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Conserved domains on  [gi|19114212|ref|NP_593300|]
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anaphase-promoting complex TPR lobe subcomplex subunit Apc8 [Schizosaccharomyces pombe]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 22-154 2.90e-53

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


:

Pssm-ID: 427675  Cd Length: 140  Bit Score: 177.40  E-value: 2.90e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    22 EIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMA-------NEKLLEVEEKNIYLLA 94
Cdd:pfam04049   1 ELRAELRQAVVKCSERCLYQSAKWAAELLNGLPPPDDDDDPSDTDPDSPMSESPLPArtpnpdpEEARLEAKEYDKYLLA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    95 KSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENETLLNTNLTLSSTNRE 154
Cdd:pfam04049  81 KSYFDCKEFDRCAAVLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVNKE 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-559 1.49e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


:

Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 1.49e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 344 IGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHF 423
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 424 YALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKT 503
Cdd:COG0457  94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 19114212 504 EETEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLRELRSR 559
Cdd:COG0457 174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 254-402 6.14e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 6.14e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 254 SAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgflaqvassi 333
Cdd:COG4783  22 EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP---DEPEARLN--------------------- 77

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19114212 334 dkfrpetcsiIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVN 402
Cdd:COG4783  78 ----------LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
 
Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 22-154 2.90e-53

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


Pssm-ID: 427675  Cd Length: 140  Bit Score: 177.40  E-value: 2.90e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    22 EIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMA-------NEKLLEVEEKNIYLLA 94
Cdd:pfam04049   1 ELRAELRQAVVKCSERCLYQSAKWAAELLNGLPPPDDDDDPSDTDPDSPMSESPLPArtpnpdpEEARLEAKEYDKYLLA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    95 KSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENETLLNTNLTLSSTNRE 154
Cdd:pfam04049  81 KSYFDCKEFDRCAAVLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVNKE 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-559 1.49e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 1.49e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 344 IGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHF 423
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 424 YALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKT 503
Cdd:COG0457  94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 19114212 504 EETEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLRELRSR 559
Cdd:COG0457 174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 162-556 1.97e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.48  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   162 LESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLSIDSLETLTT-------VVSQLPSTH 234
Cdd:TIGR02917 250 ADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQayqylnqILKYAPNSH 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   235 ---------------IMTKIFYVYASHELHQVNSSA-------------YEK----LAEAEIIFPNSRYLKTQRALLTYD 282
Cdd:TIGR02917 330 qarrllasiqlrlgrVDEAIATLSPALGLDPDDPAAlsllgeaylalgdFEKaaeyLAKATELDPENAAARTQLGISKLS 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   283 SRDFDEAESLFENILtndpyRLDDMDTYSNVLFVLENkSKLGFLAQVASSIDKFR------PETCSIIGNYYSLLSEHEK 356
Cdd:TIGR02917 410 QGDPSEAIADLETAA-----QLDPELGRADLLLILSY-LRSGQFDKALAAAKKLEkkqpdnASLHNLLGAIYLGKGDLAK 483

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   357 AVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALR 436
Cdd:TIGR02917 484 AREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELN 563

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   437 PYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKAR 516
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL-----ALQPDSALAL 638

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 19114212   517 IWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLREL 556
Cdd:TIGR02917 639 LLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQL 678
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 91-533 3.13e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 59.71  E-value: 3.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    91 YLLAKSYFDCKEFERAAYTLQncKSSKSIFLRLYSKYLAG----EKKSEEENETLLNTNL-----------TLSSTNREF 155
Cdd:TIGR02917 265 YLKALVDFQKKNYEDARETLQ--DALKSAPEYLPALLLAGaseyQLGNLEQAYQYLNQILkyapnshqarrLLASIQLRL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   156 YYISEV---LESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLS----------IDSLET 222
Cdd:TIGR02917 343 GRVDEAiatLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISklsqgdpseaIADLET 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   223 LTTVVSQLPSTHIMTKIFYVyASHELHQVNSSAYE-----------------------KLAEAE-------IIFPNSRYL 272
Cdd:TIGR02917 423 AAQLDPELGRADLLLILSYL-RSGQFDKALAAAKKlekkqpdnaslhnllgaiylgkgDLAKAReafekalSIEPDFFPA 501

