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Conserved domains on  [gi|18423177|ref|NP_568738|]
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Transducin/WD40 repeat-like superfamily protein [Arabidopsis thaliana]

Protein Classification

WD40 repeat domain-containing protein( domain architecture ID 11455410)

WD40 repeat domain-containing protein similar to proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly

CATH:  2.130.10.10
PubMed:  10322433|8090199
SCOP:  4002744

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
147-344 5.92e-24

WD40 repeat [General function prediction only];


:

Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 102.30  E-value: 5.92e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGA-PLCRVWDVNASAAIASLSKEK 225
Cdd:COG2319 209 SVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSAdGTVRLWDLATGELLRTLTGHS 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 226 DEMFaSCRFSVDNSgsevlYVAAnTQRGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDst 305
Cdd:COG2319 289 GGVN-SVAFSPDGK-----LLAS-GSDDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWD-- 358

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 18423177 306 kMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 359 -LATGELLRtlTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
147-344 5.92e-24

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 102.30  E-value: 5.92e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGA-PLCRVWDVNASAAIASLSKEK 225
Cdd:COG2319 209 SVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSAdGTVRLWDLATGELLRTLTGHS 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 226 DEMFaSCRFSVDNSgsevlYVAAnTQRGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDst 305
Cdd:COG2319 289 GGVN-SVAFSPDGK-----LLAS-GSDDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWD-- 358

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 18423177 306 kMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 359 -LATGELLRtlTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 107-344 9.33e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 85.46  E-value: 9.33e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 107 LICALPNSCRLFDWENiieddnEEESEKVVKELKDVgqqLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHAS 186
Cdd:cd00200  67 ASGSSDKTIRLWDLET------GECVRTLTGHTSYV---SSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDW 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 187 VKSLTFSESGKFLVSLGAPLC-RVWDVNASAAIASLSKEKDEMFaSCRFSVDNSGsevLYVAANTqrgGSIITWDTtswr 265
Cdd:cd00200 138 VNSVAFSPDGTFVASSSQDGTiKLWDLRTGKCVATLTGHTGEVN-SVAFSPDGEK---LLSSSSD---GTIKLWDL---- 206

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 266 rRSSKLIKR----NNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTNQIVKkAHLGLVTALTFSPDSRCLVSVSFDSR 341
Cdd:cd00200 207 -STGKCLGTlrghENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLS-GHTNSVTSLAWSPDGKRLASGSADGT 284


                ...
gi 18423177 342 ARL 344
Cdd:cd00200 285 IRI 287
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 315-344 3.38e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 34.98  E-value: 3.38e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 18423177    315 KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:smart00320   9 KGHTGPVTSVAFSPDGKYLASGSDDGTIKL 38
 
Name Accession Description Interval E-value
WD40 COG2319
WD40 repeat [General function prediction only];
147-344 5.92e-24

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 102.30  E-value: 5.92e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGA-PLCRVWDVNASAAIASLSKEK 225
Cdd:COG2319 209 SVAFSPDGKLLASGSADGTVRLWDLATGKLLRTLTGHSGSVRSVAFSPDGRLLASGSAdGTVRLWDLATGELLRTLTGHS 288

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 226 DEMFaSCRFSVDNSgsevlYVAAnTQRGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDst 305
Cdd:COG2319 289 GGVN-SVAFSPDGK-----LLAS-GSDDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKTLASGSDDGTVRLWD-- 358

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 18423177 306 kMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 359 -LATGELLRtlTGHTGAVTSVAFSPDGRTLASGSADGTVRL 398
WD40 COG2319
WD40 repeat [General function prediction only];
147-344 1.91e-23

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 100.76  E-value: 1.91e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGA-PLCRVWDVNASAAIASLSKEK 225
Cdd:COG2319 167 SVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKLLASGSAdGTVRLWDLATGKLLRTLTGHS 246

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 226 DEMFaSCRFSVDNSgsevlYVAANTqRGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVLIIDst 305
Cdd:COG2319 247 GSVR-SVAFSPDGR-----LLASGS-ADGTVRLWDLATGELLRT-LTGHSGGVNSVAFSPDGKLLASGSDDGTVRLWD-- 316

