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Conserved domains on  [gi|19075204|ref|NP_587704|]
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protein mug135 [Schizosaccharomyces pombe]

Protein Classification

DUF1773 domain-containing protein( domain architecture ID 10554277)

DUF1773 domain-containing protein similar to Schizosaccharomyces pombe meiotically up-regulated gene 2 protein, meiotic expression up-regulated protein 23 and UPF0612 protein new22

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 261-317 5.47e-20

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


:

Pssm-ID: 400766  Cd Length: 58  Bit Score: 82.39  E-value: 5.47e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19075204   261 DMRLSRNNNMIMRSFAQPITEVPFFNGDIP-DPNLPRITRIEDIDSLSEENCTRYLKG 317
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPeDYELPPIGSIEDIDNLSKEQCSFYLPG 58
PTZ00121 super family cl31754
MAEBL; Provisional
 115-228 1.59e-06

MAEBL; Provisional


The actual alignment was detected with superfamily member PTZ00121:

Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDKAEW----KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEWKKAREEDK 184
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKAdelkKAAAAKKKADEakKKAEEKKKADEakKKAEEAKKADEakKKAEEAKKAEEAKKKAEEA 1469

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 19075204   185 EwrnSMDEWRKSMDEWRKSmDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1470 K---KADEAKKKAEEAKKA-DEAKKKAEEAKKKADEAKKAAEAK 1509
 
Name Accession Description Interval E-value
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 261-317 5.47e-20

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


Pssm-ID: 400766  Cd Length: 58  Bit Score: 82.39  E-value: 5.47e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19075204   261 DMRLSRNNNMIMRSFAQPITEVPFFNGDIP-DPNLPRITRIEDIDSLSEENCTRYLKG 317
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPeDYELPPIGSIEDIDNLSKEQCSFYLPG 58
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 1.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDKAEW----KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEWKKAREEDK 184
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKAdelkKAAAAKKKADEakKKAEEKKKADEakKKAEEAKKADEakKKAEEAKKAEEAKKKAEEA 1469

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 19075204   185 EwrnSMDEWRKSMDEWRKSmDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1470 K---KADEAKKKAEEAKKA-DEAKKKAEEAKKKADEAKKAAEAK 1509
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 37-273 1.36e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204     37 EIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDN-DECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFR 115
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAlRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    116 REMGEWKKAREEDKAEWKKAREE---DKAEWKKAREE----------------DKAEWKKAREEDKAEWKKAREEDKAEW 176
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQieqLKEELKALREAldelraeltllneeaaNLRERLESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    177 KKAREEDKEWRNSMDEWRKSMDEWRKSMDEWRKSmdewRKSTDEWRKSTDERLENLLNIVREILDVQRDMRNDLSNLTRK 256
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNE----RASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          250
                   ....*....|....*..
gi 19075204    257 VDRMDMRLSRNNNMIMR 273
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDN 940
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 122-195 1.22e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.21  E-value: 1.22e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19075204   122 KKAREEDKAEWKKAREEDKAEWKKAREedkAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRK 195
Cdd:TIGR02794 158 AKAAAEAKKKAEEAKKKAEAEAKAKAE---AEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAAAAEAERK 228
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
123-269 4.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.98  E-value: 4.31e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204 123 KAREEDKAEWKKAREEdKAEWKKAREEDKAEWKKAREE-DKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRKSMDEWR 201
Cdd:COG4717  81 KEAEEKEEEYAELQEE-LEELEEELEELEAELEELREElEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR 159

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075204 202 ksmdEWRKSMDEWRKSTDEWRKSTDERLENLLNIVREILdvqRDMRNDLSNLTRKVDRMDMRLSRNNN 269
Cdd:COG4717 160 ----ELEEELEELEAELAELQEELEELLEQLSLATEEEL---QDLAEELEELQQRLAELEEELEEAQE 220
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 114-238 4.58e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 38.83  E-value: 4.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   114 FRREMGEWKKAREEDKAewKKAREEDKAEWKKAREEDKAEWKKAREEDKAEwkKAREEDKAEWKKAREEDKEWRNSMDEW 193
Cdd:pfam05262 196 FRRDMTDLKERESQEDA--KRAQQLKEELDKKQIDADKAQQKADFAQDNAD--KQRDEVRQKQQEAKNLPKPADTSSPKE 271

