:PRK06633 24 TTPAPMLAAhLIKDILQNSKIDPALVNEVILGQVITGGSGQN-PARQTLIHAGIPKEVPGYTINKVCGSGLKSVALAANS 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 151 IRAGYYDIGIGAGVESMSTdhipggGFHGSNPRA-QDFPKAR-------DCLLP------MGITSENVAERFGVTREEQD 216
Cdd:PRK06633 103 IMTGDNEIVIAGGQENMSL------GMHGSYIRAgAKFGDIKmvdlmqyDGLTDvfsgvfMGITAENISKQFNISRQEQD 176
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 217 MAAVESHKRAAAAIASGKLKDEIIPVATKIvdpetkAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTTAGNASQIS 296
Cdd:PRK06633 177 EFALSSHKKAAKAQLAGIFKDEILPIEVTI------KKTTSLFDHDETVRPDTSLEILSKLRPAFDKNGVVTAGNASSIN 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 297 DGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYVYSCKKL 376
Cdd:PRK06633 251 DGAACLMVVSEEALKKHNLTPLARIVSYASAGVDPSIMGTAPVPASQKALSKAGWSVNDLEVIEVNEAFAAQSIYVNREM 330
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30695564 377 ELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMkRRGKdCRFGVISMCIGTGMGAAAVFE 438
Cdd:PRK06633 331 KWDMEKVNINGGAIAIGHPIGASGGRVLITLIHGL-RRAK-AKKGLVTLCIGGGMGMAMCVE 390
|
|
| fadI |
PRK08963 |
3-ketoacyl-CoA thiolase; Reviewed |
48-439 |
2.13e-88 |
|
3-ketoacyl-CoA thiolase; Reviewed
Pssm-ID: 181597 [Multi-domain] Cd Length: 428 Bit Score: 276.09 E-value: 2.13e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 48 GDDIVIVAAYRTAICKARRGgFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVI----APGSQRAMECRvaayfAG 123
Cdd:PRK08963 4 GDRIAIVSGLRTPFAKQATA-FHGIPAVDLGKMVVGELLARSEIDPELIEQLVFGQVVqmpeAPNIAREIVLG-----TG 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 124 FPDSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDHIPGggfhgSNPRAQ---DFPKARDC------- 193
Cdd:PRK08963 78 MNVHTDAYSVSRACATSFQAVANVAESIMAGTIDIGIAGGADSSSVLPIGV-----SKKLARalvDLNKARTLgqrlklf 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 194 -------LLP-------------MGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEiipVATKIVDPETKA 253
Cdd:PRK08963 153 srlrlrdLLPvppavaeystglrMGDTAEQMAKTYGISREEQDALAHRSHQLAAQAWAEGKLDDE---VMTAHVPPYKQP 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 254 ekaivVSVDDGVRPNSNMADLAKLKTVF-KQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEP- 331
Cdd:PRK08963 230 -----LEEDNNIRGDSTLEDYAKLRPAFdRKHGTVTAANSTPLTDGAAAVLLMSESRAKALGLTPLGYLRSYAFAAIDVw 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 332 SVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYV----------YSCKKL-------ELDMEKVNVNGGAIAIGH 394
Cdd:PRK08963 305 QDMLLGPAYATPLALERAGLTLADLTLIDMHEAFAAQTLanlqmfaserFAREKLgrsqaigEVDMSKFNVLGGSIAYGH 384
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 30695564 395 PLGATGARCVATLLHEMKRRGKDcrFGVISMCIGTGMGAAAVFER 439
Cdd:PRK08963 385 PFAATGARMITQTLHELRRRGGG--LGLTTACAAGGLGAAMVLEV 427
|
|
| PRK07801 |
PRK07801 |
acetyl-CoA C-acetyltransferase; |
53-439 |
5.48e-88 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181123 [Multi-domain] Cd Length: 382 Bit Score: 273.51 E-value: 5.48e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 53 IVAAYRTAICKaRRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVRT 132
Cdd:PRK07801 6 IVDAVRTPVGK-RKGGLAGVHPADLGAHVLKGLVDRTGIDPAAVDDVIFGCVDTIGPQAGNIARTSWLAAGLPEEVPGVT 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 133 VNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIPGGGfhgsnpraqdfpkARDCLLPMGITS----------- 201
Cdd:PRK07801 85 VDRQCGSSQQAIHFAAQAVMSGTQDLVVAGGVQNMS--QIPISS-------------AMTAGEQLGFTSpfaeskgwlhr 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 202 ------------ENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdpetkaekaivVSVDDGVRpNS 269
Cdd:PRK07801 150 ygdqevsqfrgaELIAEKWGISREEMERFALESHRRAFAAIRAGRFDNEIVPVGG--------------VTVDEGPR-ET 214
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 270 NMADLAKLKTVFkQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLA 349
Cdd:PRK07801 215 SLEKMAGLKPLV-EGGRLTAAVASQISDGASAVLLASERAVKRHGLTPRARIHHLSVRGDDPVFMLTAPIPATRYALEKT 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 350 GLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGT 429
Cdd:PRK07801 294 GLSIDDIDVVEINEAFAPVVLAWLKETGADPAKVNPNGGAIALGHPLGATGAKLMTTLLHELERTGG--RYGLQTMCEGG 371
|
410
....*....|
gi 30695564 430 GMGAAAVFER 439
Cdd:PRK07801 372 GTANVTIIER 381
|
|
| PLN02644 |
PLN02644 |
acetyl-CoA C-acetyltransferase |
50-439 |
9.13e-88 |
|
acetyl-CoA C-acetyltransferase
Pssm-ID: 215347 [Multi-domain] Cd Length: 394 Bit Score: 273.12 E-value: 9.13e-88
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckarrGGFKDTLPD----DLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAmECRVAAYFAGFP 125
Cdd:PLN02644 2 DVCIVGVARTPI-----GGFLGSLSSlsatELGSIAIQAALERAGVDPALVQEVFFGNVLSANLGQA-PARQAALGAGLP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 126 DSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMS-TDHIPGGGFHGSnpRAQDfPKARDCLL--------- 195
Cdd:PLN02644 76 PSTICTTVNKVCASGMKAVMLAAQSIQLGINDVVVAGGMESMSnAPKYLPEARKGS--RLGH-DTVVDGMLkdglwdvyn 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 196 --PMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdPETKAEKAIVVSVDDGvrPNS-NMA 272
Cdd:PLN02644 153 dfGMGVCAELCADQYSISREEQDAYAIQSYERAIAAQEAGAFAWEIVPVEV----PGGRGRPSVIVDKDEG--LGKfDPA 226
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 273 DLAKLKTVFKQN-GSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGL 351
Cdd:PLN02644 227 KLRKLRPSFKEDgGSVTAGNASSISDGAAALVLVSGEKALELGLQVIAKIRGYADAAQAPELFTTAPALAIPKALKHAGL 306
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 352 NVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGM 431
Cdd:PLN02644 307 EASQVDYYEINEAFSVVALANQKLLGLDPEKVNVHGGAVSLGHPIGCSGARILVTLLGVLRSKNG--KYGVAGICNGGGG 384
|
....*...
