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Conserved domains on  [gi|19114780|ref|NP_593868|]
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Brix domain-containing protein Rpf1 [Schizosaccharomyces pombe]

Protein Classification

Brix domain-containing protein( domain architecture ID 10657983)

Brix domain-containing protein similar to Homo sapiens ribosome production factor 1 and U3 small nucleolar ribonucleoprotein protein IMP4

CATH:  3.40.50.10480
Gene Ontology:  GO:0019843|GO:0006364
PubMed:  11406393
SCOP:  4004748

Graphical summary

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List of domain hits

Name Accession Description Interval E-value
Brix smart00879
The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from ...
97-272 9.66e-46

The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


:

Pssm-ID: 214879 [Multi-domain]  Cd Length: 180  Bit Score: 152.89  E-value: 9.66e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780     97 LVTTSKRASRKCYDFASELLDCFPNAEFRKRtGDIEVHEIAEAAAKRGYTDLLVLNEDRKKTN--ALTLVHLPNGPSFYF 174
Cdd:smart00879   1 LITTSRKPSKRTRQLAKDLRRLFPPSTKINR-GKNKLNELLEFASEKGNTDLLVVFESSSKGRplNLTIYRLPNGPTLDF 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780    175 TLSNLQTAKEISNHGR---STGHIPELIINNFSTRLGMTVARAFQSLFIQTPQI-----QGRQVVTIHCQRDFLFFRRHR 246
Cdd:smart00879  80 KILNVSLRKELKGFKTgncLTGSRPLLIFNNFFTELGKLIKELFQDLFPGPPEHkkslpGLRRVVTFSNQDDYIFFRHYR 159
                          170       180
                   ....*....|....*....|....*.
gi 19114780    247 YAFREKsnmpdGIGTGLQELGPRFTM 272
Cdd:smart00879 160 IKFGKK-----KPRVELQEIGPRFTL 180
 
Name Accession Description Interval E-value
Brix smart00879
The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from ...
97-272 9.66e-46

The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


Pssm-ID: 214879 [Multi-domain]  Cd Length: 180  Bit Score: 152.89  E-value: 9.66e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780     97 LVTTSKRASRKCYDFASELLDCFPNAEFRKRtGDIEVHEIAEAAAKRGYTDLLVLNEDRKKTN--ALTLVHLPNGPSFYF 174
Cdd:smart00879   1 LITTSRKPSKRTRQLAKDLRRLFPPSTKINR-GKNKLNELLEFASEKGNTDLLVVFESSSKGRplNLTIYRLPNGPTLDF 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780    175 TLSNLQTAKEISNHGR---STGHIPELIINNFSTRLGMTVARAFQSLFIQTPQI-----QGRQVVTIHCQRDFLFFRRHR 246
Cdd:smart00879  80 KILNVSLRKELKGFKTgncLTGSRPLLIFNNFFTELGKLIKELFQDLFPGPPEHkkslpGLRRVVTFSNQDDYIFFRHYR 159
                          170       180
                   ....*....|....*....|....*.
gi 19114780    247 YAFREKsnmpdGIGTGLQELGPRFTM 272
Cdd:smart00879 160 IKFGKK-----KPRVELQEIGPRFTL 180
Brix pfam04427
Brix domain;
101-275 3.58e-21

Brix domain;


Pssm-ID: 461304 [Multi-domain]  Cd Length: 180  Bit Score: 88.41  E-value: 3.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   101 SKRASRKCYDFASELLDCFPN--AEFRKRtgdiEVHEIaeaaakRGYTDLLVLNEdrKKTNALTLVHL-----PNGPSFY 173
Cdd:pfam04427   1 GRKTSSRLRQLLKDLRSLMKPhtASFLKR----NSNPL------EDVTHLEFLSE--KNDCSLFVFGShskkrPNGPTLE 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   174 FTLSNLQTAKEISNHGRST-GHIPELIIN-NFSTRLGMT-VARAFQSLFiQTPQI---QGRQVVTIHC---QRDFLFFrR 244
Cdd:pfam04427  69 FGVENYSLMKDLKGTGNCLkGSRPLLVFNgSFFSDPNFKlLKSLFQDLF-RVPPInlkGIDRVILFSAydnQPDKIWF-R 146
                         170       180       190
                  ....*....|....*....|....*....|....
gi 19114780   245 HrYAFREKSNMPDGIGT---GLQELGPRFTMRLR 275
Cdd:pfam04427 147 H-YQIRLKEKKKSGTKLprvELVEIGPRFDLKLR 179
PRK03972 PRK03972
ribosomal biogenesis protein; Validated
96-218 4.14e-04