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 18423177 306 kMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 317 -LATGKLLRtlTGHTGAVRSVAFSPDGKTLASGSDDGTVRL 356
WD40 COG2319
WD40 repeat [General function prediction only];
143-344 9.60e-23

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 98.83  E-value: 9.60e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 143 GQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGAP-LCRVWDVNASAAIASL 221
Cdd:COG2319  79 AAVLSVAFSPDGRLLASASADGTVRLWDLATGLLLRTLTGHTGAVRSVAFSPDGKTLASGSADgTVRLWDLATGKLLRTL 158

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 222 SKEKDEMFaSCRFSVDnsgSEVLYVAAntqRGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVLI 301
Cdd:COG2319 159 TGHSGAVT-SVAFSPD---GKLLASGS---DDGTVRLWDLATGKLLRT-LTGHTGAVRSVAFSPDGKLLASGSADGTVRL 230

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*
gi 18423177 302 IDstkMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 231 WD---LATGKLLRtlTGHSGSVRSVAFSPDGRLLASGSADGTVRL 272
WD40 COG2319
WD40 repeat [General function prediction only];
147-344 1.78e-22

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 98.06  E-value: 1.78e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSmKTLLNESKTHA-SVKSLTFSESGKFLVSLGA-PLCRVWDVNASAAIASLSKE 224
Cdd:COG2319 125 SVAFSPDGKTLASGSADGTVRLWDLAT-GKLLRTLTGHSgAVTSVAFSPDGKLLASGSDdGTVRLWDLATGKLLRTLTGH 203

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 225 KDEmFASCRFSVDN----SGSEvlyvaantqrGGSIITWDTTSWRRRSSkLIKRNNSISAFNVSADGKLLAVGTLEGDVL 300
Cdd:COG2319 204 TGA-VRSVAFSPDGkllaSGSA----------DGTVRLWDLATGKLLRT-LTGHSGSVRSVAFSPDGRLLASGSADGTVR 271

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 18423177 301 IIDstkMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:COG2319 272 LWD---LATGELLRtlTGHSGGVNSVAFSPDGKLLASGSDDGTVRL 314
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 107-344 9.33e-19

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 85.46  E-value: 9.33e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 107 LICALPNSCRLFDWENiieddnEEESEKVVKELKDVgqqLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHAS 186
Cdd:cd00200  67 ASGSSDKTIRLWDLET------GECVRTLTGHTSYV---SSVAFSPDGRILSSSSRDKTIKVWDVETGKCLTTLRGHTDW 137

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 187 VKSLTFSESGKFLVSLGAPLC-RVWDVNASAAIASLSKEKDEMFaSCRFSVDNSGsevLYVAANTqrgGSIITWDTtswr 265
Cdd:cd00200 138 VNSVAFSPDGTFVASSSQDGTiKLWDLRTGKCVATLTGHTGEVN-SVAFSPDGEK---LLSSSSD---GTIKLWDL---- 206

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 266 rRSSKLIKR----NNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTNQIVKkAHLGLVTALTFSPDSRCLVSVSFDSR 341
Cdd:cd00200 207 -STGKCLGTlrghENGVNSVAFSPDGYLLASGSEDGTIRVWDLRTGECVQTLS-GHTNSVTSLAWSPDGKRLASGSADGT 284


                ...
gi 18423177 342 ARL 344
Cdd:cd00200 285 IRI 287
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 147-344 1.63e-15

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 76.22  E-value: 1.63e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 147 SLSFNQDGTVLATGAEDGTLRVFEWPSMkTLLNESKTHA-SVKSLTFSESGKFLVSLGAP-LCRVWDVNASAAIASLSKE 224
Cdd:cd00200  14 CVAFSPDGKLLATGSGDGTIKVWDLETG-ELLRTLKGHTgPVRDVAASADGTYLASGSSDkTIRLWDLETGECVRTLTGH 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 225 KDEMFaSCRFSVDNSgsevlYVAAnTQRGGSIITWDTtswrrRSSKLIKR----NNSISAFNVSADGKLLAVGTLEGDVL 300
Cdd:cd00200  93 TSYVS-SVAFSPDGR-----ILSS-SSRDKTIKVWDV-----ETGKCLTTlrghTDWVNSVAFSPDGTFVASSSQDGTIK 160