gi 30695564 432 GAAAVFER 439
Cdd:PLN02644 385 ASAIVVEL 392
|
|
| PRK08131 |
PRK08131 |
3-oxoadipyl-CoA thiolase; |
50-439 |
1.51e-86 |
|
3-oxoadipyl-CoA thiolase;
Pssm-ID: 181242 [Multi-domain] Cd Length: 401 Bit Score: 270.50 E-value: 1.51e-86
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAIckARRGGFKDTL-PDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSV 128
Cdd:PRK08131 3 DAYIYDGLRSPF--GRHAGALASVrPDDLAATVIRRLLEKSGFPGDDIEDVILGCTNQAGEDSRNVARNALLLAGLPVTV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 129 PVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMST-------------------DHIPGGGFhgSNPRAQdfpk 189
Cdd:PRK08131 81 PGQTVNRLCASGLAAVIDAARAITCGEGDLYLAGGVESMSRapfvmgkaesafsrdakvfDTTIGARF--PNPKIV---- 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 190 ARDCLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdPETKAEKAIVVSVDDGVRPNS 269
Cdd:PRK08131 155 AQYGNDSMPETGDNVAAEFGISREDADRFAAQSQAKYQAAKEEGFFADEITPIEV----PQGRKLPPKLVAEDEHPRPSS 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 270 NMADLAKLKTVFkQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLA 349
Cdd:PRK08131 231 TVEALTKLKPLF-EGGVVTAGNASGINDGAAALLIGSRAAGEKYGLKPMARILSSAAAGVEPRIMGIGPVEAIKKALARA 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 350 GLNVSDIDLFEINEAFASQYVYSCKKLELDME--KVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCI 427
Cdd:PRK08131 310 GLTLDDMDIIEINEAFASQVLGCLKGLGVDFDdpRVNPNGGAIAVGHPLGASGARLALTAARELQRRGK--RYAVVSLCI 387
|
410
....*....|..
gi 30695564 428 GTGMGAAAVFER 439
Cdd:PRK08131 388 GVGQGLAMVIER 399
|
|
| PRK06504 |
PRK06504 |
acetyl-CoA C-acetyltransferase; |
53-439 |
3.23e-85 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180595 [Multi-domain] Cd Length: 390 Bit Score: 266.59 E-value: 3.23e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 53 IVAAYRTAicKARRGG-FKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDSVPVR 131
Cdd:PRK06504 6 IVAAARTA--GGRKGGrLAGWHPADLAAQVLDALVDRSGADPALIEDVIMGCVSQVGEQATNVARNAVLASKLPESVPGT 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESM--------STDHIPGGGFHGSNPRAQD-FPKARDCLLpMGitSE 202
Cdd:PRK06504 84 SIDRQCGSSQQALHFAAQAVMSGTMDIVIAAGVESMtrvpmgspSTLPAKNGLGHYKSPGMEErYPGIQFSQF-TG--AE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 203 NVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETKAEKaivvsVDDGVRPNSNMADLAKLKTVfK 282
Cdd:PRK06504 161 MMAKKYGLSKDQLDEFALQSHQRAIAATQAGKFKAEIVPLEITRADGSGEMHT-----VDEGIRFDATLEGIAGVKLI-A 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 283 QNGSTTAGNASQISDGAGAVLLMKrslamKKGLPILGV-----FRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDID 357
Cdd:PRK06504 235 EGGRLTAATASQICDGASGVMVVN-----ERGLKALGVkplarIHHMTVIGGDPVIMLEAPLPATERALKKAGMKIDDID 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 358 LFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVF 437
Cdd:PRK06504 310 LYEVNEAFASVPLAWLKATGADPERLNVNGGAIALGHPLGASGTKLMTTLVHALKQRGK--RYGLQTMCEGGGMANVTIV 387
|
..
gi 30695564 438 ER 439
Cdd:PRK06504 388 ER 389
|
|
| PRK08170 |
PRK08170 |
acetyl-CoA C-acetyltransferase; |
50-440 |
8.70e-85 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 181265 [Multi-domain] Cd Length: 426 Bit Score: 266.50 E-value: 8.70e-85
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTViAPGSQRAMECRVAAYFAGFPDSVP 129
Cdd:PRK08170 4 PVYIVDGARTPFLKAR-GGPGPFSASDLAVAAGRALLNRQPFAPDDLDEVILGCA-MPSPDEANIARVVALRLGCGEKVP 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 130 VRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIP-----------GGGFHGSNP--RAQDFPKARD---- 192
Cdd:PRK08170 82 AWTVQRNCASGMQALDSAAANIALGRADLVLAGGVEAMS--HAPllfsekmvrwlAGWYAAKSIgqKLAALGKLRPsyla 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 193 -------------CLLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKdEIIPvatkIVDPETKaekaiVV 259
Cdd:PRK08170 160 pvigllrgltdpvVGLNMGQTAEVLAHRFGITREQMDAYAARSHQRLAAAQAEGRLK-EVVP----LFDRDGK-----FY 229
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 260 SVDDGVRPNSNMADLAKLKTVF-KQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGP 338
Cdd:PRK08170 230 DHDDGVRPDSSMEKLAKLKPFFdRPYGRVTAGNSSQITDGACWLLLASEEAVKKYGLPPLGRIVDSQWAALDPSQMGLGP 309
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 339 AVAIPAATKLAGLNVSDIDLFEINEAFASQyVYSCKKL------------------ELDMEKVNVNGGAIAIGHPLGATG 400
Cdd:PRK08170 310 VHAATPLLQRHGLTLEDLDLWEINEAFAAQ-VLACLAAwadeeycreqlgldgalgELDRERLNVDGGAIALGHPVGASG 388
|
410 420 430 440
....*....|....*....|....*....|....*....|
gi 30695564 401 ARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFERG 440
Cdd:PRK08170 389 ARIVLHLLHALKRRGT--KRGIAAICIGGGQGGAMLLERV 426
|
|
| Thiolase_N |
pfam00108 |
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
51-308 |
3.97e-81 |
|
Thiolase, N-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 459676 [Multi-domain] Cd Length: 260 Bit Score: 251.45 E-value: 3.97e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 51 IVIVAAYRTAICKARrGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMEcRVAAYFAGFPDSVPV 130
Cdd:pfam00108 1 VVIVSAARTPFGSFG-GSLKDVSAVELGAEAIKAALERAGVDPEDVDEVIVGNVLQAGEGQNPA-RQAALKAGIPDSAPA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 131 RTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdHIPGGgfHGSNPRA---QDFPKARDCLLP----------- 196
Cdd:pfam00108 79 VTINKVCGSGLKAVYLAAQSIASGDADVVLAGGVESMS--HAPYA--LPTDARSglkHGDEKKHDLLIPdgltdafngyh 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 197 MGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETkaekaiVVSVDDGVRPNSNMADLAK 276
Cdd:pfam00108 155 MGLTAENVAKKYGISREEQDAFAVKSHQKAAAAPKAGKFKDEIVPVTVKGRKGKP------TVDKDEGIRPPTTAEPLAK 228
|
250 260 270
....*....|....*....|....*....|..
