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Conserved domains on  [gi|19075513|ref|NP_588013|]
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ATPase Msp1 [Schizosaccharomyces pombe]

Protein Classification

ATP-binding protein( domain architecture ID 15329613)

ATP-binding protein with an AAA (ATPases Associated with various cellular Activities) domain, similar to vacuolar protein sorting 4 AAA-ATPase (Vps4), which recycles endosomal sorting complexes required for transport (ESCRT-III) polymers from cellular membranes

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
90-255 8.32e-108

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


:

Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 312.44  E-value: 8.32e-108
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGgLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19520   1 DIGGLDEVITELKELVILPLQRPELFDNSR-LLQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGES 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQ-SRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19520  80 QKLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATAMMKAEFMSLWDGLSTDGnCRVIVMGATNRPQDLDEAILRR 159

                ....*..
gi 19075513 249 MPKVFSI 255
Cdd:cd19520 160 MPKRFHI 166
 
Name Accession Description Interval E-value
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
90-255 8.32e-108

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 312.44  E-value: 8.32e-108
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGgLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19520   1 DIGGLDEVITELKELVILPLQRPELFDNSR-LLQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGES 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQ-SRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19520  80 QKLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATAMMKAEFMSLWDGLSTDGnCRVIVMGATNRPQDLDEAILRR 159

                ....*..
gi 19075513 249 MPKVFSI 255
Cdd:cd19520 160 MPKRFHI 166
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
57-304 5.41e-80

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 247.23  E-value: 5.41e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  57 EQVKELETLELNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGC 136
Cdd:COG1222  46 PALLLNDANLTQKRLGTPRGTAVPAESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYG--IEPPKGVLLYGPPGT 123
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 137 GKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR---------QRTdhea 207
Cdd:COG1222 124 GKTLLAKAVAGELGAPFIRVRGSELVSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRtddgtsgevQRT---- 199
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 208 MAQIKAEfMSMWDGLlsgqSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGV 285
Cdd:COG1222 200 VNQLLAE-LDGFESR----GDVLIIAATNRPDLLDPALLRpgRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKL 274
                       250
                ....*....|....*....
gi 19075513 286 VNATAGLSGSYIKEVCRSA 304
Cdd:COG1222 275 AKLTEGFSGADLKAIVTEA 293
cell_div_CdvC NF041006
cell division protein CdvC;
35-340 3.81e-57

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 189.95  E-value: 3.81e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   35 PYRQKRQDTVSKSRKRLdewagEQVKELETLE--LNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYP 112
Cdd:NF041006  52 PLRHAYEQMINEYKKRI-----EVLEELVPAEpaGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRP 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  113 EVFDthgglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKL-----EPTI 187
Cdd:NF041006 127 DLFP-----LGWPRGILLYGPPGCGKTMLAAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKskeegKPAI 201
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  188 IFIDEIDTFLRQRQrTDHEAMAQIKAEFMSMWDGLL--SGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAEQRRK 265
Cdd:NF041006 202 IFIDEIDALLGVYS-SEVGGEVRVRNQFLKEMDGLQdkSENYHVYVIGATNKPWRLDEPFLRRFQKRIYIPLPDREQRLE 280
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513  266 ILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRELFDKhgndleaikydiQSGGLRSLKTEDF 340
Cdd:NF041006 281 LLKYYTSKIKLENDVDLDELAEMTEGYTASDIRDIVQAAHMRVVKEMFEK------------GLGEPRPITMEDF 343
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
79-304 1.22e-56

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 188.89  E-value: 1.22e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   79 VLPSEID-------------VSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKAL 145
Cdd:PRK03992 108 VLPSEKDprvqameviespnVTYEDIGGLEEQIREVREAVELPLKKPELFEEVG--IEPPKGVLLYGPPGTGKTLLAKAV 185
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  146 AKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR-----------QRTdheaMAQIKAE 214
Cdd:PRK03992 186 AHETNATFIRVVGSELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRtdsgtsgdrevQRT----LMQLLAE 261
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  215 fMsmwDGLlsgQSR--VLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATA 290
Cdd:PRK03992 262 -M---DGF---DPRgnVKIIAATNRIDILDPAILRpgRFDRIIEVPLPDEEGRLEILKIHTRKMNLADDVDLEELAELTE 334
                        250
                 ....*....|....
gi 19075513  291 GLSGSYIKEVCRSA 304
Cdd:PRK03992 335 GASGADLKAICTEA 348
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
128-257 3.45e-50

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 163.92  E-value: 3.45e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEA 207
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 19075513   208 MAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPL 257
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
57-349 4.27e-49

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 175.48  E-value: 4.27e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    57 EQVKELETLELNEYEqivASQLVLPSEI--------DVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGL 128
Cdd:TIGR01243 416 EVLKELKVTMKDFME---ALKMVEPSAIrevlvevpNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMG--IRPPKGV 490
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   129 LLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAM 208
Cdd:TIGR01243 491 LLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPARGARFDTSV 570
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   209 A-QIKAEFMSMWDGLLSgQSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGV 285
Cdd:TIGR01243 571 TdRIVNQLLTEMDGIQE-LSNVVVIAATNRPDILDPALLRpgRFDRLILVPPPDEEARKEIFKIHTRSMPLAEDVDLEEL 649
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513   286 VNATAGLSGSYIKEVCR-SALSVPRRELFDKHGNDLEAIKYDIqsggLRSLKTEDFYHYESLQNV 349
Cdd:TIGR01243 650 AEMTEGYTGADIEAVCReAAMAALRESIGSPAKEKLEVGEEEF----LKDLKVEMRHFLEALKKV 710
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
125-249 7.86e-18

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 79.34  E-value: 7.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    125 PKGLLLYGPPGCGKTMLAKALAKQSQATFINV-----------------SVGLLTDKWFGESNKLVDALFTLARKLEPTI 187
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGViyidgedileevldqllLIIVGGKKASGSGELRLRLALALARKLKPDV 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19075513    188 IFIDEIDTFLRQRQRtdheamAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRM 249
Cdd:smart00382  82 LILDEITSLLDAEQE------ALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRRR 137
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
128-148 3.00e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 38.61  E-value: 3.00e-03
                         10        20
                 ....*....|....*....|.
gi 19075513  128 LLLYGPPGCGKTMLAKALAKQ 148
Cdd:NF038214  93 VLLLGPPGTGKTHLAIALGYA 113
 
Name Accession Description Interval E-value
RecA-like_ATAD1 cd19520
ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ...
90-255 8.32e-108

ATPase domain of ATPase family AAA domain-containing protein 1 and similar ATPase domains; ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase) is an ATPase that plays a critical role in regulating the surface expression of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors, thereby regulating synaptic plasticity, learning and memory. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410928 [Multi-domain]  Cd Length: 166  Bit Score: 312.44  E-value: 8.32e-108
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGgLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19520   1 DIGGLDEVITELKELVILPLQRPELFDNSR-LLQPPKGVLLYGPPGCGKTMLAKATAKEAGARFINLQVSSLTDKWYGES 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQ-SRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19520  80 QKLVAAVFSLASKLQPSIIFIDEIDSFLRQRSSTDHEATAMMKAEFMSLWDGLSTDGnCRVIVMGATNRPQDLDEAILRR 159

                ....*..
gi 19075513 249 MPKVFSI 255
Cdd:cd19520 160 MPKRFHI 166
RPT1 COG1222
ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein ...
57-304 5.41e-80

ATP-dependent 26S proteasome regulatory subunit [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440835 [Multi-domain]  Cd Length: 326  Bit Score: 247.23  E-value: 5.41e-80
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  57 EQVKELETLELNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGC 136
Cdd:COG1222  46 PALLLNDANLTQKRLGTPRGTAVPAESPDVTFDDIGGLDEQIEEIREAVELPLKNPELFRKYG--IEPPKGVLLYGPPGT 123
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 137 GKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR---------QRTdhea 207
Cdd:COG1222 124 GKTLLAKAVAGELGAPFIRVRGSELVSKYIGEGARNVREVFELAREKAPSIIFIDEIDAIAARRtddgtsgevQRT---- 199
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 208 MAQIKAEfMSMWDGLlsgqSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGV 285
Cdd:COG1222 200 VNQLLAE-LDGFESR----GDVLIIAATNRPDLLDPALLRpgRFDRVIEVPLPDEEAREEILKIHLRDMPLADDVDLDKL 274
                       250
                ....*....|....*....
gi 19075513 286 VNATAGLSGSYIKEVCRSA 304
Cdd:COG1222 275 AKLTEGFSGADLKAIVTEA 293
RecA-like_VPS4-like cd19509
ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This ...
91-255 2.51e-70

ATPase domain of VPS4, ATAD1, K, KTNA1, Spastin, FIGL-1 and similar ATPase domains; This subfamily includes the ATPase domains of vacuolar protein sorting-associated protein 4 (VPS4), ATPase family AAA domain-containing protein 1 (ATAD1, also known as Thorase), Katanin p60 ATPase-containing subunit A1 (KTNA1), Spastin, and Fidgetin-Like 1 (FIGL-1). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410917 [Multi-domain]  Cd Length: 163  Bit Score: 216.83  E-value: 2.51e-70
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  91 IGGMDEhVNQLLQD-VLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19509   1 IAGLDD-AKEALKEaVILPSLRPDLFP---GLRGPPRGILLYGPPGTGKTLLARAVASESGSTFFSISASSLVSKWVGES 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQS-RVLVLGATNRPADIDEAIRRR 248
Cdd:cd19509  77 EKIVRALFALARELQPSIIFIDEIDSLLSERGSGEHEASRRVKTEFLVQMDGVLNKPEdRVLVLGATNRPWELDEAFLRR 156

                ....*..
gi 19075513 249 MPKVFSI 255
Cdd:cd19509 157 FEKRIYI 163
SpoVK COG0464
AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle ...
29-304 6.08e-69

AAA+-type ATPase, SpoVK/Ycf46/Vps4 family [Cell wall/membrane/envelope biogenesis, Cell cycle control, cell division, chromosome partitioning, Signal transduction mechanisms];


Pssm-ID: 440232 [Multi-domain]  Cd Length: 397  Bit Score: 221.32  E-value: 6.08e-69
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  29 LLSTLDPYRQKRQDTVSKSRKRLDEWAGEQVKELETLELNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFP 108
Cdd:COG0464  97 LLLLLLLLLLLLLLLLDLERALLELLRESAEALALAAPLVTYEDIGGLEEELLELREAILDDLGGLEEVKEELRELVALP 176
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 109 LKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTII 188
Cdd:COG0464 177 LKRPELREEYG--LPPPRGLLLYGPPGTGKTLLARALAGELGLPLIEVDLSDLVSKYVGETEKNLREVFDKARGLAPCVL 254
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 189 FIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLlsgQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAEQRRKILE 268
Cdd:COG0464 255 FIDEADALAGKRGEVGDGVGRRVVNTLLTEMEEL---RSDVVVIAATNRPDLLDPALLRRFDEIIFFPLPDAEERLEIFR 331
                       250       260       270
                ....*....|....*....|....*....|....*.
gi 19075513 269 LYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSA 304
Cdd:COG0464 332 IHLRKRPLDEDVDLEELAEATEGLSGADIRNVVRRA 367
cell_div_CdvC NF041006
cell division protein CdvC;
35-340 3.81e-57

cell division protein CdvC;