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 19075204   194 RKSMDEWRKSMDEwrKSMDEWRKSTDEWRKSTDERLENLLNIVRE 238
Cdd:pfam05262 272 DKQVAENQKREIE--KAQIEIKKNDEEALKAKDHKAFDLKQESKA 314
 
Name Accession Description Interval E-value
DUF1773 pfam08593
Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene ...
 261-317 5.47e-20

Domain of unknown function; This is the C-terminal part of some meiotically up-regulated gene products from fission yeast. The actual function is not yet known but the proteins are likely to be cell-surface glycoproteins.


Pssm-ID: 400766  Cd Length: 58  Bit Score: 82.39  E-value: 5.47e-20
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 19075204   261 DMRLSRNNNMIMRSFAQPITEVPFFNGDIP-DPNLPRITRIEDIDSLSEENCTRYLKG 317
Cdd:pfam08593   1 HFLFSKNENFSKRKNGYPASPVPFLNGEEPeDYELPPIGSIEDIDNLSKEQCSFYLPG 58
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 1.59e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 50.14  E-value: 1.59e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDKAEW----KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEW--KKAREEDKAEWKKAREEDK 184
Cdd:PTZ00121 1390 KKKADEAKKKAEEDKKKAdelkKAAAAKKKADEakKKAEEKKKADEakKKAEEAKKADEakKKAEEAKKAEEAKKKAEEA 1469

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....
gi 19075204   185 EwrnSMDEWRKSMDEWRKSmDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1470 K---KADEAKKKAEEAKKA-DEAKKKAEEAKKKADEAKKAAEAK 1509
PTZ00121 PTZ00121
MAEBL; Provisional
 40-228 2.27e-06

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 49.75  E-value: 2.27e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    40 AKKKLLELERKALEDKEKNLNFVVESERT---LFNSKKRAfDNDECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFRR 116
Cdd:PTZ00121 1327 AKKKADAAKKKAEEAKKAAEAAKAEAEAAadeAEAAEEKA-EAAEKKKEEAKKKADAAKKKAEEKKKADEAKKKAEEDKK 1405

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   117 EMGEWKKAREEDKAE---WKKAREEDKAEW--KKAREEDKAEW--KKAREEDKAE--WKKAREEDKAEWKKAREEDK--- 184
Cdd:PTZ00121 1406 KADELKKAAAAKKKAdeaKKKAEEKKKADEakKKAEEAKKADEakKKAEEAKKAEeaKKKAEEAKKADEAKKKAEEAkka 1485

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|
gi 19075204   185 -EWRNSMDEWRKSMDEWRKSMDEwRKSMDEWRKS-----TDEWRKSTDER 228
Cdd:PTZ00121 1486 dEAKKKAEEAKKKADEAKKAAEA-KKKADEAKKAeeakkADEAKKAEEAK 1534
SMC_prok_B TIGR02168
chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of ...
 37-273 1.36e-05

chromosome segregation protein SMC, common bacterial type; SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins]


Pssm-ID: 274008 [Multi-domain]  Cd Length: 1179  Bit Score: 46.97  E-value: 1.36e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204     37 EIAAKKKLLELERKALEDKEKNLNFVVESERTLFNSKKRAFDN-DECYNDRCKLFRGIVNEWGRSERTLDSLDEPPAWFR 115
Cdd:TIGR02168  688 ELEEKIAELEKALAELRKELEELEEELEQLRKELEELSRQISAlRKDLARLEAEVEQLEERIAQLSKELTELEAEIEELE 767

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    116 REMGEWKKAREEDKAEWKKAREE---DKAEWKKAREE----------------DKAEWKKAREEDKAEWKKAREEDKAEW 176
Cdd:TIGR02168  768 ERLEEAEEELAEAEAEIEELEAQieqLKEELKALREAldelraeltllneeaaNLRERLESLERRIAATERRLEDLEEQI 847

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    177 KKAREEDKEWRNSMDEWRKSMDEWRKSMDEWRKSmdewRKSTDEWRKSTDERLENLLNIVREILDVQRDMRNDLSNLTRK 256
Cdd:TIGR02168  848 EELSEDIESLAAEIEELEELIEELESELEALLNE----RASLEEALALLRSELEELSEELRELESKRSELRRELEELREK 923

                          250
                   ....*....|....*..
gi 19075204    257 VDRMDMRLSRNNNMIMR 273
Cdd:TIGR02168  924 LAQLELRLEGLEVRIDN 940
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 3.02e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 46.29  E-value: 3.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDK----AEWKKAREEDKA-EWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNS 189
Cdd:PTZ00121 1314 AKKADEAKKKAEEAKkkadAAKKKAEEAKKAaEAAKAEAEAAADEAEAAEEKAEAAEKKKEEAKKKADAAKKKAEEKKKA 1393

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 19075204   190 mDEWRKSMDEWRKSMDEWRKSMDEwRKSTDEWRKSTDER 228
Cdd:PTZ00121 1394 -DEAKKKAEEDKKKADELKKAAAA-KKKADEAKKKAEEK 1430
PTZ00121 PTZ00121
MAEBL; Provisional
 41-237 9.61e-05

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 44.36  E-value: 9.61e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    41 KKKLLELERKALEDKEKNlnfvvESERTLFNSKKRAFDNDECYNDRCKlfrgiVNEWGRSERTLDSLDEPPAWFRREMGE 120
Cdd:PTZ00121 1469 AKKADEAKKKAEEAKKAD-----EAKKKAEEAKKKADEAKKAAEAKKK-----ADEAKKAEEAKKADEAKKAEEAKKADE 1538

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   121 WKKAREEDKA-------EWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNSMDEW 193
Cdd:PTZ00121 1539 AKKAEEKKKAdelkkaeELKKAEEKKKAEEAKKAEEDKNMALRKAEEAKKAEEARIEEVMKLYEEEKKMKAEEAKKAEEA 1618

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....
gi 19075204   194 RKSMDEWRKSMDEWRKSMDEWRKSTDEWRKSTDERLENLLNIVR 237
Cdd:PTZ00121 1619 KIKAEELKKAEEEKKKVEQLKKKEAEEKKKAEELKKAEEENKIK 1662
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 2.06e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.59  E-value: 2.06e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDKAEWKKAREED----KAEWKKAREEDK---AEWKKAREEDK--AEWKKAREEDKAEWKKAREEDKE 185
Cdd:PTZ00121 1634 KVEQLKKKEAEEKKKAEELKKAEEEnkikAAEEAKKAEEDKkkaEEAKKAEEDEKkaAEALKKEAEEAKKAEELKKKEAE 1713

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 19075204   186 WRNSMDEWRKSMDEWRKSMDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1714 EKKKAEELKKAEEENKIKAEEAKKEAEEDKKKAEEAKKDEEEK 1756
PTZ00121 PTZ00121
MAEBL; Provisional
 122-228 2.31e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 43.21  E-value: 2.31e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   122 KKAREEDKAE--WKKAREEDKAEW--KKAREEDKA-EWKKAREEDKA---EWKKAREEDKA--EWKKAREEDKEWRNSMD 191
Cdd:PTZ00121 1451 KKAEEAKKAEeaKKKAEEAKKADEakKKAEEAKKAdEAKKKAEEAKKkadEAKKAAEAKKKadEAKKAEEAKKADEAKKA 1530

                          90       100       110
                  ....*....|....*....|....*....|....*..
gi 19075204   192 EWRKSMDEWRKSmdEWRKSMDEWRKStDEWRKSTDER 228
Cdd:PTZ00121 1531 EEAKKADEAKKA--EEKKKADELKKA-EELKKAEEKK 1564
PRK00106 PRK00106
ribonuclease Y;
134-232 2.91e-04

ribonuclease Y;


Pssm-ID: 178867 [Multi-domain]  Cd Length: 535  Bit Score: 42.55  E-value: 2.91e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204  134 KAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRKSMDEWRKSMDEWRKSMDE 213
Cdd:PRK00106  50 KAERDAEHIKKTAKRESKALKKELLLEAKEEARKYREEIEQEFKSERQELKQIESRLTERATSLDRKDENLSSKEKTLES 129

                         90
                 ....*....|....*....
gi 19075204  214 WRKSTDEWRKSTDERLENL 232
Cdd:PRK00106 130 KEQSLTDKSKHIDEREEQV 148
PRK12704 PRK12704
phosphodiesterase; Provisional
 122-256 3.63e-04

phosphodiesterase; Provisional


Pssm-ID: 237177 [Multi-domain]  Cd Length: 520  Bit Score: 42.46  E-value: 3.63e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204  122 KKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREE-DKAEWK-KAREE--DKEWRNsMDEWRKSM 197
Cdd:PRK12704  34 KEAEEEAKRILEEAKKEAEAIKKEALLEAKEEIHKLRNEFEKELRERRNElQKLEKRlLQKEEnlDRKLEL-LEKREEEL 112

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075204  198 DEWRKSMDEWRKSMDEWRKSTDEWRKSTDERLENLLNIVRE-----ILD-VQRDMRNDLSNLTRK 256
Cdd:PRK12704 113 EKKEKELEQKQQELEKKEEELEELIEEQLQELERISGLTAEeakeiLLEkVEEEARHEAAVLIKE 177
PTZ00121 PTZ00121
MAEBL; Provisional
 120-228 3.85e-04

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 42.44  E-value: 3.85e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   120 EWKKAREE-DKAEWKKAREEDK--AEWKKAREED---KAEWKKAREED----KAEWKKAREEDKAEWKKAREEDKEWRNS 189
Cdd:PTZ00121 1611 EAKKAEEAkIKAEELKKAEEEKkkVEQLKKKEAEekkKAEELKKAEEEnkikAAEEAKKAEEDKKKAEEAKKAEEDEKKA 1690

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 19075204   190 MDEWRKSMDEWRKSmDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1691 AEALKKEAEEAKKA-EELKKKEAEEKKKAEELKKAEEEN 1728
tolA_full TIGR02794
TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the ...
 122-195 1.22e-03

TolA protein; TolA couples the inner membrane complex of itself with TolQ and TolR to the outer membrane complex of TolB and OprL (also called Pal). Most of the length of the protein consists of low-complexity sequence that may differ in both length and composition from one species to another, complicating efforts to discriminate TolA (the most divergent gene in the tol-pal system) from paralogs such as TonB. Selection of members of the seed alignment and criteria for setting scoring cutoffs are based largely conserved operon struction. //The Tol-Pal complex is required for maintaining outer membrane integrity. Also involved in transport (uptake) of colicins and filamentous DNA, and implicated in pathogenesis. Transport is energized by the proton motive force. TolA is an inner membrane protein that interacts with periplasmic TolB and with outer membrane porins ompC, phoE and lamB. [Transport and binding proteins, Other, Cellular processes, Pathogenesis]


Pssm-ID: 274303 [Multi-domain]  Cd Length: 346  Bit Score: 40.21  E-value: 1.22e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19075204   122 KKAREEDKAEWKKAREEDKAEWKKAREedkAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRK 195
Cdd:TIGR02794 158 AKAAAEAKKKAEEAKKKAEAEAKAKAE---AEAKAKAEEAKAKAEAAKAKAAAEAAAKAEAEAAAAAAAEAERK 228
PTZ00121 PTZ00121
MAEBL; Provisional
 120-256 1.38e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.89  E-value: 1.38e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   120 EWKKAREEDKaewKKAREEDKAEWKKaREEDKAEWKKAREEDKAE-WKKAREEDKAEWKKAREEDKEWRNSMDEWRKSMD 198
Cdd:PTZ00121 1665 EEAKKAEEDK---KKAEEAKKAEEDE-KKAAEALKKEAEEAKKAEeLKKKEAEEKKKAEELKKAEEENKIKAEEAKKEAE 1740