gi 30695564 277 LKTVFKQNGSTTAGNASQISDGAGAVLLMKRS 308
Cdd:pfam00108 229 LKPAFDKEGTVTAGNASPINDGAAAVLLMSES 260
|
|
| PRK06690 |
PRK06690 |
acetyl-CoA C-acyltransferase; |
52-438 |
7.15e-76 |
|
acetyl-CoA C-acyltransferase;
Pssm-ID: 180659 [Multi-domain] Cd Length: 361 Bit Score: 241.59 E-value: 7.15e-76
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 52 VIVAAYRTAICKaRRGGFKDTLPDDLLASVLKAVVERTsldPSEVGDIVVGTVIAPGSQRAmecRVAAYFAGFPDSVPVR 131
Cdd:PRK06690 4 VIVEAKRTPIGK-KNGMLKDYEVQQLAAPLLTFLSKGM---EREIDDVILGNVVGPGGNVA---RLSALEAGLGLHIPGV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDHIpgggfhgsNPRAQDFPKA---RDcllpMGITSENVAERF 208
Cdd:PRK06690 77 TIDRQCGAGLEAIRTACHFIQGGAGKCYIAGGVESTSTSPF--------QNRARFSPETigdPD----MGVAAEYVAERY 144
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 209 GVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIvdpetkaekaivvsvDDGVRPNSNMADL-AKLKTVFKQNGST 287
Cdd:PRK06690 145 NITREMQDEYACLSYKRTLQALEKGYIHEEILSFNGLL---------------DESIKKEMNYERIiKRTKPAFLHNGTV 209
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 288 TAGNASQISDGAGAVLLMKRSLAMKKGL-PILGVFRSfAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFA 366
Cdd:PRK06690 210 TAGNSCGVNDGACAVLVMEEGQARKLGYkPVLRFVRS-AVVGVDPNLPGTGPIFAVNKLLNEMNMKVEDIDYFEINEAFA 288
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 30695564 367 SQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRgkDCRFGVISMCIGTGMGAAAVFE 438
Cdd:PRK06690 289 SKVVACAKELQIPYEKLNVNGGAIALGHPYGASGAMLVTRLFYQAKRE--DMKYGIATLGIGGGIGLALLFE 358
|
|
| PRK06025 |
PRK06025 |
acetyl-CoA C-acetyltransferase; |
50-439 |
2.70e-69 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 235675 [Multi-domain] Cd Length: 417 Bit Score: 226.20 E-value: 2.70e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRT--AICKARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPDS 127
Cdd:PRK06025 3 EAYIIDAVRTprGIGKVGKGALAHLHPQHLAATVLKALAERNGLNTADVDDIIWSTSSQRGKQGGDLGRMAALDAGYDIK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 128 VPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMS--TDHIPGGGFHGSNPRAQDFPKAR-DCLLPM---GITS 201
Cdd:PRK06025 83 ASGVTLDRFCGGGITSVNLAAAQIMSGMEDLVIAGGTEMMSytAAMAAEDMAAGKPPLGMGSGNLRlRALHPQshqGVCG 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 202 ENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVatkivdpeTKAEKAIVVSVDDGVRPNSNMADLAKLKTVF 281
Cdd:PRK06025 163 DAIATMEGITREALDALGLESQRRAARAIKEGRFDKSLVPV--------YRDDGSVALDHEEFPRPQTTAEGLAALKPAF 234
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 282 K-------QNGSTT-------------------AGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMG 335
Cdd:PRK06025 235 TaiadyplDDKGTTyrglinqkypdleikhvhhAGNSSGVVDGAAALLLASKAYAEKHGLKPRARIVAMANMGDDPTLML 314
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 336 IGPavaIPAATKL---AGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMK 412
Cdd:PRK06025 315 NAP---VPAAKKVlakAGLTKDDIDLWEINEAFAVVAEKFIRDLDLDRDKVNVNGGAIALGHPIGATGSILIGTVLDELE 391
|
410 420
....*....|....*....|....*..