Pssm-ID: 468935 [Multi-domain]  Cd Length: 371  Bit Score: 189.95  E-value: 3.81e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   35 PYRQKRQDTVSKSRKRLdewagEQVKELETLE--LNEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYP 112
Cdd:NF041006  52 PLRHAYEQMINEYKKRI-----EVLEELVPAEpaGPDVEKESDEELVVKEKPKVTFSDIVGLEDVKEALKEAIVYPSKRP 126
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  113 EVFDthgglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKL-----EPTI 187
Cdd:NF041006 127 DLFP-----LGWPRGILLYGPPGCGKTMLAAAVANEIDSEFIHVDAASIMSKWLGEAEKNVAKIFKKAREKskeegKPAI 201
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  188 IFIDEIDTFLRQRQrTDHEAMAQIKAEFMSMWDGLL--SGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAEQRRK 265
Cdd:NF041006 202 IFIDEIDALLGVYS-SEVGGEVRVRNQFLKEMDGLQdkSENYHVYVIGATNKPWRLDEPFLRRFQKRIYIPLPDREQRLE 280
                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513  266 ILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRELFDKhgndleaikydiQSGGLRSLKTEDF 340
Cdd:NF041006 281 LLKYYTSKIKLENDVDLDELAEMTEGYTASDIRDIVQAAHMRVVKEMFEK------------GLGEPRPITMEDF 343
PRK03992 PRK03992
proteasome-activating nucleotidase; Provisional
79-304 1.22e-56

proteasome-activating nucleotidase; Provisional


Pssm-ID: 179699 [Multi-domain]  Cd Length: 389  Bit Score: 188.89  E-value: 1.22e-56
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   79 VLPSEID-------------VSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKAL 145
Cdd:PRK03992 108 VLPSEKDprvqameviespnVTYEDIGGLEEQIREVREAVELPLKKPELFEEVG--IEPPKGVLLYGPPGTGKTLLAKAV 185
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  146 AKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR-----------QRTdheaMAQIKAE 214
Cdd:PRK03992 186 AHETNATFIRVVGSELVQKFIGEGARLVRELFELAREKAPSIIFIDEIDAIAAKRtdsgtsgdrevQRT----LMQLLAE 261
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  215 fMsmwDGLlsgQSR--VLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATA 290
Cdd:PRK03992 262 -M---DGF---DPRgnVKIIAATNRIDILDPAILRpgRFDRIIEVPLPDEEGRLEILKIHTRKMNLADDVDLEELAELTE 334
                        250
                 ....*....|....
gi 19075513  291 GLSGSYIKEVCRSA 304
Cdd:PRK03992 335 GASGADLKAICTEA 348
RecA-like_spastin cd19524
ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in ...
90-251 1.52e-55

ATPase domain of spastin; Spastin is an ATP-dependent microtubule-severing protein involved in microtubule dynamics; it specifically recognizes and cuts microtubules that are polyglutamylated. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410932 [Multi-domain]  Cd Length: 164  Bit Score: 178.89  E-value: 1.52e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19524   1 DIAGQDLAKQALQEMVILPSLRPELFT---GLRAPARGLLLFGPPGNGKTMLAKAVAAESNATFFNISAASLTSKYVGEG 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLS-GQSRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19524  78 EKLVRALFAVARELQPSIIFIDEVDSLLSERSEGEHEASRRLKTEFLIEFDGVQSnGDDRVLVMGATNRPQELDDAVLRR 157

                ...
gi 19075513 249 MPK 251
Cdd:cd19524 158 FTK 160
RecA-like_Figl-1 cd19525
ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; ...
85-255 2.74e-55

ATPase domain of Fidgetin-Like 1 (FIGL-1); FIGL-1 may participate in DNA repair in the nucleus; it may be involved in DNA double-strand break repair via homologous recombination. Caenorhabditis elegans FIGL-1 is a nuclear protein and controls the mitotic progression in the germ line and mouse FIGL-1 may be involved in the control of male meiosis. human FIGL-1 has been shown to be a centrosome protein involved in ciliogenesis perhaps as a microtubule-severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410933 [Multi-domain]  Cd Length: 186  Bit Score: 179.03  E-value: 2.74e-55
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  85 DVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDK 164
Cdd:cd19525  18 PINWADIAGLEFAKKTIKEIVVWPMLRPDIFT---GLRGPPKGILLFGPPGTGKTLIGKCIASQSGATFFSISASSLTSK 94
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 165 WFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGL-LSGQSRVLVLGATNRPADIDE 243
Cdd:cd19525  95 WVGEGEKMVRALFSVARCKQPAVIFIDEIDSLLSQRGEGEHESSRRIKTEFLVQLDGAtTSSEDRILVVGATNRPQEIDE 174
                       170
                ....*....|..
gi 19075513 244 AIRRRMPKVFSI 255
Cdd:cd19525 175 AARRRLVKRLYI 186
COG1223 COG1223
Predicted ATPase, AAA+ superfamily [General function prediction only];
88-306 5.28e-52

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440836 [Multi-domain]  Cd Length: 246  Bit Score: 172.76  E-value: 5.28e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  88 FDDIGGMDEhVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFG 167
Cdd:COG1223   1 LDDVVGQEE-AKKKLKLIIKELRRRENLRKFG--LWPPRKILFYGPPGTGKTMLAEALAGELKLPLLTVRLDSLIGSYLG 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 168 ESNKLVDALFTLARKlEPTIIFIDEIDTFLRQRQRT-DHEAMAQIKAEFMSMWDGLlsgQSRVLVLGATNRPADIDEAIR 246
Cdd:COG1223  78 ETARNLRKLFDFARR-APCVIFFDEFDAIAKDRGDQnDVGEVKRVVNALLQELDGL---PSGSVVIAATNHPELLDSALW 153
                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 247 RRMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALS 306
Cdd:COG1223 154 RRFDEVIEFPLPDKEERKEILELNLKKFPLPFELDLKKLAKKLEGLSGADIEKVLKTALK 213
RecA-like_CDC48_NLV2_r1-like cd19503
first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and ...
90-247 7.13e-52

first of two ATPase domains of CDC48 and NLV2, and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. This subfamily also includes the first of the two ATPase domains of NVL (nuclear VCP-like protein) 2, an isoform of NVL mainly present in the nucleolus, which is involved in ribosome biogenesis, in telomerase assembly and the regulation of telomerase activity, and in pre-rRNA processing. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410911 [Multi-domain]  Cd Length: 165  Bit Score: 169.78  E-value: 7.13e-52
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19503   1 DIGGLDEQIASLKELIELPLKYPELFRALG--LKPPRGVLLHGPPGTGKTLLARAVANEAGANFLSISGPSIVSKYLGES 78
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDEAIRR 247
Cdd:cd19503  79 EKNLREIFEEARSHAPSIIFIDEIDALAPKREEDQREVERRVVAQLLTLMDG-MSSRGKVVVIAATNRPDAIDPALRR 155
AAA pfam00004
ATPase family associated with various cellular activities (AAA); AAA family proteins often ...
128-257 3.45e-50

ATPase family associated with various cellular activities (AAA); AAA family proteins often perform chaperone-like functions that assist in the assembly, operation, or disassembly of protein complexes.


Pssm-ID: 459627 [Multi-domain]  Cd Length: 130  Bit Score: 163.92  E-value: 3.45e-50
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEA 207
Cdd:pfam00004   1 LLLYGPPGTGKTTLAKAVAKELGAPFIEISGSELVSKYVGESEKRLRELFEAAKKLAPCVIFIDEIDALAGSRGSGGDSE 80
                          90       100       110       120       130
                  ....*....|....*....|....*....|....*....|....*....|
gi 19075513   208 MAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPL 257
Cdd:pfam00004  81 SRRVVNQLLTELDGFTSSNSKVIVIAATNRPDKLDPALLGRFDRIIEFPL 130
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
57-349 4.27e-49

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 175.48  E-value: 4.27e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    57 EQVKELETLELNEYEqivASQLVLPSEI--------DVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGL 128
Cdd:TIGR01243 416 EVLKELKVTMKDFME---ALKMVEPSAIrevlvevpNVRWSDIGGLEEVKQELREAVEWPLKHPEIFEKMG--IRPPKGV 490
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   129 LLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAM 208
Cdd:TIGR01243 491 LLFGPPGTGKTLLAKAVATESGANFIAVRGPEILSKWVGESEKAIREIFRKARQAAPAIIFFDEIDAIAPARGARFDTSV 570
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   209 A-QIKAEFMSMWDGLLSgQSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGV 285
Cdd:TIGR01243 571 TdRIVNQLLTEMDGIQE-LSNVVVIAATNRPDILDPALLRpgRFDRLILVPPPDEEARKEIFKIHTRSMPLAEDVDLEEL 649
                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513   286 VNATAGLSGSYIKEVCR-SALSVPRRELFDKHGNDLEAIKYDIqsggLRSLKTEDFYHYESLQNV 349
Cdd:TIGR01243 650 AEMTEGYTGADIEAVCReAAMAALRESIGSPAKEKLEVGEEEF----LKDLKVEMRHFLEALKKV 710
CDC48 TIGR01243
AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two ...
85-349 2.19e-48

AAA family ATPase, CDC48 subfamily; This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.


Pssm-ID: 273521 [Multi-domain]  Cd Length: 733  Bit Score: 173.55  E-value: 2.19e-48
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    85 DVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDK 164
Cdd:TIGR01243 174 KVTYEDIGGLKEAKEKIREMVELPMKHPELFEHLG--IEPPKGVLLYGPPGTGKTLLAKAVANEAGAYFISINGPEIMSK 251
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   165 WFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDEA 244
Cdd:TIGR01243 252 YYGESEERLREIFKEAEENAPSIIFIDEIDAIAPKREEVTGEVEKRVVAQLLTLMDG-LKGRGRVIVIGATNRPDALDPA 330
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   245 IRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRELFDKHGNDLEA 322
Cdd:TIGR01243 331 LRRpgRFDREIVIRVPDKRARKEILKVHTRNMPLAEDVDLDKLAEVTHGFVGADLAALAKEAAMAALRRFIREGKINFEA 410
                         250       260
                  ....*....|....*....|....*....
gi 19075513   323 ikYDIQSGGLRSLKT--EDFyhYESLQNV 349
Cdd:TIGR01243 411 --EEIPAEVLKELKVtmKDF--MEALKMV 435
RecA-like_VPS4 cd19521
ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein ...
85-251 1.52e-46

ATPase domain of vacuolar protein sorting-associated protein 4; Vacuolar protein sorting-associated protein 4 (Vps4) is believed to be involved in intracellular protein transport out of a prevacuolar endosomal compartment. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410929 [Multi-domain]  Cd Length: 170  Bit Score: 156.18  E-value: 1.52e-46
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  85 DVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDK 164
Cdd:cd19521   3 NVKWEDVAGLEGAKEALKEAVILPVKFPHLFT---GNRKPWSGILLYGPPGTGKSYLAKAVATEANSTFFSVSSSDLVSK 79
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 165 WFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEA 244
Cdd:cd19521  80 WMGESEKLVKQLFAMARENKPSIIFIDEVDSLCGTRGEGESEASRRIKTELLVQMNGVGNDSQGVLVLGATNIPWQLDSA 159

                ....*..
gi 19075513 245 IRRRMPK 251
Cdd:cd19521 160 IRRRFEK 166
RecA-like_KTNA1 cd19522
Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is ...
90-251 4.34e-45

