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Conserved domains on  [gi|18858011|ref|NP_572312|]
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uncharacterized protein Dmel_CG12219 [Drosophila melanogaster]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-91 9.99e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


:

Pssm-ID: 214871  Cd Length: 73  Bit Score: 49.44  E-value: 9.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18858011      2 ICRLCLNalDEQSAVLLFDGAGGASapapddeddgkampesyLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNFW 81
Cdd:smart00868   1 VCRLCLS--ESENLVSIFDESSEAS-----------------LAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFR 61

                           90
                   ....*....|
gi 18858011     82 KLVELKQTTL 91
Cdd:smart00868  62 ERCRESDELL 71
zf-H2C2_2 pfam13465
Zinc-finger double domain;
152-177 1.01e-03

Zinc-finger double domain;


:

Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.01e-03
                          10        20
                  ....*....|....*....|....*.
gi 18858011   152 YLEEHIATHTGDRPIACPYCEMAFRC 177
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 super family cl26169
hypothetical protein
 117-189 1.14e-03

hypothetical protein


The actual alignment was detected with superfamily member PHA00733:

Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 1.14e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18858011  117 PQLLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHI--ATHTgdrpIACPYCEMAFRCRSNMYTHVKSKH 189
Cdd:PHA00733  53 PQLLDESSYLYKLLTSKAVSPYVCPLCLMPFSSSVSLKQHIryTEHS----KVCPVCGKEFRNTDSTLDHVCKKH 123
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-91 9.99e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 49.44  E-value: 9.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18858011      2 ICRLCLNalDEQSAVLLFDGAGGASapapddeddgkampesyLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNFW 81
Cdd:smart00868   1 VCRLCLS--ESENLVSIFDESSEAS-----------------LAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFR 61

                           90
                   ....*....|
gi 18858011     82 KLVELKQTTL 91
Cdd:smart00868  62 ERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-80 1.53e-07

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 48.99  E-value: 1.53e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18858011     2 ICRLCLNALDEQSAVLlfdgaggasapapddEDDGKAMPesyLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNF 80
Cdd:pfam07776   1 VCRLCLDESDELIPIF---------------DPSDSEKT---LAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSF 61
zf-H2C2_2 pfam13465
Zinc-finger double domain;
152-177 1.01e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.01e-03
                          10        20
                  ....*....|....*....|....*.
gi 18858011   152 YLEEHIATHTGDRPIACPYCEMAFRC 177
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 117-189 1.14e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 1.14e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18858011  117 PQLLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHI--ATHTgdrpIACPYCEMAFRCRSNMYTHVKSKH 189
Cdd:PHA00733  53 PQLLDESSYLYKLLTSKAVSPYVCPLCLMPFSSSVSLKQHIryTEHS----KVCPVCGKEFRNTDSTLDHVCKKH 123
 
Name Accession Description Interval E-value
zf-AD smart00868
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-91 9.99e-08

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 214871  Cd Length: 73  Bit Score: 49.44  E-value: 9.99e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 18858011      2 ICRLCLNalDEQSAVLLFDGAGGASapapddeddgkampesyLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNFW 81
Cdd:smart00868   1 VCRLCLS--ESENLVSIFDESSEAS-----------------LAEKIEECTGIEIEPDDGLPKVICGDCLEKLESFHKFR 61

                           90
                   ....*....|
gi 18858011     82 KLVELKQTTL 91
Cdd:smart00868  62 ERCRESDELL 71
zf-AD pfam07776
Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical ...
 2-80 1.53e-07

Zinc-finger associated domain (zf-AD); The zf-AD domain, also known as ZAD, forms an atypical treble-cleft-like zinc co-ordinating fold. The zf-AD domain is thought to be involved in mediating dimer formation, but does not bind to DNA.


Pssm-ID: 462262  Cd Length: 75  Bit Score: 48.99  E-value: 1.53e-07
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 18858011     2 ICRLCLNALDEQSAVLlfdgaggasapapddEDDGKAMPesyLVQLISIHLYLCLSRDDAISTCICTECCSQLESFHNF 80
Cdd:pfam07776   1 VCRLCLDESDELIPIF---------------DPSDSEKT---LAEILEDCTGIELDPNDLLPKQICERCLSKLQEFYSF 61
zf-H2C2_2 pfam13465
Zinc-finger double domain;
152-177 1.01e-03

Zinc-finger double domain;


Pssm-ID: 463886 [Multi-domain]  Cd Length: 26  Bit Score: 36.58  E-value: 1.01e-03
                          10        20
                  ....*....|....*....|....*.
gi 18858011   152 YLEEHIATHTGDRPIACPYCEMAFRC 177
Cdd:pfam13465   1 NLKRHMRTHTGEKPYKCPECGKSFKS 26
PHA00733 PHA00733
hypothetical protein
 117-189 1.14e-03

hypothetical protein


Pssm-ID: 177301  Cd Length: 128  Bit Score: 39.09  E-value: 1.14e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 18858011  117 PQLLLEPAEEPKVVTPTTANKFPCMFCEKSFKMRRYLEEHI--ATHTgdrpIACPYCEMAFRCRSNMYTHVKSKH 189
Cdd:PHA00733  53 PQLLDESSYLYKLLTSKAVSPYVCPLCLMPFSSSVSLKQHIryTEHS----KVCPVCGKEFRNTDSTLDHVCKKH 123
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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