gi 30695564 413 RRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:PRK06025 392 RRGL--KRGLVTMCAAGGMAPAIIIER 416
|
|
| PRK06954 |
PRK06954 |
acetyl-CoA C-acetyltransferase; |
44-438 |
2.60e-65 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 180775 [Multi-domain] Cd Length: 397 Bit Score: 215.14 E-value: 2.60e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 44 MAAFGDDIVIVAAYRTAICkARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIaPGSQRAMECRVAAYFAG 123
Cdd:PRK06954 2 TAVDQDPIVIASAARTPMA-AFQGEFASLTAPQLGAAAIAAAVERAGLKPEQIDEVVMGCVL-PAGQGQAPARQAALGAG 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 124 FPDSVPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDH--IPG--GGFHGSNPRAQD------FPKARDC 193
Cdd:PRK06954 80 LPLSVGCTTVNKMCGSGMRAAMFAHDMLVAGSVDVIVAGGMESMTNAPylLPKarGGMRMGHGQVLDhmfldgLEDAYDK 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 194 LLPMGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATKIVDPETkaekaiVVSVDDGVRpNSNMAD 273
Cdd:PRK06954 160 GRLMGTFAEECAGEYGFTREAQDAFAIESLARAKRANEDGSFAWEIAPVTVAGKKGDT------VIDRDEQPF-KANPEK 232
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 274 LAKLKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNV 353
Cdd:PRK06954 233 IPTLKPAFSKTGTVTAANSSSISDGAAALVMMRASTAKRLGLAPLARVVGHSTFAQAPSKFTTAPVGAIRKLFEKNGWRA 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 354 SDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGA 433
Cdd:PRK06954 313 AEVDLFEINEAFAVVTMAAMKEHGLPHEKVNVNGGACALGHPIGASGARILVTLIGALRARGG--KRGVASLCIGGGEAT 390
|
....*
gi 30695564 434 AAVFE 438
Cdd:PRK06954 391 AMGIE 395
|
|
| PRK06366 |
PRK06366 |
acetyl-CoA C-acetyltransferase; |
50-438 |
1.06e-62 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 102340 [Multi-domain] Cd Length: 388 Bit Score: 208.33 E-value: 1.06e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 50 DIVIVAAYRTAICKARRGGFKDTLPDdLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRvAAYFAGFPDSVP 129
Cdd:PRK06366 3 DVYIVSAKRTAIGKFGRSFSKIKAPQ-LGGAAIKAVIDDAKLDPALVQEVIMGNVIQAGVGQNPAGQ-AAYHAGLPFGVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 130 VRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDH--IPGGGFHGSNPRAQDFPKARDCLLP----------- 196
Cdd:PRK06366 81 KYTVNVVCASGMLAVESAAREIMLGERDLVIAGGMENMSNAPflLPSDLRWGPKHLLHKNYKIDDAMLVdglidafyfeh 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 197 MGITSENVAERFGVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdpetkaekaivVSVDDGVRpNSNMADLAK 276
Cdd:PRK06366 161 MGVSAERTARKYGITREMADEYSVQSYERAIRATESGEFRNEIVPFND--------------LDRDEGIR-KTTMEDLAK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 277 LKTVFKQNGSTTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPavaIPAATKL---AGLNV 353
Cdd:PRK06366 226 LPPAFDKNGILTAGNSAQLSDGGSALVMASEKAINEYGLKPIARITGYESASLDPLDFVEAP---IPATRKLlekQNKSI 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 354 SDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRgkDCRFGVISMCIGTGMGA 433
Cdd:PRK06366 303 DYYDLVEHNEAFSIASIIVRDQLKIDNERFNVNGGAVAIGHPIGNSGSRIIVTLINALKTR--HMKTGLATLCHGGGGAH 380
|
....*
gi 30695564 434 AAVFE 438
Cdd:PRK06366 381 TLTLE 385
|
|
| Thiolase_C |
pfam02803 |
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl ... |
315-439 |
1.57e-60 |
|
Thiolase, C-terminal domain; Thiolase is reported to be structurally related to beta-ketoacyl synthase (pfam00109), and also chalcone synthase.
Pssm-ID: 397094 [Multi-domain] Cd Length: 123 Bit Score: 193.24 E-value: 1.57e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 315 LPILGVFRSFAVTGVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIAIGH 394
Cdd:pfam02803 1 LKPLARIRSYATAGVDPAIMGIGPAYAIPKALKKAGLTVNDIDLFEINEAFAAQALAVAKDLGIDPEKVNVNGGAIALGH 80
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 30695564 395 PLGATGARCVATLLHEMKRRGKdcRFGVISMCIGTGMGAAAVFER 439
Cdd:pfam02803 81 PLGASGARILVTLLHELKRRGG--KYGLASLCIGGGQGVAMIIER 123
|
|
| PRK09268 |
PRK09268 |
acetyl-CoA C-acetyltransferase; |
76-439 |
1.64e-53 |
|
acetyl-CoA C-acetyltransferase;
Pssm-ID: 236440 [Multi-domain] Cd Length: 427 Bit Score: 185.10 E-value: 1.64e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 76 DLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMeCRVAAYFAGFPDSVPVRTVNRQCSSGLQAVADVAASIRAGY 155
Cdd:PRK09268 33 DMLTAALDGLVDRFGLQGERLGEVVAGAVLKHSRDFNL-TRECVLGSALSPYTPAYDLQQACGTGLEAAILVANKIALGQ 111
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 156 YDIGIGAGVESMSTdhIPGGGFHGSNPRAQDFPKARDCL---------------------------LPMGITSENVAERF 208
Cdd:PRK09268 112 IDSGIAGGVDTTSD--APIAVNEGLRKILLELNRAKTTGdrlkalgklrpkhlapeiprngeprtgLSMGEHAAITAKEW 189
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 209 GVTREEQDMAAVESHKRAAAAIASGKLKDEIIPVATkivdpetkaekaivVSVDDGVRPNSNMADLAKLKTVF--KQNGS 286
Cdd:PRK09268 190 GISREAQDELAAASHQNLAAAYDRGFFDDLITPFLG--------------LTRDNNLRPDSSLEKLAKLKPVFgkGGRAT 255
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 287 TTAGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFA------VTGVEPSVMGigPAVAIPAATKLAGLNVSDIDLFE 360
Cdd:PRK09268 256 MTAGNSTPLTDGASVVLLASEEWAAEHGLPVLAYLVDAEtaavdfVHGKEGLLMA--PAYAVPRLLARNGLTLQDFDFYE 333
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 361 INEAFASQYVYSCKKLE-----------------LDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDcRfGVI 423
Cdd:PRK09268 334 IHEAFASQVLATLKAWEdeeycrerlgldaplgsIDRSKLNVNGSSLAAGHPFAATGGRIVATLAKLLAEKGSG-R-GLI 411
|
410
....*....|....*.
gi 30695564 424 SMCIGTGMGAAAVFER 439
Cdd:PRK09268 412 SICAAGGQGVTAILER 427
|
|
| nondecarbox_cond_enzymes |
cd00826 |
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic ... |
54-438 |
1.94e-52 |
|
nondecarboxylating condensing enzymes; In general, thiolases catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. There are 2 functional different classes: thiolase-I (3-ketoacyl-CoA thiolase) and thiolase-II (acetoacetyl-CoA thiolase). Thiolase-I can cleave longer fatty acid molecules and plays an important role in the beta-oxidative degradation of fatty acids. Thiolase-II has a high substrate specificity. Although it can cleave acetoacyl-CoA, its main function is the synthesis of acetoacyl-CoA from two molecules of acetyl-CoA, which gives it importance in several biosynthetic pathways.