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   273 KTQRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKSK-LGFL------------------------- 326
Cdd:TIGR02917 502 AANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEaVAWLekaaelnpqeiepalalaqyylgkg 581

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   327 --------AQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLA 398
Cdd:TIGR02917 582 qlkkalaiLNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRA 661

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   399 VDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAlLGSQTNSSILV 478
Cdd:TIGR02917 662 LELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKA-LKRAPSSQNAI 740

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 19114212   479 RLGNLYEELQDLNSAASMYKQCIKTEeteisPETIKARIWLARWELGKKNYREAE 533
Cdd:TIGR02917 741 KLHRALLASGNTAEAVKTLEAWLKTH-----PNDAVLRTALAELYLAQKDYDKAI 790
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 254-402 6.14e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 6.14e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 254 SAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgflaqvassi 333
Cdd:COG4783  22 EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP---DEPEARLN--------------------- 77

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19114212 334 dkfrpetcsiIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVN 402
Cdd:COG4783  78 ----------LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 454-511 1.95e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.95e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 19114212 454 DRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPE 511
Cdd:cd24142  14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAI-----ELDPD 66
TPR_1 pfam00515
Tetratricopeptide repeat;
338-371 2.11e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 2.11e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 19114212   338 PETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNY 371
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 338-371 2.58e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.58e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 19114212    338 PETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNY 371
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
 
Name Accession Description Interval E-value
ANAPC8 pfam04049
Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of ...
 22-154 2.90e-53

Anaphase promoting complex subunit 8 / Cdc23; The anaphase-promoting complex is composed of eight protein subunits, including BimE (APC1), CDC27 (APC3), CDC16 (APC6), and CDC23 (APC8).


Pssm-ID: 427675  Cd Length: 140  Bit Score: 177.40  E-value: 2.90e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    22 EIRNCLLKCISECSERGLVYAVRWAAEMLNGMNPIEMEHIPFSSTPTGEFDLDPDMA-------NEKLLEVEEKNIYLLA 94
Cdd:pfam04049   1 ELRAELRQAVVKCSERCLYQSAKWAAELLNGLPPPDDDDDPSDTDPDSPMSESPLPArtpnpdpEEARLEAKEYDKYLLA 80

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    95 KSYFDCKEFERAAYTLQNCKSSKSIFLRLYSKYLAGEKKSEEENETLLNTNLTLSSTNRE 154
Cdd:pfam04049  81 KSYFDCKEFDRCAAVLKDCKSQKSLFLALYAKYLAGEKRKEEESEMVLGPQDGGNTVNKE 140
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
344-559 1.49e-28

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 113.95  E-value: 1.49e-28
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 344 IGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHF 423
Cdd:COG0457  14 LGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYE 93

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 424 YALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKT 503
Cdd:COG0457  94 EALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAA 173

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|....*.
gi 19114212 504 EETEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLRELRSR 559
Cdd:COG0457 174 ALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
365-561 3.26e-24

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 101.62  E-value: 3.26e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 365 LQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQ 444
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 445 ALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKARIWLARWEL 524
Cdd:COG0457  81 NLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERAL-----ELDPDDADALYNLGIALE 155

                       170       180       190
                ....*....|....*....|....*....|....*..
gi 19114212 525 GKKNYREAELYLSEVLNGDLELEEAKALLRELRSRME 561
Cdd:COG0457 156 KLGRYEEALELLEKLEAAALAALLAAALGEAALALAA 192
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 345-556 3.51e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 102.50  E-value: 3.51e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 345 GNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFY 424
Cdd:COG2956  15 GLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLLDR 94

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 425 ALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKte 504
Cdd:COG2956  95 AEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK-- 172

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|..
gi 19114212 505 eteISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLREL 556
Cdd:COG2956 173 ---LDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 275-543 9.43e-24