Katanin p60 ATPase-containing subunit A1; Katanin p60 ATPase-containing subunit A1 (KTNA1) is the catalytic subunit of the Katanin complex which is severs microtubules in an ATP-dependent manner, and is implicated in multiple aspects of microtubule dynamics. In addition to the p60 catalytic ATPase subunit, Katanin contains an accessory subunit (p80 or p80-like). The microtubule-severing activity of the ATPase is essential for female meiotic spindle assembly, and male gamete production; and the katanin complex severing microtubules is under tight regulation during the transition from the meiotic to mitotic stage to allow proper embryogenesis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410930 [Multi-domain]  Cd Length: 170  Bit Score: 152.45  E-value: 4.34e-45
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19522   1 DIADLEEAKKLLEEAVVLPMWMPEFFK---GIRRPWKGVLMVGPPGTGKTLLAKAVATECGTTFFNVSSSTLTSKYRGES 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTD-HEAMAQIKAEFMSMWDGLLSGQSR------VLVLGATNRPADID 242
Cdd:cd19522  78 EKLVRLLFEMARFYAPTTIFIDEIDSICSRRGTSEeHEASRRVKSELLVQMDGVGGASENddpskmVMVLAATNFPWDID 157

                ....*....
gi 19075513 243 EAIRRRMPK 251
Cdd:cd19522 158 EALRRRLEK 166
RecA-like_CDC48_r2-like cd19511
second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase ...
99-247 4.05e-44

second of two ATPase domains of CDC48/p97, PEX1 and -6, VAT and NVL, and similar ATPase domains; This subfamily includes the second of two ATPase domains of the molecular chaperone CDC48 in yeast and p97 or VCP in metazoans, Peroxisomal biogenesis factor 1 (PEX1) and -6 (PEX6), Valosin-containing protein-like ATPase (VAT), and nuclear VCP-like protein (NVL). This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410919 [Multi-domain]  Cd Length: 159  Bit Score: 149.36  E-value: 4.05e-44
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  99 NQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFT 178
Cdd:cd19511   3 RELKEAVEWPLKHPDAFKRLG--IRPPKGVLLYGPPGCGKTLLAKALASEAGLNFISVKGPELFSKYVGESERAVREIFQ 80
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 179 LARKLEPTIIFIDEIDTFLRQR-QRTDHEAMAQIKAEFMSMWDGLLSGQSrVLVLGATNRPADIDEAIRR 247
Cdd:cd19511  81 KARQAAPCIIFFDEIDSLAPRRgQSDSSGVTDRVVSQLLTELDGIESLKG-VVVIAATNRPDMIDPALLR 149
PTZ00361 PTZ00361
26 proteosome regulatory subunit 4-like protein; Provisional
87-311 5.55e-43

26 proteosome regulatory subunit 4-like protein; Provisional


Pssm-ID: 185575 [Multi-domain]  Cd Length: 438  Bit Score: 154.16  E-value: 5.55e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   87 SFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWF 166
Cdd:PTZ00361 181 SYADIGGLEQQIQEIKEAVELPLTHPELYDDIG--IKPPKGVILYGPPGTGKTLLAKAVANETSATFLRVVGSELIQKYL 258
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  167 GESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKA---EFMSMWDGLLSgQSRVLVLGATNRPADIDE 243
Cdd:PTZ00361 259 GDGPKLVRELFRVAEENAPSIVFIDEIDAIGTKRYDATSGGEKEIQRtmlELLNQLDGFDS-RGDVKVIMATNRIESLDP 337
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  244 AIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSALSVPRRE 311
Cdd:PTZ00361 338 ALIRpgRIDRKIEFPNPDEKTKRRIFEIHTSKMTLAEDVDLEEFIMAKDELSGADIKAICTEAGLLALRE 407
RecA-like_PAN_like cd19502
proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily ...
87-247 1.75e-42

proteasome activating nucleotidase PAN and related proteasome subunits; This subfamily contains ATPase subunits of the eukaryotic 26S proteasome, and of the archaeal proteasome which carry out ATP-dependent degradation of substrates of the ubiquitin-proteasome pathway. The eukaryotic 26S proteasome consists of a proteolytic 20S core particle (CP), and a 19S regulatory particle (RP) which provides the ATP-dependence and the specificity for ubiquitinated proteins. In the archaea the RP is a homohexameric complex of proteasome-activating nucleotidase (PAN). This subfamily also includes various eukaryotic 26S subunits including, proteasome 26S subunit, ATPase 2 (PSMC2, also known as S7 and MSS1) which is a member of the 19S RP and has a chaperone like activity; and proteasome 20S subunit alpha 6 (PSMA6, also known as IOTA, p27K, and PROS27) which is a member of the 20S CP. This RecA-like_PAN subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410910 [Multi-domain]  Cd Length: 171  Bit Score: 145.56  E-value: 1.75e-42
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  87 SFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWF 166
Cdd:cd19502   1 TYEDIGGLDEQIREIREVVELPLKHPELFEELG--IEPPKGVLLYGPPGTGKTLLAKAVANHTDATFIRVVGSELVQKYI 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 167 GESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR-----------QRTDHEAMAQIkaefmsmwDGLLSgQSRVLVLGAT 235
Cdd:cd19502  79 GEGARLVRELFEMAREKAPSIIFIDEIDAIGAKRfdsgtggdrevQRTMLELLNQL--------DGFDP-RGNIKVIMAT 149
                       170
                ....*....|..
gi 19075513 236 NRPADIDEAIRR 247
Cdd:cd19502 150 NRPDILDPALLR 161
RecA-like_CDC48_r1-like cd19519
first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP ...
90-247 5.32e-41

first of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the first of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r1-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410927 [Multi-domain]  Cd Length: 166  Bit Score: 141.42  E-value: 5.32e-41
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19519   1 DIGGCRKQLAQIREMVELPLRHPELFKAIG--IKPPRGILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGES 78
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDEAIRR 247
Cdd:cd19519  79 ESNLRKAFEEAEKNAPAIIFIDEIDAIAPKREKTHGEVERRIVSQLLTLMDG-LKQRAHVIVMAATNRPNSIDPALRR 155
RecA-like_protease cd19481
proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of ...
102-248 1.63e-40

proteases similar to RecA; RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410889 [Multi-domain]  Cd Length: 158  Bit Score: 140.11  E-value: 1.63e-40
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 102 LQDVLFPLKYPEVFDTHGGLLscPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLAR 181
Cdd:cd19481   5 LREAVEAPRRGSRLRRYGLGL--PKGILLYGPPGTGKTLLAKALAGELGLPLIVVKLSSLLSKYVGESEKNLRKIFERAR 82
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 182 KLEPTIIFIDEIDTFLRQRQRT-DHEAMAQIKAEFMSMWDGLLSgQSRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19481  83 RLAPCILFIDEIDAIGRKRDSSgESGELRRVLNQLLTELDGVNS-RSKVLVIAATNRPDLLDPALLRP 149
pup_AAA TIGR03689
proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some ...
76-280 1.38e-39

proteasome ATPase; In the Actinobacteria, as shown for Mycobacterium tuberculosis, some proteins are modified by ligation between an epsilon-amino group of a lysine side chain and the C-terminal carboxylate of the ubiquitin-like protein Pup. This modification leads to protein degradation by the archaeal-like proteasome found in the Actinobacteria. Members of this protein family belong to the AAA family of ATPases and tend to be clustered with the genes for Pup, the Pup ligase PafA, and structural components of the proteasome. This protein forms hexameric rings with ATPase activity. [Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 200312 [Multi-domain]  Cd Length: 512  Bit Score: 146.39  E-value: 1.38e-39
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    76 SQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKA----LAKQSQA 151
Cdd:TIGR03689 169 EDLVLEEVPDVTYADIGGLGSQIEQIRDAVELPFLHPELYREYG--LKPPKGVLLYGPPGCGKTLIAKAvansLAARIGA 246
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   152 T------FINVSVGLLTDKWFGESNKLVDALFTLARKL----EPTIIFIDEIDTFLRQR---QRTDHEAMaqIKAEFMSM 218
Cdd:TIGR03689 247 EgggksyFLNIKGPELLNKYVGETERQIRLIFQRAREKasegRPVIVFFDEMDSLFRTRgsgVSSDVETT--VVPQLLAE 324
                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513   219 WDGlLSGQSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKK-VPLEANF 280
Cdd:TIGR03689 325 IDG-VESLDNVIVIGASNREDMIDPAILRpgRLDVKIRIERPDAEAAADIFAKYLTDdLPLPEDL 388
PTZ00454 PTZ00454
26S protease regulatory subunit 6B-like protein; Provisional
79-304 3.09e-39

26S protease regulatory subunit 6B-like protein; Provisional


Pssm-ID: 240423 [Multi-domain]  Cd Length: 398  Bit Score: 143.37  E-value: 3.09e-39
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   79 VLPSEID-------------VSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKAL 145
Cdd:PTZ00454 122 ILPPEADssiqllqmsekpdVTYSDIGGLDIQKQEIREAVELPLTCPELYEQIG--IDPPRGVLLYGPPGTGKTMLAKAV 199
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  146 AKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQR---QRTDHEAMAQIKAEFMSMWDGl 222
Cdd:PTZ00454 200 AHHTTATFIRVVGSEFVQKYLGEGPRMVRDVFRLARENAPSIIFIDEVDSIATKRfdaQTGADREVQRILLELLNQMDG- 278
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  223 LSGQSRVLVLGATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEV 300
Cdd:PTZ00454 279 FDQTTNVKVIMATNRADTLDPALLRpgRLDRKIEFPLPDRRQKRLIFQTITSKMNLSEEVDLEDFVSRPEKISAADIAAI 358

                 ....
gi 19075513  301 CRSA 304
Cdd:PTZ00454 359 CQEA 362
RecA-like_NVL_r1-like cd19518
first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
90-247 4.32e-39

first of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410926 [Multi-domain]  Cd Length: 169  Bit Score: 136.77  E-value: 4.32e-39
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19518   1 DIGGMDSTLKELCELLIHPILPPEYFQHLG--VEPPRGVLLHGPPGCGKTMLANAIAGELKVPFLKISATEIVSGVSGES 78
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLL---SGQSRVLVLGATNRPADIDEAIR 246
Cdd:cd19518  79 EEKIRELFDQAISNAPCIVFIDEIDAITPKRESAQREMERRIVSQLLTCMDELNnekTAGGPVLVIGATNRPDSLDPALR 158

                .
gi 19075513 247 R 247
Cdd:cd19518 159 R 159
RecA-like_VCP_r2 cd19529
second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ...
99-247 7.69e-38

second of two ATPase domains of Valosin-containing protein-like ATPase (VAT) and similar ATPase domains; The Valosin-containing protein-like ATPase of Thermoplasma acidophilum (VAT), is an archaeal homolog of the ubiquitous Cdc48/p97. It is a protein unfoldase that functions in concert with the 20S proteasome by unfolding proteasome substrates and passing them on for degradation. VAT forms a homohexamer, each monomer contains two tandem ATPase domains, referred to as D1 and D2, and an N-terminal domain. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410937 [Multi-domain]  Cd Length: 159  Bit Score: 133.00  E-value: 7.69e-38
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  99 NQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFT 178
Cdd:cd19529   3 QELKEAVEWPLLKPEVFKRLG--IRPPKGILLYGPPGTGKTLLAKAVATESNANFISVKGPELLSKWVGESEKAIREIFR 80
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 179 LARKLEPTIIFIDEIDTFLRQRQRT-DHEAMAQIKAEFMSMWDGLLSGQSrVLVLGATNRPADIDEAIRR 247
Cdd:cd19529  81 KARQVAPCVIFFDEIDSIAPRRGTTgDSGVTERVVNQLLTELDGLEEMNG-VVVIAATNRPDIIDPALLR 149
RecA-like_NVL_r2-like cd19530
second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL ...
100-247 1.57e-37

second of two ATPase domains of NVL (nuclear VCP-like protein) and similar ATPase domains; NVL exists in two forms with N-terminal extensions of different lengths in mammalian cells. NVL has two alternatively spliced isoforms, a short form, NVL1, and a long form, NVL2. NVL2, the major species, is mainly present in the nucleolus, whereas NVL1 is nucleoplasmic. Each has an N-terminal domain, followed by two tandem ATPase domains; this subfamily includes the first of the two ATPase domains. NVL2 is involved in the biogenesis of the 60S ribosome subunit by associating specifically with ribosome protein L5 and modulating the function of DOB1. NVL2 is also required for telomerase assembly and the regulation of telomerase activity, and is involved in pre-rRNA processing. The role of NVL1 is unclear. This RecA-like_NVL_r1-like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410938 [Multi-domain]  Cd Length: 161  Bit Score: 132.23  E-value: 1.57e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 100 QLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTL 179
Cdd:cd19530   7 ELTMSILRPIKRPDIYKALG--IDLPTGVLLYGPPGCGKTLLAKAVANESGANFISVKGPELLNKYVGESERAVRQVFQR 84
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 180 ARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDEAIRR 247
Cdd:cd19530  85 ARASAPCVIFFDEVDALVPKRGDGGSWASERVVNQLLTEMDG-LEERSNVFVIAATNRPDIIDPAMLR 151
RecA-like_Yta7-like cd19517
ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces ...
90-247 7.31e-37

ATPase domain of Saccharomyces cerevisiae Yta7 and similar ATPase domains; Saccharomyces cerevisiae Yta7 is a chromatin-associated AAA-ATPase involved in regulation of chromatin dynamics. Its human ortholog ANCCA/ATAD2 transcriptionally activates pathways of malignancy in a broad range of cancers. The RecA-like_Yta7 subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410925 [Multi-domain]  Cd Length: 170  Bit Score: 130.71  E-value: 7.31e-37
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALA------KQSQATFINVSVGLLTd 163
Cdd:cd19517   1 DIGGLSHYINQLKEMVFFPLLYPEVFAKFK--ITPPRGVLFHGPPGTGKTLMARALAaecskgGQKVSFFMRKGADCLS- 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 164 KWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDE 243
Cdd:cd19517  78 KWVGEAERQLRLLFEEAYRMQPSIIFFDEIDGLAPVRSSKQEQIHASIVSTLLALMDG-LDNRGQVVVIGATNRPDALDP 156

                ....
gi 19075513 244 AIRR 247
Cdd:cd19517 157 ALRR 160
FtsH_fam TIGR01241
ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct ...
76-304 4.01e-36

ATP-dependent metalloprotease FtsH; HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides]


Pssm-ID: 273520 [Multi-domain]  Cd Length: 495  Bit Score: 136.65  E-value: 4.01e-36
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    76 SQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFpLKYPEVFDTHGGLLscPKGLLLYGPPGCGKTMLAKALAKQSQATFIN 155
Cdd:TIGR01241  42 AKLLNEEKPKVTFKDVAGIDEAKEELMEIVDF-LKNPSKFTKLGAKI--PKGVLLVGPPGTGKTLLAKAVAGEAGVPFFS 118
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   156 VSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQR---TDHEAMAQIKAEFMSMWDGlLSGQSRVLVL 232
Cdd:TIGR01241 119 ISGSDFVEMFVGVGASRVRDLFEQAKKNAPCIIFIDEIDAVGRQRGAglgGGNDEREQTLNQLLVEMDG-FGTNTGVIVI 197
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19075513   233 GATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSA 304
Cdd:TIGR01241 198 AATNRPDVLDPALLRpgRFDRQVVVDLPDIKGREEILKVHAKNKKLAPDVDLKAVARRTPGFSGADLANLLNEA 271
RecA-like_fidgetin cd19523
ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. ...
90-255 1.08e-35

ATPase domain of fidgetin; Fidgetin (FIGN) is a ATP-dependent microtubule severing protein. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410931 [Multi-domain]  Cd Length: 163  Bit Score: 127.69  E-value: 1.08e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  90 DIGGMDEHVNQLLQDVLFPLKYPEVFDthgGLLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGES 169
Cdd:cd19523   1 DIAGLGALKAAIKEEVLWPLLRPDAFS---GLLRLPRSILLFGPRGTGKTLLGRCLASQLGATFLRLRGSTLVAKWAGEG 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 170 NKLVDALFTLARKLEPTIIFIDEIDTFLrQRQRTDHEAMAQIKAEFMSMWDGLL-SGQSRVLVLGATNRPADIDEAIRRR 248
Cdd:cd19523  78 EKILQASFLAARCRQPSVLFISDLDALL-SSQDDEASPVGRLQVELLAQLDGVLgSGEDGVLVVCTTSKPEEIDESLRRY 156

                ....*..
gi 19075513 249 MPKVFSI 255
Cdd:cd19523 157 FSKRLLV 163
RecA-like_CDC48_r2-like cd19528
second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or ...
100-247 1.26e-35

second of two ATPase domains of CDC48 and similar ATPase domains; CDC48 in yeast and p97 or VCP in metazoans is an ATP-dependent molecular chaperone which plays an essential role in many cellular processes, by segregating polyubiquitinated proteins from complexes or membranes. Cdc48/p97 consists of an N-terminal domain and two ATPase domains; this subfamily represents the second of the two ATPase domains. CDC48's roles include in the fragmentation of Golgi stacks during mitosis and for their reassembly after mitosis, and in the formation of the nuclear envelope, and of the transitional endoplasmic reticulum (tER). This RecA-like_cdc48_r2-like subfamily belongs to the RecA-like family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410936 [Multi-domain]  Cd Length: 161  Bit Score: 127.24  E-value: 1.26e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 100 QLLQDVLFPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTL 179
Cdd:cd19528   4 ELQELVQYPVEHPDKFLKFG--MTPSKGVLFYGPPGCGKTLLAKAIANECQANFISVKGPELLTMWFGESEANVRDIFDK 81
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19075513 180 ARKLEPTIIFIDEIDTFLRQR---QRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADIDEAIRR 247
Cdd:cd19528  82 ARAAAPCVLFFDELDSIAKARggnIGDAGGAADRVINQILTEMDG-MNTKKNVFIIGATNRPDIIDPAILR 151
ftsH CHL00176
cell division protein; Validated
85-295 6.89e-35

cell division protein; Validated


Pssm-ID: 214386 [Multi-domain]  Cd Length: 638  Bit Score: 134.79  E-value: 6.89e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   85 DVSFDDIGGMDEhVNQLLQDVLFPLKYPEVFDTHGGllSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDK 164
Cdd:CHL00176 179 GITFRDIAGIEE-AKEEFEEVVSFLKKPERFTAVGA--KIPKGVLLVGPPGTGKTLLAKAIAGEAEVPFFSISGSEFVEM 255
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  165 WFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQR---TDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRpADI 241
Cdd:CHL00176 256 FVGVGAARVRDLFKKAKENSPCIVFIDEIDAVGRQRGAgigGGNDEREQTLNQLLTEMDG-FKGNKGVIVIAATNR-VDI 333
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 19075513  242 -DEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGS 295
Cdd:CHL00176 334 lDAALLRpgRFDRQITVSLPDREGRLDILKVHARNKKLSPDVSLELIARRTPGFSGA 390
hflB PRK10733
ATP-dependent zinc metalloprotease FtsH;
76-318 1.53e-34

ATP-dependent zinc metalloprotease FtsH;


Pssm-ID: 182683 [Multi-domain]  Cd Length: 644  Bit Score: 134.01  E-value: 1.53e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   76 SQLVLPSEIDVSFDDIGGMDEHVNQLLQDVLFpLKYPEVFDTHGGLLscPKGLLLYGPPGCGKTMLAKALAKQSQATFIN 155
Cdd:PRK10733 139 ARMLTEDQIKTTFADVAGCDEAKEEVAELVEY-LREPSRFQKLGGKI--PKGVLMVGPPGTGKTLLAKAIAGEAKVPFFT 215
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  156 VSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQR---TDHEAMAQIKAEFMSMWDGlLSGQSRVLVL 232
Cdd:PRK10733 216 ISGSDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAglgGGHDEREQTLNQMLVEMDG-FEGNEGIIVI 294
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  233 GATNRPADIDEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATAGLSGSYIKEVCRSAlsvprr 310
Cdd:PRK10733 295 AATNRPDVLDPALLRpgRFDRQVVVGLPDVRGREQILKVHMRRVPLAPDIDAAIIARGTPGFSGADLANLVNEA------ 368

                 ....*...
gi 19075513  311 ELFDKHGN 318
Cdd:PRK10733 369 ALFAARGN 376
RecA-like_FtsH cd19501
ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc ...
86-247 6.36e-34

ATP-dependent zinc metalloprotease FtsH; FtsH ATPase is a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. It is anchored to the cytoplasmic membrane such that the amino- and carboxy-termini are exposed to the cytoplasm. It presents a membrane-bound hexameric structure that is able to unfold and degrade protein substrates. It is comprised of an N-terminal transmembrane region and the larger C-terminal cytoplasmic region, which consists of an ATPase domain and a protease domain. This RecA-Like FTsH subfamily represents the ATPase domain, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410909 [Multi-domain]  Cd Length: 171  Bit Score: 123.11  E-value: 6.36e-34
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  86 VSFDDIGGMDEHVNQLLQDVLFpLKYPEVFDTHGGLLscPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKW 165
Cdd:cd19501   1 VTFKDVAGCEEAKEELKEVVEF-LKNPEKFTKLGAKI--PKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMF 77
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 166 FGESNKLVDALFTLARKLEPTIIFIDEIDTFLRQRQRT---DHEAMAQIKAEFMSMWDGlLSGQSRVLVLGATNRPADID 242
Cdd:cd19501  78 VGVGASRVRDLFEQAKKNAPCIVFIDEIDAVGRKRGAGlggGHDEREQTLNQLLVEMDG-FESNTGVIVIAATNRPDVLD 156

                ....*
gi 19075513 243 EAIRR 247
Cdd:cd19501 157 PALLR 161
HflB COG0465
ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];
78-294 4.33e-32

ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440233 [Multi-domain]  Cd Length: 583  Bit Score: 126.30  E-value: 4.33e-32
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  78 LVLPSEIDVSFDDIGGMDEHVNQLLQDVLFpLKYPEVFDTHGGllSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVS 157
Cdd:COG0465 131 LYDEDKPKVTFDDVAGVDEAKEELQEIVDF-LKDPEKFTRLGA--KIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSIS 207
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 158 --------VGlltdkwfgesnklVDA-----LFTLARKLEPTIIFIDEIDTFLRQR-----------QRTdheaMAQIKA 213
Cdd:COG0465 208 gsdfvemfVG-------------VGAsrvrdLFEQAKKNAPCIIFIDEIDAVGRQRgaglggghderEQT----LNQLLV 270
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 214 EfmsMwDGLlSGQSRVLVLGATNRPaDI-DEAIRR--RMPKVFSIPLPNAEQRRKILELYLKKVPLEANFDWNGVVNATA 290
Cdd:COG0465 271 E---M-DGF-EGNEGVIVIAATNRP-DVlDPALLRpgRFDRQVVVDLPDVKGREAILKVHARKKPLAPDVDLEVIARRTP 344