Pssm-ID: 238422 [Multi-domain] Cd Length: 393 Bit Score: 181.15 E-value: 1.94e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 54 VAAYRTAICK--ARRGGFKDTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIaPGSQRAMECRVAAYFAGFPDSVPVR 131
Cdd:cd00826 1 AGAAMTAFGKfgGENGADANDLAHEAGAKAIAAALEPAGVAAGAVEEACLGQVL-GAGEGQNCAQQAAMHAGGLQEAPAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 132 TVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMSTDhipgggfhgsnprAQDFPKARDCllpmgitseNVAERFGVT 211
Cdd:cd00826 80 GMNNLCGSGLRALALAMQLIAGGDANCILAGGFEKMETS-------------AENNAKEKHI---------DVLINKYGM 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 212 REEQDMAAVESHKRAAAAIASGKLKDEIIPVATKivdpETKAEKAIVVSVDDGVRPNSNMADLAKLKTVFKQNGSTTAGN 291
Cdd:cd00826 138 RACPDAFALAGQAGAEAAEKDGRFKDEFAKFGVK----GRKGDIHSDADEYIQFGDEASLDEIAKLRPAFDKEDFLTAGN 213
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 292 ASQISDGAGAVLLMKRSLAMKKGLPI-------LGVFRSFAVTGVEPS----VMGIGPAVAIPAATKLAGLNVSDIDLFE 360
Cdd:cd00826 214 ACGLNDGAAAAILMSEAEAQKHGLQSkareiqaLEMITDMASTFEDKKvikmVGGDGPIEAARKALEKAGLGIGDLDLIE 293
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 361 INEAFASQYVYSCKKLELDMEK------------------VNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDC---R 419
Cdd:cd00826 294 AHDAFAANACATNEALGLCPEGqggalvdrgdntyggksiINPNGGAIAIGHPIGASGAAICAELCFELKGEAGKRqgaG 373
|
410
....*....|....*....
gi 30695564 420 FGVISMCIGTGMGAAAVFE 438
Cdd:cd00826 374 AGLALLCIGGGGGAAMCIE 392
|
|
| cond_enzymes |
cd00327 |
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) ... |
289-436 |
2.58e-18 |
|
Condensing enzymes; Family of enzymes that catalyze a (decarboxylating or non-decarboxylating) Claisen-like condensation reaction. Members are share strong structural similarity, and are involved in the synthesis and degradation of fatty acids, and the production of polyketides, a diverse group of natural products.
Pssm-ID: 238201 [Multi-domain] Cd Length: 254 Bit Score: 84.42 E-value: 2.58e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 289 AGNASQISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTGVEPS----VMGIGPAVAIPAATKLAGLNVSDIDLFEINEA 364
Cdd:cd00327 94 GSEEFVFGDGAAAAVVESEEHALRRGAHPQAEIVSTAATFDGASmvpaVSGEGLARAARKALEGAGLTPSDIDYVEAHGT 173
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 365 FASQYVYSCKKLELDMEKVN---VNGGAIAIGHPLGATGARCVATLLHEMKRRGKDC-----RFGVISMCIGTGMGAAAV 436
Cdd:cd00327 174 GTPIGDAVELALGLDPDGVRspaVSATLIMTGHPLGAAGLAILDELLLMLEHEFIPPtprepRTVLLLGFGLGGTNAAVV 253
|
|
| SCP-x_thiolase |
cd00829 |
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; ... |
71-437 |
2.88e-17 |
|
Thiolase domain associated with sterol carrier protein (SCP)-x isoform and related proteins; SCP-2 has multiple roles in intracellular lipid circulation and metabolism. The N-terminal presequence in the SCP-x isoform represents a peroxisomal 3-ketacyl-Coa thiolase specific for branched-chain acyl CoAs, which is proteolytically cleaved from the sterol carrier protein.
Pssm-ID: 238425 [Multi-domain] Cd Length: 375 Bit Score: 83.08 E-value: 2.88e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 71 DTLPDDLLASVLKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYFAGFPdsVPVRTVNRQCSSGLQAVADVAAS 150
Cdd:cd00829 13 DRSPLELAAEAARAALDDAGLEPADIDAVVVGNAAGGRFQSFPGALIAEYLGLLG--KPATRVEAAGASGSAAVRAAAAA 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 151 IRAGYYDIGIGAGVESMSTdhipGGGFHGSNPRAQDFPKARDcLLPMGITSENVA--------ERFGVTREEQDMAAVES 222
Cdd:cd00829 91 IASGLADVVLVVGAEKMSD----VPTGDEAGGRASDLEWEGP-EPPGGLTPPALYalaarrymHRYGTTREDLAKVAVKN 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 223 HKRAAA---AIasgkLKDEIIPV----ATKIVDPetkaekaivvsvddgvrpnsnmadlaklktvfkqngsTTAGNASQI 295
Cdd:cd00829 166 HRNAARnpyAQ----FRKPITVEdvlnSRMIADP-------------------------------------LRLLDCCPV 204
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 296 SDGAGAVLLMKRSLAMKKGLP---ILGV-FRSFAVTGVEPSVMGIGPAV--AIPAATKLAGLNVSDIDLFEINEAFASQ- 368
Cdd:cd00829 205 SDGAAAVVLASEERARELTDRpvwILGVgAASDTPSLSERDDFLSLDAArlAARRAYKMAGITPDDIDVAELYDCFTIAe 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 369 YVYS-----CKK-----------LELDME-KVNVNGGAIAIGHPLGATGARCVATLLHEMKRRG-----KDCRFGVISMc 426
Cdd:cd00829 285 LLALedlgfCEKgeggklvregdTAIGGDlPVNTSGGLLSKGHPLGATGLAQAVEAVRQLRGEAgarqvPGARVGLAHN- 363
|
410
....*....|.