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 100.96  E-value: 9.43e-24
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 275 QRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKSKLGFLAQVASSIDKFRPETCSIIGNYYSLLSEH 354
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLERDPDRAEALLELAQDYLKAGLL 92

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 355 EKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATA 434
Cdd:COG2956  93 DRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKALK 172

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 435 LRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKTEETEIspetik 514
Cdd:COG2956 173 LDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKALELDPSDD------ 246

                       250       260
                ....*....|....*....|....*....
gi 19114212 515 ARIWLARWELGKKNYREAELYLSEVLNGD 543
Cdd:COG2956 247 LLLALADLLERKEGLEAALALLERQLRRH 275
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
330-536 3.41e-19

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 86.98  E-value: 3.41e-19
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 330 ASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAW 409
Cdd:COG0457  34 ALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEAL 113

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 410 YGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQD 489
Cdd:COG0457 114 YNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAA 193

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....*..
gi 19114212 490 LNSAASMYKQCIKTEETEISPETIKARIWLARWELGKKNYREAELYL 536
Cdd:COG0457 194 EVLLALLLALEQALRKKLAILTLAALAELLLLALALLLALRLAALAL 240
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 345-467 2.38e-17

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 85.43  E-value: 2.38e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 345 GNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFY 424
Cdd:COG3914  85 ALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEE 164

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 19114212 425 ALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAL 467
Cdd:COG3914 165 AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRAL 207
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 344-467 2.94e-17

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 78.70  E-value: 2.94e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 344 IGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHF 423
Cdd:COG4783  10 LAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKAGDYD 89

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 19114212 424 YALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAL 467
Cdd:COG4783  90 EALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKAL 133
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 255-467 9.29e-16

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 77.85  E-value: 9.29e-16
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 255 AYEKLAEAEiifPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKSKLGFLAQVASSID 334
Cdd:COG2956  64 IHQKLLERD---PDRAEALLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLG 140

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 335 KFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQ 414
Cdd:COG2956 141 PENAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAE 220

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|...
gi 19114212 415 TYEVLDMHFYALYYFQRATALRPYDqRMWQALGNCYEKIDRPQEAIKSYKRAL 467
Cdd:COG2956 221 LYEKLGDPEEALELLRKALELDPSD-DLLLALADLLERKEGLEAALALLERQL 272
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 160-504 4.47e-15

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 75.54  E-value: 4.47e-15
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 160 EVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVlkapffwsawlelslsidsletlttvvsqlpsthimtki 239
Cdd:COG2956  29 DLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLL--------------------------------------- 69

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 240 fyvyashELHQVNSSAYEKLAEAeiifpnsrYLKTQralltydsrDFDEAESLFENILTNDPYrlddmdtysnvlfvlen 319
Cdd:COG2956  70 -------ERDPDRAEALLELAQD--------YLKAG---------LLDRAEELLEKLLELDPD----------------- 108

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 320 ksklgflaqvassidkfRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAV 399
Cdd:COG2956 109 -----------------DAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIEALEKAL 171

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 400 DVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAlLGSQTNSSILVR 479
Cdd:COG2956 172 KLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKLGDPEEALELLRKA-LELDPSDDLLLA 250

                       330       340
                ....*....|....*....|....*
gi 19114212 480 LGNLYEELQDLNSAASMYKQCIKTE 504
Cdd:COG2956 251 LADLLERKEGLEAALALLERQLRRH 275
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 372-502 1.35e-14

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 70.99  E-value: 1.35e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 372 LSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYE 451
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALL 83

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|.
gi 19114212 452 KIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIK 502
Cdd:COG4783  84 KAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 390-517 7.54e-14

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 68.49  E-value: 7.54e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 390 AAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLG 469
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*...
gi 19114212 470 SQTNSSILVRLGNLYEELQDLNSAASMYKQCIKTEETEISPETIKARI 517
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAPARLLEASI 128
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 356-467 1.14e-13

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 68.11  E-value: 1.14e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 356 KAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATAL 435
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL 80