                ....
gi 19075513 291 GLSG 294
Cdd:COG0465 345 GFSG 348
RecA-like_PEX6_r2 cd19527
second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as ...
100-247 1.63e-27

second of two ATPase domains of Peroxisomal biogenesis factor 6 (PEX6); PEX6(also known as Peroxin61)/PEX1 is a protein unfoldase; PEX6 and PEX1 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. This subfamily represents the second ATPase domain of PEX6. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410935 [Multi-domain]  Cd Length: 160  Bit Score: 105.67  E-value: 1.63e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 100 QLLQDVLFPLKYPEVFDTHGGLLScpkGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTL 179
Cdd:cd19527   4 EILDTIQLPLEHPELFSSGLRKRS---GILLYGPPGTGKTLLAKAIATECSLNFLSVKGPELINMYIGESEANVREVFQK 80
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 180 ARKLEPTIIFIDEIDTFLRQRQRTDHEA--MAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRR 247
Cdd:cd19527  81 ARDAKPCVIFFDELDSLAPSRGNSGDSGgvMDRVVSQLLAELDGMSSSGQDVFVIGATNRPDLLDPALLR 150
RecA-like_PEX1_r2 cd19526
second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as ...
98-247 3.34e-27

second of two ATPase domains of Peroxisomal biogenesis factor 1 (PEX1); PEX1(also known as Peroxin-1)/PEX6 is a protein unfoldase; PEX1 and PEX6 form a heterohexameric Type-2 AAA-ATPase complex and are essential for peroxisome biogenesis as they are required for the import of folded proteins into the peroxisomal matrix. PEX-1 is required for stability of PEX5. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410934 [Multi-domain]  Cd Length: 158  Bit Score: 104.82  E-value: 3.34e-27
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  98 VNQLLQDVL-FPLKYPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDAL 176
Cdd:cd19526   1 VKKALEETIeWPSKYPKIFASSP--LRLRSGILLYGPPGCGKTLLASAIASECGLNFISVKGPELLNKYIGASEQNVRDL 78
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19075513 177 FTLARKLEPTIIFIDEIDTFLRQRQRTDHEAMAQIKAEFMSMWDGLLSGQSrVLVLGATNRPADIDEAIRR 247
Cdd:cd19526  79 FSRAQSAKPCILFFDEFDSIAPKRGHDSTGVTDRVVNQLLTQLDGVEGLDG-VYVLAATSRPDLIDPALLR 148
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
125-257 4.43e-23

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 93.75  E-value: 4.43e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 125 PKGLLLYGPPGCGKTMLAKALAKQS---QATFINVSVGLLTDKWFGES---NKLVDALFTLARKLEPTIIFIDEIDTFLR 198
Cdd:cd00009  19 PKNLLLYGPPGTGKTTLARAIANELfrpGAPFLYLNASDLLEGLVVAElfgHFLVRLLFELAEKAKPGVLFIDEIDSLSR 98
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19075513 199 QRQRTDHEAMAQIKaefmsmwdGLLSGQSRVLVLGATNRP--ADIDEAIRRRMPKVFSIPL 257
Cdd:cd00009  99 GAQNALLRVLETLN--------DLRIDRENVRVIGATNRPllGDLDRALYDRLDIRIVIPL 151
ycf46 CHL00195
Ycf46; Provisional
67-300 4.12e-18

Ycf46; Provisional


Pssm-ID: 177094 [Multi-domain]  Cd Length: 489  Bit Score: 85.07  E-value: 4.12e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   67 LNEYEQIVA-SQLVLPSEIDVSFDDIGGMDEhvnqlLQDVLfpLKYPEVFDTHG---GLLScPKGLLLYGPPGCGKTMLA 142
Cdd:CHL00195 205 LEEKKQIISqTEILEFYSVNEKISDIGGLDN-----LKDWL--KKRSTSFSKQAsnyGLPT-PRGLLLVGIQGTGKSLTA 276
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  143 KALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEID-TFLRQRQRTDHEAMAQIKAEFMSmWdg 221
Cdd:CHL00195 277 KAIANDWQLPLLRLDVGKLFGGIVGESESRMRQMIRIAEALSPCILWIDEIDkAFSNSESKGDSGTTNRVLATFIT-W-- 353
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  222 LLSGQSRVLVLGATNrpaDID----EAIRR-RMPKVFSIPLPNAEQRRKILELYLKKV-PLE-ANFDWNGVVNATAGLSG 294
Cdd:CHL00195 354 LSEKKSPVFVVATAN---NIDllplEILRKgRFDEIFFLDLPSLEEREKIFKIHLQKFrPKSwKKYDIKKLSKLSNKFSG 430

                 ....*.
gi 19075513  295 SYIKEV 300
Cdd:CHL00195 431 AEIEQS 436
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
125-249 7.86e-18

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 79.34  E-value: 7.86e-18
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    125 PKGLLLYGPPGCGKTMLAKALAKQSQATFINV-----------------SVGLLTDKWFGESNKLVDALFTLARKLEPTI 187
Cdd:smart00382   2 GEVILIVGPPGSGKTTLARALARELGPPGGGViyidgedileevldqllLIIVGGKKASGSGELRLRLALALARKLKPDV 81
                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19075513    188 IFIDEIDTFLRQRQRtdheamAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADIDEAIRRRM 249
Cdd:smart00382  82 LILDEITSLLDAEQE------ALLLLLEELRLLLLLKSEKNLTVILTTNDEKDLGPALLRRR 137
RecA-like_NSF-SEC18_r1-like cd19504
first of two ATPase domains of NSF and SEC18, and similar ATPase domains; ...
91-247 9.35e-17

first of two ATPase domains of NSF and SEC18, and similar ATPase domains; N-ethylmaleimide-sensitive factor (NSF) and Saccharomyces cerevisiae Vesicular-fusion protein Sec18, key factors for eukaryotic trafficking, are ATPases and SNARE disassembly chaperones. NSF/Sec18 activate or prime SNAREs, the terminal catalysts of membrane fusion. Sec18/NSF associates with SNARE complexes through binding Sec17/alpha-SNAP. Sec18 has an N-terminal cap domain and two nucleotide-binding domains (D1 and D2) which form the two rings of the hexameric complex. The hydrolysis of ATP by D1 generates most of the energy necessary to disassemble inactive SNARE bundles, while the D2 ring binds ATP to stabilize the homohexamer. This subfamily includes the first (D1) ATPase domain of NSF/Sec18, and belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410912 [Multi-domain]  Cd Length: 177  Bit Score: 77.14  E-value: 9.35e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  91 IGGMDEHVNQLLQDV----LFPlkyPEVFDTHGglLSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVG-LLTDKW 165
Cdd:cd19504   2 IGGLDKEFSDIFRRAfasrVFP---PEIVEQLG--CKHVKGILLYGPPGTGKTLMARQIGKMLNAREPKIVNGpEILNKY 76
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 166 FGESNKLVDALFTLARKLEPT--------IIFIDEIDTFLRQR--QRTDHEAMAQIKAEFMSMWDGlLSGQSRVLVLGAT 235
Cdd:cd19504  77 VGESEANIRKLFADAEEEQRRlgansglhIIIFDEIDAICKQRgsMAGSTGVHDTVVNQLLSKIDG-VEQLNNILVIGMT 155
                       170
                ....*....|..
gi 19075513 236 NRPADIDEAIRR 247
Cdd:cd19504 156 NRKDLIDEALLR 167
RecA-like_Ycf46-like cd19507
ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of ...
122-253 2.35e-16

ATPase domain of Ycf46 and similar ATPase domains; Ycf46 may play a role in the regulation of photosynthesis in cyanobacteria, especially in CO2 uptake and utilization. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410915 [Multi-domain]  Cd Length: 161  Bit Score: 75.48  E-value: 2.35e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 122 LSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEID-TFLRQR 200
Cdd:cd19507  28 LPTPKGLLLVGIQGTGKSLTAKAIAGVWQLPLLRLDMGRLFGGLVGESESRLRQMIQTAEAIAPCVLWIDEIEkGFSNAD 107
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 201 QRTDHEAMAQIKAEFMSmWdgLLSGQSRVLVLGATNR----PAdidEAIRR-RMPKVF 253
Cdd:cd19507 108 SKGDSGTSSRVLGTFLT-W--LQEKKKPVFVVATANNvqslPP---ELLRKgRFDEIF 159
RecA-like_ATAD3-like cd19512
ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase ...
126-252 1.03e-11

ATPase domains of ATPase AAA-domain protein 3A (ATAD3A), -3B, and -3C, and similar ATPase domains; ATPase AAA-domain protein 3 (ATAD3) is a ubiquitously expressed mitochondrial protein involved in mitochondrial dynamics, DNA-nucleoid structural organization, cholesterol transport and steroidogenesis. The ATAD3 gene family in human comprises three paralog genes: ATAD3A, ATAD3B and ATAD3C. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410920 [Multi-domain]  Cd Length: 150  Bit Score: 62.16  E-value: 1.03e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 126 KGLLLYGPPGCGKTMLAKALAKQS---QATFINVSVGLLTDKWFGESNKLVDALFTLARKLeptIIFIDEIDTFLRQRQR 202
Cdd:cd19512  23 RNILFYGPPGTGKTLFAKKLALHSgmdYAIMTGGDVAPMGREGVTAIHKVFDWANTSRRGL---LLFVDEADAFLRKRST 99
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 19075513 203 TdheamaQIKAEFMSMWDGLL---SGQSR--VLVLgATNRPADIDEAIRRRMPKV 252
Cdd:cd19512 100 E------KISEDLRAALNAFLyrtGEQSNkfMLVL-ASNQPEQFDWAINDRIDEM 147
RecA-like_IQCA1 cd19506
ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein ...
126-242 3.02e-11

ATPase domain of IQ and AAA domain-containing protein 1 (IQCA1); IQCA1 (also known as dynein regulatory complex subunit 11, DRC11 and IQCA) is an ATPase subunit of the nexin-dynein regulatory complex (N-DRC). The 9 + 2 axoneme of most motile cilia and flagella consists of nine outer doublet microtubules arranged in a ring surrounding a central pair of two singlet microtubules. The N-DRC complex maintains alignment between outer doublet microtubules and limits microtubule sliding in motile axonemes. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410914 [Multi-domain]  Cd Length: 160  Bit Score: 61.00  E-value: 3.02e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 126 KGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESN--KLVDALFTLARKLEPTIIFIDEID-TFLRQRQR 202
Cdd:cd19506  27 KSLLLAGPSGVGKKMLVHAICTETGANLFNLSPSNIAGKYPGKNGlqMMLHLVLKVARQLQPSVIWIGDAEkTFYKKVPK 106
                        90       100       110       120
                ....*....|....*....|....*....|....*....|
gi 19075513 203 TDHEAMAQIKAEFMSMWDGLLSGQSRVLVLGATNRPADID 242
Cdd:cd19506 107 TEKQLDPKRLKKDLPKILKSLKPEDRVLIVGTTSRPFEAD 146
RecA-like_BCS1 cd19510
Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of ...
126-248 1.30e-09