gi 30695564 427 IGtGMGAAAVF 437
Cdd:cd00829 364 IG-GTGSAAVV 373
|
|
| PRK06289 |
PRK06289 |
acetyl-CoA acetyltransferase; Provisional |
76-402 |
6.43e-11 |
|
acetyl-CoA acetyltransferase; Provisional
Pssm-ID: 235771 [Multi-domain] Cd Length: 403 Bit Score: 63.94 E-value: 6.43e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 76 DLLASVLKAVVERTSLDPSEVGDIVVGTVIAP-----GSQRAMECRVAAYFAGFPDSvpvrtvnRQ---CSSGLQAVADV 147
Cdd:PRK06289 28 DLTREVVDGTLAAAGVDADDIEVVHVGNFFGElfagqGHLGAMPATVHPALWGVPAS-------RHeaaCASGSVATLAA 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 148 AASIRAGYYDIGIGAGVESMST-------DHIPGGGFHGSNPRAQDFPKARdcllPMGITSENVAERFGVTreeqdmaav 220
Cdd:PRK06289 101 MADLRAGRYDVALVVGVELMKTvpgdvaaEHLGAAAWTGHEGQDARFPWPS----MFARVADEYDRRYGLD--------- 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 221 ESHKRAAAAIASGKLKDEiiPVAT----KIVDPETKAEKAIVVSVDDGVRpnsnmadlaklktvfKQNgsttagnASQIS 296
Cdd:PRK06289 168 EEHLRAIAEINFANARRN--PNAQtrgwAFPDEATNDDDATNPVVEGRLR---------------RQD-------CSQVT 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 297 DGAGAVLLMK----RSLAMKKGLP-ILGVFRSFAVTGVEPSVMG------IGPAV--AIPAATKLAGLNVSDIDLFEINE 363
Cdd:PRK06289 224 DGGAGVVLASdaylRDYADARPIPrIKGWGHRTAPLGLEQKLDRsagdpyVLPHVrqAVLDAYRRAGVGLDDLDGFEVHD 303
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*..
gi 30695564 364 AF-ASQYVY-----------SCKKLE---LDME---KVNVNGGAIAIGHPLGATGAR 402
Cdd:PRK06289 304 CFtPSEYLAidhigltgpgeSWKAIEngeIAIGgrlPINPSGGLIGGGHPVGASGVR 360
|
|
| PRK06064 |
PRK06064 |
thiolase domain-containing protein; |
76-436 |
3.32e-10 |
|
thiolase domain-containing protein;
Pssm-ID: 235688 [Multi-domain] Cd Length: 389 Bit Score: 61.45 E-value: 3.32e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 76 DLLASVLKAVVERTSLDPSEVGDIVVGTVIAPG-SQRAMECRVAAYFAGFPdSVPVRTVNRQCSSGLQAVADVAASIRAG 154
Cdd:PRK06064 24 DLAVEAGLEALEDAGIDGKDIDAMYVGNMSAGLfVSQEHIAALIADYAGLA-PIPATRVEAACASGGAALRQAYLAVASG 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 155 YYDIGIGAGVESM-------STDHIPGGG------FHGSNPRAQDFPKARDCLlpmgitsenvaERFGVTREEQDMAAVE 221
Cdd:PRK06064 103 EADVVLAAGVEKMtdvptpdATEAIARAGdyeweeFFGATFPGLYALIARRYM-----------HKYGTTEEDLALVAVK 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 222 SHKRAAaaiasgklkdeiipvatkiVDPETKAEKAIvvSVDDGVrpNSNM-ADLAKLKtvfkqngsttagNASQISDGAG 300
Cdd:PRK06064 172 NHYNGS-------------------KNPYAQFQKEI--TVEQVL--NSPPvADPLKLL------------DCSPITDGAA 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 301 AVLLMK--------------RSLAMKKGLPILGVFRSFavTGVEPSVmgigpaVAIPAATKLAGLNVSDIDLFEINEAFA 366
Cdd:PRK06064 217 AVILASeekakeytdtpvwiKASGQASDTIALHDRKDF--TTLDAAV------VAAEKAYKMAGIEPKDIDVAEVHDCFT 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 367 SQYVYS------CKK---LELDMEK---------VNVNGGAIAIGHPLGATGARCVATLLHEMKRRGKDCRFGVISMCIG 428
Cdd:PRK06064 289 IAEILAyedlgfAKKgegGKLAREGqtyiggdipVNPSGGLKAKGHPVGATGVSQAVEIVWQLRGEAEKGRQQVIGAGYG 368
|
410
....*....|...
gi 30695564 429 T-----GMGAAAV 436
Cdd:PRK06064 369 LthnvgGTGHTAV 381
|
|
| PRK12578 |
PRK12578 |
thiolase domain-containing protein; |
82-400 |
9.81e-09 |
|
thiolase domain-containing protein;
Pssm-ID: 183606 [Multi-domain] Cd Length: 385 Bit Score: 57.16 E-value: 9.81e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 82 LKAVVERTSLDPSEVGDIVVGTVIAPGSQRAMECRVAAYfAGFPDSVPVRtVNRQCSSGLQAVADVAASIRAGYYDIGIG 161
Cdd:PRK12578 29 IKEALNDAGVSQTDIELVVVGSTAYRGIELYPAPIVAEY-SGLTGKVPLR-VEAMCATGLAASLTAYTAVASGLVDMAIA 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 162 AGVESM-----STDHIPGG---------GFHGSNpraqdFPKardcLLPMGITSEnvAERFGVTREEQDMAAVESHKRAA 227
Cdd:PRK12578 107 VGVDKMtevdtSTSLAIGGrggnyqweyHFYGTT-----FPT----YYALYATRH--MAVYGTTEEQMALVSVKAHKYGA 175
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 228 aaiasgklkdeiipvatkiVDPETKAEKAIVVsvdDGVRPNSNMADLAKLKtvfkqngsttagNASQISDGAGAVLLMK- 306
Cdd:PRK12578 176 -------------------MNPKAHFQKPVTV---EEVLKSRAISWPIKLL------------DSCPISDGSATAIFASe 221
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 307 ---RSLAMKKGLPILGVFRSFAVTGVEPSVMGIGPAVAIPA---ATKLAGLNVSDI------DLFEINEAFASQYVYSCK 374
Cdd:PRK12578 222 ekvKELKIDSPVWITGIGYANDYAYVARRGEWVGFKATQLAarqAYNMAKVTPNDIevatvhDAFTIAEIMGYEDLGFTE 301
|
330 340 350
....*....|....*....|....*....|....*...