ribosomal biogenesis protein; Validated


Pssm-ID: 179689  Cd Length: 208  Bit Score: 40.66  E-value: 4.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   96 LLVTTSKRASRKCYDFASELLDCFPNAEFRKRtGDIEVHEIAEAAAKRGYTDLLVLNEDRKKTNALTLVHL-PNGPSF-- 172
Cdd:PRK03972   2 MLITTSHRPTRRTRSFGHDLERVFPNSLYLTR-GKKTIQDLLMEAYDRGYERLLIINVWKGNPLKMTFIKVgPEDWGYlg 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 19114780  173 YFTLSNLQTAKEISNHGRS--TGHIPELIINnfSTRLG---MTVARAFQSL 218
Cdd:PRK03972  81 YLYLHGIKLQREMGFRNLRpiREDMPLVITT--AKRVGldhMAFAQVFAEL 129
 
Name Accession Description Interval E-value
Brix smart00879
The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from ...
97-272 9.66e-46

The Brix domain is found in a number of eukaryotic proteins; Members include SSF proteins from yeast and humans, Arabidopsis thaliana Peter Pan-like protein and several hypothetical proteins.


Pssm-ID: 214879 [Multi-domain]  Cd Length: 180  Bit Score: 152.89  E-value: 9.66e-46
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780     97 LVTTSKRASRKCYDFASELLDCFPNAEFRKRtGDIEVHEIAEAAAKRGYTDLLVLNEDRKKTN--ALTLVHLPNGPSFYF 174
Cdd:smart00879   1 LITTSRKPSKRTRQLAKDLRRLFPPSTKINR-GKNKLNELLEFASEKGNTDLLVVFESSSKGRplNLTIYRLPNGPTLDF 79
                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780    175 TLSNLQTAKEISNHGR---STGHIPELIINNFSTRLGMTVARAFQSLFIQTPQI-----QGRQVVTIHCQRDFLFFRRHR 246
Cdd:smart00879  80 KILNVSLRKELKGFKTgncLTGSRPLLIFNNFFTELGKLIKELFQDLFPGPPEHkkslpGLRRVVTFSNQDDYIFFRHYR 159
                          170       180
                   ....*....|....*....|....*.
gi 19114780    247 YAFREKsnmpdGIGTGLQELGPRFTM 272
Cdd:smart00879 160 IKFGKK-----KPRVELQEIGPRFTL 180
Brix pfam04427
Brix domain;
101-275 3.58e-21

Brix domain;


Pssm-ID: 461304 [Multi-domain]  Cd Length: 180  Bit Score: 88.41  E-value: 3.58e-21
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   101 SKRASRKCYDFASELLDCFPN--AEFRKRtgdiEVHEIaeaaakRGYTDLLVLNEdrKKTNALTLVHL-----PNGPSFY 173
Cdd:pfam04427   1 GRKTSSRLRQLLKDLRSLMKPhtASFLKR----NSNPL------EDVTHLEFLSE--KNDCSLFVFGShskkrPNGPTLE 68
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   174 FTLSNLQTAKEISNHGRST-GHIPELIIN-NFSTRLGMT-VARAFQSLFiQTPQI---QGRQVVTIHC---QRDFLFFrR 244
Cdd:pfam04427  69 FGVENYSLMKDLKGTGNCLkGSRPLLVFNgSFFSDPNFKlLKSLFQDLF-RVPPInlkGIDRVILFSAydnQPDKIWF-R 146
                         170       180       190
                  ....*....|....*....|....*....|....
gi 19114780   245 HrYAFREKSNMPDGIGT---GLQELGPRFTMRLR 275
Cdd:pfam04427 147 H-YQIRLKEKKKSGTKLprvELVEIGPRFDLKLR 179
PRK03972 PRK03972
ribosomal biogenesis protein; Validated
96-218 4.14e-04

ribosomal biogenesis protein; Validated


Pssm-ID: 179689  Cd Length: 208  Bit Score: 40.66  E-value: 4.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 19114780   96 LLVTTSKRASRKCYDFASELLDCFPNAEFRKRtGDIEVHEIAEAAAKRGYTDLLVLNEDRKKTNALTLVHL-PNGPSF-- 172
Cdd:PRK03972   2 MLITTSHRPTRRTRSFGHDLERVFPNSLYLTR-GKKTIQDLLMEAYDRGYERLLIINVWKGNPLKMTFIKVgPEDWGYlg 80
                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 19114780  173 YFTLSNLQTAKEISNHGRS--TGHIPELIINnfSTRLG---MTVARAFQSL 218
Cdd:PRK03972  81 YLYLHGIKLQREMGFRNLRpiREDMPLVITT--AKRVGldhMAFAQVFAEL 129
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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