Mitochondrial chaperone BCS1; Mitochondrial chaperone BCS1 is necessary for the assembly of mitochondrial respiratory chain complex III and plays an important role in the maintenance of mitochondrial tubular networks, respiratory chain assembly and formation of the LETM1 complex. RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410918 [Multi-domain]  Cd Length: 153  Bit Score: 56.21  E-value: 1.30e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 126 KGLLLYGPPGCGKTMLAKALAKQSQATF--INVSVGLLTDKwfgESNKLvdalftLARKLEPTIIFIDEIDTFLRQRQRT 203
Cdd:cd19510  24 RGYLLYGPPGTGKSSFIAALAGELDYDIcdLNLSEVVLTDD---RLNHL------LNTAPKQSIILLEDIDAAFESREHN 94
                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 19075513 204 DHEAMAQIK------AEFMSMWDGLLSGQSRVLVLgATNRPADIDEAIRRR 248
Cdd:cd19510  95 KKNPSAYGGlsrvtfSGLLNALDGVASSEERIVFM-TTNHIERLDPALIRP 144
RecA-like_Pch2-like cd19508
ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as ...
121-200 2.72e-09

ATPase domain of Pachytene checkpoint 2 (Pch2) and similar ATPase domains; Pch2 (known as Thyroid hormone receptor interactor 13 (TRIP13) and 16E1BP) is a key regulator of specific chromosomal events, like the control of G2/prophase processes such as DNA break formation and recombination, checkpoint signaling, and chromosome synapsis. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion


Pssm-ID: 410916 [Multi-domain]  Cd Length: 199  Bit Score: 56.30  E-value: 2.72e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 121 LLSCPKGLLLYGPPGCGKTMLAKALAKQ---------SQATFINVSVGLLTDKWFGESNKLVDALFTLARKL---EPTII 188
Cdd:cd19508  48 LITWNRLVLLHGPPGTGKTSLCKALAQKlsirlssryRYGQLIEINSHSLFSKWFSESGKLVTKMFQKIQELiddKDALV 127
                        90
                ....*....|....
gi 19075513 189 F--IDEIDTFLRQR 200
Cdd:cd19508 128 FvlIDEVESLAAAR 141
PRK13342 PRK13342
recombination factor protein RarA; Reviewed
128-197 4.52e-09

recombination factor protein RarA; Reviewed


Pssm-ID: 237355 [Multi-domain]  Cd Length: 413  Bit Score: 57.40  E-value: 4.52e-09
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513  128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKwfgESNKLVDALFTLARKLEPTIIFIDEI--------DTFL 197
Cdd:PRK13342  39 MILWGPPGTGKTTLARIIAGATDAPFEALSAVTSGVK---DLREVIEEARQRRSAGRRTILFIDEIhrfnkaqqDALL 113
RarA COG2256
Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, ...
128-197 1.07e-08

Replication-associated recombination protein RarA (DNA-dependent ATPase) [Replication, recombination and repair];


Pssm-ID: 441857 [Multi-domain]  Cd Length: 439  Bit Score: 56.22  E-value: 1.07e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQSQATFINVS-----VglltdkwfgesnKLVDALFTLARKL----EPTIIFIDEI----- 193
Cdd:COG2256  52 MILWGPPGTGKTTLARLIANATDAEFVALSavtsgV------------KDIREVIEEARERraygRRTILFVDEIhrfnk 119

                ....*..
gi 19075513 194 ---DTFL 197
Cdd:COG2256 120 aqqDALL 126
RecA-like_HslU cd19498
ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease ...
125-194 9.88e-08

ATP-dependent protease ATPase subunit HslU; HslU is a component of the ATP-dependent protease HslVU. In HslVU, HslU ATPase serves to unfold and translocate protein substrate, and the HslV protease degrades the unfolded proteins. This RecA-like_HslU subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410906 [Multi-domain]  Cd Length: 183  Bit Score: 51.61  E-value: 9.88e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 125 PKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDkwFGESNKLVDalfTLARKLEPTIIFIDEID 194
Cdd:cd19498  46 PKNILMIGPTGVGKTEIARRLAKLAGAPFIKVEATKFTE--VGYVGRDVE---SIIRDLVEGIVFIDEID 110
RecA-like_Ycf2 cd19505
ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; ...
122-193 2.70e-06

ATPase domain of plant YCF2; Ycf2 is a chloroplast ATPase which has an essential function; however, its function remains unclear. The gene encoding YCF2 is the largest known plastid gene in angiosperms and has been used to predict phylogenetic relationships. This subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410913 [Multi-domain]  Cd Length: 161  Bit Score: 46.99  E-value: 2.70e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 122 LSCPKGLLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWF--------------GESNKLVDALFTLARKLEPTI 187
Cdd:cd19505   9 LSPSKGILLIGSIETGRSYLIKSLAANSYVPLIRISLNKLLYNKPdfgnddwidgmlilKESLHRLNLQFELAKAMSPCI 88

                ....*.
gi 19075513 188 IFIDEI 193
Cdd:cd19505  89 IWIPNI 94
AAA_5 pfam07728
AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not ...
127-249 5.10e-06

AAA domain (dynein-related subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400191 [Multi-domain]  Cd Length: 135  Bit Score: 45.36  E-value: 5.10e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   127 GLLLYGPPGCGKTMLAKALAK---QSQATFINVSVGLLTDKWFGESN------KLVDALFTLARKlEPTIIFIDEI---- 193
Cdd:pfam07728   1 GVLLVGPPGTGKTELAERLAAalsNRPVFYVQLTRDTTEEDLFGRRNidpggaSWVDGPLVRAAR-EGEIAVLDEInran 79
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 19075513   194 -DTFLRQRQRTDHEamaqikaEFMSMWDG--LLSGQSRVLVLGATNRP----ADIDEAIRRRM 249
Cdd:pfam07728  80 pDVLNSLLSLLDER-------RLLLPDGGelVKAAPDGFRLIATMNPLdrglNELSPALRSRF 135
MoxR COG0714
MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway ...
128-269 8.35e-06

MoxR-like ATPase [General function prediction only]; MoxR-like ATPase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis


Pssm-ID: 440478 [Multi-domain]  Cd Length: 292  Bit Score: 46.70  E-value: 8.35e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQSQATF--INVSVGLL---------TDKWFGEsNKLV-DALFTlarklepTIIFIDEIDt 195
Cdd:COG0714  34 LLLEGVPGVGKTTLAKALARALGLPFirIQFTPDLLpsdilgtyiYDQQTGE-FEFRpGPLFA-------NVLLADEIN- 104
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 196 flrqrqRTDH-------EAMA--QIkaefmSMWDGLLSGQSRVLVLgATNRPADID------EAIRRRMPKVFSIPLPNA 260
Cdd:COG0714 105 ------RAPPktqsallEAMEerQV-----TIPGGTYKLPEPFLVI-ATQNPIEQEgtyplpEAQLDRFLLKLYIGYPDA 172

                ....*....
gi 19075513 261 EQRRKILEL 269
Cdd:COG0714 173 EEEREILRR 181
RecA-like_Lon cd19500
lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an ...
128-194 1.24e-05

lon protease homolog 2 peroxisomal; Lon protease (also known as Lon peptidase) is an evolutionarily conserved ATP-dependent serine protease, present in bacteria and eukaryotic mitochondria and peroxisomes, which mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Lon protease is both an ATP-dependent peptidase and a protein-activated ATPase. This RecA-like Lon domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410908 [Multi-domain]  Cd Length: 182  Bit Score: 45.24  E-value: 1.24e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDkwfgESN--------------KLVDALFTlARKLEPtIIFIDEI 193
Cdd:cd19500  40 LCLVGPPGVGKTSLGKSIARALGRKFVRISLGGVRD----EAEirghrrtyvgampgRIIQALKK-AGTNNP-VFLLDEI 113

                .
gi 19075513 194 D 194
Cdd:cd19500 114 D 114
TIGR02928 TIGR02928
orc1/cdc6 family replication initiation protein; Members of this protein family are found ...
83-268 2.02e-05

orc1/cdc6 family replication initiation protein; Members of this protein family are found exclusively in the archaea. This set of DNA binding proteins shows homology to the origin recognition complex subunit 1/cell division control protein 6 family in eukaryotes. Several members may be found in genome and interact with each other. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274354 [Multi-domain]  Cd Length: 365  Bit Score: 46.09  E-value: 2.02e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513    83 EIDVSFDDIGGMDEHVNQL---LQDVLfplkypevfdtHGgllSCPKGLLLYGPPGCGKTMLAKALAKQ----SQATFIN 155
Cdd:TIGR02928   9 EPDYVPDRIVHRDEQIEELakaLRPIL-----------RG---SRPSNVFIYGKTGTGKTAVTKYVMKEleeaAEDRDVR 74
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   156 VSV--------------------------------GLLTDKWFgesNKLVDALftlaRKLEPTIIFI-DEIDTFLrqrqR 202
Cdd:TIGR02928  75 VVTvyvncqildtlyqvlvelanqlrgsgeevpttGLSTSEVF---RRLYKEL----NERGDSLIIVlDEIDYLV----G 143
                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19075513   203 TDHEAMAQI-KAEFMSMWDGllsgqSRVLVLGATNRP---ADIDEAIRRR-MPKVFSIPLPNAEQRRKILE 268
Cdd:TIGR02928 144 DDDDLLYQLsRARSNGDLDN-----AKVGVIGISNDLkfrENLDPRVKSSlCEEEIIFPPYDAEELRDILE 209
YifB COG0606
Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational ...
128-145 2.39e-05

Predicted Mg-chelatase, contains ChlI-like and ATPase domains, YifB family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440371 [Multi-domain]  Cd Length: 502  Bit Score: 45.80  E-value: 2.39e-05
                        10
                ....*....|....*...
gi 19075513 128 LLLYGPPGCGKTMLAKAL 145
Cdd:COG0606 214 LLMIGPPGSGKTMLARRL 231
PRK13341 PRK13341
AAA family ATPase;
128-196 2.75e-05

AAA family ATPase;


Pssm-ID: 237354 [Multi-domain]  Cd Length: 725  Bit Score: 45.82  E-value: 2.75e-05
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19075513  128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFGESNKlvDALFTLARKLEPTIIFIDEIDTF 196
Cdd:PRK13341  55 LILYGPPGVGKTTLARIIANHTRAHFSSLNAVLAGVKDLRAEVD--RAKERLERHGKRTILFIDEVHRF 121
AAA_2 pfam07724
AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected ...
125-194 3.09e-05

AAA domain (Cdc48 subfamily); This Pfam entry includes some of the AAA proteins not detected by the pfam00004 model.


Pssm-ID: 400187 [Multi-domain]  Cd Length: 168  Bit Score: 43.72  E-value: 3.09e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   125 PKG-LLLYGPPGCGKTMLAKALAKQ---SQATFINVSVGLLTDKW--------------FGESNKLVDALftlaRKLEPT 186
Cdd:pfam07724   2 PIGsFLFLGPTGVGKTELAKALAELlfgDERALIRIDMSEYMEEHsvsrligappgyvgYEEGGQLTEAV----RRKPYS 77

                  ....*...
gi 19075513   187 IIFIDEID 194
Cdd:pfam07724  78 IVLIDEIE 85
Mg_chelatase pfam01078
Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that ...
128-145 3.28e-05

Magnesium chelatase, subunit ChlI; Magnesium-chelatase is a three-component enzyme that catalyzes the insertion of Mg2+ into protoporphyrin IX. This is the first unique step in the synthesis of (bacterio)chlorophyll. Due to this, it is thought that Mg-chelatase has an important role in channelling inter- mediates into the (bacterio)chlorophyll branch in response to conditions suitable for photosynthetic growth. ChlI and BchD have molecular weight between 38-42 kDa.


