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Conserved domains on  [gi|19075910|ref|NP_588410|]
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mitochondrial 54S ribosomal protein uL22m [Schizosaccharomyces pombe]

Protein Classification

uL22m family ribosomal protein( domain architecture ID 10446401)

uL22m family ribosomal protein is a mitoribosome which binds specifically to rRNA and is important during the early stages of ribosome assembly.

Gene Ontology:  GO:0042255|GO:0003735
PubMed:  24524803

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Ribosomal_L22 pfam00237
Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and ...
 112-210 8.28e-25

Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.


:

Pssm-ID: 459725  Cd Length: 104  Bit Score: 94.39  E-value: 8.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910   112 LRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYLKKLITMG 191
Cdd:pfam00237   6 LRISPKKARLVADLIRGMSVDEALAILKFSPKKAAKIVLKLLKSAIANAENKGNLDVDNLYISEIQVDKGPTLKRIRPRA 85

                          90
                  ....*....|....*....
gi 19075910   192 RGGRAIERSPRVRVTVVLR 210
Cdd:pfam00237  86 RGRAGPIRKRTSHITVVLK 104
 
Name Accession Description Interval E-value
Ribosomal_L22 pfam00237
Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and ...
 112-210 8.28e-25

Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.


Pssm-ID: 459725  Cd Length: 104  Bit Score: 94.39  E-value: 8.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910   112 LRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYLKKLITMG 191
Cdd:pfam00237   6 LRISPKKARLVADLIRGMSVDEALAILKFSPKKAAKIVLKLLKSAIANAENKGNLDVDNLYISEIQVDKGPTLKRIRPRA 85

                          90
                  ....*....|....*....
gi 19075910   192 RGGRAIERSPRVRVTVVLR 210
Cdd:pfam00237  86 RGRAGPIRKRTSHITVVLK 104
Ribosomal_L22 cd00336
Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal ...
 105-209 1.19e-23

Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper folding and stabilizing the conformation of 23S rRNA. L22 is the largest protein contributor to the surface of the polypeptide exit channel, the tunnel through which the polypeptide product passes. L22 is also one of six proteins located at the putative translocon binding site on the exterior surface of the ribosome.


Pssm-ID: 238205  Cd Length: 105  Bit Score: 91.40  E-value: 1.19e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910 105 YTLQSMVLRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYL 184
Cdd:cd00336   1 AKAKGRYLRISPKKARLVARLIRGMSVDEALAQLEFVPKKAAKIILKLLKSAEANAENNGLDDPDKLYIKHIQVNKGPTL 80

                        90       100
                ....*....|....*....|....*
gi 19075910 185 KKLITMGRGGRAIERSPRVRVTVVL 209
Cdd:cd00336  81 KRRRPRARGRANPIRKRTCHITVVL 105
RplV COG0091
Ribosomal protein L22 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L22 ...
 112-211 4.88e-12

Ribosomal protein L22 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L22 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439861  Cd Length: 110  Bit Score: 60.83  E-value: 4.88e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910 112 LRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYLKKLITMG 191
Cdd:COG0091  10 VRISPRKARLVADLIRGKKVEEALAILEFSPKKAARIVLKVLKSAIANAENNNGLDVDNLVVKEIFVDKGPTLKRFRPRA 89

                        90       100
                ....*....|....*....|
gi 19075910 192 RGGRAIERSPRVRVTVVLRD 211
Cdd:COG0091  90 RGRATRIRKRTSHITVVVSE 109
 
Name Accession Description Interval E-value
Ribosomal_L22 pfam00237
Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and ...
 112-210 8.28e-25

Ribosomal protein L22p/L17e; This family includes L22 from prokaryotes and chloroplasts and L17 from eukaryotes.


Pssm-ID: 459725  Cd Length: 104  Bit Score: 94.39  E-value: 8.28e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910   112 LRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYLKKLITMG 191
Cdd:pfam00237   6 LRISPKKARLVADLIRGMSVDEALAILKFSPKKAAKIVLKLLKSAIANAENKGNLDVDNLYISEIQVDKGPTLKRIRPRA 85

                          90
                  ....*....|....*....
gi 19075910   192 RGGRAIERSPRVRVTVVLR 210
Cdd:pfam00237  86 RGRAGPIRKRTSHITVVLK 104
Ribosomal_L22 cd00336
Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal ...
 105-209 1.19e-23

Ribosomal protein L22/L17e. L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit. It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper folding and stabilizing the conformation of 23S rRNA. L22 is the largest protein contributor to the surface of the polypeptide exit channel, the tunnel through which the polypeptide product passes. L22 is also one of six proteins located at the putative translocon binding site on the exterior surface of the ribosome.


Pssm-ID: 238205  Cd Length: 105  Bit Score: 91.40  E-value: 1.19e-23
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910 105 YTLQSMVLRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYL 184
Cdd:cd00336   1 AKAKGRYLRISPKKARLVARLIRGMSVDEALAQLEFVPKKAAKIILKLLKSAEANAENNGLDDPDKLYIKHIQVNKGPTL 80

                        90       100
                ....*....|....*....|....*
gi 19075910 185 KKLITMGRGGRAIERSPRVRVTVVL 209
Cdd:cd00336  81 KRRRPRARGRANPIRKRTCHITVVL 105
RplV COG0091
Ribosomal protein L22 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L22 ...
 112-211 4.88e-12

Ribosomal protein L22 [Translation, ribosomal structure and biogenesis]; Ribosomal protein L22 is part of the Pathway/BioSystem: Ribosome 50S subunit


Pssm-ID: 439861  Cd Length: 110  Bit Score: 60.83  E-value: 4.88e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19075910 112 LRSSLKKVGALCRQIAHKPFYHALLQMKMSDKKISKYIATALVSARENAVREAGLDESTLYVDQIWVGKAKYLKKLITMG 191
Cdd:COG0091  10 VRISPRKARLVADLIRGKKVEEALAILEFSPKKAARIVLKVLKSAIANAENNNGLDVDNLVVKEIFVDKGPTLKRFRPRA 89

                        90       100
                ....*....|....*....|
gi 19075910 192 RGGRAIERSPRVRVTVVLRD 211
Cdd:COG0091  90 RGRATRIRKRTSHITVVVSE 109
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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