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Conserved domains on  [gi|24639042|ref|NP_569899|]
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uncharacterized protein Dmel_CG32812, isoform A [Drosophila melanogaster]

Protein Classification

EF-hand domain-containing protein( domain architecture ID 1000101)

EF-hand (EFh) domain-containing protein may be involved in binding intracellular calcium and in calcium signal transduction

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
FRQ1 super family cl34916
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];
25-139 3.12e-03

Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];


The actual alignment was detected with superfamily member COG5126:

Pssm-ID: 444056 [Multi-domain]  Cd Length: 137  Bit Score: 36.69  E-value: 3.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639042  25 AEQLEQLHTRFRSLDRHQRGYLTPTDLLRIPQLSLNPLHRQIIDgffpsrDPSARIGFKQFVdtcsTILVPQFGRgsvrr 104
Cdd:COG5126   1 DLQRRKLDRRFDLLDADGDGVLERDDFEALFRRLWATLFSEADT------DGDGRISREEFV----AGMESLFEA----- 65

                        90       100       110
                ....*....|....*....|....*....|....*
gi 24639042 105 rdGRVQKLQLLSKMFDTRRSGCITRSDFRQIMRSI 139
Cdd:COG5126  66 --TVEPFARAAFDLLDTDGDGKISADEFRRLLTAL 98
 
Name Accession Description Interval E-value
FRQ1 COG5126
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];
25-139 3.12e-03

Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];


Pssm-ID: 444056 [Multi-domain]  Cd Length: 137  Bit Score: 36.69  E-value: 3.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639042  25 AEQLEQLHTRFRSLDRHQRGYLTPTDLLRIPQLSLNPLHRQIIDgffpsrDPSARIGFKQFVdtcsTILVPQFGRgsvrr 104
Cdd:COG5126   1 DLQRRKLDRRFDLLDADGDGVLERDDFEALFRRLWATLFSEADT------DGDGRISREEFV----AGMESLFEA----- 65

                        90       100       110
                ....*....|....*....|....*....|....*
gi 24639042 105 rdGRVQKLQLLSKMFDTRRSGCITRSDFRQIMRSI 139
Cdd:COG5126  66 --TVEPFARAAFDLLDTDGDGKISADEFRRLLTAL 98
 
Name Accession Description Interval E-value
FRQ1 COG5126
Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];
25-139 3.12e-03

Ca2+-binding protein, EF-hand superfamily [Signal transduction mechanisms];


Pssm-ID: 444056 [Multi-domain]  Cd Length: 137  Bit Score: 36.69  E-value: 3.12e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 24639042  25 AEQLEQLHTRFRSLDRHQRGYLTPTDLLRIPQLSLNPLHRQIIDgffpsrDPSARIGFKQFVdtcsTILVPQFGRgsvrr 104
Cdd:COG5126   1 DLQRRKLDRRFDLLDADGDGVLERDDFEALFRRLWATLFSEADT------DGDGRISREEFV----AGMESLFEA----- 65

                        90       100       110
                ....*....|....*....|....*....|....*
gi 24639042 105 rdGRVQKLQLLSKMFDTRRSGCITRSDFRQIMRSI 139
Cdd:COG5126  66 --TVEPFARAAFDLLDTDGDGKISADEFRRLLTAL 98
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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