Pssm-ID: 426032 [Multi-domain]  Cd Length: 207  Bit Score: 44.45  E-value: 3.28e-05
                          10
                  ....*....|....*...
gi 19075513   128 LLLYGPPGCGKTMLAKAL 145
Cdd:pfam01078  25 LLMIGPPGSGKTMLAKRL 42
PRK04195 PRK04195
replication factor C large subunit; Provisional
125-147 5.92e-05

replication factor C large subunit; Provisional


Pssm-ID: 235250 [Multi-domain]  Cd Length: 482  Bit Score: 44.91  E-value: 5.92e-05
                         10        20
                 ....*....|....*....|...
gi 19075513  125 PKGLLLYGPPGCGKTMLAKALAK 147
Cdd:PRK04195  39 KKALLLYGPPGVGKTSLAHALAN 61
ruvB PRK00080
Holliday junction branch migration DNA helicase RuvB;
128-193 1.48e-04

Holliday junction branch migration DNA helicase RuvB;


Pssm-ID: 234619 [Multi-domain]  Cd Length: 328  Bit Score: 43.20  E-value: 1.48e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19075513  128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLtdkwfgesNKLVD--ALFTLarkLEP-TIIFIDEI 193
Cdd:PRK00080  54 VLLYGPPGLGKTTLANIIANEMGVNIRITSGPAL--------EKPGDlaAILTN---LEEgDVLFIDEI 111
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
126-148 2.05e-04

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 42.08  E-value: 2.05e-04
                        10        20
                ....*....|....*....|...
gi 19075513 126 KGLLLYGPPGCGKTMLAKALAKQ 148
Cdd:COG1484 100 ENLILLGPPGTGKTHLAIALGHE 122
AAA_33 pfam13671
AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the ...
128-256 3.92e-04

AAA domain; This family of domains contain only a P-loop motif, that is characteriztic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.


Pssm-ID: 463952 [Multi-domain]  Cd Length: 143  Bit Score: 40.37  E-value: 3.92e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQATFINVSV--------GLLTDKWFGESNKLV-DALFTLARKLE----PTIifIDeiD 194
Cdd:pfam13671   2 ILLVGLPGSGKSTLARRLLEELGAVRLSSDDerkrlfgeGRPSISYYTDATDRTyERLHELARIALragrPVI--LD--A 77
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513   195 TFLRQRQRTDHEAMAQ-----IKAEFMSMWDGLLsgQSRVLV-LGATNRPADIDEAIRRRMPKVFSIP 256
Cdd:pfam13671  78 TNLRRDERARLLALAReygvpVRIVVFEAPEEVL--RERLAArARAGGDPSDVPEEVLDRQKARFEPP 143
RecA-like_superfamily cd01120
RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 ...
128-216 4.09e-04

RecA-like_NTPases; RecA-like NTPases. This superfamily includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410865 [Multi-domain]  Cd Length: 119  Bit Score: 39.79  E-value: 4.09e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQsqatfinvsvGLLTDKWFGesnkLVDALFTLARKLE-------PTIIFIDEIDTFLRQR 200
Cdd:cd01120   1 ILITGPPGSGKTTLLLQFAEQ----------ALLSDEPVI----FISFLDTILEAIEdlieekkLDIIIIDSLSSLARAS 66
                        90
                ....*....|....*.
gi 19075513 201 QRTDHEAMAQIKAEFM 216
Cdd:cd01120  67 QGDRSSELLEDLAKLL 82
RecA-like_ClpX cd19497
ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent ...
129-194 5.20e-04

ATP-dependent Clp protease ATP-binding subunit ClpX; ClpX is a component of the ATP-dependent protease ClpXP. In ClpXP, ClpX ATPase serves to specifically recognize, unfold, and translocate protein substrates into the chamber of ClpP protease for degradation. This RecA-like_ClpX domain subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410905 [Multi-domain]  Cd Length: 251  Bit Score: 41.05  E-value: 5.20e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 129 LLYGPPGCGKTMLAKALAKqsqatFINVSVGL-----LTDK-WFGE------SNKLVDALFTLARKlEPTIIFIDEID 194
Cdd:cd19497  54 LLIGPTGSGKTLLAQTLAK-----ILDVPFAIadattLTEAgYVGEdvenilLKLLQAADYDVERA-QRGIVYIDEID 125
McrB COG1401
5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB ...
68-148 5.42e-04

5-methylcytosine-specific restriction endonuclease McrBC, GTP-binding regulatory subunit McrB [Defense mechanisms];


Pssm-ID: 441011 [Multi-domain]  Cd Length: 477  Bit Score: 41.68  E-value: 5.42e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  68 NEYEQIVASQLVLPSEIDVSFDDIGGMDEHVNQLLQDvlfplKYPEVFDTHGGLLSCPKGLLLYGPPGCGKTMLAKALAK 147
Cdd:COG1401 169 PEDLSADALAAELSAAEELYSEDLESEDDYLKDLLRE-----KFEETLEAFLAALKTKKNVILAGPPGTGKTYLARRLAE 243

                .
gi 19075513 148 Q 148
Cdd:COG1401 244 A 244
RuvB_N pfam05496
Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the ...
128-193 5.77e-04

Holliday junction DNA helicase RuvB P-loop domain; The RuvB protein makes up part of the RuvABC revolvasome which catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. Branch migration is catalyzed by the RuvB protein that is targeted to the Holliday junction by the structure specific RuvA protein. This family contains the N-terminal region of the protein.


Pssm-ID: 398900 [Multi-domain]  Cd Length: 159  Bit Score: 39.79  E-value: 5.77e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQATFINVS----------VGLLTDkwfgesnklvdalftlarkLEP-TIIFIDEI 193
Cdd:pfam05496  36 VLLYGPPGLGKTTLANIIANEMGVNIRITSgpaierpgdlAAILTN-------------------LEPgDVLFIDEI 93
COG1373 COG1373
Predicted ATPase, AAA+ superfamily [General function prediction only];
121-193 8.74e-04

Predicted ATPase, AAA+ superfamily [General function prediction only];


Pssm-ID: 440984 [Multi-domain]  Cd Length: 405  Bit Score: 41.08  E-value: 8.74e-04
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 19075513 121 LLSCPKGLLLYGPPGCGKTMLAKALAKQ-SQATFINVSVGLLTDKWFGESNKLVDALFTLARKlePTIIFIDEI 193
Cdd:COG1373  16 LLDNRKAVVITGPRQVGKTTLLKQLAKElENILYINLDDPRLRALAEEDPDDLLEALKELYPG--KTYLFLDEI 87
T7SS_EccA TIGR03922
type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the ...
128-256 8.87e-04

type VII secretion AAA-ATPase EccA; This model represents the AAA family ATPase, EccA, of the actinobacterial flavor of type VII secretion systems. Species such as Mycobacterium tuberculosis have several instances of this system per genome, designated EccA1, EccA2, etc. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 188437 [Multi-domain]  Cd Length: 557  Bit Score: 40.98  E-value: 8.87e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQ-------SQATFINVSVGLLTDKWFGESNKLVDALftLARKLEpTIIFIDEIDTFLRQR 200
Cdd:TIGR03922 315 MLFAGPPGTGKTTIARVVAKIycglgvlRKPLVREVSRADLIGQYIGESEAKTNEI--IDSALG-GVLFLDEAYTLVETG 391
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19075513   201 -QRTDHEAMAQIKAEFMSMWDgllsGQSRVLVLGATNRPA-----DIDEAIRRRMPKVFSIP 256
Cdd:TIGR03922 392 yGQKDPFGLEAIDTLLARMEN----DRDRLVVIGAGYRKDldkflEVNEGLRSRFTRVIEFP 449
Bac_DnaA pfam00308
Bacterial dnaA protein;
128-305 9.51e-04

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 40.00  E-value: 9.51e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQATFINVSVGLLTDKWFgeSNKLVDALFT-----LARKL-EPTIIFIDEIDtFLRQRQ 201
Cdd:pfam00308  37 LFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEF--LNDFVDAIRDnktnqFKEKYrNVDVLLIDDIQ-FLAGKE 113
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   202 RTDHeamaqikaEFMSMWDGLLSGQSRVLVlgATNRP----ADIDEAIRRR--MPKVFSIPLPNAEQRRKILELYLK--- 272
Cdd:pfam00308 114 GTQE--------EFFHTFNALHESGKQIVF--SSDRPpkelEELEDRLRSRfqWGLVTDIEPPDLETRLAILRKKAEaeg 183
                         170       180       190
                  ....*....|....*....|....*....|....*
gi 19075513   273 -KVPLEA-NFDWNGVVNATAGLSGSYIKEVCRSAL 305
Cdd:pfam00308 184 iEIPPEVlNFIAQRVTDNVRELEGALNRLLAYSSL 218
Kti12 COG4088
tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) ...
128-261 9.79e-04

tRNA uridine 5-carbamoylmethylation protein Kti12 (Killer toxin insensitivity protein) [Translation, ribosomal structure and biogenesis, Defense mechanisms];


Pssm-ID: 443264 [Multi-domain]  Cd Length: 179  Bit Score: 39.71  E-value: 9.79e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQSQATFINVSV-------GLLTDKWFGES--NKLV-DALFTLARK-LEPTIIFIDEiDTF 196
Cdd:COG4088   7 LILTGPPGSGKTTFAKALAQRLYAEGIAVALlhsddfrRFLVNESFPKEtyEEVVeDVRTTTADNaLDNGYSVIVD-GTF 85
                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19075513 197 LRQRQRTDHEAMAQIKAEFMSMwdgLLSGQSRVLVLGATNRPADIDEAIRRRMPKVFSIPLPNAE 261
Cdd:COG4088  86 YYRSWQRDFRNLAKHKAPIHII---YLKAPLETALRRNRERGEPIPERVIARMYRKFDKPGTKDR 147
ruvB TIGR00635
Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions ...
128-279 9.80e-04

Holliday junction DNA helicase, RuvB subunit; All proteins in this family for which functions are known are 5'-3' DNA helicases that, as part of a complex with RuvA homologs serve as a 5'-3' Holliday junction helicase. RuvA specifically binds Holliday junctions as a sandwich of two tetramers and maintains the configuration of the junction. It forms a complex with two hexameric rings of RuvB, the subunit that contains helicase activity. The complex drives ATP-dependent branch migration of the Holliday junction recombination intermediate. The endonuclease RuvC resolves junctions. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 129721 [Multi-domain]  Cd Length: 305  Bit Score: 40.36  E-value: 9.80e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQSQaTFINVSVGLLTDKwfgeSNKLVDALFTLARKlepTIIFIDEIDTFLRQRQRTDHEA 207
Cdd:TIGR00635  33 LLLYGPPGLGKTTLAHIIANEMG-VNLKITSGPALEK----PGDLAAILTNLEEG---DVLFIDEIHRLSPAVEELLYPA 104
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513   208 MAQIKAEFMsMWDGlLSGQSRVLVL------GATNRPADIDEAIRRRMPKVFSIPLPNAEQRRKILELYLKKVPLEAN 279
Cdd:TIGR00635 105 MEDFRLDIV-IGKG-PSARSVRLDLppftlvGATTRAGMLTSPLRDRFGIILRLEFYTVEELAEIVSRSAGLLNVEIE 180
RNA_helicase pfam00910
RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding ...
128-147 1.13e-03

RNA helicase; This family includes RNA helicases thought to be involved in duplex unwinding during viral RNA replication. Members of this family are found in a variety of single stranded RNA viruses.