gi 30695564 375 K-------LELDMEK-----VNVNGGAIAIGHPLGATG 400
Cdd:PRK12578 302 KgkggkfiEEGQSEKggkvgVNLFGGLKAKGHPLGATG 339
|
|
| PTZ00455 |
PTZ00455 |
3-ketoacyl-CoA thiolase; Provisional |
75-412 |
8.35e-07 |
|
3-ketoacyl-CoA thiolase; Provisional
Pssm-ID: 240424 [Multi-domain] Cd Length: 438 Bit Score: 51.05 E-value: 8.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 75 DDLLASVLKAVVERTSLDPSE--VGDIVVGTVIAP--------GSQRAMECRVAAYFAGFPDSVPVRtVNRQCSSGLQAV 144
Cdd:PTZ00455 49 EELLATAIQGTLENTGLDGKAalVDKVVVGNFLGElfssqghlGPAAVGSLGQSGASNALLYKPAMR-VEGACASGGLAV 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 145 ADVAASIRAGYYDIGIGAGVESMSTDHIPGGGFHGSnpRAQDFPKARD-------CLLpmgitsenvAERFGVTREEQDM 217
Cdd:PTZ00455 128 QSAWEALLAGTSDIALVVGVEVQTTVSARVGGDYLA--RAADYRRQRKlddftfpCLF---------AKRMKYIQEHGHF 196
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 218 AAVESHKRAAAAIASGKlKDEIIPVATKIVDPEtkaekaivvSVDDGVRPNSNMADLAKLKTVFKQNgsttagNASQISD 297
Cdd:PTZ00455 197 TMEDTARVAAKAYANGN-KNPLAHMHTRKLSLE---------FCTGASDKNPKFLGNETYKPFLRMT------DCSQVSD 260
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 298 GAGAVLLmkrslAMKKGLPILGVFRSFA-VTGVEPSVMGIG--------------PAVAIPAATKLAGLNVSDIDLFEIN 362
Cdd:PTZ00455 261 GGAGLVL-----ASEEGLQKMGLSPNDSrLVEIKSLACASGnlyedppdatrmftSRAAAQKALSMAGVKPSDLQVAEVH 335
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 30695564 363 EAF------------------ASQYVYSCKKLELDMEKVNVNGGAIAIGHPLGATGARCVATLLHEMK 412
Cdd:PTZ00455 336 DCFtiaellmyealgiaeyghAKDLIRNGATALEGRIPVNTGGGLLSFGHPVGATGVKQIMEVYRQMK 403
|
|
| PRK08256 |
PRK08256 |
lipid-transfer protein; Provisional |
128-403 |
1.45e-04 |
|
lipid-transfer protein; Provisional
Pssm-ID: 181327 [Multi-domain] Cd Length: 391 Bit Score: 43.73 E-value: 1.45e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 128 VPVRTVNRQCSSGLQAVADVAASIRAGYYDIGIGAGVESMStdhiPG---GGFHGSNPRAQDFPKARDCL-----LPM-- 197
Cdd:PRK08256 71 IPIVNVNNNCSTGSTALFLARQAVRSGAADCALALGFEQMQ----PGalgSVWDDRPSPLERFDKALAELqgfdpAPPal 146
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 198 ---GITSENVAERFGVTREEQDMAAVESHKRAAA---AIASGKLKDEIIPVATKIVDPETKAEkaivvsvddgvrpnsnm 271
Cdd:PRK08256 147 rmfGGAGREHMEKYGTTAETFAKIGVKARRHAANnpyAQFRDEYTLEDVLASPMIWGPLTRLQ----------------- 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 272 adlaklktvfkqngsttagnASQISDGAGAVLLMKRSLAMKKGLP----ILG--VFRSFAVTGVEPSVMG-IGPAVAIPA 344
Cdd:PRK08256 210 --------------------CCPPTCGAAAAIVCSEEFARKHGLDraveIVAqaMTTDTPSTFDGRSMIDlVGYDMTRAA 269
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 345 ATKL---AGLNVSDIDLFEINEAFASQYVYSCKKLEL----DMEK--------------VNVNGGAIAIGHPLGATG-AR 402
Cdd:PRK08256 270 AQQVyeqAGIGPEDIDVVELHDCFSANELLTYEALGLcpegEAEKfiddgdntyggrwvVNPSGGLLSKGHPLGATGlAQ 349
|
.
gi 30695564 403 C 403
Cdd:PRK08256 350 C 350
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
295-408 |
2.98e-04 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 42.91 E-value: 2.98e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 295 ISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVTG-----VEPSVMGIGPAVAIPAATKLAGLNVSDIDLfeIN------- 362
Cdd:cd00834 229 LGEGAGVLVLESLEHAKARGAKIYAEILGYGASSdayhiTAPDPDGEGAARAMRAALADAGLSPEDIDY--INahgtstp 306
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 30695564 363 -----EAFAsqyvysCKKLELD-MEKVNVNGGAIAIGHPLGATGA-RCVATLL 408
Cdd:cd00834 307 lndaaESKA------IKRVFGEhAKKVPVSSTKSMTGHLLGAAGAvEAIATLL 353
|
|
| PKS |
cd00833 |
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different ... |
295-360 |
4.07e-04 |
|
polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or more large multifunctional proteins and iterative type II PKSs, complexes of several monofunctional subunits.
Pssm-ID: 238429 [Multi-domain] Cd Length: 421 Bit Score: 42.55 E-value: 4.07e-04
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 30695564 295 ISDGAGAVLLMKRSLAMKKGLPILGVFRSFAVT-------GVEPSvmGIGPAVAIPAATKLAGLNVSDIDLFE 360
Cdd:cd00833 233 RGEGVGVVVLKRLSDALRDGDRIYAVIRGSAVNqdgrtkgITAPS--GEAQAALIRRAYARAGVDPSDIDYVE 303
|
|
| FabH |
COG0332 |
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl- ... |
320-438 |
2.46e-03 |
|
3-oxoacyl-[acyl-carrier-protein] synthase III [Lipid transport and metabolism]; 3-oxoacyl-[acyl-carrier-protein] synthase III is part of the Pathway/BioSystem: Fatty acid biosynthesis
Pssm-ID: 440101 [Multi-domain] Cd Length: 323 Bit Score: 39.71 E-value: 2.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 320 VFRsFAVTGVEPsvmgigpavAIPAATKLAGLNVSDIDLF-------EINEAFAsqyvyscKKLELDMEKVNVNggaiaI 392
Cdd:COG0332 218 VFK-FAVRNLPE---------VIREALEKAGLTLDDIDWFiphqanlRIIEAVA-------KRLGLPEEKVVVN-----I 275
|
90 100 110 120
....*....|....*....|....*....|....*....|....*....
gi 30695564 393 GHpLGATGARCVATLLHEMKRRGKDCRfGVISMCIGTGMG---AAAVFE 438
Cdd:COG0332 276 DR-YGNTSAASIPLALDEALREGRIKP-GDLVLLAGFGAGltwGAAVLR 322
|
|
| elong_cond_enzymes |
cd00828 |
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, ... |
252-414 |
3.09e-03 |
|
"elongating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type I and II and polyketide synthases.They are characterized by the utlization of acyl carrier protein (ACP) thioesters as primer substrates, as well as the nature of their active site residues.