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19075204   199 EWRKSMDEWRKSMDEWRK---STDEWRKSTDERLENLLNIVREILDVQRDMRNDLSNLTRK 256
Cdd:PTZ00121 1741 EDKKKAEEAKKDEEEKKKiahLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDKKIK 1801
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 1.80e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 40.51  E-value: 1.80e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREE-DKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKA--EWKKAREEDKAEWKKAREEDK---EWRN 188
Cdd:PTZ00121 1236 KKDAEEAKKAEEErNNEEIRKFEEARMAHFARRQAAIKAEEARKADELKKaeEKKKADEAKKAEEKKKADEAKkkaEEAK 1315

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|
gi 19075204   189 SMDEWRKSMDEWRKSMDEWRKSMDEwRKSTDEWRKSTDER 228
Cdd:PTZ00121 1316 KADEAKKKAEEAKKKADAAKKKAEE-AKKAAEAAKAEAEA 1354
PTZ00121 PTZ00121
MAEBL; Provisional
 39-238 3.27e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.74  E-value: 3.27e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204    39 AAKKKLLELERKALE-DKEKNLNFVVESERTLFNSKKRAFDNDECYNDRCKlfrgiVNEWGRSERTLDSLDEppawfRRE 117
Cdd:PTZ00121 1415 AAKKKADEAKKKAEEkKKADEAKKKAEEAKKADEAKKKAEEAKKAEEAKKK-----AEEAKKADEAKKKAEE-----AKK 1484

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   118 MGEWKKAREEDKaewKKAREEDKAEWKKAREEdkaEWKKAREEDKA-EWKKAREEDKA-EWKKAREEDKEWRNSMDEWRK 195
Cdd:PTZ00121 1485 ADEAKKKAEEAK---KKADEAKKAAEAKKKAD---EAKKAEEAKKAdEAKKAEEAKKAdEAKKAEEKKKADELKKAEELK 1558

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 19075204   196 SMDEWRKSMDEWRKSMDE--WRKSTDEWRKSTDERLENLLNIVRE 238
Cdd:PTZ00121 1559 KAEEKKKAEEAKKAEEDKnmALRKAEEAKKAEEARIEEVMKLYEE 1603
YhaN COG4717
Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];
123-269 4.31e-03

Uncharacterized conserved protein YhaN, contains AAA domain [Function unknown];


Pssm-ID: 443752 [Multi-domain]  Cd Length: 641  Bit Score: 38.98  E-value: 4.31e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204 123 KAREEDKAEWKKAREEdKAEWKKAREEDKAEWKKAREE-DKAEWKKAREEDKAEWKKAREEDKEWRNSMDEWRKSMDEWR 201
Cdd:COG4717  81 KEAEEKEEEYAELQEE-LEELEEELEELEAELEELREElEKLEKLLQLLPLYQELEALEAELAELPERLEELEERLEELR 159

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075204 202 ksmdEWRKSMDEWRKSTDEWRKSTDERLENLLNIVREILdvqRDMRNDLSNLTRKVDRMDMRLSRNNN 269
Cdd:COG4717 160 ----ELEEELEELEAELAELQEELEELLEQLSLATEEEL---QDLAEELEELQQRLAELEEELEEAQE 220
PTZ00121 PTZ00121
MAEBL; Provisional
 120-224 4.39e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 39.35  E-value: 4.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   120 EWKKAREEDKAEW-KKAREEDKAEWKKAREEDKaewKKAREEDKAEWKKAREED-----------------KAEWKKARE 181
Cdd:PTZ00121 1276 EARKADELKKAEEkKKADEAKKAEEKKKADEAK---KKAEEAKKADEAKKKAEEakkkadaakkkaeeakkAAEAAKAEA 1352

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 19075204   182 EDKEWRNSMDEWRKSMDEWRKSmdEWRKSMDEWRKSTDEWRKS 224
Cdd:PTZ00121 1353 EAAADEAEAAEEKAEAAEKKKE--EAKKKADAAKKKAEEKKKA 1393
Borrelia_P83 pfam05262
Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.
 114-238 4.58e-03

Borrelia P83/100 protein; This family consists of several Borrelia P83/P100 antigen proteins.