Pssm-ID: 459992  Cd Length: 102  Bit Score: 37.97  E-value: 1.13e-03
                          10        20
                  ....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAK 147
Cdd:pfam00910   1 IWLYGPPGCGKSTLAKYLAR 20
HolB COG0470
DNA polymerase III, delta prime subunit [Replication, recombination and repair];
125-147 1.14e-03

DNA polymerase III, delta prime subunit [Replication, recombination and repair];


Pssm-ID: 440238 [Multi-domain]  Cd Length: 289  Bit Score: 40.34  E-value: 1.14e-03
                        10        20
                ....*....|....*....|...
gi 19075513 125 PKGLLLYGPPGCGKTMLAKALAK 147
Cdd:COG0470  18 PHALLLHGPPGIGKTTLALALAR 40
AAA_14 pfam13173
AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA ...
128-193 1.25e-03

AAA domain; This family of domains contain a P-loop motif that is characteriztic of the AAA superfamily.


Pssm-ID: 463799 [Multi-domain]  Cd Length: 128  Bit Score: 38.34  E-value: 1.25e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   128 LLLYGPPGCGKTMLAKALAKQ----SQATFINvsvgLLTDKWFGESNKLVDALFTLARKLEPTIIFIDEI 193
Cdd:pfam13173   5 LVITGPRQVGKTTLLLQLIKEllppENILYIN----LDDPRLLKLADFELLELFLELLYPGKTYLFLDEI 70
RecA-like_ClpB_Hsp104-like cd19499
Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and ...
128-194 1.41e-03

Chaperone protein ClpB/Hsp104 subfamily; Bacterial Caseinolytic peptidase B (ClpB) and eukaryotic Heat shock protein 104 (Hsp104) are ATP-dependent molecular chaperones and essential proteins of the heat-shock response. ClpB/Hsp104 ATPases, in concert with the DnaK/Hsp70 chaperone system, disaggregate and reactivate aggregated proteins. This RecA-like_ClpB_Hsp104_like subfamily belongs to the RecA-like NTPase family which includes the NTP binding domain of F1 and V1 H(+)ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. The RecA-like NTPase family also includes bacterial conjugation proteins and related DNA transfer proteins involved in type II and type IV secretion.


Pssm-ID: 410907 [Multi-domain]  Cd Length: 178  Bit Score: 39.08  E-value: 1.41e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAK---QSQATFINVSVGLLTDKW--------------FGESNKLVDALftlaRKLEPTIIFI 190
Cdd:cd19499  44 FLFLGPTGVGKTELAKALAEllfGDEDNLIRIDMSEYMEKHsvsrligappgyvgYTEGGQLTEAV----RRKPYSVVLL 119

                ....
gi 19075513 191 DEID 194
Cdd:cd19499 120 DEIE 123
ClpX COG1219
ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein ...
129-194 2.58e-03

ATP-dependent protease Clp, ATPase subunit ClpX [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440832 [Multi-domain]  Cd Length: 409  Bit Score: 39.26  E-value: 2.58e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 129 LLYGPPGCGKTMLAKALAKqsqatFINVS--------------VG------LLtdkwfgesnKLVDAlftlA----RKLE 184
Cdd:COG1219 113 LLIGPTGSGKTLLAQTLAR-----ILDVPfaiadattlteagyVGedveniLL---------KLLQA----AdydvEKAE 174
                        90
                ....*....|
gi 19075513 185 PTIIFIDEID 194
Cdd:COG1219 175 RGIIYIDEID 184
PRK08939 PRK08939
primosomal protein DnaI; Reviewed
59-154 2.66e-03

primosomal protein DnaI; Reviewed


Pssm-ID: 236353 [Multi-domain]  Cd Length: 306  Bit Score: 39.08  E-value: 2.66e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   59 VKELETLELNEY-EQIVASQLV----LPSEI-DVSFDDIGGMDEHVNQLLQDVL-FPLKYPEvfDTHGgllscpKGLLLY 131
Cdd:PRK08939  91 VSYLPTPEKIEAdEEKAIKKRIqsiyMPKDLlQASLADIDLDDRDRLDALMAALdFLEAYPP--GEKV------KGLYLY 162
                         90       100
                 ....*....|....*....|....*..
gi 19075513  132 GPPGCGKTML----AKALAKQSQATFI 154
Cdd:PRK08939 163 GDFGVGKSYLlaaiANELAKKGVSSTL 189
IS21_help_AAA NF038214
IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was ...
128-148 3.00e-03

IS21-like element helper ATPase IstB; This protein family model resembles PF01695, but was built to hit full-length AAA+ ATPases of IS21 family IS (insertion sequence) elements.


Pssm-ID: 439516  Cd Length: 232  Bit Score: 38.61  E-value: 3.00e-03
                         10        20
                 ....*....|....*....|.
gi 19075513  128 LLLYGPPGCGKTMLAKALAKQ 148
Cdd:NF038214  93 VLLLGPPGTGKTHLAIALGYA 113
DnaX COG2812
DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];
129-147 4.30e-03

DNA polymerase III, gamma/tau subunits [Replication, recombination and repair];


Pssm-ID: 442061 [Multi-domain]  Cd Length: 340  Bit Score: 38.63  E-value: 4.30e-03
                        10
                ....*....|....*....
gi 19075513 129 LLYGPPGCGKTMLAKALAK 147
Cdd:COG2812  36 LFTGPRGVGKTTLARILAK 54
COG2842 COG2842
Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons]; ...
129-270 5.26e-03

Bacteriophage DNA transposition protein, AAA+ family ATPase [Mobilome: prophages, transposons];


Pssm-ID: 442090 [Multi-domain]  Cd Length: 254  Bit Score: 38.01  E-value: 5.26e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 129 LLYGPPGCGKTMLAKALAKQSQ-ATFINVSVGlLTDKWF--------------GESNKLVDAlftLARKLEPTI--IFID 191
Cdd:COG2842  54 VVYGESGVGKTTAAREYANRNPnVIYVTASPS-WTSKELleelaeelgipappGTIADLRDR---ILERLAGTGrlLIID 129
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 192 EIDtflrqrqRTDHEAMAQIKAefmsMWDGLLSGqsrvLVLGATNR-PADI--DEAIRRRMPKVFSIPLPNAEQRRKILE 268
Cdd:COG2842 130 EAD-------HLKPKALEELRD----IHDETGVG----VVLIGMERlPAKLkrYEQLYSRIGFWVEFKPLSLEDVRALAE 194

                ..
gi 19075513 269 LY 270
Cdd:COG2842 195 AW 196
Lon COG0466
ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, ...
126-159 5.44e-03

ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 440234 [Multi-domain]  Cd Length: 785  Bit Score: 38.84  E-value: 5.44e-03
                        10        20        30
                ....*....|....*....|....*....|....*....
gi 19075513 126 KG--LLLYGPPGCGKTMLAKALAKqsqAT---FINVSVG 159
Cdd:COG0466 351 KGpiLCLVGPPGVGKTSLGKSIAR---ALgrkFVRISLG 386
NACHT COG5635
Predicted NTPase, NACHT family domain [Signal transduction mechanisms];
2-279 6.75e-03

Predicted NTPase, NACHT family domain [Signal transduction mechanisms];


Pssm-ID: 444362 [Multi-domain]  Cd Length: 935  Bit Score: 38.63  E-value: 6.75e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513   2 NPTTKRAIKEIVVYALAFGCSWYAAHKLLSTLDPYRQKRQDTVSKSRKRLDEWAGEQVKELETLELNEYEQIVASQLVLP 81
Cdd:COG5635  63 SRSALSAAALLARALSALLLVLLLLESLLLLLLLLLLLAEALLALLELAALLKAVLLSLSGGSDLVLLLSESDLLLALLI 142
                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513  82 SEIDVSFDDIGGMDEHVNQLLQDVLFPLKYPEVFDTHGgllscpKGLLLYGPPGCGKT----MLAKALAKQSQAT----- 152
Cdd:COG5635 143 LLLDADGLLVSLDDLYVPLNLLERIESLKRLELLEAKK------KRLLILGEPGSGKTtllrYLALELAERYLDAedpip 216
                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 153 -FINVS--------VGLLTDKWFGESNKLVDALFTLARKLEPTIIF--IDEIdtflrqRQRTDHEAMAQIKAEFMSMWDg 221
Cdd:COG5635 217 iLIELRdlaeeaslEDLLAEALEKRGGEPEDALERLLRNGRLLLLLdgLDEV------PDEADRDEVLNQLRRFLERYP- 289
                       250       260       270       280       290
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 19075513 222 llsgQSRVLVlgaTNRPADIDEAIRRRMPKVFSIPLpNAEQRRKILELYLKKVPLEAN 279
Cdd:COG5635 290 ----KARVII---TSRPEGYDSSELEGFEVLELAPL-SDEQIEEFLKKWFEATERKAE 339
ATP-synt_ab pfam00006
ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP ...
120-159 6.94e-03

ATP synthase alpha/beta family, nucleotide-binding domain; This entry includes the ATP synthase alpha and beta subunits, the ATP synthase associated with flagella and the termination factor Rho.


Pssm-ID: 425417 [Multi-domain]  Cd Length: 212  Bit Score: 37.34  E-value: 6.94e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|..
gi 19075513   120 GLLSCPKG--LLLYGPPGCGKTMLAKALAKQSQATfINVSVG 159
Cdd:pfam00006   7 GLLPIGRGqrIGIFGGSGVGKTVLAGMIARQASAD-VVVYAL 47
PRK06835 PRK06835
DNA replication protein DnaC; Validated
109-147 7.74e-03

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 37.96  E-value: 7.74e-03
                         10        20        30
                 ....*....|....*....|....*....|....*....
gi 19075513  109 LKYPEVFDTHGgllscpKGLLLYGPPGCGKTMLAKALAK 147
Cdd:PRK06835 173 KNFIENFDKNN------ENLLFYGNTGTGKTFLSNCIAK 205
COG0645 COG0645
Predicted kinase, contains AAA domain [General function prediction only];
128-210 8.28e-03

Predicted kinase, contains AAA domain [General function prediction only];


Pssm-ID: 440410 [Multi-domain]  Cd Length: 164  Bit Score: 36.81  E-value: 8.28e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 128 LLLYGPPGCGKTMLAKALAKQSQATFINvsvgllTDKW----FGE-----------SNKLVDALFTLARKL----EPTIi 188
Cdd:COG0645   2 ILVCGLPGSGKSTLARALAERLGAVRLR------SDVVrkrlFGAglaplerspeaTARTYARLLALARELlaagRSVI- 74
                        90       100
                ....*....|....*....|...
gi 19075513 189 fideID-TFLRQRQRTDHEAMAQ 210
Cdd:COG0645  75 ----LDaTFLRRAQREAFRALAE 93
ABC_ATPase cd00267
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ...
109-249 9.99e-03

ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.


Pssm-ID: 213179 [Multi-domain]  Cd Length: 157  Bit Score: 36.45  E-value: 9.99e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075513 109 LKYPEVFDTHGGLLSCPKG--LLLYGPPGCGKTMLAKALAKQSQATFINVSVGL--LTDKWFGESNKLVDALF------- 177
Cdd:cd00267   7 FRYGGRTALDNVSLTLKAGeiVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGkdIAKLPLEELRRRIGYVPqlsggqr 86
                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 19075513 178 ---TLARKL--EPTIIFIDEIDTFLRQRQRtdHEAMAQIKAefmsmwdgLLSGQSRVLVlgATNRPADIDEAIRRRM 249
Cdd:cd00267  87 qrvALARALllNPDLLLLDEPTSGLDPASR--ERLLELLRE--------LAEEGRTVII--VTHDPELAELAADRVI 151
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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