Pssm-ID: 238424 [Multi-domain] Cd Length: 407 Bit Score: 39.73 E-value: 3.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 252 KAEKAIVVSVDD----GVRPNSNMADLAKLKTVFKQNGSTTAGNASQI--SDGAGAVLLMKRSLAMKKGLPILGVFRSFA 325
Cdd:cd00828 180 KADIVVVGGVEDpleeGLSGFANMGALSTAEEEPEEMSRPFDETRDGFveAEGAGVLVLERAELALARGAPIYGRVAGTA 259
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 326 VT--GVEPSVMGIGPAVAIPAATKLAGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNGGAIA-------IGHPL 396
Cdd:cd00828 260 STtdGAGRSVPAGGKGIARAIRTALAKAGLSLDDLDVISAHGTSTPANDVAESRAIAEVAGALGAPLPvtaqkalFGHSK 339
|
170
....*....|....*...
gi 30695564 397 GATGARCVATLLHEMKRR 414
Cdd:cd00828 340 GAAGALQLIGALQSLEHG 357
|
|
| PRK07314 |
PRK07314 |
beta-ketoacyl-ACP synthase II; |
297-401 |
3.61e-03 |
|
beta-ketoacyl-ACP synthase II;
Pssm-ID: 235987 [Multi-domain] Cd Length: 411 Bit Score: 39.39 E-value: 3.61e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 297 DGAGAVLLMKRSLAMKKGLPILGVFRSFAVTG-----VEPSVMGIGPAVAIPAATKLAGLNVSDIDLF-------EINEA 364
Cdd:PRK07314 232 EGAGILVLEELEHAKARGAKIYAEVVGYGMTGdayhmTAPAPDGEGAARAMKLALKDAGINPEDIDYInahgtstPAGDK 311
|
90 100 110
....*....|....*....|....*....|....*...
gi 30695564 365 FASQYVyscKKLELD-MEKVNVNGGAIAIGHPLGATGA 401
Cdd:PRK07314 312 AETQAI---KRVFGEhAYKVAVSSTKSMTGHLLGAAGA 346
|
|
| KAS_III |
cd00830 |
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty ... |
295-436 |
4.02e-03 |
|
Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP. KASIII initiates this process by specifically using acetyl-CoA over acyl-CoA.
Pssm-ID: 238426 [Multi-domain] Cd Length: 320 Bit Score: 39.06 E-value: 4.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 295 ISDGAGAVLLMKRSLAMKKGLPILG------------VFRsFAVTGVEPSVMgigpavaipAATKLAGLNVSDIDLF--- 359
Cdd:cd00830 180 GSDGSGADLLTIPAGGSRSPFEDAEggdpylvmdgreVFK-FAVRLMPESIE---------EALEKAGLTPDDIDWFvph 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 360 ----EINEAFAsqyvyscKKLELDMEKVNVNggaiaiGHPLGATGARCVATLLHEMKRRGKDCRFGVISMC-IGTGM--G 432
Cdd:cd00830 250 qanlRIIEAVA-------KRLGLPEEKVVVN------LDRYGNTSAASIPLALDEAIEEGKLKKGDLVLLLgFGAGLtwG 316
|
....
gi 30695564 433 AAAV 436
Cdd:cd00830 317 AALL 320
|
|
| PRK05952 |
PRK05952 |
beta-ketoacyl-ACP synthase; |
300-405 |
4.55e-03 |
|
beta-ketoacyl-ACP synthase;
Pssm-ID: 235653 [Multi-domain] Cd Length: 381 Bit Score: 39.26 E-value: 4.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 300 GAVLLMK-RSLAMKKGLPILGVFRSFAVT-----GVEPSVMGIGPAVAIPAATKLAGLNVSDIDLF-------EINEAFA 366
Cdd:PRK05952 212 GAILVLEsAELAQKRGAKIYGQILGFGLTcdayhMSAPEPDGKSAIAAIQQCLARSGLTPEDIDYIhahgtatRLNDQRE 291
|
90 100 110
....*....|....*....|....*....|....*....
gi 30695564 367 SQYVYSckkleLDMEKVNVNGGAIAIGHPLGATGARCVA 405
Cdd:PRK05952 292 ANLIQA-----LFPHRVAVSSTKGATGHTLGASGALGVA 325
|
|
| ACP_syn_III_C |
pfam08541 |
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on ... |
349-438 |
5.79e-03 |
|
3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal; This domain is found on 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III EC:2.3.1.41, the enzyme responsible for initiating the chain of reactions of the fatty acid synthase in plants and bacteria.
Pssm-ID: 430060 Cd Length: 90 Bit Score: 35.94 E-value: 5.79e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 349 AGLNVSDIDLFEINEAFASQYVYSCKKLELDMEKVNVNggaiaIGHpLGATGARCVATLLHEMKRRGKDCRFGVISMCiG 428
Cdd:pfam08541 4 AGLTPEDIDWFVPHQANLRIIDAVAKRLGLPPEKVVVN-----LDE-YGNTSAASIPLALDEAVEEGKLKPGDLVLLV-G 76
|
90
....*....|...
gi 30695564 429 TGMG---AAAVFE 438
Cdd:pfam08541 77 FGAGltwGAALLR 89
|
|
| KAS_I_II |
cd00834 |
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible ... |
84-169 |
1.00e-02 |
|
Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.
Pssm-ID: 238430 [Multi-domain] Cd Length: 406 Bit Score: 38.29 E-value: 1.00e-02
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 30695564 84 AVVERTSLDPSEVGdIVVGTVIapGSQRAMECRVAAYFAGFPDSVPVRTVNRQ-------------------------CS 138
Cdd:cd00834 86 AGLDPEELDPERIG-VVIGSGI--GGLATIEEAYRALLEKGPRRVSPFFVPMAlpnmaagqvairlglrgpnytvstaCA 162
|
90 100 110
....*....|....*....|....*....|.
gi 30695564 139 SGLQAVADVAASIRAGYYDIGIGAGVESMST 169
Cdd:cd00834 163 SGAHAIGDAARLIRLGRADVVIAGGAEALIT 193
|
|
| |