                        90       100       110
                ....*....|....*....|....*....|..
gi 19114212 436 RPYDQRMWQALGNCYEKIDRPQEAIKSYKRAL 467
Cdd:COG4235  81 DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLL 112
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 246-446 6.39e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.10  E-value: 6.39e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 246 HELHQVNSSAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgf 325
Cdd:COG3914  54 AAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALALNP---DNAEALFN------------- 117

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 326 laqvassidkfrpetcsiIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKD 405
Cdd:COG3914 118 ------------------LGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDN 179

                       170       180       190       200
                ....*....|....*....|....*....|....*....|.
gi 19114212 406 YRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQAL 446
Cdd:COG3914 180 AEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL 220
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 346-561 1.15e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 67.33  E-value: 1.15e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 346 NYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRkDYRAWYGLGQTYEVLDMHFYA 425
Cdd:COG3914   9 LAALAAAALLAAAAAAELALAAELEAAALAAALGLALLLLAALAEAAAAALLALAAGE-AAAAAAALLLLAALLELAALL 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 426 LY----------YFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAAS 495
Cdd:COG3914  88 LQalgryeealaLYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIA 167

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 19114212 496 MYKQCIkteetEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLreLRSRME 561
Cdd:COG3914 168 ALRRAL-----ELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNL--LFALRQ 226
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 407-545 1.32e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 62.52  E-value: 1.32e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 407 RAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEE 486
Cdd:COG4783   5 EALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLK 84

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*....
gi 19114212 487 LQDLNSAASMYKQCIKteeteISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLE 545
Cdd:COG4783  85 AGDYDEALALLEKALK-----LDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDPD 138
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 425-561 2.30e-11

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 61.56  E-value: 2.30e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 425 ALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkte 504
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERAL--- 78

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 19114212 505 etEISPETIKARIWLARWELGKKNYREAELYLSEVlngdLELEEAKALLRELRSRME 561
Cdd:COG4235  79 --ALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKL----LALLPADAPARLLEASIA 129
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 275-437 3.36e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 61.36  E-value: 3.36e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 275 QRALLTYDSRDFDEAESLFENILTNDPyrlddmdtysnvlfvlENKSKLGFLAQVassidkfrpetcsiignyYSLLSEH 354
Cdd:COG4783   9 ALAQALLLAGDYDEAEALLEKALELDP----------------DNPEAFALLGEI------------------LLQLGDL 54

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 355 EKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATA 434
Cdd:COG4783  55 DEAIVLLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALE 134


                ...
gi 19114212 435 LRP 437
Cdd:COG4783 135 LDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
255-494 2.01e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 61.18  E-value: 2.01e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 255 AYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgflaqvassid 334
Cdd:COG0457  27 AIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDP---DDAEALNN---------------------- 81

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 335 kfrpetcsiIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQ 414
Cdd:COG0457  82 ---------LGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGI 152

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 415 TYEVLDMHFYALYYFQRAT--ALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNS 492
Cdd:COG0457 153 ALEKLGRYEEALELLEKLEaaALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALALLLA 232


                ..
gi 19114212 493 AA 494
Cdd:COG0457 233 LR 234
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
347-437 1.16e-09

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 55.56  E-value: 1.16e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 347 YYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIEsYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYAL 426
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEAL 79

                        90
                ....*....|.
gi 19114212 427 YYFQRATALRP 437
Cdd:COG3063  80 AYLERALELDP 90
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 344-439 1.83e-09

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 55.78  E-value: 1.83e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 344 IGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHF 423
Cdd:COG4235  23 LGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNPEALYLLGLAAFQQGDYA 102

                        90
                ....*....|....*.
gi 19114212 424 YALYYFQRATALRPYD 439
Cdd:COG4235 103 EAIAAWQKLLALLPAD 118
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 162-556 1.97e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 60.48  E-value: 1.97e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   162 LESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLSIDSLETLTT-------VVSQLPSTH 234
Cdd:TIGR02917 250 ADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQayqylnqILKYAPNSH 329

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   235 ---------------IMTKIFYVYASHELHQVNSSA-------------YEK----LAEAEIIFPNSRYLKTQRALLTYD 282
Cdd:TIGR02917 330 qarrllasiqlrlgrVDEAIATLSPALGLDPDDPAAlsllgeaylalgdFEKaaeyLAKATELDPENAAARTQLGISKLS 409

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   283 SRDFDEAESLFENILtndpyRLDDMDTYSNVLFVLENkSKLGFLAQVASSIDKFR------PETCSIIGNYYSLLSEHEK 356
Cdd:TIGR02917 410 QGDPSEAIADLETAA-----QLDPELGRADLLLILSY-LRSGQFDKALAAAKKLEkkqpdnASLHNLLGAIYLGKGDLAK 483

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   357 AVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALR 436
Cdd:TIGR02917 484 AREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEAVAWLEKAAELN 563

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   437 PYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKAR 516
Cdd:TIGR02917 564 PQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLL-----ALQPDSALAL 638

                         410       420       430       440
                  ....*....|....*....|....*....|....*....|
gi 19114212   517 IWLARWELGKKNYREAELYLSEVLNGDLELEEAKALLREL 556
Cdd:TIGR02917 639 LLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQL 678
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 91-533 3.13e-09

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 59.71  E-value: 3.13e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212    91 YLLAKSYFDCKEFERAAYTLQncKSSKSIFLRLYSKYLAG----EKKSEEENETLLNTNL-----------TLSSTNREF 155
Cdd:TIGR02917 265 YLKALVDFQKKNYEDARETLQ--DALKSAPEYLPALLLAGaseyQLGNLEQAYQYLNQILkyapnshqarrLLASIQLRL 342

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   156 YYISEV---LESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKAPFFWSAWLELSLS----------IDSLET 222
Cdd:TIGR02917 343 GRVDEAiatLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISklsqgdpseaIADLET 422

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   223 LTTVVSQLPSTHIMTKIFYVyASHELHQVNSSAYE-----------------------KLAEAE-------IIFPNSRYL 272
Cdd:TIGR02917 423 AAQLDPELGRADLLLILSYL-RSGQFDKALAAAKKlekkqpdnaslhnllgaiylgkgDLAKAReafekalSIEPDFFPA 501

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   273 KTQRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKSK-LGFL------------------------- 326
Cdd:TIGR02917 502 AANLARIDIQEGNPDDAIQRFEKVLTIDPKNLRAILALAGLYLRTGNEEEaVAWLekaaelnpqeiepalalaqyylgkg 581

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   327 --------AQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLA 398
Cdd:TIGR02917 582 qlkkalaiLNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSALALLLLADAYAVMKNYAKAITSLKRA 661

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   399 VDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAlLGSQTNSSILV 478
Cdd:TIGR02917 662 LELKPDNTEAQIGLAQLLLAAKRTESAKKIAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKA-LKRAPSSQNAI 740

                         490       500       510       520       530
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 19114212   479 RLGNLYEELQDLNSAASMYKQCIKTEeteisPETIKARIWLARWELGKKNYREAE 533
Cdd:TIGR02917 741 KLHRALLASGNTAEAVKTLEAWLKTH-----PNDAVLRTALAELYLAQKDYDKAI 790
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 382-467 4.82e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 4.82e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 382 YVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIK 461
Cdd:COG5010  64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKA 143


                ....*.
gi 19114212 462 SYKRAL 467
Cdd:COG5010 144 ALQRAL 149
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 300-437 5.96e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 55.35  E-value: 5.96e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 300 DPYRLDDMDTYSNVLFVLENKSKLGFLAQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMG 379
Cdd:COG5010  16 LLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNPELYYNLA 95

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 19114212 380 HEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRP 437
Cdd:COG5010  96 LLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTSP 153
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 363-504 7.35e-09

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 54.97  E-value: 7.35e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 363 RALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEvldmhfyALYYFQRATALRPYDQRM 442
Cdd:COG5010  18 TKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEE-------SLALLEQALQLDPNNPEL 90