Pssm-ID: 114011 [Multi-domain]  Cd Length: 489  Bit Score: 38.83  E-value: 4.58e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   114 FRREMGEWKKAREEDKAewKKAREEDKAEWKKAREEDKAEWKKAREEDKAEwkKAREEDKAEWKKAREEDKEWRNSMDEW 193
Cdd:pfam05262 196 FRRDMTDLKERESQEDA--KRAQQLKEELDKKQIDADKAQQKADFAQDNAD--KQRDEVRQKQQEAKNLPKPADTSSPKE 271

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*
gi 19075204   194 RKSMDEWRKSMDEwrKSMDEWRKSTDEWRKSTDERLENLLNIVRE 238
Cdd:pfam05262 272 DKQVAENQKREIE--KAQIEIKKNDEEALKAKDHKAFDLKQESKA 314
DctP COG1638
TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and ...
 100-185 6.35e-03

TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism];


Pssm-ID: 441245 [Multi-domain]  Cd Length: 329  Bit Score: 37.90  E-value: 6.35e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204 100 SERTLDSLdePP---AWFRREMgewKKAREEDKAEWKKAREEDKAEWKKA-------REEDKAEWKKAREEDKAEWKKar 169
Cdd:COG1638 241 NKDFWDSL--PPeqqAALLEAA---AEAAAYQRELARELEAEALAELKAAgvtvvelSPEDRAAFREAAKPVYDEWAE-- 313

                        90
                ....*....|....*.
gi 19075204 170 EEDKAEWKKAREEDKE 185
Cdd:COG1638 314 EVGAELLDAIRAALAK 329
rpsP PRK14521
30S ribosomal protein S16; Provisional
 120-185 8.02e-03

30S ribosomal protein S16; Provisional


Pssm-ID: 237744 [Multi-domain]  Cd Length: 186  Bit Score: 37.06  E-value: 8.02e-03
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19075204  120 EWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKE 185
Cdd:PRK14521 105 AWKEEKEGKVNAKKDKLSKAKKAAKKAALEAEKKVNEARAEAVAEKKAAEAAAVAAEEAAAAEEEE 170
PTZ00121 PTZ00121
MAEBL; Provisional
 115-228 8.41e-03

MAEBL; Provisional


Pssm-ID: 173412 [Multi-domain]  Cd Length: 2084  Bit Score: 38.20  E-value: 8.41e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075204   115 RREMGEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKA----EWKKAREEDKAEWKKAREEDKEWRNSM 190
Cdd:PTZ00121 1681 KKAEEDEKKAAEALKKEAEEAKKAEELKKKEAEEKKKAEELKKAEEENKikaeEAKKEAEEDKKKAEEAKKDEEEKKKIA 1760

                          90       100       110
                  ....*....|....*....|....*....|....*...
gi 19075204   191 DEWRKSMDEWRKSMDEWRKSMDEWRKSTDEWRKSTDER 228
Cdd:PTZ00121 1761 HLKKEEEKKAEEIRKEKEAVIEEELDEEDEKRRMEVDK 1798
PRK05035 PRK05035
electron transport complex protein RnfC; Provisional
 114-184 8.63e-03

electron transport complex protein RnfC; Provisional


Pssm-ID: 235334 [Multi-domain]  Cd Length: 695  Bit Score: 38.01  E-value: 8.63e-03
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19075204  114 FRREMGE-WKKAREEDKAEWKKAReedkAEWKKAREEDKAEWKKAREEDKAEWKKAREEDKAEWKKAREEDK 184
Cdd:PRK05035 431 YRQAKAEiRAIEQEKKKAEEAKAR----FEARQARLEREKAAREARHKKAAEARAAKDKDAVAAALARVKAK 498
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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