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*.
gi 18423177 301 IIDstkMQTNQIVK--KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:cd00200 161 LWD---LRTGKCVAtlTGHTGEVNSVAFSPDGEKLLSSSSDGTIKL 203
WD40 COG2319
WD40 repeat [General function prediction only];
146-263 4.97e-08

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 54.53  E-value: 4.97e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 146 LSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGAP-LCRVWDVNASAAIASLSKE 224
Cdd:COG2319 292 NSVAFSPDGKLLASGSDDGTVRLWDLATGKLLRTLTGHTGAVRSVAFSPDGKTLASGSDDgTVRLWDLATGELLRTLTGH 371

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 18423177 225 KDEmFASCRFSVDN----SGSEvlyvaantqrGGSIITWDTTS 263
Cdd:COG2319 372 TGA-VTSVAFSPDGrtlaSGSA----------DGTVRLWDLAT 403
WD40 COG2319
WD40 repeat [General function prediction only];
142-213 1.12e-06

WD40 repeat [General function prediction only];


Pssm-ID: 441893 [Multi-domain]  Cd Length: 403  Bit Score: 50.29  E-value: 1.12e-06
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 18423177 142 VGQQLSLSFNQDGTVLATGAEDGTLRVFEWPSMKTLLNESKTHASVKSLTFSESGKFLVSLGAPLC-RVWDVN 213
Cdd:COG2319 330 TGAVRSVAFSPDGKTLASGSDDGTVRLWDLATGELLRTLTGHTGAVTSVAFSPDGRTLASGSADGTvRLWDLA 402
WD40 cd00200
WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions ...
 275-357 1.50e-04

WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.


Pssm-ID: 238121 [Multi-domain]  Cd Length: 289  Bit Score: 43.09  E-value: 1.50e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18423177 275 NNSISAFNVSADGKLLAVGTLEGDVLIIDSTKMQTnQIVKKAHLGLVTALTFSPDSRCLVSVSFDSRARLtVIKQKGEKR 354
Cdd:cd00200   9 TGGVTCVAFSPDGKLLATGSGDGTIKVWDLETGEL-LRTLKGHTGPVRDVAASADGTYLASGSSDKTIRL-WDLETGECV 86


                ...
gi 18423177 355 RVY 357
Cdd:cd00200  87 RTL 89
WD40 smart00320
WD40 repeats; Note that these repeats are permuted with respect to the structural repeats ...
 315-344 3.38e-03

WD40 repeats; Note that these repeats are permuted with respect to the structural repeats (blades) of the beta propeller domain.


Pssm-ID: 197651 [Multi-domain]  Cd Length: 40  Bit Score: 34.98  E-value: 3.38e-03
                           10        20        30
                   ....*....|....*....|....*....|
gi 18423177    315 KAHLGLVTALTFSPDSRCLVSVSFDSRARL 344
Cdd:smart00320   9 KGHTGPVTSVAFSPDGKYLASGSDDGTIKL 38
COG4946 COG4946
Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown] ...
 283-356 5.59e-03

Uncharacterized N-terminal domain of tricorn protease, contains WD40 repeats [Function unknown];


Pssm-ID: 443973 [Multi-domain]  Cd Length: 1072  Bit Score: 38.87  E-value: 5.59e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18423177  283 VSADGKLLAVGTLEGDVLIID-STKmQTNQIVKKAHLGLVTALTFSPDSRCLVsVSFDSRARLTVIK----QKGEKRRV 356
Cdd:COG4946  396 WSPDGKKIAFTDNRGRLWVVDlASG-KVRKVDTDGYGDGISDLAWSPDSKWLA-YSKPGPNQLSQIFlydvETGKTVQL 472
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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