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 19114212 443 WQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIKTE 504
Cdd:COG5010  91 YYNLALLYSRSGDKDEAKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
345-502 4.14e-08

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 54.15  E-value: 4.14e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 345 GNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFY 424
Cdd:COG4785  80 GVAYDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYEL 159

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19114212 425 ALYYFQRATALRPYDQRMWQALGNCYEKIDrPQEAIKSYKRAllgsqtnssilvrLGNLYEELQDLNSAASMYKQCIK 502
Cdd:COG4785 160 AIADLEKALELDPNDPERALWLYLAERKLD-PEKALALLLED-------------WATAYLLQGDTEEARELFKLALA 223
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 439-562 4.36e-08

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 52.12  E-value: 4.36e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 439 DQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKARIW 518
Cdd:COG4783   3 CAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEAL-----ELDPDEPEARLN 77

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....
gi 19114212 519 LARWELGKKNYREAELYLSEVLNGDLELEEAKALLRELRSRMEH 562
Cdd:COG4783  78 LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGR 121
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
425-502 7.36e-08

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 50.17  E-value: 7.36e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 19114212 425 ALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKsYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIK 502
Cdd:COG3063  11 AEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKLDPNNAEALLNLAELLLELGDYDEALAYLERALE 87
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 389-543 5.89e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 49.57  E-value: 5.89e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 389 HAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALL 468
Cdd:COG5010   3 ALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQ 82

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19114212 469 GSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKARIWLARWELGKKNYREAELYLSEVLNGD 543
Cdd:COG5010  83 LDPNNPELYYNLALLYSRSGDKDEAKEYYEKAL-----ALSPDNPNAYSNLAALLLSLGQDDEAKAALQRALGTS 152
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
449-546 1.99e-05

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 43.24  E-value: 1.99e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 449 CYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASmYKQCIKteeteISPETIKARIWLARWELGKKN 528
Cdd:COG3063   1 LYLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALK-----LDPNNAEALLNLAELLLELGD 74

                        90
                ....*....|....*...
gi 19114212 529 YREAELYLSEVLNGDLEL 546
Cdd:COG3063  75 YDEALAYLERALELDPSA 92
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 259-553 3.24e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 47.00  E-value: 3.24e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   259 LAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPYRLDDMDTYSNVLFVLENKsklgflAQVASSIDKFRP 338
Cdd:TIGR02917 148 YEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNVDALLLKGDLLLSLGNI------ELALAAYRKAIA 221

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   339 ETCSIIGNYYSL------LSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGL 412
Cdd:TIGR02917 222 LRPNNIAVLLALatilieAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPEYLPALLLA 301

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   413 GQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNS 492
Cdd:TIGR02917 302 GASEYQLGNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                         250       260       270       280       290       300
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 19114212   493 AASMYKQCikteeTEISPETIKARIWLARWELGKKNYREAELYLSEVLNGDLELEEAKALL 553
Cdd:TIGR02917 382 AAEYLAKA-----TELDPENAAARTQLGISKLSQGDPSEAIADLETAAQLDPELGRADLLL 437
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 425-521 7.87e-05

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 42.29  E-value: 7.87e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 425 ALYYFQRATALRPYDQRMWQA---LGNCYEKIDRPQEAIKSYKRALL---GSQTNSSILVRLGNLYEELQDLNSAASMYK 498
Cdd:COG1729  12 AIAAFKAFLKRYPNSPLAPDAlywLGEAYYALGDYDEAAEAFEKLLKrypDSPKAPDALLKLGLSYLELGDYDKARATLE 91

                        90       100
                ....*....|....*....|...
gi 19114212 499 QCIKTEETeiSPETIKARIWLAR 521
Cdd:COG1729  92 ELIKKYPD--SEAAKEARARLAR 112
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 381-467 2.38e-04

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 40.75  E-value: 2.38e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 381 EYVELKNTHAAIESYRLAVDVNRKDY---RAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQAL---GNCYEKID 454
Cdd:COG1729   2 ALLKAGDYDEAIAAFKAFLKRYPNSPlapDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKAPDALlklGLSYLELG 81

                        90
                ....*....|...
gi 19114212 455 RPQEAIKSYKRAL 467
Cdd:COG1729  82 DYDKARATLEELI 94
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
313-467 2.78e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 42.59  E-value: 2.78e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 313 VLFVLENKSKLGFLAQVASSIDKFRPETCSIIGNYYSLLSEHEKAVTYFKRAL------QLNRNYLSAWTLMGHEYVELK 386
Cdd:COG4785   8 LLLALALAAAAASKAAILLAALLFAAVLALAIALADLALALAAAALAAAALAAeridraLALPDLAQLYYERGVAYDSLG 87

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 387 NTHAAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRA 466
Cdd:COG4785  88 DYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKA 167


                .
gi 19114212 467 L 467
Cdd:COG4785 168 L 168
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 428-468 5.52e-04

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 42.20  E-value: 5.52e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|.
gi 19114212 428 YFQRATALRPyDQRMWQALGNCYEKIDRPQEAIKSYKRALL 468
Cdd:COG3071 280 YLEAALALRP-SAEAYAELARLLEQLGDPEEAAEHYRKALA 319
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
438-563 5.88e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 41.79  E-value: 5.88e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 438 YDQRMwqALGNCYEKIDRPQEAIKSYKRALLG-SQTNSSILVRLGNLYEELQDLNSAASMYKQCIKTEETEISPET--IK 514
Cdd:COG4700  89 VQNRV--RLADALLELGRYDEAIELYEEALTGiFADDPHILLGLAQALFELGRYAEALETLEKLIAKNPDFKSSDAhlLY 166

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 515 ARIW--LARWELGKKNYR---------EAELYLSEVLNGDLELEEAKALLRELRSRMEHS 563
Cdd:COG4700 167 ARALeaLGDLEAAEAELEalarrysgpEARYRYAKFLARQGRTAEAKELLEEILDEAKHM 226
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 254-402 6.14e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.18  E-value: 6.14e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 254 SAYEKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgflaqvassi 333
Cdd:COG4783  22 EAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDP---DEPEARLN--------------------- 77

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 19114212 334 dkfrpetcsiIGNYYSLLSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVN 402
Cdd:COG4783  78 ----------LGLALLKAGDYDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 281-405 8.60e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 39.60  E-value: 8.60e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 281 YDSRDFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgfLAQVassidkfrpetcsiignyYSLLSEHEKAVTY 360
Cdd:COG4235  28 LRLGRYDEALAAYEKALRLDP---DNADALLD-------------LAEA------------------LLAAGDTEEAEEL 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 19114212 361 FKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKD 405
Cdd:COG4235  74 LERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPAD 118
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
390-533 9.02e-04

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 41.05  E-value: 9.02e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 390 AAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYY-FQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRALL 468
Cdd:COG4785  22 AAILLAALLFAAVLALAIALADLALALAAAALAAAALAAeRIDRALALPDLAQLYYERGVAYDSLGDYDLAIADFDQALE 101

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 19114212 469 GSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPETIKARIWLARWELGKKNYREAE 533
Cdd:COG4785 102 LDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL-----ELDPDYAYAYLNRGIALYYLGRYELAI 161
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 257-540 1.47e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 41.61  E-value: 1.47e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   257 EKLAEAEI-IFPNS---RYLKtqrALLTYDSRDFDEAESLFENILTNDPYRLDdmdtysnvlfvlenksklgfLAQVASS 332
Cdd:TIGR02917 247 EKHADALLkKAPNSplaHYLK---ALVDFQKKNYEDARETLQDALKSAPEYLP--------------------ALLLAGA 303

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   333 IdkfrpetcsiignYYSLlSEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYRAWYGL 412
Cdd:TIGR02917 304 S-------------EYQL-GNLEQAYQYLNQILKYAPNSHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLL 369

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   413 GQTYEVLDMHFYALYYFQRATALRPYDQRMWQALGNCYEKIDRPQEAIKSYKRAL-LGSQT------------------- 472
Cdd:TIGR02917 370 GEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLSQGDPSEAIADLETAAqLDPELgradlllilsylrsgqfdk 449

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   473 --------------NSSILVRLGNLYEELQDLNSAASMYKQCIKteeteISPETIKARIWLARWELGKKNYREAELYLSE 538
Cdd:TIGR02917 450 alaaakklekkqpdNASLHNLLGAIYLGKGDLAKAREAFEKALS-----IEPDFFPAAANLARIDIQEGNPDDAIQRFEK 524


                  ..
gi 19114212   539 VL 540
Cdd:TIGR02917 525 VL 526
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 454-511 1.95e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 40.30  E-value: 1.95e-03
                        10        20        30        40        50
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 19114212 454 DRPQEAIKSYKRALLGSQTNSSILVRLGNLYEELQDLNSAASMYKQCIkteetEISPE 511
Cdd:cd24142  14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAI-----ELDPD 66
TPR_1 pfam00515
Tetratricopeptide repeat;
338-371 2.11e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 35.86  E-value: 2.11e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 19114212   338 PETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNY 371
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
LcrH_SycD TIGR02552
type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in ...
 366-475 2.46e-03

type III secretion low calcium response chaperone LcrH/SycD; Genes in this family are found in type III secretion operons. LcrH, from Yersinia is believed to have a regulatory function in the low-calcium response of the secretion system. The same protein is also known as SycD (SYC = Specific Yop Chaperone) for its chaperone role. In Pseudomonas, where the homolog is known as PcrH, the chaperone role has been demonstrated and the regulatory role appears to be absent. ScyD/LcrH contains three central tetratricopeptide-like repeats that are predicted to fold into an all-alpha-helical array.


Pssm-ID: 274197 [Multi-domain]  Cd Length: 135  Bit Score: 38.43  E-value: 2.46e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212   366 QLNRNYLSAWTLMGH-EYVElknthaAIESYRLAVDVNRKDYRAWYGLGQTYEVLDMHFYALYYFQRATALRPYDQRMWQ 444
Cdd:TIGR02552  16 QLEQIYALAYNLYQQgRYDE------ALKLFQLLAAYDPYNSRYWLGLAACCQMLKEYEEAIDAYALAAALDPDDPRPYF 89

                          90       100       110
                  ....*....|....*....|....*....|.
gi 19114212   445 ALGNCYEKIDRPQEAIKSYKRALLGSQTNSS 475
Cdd:TIGR02552  90 HAAECLLALGEPESALKALDLAIEICGENPE 120
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 338-371 2.58e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.50  E-value: 2.58e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 19114212    338 PETCSIIGNYYSLLSEHEKAVTYFKRALQLNRNY 371
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 352-432 3.18e-03

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 39.92  E-value: 3.18e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 352 SEHEKAVTYFKRALQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVN-RKDYRAWYGLGQTYEVLDmhfyALYYFQ 430
Cdd:cd24142  14 GNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAIELDpDGGYEKYLYLGQLSGGEE----ALQYYE 89


                ..
gi 19114212 431 RA 432
Cdd:cd24142  90 KG 91
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
285-407 5.09e-03

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 36.69  E-value: 5.09e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114212 285 DFDEAESLFENILTNDPyrlDDMDTYSNvlfvlenksklgflaqvassidkfrpetcsiIGNYYSLLSEHEKAVTyFKRA 364
Cdd:COG3063   7 DLEEAEEYYEKALELDP---DNADALNN-------------------------------LGLLLLEQGRYDEAIA-LEKA 51

                        90       100       110       120
                ....*....|....*....|....*....|....*....|...
gi 19114212 365 LQLNRNYLSAWTLMGHEYVELKNTHAAIESYRLAVDVNRKDYR 407
Cdd:COG3063  52 LKLDPNNAEALLNLAELLLELGDYDEALAYLERALELDPSALR 94
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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