NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|19114204|ref|NP_593292|]
View 

Rho GDP dissociation inhibitor Rdi1 [Schizosaccharomyces pombe]

Protein Classification

rho GDP-dissociation inhibitor( domain architecture ID 10489308)

rho GDP-dissociation inhibitor (Rho GDI) regulates the GDP/GTP exchange reaction of the rho proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
Rho_GDI pfam02115
RHO protein GDP dissociation inhibitor;
15-202 8.25e-74

RHO protein GDP dissociation inhibitor;


:

Pssm-ID: 460449  Cd Length: 191  Bit Score: 220.96  E-value: 8.25e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    15 ELEDDTFEHGPPVSLGEKKSLNEYMKMDAEDESLQKWKASLGITGTGYSPSNDRrTVVILKLSLLVDGRDPVDVNMEDAA 94
Cdd:pfam02115   4 EAEEEEEEDSVNYKLGPQKSLKEQLELDKDDESLRRWKEQLLGAVDVADEPNEP-EVVILSLTILSPGRPDIVLPLPLTG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    95 SVEQIRKKGFTIKEGSEFKIGVKFRVQHEVISGLRYVQTVRRRGFVVDKTSTMIGSYGPSETPYDFTSEPDEAPTGMLAR 174
Cdd:pfam02115  83 DLEFKKKPWFTLKEGSEYRLKISFKVSNNIVSGLKYVQTVWKTGVKVDKTKEMLGSYSPQEEPYTYTTPEEEAPSGMFAR 162

                         170       180
                  ....*....|....*....|....*...
gi 19114204   175 GHYEANGKFVDDDKVVHHEFVWAFDVAK 202
Cdd:pfam02115 163 GSYSAKSKFVDDDKKCHLEWNWTFEIKK 190
 
Name Accession Description Interval E-value
Rho_GDI pfam02115
RHO protein GDP dissociation inhibitor;
15-202 8.25e-74

RHO protein GDP dissociation inhibitor;


Pssm-ID: 460449  Cd Length: 191  Bit Score: 220.96  E-value: 8.25e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    15 ELEDDTFEHGPPVSLGEKKSLNEYMKMDAEDESLQKWKASLGITGTGYSPSNDRrTVVILKLSLLVDGRDPVDVNMEDAA 94
Cdd:pfam02115   4 EAEEEEEEDSVNYKLGPQKSLKEQLELDKDDESLRRWKEQLLGAVDVADEPNEP-EVVILSLTILSPGRPDIVLPLPLTG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    95 SVEQIRKKGFTIKEGSEFKIGVKFRVQHEVISGLRYVQTVRRRGFVVDKTSTMIGSYGPSETPYDFTSEPDEAPTGMLAR 174
Cdd:pfam02115  83 DLEFKKKPWFTLKEGSEYRLKISFKVSNNIVSGLKYVQTVWKTGVKVDKTKEMLGSYSPQEEPYTYTTPEEEAPSGMFAR 162

                         170       180
                  ....*....|....*....|....*...
gi 19114204   175 GHYEANGKFVDDDKVVHHEFVWAFDVAK 202
Cdd:pfam02115 163 GSYSAKSKFVDDDKKCHLEWNWTFEIKK 190
 
Name Accession Description Interval E-value
Rho_GDI pfam02115
RHO protein GDP dissociation inhibitor;
15-202 8.25e-74

RHO protein GDP dissociation inhibitor;


Pssm-ID: 460449  Cd Length: 191  Bit Score: 220.96  E-value: 8.25e-74
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    15 ELEDDTFEHGPPVSLGEKKSLNEYMKMDAEDESLQKWKASLGITGTGYSPSNDRrTVVILKLSLLVDGRDPVDVNMEDAA 94
Cdd:pfam02115   4 EAEEEEEEDSVNYKLGPQKSLKEQLELDKDDESLRRWKEQLLGAVDVADEPNEP-EVVILSLTILSPGRPDIVLPLPLTG 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114204    95 SVEQIRKKGFTIKEGSEFKIGVKFRVQHEVISGLRYVQTVRRRGFVVDKTSTMIGSYGPSETPYDFTSEPDEAPTGMLAR 174
Cdd:pfam02115  83 DLEFKKKPWFTLKEGSEYRLKISFKVSNNIVSGLKYVQTVWKTGVKVDKTKEMLGSYSPQEEPYTYTTPEEEAPSGMFAR 162

                         170       180
                  ....*....|....*....|....*...
gi 19114204   175 GHYEANGKFVDDDKVVHHEFVWAFDVAK 202
Cdd:pfam02115 163 GSYSAKSKFVDDDKKCHLEWNWTFEIKK 190
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH